Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8in2_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ILE 2.A N LYS 156.A O no hydrogen 3.287 N/A THR 5.A N PHE 260.A O no hydrogen 2.942 N/A THR 5.A OG1 ALA 231.A O no hydrogen 2.923 N/A PHE 6.A N ILE 162.A O no hydrogen 3.130 N/A PHE 7.A N TYR 258.A O no hydrogen 2.973 N/A ILE 8.A N GLY 164.A O no hydrogen 2.916 N/A SER 9.A OG GLY 256.A O no hydrogen 2.771 N/A HIS 10.A N GLY 166.A O no hydrogen 2.857 N/A MET 14.A N THR 12.A OG1 no hydrogen 3.245 N/A MET 15.A N THR 12.A O no hydrogen 2.892 N/A ALA 16.A N PRO 13.A O no hydrogen 2.956 N/A ILE 17.A N MET 14.A O no hydrogen 2.859 N/A ASP 18.A N MET 14.A O no hydrogen 2.656 N/A SER 20.A N ASP 18.A OD2 no hydrogen 2.808 N/A SER 20.A OG ASP 18.A OD2 no hydrogen 2.194 N/A LYS 21.A NZ ASP 249.A OD1 no hydrogen 2.909 N/A SER 23.A OG SER 247.A OG no hydrogen 3.176 N/A LYS 24.A N LYS 21.A O no hydrogen 2.979 N/A LYS 24.A NZ GLU 28.A OE2 no hydrogen 2.757 N/A PHE 26.A N PRO 22.A O no hydrogen 2.937 N/A LEU 27.A N SER 23.A O no hydrogen 2.919 N/A GLU 28.A N LYS 24.A O no hydrogen 2.885 N/A SER 29.A N LYS 25.A O no hydrogen 3.183 N/A SER 29.A OG PHE 26.A O no hydrogen 2.895 N/A TRP 30.A N LEU 27.A O no hydrogen 3.051 N/A LYS 33.A N SER 29.A O no hydrogen 2.819 N/A ILE 34.A N TRP 30.A O no hydrogen 2.990 N/A PHE 35.A N TRP 30.A O no hydrogen 2.952 N/A LYS 37.A NZ ASN 1.A O no hydrogen 2.584 N/A LYS 37.A NZ ASN 1.A OD1 no hydrogen 3.542 N/A LYS 40.A N GLY 159.A O no hydrogen 2.582 N/A LYS 40.A NZ GLU 87.A OE2 no hydrogen 3.225 N/A ALA 41.A N GLY 159.A O no hydrogen 3.277 N/A ILE 42.A N PRO 130.A O no hydrogen 2.815 N/A LEU 43.A N LEU 161.A O no hydrogen 2.874 N/A VAL 44.A N CYS 132.A O no hydrogen 2.942 N/A ILE 45.A N ILE 163.A O no hydrogen 2.826 N/A SER 46.A N LEU 134.A O no hydrogen 3.192 N/A SER 46.A OG ASP 113.A OD1 no hydrogen 2.690 N/A ALA 47.A N SER 165.A O no hydrogen 2.978 N/A HIS 48.A N SER 46.A OG no hydrogen 3.204 N/A HIS 48.A NE2 HIS 10.A NE2 no hydrogen 2.194 N/A THR 51.A N VAL 136.A O no hydrogen 3.161 N/A THR 51.A OG1 GLN 53.A O no hydrogen 2.549 N/A THR 51.A OG1 SER 55.A OG no hydrogen 3.070 N/A THR 51.A OG1 SER 135.A OG no hydrogen 2.764 N/A SER 55.A OG THR 51.A OG1 no hydrogen 3.070 N/A SER 55.A OG GLN 53.A O no hydrogen 2.898 N/A VAL 56.A N ASN 105.A O no hydrogen 3.038 N/A ASN 57.A N GLN 133.A O no hydrogen 3.260 N/A ASN 57.A ND2 GLY 111.A O no hydrogen 3.071 N/A VAL 58.A N ASP 107.A O no hydrogen 3.018 N/A ASN 62.A N ALA 82.A O no hydrogen 2.913 N/A ASN 62.A ND2 ALA 82.A O no hydrogen 2.777 N/A ASN 62.A ND2 VAL 131.A O no hydrogen 3.077 N/A ILE 65.A N LEU 112.A O no hydrogen 3.009 N/A TYR 66.A OH PHE 78.A O no hydrogen 2.338 N/A PHE 68.A N TYR 66.A O no hydrogen 2.728 N/A PHE 71.A N TYR 76.A OH no hydrogen 3.371 N/A LEU 75.A N PRO 72.A O no hydrogen 3.074 N/A TYR 76.A N ALA 73.A O no hydrogen 2.927 N/A TYR 76.A OH PHE 68.A O no hydrogen 3.218 N/A GLN 77.A N ARG 74.A O no hydrogen 3.072 N/A TYR 80.A N THR 64.A OG1 no hydrogen 2.854 N/A TYR 80.A OH TYR 124.A O no hydrogen 2.608 N/A ALA 82.A N TYR 80.A O no hydrogen 2.726 N/A GLY 84.A N ASP 60.A O no hydrogen 3.233 N/A LEU 88.A N SER 85.A OG no hydrogen 2.930 N/A ALA 89.A N SER 85.A O no hydrogen 2.702 N/A ASN 90.A N PRO 86.A O no hydrogen 2.938 N/A ARG 91.A N GLU 87.A O no hydrogen 2.974 N/A ARG 91.A NH2 GLU 158.A OE2 no hydrogen 3.149 N/A ILE 92.A N LEU 88.A O no hydrogen 2.881 N/A GLN 93.A N ALA 89.A O no hydrogen 2.968 N/A ASP 94.A N ASN 90.A O no hydrogen 2.915 N/A LEU 95.A N ARG 91.A O no hydrogen 2.947 N/A LEU 96.A N ILE 92.A O no hydrogen 2.865 N/A ALA 97.A N GLN 93.A O no hydrogen 2.881 N/A GLY 98.A N ASP 94.A O no hydrogen 2.848 N/A SER 99.A N LEU 96.A O no hydrogen 3.018 N/A SER 99.A OG LEU 95.A O no hydrogen 3.228 N/A GLY 100.A N ALA 97.A O no hydrogen 3.254 N/A PHE 101.A N LEU 96.A O no hydrogen 3.340 N/A ASN 105.A N PRO 54.A O no hydrogen 2.799 N/A ASP 107.A N VAL 56.A O no hydrogen 2.933 N/A LYS 108.A NZ THR 106.A O no hydrogen 3.211 N/A LYS 108.A NZ THR 106.A OG1 no hydrogen 2.178 N/A LYS 109.A N ASP 107.A OD1 no hydrogen 2.693 N/A ARG 110.A N ASP 107.A OD1 no hydrogen 2.818 N/A ARG 110.A NH2 ASP 113.A OD2 no hydrogen 2.617 N/A LEU 112.A N ASP 63.A O no hydrogen 2.942 N/A HIS 114.A N ASP 67.A OD1 no hydrogen 2.986 N/A HIS 114.A ND1 ASP 67.A OD1 no hydrogen 2.570 N/A ALA 116.A N ASP 113.A O no hydrogen 2.624 N/A TRP 117.A N ASP 113.A O no hydrogen 3.151 N/A TRP 117.A NE1 ILE 65.A O no hydrogen 2.614 N/A VAL 118.A N HIS 114.A O no hydrogen 3.014 N/A LEU 120.A N ALA 116.A O no hydrogen 3.066 N/A MET 121.A N TRP 117.A O no hydrogen 2.896 N/A LEU 122.A N PRO 119.A O no hydrogen 3.046 N/A MET 123.A N PRO 119.A O no hydrogen 2.915 N/A TYR 124.A N LEU 120.A O no hydrogen 2.919 N/A ALA 127.A N TYR 124.A O no hydrogen 3.440 N/A VAL 131.A N PRO 83.A O no hydrogen 2.799 N/A CYS 132.A N ILE 42.A O no hydrogen 2.846 N/A CYS 132.A SG ASN 57.A O no hydrogen 3.209 N/A GLN 133.A NE2 ASP 113.A OD2 no hydrogen 2.330 N/A LEU 134.A N VAL 44.A O no hydrogen 2.803 N/A SER 135.A N SER 55.A O no hydrogen 3.365 N/A SER 135.A OG THR 51.A OG1 no hydrogen 2.764 N/A VAL 136.A N TRP 49.A O no hydrogen 3.100 N/A GLN 137.A N HIS 145.A NE2 no hydrogen 3.035 N/A GLN 137.A NE2 SER 135.A O no hydrogen 2.873 N/A GLN 137.A NE2 SER 135.A OG no hydrogen 3.223 N/A SER 138.A OG GLU 50.A OE1 no hydrogen 2.311 N/A LEU 140.A N GLN 137.A O no hydrogen 3.129 N/A HIS 144.A N ASP 141.A OD1 no hydrogen 2.917 N/A HIS 144.A NE2 GLN 137.A OE1 no hydrogen 2.505 N/A HIS 145.A ND1 ASP 141.A O no hydrogen 2.805 N/A TYR 146.A N GLY 142.A O no hydrogen 2.949 N/A LYS 147.A N THR 143.A O no hydrogen 2.979 N/A LEU 148.A N HIS 144.A O no hydrogen 2.934 N/A GLY 149.A N HIS 145.A O no hydrogen 2.934 N/A GLN 150.A N TYR 146.A O no hydrogen 2.895 N/A ALA 151.A N LYS 147.A O no hydrogen 2.828 N/A LEU 152.A N LEU 148.A O no hydrogen 3.011 N/A ALA 153.A N GLN 150.A O no hydrogen 2.942 N/A LEU 155.A N LEU 152.A O no hydrogen 2.855 N/A LYS 156.A N ALA 153.A O no hydrogen 3.301 N/A LYS 156.A NZ ALA 153.A O no hydrogen 3.390 N/A ASP 157.A N PRO 154.A O no hydrogen 3.261 N/A GLU 158.A N LEU 155.A O no hydrogen 3.101 N/A GLY 159.A N LYS 156.A O no hydrogen 3.208 N/A VAL 160.A N LEU 155.A O no hydrogen 3.360 N/A LEU 161.A N ALA 41.A O no hydrogen 2.906 N/A ILE 163.A N LEU 43.A O no hydrogen 2.892 N/A GLY 164.A N PHE 6.A O no hydrogen 2.923 N/A SER 165.A N ILE 45.A O no hydrogen 2.896 N/A SER 165.A OG GLY 115.A O no hydrogen 2.674 N/A GLY 166.A N ILE 8.A O no hydrogen 3.082 N/A SER 167.A N HIS 224.A O no hydrogen 3.065 N/A SER 167.A OG GLY 166.A O no hydrogen 3.060 N/A ALA 168.A N SER 9.A OG no hydrogen 3.332 N/A HIS 170.A N ALA 218.A O no hydrogen 2.907 N/A THR 175.A N SER 172.A O no hydrogen 2.940 N/A THR 175.A OG1 SER 172.A O no hydrogen 3.438 N/A CYS 178.A N GLY 250.A O no hydrogen 2.958 N/A ALA 183.A N GLY 251.A O no hydrogen 2.786 N/A ALA 187.A N ALA 183.A O no hydrogen 3.096 N/A ALA 188.A N PRO 184.A O no hydrogen 2.959 N/A PHE 189.A N TRP 185.A O no hydrogen 2.995 N/A ASP 190.A N ALA 186.A O no hydrogen 2.932 N/A SER 191.A N ALA 187.A O no hydrogen 2.871 N/A TRP 192.A N ALA 188.A O no hydrogen 2.971 N/A TRP 192.A NE1 GLU 204.A OE1 no hydrogen 2.925 N/A LEU 193.A N PHE 189.A O no hydrogen 2.929 N/A GLU 194.A N ASP 190.A O no hydrogen 2.975 N/A THR 195.A N SER 191.A O no hydrogen 3.012 N/A THR 195.A OG1 SER 191.A O no hydrogen 2.667 N/A ALA 196.A N TRP 192.A O no hydrogen 2.917 N/A LEU 197.A N LEU 193.A O no hydrogen 2.816 N/A THR 198.A N GLU 194.A O no hydrogen 2.869 N/A THR 198.A OG1 GLU 194.A O no hydrogen 2.715 N/A ASN 199.A ND2 THR 195.A O no hydrogen 3.030 N/A GLY 200.A N LEU 197.A O no hydrogen 3.019 N/A SER 201.A N ALA 196.A O no hydrogen 2.916 N/A TYR 202.A OH SER 239.A OG no hydrogen 2.851 N/A VAL 205.A N SER 201.A O no hydrogen 3.417 N/A ASN 206.A N TYR 202.A O no hydrogen 2.974 N/A LYS 207.A N GLU 203.A O no hydrogen 3.053 N/A TYR 208.A N VAL 205.A O no hydrogen 3.278 N/A TYR 208.A OH TYR 226.A OH no hydrogen 3.217 N/A THR 210.A N LYS 207.A O no hydrogen 3.199 N/A THR 210.A OG1 LYS 207.A O no hydrogen 3.561 N/A LYS 211.A N TYR 208.A O no hydrogen 3.096 N/A ALA 212.A N TYR 208.A O no hydrogen 2.914 N/A ASN 214.A ND2 TRP 185.A O no hydrogen 3.314 N/A ALA 218.A N ASN 214.A O no hydrogen 2.966 N/A HIS 219.A N TRP 215.A O no hydrogen 2.556 N/A HIS 219.A NE2 ALA 168.A O no hydrogen 2.881 N/A GLU 223.A N GLU 223.A OE2 no hydrogen 2.903 N/A HIS 224.A ND1 GLU 223.A OE1 no hydrogen 2.836 N/A HIS 224.A NE2 HIS 48.A NE2 no hydrogen 2.816 N/A PHE 225.A N PRO 222.A O no hydrogen 2.778 N/A TYR 226.A N PRO 222.A O no hydrogen 3.216 N/A TYR 226.A OH LEU 140.A O no hydrogen 3.075 N/A TYR 226.A OH TYR 208.A OH no hydrogen 3.217 N/A LEU 228.A N PHE 225.A O no hydrogen 3.089 N/A HIS 229.A ND1 PHE 225.A O no hydrogen 3.214 N/A HIS 229.A NE2 VAL 205.A O no hydrogen 2.745 N/A VAL 230.A N TYR 226.A O no hydrogen 3.045 N/A ALA 231.A N PRO 227.A O no hydrogen 2.989 N/A MET 232.A N LEU 228.A O no hydrogen 2.882 N/A GLY 233.A N HIS 229.A O no hydrogen 2.879 N/A ALA 234.A N VAL 230.A O no hydrogen 2.932 N/A ALA 235.A N ALA 231.A O no hydrogen 3.006 N/A GLY 236.A N MET 232.A O no hydrogen 3.453 N/A GLU 237.A N GLU 237.A OE2 no hydrogen 2.512 N/A SER 239.A OG TYR 202.A OH no hydrogen 2.851 N/A SER 239.A OG GLY 236.A O no hydrogen 3.418 N/A LYS 240.A N THR 261.A O no hydrogen 2.842 N/A LYS 240.A NZ THR 198.A O no hydrogen 3.311 N/A LYS 240.A NZ ALA 241.A O no hydrogen 2.851 N/A GLU 242.A N LYS 259.A O no hydrogen 2.927 N/A ILE 244.A N SER 257.A O no hydrogen 2.755 N/A HIS 245.A N SER 257.A O no hydrogen 3.174 N/A HIS 245.A NE2 SER 247.A OG no hydrogen 3.214 N/A SER 247.A OG SER 23.A OG no hydrogen 3.176 N/A SER 247.A OG HIS 245.A NE2 no hydrogen 3.214 N/A ASP 249.A N MET 253.A O no hydrogen 3.213 N/A SER 254.A OG ASP 190.A OD2 no hydrogen 2.708 N/A SER 254.A OG ASN 246.A OD1 no hydrogen 2.812 N/A TYR 255.A N SER 247.A O no hydrogen 2.737 N/A TYR 255.A OH ASP 249.A OD2 no hydrogen 2.237 N/A GLY 256.A N SER 254.A OG no hydrogen 3.138 N/A SER 257.A N HIS 245.A O no hydrogen 2.901 N/A SER 257.A OG TYR 255.A O no hydrogen 3.057 N/A TYR 258.A N PHE 7.A O no hydrogen 2.909 N/A LYS 259.A N GLU 242.A O no hydrogen 2.881 N/A PHE 260.A N THR 5.A O no hydrogen 2.792 N/A THR 261.A N LYS 240.A O no hydrogen 2.837 N/A SER 262.A N LYS 3.A O no hydrogen 2.889 N/A SER 262.A OG LYS 3.A O no hydrogen 2.824 N/A THR 263.A OG1 ASN 238.A O no hydrogen 2.984 N/A