Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8ipx_B.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ARG 9.A NH1 GLY 11.A O no hydrogen 3.379 N/A GLY 14.A N SER 12.A OG no hydrogen 3.111 N/A LYS 19.A N PRO 17.A O no hydrogen 2.984 N/A ARG 20.A NE GLN 270.A OE1 no hydrogen 3.388 N/A SER 21.A N TYR 273.A O no hydrogen 3.022 N/A SER 21.A OG ARG 23.A O no hydrogen 2.691 N/A SER 21.A OG TYR 273.A O no hydrogen 3.531 N/A HIS 24.A ND1 TYR 273.A OH no hydrogen 2.595 N/A LYS 27.A N HIS 275.A NE2 no hydrogen 3.117 N/A SER 37.A OG ASP 35.A OD1 no hydrogen 3.345 N/A SER 37.A OG ASP 35.A OD2 no hydrogen 3.056 N/A LYS 38.A N ASP 35.A O no hydrogen 3.356 N/A HIS 41.A N ASN 185.A O no hydrogen 2.891 N/A HIS 41.A ND1 PRO 39.A O no hydrogen 2.808 N/A THR 43.A OG1 GLN 183.A O no hydrogen 2.416 N/A PHE 45.A N LEU 346.A O no hydrogen 2.670 N/A GLY 47.A N LEU 344.A O no hydrogen 2.892 N/A TYR 48.A N GLU 79.A O no hydrogen 2.987 N/A TYR 48.A OH THR 165.A OG1 no hydrogen 3.363 N/A TYR 48.A OH HIS 178.A ND1 no hydrogen 2.468 N/A LYS 49.A N ARG 342.A O no hydrogen 3.183 N/A LYS 49.A NZ VAL 336.A O no hydrogen 3.256 N/A LYS 49.A NZ GLY 338.A O no hydrogen 2.835 N/A ALA 50.A N ILE 77.A O no hydrogen 2.948 N/A THR 53.A N VAL 75.A O no hydrogen 2.871 N/A THR 53.A OG1 HIS 54.A O no hydrogen 3.423 N/A THR 53.A OG1 ASP 368.A O no hydrogen 3.032 N/A HIS 54.A N THR 53.A OG1 no hydrogen 2.560 N/A ILE 55.A N GLU 73.A O no hydrogen 2.929 N/A VAL 56.A N PHE 366.A O no hydrogen 3.172 N/A ARG 57.A N VAL 71.A O no hydrogen 2.918 N/A ARG 57.A NE GLU 73.A OE1 no hydrogen 3.086 N/A ARG 57.A NE GLU 73.A OE2 no hydrogen 2.889 N/A ARG 57.A NH2 GLU 73.A OE2 no hydrogen 3.286 N/A VAL 59.A N LYS 69.A O no hydrogen 3.267 N/A ARG 61.A N ASN 67.A OD1 no hydrogen 2.977 N/A SER 64.A OG ARG 61.A O no hydrogen 2.661 N/A LYS 68.A N VAL 59.A O no hydrogen 2.766 N/A LYS 69.A NZ ASN 67.A O no hydrogen 3.345 N/A VAL 71.A N ARG 57.A O no hydrogen 2.966 N/A GLU 73.A N ILE 55.A O no hydrogen 2.894 N/A VAL 75.A N THR 53.A O no hydrogen 2.900 N/A THR 76.A N LEU 332.A O no hydrogen 2.873 N/A THR 76.A OG1 GLY 51.A O no hydrogen 3.097 N/A ILE 77.A N GLY 51.A O no hydrogen 2.983 N/A VAL 78.A N VAL 330.A O no hydrogen 2.974 N/A GLU 79.A N TYR 48.A O no hydrogen 2.775 N/A THR 80.A N ASP 328.A O no hydrogen 2.669 N/A THR 80.A OG1 ASP 328.A O no hydrogen 3.029 N/A MET 83.A N VAL 204.A O no hydrogen 2.948 N/A VAL 84.A N HIS 164.A O no hydrogen 2.945 N/A VAL 85.A N GLN 202.A O no hydrogen 2.961 N/A VAL 86.A N ILE 162.A O no hydrogen 2.875 N/A GLY 87.A N ILE 162.A O no hydrogen 3.238 N/A ILE 88.A N VAL 104.A O no hydrogen 2.917 N/A VAL 89.A N ARG 160.A O no hydrogen 2.909 N/A GLY 90.A N LYS 102.A O no hydrogen 2.843 N/A TYR 91.A N VAL 158.A O no hydrogen 2.907 N/A TYR 91.A OH GLU 181.A OE1 no hydrogen 2.962 N/A VAL 92.A N ARG 99.A O no hydrogen 2.885 N/A THR 94.A N GLY 97.A O no hydrogen 2.860 N/A THR 94.A OG1 GLY 97.A O no hydrogen 2.698 N/A GLY 97.A N THR 94.A O no hydrogen 2.937 N/A ARG 99.A N VAL 92.A O no hydrogen 2.921 N/A PHE 101.A N GLY 90.A O no hydrogen 2.838 N/A LYS 102.A N GLY 90.A O no hydrogen 3.072 N/A THR 103.A OG1 ILE 88.A O no hydrogen 2.977 N/A VAL 104.A N ILE 88.A O no hydrogen 2.873 N/A PHE 105.A N TYR 132.A OH no hydrogen 3.381 N/A LYS 114.A N SER 110.A O no hydrogen 2.907 N/A LYS 114.A NZ ALA 128.A O no hydrogen 2.428 N/A ARG 116.A N CYS 113.A O no hydrogen 3.449 N/A ARG 116.A NE ALA 177.A O no hydrogen 3.006 N/A ARG 116.A NH2 ALA 177.A O no hydrogen 2.944 N/A TYR 118.A N ARG 115.A O no hydrogen 3.455 N/A SER 124.A OG ASN 120.A O no hydrogen 3.540 N/A SER 124.A OG TRP 121.A O no hydrogen 3.120 N/A LYS 126.A NZ TRP 121.A O no hydrogen 2.801 N/A LYS 126.A NZ SER 124.A O no hydrogen 3.387 N/A THR 130.A OG1 LYS 127.A O no hydrogen 2.730 N/A CYS 133.A N PHE 129.A O no hydrogen 2.961 N/A CYS 133.A SG THR 130.A O no hydrogen 3.337 N/A LYS 134.A NZ THR 130.A O no hydrogen 2.459 N/A LYS 135.A N TYR 132.A O no hydrogen 3.510 N/A GLN 137.A N LYS 134.A O no hydrogen 3.295 N/A ASP 138.A N LYS 134.A O no hydrogen 2.937 N/A GLU 139.A N ASP 138.A OD1 no hydrogen 2.885 N/A LYS 142.A N ASP 138.A O no hydrogen 3.266 N/A GLN 144.A N ASP 140.A O no hydrogen 2.976 N/A LEU 145.A N GLY 141.A O no hydrogen 2.878 N/A GLU 146.A N LYS 142.A O no hydrogen 2.957 N/A LYS 147.A N LYS 143.A O no hydrogen 2.946 N/A ASP 148.A N GLN 144.A O no hydrogen 2.917 N/A PHE 149.A N LEU 145.A O no hydrogen 2.916 N/A SER 150.A N GLU 146.A O no hydrogen 2.930 N/A SER 150.A OG GLU 146.A O no hydrogen 2.966 N/A SER 150.A OG LYS 147.A O no hydrogen 2.848 N/A SER 151.A N LYS 147.A O no hydrogen 2.912 N/A MET 152.A N ASP 148.A O no hydrogen 2.935 N/A LYS 153.A N PHE 149.A O no hydrogen 2.933 N/A LYS 153.A NZ ASP 194.A OD1 no hydrogen 3.525 N/A LYS 154.A N SER 150.A O no hydrogen 2.906 N/A LYS 154.A NZ TYR 155.A OH no hydrogen 3.267 N/A TYR 155.A N SER 151.A O no hydrogen 2.930 N/A CYS 156.A N MET 152.A O no hydrogen 2.924 N/A GLN 157.A N TYR 91.A O no hydrogen 3.134 N/A ARG 160.A N VAL 89.A O no hydrogen 3.331 N/A ARG 160.A NH1 GLU 181.A OE1 no hydrogen 3.304 N/A VAL 161.A N ILE 182.A O no hydrogen 2.866 N/A ILE 162.A N GLY 87.A O no hydrogen 2.518 N/A ALA 163.A N MET 180.A O no hydrogen 2.936 N/A HIS 164.A N VAL 84.A O no hydrogen 2.938 N/A HIS 164.A ND1 THR 165.A O no hydrogen 2.689 N/A THR 165.A N HIS 178.A O no hydrogen 2.972 N/A THR 165.A OG1 TYR 48.A OH no hydrogen 3.363 N/A MET 167.A N GLU 112.A OE1 no hydrogen 3.081 N/A ARG 168.A NE GLU 112.A OE2 no hydrogen 3.036 N/A GLN 174.A NE2 LYS 176.A O no hydrogen 3.212 N/A ALA 177.A N GLU 112.A O no hydrogen 3.259 N/A HIS 178.A N THR 165.A OG1 no hydrogen 3.263 N/A HIS 178.A ND1 TYR 48.A OH no hydrogen 2.468 N/A MET 180.A N ALA 163.A O no hydrogen 2.921 N/A ILE 182.A N VAL 161.A O no hydrogen 2.889 N/A GLN 183.A NE2 ASN 185.A OD1 no hydrogen 3.050 N/A VAL 184.A N ILE 159.A O no hydrogen 3.049 N/A ASN 185.A N HIS 41.A O no hydrogen 3.073 N/A ASN 185.A ND2 PRO 32.A O no hydrogen 2.917 N/A GLY 186.A N ASP 34.A OD1 no hydrogen 2.677 N/A LYS 192.A N THR 188.A O no hydrogen 2.976 N/A LYS 192.A NZ ASP 34.A OD2 no hydrogen 2.684 N/A LYS 192.A NZ VAL 184.A O no hydrogen 3.516 N/A LEU 193.A N VAL 189.A O no hydrogen 2.904 N/A ASP 194.A N ALA 190.A O no hydrogen 2.953 N/A TRP 195.A N GLU 191.A O no hydrogen 2.941 N/A ALA 196.A N LYS 192.A O no hydrogen 2.916 N/A ARG 197.A N LEU 193.A O no hydrogen 2.933 N/A ARG 197.A NH1 GLU 146.A OE1 no hydrogen 3.364 N/A ARG 197.A NH2 GLU 146.A OE2 no hydrogen 2.739 N/A GLU 198.A N ASP 194.A O no hydrogen 2.953 N/A ARG 199.A N TRP 195.A O no hydrogen 2.925 N/A LEU 200.A N ARG 197.A O no hydrogen 3.381 N/A GLU 201.A N VAL 85.A O no hydrogen 3.078 N/A VAL 204.A N MET 83.A O no hydrogen 2.851 N/A VAL 209.A N VAL 206.A O no hydrogen 3.209 N/A PHE 210.A N VAL 206.A O no hydrogen 2.920 N/A ASP 213.A N ILE 283.A O no hydrogen 2.951 N/A ILE 216.A N LYS 281.A O no hydrogen 2.879 N/A ASP 217.A N ARG 347.A O no hydrogen 2.896 N/A VAL 218.A N GLU 278.A O no hydrogen 2.873 N/A ILE 219.A N THR 345.A O no hydrogen 2.850 N/A GLY 220.A N ARG 276.A O no hydrogen 2.981 N/A THR 222.A N HIS 274.A O no hydrogen 2.903 N/A THR 222.A OG1 HIS 274.A O no hydrogen 3.394 N/A LYS 225.A N LYS 271.A O no hydrogen 3.211 N/A LYS 228.A N GLY 269.A O no hydrogen 2.709 N/A SER 232.A OG GLY 229.A O no hydrogen 3.265 N/A ARG 233.A N GLY 229.A O no hydrogen 2.909 N/A ARG 233.A NE GLN 270.A O no hydrogen 2.980 N/A ARG 233.A NH1 ARG 267.A O no hydrogen 2.845 N/A ARG 233.A NH2 ARG 18.A O no hydrogen 3.343 N/A ARG 233.A NH2 GLN 270.A O no hydrogen 3.343 N/A TRP 234.A N VAL 230.A O no hydrogen 2.930 N/A LEU 239.A N LEU 247.A O no hydrogen 3.180 N/A THR 243.A OG1 PRO 240.A O no hydrogen 2.853 N/A LYS 249.A NZ ARG 245.A O no hydrogen 2.913 N/A CYS 252.A SG GLY 254.A O no hydrogen 3.346 N/A GLY 269.A N LYS 228.A O no hydrogen 3.053 N/A GLN 270.A NE2 GLY 272.A O no hydrogen 3.247 N/A LYS 271.A N GLY 226.A O no hydrogen 3.111 N/A TYR 273.A N LYS 223.A O no hydrogen 3.410 N/A TYR 273.A OH HIS 24.A ND1 no hydrogen 2.595 N/A HIS 274.A N THR 222.A OG1 no hydrogen 3.282 N/A HIS 274.A ND1 LYS 19.A O no hydrogen 2.717 N/A ARG 276.A N GLY 220.A O no hydrogen 2.878 N/A ARG 276.A NH1 HIS 275.A O no hydrogen 3.090 N/A THR 277.A OG1 VAL 218.A O no hydrogen 3.296 N/A GLU 278.A N VAL 218.A O no hydrogen 2.851 N/A LYS 281.A N ILE 216.A O no hydrogen 2.945 N/A LYS 281.A NZ CYS 335.A O no hydrogen 2.679 N/A LYS 282.A NZ ASP 213.A O no hydrogen 3.054 N/A ILE 283.A N GLU 214.A O no hydrogen 2.956 N/A TYR 284.A N MET 331.A O no hydrogen 2.996 N/A TYR 284.A OH GLU 73.A OE1 no hydrogen 2.341 N/A GLY 287.A N PHE 329.A O no hydrogen 2.631 N/A TYR 290.A N THR 326.A O no hydrogen 3.135 N/A TYR 290.A OH SER 312.A OG no hydrogen 3.241 N/A LEU 297.A N LEU 291.A O no hydrogen 2.895 N/A ASN 300.A ND2 GLY 289.A O no hydrogen 2.480 N/A SER 303.A OG LYS 299.A O no hydrogen 3.379 N/A THR 304.A OG1 THR 304.A O no hydrogen 2.450 N/A SER 309.A OG ASP 307.A O no hydrogen 3.103 N/A LYS 311.A NZ ASP 307.A OD2 no hydrogen 3.132 N/A LYS 311.A NZ ILE 367.A O no hydrogen 2.914 N/A LYS 311.A NZ THR 369.A OG1 no hydrogen 2.784 N/A LYS 311.A NZ GLN 379.A OE1 no hydrogen 3.062 N/A SER 312.A OG TYR 290.A OH no hydrogen 3.241 N/A ASN 314.A N SER 312.A OG no hydrogen 3.339 N/A ASN 314.A ND2 VAL 325.A O no hydrogen 2.986 N/A GLY 318.A N PRO 315.A O no hydrogen 3.185 N/A PHE 319.A N GLY 323.A O no hydrogen 3.129 N/A TYR 322.A OH GLU 79.A OE1 no hydrogen 2.366 N/A VAL 325.A N ASN 314.A OD1 no hydrogen 2.656 N/A THR 326.A N GLU 79.A OE2 no hydrogen 3.424 N/A ASN 327.A N GLU 79.A OE2 no hydrogen 3.408 N/A ASN 327.A ND2 LEU 169.A O no hydrogen 3.372 N/A VAL 330.A N VAL 78.A O no hydrogen 2.848 N/A MET 331.A N LYS 285.A O no hydrogen 2.988 N/A LEU 332.A N THR 76.A O no hydrogen 2.862 N/A LYS 333.A N LYS 282.A O no hydrogen 3.083 N/A GLY 334.A N ALA 74.A O no hydrogen 2.842 N/A LYS 340.A N THR 339.A OG1 no hydrogen 2.691 N/A LYS 341.A N LYS 49.A O no hydrogen 3.290 N/A LYS 341.A NZ HIS 321.A O no hydrogen 3.100 N/A ARG 342.A NH1 THR 222.A O no hydrogen 3.439 N/A LEU 344.A N GLY 47.A O no hydrogen 2.887 N/A THR 345.A N ILE 219.A O no hydrogen 2.961 N/A THR 345.A OG1 GLY 26.A O no hydrogen 3.437 N/A LEU 346.A N PHE 45.A O no hydrogen 2.745 N/A ARG 347.A N ASP 217.A O no hydrogen 2.944 N/A ARG 347.A NH1 LYS 348.A O no hydrogen 2.785 N/A LYS 348.A N THR 43.A O no hydrogen 3.145 N/A LYS 348.A NZ VAL 209.A O no hydrogen 3.429 N/A LYS 348.A NZ GLU 214.A OE2 no hydrogen 3.422 N/A SER 349.A OG MET 215.A O no hydrogen 3.017 N/A GLN 353.A NE2 ASN 280.A OD1 no hydrogen 3.475 N/A LYS 365.A NZ GLU 58.A OE1 no hydrogen 3.553 N/A ASP 368.A N HIS 54.A O no hydrogen 3.405 N/A THR 369.A N GLN 379.A OE1 no hydrogen 2.863 N/A THR 369.A OG1 GLN 379.A OE1 no hydrogen 2.793 N/A THR 370.A OG1 ASP 368.A OD1 no hydrogen 3.289 N/A THR 370.A OG1 ASP 368.A OD2 no hydrogen 2.812 N/A SER 371.A OG LEU 316.A O no hydrogen 3.208 N/A LYS 372.A NZ THR 370.A O no hydrogen 2.472 N/A PHE 373.A N SER 371.A OG no hydrogen 3.424 N/A GLN 379.A N GLU 383.A OE1 no hydrogen 2.880 N/A GLN 379.A NE2 ASP 368.A OD1 no hydrogen 2.778 N/A THR 380.A N GLU 383.A OE1 no hydrogen 3.383 N/A LYS 384.A N THR 380.A O no hydrogen 3.008 N/A LYS 385.A N MET 381.A O no hydrogen 2.902 N/A ALA 386.A N GLU 382.A O no hydrogen 2.897 N/A PHE 387.A N GLU 383.A O no hydrogen 2.947 N/A MET 388.A N LYS 384.A O no hydrogen 2.936 N/A GLY 389.A N LYS 385.A O no hydrogen 2.918 N/A ARG 395.A N LEU 391.A O no hydrogen 2.964 N/A ILE 396.A N LYS 392.A O no hydrogen 2.923 N/A ALA 397.A N LYS 393.A O no hydrogen 2.893 N/A LYS 398.A N ASP 394.A O no hydrogen 2.928 N/A GLU 399.A N ARG 395.A O no hydrogen 2.961 N/A GLU 400.A N ILE 396.A O no hydrogen 2.897 N/A GLY 401.A N ALA 397.A O no hydrogen 2.904 N/A