Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8iue_M.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ASP 1.A N ASP 1.A OD1 no hydrogen 2.465 N/A ASP 9.A N GLY 117.A O no hydrogen 3.379 N/A TYR 11.A N LEU 119.A O no hydrogen 2.890 N/A TYR 11.A OH SER 226.A O no hydrogen 2.738 N/A ALA 13.A N LEU 121.A O no hydrogen 3.181 N/A SER 15.A OG TYR 219.A O no hydrogen 2.297 N/A GLU 18.A N GLU 18.A OE1 no hydrogen 2.728 N/A TYR 21.A OH HIS 125.A ND1 no hydrogen 2.878 N/A LEU 22.A N GLY 126.A O no hydrogen 3.217 N/A ARG 28.A N TYR 25.A O no hydrogen 3.314 N/A THR 33.A OG1 ASP 35.A OD2 no hydrogen 2.988 N/A LEU 40.A N GLU 54.A O no hydrogen 2.956 N/A LYS 43.A N GLU 52.A O no hydrogen 2.910 N/A ILE 44.A N VAL 201.A O no hydrogen 3.332 N/A LYS 45.A NZ HIS 195.A O no hydrogen 2.369 N/A LYS 45.A NZ GLU 198.A O no hydrogen 3.320 N/A LYS 47.A N GLU 198.A OE2 no hydrogen 3.120 N/A GLU 52.A N LYS 43.A O no hydrogen 2.884 N/A LEU 53.A N PHE 97.A O no hydrogen 2.912 N/A GLU 54.A N SER 41.A O no hydrogen 2.906 N/A MET 55.A N GLN 95.A O no hydrogen 2.902 N/A ALA 56.A N PRO 38.A O no hydrogen 3.183 N/A ILE 57.A N ASP 93.A O no hydrogen 3.213 N/A TYR 64.A N ASN 61.A O no hydrogen 3.262 N/A TYR 64.A OH MET 92.A O no hydrogen 3.072 N/A CYS 65.A SG SER 67.A OG no hydrogen 3.052 N/A GLY 69.A N CYS 65.A O no hydrogen 2.999 N/A GLU 70.A N ARG 66.A O no hydrogen 2.900 N/A GLN 71.A N SER 67.A O no hydrogen 2.915 N/A ILE 72.A N LYS 68.A O no hydrogen 2.900 N/A ALA 73.A N GLY 69.A O no hydrogen 2.909 N/A LEU 74.A N GLU 70.A O no hydrogen 2.907 N/A ASN 75.A N GLN 71.A O no hydrogen 2.907 N/A VAL 76.A N ILE 72.A O no hydrogen 2.913 N/A ASP 77.A N ALA 73.A O no hydrogen 3.214 N/A SER 85.A OG ASP 77.A OD2 no hydrogen 2.718 N/A SER 85.A OG TYR 87.A O no hydrogen 2.534 N/A THR 86.A N ASP 77.A OD1 no hydrogen 3.401 N/A THR 86.A OG1 ASP 77.A OD1 no hydrogen 3.203 N/A THR 86.A OG1 ASP 77.A OD2 no hydrogen 3.169 N/A TYR 87.A N SER 85.A OG no hydrogen 3.312 N/A LYS 90.A NZ ALA 79.A O no hydrogen 2.885 N/A LYS 94.A NZ GLU 54.A OE1 no hydrogen 2.798 N/A GLN 95.A N MET 55.A O no hydrogen 2.889 N/A THR 96.A OG1 SER 133.A O no hydrogen 3.249 N/A PHE 97.A N LEU 53.A O no hydrogen 2.893 N/A CYS 98.A N ARG 131.A O no hydrogen 2.909 N/A CYS 98.A SG SER 99.A O no hydrogen 3.570 N/A SER 99.A OG VAL 51.A O no hydrogen 2.566 N/A SER 100.A N GLN 129.A O no hydrogen 2.892 N/A GLN 101.A NE2 THR 103.A O no hydrogen 3.349 N/A THR 102.A N ILE 127.A O no hydrogen 3.319 N/A THR 102.A OG1 ILE 127.A O no hydrogen 3.141 N/A THR 103.A OG1 ASN 105.A OD1 no hydrogen 3.139 N/A THR 106.A OG1 LEU 124.A O no hydrogen 3.047 N/A TYR 109.A N THR 106.A O no hydrogen 3.264 N/A ALA 111.A N THR 122.A O no hydrogen 2.891 N/A LEU 113.A N HIS 120.A O no hydrogen 2.891 N/A ARG 115.A N GLU 118.A O no hydrogen 2.875 N/A ARG 115.A NE GLU 118.A OE2 no hydrogen 3.369 N/A LEU 119.A N ASP 9.A O no hydrogen 2.913 N/A HIS 120.A N LEU 113.A O no hydrogen 2.905 N/A LEU 121.A N TYR 11.A O no hydrogen 2.894 N/A THR 122.A N ALA 111.A O no hydrogen 2.916 N/A HIS 125.A N LEU 20.A O no hydrogen 3.122 N/A HIS 125.A ND1 TYR 21.A OH no hydrogen 2.878 N/A LEU 128.A N LEU 22.A O no hydrogen 3.075 N/A GLN 129.A N SER 100.A O no hydrogen 2.913 N/A LEU 130.A N GLN 24.A O no hydrogen 3.014 N/A ARG 131.A N CYS 98.A O no hydrogen 2.896 N/A SER 133.A N THR 96.A O no hydrogen 2.938 N/A LYS 139.A N SER 135.A O no hydrogen 3.279 N/A ALA 140.A N TYR 136.A O no hydrogen 2.895 N/A ASP 141.A N LEU 137.A O no hydrogen 2.897 N/A ALA 142.A N ASP 138.A O no hydrogen 2.914 N/A LYS 143.A N LYS 139.A O no hydrogen 2.889 N/A LYS 143.A NZ GLU 146.A OE2 no hydrogen 2.959 N/A HIS 144.A N ALA 140.A O no hydrogen 2.882 N/A ARG 145.A N ASP 141.A O no hydrogen 2.909 N/A GLU 146.A N ALA 142.A O no hydrogen 2.920 N/A ARG 147.A N LYS 143.A O no hydrogen 2.877 N/A ARG 147.A NH2 LEU 74.A O no hydrogen 3.413 N/A GLU 148.A N HIS 144.A O no hydrogen 2.909 N/A ALA 149.A N ARG 145.A O no hydrogen 2.915 N/A ALA 150.A N GLU 146.A O no hydrogen 2.885 N/A ASN 151.A N ARG 147.A O no hydrogen 2.890 N/A GLU 152.A N GLU 148.A O no hydrogen 2.902 N/A ALA 153.A N ALA 149.A O no hydrogen 2.914 N/A GLY 154.A N ALA 150.A O no hydrogen 2.883 N/A ALA 180.A N SER 177.A OG no hydrogen 3.397 N/A ARG 181.A N SER 177.A O no hydrogen 2.995 N/A GLN 182.A N GLU 178.A O no hydrogen 2.902 N/A ARG 183.A N GLN 179.A O no hydrogen 2.905 N/A ARG 183.A NE GLN 179.A OE1 no hydrogen 3.242 N/A ARG 184.A N ALA 180.A O no hydrogen 2.891 N/A VAL 185.A N ARG 181.A O no hydrogen 2.916 N/A GLN 186.A N GLN 182.A O no hydrogen 2.893 N/A SER 187.A N ARG 184.A O no hydrogen 3.222 N/A SER 187.A OG ARG 184.A O no hydrogen 2.386 N/A GLU 189.A N GLU 189.A OE1 no hydrogen 2.621 N/A LEU 191.A N SER 187.A O no hydrogen 3.339 N/A GLN 192.A N TYR 188.A O no hydrogen 2.910 N/A LYS 193.A N GLU 189.A O no hydrogen 2.894 N/A LYS 194.A N PHE 190.A O no hydrogen 2.898 N/A HIS 195.A N LEU 191.A O no hydrogen 2.912 N/A ALA 196.A N GLN 192.A O no hydrogen 2.896 N/A GLU 197.A N LYS 193.A O no hydrogen 2.900 N/A LEU 203.A N ALA 42.A O no hydrogen 3.402 N/A ASP 210.A N GLY 207.A O no hydrogen 3.247 N/A SER 211.A OG ASP 210.A OD1 no hydrogen 3.550 N/A SER 213.A N ASP 210.A O no hydrogen 3.193 N/A SER 213.A OG LEU 208.A O no hydrogen 2.486 N/A SER 213.A OG ASP 210.A O no hydrogen 2.348 N/A HIS 215.A N SER 211.A O no hydrogen 2.908 N/A GLU 216.A N ARG 212.A O no hydrogen 2.909 N/A ARG 217.A N SER 213.A O no hydrogen 2.897 N/A TYR 219.A N GLU 216.A O no hydrogen 3.128 N/A LEU 221.A N GLN 218.A O no hydrogen 3.274 N/A CYS 222.A SG LEU 12.A O no hydrogen 3.238 N/A CYS 222.A SG HIS 120.A ND1 no hydrogen 3.859 N/A GLU 232.A N ASN 230.A OD1 no hydrogen 3.066 N/A GLU 239.A N SER 236.A OG no hydrogen 3.395 N/A TYR 240.A N SER 236.A O no hydrogen 2.969 N/A LEU 241.A N PRO 237.A O no hydrogen 2.904 N/A MET 242.A N SER 238.A O no hydrogen 2.912 N/A MET 243.A N GLU 239.A O no hydrogen 2.899 N/A LEU 244.A N TYR 240.A O no hydrogen 2.911 N/A MET 245.A N LEU 241.A O no hydrogen 3.251 N/A SER 251.A OG ASN 274.A OD1 no hydrogen 3.218 N/A LEU 259.A N SER 255.A O no hydrogen 2.576 N/A ARG 260.A N MET 256.A O no hydrogen 2.907 N/A THR 261.A OG1 ALA 257.A O no hydrogen 3.562 N/A THR 261.A OG1 GLN 258.A O no hydrogen 3.106 N/A ASP 266.A N PRO 263.A O no hydrogen 3.177 N/A GLN 267.A N PRO 263.A O no hydrogen 3.013 N/A ILE 268.A N LEU 264.A O no hydrogen 2.917 N/A ILE 270.A N ASP 266.A O no hydrogen 2.911 N/A LEU 271.A N GLN 267.A O no hydrogen 2.914 N/A MET 272.A N ILE 268.A O no hydrogen 2.899 N/A LYS 273.A N LYS 269.A O no hydrogen 2.894 N/A ASN 274.A N ILE 270.A O no hydrogen 2.909 N/A ASN 274.A N LEU 271.A O no hydrogen 3.255 N/A VAL 275.A N LEU 271.A O no hydrogen 2.982 N/A LYS 276.A NZ HIS 374.A NE2 no hydrogen 3.051 N/A MET 278.A N TRP 311.A O no hydrogen 3.056 N/A LEU 283.A N PRO 279.A O no hydrogen 3.254 N/A MET 284.A N PHE 280.A O no hydrogen 2.918 N/A SER 285.A N ALA 281.A O no hydrogen 3.431 N/A SER 285.A OG ASN 282.A O no hydrogen 2.578 N/A LEU 286.A N ASN 282.A O no hydrogen 2.916 N/A LEU 287.A N LEU 283.A O no hydrogen 2.898 N/A GLY 288.A N MET 284.A O no hydrogen 2.982 N/A ILE 291.A N GLY 288.A O no hydrogen 3.386 N/A SER 293.A N ASP 292.A OD1 no hydrogen 2.586 N/A LEU 297.A N SER 293.A O no hydrogen 2.903 N/A ARG 298.A N VAL 294.A O no hydrogen 2.904 N/A GLY 299.A N ALA 295.A O no hydrogen 2.926 N/A ILE 300.A N VAL 296.A O no hydrogen 2.880 N/A GLN 301.A N LEU 297.A O no hydrogen 2.929 N/A LYS 302.A N GLY 299.A O no hydrogen 3.146 N/A VAL 303.A N ILE 300.A O no hydrogen 3.381 N/A MET 305.A N VAL 312.A O no hydrogen 2.893 N/A LEU 306.A N GLN 405.A OE1 no hydrogen 3.312 N/A VAL 307.A N ASN 310.A O no hydrogen 2.866 N/A GLN 308.A NE2 PHE 346.A O no hydrogen 2.593 N/A ASN 310.A N VAL 307.A O no hydrogen 2.915 N/A ASN 310.A ND2 PRO 389.A O no hydrogen 2.978 N/A TRP 311.A N MET 278.A O no hydrogen 3.392 N/A VAL 312.A N MET 305.A O no hydrogen 2.901 N/A LYS 314.A N VAL 303.A O no hydrogen 3.100 N/A LYS 314.A NZ LYS 302.A O no hydrogen 2.782 N/A SER 315.A OG CYS 336.A O no hydrogen 3.520 N/A SER 315.A OG ASP 340.A OD1 no hydrogen 2.457 N/A ILE 317.A N LYS 314.A O no hydrogen 3.355 N/A TYR 319.A N SER 315.A O no hydrogen 3.161 N/A SER 323.A N PRO 320.A O no hydrogen 3.307 N/A SER 323.A OG SER 324.A O no hydrogen 3.302 N/A SER 325.A N VAL 330.A O no hydrogen 2.977 N/A SER 325.A OG SER 328.A OG no hydrogen 3.041 N/A SER 325.A OG ASP 367.A OD1 no hydrogen 3.562 N/A SER 328.A N SER 325.A OG no hydrogen 3.284 N/A SER 328.A OG SER 325.A OG no hydrogen 3.041 N/A SER 328.A OG ASP 367.A OD2 no hydrogen 3.194 N/A GLY 329.A N SER 325.A O no hydrogen 2.888 N/A CYS 336.A N ALA 332.A O no hydrogen 2.894 N/A CYS 336.A SG ALA 332.A O no hydrogen 3.174 N/A ARG 337.A N GLU 333.A O no hydrogen 2.919 N/A GLY 338.A N VAL 334.A O no hydrogen 2.894 N/A ARG 339.A N LEU 335.A O no hydrogen 2.905 N/A ARG 339.A NH1 VAL 313.A O no hydrogen 2.437 N/A ASP 340.A N CYS 336.A O no hydrogen 2.892 N/A PHE 341.A N ARG 337.A O no hydrogen 2.906 N/A VAL 342.A N GLY 338.A O no hydrogen 2.907 N/A MET 343.A N ARG 339.A O no hydrogen 2.910 N/A TRP 344.A N ASP 340.A O no hydrogen 2.882 N/A LYS 345.A N PHE 341.A O no hydrogen 2.903 N/A PHE 346.A N VAL 342.A O no hydrogen 2.911 N/A THR 347.A N MET 343.A O no hydrogen 2.896 N/A THR 347.A OG1 MET 343.A O no hydrogen 3.344 N/A THR 347.A OG1 TRP 344.A O no hydrogen 2.478 N/A GLN 348.A N TRP 344.A O no hydrogen 2.910 N/A SER 349.A N LYS 345.A O no hydrogen 2.872 N/A ARG 350.A NE GLU 385.A OE2 no hydrogen 3.527 N/A ARG 350.A NH2 LEU 388.A O no hydrogen 3.060 N/A ALA 358.A N ARG 354.A O no hydrogen 2.910 N/A THR 359.A N LYS 355.A O no hydrogen 2.898 N/A THR 359.A OG1 LYS 355.A O no hydrogen 2.820 N/A VAL 360.A N GLU 356.A O no hydrogen 2.910 N/A THR 361.A N VAL 357.A O no hydrogen 2.899 N/A THR 361.A OG1 VAL 357.A O no hydrogen 2.580 N/A VAL 368.A N CYS 364.A O no hydrogen 3.249 N/A LYS 369.A N ALA 365.A O no hydrogen 2.911 N/A ASP 370.A N GLU 366.A O no hydrogen 2.894 N/A PHE 371.A N ASP 367.A O no hydrogen 2.917 N/A LEU 372.A N VAL 368.A O no hydrogen 2.911 N/A GLU 373.A N LYS 369.A O no hydrogen 2.920 N/A HIS 374.A N PHE 371.A O no hydrogen 3.501 N/A ALA 376.A N LEU 372.A O no hydrogen 2.971 N/A VAL 377.A N GLU 385.A O no hydrogen 2.900 N/A ARG 379.A N GLY 383.A O no hydrogen 2.887 N/A LYS 382.A N ARG 379.A O no hydrogen 3.478 N/A GLY 383.A N ARG 379.A O no hydrogen 2.915 N/A GLU 385.A N VAL 377.A O no hydrogen 3.101 N/A ILE 387.A N MET 375.A O no hydrogen 3.094 N/A ASP 391.A N GLN 308.A O no hydrogen 3.269 N/A GLU 393.A N GLU 393.A OE1 no hydrogen 2.747 N/A PHE 394.A N ASP 391.A OD1 no hydrogen 3.129 N/A LYS 396.A N GLY 392.A O no hydrogen 2.911 N/A LYS 397.A N GLU 393.A O no hydrogen 2.907 N/A HIS 398.A N PHE 394.A O no hydrogen 3.101 N/A HIS 398.A N ILE 395.A O no hydrogen 3.353 N/A HIS 398.A ND1 PHE 394.A O no hydrogen 3.299 N/A GLN 403.A N PRO 399.A O no hydrogen 2.909 N/A ARG 404.A N ASP 400.A O no hydrogen 2.912 N/A ARG 404.A NE ASP 400.A O no hydrogen 3.305 N/A GLN 405.A N VAL 401.A O no hydrogen 2.902 N/A HIS 406.A N VAL 402.A O no hydrogen 2.889 N/A MET 407.A N GLN 403.A O no hydrogen 2.901 N/A LEU 408.A N ARG 404.A O no hydrogen 2.938 N/A TRP 409.A N GLN 405.A O no hydrogen 2.861 N/A TRP 409.A NE1 LEU 306.A O no hydrogen 3.063 N/A THR 410.A N HIS 406.A O no hydrogen 2.914 N/A THR 410.A OG1 HIS 406.A O no hydrogen 3.527 N/A THR 410.A OG1 MET 407.A O no hydrogen 2.250 N/A ILE 412.A N LEU 408.A O no hydrogen 2.951 N/A GLN 413.A N TRP 409.A O no hydrogen 2.836 N/A GLN 413.A NE2 GLU 417.A OE2 no hydrogen 2.837 N/A ALA 414.A N THR 410.A O no hydrogen 2.927 N/A LYS 415.A N GLY 411.A O no hydrogen 2.922 N/A LEU 416.A N ILE 412.A O no hydrogen 2.900 N/A GLU 417.A N GLN 413.A O no hydrogen 2.877 N/A LYS 418.A N ALA 414.A O no hydrogen 2.919 N/A VAL 419.A N LYS 415.A O no hydrogen 2.918 N/A TYR 420.A N LEU 416.A O no hydrogen 2.892 N/A