Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8iw4_B.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ILE 6.A N ALA 267.A O no hydrogen 3.254 N/A ARG 11.A N ILE 300.A O no hydrogen 2.905 N/A LEU 14.A N LEU 298.A O no hydrogen 2.872 N/A HIS 17.A NE2 SER 35.A OG no hydrogen 2.277 N/A HIS 25.A N VAL 34.A O no hydrogen 2.883 N/A THR 28.A OG1 PRO 70.A O no hydrogen 2.601 N/A SER 30.A OG SER 30.A O no hydrogen 2.300 N/A SER 30.A OG THR 283.A OG1 no hydrogen 2.955 N/A SER 30.A OG ASP 285.A OD1 no hydrogen 3.156 N/A SER 30.A OG ASP 285.A OD2 no hydrogen 3.472 N/A ARG 31.A N ASP 29.A OD1 no hydrogen 2.836 N/A ARG 31.A NE ASP 46.A OD1 no hydrogen 2.439 N/A ARG 31.A NH2 ASP 46.A OD2 no hydrogen 3.020 N/A LEU 32.A N ASP 29.A OD1 no hydrogen 3.406 N/A LEU 33.A N TRP 45.A O no hydrogen 2.958 N/A VAL 34.A N HIS 25.A O no hydrogen 2.923 N/A SER 35.A N ILE 43.A O no hydrogen 2.927 N/A SER 35.A OG HIS 17.A NE2 no hydrogen 2.277 N/A ALA 36.A N ALA 23.A O no hydrogen 2.942 N/A SER 37.A N LYS 41.A O no hydrogen 2.928 N/A SER 37.A OG HIS 17.A ND1 no hydrogen 2.425 N/A GLN 38.A N LYS 20.A O no hydrogen 3.089 N/A GLY 40.A N SER 37.A O no hydrogen 3.467 N/A LYS 41.A NZ ALA 55.A O no hydrogen 3.513 N/A LEU 42.A N ILE 56.A O no hydrogen 2.889 N/A ILE 43.A N SER 35.A O no hydrogen 2.937 N/A ILE 44.A N HIS 54.A O no hydrogen 2.917 N/A TRP 45.A N LEU 33.A O no hydrogen 2.858 N/A TRP 45.A NE1 SER 35.A OG no hydrogen 3.128 N/A SER 47.A N ARG 31.A O no hydrogen 2.854 N/A THR 49.A OG1 ASP 46.A OD2 no hydrogen 2.627 N/A THR 49.A OG1 ASN 51.A OD1 no hydrogen 2.489 N/A VAL 53.A N ILE 44.A O no hydrogen 2.942 N/A LEU 58.A N GLY 40.A O no hydrogen 3.121 N/A MET 64.A N GLY 78.A O no hydrogen 2.905 N/A THR 65.A N GLY 78.A O no hydrogen 3.390 N/A CYS 66.A SG ALA 76.A O no hydrogen 3.739 N/A ALA 67.A N ALA 76.A O no hydrogen 3.283 N/A TYR 68.A N HIS 25.A ND1 no hydrogen 2.977 N/A ALA 69.A N TYR 74.A O no hydrogen 3.130 N/A GLY 72.A N ALA 69.A O no hydrogen 3.055 N/A ASN 73.A N SER 71.A OG no hydrogen 3.323 N/A VAL 75.A N TYR 87.A O no hydrogen 2.949 N/A ALA 76.A N ALA 67.A O no hydrogen 3.243 N/A CYS 77.A N SER 85.A O no hydrogen 2.940 N/A CYS 77.A SG SER 85.A O no hydrogen 3.964 N/A CYS 77.A SG TYR 87.A OH no hydrogen 3.855 N/A LEU 80.A N TRP 62.A O no hydrogen 3.304 N/A ASN 82.A ND2 GLY 107.A O no hydrogen 2.234 N/A CYS 84.A N LEU 102.A O no hydrogen 2.913 N/A CYS 84.A SG CYS 77.A O no hydrogen 3.701 N/A SER 85.A N CYS 77.A O no hydrogen 2.900 N/A SER 85.A OG GLU 101.A OE1 no hydrogen 3.340 N/A SER 85.A OG GLU 101.A OE2 no hydrogen 2.821 N/A ILE 86.A N ARG 100.A O no hydrogen 2.936 N/A TYR 87.A N VAL 75.A O no hydrogen 2.853 N/A ASN 88.A N ARG 97.A O no hydrogen 3.207 N/A LEU 89.A N ASN 73.A O no hydrogen 3.018 N/A LYS 90.A NZ ASN 73.A OD1 no hydrogen 3.403 N/A SER 99.A N ILE 86.A O no hydrogen 2.693 N/A SER 99.A OG ILE 86.A O no hydrogen 3.247 N/A ARG 100.A N ILE 86.A O no hydrogen 3.445 N/A ARG 100.A NE ILE 134.A O no hydrogen 2.965 N/A ARG 100.A NE GLU 135.A O no hydrogen 3.340 N/A ARG 100.A NH2 GLU 135.A O no hydrogen 3.045 N/A LEU 102.A N CYS 84.A O no hydrogen 2.892 N/A HIS 105.A NE2 THR 122.A OG1 no hydrogen 3.308 N/A THR 106.A N ASP 126.A OD1 no hydrogen 3.095 N/A THR 106.A OG1 ASP 126.A OD1 no hydrogen 2.791 N/A GLY 107.A N ASP 126.A OD1 no hydrogen 3.136 N/A TYR 108.A OH ASP 149.A OD2 no hydrogen 2.729 N/A LEU 109.A N GLY 79.A O no hydrogen 3.036 N/A SER 110.A N SER 123.A O no hydrogen 2.851 N/A SER 110.A OG SER 123.A O no hydrogen 2.964 N/A SER 110.A OG VAL 150.A O no hydrogen 2.665 N/A CYS 111.A N SER 123.A O no hydrogen 2.943 N/A CYS 111.A SG LEU 153.A O no hydrogen 3.855 N/A ARG 113.A N VAL 121.A O no hydrogen 2.923 N/A ARG 113.A NH1 CYS 66.A O no hydrogen 2.934 N/A ARG 113.A NH1 CYS 112.A O no hydrogen 2.892 N/A LEU 115.A N GLN 119.A O no hydrogen 3.326 N/A VAL 121.A N ARG 113.A O no hydrogen 2.885 N/A THR 122.A N ALA 130.A O no hydrogen 2.857 N/A THR 122.A OG1 HIS 105.A NE2 no hydrogen 3.308 N/A THR 122.A OG1 ALA 130.A O no hydrogen 3.387 N/A SER 123.A N CYS 111.A O no hydrogen 2.879 N/A SER 124.A OG ASP 126.A OD2 no hydrogen 3.332 N/A THR 128.A OG1 ASP 126.A OD2 no hydrogen 2.473 N/A CYS 129.A N PHE 143.A O no hydrogen 3.036 N/A CYS 129.A SG SER 164.A OG no hydrogen 3.470 N/A ALA 130.A N THR 122.A O no hydrogen 2.901 N/A LEU 131.A N THR 141.A O no hydrogen 2.907 N/A TRP 132.A N ILE 120.A O no hydrogen 2.927 N/A ILE 134.A N ASN 118.A O no hydrogen 2.959 N/A THR 136.A N ASP 133.A OD2 no hydrogen 2.908 N/A THR 136.A OG1 ASP 133.A OD2 no hydrogen 2.839 N/A THR 136.A OG1 THR 136.A O no hydrogen 2.266 N/A THR 140.A OG1 THR 141.A OG1 no hydrogen 3.256 N/A THR 141.A OG1 THR 140.A OG1 no hydrogen 3.256 N/A HIS 146.A ND1 ASP 168.A OD2 no hydrogen 3.228 N/A THR 147.A N ASP 168.A OD2 no hydrogen 3.331 N/A VAL 150.A N SER 124.A O no hydrogen 3.386 N/A MET 151.A N GLY 165.A O no hydrogen 2.921 N/A SER 152.A N GLY 165.A O no hydrogen 3.342 N/A SER 154.A N VAL 163.A O no hydrogen 3.356 N/A ALA 156.A N LEU 161.A O no hydrogen 3.168 N/A THR 159.A N ALA 156.A O no hydrogen 3.061 N/A SER 164.A N LYS 172.A O no hydrogen 2.887 N/A GLY 165.A N SER 152.A O no hydrogen 3.153 N/A CYS 167.A N ASP 149.A O no hydrogen 2.782 N/A CYS 167.A SG ASP 191.A OD2 no hydrogen 3.398 N/A SER 170.A OG ASP 168.A OD1 no hydrogen 2.439 N/A ALA 171.A N PHE 185.A O no hydrogen 2.913 N/A LYS 172.A N SER 164.A O no hydrogen 2.921 N/A LEU 173.A N GLN 183.A O no hydrogen 2.896 N/A VAL 176.A N ARG 160.A O no hydrogen 3.425 N/A GLY 179.A N ASP 175.A O no hydrogen 2.992 N/A CYS 181.A SG LEU 173.A O no hydrogen 3.923 N/A CYS 181.A SG GLN 183.A O no hydrogen 3.815 N/A CYS 181.A SG THR 184.A OG1 no hydrogen 3.524 N/A ARG 182.A N LEU 173.A O no hydrogen 3.095 N/A ARG 182.A NH1 ASP 175.A OD2 no hydrogen 3.377 N/A PHE 185.A N ALA 171.A O no hydrogen 2.886 N/A HIS 188.A NE2 THR 206.A OG1 no hydrogen 3.003 N/A ASN 193.A N GLY 207.A O no hydrogen 2.909 N/A ALA 194.A N GLY 207.A O no hydrogen 3.430 N/A CYS 196.A N ALA 205.A O no hydrogen 3.147 N/A CYS 196.A SG PHE 197.A O no hydrogen 3.828 N/A PHE 198.A N ALA 203.A O no hydrogen 2.622 N/A PHE 204.A N PHE 216.A O no hydrogen 2.893 N/A ALA 205.A N CYS 196.A O no hydrogen 2.952 N/A THR 206.A N ARG 214.A O no hydrogen 2.721 N/A THR 206.A OG1 HIS 188.A NE2 no hydrogen 3.003 N/A THR 206.A OG1 ARG 214.A O no hydrogen 3.385 N/A GLY 207.A N ALA 194.A O no hydrogen 3.161 N/A SER 208.A OG ASP 210.A OD1 no hydrogen 2.180 N/A SER 208.A OG THR 212.A O no hydrogen 3.438 N/A ASP 209.A N ASP 191.A O no hydrogen 3.307 N/A ASP 210.A N ASP 210.A OD1 no hydrogen 2.504 N/A THR 212.A OG1 SER 208.A OG no hydrogen 3.177 N/A THR 212.A OG1 ASP 210.A OD1 no hydrogen 2.988 N/A THR 212.A OG1 ASP 210.A OD2 no hydrogen 2.879 N/A CYS 213.A N TYR 226.A O no hydrogen 2.902 N/A ARG 214.A N THR 206.A O no hydrogen 2.740 N/A PHE 216.A N PHE 204.A O no hydrogen 2.915 N/A LEU 218.A N ASN 202.A O no hydrogen 2.935 N/A ASP 220.A N ASP 217.A O no hydrogen 3.308 N/A LEU 223.A N LEU 215.A O no hydrogen 2.768 N/A THR 225.A OG1 MET 224.A O no hydrogen 2.965 N/A TYR 226.A N CYS 213.A O no hydrogen 2.973 N/A TYR 226.A OH ALA 261.A O no hydrogen 3.325 N/A ILE 231.A N HIS 228.A O no hydrogen 3.169 N/A ILE 235.A N SER 208.A O no hydrogen 3.040 N/A THR 236.A N GLY 250.A O no hydrogen 3.276 N/A THR 236.A OG1 ASP 252.A OD2 no hydrogen 3.470 N/A THR 236.A OG1 VAL 277.A O no hydrogen 3.431 N/A SER 239.A N LEU 248.A O no hydrogen 3.051 N/A SER 239.A OG PHE 240.A O no hydrogen 3.518 N/A ARG 245.A NE ASP 260.A OD1 no hydrogen 2.711 N/A ARG 245.A NE ASP 260.A OD2 no hydrogen 3.529 N/A ARG 245.A NH2 ASP 1.A O no hydrogen 3.413 N/A ARG 245.A NH2 ASP 260.A OD2 no hydrogen 3.253 N/A LEU 248.A N SER 239.A O no hydrogen 2.908 N/A ALA 249.A N ASN 257.A O no hydrogen 3.071 N/A GLY 250.A N SER 237.A O no hydrogen 2.828 N/A ASP 252.A N GLY 234.A O no hydrogen 3.360 N/A CYS 256.A SG ALA 249.A O no hydrogen 2.476 N/A CYS 256.A SG ASN 257.A O no hydrogen 3.618 N/A ASN 257.A N ALA 249.A O no hydrogen 3.327 N/A VAL 258.A N GLY 268.A O no hydrogen 2.954 N/A TRP 259.A N LEU 247.A O no hydrogen 2.808 N/A ASP 260.A N ASP 265.A O no hydrogen 3.278 N/A ALA 261.A N ARG 245.A O no hydrogen 2.852 N/A LEU 262.A N ASP 260.A OD1 no hydrogen 3.089 N/A LYS 263.A N ASP 260.A OD1 no hydrogen 3.370 N/A ALA 264.A N ASP 260.A O no hydrogen 3.087 N/A ALA 267.A N VAL 258.A O no hydrogen 3.218 N/A LEU 270.A N CYS 256.A O no hydrogen 2.819 N/A ASP 274.A N ASP 295.A OD2 no hydrogen 3.402 N/A ARG 276.A N ASN 275.A OD1 no hydrogen 3.111 N/A ARG 276.A NE ASP 252.A OD1 no hydrogen 2.727 N/A ARG 276.A NH2 ASP 252.A OD1 no hydrogen 2.296 N/A ARG 276.A NH2 ASP 252.A OD2 no hydrogen 3.079 N/A VAL 277.A N TYR 251.A O no hydrogen 3.427 N/A SER 278.A N GLY 292.A O no hydrogen 3.107 N/A SER 278.A OG ILE 21.A O no hydrogen 2.704 N/A GLY 281.A N ALA 290.A O no hydrogen 2.889 N/A THR 283.A N ALA 288.A O no hydrogen 3.409 N/A THR 283.A OG1 SER 30.A OG no hydrogen 2.955 N/A THR 283.A OG1 ASP 285.A OD1 no hydrogen 3.214 N/A GLY 286.A N THR 283.A O no hydrogen 3.120 N/A MET 287.A N ASP 285.A OD1 no hydrogen 3.469 N/A VAL 289.A N TRP 301.A O no hydrogen 2.923 N/A ALA 290.A N GLY 281.A O no hydrogen 2.896 N/A THR 291.A N LYS 299.A O no hydrogen 2.896 N/A GLY 292.A N CYS 279.A O no hydrogen 2.911 N/A SER 293.A OG HIS 273.A ND1 no hydrogen 2.830 N/A SER 293.A OG ASP 295.A OD1 no hydrogen 2.143 N/A TRP 294.A N ARG 276.A O no hydrogen 3.231 N/A SER 296.A OG HIS 17.A O no hydrogen 3.297 N/A SER 296.A OG ASP 295.A O no hydrogen 2.325 N/A PHE 297.A N ASP 295.A OD1 no hydrogen 3.369 N/A LYS 299.A N THR 291.A O no hydrogen 2.923 N/A ILE 300.A N ARG 12.A O no hydrogen 3.277 N/A TRP 301.A N VAL 289.A O no hydrogen 2.869 N/A