Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8iz4_R.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): SER 4.A OG HIS 64.A O no hydrogen 3.290 N/A SER 4.A OG ASN 68.A OD1 no hydrogen 3.341 N/A VAL 6.A N LEU 2.A O no hydrogen 3.356 N/A LEU 7.A N LEU 3.A O no hydrogen 2.947 N/A THR 8.A N SER 4.A O no hydrogen 3.114 N/A THR 8.A OG1 SER 4.A O no hydrogen 2.911 N/A THR 9.A N THR 5.A O no hydrogen 3.249 N/A THR 9.A OG1 THR 5.A O no hydrogen 3.270 N/A SER 10.A N VAL 6.A O no hydrogen 2.760 N/A SER 10.A OG VAL 6.A O no hydrogen 2.720 N/A TYR 11.A N LEU 7.A O no hydrogen 2.881 N/A SER 12.A N THR 8.A O no hydrogen 3.163 N/A SER 12.A OG THR 8.A O no hydrogen 2.370 N/A VAL 13.A N THR 9.A O no hydrogen 3.450 N/A ILE 14.A N SER 10.A O no hydrogen 3.371 N/A PHE 15.A N TYR 11.A O no hydrogen 2.898 N/A ILE 16.A N SER 12.A O no hydrogen 3.181 N/A VAL 17.A N VAL 13.A O no hydrogen 2.938 N/A GLY 18.A N ILE 14.A O no hydrogen 2.629 N/A LEU 19.A N PHE 15.A O no hydrogen 3.031 N/A VAL 20.A N ILE 16.A O no hydrogen 3.231 N/A GLY 21.A N VAL 17.A O no hydrogen 2.877 N/A ASN 22.A N GLY 18.A O no hydrogen 2.950 N/A ASN 22.A ND2 GLY 18.A O no hydrogen 2.335 N/A ASN 22.A ND2 SER 261.A O no hydrogen 3.631 N/A ILE 23.A N LEU 19.A O no hydrogen 3.050 N/A ILE 24.A N VAL 20.A O no hydrogen 3.155 N/A ALA 25.A N GLY 21.A O no hydrogen 2.974 N/A LEU 26.A N ASN 22.A O no hydrogen 2.714 N/A TYR 27.A N ILE 23.A O no hydrogen 2.996 N/A TYR 27.A N ILE 24.A O no hydrogen 3.157 N/A VAL 28.A N ILE 24.A O no hydrogen 3.122 N/A PHE 29.A N ALA 25.A O no hydrogen 3.176 N/A GLY 31.A N TYR 27.A O no hydrogen 2.661 N/A ILE 32.A N TYR 27.A O no hydrogen 3.209 N/A HIS 33.A N VAL 28.A O no hydrogen 2.982 N/A ARG 36.A NE PHE 29.A O no hydrogen 2.344 N/A ARG 36.A NH2 PHE 29.A O no hydrogen 3.179 N/A SER 38.A OG ASP 101.A OD2 no hydrogen 3.075 N/A GLN 40.A NE2 TYR 268.A OH no hydrogen 3.326 N/A ILE 41.A N ASN 37.A O no hydrogen 3.102 N/A ILE 41.A N SER 38.A O no hydrogen 3.192 N/A TYR 42.A N SER 38.A O no hydrogen 3.326 N/A LEU 43.A N ILE 39.A O no hydrogen 2.966 N/A LEU 44.A N GLN 40.A O no hydrogen 2.961 N/A ASN 45.A N ILE 41.A O no hydrogen 3.156 N/A ASN 45.A ND2 ILE 41.A O no hydrogen 2.392 N/A VAL 46.A N TYR 42.A O no hydrogen 2.828 N/A ALA 47.A N LEU 43.A O no hydrogen 3.029 N/A ILE 48.A N LEU 44.A O no hydrogen 3.174 N/A ALA 49.A N ASN 45.A O no hydrogen 2.650 N/A ASP 50.A N VAL 46.A O no hydrogen 2.704 N/A LEU 51.A N ALA 47.A O no hydrogen 2.907 N/A LEU 52.A N ILE 48.A O no hydrogen 3.147 N/A LEU 53.A N ALA 49.A O no hydrogen 3.134 N/A ILE 54.A N ASP 50.A O no hydrogen 2.733 N/A PHE 55.A N LEU 51.A O no hydrogen 2.894 N/A CYS 56.A N LEU 52.A O no hydrogen 3.143 N/A CYS 56.A N LEU 53.A O no hydrogen 3.170 N/A CYS 56.A SG LEU 52.A O no hydrogen 3.208 N/A LEU 57.A N ILE 54.A O no hydrogen 3.039 N/A ARG 60.A N CYS 56.A O no hydrogen 3.414 N/A ARG 60.A NH1 GLU 251.A OE2 no hydrogen 2.293 N/A ILE 61.A N LEU 57.A O no hydrogen 2.575 N/A MET 62.A N PRO 58.A O no hydrogen 2.845 N/A TYR 63.A N PHE 59.A O no hydrogen 3.316 N/A HIS 64.A N ARG 60.A O no hydrogen 3.268 N/A ILE 65.A N ILE 61.A O no hydrogen 3.102 N/A ASN 66.A N MET 62.A O no hydrogen 3.240 N/A GLN 67.A N HIS 64.A O no hydrogen 3.314 N/A TRP 70.A N THR 143.A O no hydrogen 2.826 N/A TRP 70.A NE1 GLY 73.A O no hydrogen 3.062 N/A CYS 77.A N GLY 73.A O no hydrogen 3.309 N/A LYS 78.A N VAL 74.A O no hydrogen 3.249 N/A VAL 79.A N ILE 75.A O no hydrogen 3.056 N/A VAL 80.A N LEU 76.A O no hydrogen 2.763 N/A GLY 81.A N CYS 77.A O no hydrogen 2.443 N/A THR 82.A N LYS 78.A O no hydrogen 2.995 N/A THR 82.A OG1 LYS 78.A O no hydrogen 2.845 N/A LEU 83.A N VAL 79.A O no hydrogen 2.887 N/A PHE 84.A N VAL 80.A O no hydrogen 3.099 N/A MET 86.A N THR 82.A O no hydrogen 2.705 N/A ASN 87.A N LEU 83.A O no hydrogen 3.079 N/A ASN 87.A ND2 LEU 83.A O no hydrogen 2.508 N/A MET 88.A N PHE 84.A O no hydrogen 3.148 N/A TYR 89.A N TYR 85.A O no hydrogen 3.089 N/A TYR 89.A OH HIS 224.A NE2 no hydrogen 3.043 N/A ILE 90.A N MET 86.A O no hydrogen 2.997 N/A SER 91.A N ASN 87.A O no hydrogen 3.081 N/A SER 91.A OG ASP 50.A OD1 no hydrogen 2.689 N/A SER 91.A OG ASN 87.A O no hydrogen 3.078 N/A ILE 92.A N MET 88.A O no hydrogen 3.172 N/A ILE 93.A N TYR 89.A O no hydrogen 3.089 N/A LEU 94.A N ILE 90.A O no hydrogen 2.918 N/A LEU 95.A N SER 91.A O no hydrogen 2.772 N/A GLY 96.A N ILE 92.A O no hydrogen 2.953 N/A PHE 97.A N ILE 93.A O no hydrogen 3.072 N/A ILE 98.A N LEU 94.A O no hydrogen 2.812 N/A SER 99.A N LEU 95.A O no hydrogen 3.154 N/A SER 99.A OG LEU 95.A O no hydrogen 3.112 N/A LEU 100.A N GLY 96.A O no hydrogen 3.207 N/A ASP 101.A N PHE 97.A O no hydrogen 2.782 N/A ARG 102.A N ILE 98.A O no hydrogen 2.760 N/A TYR 103.A N SER 99.A O no hydrogen 2.981 N/A ILE 104.A N LEU 100.A O no hydrogen 3.247 N/A LYS 105.A N ASP 101.A O no hydrogen 3.132 N/A ILE 106.A N ARG 102.A O no hydrogen 3.192 N/A ASN 107.A N TYR 103.A O no hydrogen 2.829 N/A SER 112.A N THR 108.A O no hydrogen 3.459 N/A SER 112.A OG SER 38.A O no hydrogen 3.237 N/A ILE 113.A N THR 109.A O no hydrogen 3.380 N/A TYR 114.A N LYS 110.A O no hydrogen 3.344 N/A VAL 115.A N GLN 111.A O no hydrogen 2.965 N/A CYS 116.A N SER 112.A O no hydrogen 2.978 N/A CYS 116.A SG SER 112.A O no hydrogen 3.212 N/A CYS 117.A N ILE 113.A O no hydrogen 2.973 N/A CYS 117.A SG ILE 113.A O no hydrogen 3.174 N/A ILE 118.A N TYR 114.A O no hydrogen 2.783 N/A VAL 119.A N VAL 115.A O no hydrogen 2.867 N/A TRP 120.A N CYS 116.A O no hydrogen 3.110 N/A MET 121.A N CYS 117.A O no hydrogen 3.018 N/A LEU 122.A N ILE 118.A O no hydrogen 2.663 N/A ALA 123.A N VAL 119.A O no hydrogen 2.782 N/A LEU 124.A N TRP 120.A O no hydrogen 2.862 N/A GLY 125.A N MET 121.A O no hydrogen 3.083 N/A GLY 126.A N LEU 122.A O no hydrogen 3.376 N/A PHE 127.A N ALA 123.A O no hydrogen 2.911 N/A LEU 128.A N LEU 124.A O no hydrogen 2.925 N/A THR 129.A N GLY 125.A O no hydrogen 2.761 N/A THR 129.A OG1 GLY 125.A O no hydrogen 2.723 N/A MET 130.A N GLY 126.A O no hydrogen 2.894 N/A ILE 131.A N PHE 127.A O no hydrogen 3.136 N/A ILE 132.A N LEU 128.A O no hydrogen 2.767 N/A LEU 133.A N THR 129.A O no hydrogen 2.835 N/A THR 134.A N MET 130.A O no hydrogen 2.861 N/A THR 134.A OG1 MET 130.A O no hydrogen 2.841 N/A THR 134.A OG1 GLU 157.A OE1 no hydrogen 3.465 N/A THR 134.A OG1 GLU 157.A OE2 no hydrogen 3.294 N/A LEU 135.A N ILE 131.A O no hydrogen 3.050 N/A LYS 136.A N ILE 132.A O no hydrogen 3.017 N/A LYS 137.A N LEU 133.A O no hydrogen 3.309 N/A HIS 140.A NE2 THR 134.A O no hydrogen 2.357 N/A THR 143.A N ASN 141.A OD1 no hydrogen 3.017 N/A MET 144.A N ASN 141.A OD1 no hydrogen 3.355 N/A LYS 151.A NZ GLU 157.A OE2 no hydrogen 2.998 N/A ALA 158.A N ALA 154.A O no hydrogen 3.301 N/A ILE 159.A N LYS 155.A O no hydrogen 2.819 N/A PHE 160.A N GLY 156.A O no hydrogen 3.238 N/A ASN 161.A N GLU 157.A O no hydrogen 3.109 N/A PHE 162.A N ALA 158.A O no hydrogen 2.854 N/A ILE 163.A N ILE 159.A O no hydrogen 2.894 N/A LEU 164.A N PHE 160.A O no hydrogen 3.250 N/A VAL 165.A N ASN 161.A O no hydrogen 3.386 N/A VAL 166.A N PHE 162.A O no hydrogen 3.049 N/A MET 167.A N ILE 163.A O no hydrogen 2.818 N/A PHE 168.A N LEU 164.A O no hydrogen 2.988 N/A PHE 168.A N VAL 165.A O no hydrogen 3.184 N/A TRP 169.A N VAL 165.A O no hydrogen 3.415 N/A LEU 170.A N VAL 166.A O no hydrogen 3.311 N/A ILE 171.A N MET 167.A O no hydrogen 2.877 N/A PHE 172.A N PHE 168.A O no hydrogen 2.482 N/A LEU 173.A N TRP 169.A O no hydrogen 2.796 N/A LEU 174.A N LEU 170.A O no hydrogen 3.373 N/A ILE 175.A N ILE 171.A O no hydrogen 3.088 N/A ILE 176.A N PHE 172.A O no hydrogen 3.011 N/A LEU 177.A N LEU 173.A O no hydrogen 2.872 N/A SER 178.A N LEU 174.A O no hydrogen 2.803 N/A SER 178.A OG LEU 174.A O no hydrogen 2.902 N/A SER 178.A OG ILE 175.A O no hydrogen 3.062 N/A TYR 179.A N ILE 175.A O no hydrogen 2.993 N/A ILE 180.A N ILE 176.A O no hydrogen 3.217 N/A LYS 181.A N LEU 177.A O no hydrogen 3.426 N/A ILE 182.A N SER 178.A O no hydrogen 2.771 N/A GLY 183.A N TYR 179.A O no hydrogen 2.807 N/A LYS 184.A N ILE 180.A O no hydrogen 2.871 N/A ASN 185.A N LYS 181.A O no hydrogen 2.865 N/A ASN 185.A ND2 ASN 107.A OD1 no hydrogen 2.681 N/A LEU 186.A N ILE 182.A O no hydrogen 3.070 N/A LEU 187.A N GLY 183.A O no hydrogen 3.054 N/A ARG 188.A N LYS 184.A O no hydrogen 3.125 N/A ILE 189.A N ASN 185.A O no hydrogen 3.193 N/A SER 190.A N LEU 186.A O no hydrogen 2.951 N/A SER 190.A OG SER 199.A O no hydrogen 3.246 N/A LYS 191.A N LEU 187.A O no hydrogen 3.279 N/A ARG 192.A N ARG 188.A O no hydrogen 3.197 N/A ARG 193.A N ILE 189.A O no hydrogen 2.855 N/A SER 194.A OG SER 190.A O no hydrogen 2.779 N/A SER 194.A OG LYS 191.A O no hydrogen 2.938 N/A ALA 203.A N GLY 200.A O no hydrogen 3.093 N/A THR 204.A N GLY 200.A O no hydrogen 2.797 N/A THR 204.A OG1 GLY 200.A O no hydrogen 3.162 N/A THR 205.A N LYS 201.A O no hydrogen 2.865 N/A THR 205.A OG1 LYS 201.A O no hydrogen 2.702 N/A ALA 206.A N TYR 202.A O no hydrogen 3.408 N/A ARG 207.A N ALA 203.A O no hydrogen 3.184 N/A ASN 208.A N THR 204.A O no hydrogen 2.770 N/A SER 209.A N THR 205.A O no hydrogen 2.936 N/A SER 209.A OG THR 205.A O no hydrogen 3.529 N/A SER 209.A OG ALA 206.A O no hydrogen 2.772 N/A PHE 210.A N ALA 206.A O no hydrogen 3.364 N/A ILE 211.A N ARG 207.A O no hydrogen 3.120 N/A VAL 212.A N ASN 208.A O no hydrogen 3.263 N/A LEU 213.A N SER 209.A O no hydrogen 3.284 N/A ILE 214.A N PHE 210.A O no hydrogen 2.922 N/A ILE 215.A N ILE 211.A O no hydrogen 2.862 N/A PHE 216.A N VAL 212.A O no hydrogen 3.055 N/A THR 217.A N LEU 213.A O no hydrogen 2.870 N/A THR 217.A OG1 LEU 213.A O no hydrogen 2.809 N/A ILE 218.A N ILE 214.A O no hydrogen 2.753 N/A CYS 219.A N ILE 215.A O no hydrogen 3.058 N/A CYS 219.A SG ILE 215.A O no hydrogen 3.223 N/A PHE 220.A N PHE 216.A O no hydrogen 3.070 N/A VAL 221.A N THR 217.A O no hydrogen 3.091 N/A HIS 224.A N PHE 220.A O no hydrogen 3.277 N/A HIS 224.A ND1 PHE 220.A O no hydrogen 3.080 N/A ALA 225.A N VAL 221.A O no hydrogen 2.817 N/A PHE 226.A N PRO 222.A O no hydrogen 3.236 N/A ARG 227.A NE ASN 161.A OD1 no hydrogen 3.574 N/A ARG 227.A NH1 ASN 250.A OD1 no hydrogen 3.167 N/A TYR 230.A N PHE 226.A O no hydrogen 3.084 N/A ILE 231.A N ARG 227.A O no hydrogen 2.837 N/A SER 232.A N PHE 228.A O no hydrogen 3.009 N/A SER 232.A OG PHE 228.A O no hydrogen 2.936 N/A SER 233.A N ILE 229.A O no hydrogen 2.813 N/A SER 233.A OG TYR 148.A OH no hydrogen 2.525 N/A GLN 234.A N TYR 230.A O no hydrogen 3.213 N/A LEU 235.A N ILE 231.A O no hydrogen 3.233 N/A ASN 236.A N SER 232.A O no hydrogen 3.077 N/A TYR 241.A N SER 239.A OG no hydrogen 3.349 N/A LYS 243.A N SER 239.A O no hydrogen 3.189 N/A ILE 245.A N TYR 241.A O no hydrogen 3.410 N/A VAL 246.A N TRP 242.A O no hydrogen 3.086 N/A HIS 247.A N LYS 243.A O no hydrogen 2.873 N/A LYS 248.A N GLU 244.A O no hydrogen 2.734 N/A THR 249.A N ILE 245.A O no hydrogen 2.845 N/A THR 249.A OG1 ILE 245.A O no hydrogen 2.852 N/A ASN 250.A N VAL 246.A O no hydrogen 2.986 N/A GLU 251.A N HIS 247.A O no hydrogen 2.964 N/A ILE 252.A N LYS 248.A O no hydrogen 3.096 N/A MET 253.A N THR 249.A O no hydrogen 3.045 N/A LEU 254.A N ASN 250.A O no hydrogen 2.891 N/A VAL 255.A N ILE 252.A O no hydrogen 3.017 N/A LEU 256.A N ILE 252.A O no hydrogen 3.421 N/A SER 257.A N MET 253.A O no hydrogen 3.098 N/A SER 258.A N LEU 254.A O no hydrogen 2.910 N/A SER 258.A OG LEU 254.A O no hydrogen 2.951 N/A PHE 259.A N LEU 256.A O no hydrogen 3.142 N/A ASN 260.A N SER 257.A O no hydrogen 3.447 N/A SER 261.A N SER 258.A O no hydrogen 3.287 N/A CYS 262.A SG PHE 259.A O no hydrogen 3.163 N/A LEU 263.A N ASN 260.A O no hydrogen 3.295 N/A MET 267.A N LEU 263.A O no hydrogen 3.109 N/A TYR 268.A N ASP 264.A O no hydrogen 3.149 N/A PHE 269.A N PRO 265.A O no hydrogen 3.178 N/A LEU 270.A N VAL 266.A O no hydrogen 3.302 N/A MET 271.A N MET 267.A O no hydrogen 3.359 N/A SER 272.A N TYR 268.A O no hydrogen 3.417 N/A SER 272.A OG TYR 268.A O no hydrogen 2.630 N/A SER 273.A OG ASN 274.A OD1 no hydrogen 3.379 N/A ARG 276.A N SER 272.A O no hydrogen 3.402 N/A LYS 277.A N SER 273.A O no hydrogen 3.078 N/A ILE 278.A N ASN 274.A O no hydrogen 3.050 N/A MET 279.A N ILE 275.A O no hydrogen 2.530 N/A CYS 280.A N ARG 276.A O no hydrogen 2.801 N/A CYS 280.A SG ARG 276.A O no hydrogen 3.198 N/A GLN 281.A N LYS 277.A O no hydrogen 2.924 N/A