Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8jis_B.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ASP 3.A N GLU 1.A OE2 no hydrogen 3.312 N/A LEU 5.A N GLU 1.A O no hydrogen 2.978 N/A ARG 6.A N LEU 2.A O no hydrogen 2.923 N/A GLN 7.A N ASP 3.A O no hydrogen 2.981 N/A GLU 8.A N GLN 4.A O no hydrogen 2.966 N/A ALA 9.A N LEU 5.A O no hydrogen 3.077 N/A GLU 10.A N ARG 6.A O no hydrogen 2.985 N/A GLN 11.A N GLN 7.A O no hydrogen 3.215 N/A LEU 12.A N GLU 8.A O no hydrogen 3.000 N/A LYS 13.A N ALA 9.A O no hydrogen 2.941 N/A LYS 13.A NZ ALA 9.A O no hydrogen 3.166 N/A ASN 14.A N GLU 10.A O no hydrogen 2.919 N/A ASN 14.A ND2 GLU 10.A OE2 no hydrogen 3.171 N/A ASN 14.A ND2 GLN 11.A OE1 no hydrogen 3.619 N/A GLN 15.A N GLN 11.A O no hydrogen 2.932 N/A ILE 16.A N LEU 12.A O no hydrogen 2.983 N/A ARG 17.A N LYS 13.A O no hydrogen 2.875 N/A ASP 18.A N ASN 14.A O no hydrogen 2.745 N/A ALA 19.A N GLN 15.A O no hydrogen 2.805 N/A ARG 20.A N ILE 16.A O no hydrogen 2.853 N/A ARG 20.A NE ASP 256.A O no hydrogen 2.682 N/A ARG 20.A NE ASP 256.A OD2 no hydrogen 3.199 N/A ARG 20.A NH2 THR 219.A O no hydrogen 2.938 N/A ARG 20.A NH2 ASP 256.A OD2 no hydrogen 3.216 N/A LYS 21.A N ARG 17.A O no hydrogen 2.839 N/A ALA 22.A N ASP 18.A O no hydrogen 2.996 N/A CYS 23.A N ARG 20.A O no hydrogen 3.216 N/A CYS 23.A SG ALA 19.A O no hydrogen 3.453 N/A ASP 25.A N CYS 23.A O no hydrogen 2.829 N/A ALA 26.A N ASP 25.A OD1 no hydrogen 2.892 N/A THR 27.A N GLN 30.A OE1 no hydrogen 3.430 N/A ILE 31.A N THR 27.A O no hydrogen 3.083 N/A THR 32.A N LEU 28.A O no hydrogen 2.929 N/A THR 32.A OG1 LEU 28.A O no hydrogen 2.622 N/A THR 32.A OG1 SER 29.A O no hydrogen 2.999 N/A THR 32.A OG1 LEU 298.A O no hydrogen 3.240 N/A ASN 33.A N GLN 30.A O no hydrogen 3.286 N/A ASN 33.A ND2 GLN 30.A O no hydrogen 3.327 N/A ILE 41.A N ALA 303.A O no hydrogen 2.706 N/A ARG 46.A N ILE 336.A O no hydrogen 2.775 N/A ARG 47.A N ILE 336.A O no hydrogen 3.425 N/A ARG 47.A NE SER 82.A O no hydrogen 3.273 N/A ARG 47.A NE TYR 83.A O no hydrogen 3.300 N/A ARG 47.A NH2 TYR 83.A O no hydrogen 2.664 N/A LEU 49.A N LEU 334.A O no hydrogen 2.835 N/A HIS 52.A NE2 SER 70.A OG no hydrogen 2.753 N/A LEU 53.A N ASP 74.A OD2 no hydrogen 3.135 N/A ILE 56.A N SER 329.A O no hydrogen 3.191 N/A TYR 57.A N ALA 71.A O no hydrogen 2.854 N/A ALA 58.A N ALA 71.A O no hydrogen 3.502 N/A HIS 60.A N VAL 69.A O no hydrogen 3.052 N/A TRP 61.A NE1 GLY 317.A O no hydrogen 2.775 N/A GLY 62.A N LEU 67.A O no hydrogen 2.685 N/A THR 63.A OG1 PRO 105.A O no hydrogen 2.698 N/A SER 65.A N GLY 62.A O no hydrogen 3.350 N/A ARG 66.A N ASP 64.A OD1 no hydrogen 3.375 N/A ARG 66.A NE ASP 81.A OD1 no hydrogen 2.880 N/A ARG 66.A NE ASP 81.A OD2 no hydrogen 3.190 N/A ARG 66.A NH2 ASP 81.A OD1 no hydrogen 3.532 N/A LEU 67.A N ASP 64.A OD1 no hydrogen 3.375 N/A LEU 68.A N TRP 80.A O no hydrogen 3.239 N/A VAL 69.A N HIS 60.A O no hydrogen 2.899 N/A SER 70.A N ILE 78.A O no hydrogen 3.127 N/A SER 70.A OG HIS 52.A NE2 no hydrogen 2.753 N/A SER 70.A OG ILE 78.A O no hydrogen 3.375 N/A ALA 71.A N ALA 58.A O no hydrogen 2.904 N/A SER 72.A N LYS 76.A O no hydrogen 3.435 N/A SER 72.A OG ALA 54.A O no hydrogen 3.290 N/A SER 72.A OG LYS 55.A O no hydrogen 3.319 N/A SER 72.A OG ASP 74.A OD1 no hydrogen 2.615 N/A GLN 73.A N LYS 55.A O no hydrogen 2.942 N/A ASP 74.A N SER 72.A OG no hydrogen 3.208 N/A GLY 75.A N SER 72.A O no hydrogen 3.094 N/A LEU 77.A N ILE 91.A O no hydrogen 2.900 N/A ILE 78.A N SER 70.A O no hydrogen 3.382 N/A ILE 79.A N HIS 89.A O no hydrogen 3.032 N/A TRP 80.A N LEU 68.A O no hydrogen 2.822 N/A TRP 80.A NE1 SER 70.A OG no hydrogen 2.746 N/A ASP 81.A N ASN 86.A O no hydrogen 2.939 N/A SER 82.A N ARG 66.A O no hydrogen 3.215 N/A SER 82.A OG ARG 66.A O no hydrogen 2.627 N/A THR 84.A N ASP 81.A O no hydrogen 2.964 N/A THR 85.A OG1 THR 84.A O no hydrogen 2.484 N/A ASN 86.A N ASP 81.A O no hydrogen 3.366 N/A LYS 87.A NZ ARG 50.A O no hydrogen 3.042 N/A VAL 88.A N ILE 79.A O no hydrogen 2.862 N/A ILE 91.A N LEU 77.A O no hydrogen 2.656 N/A LEU 93.A N GLY 75.A O no hydrogen 3.045 N/A ARG 94.A NH2 GLU 136.A OE1 no hydrogen 3.531 N/A VAL 98.A N SER 96.A O no hydrogen 2.985 N/A MET 99.A N GLY 113.A O no hydrogen 2.800 N/A THR 100.A N GLY 113.A O no hydrogen 3.160 N/A CYS 101.A SG VAL 69.A O no hydrogen 3.999 N/A ALA 102.A N ALA 111.A O no hydrogen 3.060 N/A TYR 103.A N HIS 60.A ND1 no hydrogen 3.062 N/A ALA 104.A N TYR 109.A O no hydrogen 2.908 N/A SER 106.A OG ASP 152.A OD1 no hydrogen 2.778 N/A SER 106.A OG ASP 152.A OD2 no hydrogen 3.325 N/A GLY 107.A N ALA 104.A O no hydrogen 2.944 N/A ASN 108.A N SER 106.A OG no hydrogen 3.325 N/A VAL 110.A N TYR 122.A O no hydrogen 3.222 N/A ALA 111.A N ALA 102.A O no hydrogen 3.099 N/A CYS 112.A N SER 120.A O no hydrogen 3.198 N/A GLY 113.A N THR 100.A O no hydrogen 3.154 N/A LEU 115.A N TRP 97.A O no hydrogen 3.030 N/A ASN 117.A N GLY 114.A O no hydrogen 3.047 N/A CYS 119.A N LEU 137.A O no hydrogen 3.283 N/A CYS 119.A SG CYS 112.A O no hydrogen 3.767 N/A SER 120.A N CYS 112.A O no hydrogen 2.879 N/A SER 120.A OG GLU 136.A OE2 no hydrogen 2.917 N/A ILE 121.A N ARG 135.A O no hydrogen 2.940 N/A TYR 122.A N VAL 110.A O no hydrogen 2.986 N/A LEU 124.A N ASN 108.A O no hydrogen 3.004 N/A THR 126.A OG1 GLU 128.A OE2 no hydrogen 3.490 N/A THR 126.A OG1 ASN 130.A O no hydrogen 3.165 N/A GLY 129.A N THR 126.A O no hydrogen 3.413 N/A ASN 130.A N THR 126.A OG1 no hydrogen 2.786 N/A SER 134.A N ILE 121.A O no hydrogen 2.562 N/A ARG 135.A N ILE 121.A O no hydrogen 3.411 N/A ARG 135.A NH1 GLU 170.A O no hydrogen 3.210 N/A ARG 135.A NH2 GLU 170.A O no hydrogen 3.411 N/A LEU 137.A N CYS 119.A O no hydrogen 2.869 N/A HIS 140.A NE2 THR 157.A OG1 no hydrogen 2.899 N/A THR 141.A N ASP 161.A OD2 no hydrogen 3.135 N/A THR 141.A OG1 ASP 161.A OD2 no hydrogen 3.029 N/A LEU 144.A N GLY 114.A O no hydrogen 3.097 N/A SER 145.A N SER 158.A O no hydrogen 3.014 N/A SER 145.A OG SER 158.A OG no hydrogen 2.731 N/A SER 145.A OG VAL 185.A O no hydrogen 2.673 N/A SER 145.A OG MET 186.A O no hydrogen 3.003 N/A CYS 146.A SG LEU 188.A O no hydrogen 3.929 N/A CYS 147.A N THR 100.A OG1 no hydrogen 3.115 N/A CYS 147.A SG THR 100.A OG1 no hydrogen 3.302 N/A ARG 148.A N VAL 156.A O no hydrogen 3.073 N/A ARG 148.A NH1 CYS 101.A O no hydrogen 2.884 N/A ARG 148.A NH1 CYS 147.A O no hydrogen 2.919 N/A LEU 150.A N GLN 154.A O no hydrogen 3.063 N/A ASP 151.A N GLN 154.A O no hydrogen 3.413 N/A ASN 153.A N ASP 151.A OD1 no hydrogen 2.497 N/A GLN 154.A NE2 ASP 151.A OD2 no hydrogen 3.444 N/A VAL 156.A N ARG 148.A O no hydrogen 3.282 N/A THR 157.A N ALA 165.A O no hydrogen 2.973 N/A THR 157.A OG1 HIS 140.A NE2 no hydrogen 2.899 N/A SER 158.A N CYS 146.A O no hydrogen 2.868 N/A SER 158.A OG SER 145.A OG no hydrogen 2.731 N/A SER 158.A OG CYS 146.A O no hydrogen 3.300 N/A SER 159.A N THR 163.A O no hydrogen 3.321 N/A SER 159.A OG ASP 161.A OD1 no hydrogen 2.714 N/A SER 159.A OG THR 163.A O no hydrogen 2.835 N/A THR 162.A OG1 ASP 161.A O no hydrogen 2.488 N/A THR 162.A OG1 HIS 181.A O no hydrogen 3.375 N/A THR 163.A N ASP 161.A OD1 no hydrogen 3.237 N/A THR 163.A OG1 ASP 161.A OD1 no hydrogen 2.675 N/A CYS 164.A N PHE 178.A O no hydrogen 3.100 N/A ALA 165.A N THR 157.A O no hydrogen 3.103 N/A LEU 166.A N THR 176.A O no hydrogen 2.843 N/A TRP 167.A N ILE 155.A O no hydrogen 2.884 N/A TRP 167.A NE1 THR 157.A OG1 no hydrogen 2.827 N/A ASP 168.A N GLN 173.A O no hydrogen 2.966 N/A ILE 169.A N ASN 153.A O no hydrogen 2.746 N/A GLU 170.A N ASN 153.A OD1 no hydrogen 3.104 N/A THR 171.A N ASP 168.A OD1 no hydrogen 3.019 N/A THR 171.A OG1 ASP 168.A OD1 no hydrogen 2.966 N/A GLY 172.A N ASP 168.A O no hydrogen 2.773 N/A THR 175.A N LEU 166.A O no hydrogen 2.809 N/A THR 175.A OG1 LEU 166.A O no hydrogen 3.027 N/A PHE 178.A N CYS 164.A O no hydrogen 2.503 N/A HIS 181.A NE2 SER 199.A OG no hydrogen 2.800 N/A THR 182.A N ASP 203.A OD2 no hydrogen 3.305 N/A VAL 185.A N SER 159.A O no hydrogen 3.298 N/A MET 186.A N GLY 200.A O no hydrogen 2.865 N/A SER 187.A OG ILE 230.A O no hydrogen 3.548 N/A SER 189.A N VAL 198.A O no hydrogen 3.394 N/A SER 189.A OG LEU 190.A O no hydrogen 3.387 N/A ALA 191.A N LEU 196.A O no hydrogen 2.989 N/A THR 194.A N ALA 191.A O no hydrogen 3.024 N/A THR 194.A OG1 PRO 192.A O no hydrogen 3.143 N/A ARG 195.A N ASP 193.A OD1 no hydrogen 3.436 N/A PHE 197.A N TRP 209.A O no hydrogen 3.475 N/A VAL 198.A N SER 189.A O no hydrogen 3.432 N/A SER 199.A N LYS 207.A O no hydrogen 3.080 N/A SER 199.A OG HIS 181.A NE2 no hydrogen 2.800 N/A GLY 200.A N SER 187.A O no hydrogen 3.212 N/A ALA 201.A N SER 205.A O no hydrogen 3.477 N/A CYS 202.A SG ASP 184.A O no hydrogen 3.463 N/A CYS 202.A SG ASP 184.A OD1 no hydrogen 3.553 N/A SER 205.A N ASP 203.A OD1 no hydrogen 3.200 N/A SER 205.A OG ASP 203.A OD1 no hydrogen 2.942 N/A ALA 206.A N PHE 220.A O no hydrogen 2.876 N/A LYS 207.A N SER 199.A O no hydrogen 3.184 N/A LEU 208.A N GLN 218.A O no hydrogen 2.989 N/A TRP 209.A N PHE 197.A O no hydrogen 2.946 N/A TRP 209.A NE1 SER 199.A OG no hydrogen 2.783 N/A ARG 212.A N ASP 210.A OD1 no hydrogen 3.188 N/A GLU 213.A N ASP 210.A O no hydrogen 2.993 N/A CYS 216.A SG LEU 208.A O no hydrogen 3.783 N/A CYS 216.A SG GLN 218.A O no hydrogen 3.220 N/A CYS 216.A SG THR 219.A OG1 no hydrogen 3.429 N/A ARG 217.A N LEU 208.A O no hydrogen 2.847 N/A PHE 220.A N ALA 206.A O no hydrogen 2.728 N/A HIS 223.A ND1 ASP 245.A OD2 no hydrogen 2.989 N/A HIS 223.A NE2 THR 241.A OG1 no hydrogen 2.691 N/A GLU 224.A N ASP 245.A OD2 no hydrogen 2.973 N/A SER 225.A OG ASP 226.A OD2 no hydrogen 2.945 N/A ASP 226.A N SER 225.A OG no hydrogen 2.561 N/A ILE 227.A N ALA 201.A O no hydrogen 3.073 N/A ASN 228.A N GLY 242.A O no hydrogen 2.785 N/A ASN 228.A ND2 ASP 244.A OD1 no hydrogen 2.946 N/A ASN 228.A ND2 ILE 271.A O no hydrogen 2.939 N/A ALA 229.A N GLY 242.A O no hydrogen 3.226 N/A PHE 233.A N ALA 238.A O no hydrogen 2.951 N/A GLY 236.A N PHE 233.A O no hydrogen 2.815 N/A ASN 237.A N ASN 235.A OD1 no hydrogen 2.734 N/A THR 241.A N ARG 249.A O no hydrogen 2.994 N/A THR 241.A OG1 HIS 223.A NE2 no hydrogen 2.691 N/A THR 241.A OG1 ARG 249.A O no hydrogen 3.551 N/A GLY 242.A N ALA 229.A O no hydrogen 3.228 N/A ASP 244.A N ASP 226.A O no hydrogen 3.134 N/A THR 247.A N ASP 245.A OD1 no hydrogen 3.247 N/A CYS 248.A N TYR 262.A O no hydrogen 3.006 N/A CYS 248.A SG THR 241.A O no hydrogen 3.831 N/A ARG 249.A N THR 241.A O no hydrogen 3.132 N/A ARG 249.A NH1 HIS 223.A ND1 no hydrogen 3.180 N/A PHE 251.A N PHE 239.A O no hydrogen 2.948 N/A ASP 256.A N ASP 252.A O no hydrogen 2.615 N/A ASP 256.A N LEU 253.A O no hydrogen 3.248 N/A GLN 257.A NE2 ARG 20.A O no hydrogen 3.238 N/A GLN 257.A NE2 ALA 255.A O no hydrogen 2.939 N/A LEU 259.A N LEU 250.A O no hydrogen 2.870 N/A TYR 262.A N CYS 248.A O no hydrogen 2.670 N/A TYR 262.A OH ALA 297.A O no hydrogen 2.736 N/A ASN 266.A N HIS 264.A ND1 no hydrogen 3.321 N/A ILE 267.A N HIS 264.A O no hydrogen 3.213 N/A ILE 271.A N SER 243.A O no hydrogen 2.987 N/A THR 272.A N GLY 286.A O no hydrogen 3.167 N/A THR 272.A OG1 SER 273.A OG no hydrogen 3.080 N/A THR 272.A OG1 VAL 313.A O no hydrogen 2.590 N/A SER 273.A OG THR 272.A OG1 no hydrogen 3.080 N/A SER 273.A OG SER 314.A O no hydrogen 3.275 N/A SER 275.A N LEU 284.A O no hydrogen 2.822 N/A SER 277.A OG LEU 282.A O no hydrogen 2.552 N/A ARG 281.A NE ASP 296.A OD1 no hydrogen 2.832 N/A ARG 281.A NH2 ASP 36.A O no hydrogen 3.333 N/A ARG 281.A NH2 ASP 296.A OD1 no hydrogen 3.196 N/A ARG 281.A NH2 ASP 296.A OD2 no hydrogen 3.166 N/A LEU 282.A N SER 277.A OG no hydrogen 2.612 N/A LEU 283.A N TRP 295.A O no hydrogen 2.656 N/A LEU 284.A N SER 275.A O no hydrogen 2.845 N/A ALA 285.A N ASN 293.A O no hydrogen 3.080 N/A TYR 287.A N ASN 291.A O no hydrogen 3.016 N/A ASP 288.A N GLY 270.A O no hydrogen 3.417 N/A VAL 294.A N GLY 304.A O no hydrogen 2.942 N/A TRP 295.A N LEU 283.A O no hydrogen 2.547 N/A TRP 295.A NE1 TYR 287.A OH no hydrogen 2.883 N/A ASP 296.A N ASP 301.A O no hydrogen 3.289 N/A ALA 297.A N ARG 281.A O no hydrogen 3.174 N/A LEU 298.A N ASP 296.A OD1 no hydrogen 3.427 N/A ALA 300.A N ASP 296.A O no hydrogen 2.993 N/A ALA 303.A N VAL 294.A O no hydrogen 3.095 N/A LEU 306.A N CYS 292.A O no hydrogen 2.867 N/A HIS 309.A NE2 THR 327.A OG1 no hydrogen 2.880 N/A ASP 310.A N ASP 331.A OD2 no hydrogen 3.065 N/A ARG 312.A N ASN 311.A OD1 no hydrogen 2.830 N/A SER 314.A N GLY 328.A O no hydrogen 3.162 N/A SER 314.A OG ILE 56.A O no hydrogen 2.750 N/A GLY 317.A N ALA 326.A O no hydrogen 3.069 N/A THR 319.A N ALA 324.A O no hydrogen 3.096 N/A THR 319.A OG1 ASP 321.A OD1 no hydrogen 2.905 N/A THR 319.A OG1 ALA 324.A O no hydrogen 3.153 N/A ASP 320.A N SER 65.A OG no hydrogen 3.039 N/A MET 323.A N ASP 321.A OD1 no hydrogen 2.979 N/A ALA 324.A N THR 319.A OG1 no hydrogen 2.942 N/A VAL 325.A N TRP 337.A O no hydrogen 3.303 N/A ALA 326.A N GLY 317.A O no hydrogen 3.023 N/A THR 327.A N LYS 335.A O no hydrogen 3.020 N/A THR 327.A OG1 HIS 309.A NE2 no hydrogen 2.880 N/A GLY 328.A N CYS 315.A O no hydrogen 3.104 N/A SER 329.A OG ARG 312.A O no hydrogen 2.744 N/A TRP 330.A N ARG 312.A O no hydrogen 2.841 N/A SER 332.A N SER 329.A O no hydrogen 3.187 N/A SER 332.A OG HIS 52.A O no hydrogen 3.174 N/A SER 332.A OG ASP 331.A O no hydrogen 2.707 N/A PHE 333.A N ASP 331.A OD1 no hydrogen 3.094 N/A LEU 334.A N LEU 49.A O no hydrogen 3.068 N/A LYS 335.A N THR 327.A O no hydrogen 3.101 N/A ILE 336.A N ARG 47.A O no hydrogen 2.846 N/A TRP 337.A N VAL 325.A O no hydrogen 2.816 N/A TRP 337.A NE1 THR 327.A OG1 no hydrogen 3.077 N/A ASN 338.A N ARG 44.A O no hydrogen 3.428 N/A ASN 338.A ND2 MET 323.A O no hydrogen 2.986 N/A