Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8jlg_B.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): SER 2.A OG LEU 4.A O no hydrogen 3.429 N/A SER 2.A OG LEU 199.A O no hydrogen 3.396 N/A ILE 3.A N LEU 199.A O no hydrogen 2.977 N/A SER 5.A N ASP 15.A OD1 no hydrogen 2.633 N/A SER 5.A OG SER 5.A O no hydrogen 2.398 N/A SER 5.A OG ASP 15.A OD1 no hydrogen 3.569 N/A ILE 6.A N PHE 197.A O no hydrogen 3.012 N/A VAL 7.A N ILE 14.A O no hydrogen 3.040 N/A LYS 9.A N ASP 12.A O no hydrogen 2.991 N/A ILE 14.A N VAL 7.A O no hydrogen 3.009 N/A LEU 16.A N SER 5.A O no hydrogen 3.160 N/A LEU 16.A N SER 5.A OG no hydrogen 3.290 N/A SER 17.A N ASP 15.A OD1 no hydrogen 3.405 N/A SER 17.A OG ILE 3.A O no hydrogen 2.387 N/A SER 17.A OG ASP 15.A OD1 no hydrogen 3.299 N/A SER 17.A OG ASP 15.A OD2 no hydrogen 2.588 N/A LYS 22.A NZ ILE 23.A O no hydrogen 3.186 N/A LYS 22.A NZ ASN 24.A OD1 no hydrogen 2.868 N/A ASN 24.A N GLU 50.A O no hydrogen 2.405 N/A GLY 26.A N THR 48.A O no hydrogen 2.588 N/A ARG 28.A NE SER 46.A OG no hydrogen 3.111 N/A TYR 30.A N LYS 40.A O no hydrogen 3.355 N/A SER 33.A N ASP 32.A OD1 no hydrogen 2.397 N/A LYS 36.A NZ TYR 8.A OH no hydrogen 2.953 N/A GLN 38.A N ASP 35.A O no hydrogen 2.824 N/A GLN 38.A NE2 ASN 228.A OD1 no hydrogen 3.441 N/A ILE 39.A N ILE 194.A O no hydrogen 2.807 N/A LYS 40.A N TYR 30.A O no hydrogen 3.284 N/A LEU 41.A N ILE 192.A O no hydrogen 2.954 N/A ILE 42.A N SER 47.A OG no hydrogen 2.990 N/A ASN 43.A ND2 CYS 185.A O no hydrogen 3.233 N/A ASN 43.A ND2 ASP 187.A O no hydrogen 2.304 N/A LEU 44.A N ILE 42.A O no hydrogen 3.001 N/A SER 47.A OG ILE 42.A O no hydrogen 3.410 N/A THR 48.A OG1 GLU 45.A O no hydrogen 3.064 N/A ILE 49.A N PHE 180.A O no hydrogen 3.346 N/A GLU 50.A N ASN 24.A O no hydrogen 2.499 N/A VAL 51.A N ILE 178.A O no hydrogen 3.230 N/A ILE 52.A N LYS 22.A O no hydrogen 2.741 N/A LEU 53.A N ASN 176.A O no hydrogen 3.215 N/A ILE 57.A N LYS 54.A O no hydrogen 3.344 N/A TYR 59.A OH GLU 64.A O no hydrogen 2.330 N/A SER 67.A N PHE 200.A O no hydrogen 2.904 N/A SER 67.A OG ILE 144.A O no hydrogen 2.619 N/A THR 68.A N ILE 144.A O no hydrogen 3.021 N/A THR 68.A OG1 ASN 198.A O no hydrogen 3.057 N/A SER 69.A N ASN 198.A O no hydrogen 3.051 N/A SER 69.A OG ASN 198.A OD1 no hydrogen 3.488 N/A PHE 70.A N VAL 142.A O no hydrogen 2.797 N/A TRP 71.A N LYS 195.A O no hydrogen 2.961 N/A TRP 71.A NE1 GLN 216.A OE1 no hydrogen 2.984 N/A ILE 72.A N ILE 140.A O no hydrogen 2.918 N/A LYS 73.A N MET 193.A O no hydrogen 2.891 N/A LYS 73.A NZ ASP 413.A OD2 no hydrogen 3.072 N/A LYS 76.A N GLY 415.A O no hydrogen 3.069 N/A LYS 76.A NZ TRP 416.A O no hydrogen 3.336 N/A TYR 77.A OH TYR 87.A OH no hydrogen 2.789 N/A ASN 82.A N SER 79.A O no hydrogen 3.484 N/A ASN 82.A ND2 ASP 187.A OD2 no hydrogen 2.614 N/A ASN 85.A ND2 GLY 184.A O no hydrogen 2.919 N/A TYR 87.A N LEU 103.A O no hydrogen 2.846 N/A TYR 87.A OH TYR 77.A OH no hydrogen 2.789 N/A THR 88.A N ASP 183.A O no hydrogen 3.050 N/A ILE 89.A N VAL 101.A O no hydrogen 2.950 N/A ILE 90.A N VAL 101.A O no hydrogen 3.097 N/A ASN 91.A N MET 179.A O no hydrogen 2.762 N/A CYS 92.A N TRP 99.A O no hydrogen 2.947 N/A CYS 92.A SG SER 175.A O no hydrogen 3.666 N/A CYS 92.A SG LYS 177.A O no hydrogen 3.981 N/A GLU 94.A N SER 97.A O no hydrogen 3.105 N/A SER 97.A OG GLN 113.A O no hydrogen 3.268 N/A SER 97.A OG HIS 173.A O no hydrogen 3.549 N/A GLY 98.A N GLN 113.A O no hydrogen 3.249 N/A LYS 100.A N THR 111.A O no hydrogen 3.197 N/A LYS 100.A NZ THR 88.A OG1 no hydrogen 3.161 N/A VAL 101.A N ILE 90.A O no hydrogen 2.812 N/A SER 102.A N ILE 109.A O no hydrogen 3.045 N/A SER 102.A OG GLU 86.A OE1 no hydrogen 2.786 N/A LEU 103.A N TYR 87.A O no hydrogen 2.800 N/A ASN 104.A ND2 GLU 107.A OE2 no hydrogen 3.404 N/A TYR 105.A OH ILE 273.A O no hydrogen 2.272 N/A GLU 107.A N ASN 104.A O no hydrogen 3.349 N/A ILE 108.A N PHE 124.A O no hydrogen 2.978 N/A ILE 109.A N SER 102.A O no hydrogen 2.809 N/A TRP 110.A N VAL 122.A O no hydrogen 2.808 N/A TRP 110.A NE1 ASN 146.A OD1 no hydrogen 3.157 N/A THR 111.A N LYS 100.A O no hydrogen 3.090 N/A LEU 112.A N GLN 120.A O no hydrogen 2.991 N/A GLN 113.A N GLY 98.A O no hydrogen 2.964 N/A ASN 115.A N ASN 171.A O no hydrogen 3.267 N/A LYS 116.A NZ ASN 115.A OD1 no hydrogen 3.427 N/A GLN 117.A N ASP 114.A O no hydrogen 3.082 N/A ASN 118.A N ASP 114.A OD1 no hydrogen 2.435 N/A ASN 118.A ND2 ASP 114.A OD2 no hydrogen 2.364 N/A GLN 120.A N LEU 112.A O no hydrogen 3.306 N/A VAL 122.A N TRP 110.A O no hydrogen 2.849 N/A PHE 124.A N ILE 108.A O no hydrogen 2.938 N/A TYR 126.A N GLY 106.A O no hydrogen 3.141 N/A GLN 128.A NE2 TYR 77.A O no hydrogen 2.890 N/A MET 129.A N SER 127.A OG no hydrogen 3.073 N/A TYR 135.A N SER 133.A OG no hydrogen 2.817 N/A ILE 136.A N SER 133.A OG no hydrogen 3.022 N/A ASN 137.A N ILE 74.A O no hydrogen 2.839 N/A ASN 137.A ND2 ASP 413.A OD2 no hydrogen 2.815 N/A ARG 138.A NE PHE 225.A O no hydrogen 3.096 N/A ARG 138.A NH1 SER 133.A O no hydrogen 2.773 N/A TRP 139.A N TRP 226.A O no hydrogen 3.380 N/A TRP 139.A NE1 ASN 228.A OD1 no hydrogen 2.904 N/A ILE 140.A N ILE 72.A O no hydrogen 2.883 N/A PHE 141.A N ASN 157.A OD1 no hydrogen 2.942 N/A VAL 142.A N PHE 70.A O no hydrogen 2.788 N/A THR 143.A N TYR 155.A O no hydrogen 3.062 N/A THR 143.A OG1 THR 68.A O no hydrogen 2.943 N/A ILE 144.A N THR 68.A O no hydrogen 2.864 N/A THR 145.A N LYS 153.A O no hydrogen 3.180 N/A ASN 146.A N PHE 66.A O no hydrogen 3.079 N/A ASN 146.A ND2 PHE 66.A O no hydrogen 3.653 N/A ASN 147.A N LYS 151.A O no hydrogen 3.191 N/A ASN 147.A ND2 ASN 65.A OD1 no hydrogen 2.832 N/A ARG 148.A N ASN 65.A OD1 no hydrogen 3.193 N/A ARG 148.A NH1 TYR 59.A OH no hydrogen 2.573 N/A THR 150.A OG1 ASN 147.A OD1 no hydrogen 2.684 N/A SER 152.A N LYS 164.A O no hydrogen 3.042 N/A SER 152.A OG ASN 146.A OD1 no hydrogen 2.816 N/A LYS 153.A N THR 145.A O no hydrogen 2.996 N/A ILE 154.A N ASP 162.A O no hydrogen 3.027 N/A TYR 155.A N THR 143.A O no hydrogen 2.877 N/A ILE 156.A N ARG 159.A O no hydrogen 2.927 N/A ASN 157.A N PHE 141.A O no hydrogen 2.824 N/A ARG 159.A N ILE 156.A O no hydrogen 3.302 N/A ILE 161.A N ILE 154.A O no hydrogen 3.066 N/A LYS 164.A N SER 152.A O no hydrogen 2.993 N/A LYS 164.A NZ ASP 162.A OD1 no hydrogen 2.999 N/A SER 167.A OG LEU 149.A O no hydrogen 3.250 N/A SER 167.A OG THR 150.A O no hydrogen 3.312 N/A LEU 169.A N ILE 166.A O no hydrogen 3.179 N/A HIS 173.A N SER 97.A OG no hydrogen 3.164 N/A ALA 174.A N TYR 59.A O no hydrogen 3.115 N/A SER 175.A N CYS 92.A O no hydrogen 3.305 N/A SER 175.A OG GLU 94.A OE1 no hydrogen 3.367 N/A SER 175.A OG LYS 177.A O no hydrogen 3.486 N/A LYS 177.A N SER 175.A OG no hydrogen 3.145 N/A ILE 178.A N VAL 51.A O no hydrogen 2.975 N/A MET 179.A N ASN 91.A O no hydrogen 2.795 N/A PHE 180.A N ILE 49.A O no hydrogen 3.055 N/A LYS 181.A N ILE 89.A O no hydrogen 3.048 N/A LYS 181.A NZ GLU 45.A OE1 no hydrogen 2.367 N/A ASP 183.A N THR 88.A O no hydrogen 2.828 N/A CYS 185.A SG ASP 187.A O no hydrogen 3.694 N/A ARG 186.A N ASN 85.A OD1 no hydrogen 2.985 N/A ARG 186.A NH1 ILE 81.A O no hydrogen 3.062 N/A ARG 186.A NH2 LEU 83.A O no hydrogen 3.243 N/A ARG 190.A NH1 PRO 75.A O no hydrogen 3.422 N/A ARG 190.A NH2 LYS 76.A O no hydrogen 3.135 N/A ILE 192.A N LEU 41.A O no hydrogen 2.942 N/A MET 193.A N LYS 73.A O no hydrogen 3.277 N/A ILE 194.A N ILE 39.A O no hydrogen 2.893 N/A LYS 195.A N TRP 71.A O no hydrogen 2.996 N/A ASN 198.A N SER 69.A O no hydrogen 2.819 N/A LEU 199.A N LEU 4.A O no hydrogen 2.727 N/A PHE 200.A N SER 67.A O no hydrogen 2.807 N/A ASN 205.A N GLU 208.A OE1 no hydrogen 3.462 N/A GLU 208.A N ASN 205.A OD1 no hydrogen 2.840 N/A ILE 209.A N ASN 205.A O no hydrogen 3.004 N/A LYS 210.A N GLU 206.A O no hydrogen 2.911 N/A ASP 211.A N LYS 207.A O no hydrogen 2.929 N/A LEU 212.A N GLU 208.A O no hydrogen 2.894 N/A TYR 213.A N ILE 209.A O no hydrogen 2.907 N/A ASP 214.A N LYS 210.A O no hydrogen 2.946 N/A SER 215.A N ASP 211.A O no hydrogen 2.886 N/A GLN 216.A N LEU 212.A O no hydrogen 2.941 N/A GLN 216.A NE2 ASN 198.A OD1 no hydrogen 2.997 N/A SER 217.A N ASP 214.A O no hydrogen 3.232 N/A SER 217.A OG TYR 213.A O no hydrogen 2.345 N/A ASN 218.A ND2 TYR 229.A OH no hydrogen 3.100 N/A ILE 221.A N ASN 218.A O no hydrogen 3.121 N/A LEU 222.A N VAL 299.A O no hydrogen 3.307 N/A LYS 223.A NZ SER 217.A O no hydrogen 2.330 N/A ASP 224.A N ASN 228.A O no hydrogen 2.922 N/A PHE 225.A N PHE 409.A O no hydrogen 2.576 N/A TRP 226.A NE1 PRO 411.A O no hydrogen 2.983 N/A GLY 227.A N ASP 224.A O no hydrogen 3.138 N/A LEU 230.A N LEU 222.A O no hydrogen 3.306 N/A GLN 231.A N TYR 236.A OH no hydrogen 2.987 N/A TYR 232.A N ASN 297.A O no hydrogen 3.062 N/A ASP 233.A N ILE 287.A O no hydrogen 2.838 N/A TYR 237.A N ILE 410.A O no hydrogen 2.778 N/A LEU 239.A N GLU 408.A O no hydrogen 3.129 N/A ASN 240.A ND2 GLY 404.A O no hydrogen 3.522 N/A LEU 241.A N SER 406.A O no hydrogen 3.265 N/A TYR 247.A N LYS 262.A O no hydrogen 2.745 N/A ASP 249.A N TYR 260.A O no hydrogen 2.889 N/A TYR 260.A N ASP 249.A O no hydrogen 2.836 N/A LEU 261.A N ALA 384.A O no hydrogen 2.882 N/A LYS 262.A N TYR 247.A O no hydrogen 2.912 N/A ARG 265.A NE PRO 244.A O no hydrogen 3.450 N/A ARG 265.A NH1 THR 278.A O no hydrogen 3.064 N/A ARG 265.A NH2 MET 238.A O no hydrogen 3.215 N/A GLY 266.A N GLU 281.A OE1 no hydrogen 2.665 N/A VAL 268.A N ASN 276.A O no hydrogen 3.259 N/A THR 270.A N TYR 274.A O no hydrogen 2.971 N/A THR 270.A OG1 VAL 269.A O no hydrogen 3.115 N/A THR 270.A OG1 TYR 274.A OH no hydrogen 3.090 N/A ILE 273.A N THR 270.A O no hydrogen 2.731 N/A TYR 274.A N THR 270.A O no hydrogen 3.046 N/A ASN 276.A ND2 GLN 128.A O no hydrogen 3.156 N/A ASN 276.A ND2 VAL 130.A O no hydrogen 2.787 N/A SER 277.A N ASN 131.A O no hydrogen 3.049 N/A SER 277.A OG GLY 266.A O no hydrogen 2.982 N/A THR 278.A N GLY 266.A O no hydrogen 3.187 N/A THR 278.A OG1 GLU 281.A OE1 no hydrogen 2.934 N/A LEU 279.A N GLU 418.A OE1 no hydrogen 2.913 N/A THR 283.A N VAL 248.A O no hydrogen 3.087 N/A THR 283.A OG1 VAL 248.A O no hydrogen 3.199 N/A PHE 285.A N TYR 236.A O no hydrogen 2.770 N/A ILE 286.A N ASN 308.A O no hydrogen 2.737 N/A LYS 288.A N TYR 306.A O no hydrogen 3.063 N/A LYS 288.A NZ ASP 233.A OD1 no hydrogen 3.341 N/A LYS 289.A NZ ASN 294.A O no hydrogen 3.460 N/A LYS 289.A NZ ASP 296.A O no hydrogen 2.980 N/A ASN 297.A ND2 TYR 232.A O no hydrogen 3.265 N/A VAL 299.A N LEU 230.A O no hydrogen 2.724 N/A ARG 300.A N ASP 303.A OD2 no hydrogen 2.707 N/A ARG 300.A NH1 ASP 296.A OD1 no hydrogen 2.774 N/A ARG 300.A NH1 ASP 296.A OD2 no hydrogen 2.634 N/A ARG 300.A NH2 ASP 296.A OD2 no hydrogen 2.719 N/A ASN 301.A N GLY 220.A O no hydrogen 3.094 N/A ASN 302.A N MET 348.A O no hydrogen 2.765 N/A VAL 305.A N VAL 346.A O no hydrogen 2.756 N/A TYR 306.A N LYS 288.A O no hydrogen 2.941 N/A ASN 308.A N ILE 286.A O no hydrogen 2.667 N/A VAL 309.A N TYR 316.A O no hydrogen 2.973 N/A VAL 310.A N LYS 284.A O no hydrogen 3.091 N/A VAL 311.A N LYS 314.A O no hydrogen 2.969 N/A LYS 314.A N VAL 311.A O no hydrogen 3.034 N/A TYR 316.A N VAL 309.A O no hydrogen 2.960 N/A ARG 317.A N LEU 334.A O no hydrogen 2.700 N/A ARG 317.A NE ASN 308.A OD1 no hydrogen 3.075 N/A LEU 318.A N ILE 307.A O no hydrogen 2.938 N/A ALA 319.A N SER 332.A O no hydrogen 3.266 N/A THR 320.A N SER 343.A O no hydrogen 2.995 N/A GLN 324.A N ALA 322.A O no hydrogen 3.158 N/A GLN 324.A NE2 ASN 321.A O no hydrogen 2.723 N/A LYS 329.A N ALA 388.A O no hydrogen 2.851 N/A LYS 329.A NZ GLY 326.A O no hydrogen 3.417 N/A LYS 329.A NZ VAL 327.A O no hydrogen 3.434 N/A LEU 331.A N LEU 386.A O no hydrogen 2.880 N/A SER 332.A N ALA 319.A O no hydrogen 3.096 N/A SER 332.A OG ALA 319.A O no hydrogen 3.145 N/A LEU 334.A N ARG 317.A O no hydrogen 2.900 N/A ASP 338.A N GLU 335.A O no hydrogen 2.955 N/A LEU 342.A N VAL 339.A O no hydrogen 3.269 N/A SER 343.A N THR 320.A O no hydrogen 3.087 N/A SER 343.A OG GLN 365.A O no hydrogen 2.620 N/A VAL 346.A N VAL 305.A O no hydrogen 3.085 N/A VAL 347.A N ASN 363.A O no hydrogen 2.718 N/A MET 348.A N ASP 303.A O no hydrogen 3.338 N/A LYS 349.A N LYS 361.A O no hydrogen 2.948 N/A LYS 349.A NZ ASN 302.A OD1 no hydrogen 2.517 N/A SER 350.A N ASN 301.A OD1 no hydrogen 2.637 N/A SER 350.A OG SER 219.A O no hydrogen 2.715 N/A SER 350.A OG ILE 221.A O no hydrogen 3.464 N/A ASP 352.A N ILE 356.A O no hydrogen 3.027 N/A GLY 355.A N ASP 352.A O no hydrogen 3.162 N/A ARG 357.A NH1 ASP 214.A OD1 no hydrogen 2.703 N/A ASN 358.A N SER 350.A O no hydrogen 3.358 N/A LYS 359.A NZ GLU 408.A OE1 no hydrogen 3.529 N/A CYS 360.A SG LYS 223.A O no hydrogen 3.656 N/A LYS 361.A N LYS 349.A O no hydrogen 3.335 N/A LYS 361.A NZ ASP 352.A OD1 no hydrogen 3.149 N/A ASN 363.A N VAL 347.A O no hydrogen 2.884 N/A LEU 364.A N GLY 373.A O no hydrogen 3.053 N/A GLN 365.A N VAL 345.A O no hydrogen 2.660 N/A GLN 365.A NE2 ASP 371.A OD1 no hydrogen 2.390 N/A ASP 366.A N ASN 370.A O no hydrogen 3.313 N/A ASN 367.A N ASP 366.A OD1 no hydrogen 2.556 N/A ASN 367.A ND2 ASN 341.A OD1 no hydrogen 2.213 N/A GLY 369.A N ASP 366.A O no hydrogen 3.339 N/A ILE 372.A N LEU 364.A O no hydrogen 3.135 N/A ILE 375.A N MET 362.A O no hydrogen 2.790 N/A GLY 376.A N VAL 387.A O no hydrogen 2.690 N/A HIS 378.A N LYS 385.A O no hydrogen 2.921 N/A TYR 380.A N ILE 383.A O no hydrogen 2.782 N/A TYR 380.A OH GLU 328.A OE1 no hydrogen 3.024 N/A ILE 383.A N TYR 380.A O no hydrogen 2.635 N/A LYS 385.A N HIS 378.A O no hydrogen 3.108 N/A LEU 386.A N MET 259.A O no hydrogen 3.010 N/A VAL 387.A N GLY 376.A O no hydrogen 2.817 N/A ALA 388.A N LYS 329.A O no hydrogen 2.625 N/A SER 389.A N PHE 374.A O no hydrogen 3.212 N/A ASN 390.A ND2 ASP 371.A O no hydrogen 3.017 N/A TRP 391.A N SER 389.A OG no hydrogen 3.005 N/A ARG 394.A N ASN 390.A O no hydrogen 2.927 N/A GLN 395.A N TRP 391.A O no hydrogen 2.968 N/A VAL 396.A N TYR 392.A O no hydrogen 2.918 N/A GLY 397.A N ASN 393.A O no hydrogen 2.895 N/A LYS 398.A N ARG 394.A O no hydrogen 2.914 N/A ALA 399.A N VAL 396.A O no hydrogen 3.118 N/A SER 400.A N GLN 395.A O no hydrogen 2.720 N/A CYS 405.A SG THR 402.A OG1 no hydrogen 3.443 N/A TRP 407.A N CYS 360.A O no hydrogen 2.859 N/A TRP 407.A NE1 ILE 375.A O no hydrogen 3.303 N/A GLU 408.A N LEU 239.A O no hydrogen 2.818 N/A ILE 410.A N TYR 237.A O no hydrogen 2.731 N/A ASP 413.A N TYR 280.A OH no hydrogen 3.006 N/A ASP 414.A N ASP 413.A OD1 no hydrogen 3.013 N/A TRP 416.A N ASP 413.A O no hydrogen 3.496 N/A TRP 416.A NE1 GLU 418.A OE1 no hydrogen 3.179 N/A