Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8k3c_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): SER 1.A N THR 4.A OG1 no hydrogen 2.643 N/A SER 6.A N GLN 2.A O no hydrogen 3.010 N/A SER 6.A OG GLN 2.A O no hydrogen 2.931 N/A ILE 7.A N SER 3.A O no hydrogen 2.877 N/A ASN 8.A N THR 4.A O no hydrogen 2.932 N/A GLU 9.A N ALA 5.A O no hydrogen 2.881 N/A ASN 10.A N SER 6.A O no hydrogen 2.983 N/A VAL 11.A N ILE 7.A O no hydrogen 2.848 N/A ASN 12.A N ASN 8.A O no hydrogen 2.946 N/A GLU 13.A N GLU 9.A O no hydrogen 2.915 N/A LYS 14.A N ASN 10.A O no hydrogen 2.927 N/A LYS 14.A N VAL 11.A O no hydrogen 2.979 N/A CYS 15.A N VAL 11.A O no hydrogen 2.515 N/A LYS 16.A NZ ASN 12.A OD1 no hydrogen 3.033 N/A CYS 31.A SG LYS 115.A O no hydrogen 3.829 N/A GLN 43.A N ARG 41.A O no hydrogen 2.882 N/A THR 44.A OG1 ASP 126.A O no hydrogen 3.494 N/A SER 48.A N LEU 436.A O no hydrogen 2.988 N/A LEU 50.A N ASN 49.A OD1 no hydrogen 2.739 N/A CYS 58.A N PRO 467.A O no hydrogen 2.589 N/A CYS 58.A SG GLN 60.A O no hydrogen 3.435 N/A ASN 64.A N THR 62.A OG1 no hydrogen 3.270 N/A LYS 70.A N ALA 463.A O no hydrogen 2.852 N/A SER 73.A OG TYR 74.A O no hydrogen 3.342 N/A VAL 78.A N LEU 76.A O no hydrogen 3.020 N/A THR 84.A N GLN 81.A O no hydrogen 3.403 N/A CYS 85.A N ARG 105.A O no hydrogen 2.708 N/A ILE 86.A N ILE 457.A O no hydrogen 3.063 N/A THR 87.A N LEU 103.A O no hydrogen 2.804 N/A THR 87.A OG1 LEU 103.A O no hydrogen 3.422 N/A ALA 92.A N ALA 99.A O no hydrogen 3.138 N/A ASP 94.A N TYR 97.A O no hydrogen 3.164 N/A PHE 98.A N GLY 122.A O no hydrogen 3.365 N/A ALA 99.A N ALA 92.A O no hydrogen 2.758 N/A TYR 100.A N GLY 120.A O no hydrogen 2.368 N/A TYR 100.A OH TYR 74.A OH no hydrogen 2.224 N/A SER 101.A N LEU 90.A O no hydrogen 3.421 N/A HIS 102.A N ILE 118.A O no hydrogen 3.074 N/A LEU 103.A N THR 87.A O no hydrogen 2.538 N/A GLU 104.A N GLN 116.A O no hydrogen 2.488 N/A ARG 105.A N CYS 85.A O no hydrogen 2.575 N/A ARG 105.A NE SER 114.A OG no hydrogen 2.574 N/A ARG 105.A NH1 CYS 109.A O no hydrogen 2.885 N/A ARG 105.A NH2 SER 114.A OG no hydrogen 2.744 N/A ILE 106.A N VAL 113.A O no hydrogen 2.446 N/A ARG 111.A N SER 108.A OG no hydrogen 3.207 N/A LYS 115.A N GLU 104.A O no hydrogen 2.534 N/A GLN 116.A N GLU 104.A O no hydrogen 3.048 N/A GLN 116.A NE2 GLU 104.A OE1 no hydrogen 2.556 N/A ILE 118.A N HIS 102.A O no hydrogen 2.655 N/A ILE 119.A N TRP 140.A O no hydrogen 2.822 N/A GLY 120.A N TYR 100.A O no hydrogen 2.359 N/A VAL 121.A N ASN 138.A O no hydrogen 2.642 N/A GLY 122.A N PHE 98.A O no hydrogen 3.059 N/A GLU 123.A N PHE 135.A O no hydrogen 2.964 N/A VAL 124.A N GLY 96.A O no hydrogen 3.375 N/A LEU 125.A N SER 133.A O no hydrogen 3.296 N/A ASP 126.A N GLU 45.A O no hydrogen 3.369 N/A ARG 127.A N VAL 131.A O no hydrogen 2.640 N/A ARG 127.A NE ASP 129.A OD1 no hydrogen 3.023 N/A SER 133.A N LEU 125.A O no hydrogen 3.046 N/A PHE 135.A N GLU 123.A O no hydrogen 2.926 N/A THR 137.A N VAL 121.A O no hydrogen 3.043 N/A THR 137.A OG1 VAL 121.A O no hydrogen 3.130 N/A THR 137.A OG1 VAL 190.A O no hydrogen 3.048 N/A ASN 138.A N VAL 121.A O no hydrogen 2.739 N/A TRP 140.A N ILE 119.A O no hydrogen 2.704 N/A ASN 146.A N ASN 144.A OD1 no hydrogen 2.705 N/A ASN 146.A ND2 ILE 24.A O no hydrogen 3.403 N/A ASN 146.A ND2 ASN 144.A OD1 no hydrogen 3.401 N/A THR 147.A OG1 ASN 144.A O no hydrogen 3.213 N/A TYR 149.A N ALA 165.A O no hydrogen 3.060 N/A HIS 150.A NE2 ASP 171.A OD1 no hydrogen 2.718 N/A SER 152.A N LEU 163.A O no hydrogen 2.875 N/A SER 152.A OG LEU 163.A O no hydrogen 3.540 N/A VAL 154.A N TYR 161.A O no hydrogen 2.925 N/A ASN 156.A N PHE 159.A O no hydrogen 3.132 N/A ASN 156.A ND2 GLY 228.A O no hydrogen 3.456 N/A GLU 158.A N TYR 155.A OH no hydrogen 2.847 N/A TYR 160.A N LEU 188.A O no hydrogen 2.669 N/A TYR 161.A N VAL 154.A O no hydrogen 2.650 N/A VAL 162.A N THR 186.A O no hydrogen 2.787 N/A LEU 163.A N SER 152.A O no hydrogen 2.976 N/A CYS 164.A N MET 184.A O no hydrogen 2.464 N/A ALA 165.A N TYR 149.A O no hydrogen 3.012 N/A SER 167.A N THR 147.A O no hydrogen 3.169 N/A SER 167.A OG GLY 170.A O no hydrogen 2.562 N/A VAL 169.A N SER 167.A OG no hydrogen 2.918 N/A ASN 175.A N ASP 171.A O no hydrogen 2.795 N/A TRP 179.A N SER 176.A O no hydrogen 3.411 N/A TRP 179.A NE1 VAL 166.A O no hydrogen 3.244 N/A SER 182.A N SER 180.A OG no hydrogen 3.422 N/A SER 182.A OG LEU 183.A O no hydrogen 3.402 N/A MET 184.A N CYS 164.A O no hydrogen 2.555 N/A MET 185.A N LEU 204.A O no hydrogen 2.977 N/A THR 186.A N VAL 162.A O no hydrogen 2.412 N/A ARG 187.A N HIS 202.A O no hydrogen 2.419 N/A ARG 187.A NH2 GLY 198.A O no hydrogen 2.632 N/A LEU 188.A N TYR 160.A O no hydrogen 3.235 N/A ALA 189.A N ASN 200.A O no hydrogen 2.744 N/A LYS 191.A NZ GLU 123.A OE2 no hydrogen 2.450 N/A LYS 193.A N ASN 200.A OD1 no hydrogen 2.701 N/A ASN 200.A N GLY 196.A O no hydrogen 2.959 N/A ASN 200.A ND2 ASN 195.A O no hydrogen 2.931 N/A GLN 201.A N GLY 197.A O no hydrogen 2.918 N/A GLN 201.A NE2 VAL 139.A O no hydrogen 2.582 N/A HIS 202.A N ARG 187.A O no hydrogen 2.645 N/A LEU 204.A N MET 185.A O no hydrogen 2.409 N/A LYS 211.A N ILE 209.A O no hydrogen 3.065 N/A LYS 211.A NZ ASP 215.A O no hydrogen 3.062 N/A TYR 214.A N LYS 211.A O no hydrogen 3.366 N/A ASP 215.A N PHE 238.A O no hydrogen 2.680 N/A LYS 216.A N PHE 238.A O no hydrogen 3.119 N/A LYS 216.A NZ SER 176.A O no hydrogen 2.355 N/A LYS 216.A NZ TRP 179.A O no hydrogen 3.310 N/A LYS 216.A NZ TYR 276.A OH no hydrogen 3.263 N/A MET 218.A N VAL 236.A O no hydrogen 3.066 N/A TYR 220.A N PRO 234.A O no hydrogen 3.379 N/A GLY 224.A N ALA 153.A O no hydrogen 2.782 N/A ILE 225.A N TYR 232.A O no hydrogen 3.282 N/A LYS 226.A NZ GLU 95.A OE2 no hydrogen 2.965 N/A GLN 227.A N THR 230.A O no hydrogen 3.047 N/A THR 230.A N GLN 227.A O no hydrogen 3.214 N/A THR 230.A OG1 ASP 229.A OD1 no hydrogen 2.992 N/A LEU 231.A N TYR 285.A O no hydrogen 2.859 N/A TYR 232.A N ILE 225.A O no hydrogen 2.863 N/A PHE 233.A N LEU 283.A O no hydrogen 3.292 N/A ALA 235.A N GLY 281.A O no hydrogen 3.050 N/A VAL 236.A N MET 218.A O no hydrogen 3.002 N/A GLY 237.A N ARG 279.A O no hydrogen 2.912 N/A PHE 238.A N LYS 216.A O no hydrogen 2.468 N/A LEU 239.A N ILE 277.A O no hydrogen 3.141 N/A ARG 241.A N HIS 275.A O no hydrogen 3.079 N/A ARG 241.A NH1 SER 274.A O no hydrogen 3.462 N/A ARG 241.A NH2 LEU 266.A O no hydrogen 2.340 N/A GLU 243.A N VAL 240.A O no hydrogen 3.146 N/A PHE 244.A N ARG 241.A O no hydrogen 3.048 N/A SER 249.A N ASN 247.A OD1 no hydrogen 3.360 N/A ASN 250.A N ASN 247.A O no hydrogen 2.860 N/A CYS 251.A N ASP 248.A O no hydrogen 3.410 N/A CYS 256.A SG LYS 255.A O no hydrogen 3.469 N/A SER 259.A OG PRO 369.A O no hydrogen 2.442 N/A ASN 263.A N LYS 260.A O no hydrogen 3.056 N/A ASN 263.A ND2 PRO 369.A O no hydrogen 2.744 N/A LEU 266.A N GLU 262.A O no hydrogen 2.894 N/A SER 267.A N ASN 263.A O no hydrogen 2.896 N/A SER 267.A OG ASN 263.A O no hydrogen 3.166 N/A GLY 269.A N LEU 266.A O no hydrogen 3.386 N/A SER 274.A N ARG 271.A O no hydrogen 2.950 N/A SER 274.A OG ARG 271.A O no hydrogen 3.303 N/A SER 274.A OG TYR 276.A O no hydrogen 2.534 N/A TYR 276.A OH ASP 215.A OD2 no hydrogen 2.285 N/A ILE 277.A N LEU 239.A O no hydrogen 2.731 N/A LEU 278.A N MET 268.A O no hydrogen 2.537 N/A ARG 279.A N GLY 237.A O no hydrogen 3.107 N/A ARG 279.A NH2 ILE 300.A O no hydrogen 2.446 N/A GLY 281.A N ALA 235.A O no hydrogen 3.231 N/A LEU 282.A N ILE 298.A O no hydrogen 2.683 N/A LEU 283.A N PHE 233.A O no hydrogen 2.824 N/A LYS 284.A N VAL 296.A O no hydrogen 2.481 N/A TYR 285.A N LEU 231.A O no hydrogen 2.854 N/A LEU 287.A N ASP 229.A O no hydrogen 2.775 N/A SER 288.A N ASN 286.A OD1 no hydrogen 3.064 N/A SER 288.A OG ASP 229.A OD2 no hydrogen 2.615 N/A LYS 294.A NZ GLU 210.A OE2 no hydrogen 2.705 N/A PHE 297.A N GLU 210.A O no hydrogen 3.118 N/A ILE 298.A N LEU 282.A O no hydrogen 2.806 N/A ILE 300.A N SER 280.A O no hydrogen 3.009 N/A SER 301.A N LEU 344.A O no hydrogen 2.818 N/A ASP 302.A N ASP 302.A OD1 no hydrogen 2.369 N/A GLN 303.A NE2 VAL 346.A O no hydrogen 2.879 N/A ARG 304.A NH1 ASP 330.A OD2 no hydrogen 2.931 N/A ARG 304.A NH2 ARG 349.A O no hydrogen 3.200 N/A SER 306.A OG ILE 307.A O no hydrogen 3.403 N/A GLY 308.A N LEU 278.A O no hydrogen 2.698 N/A SER 309.A OG ALA 325.A O no hydrogen 2.360 N/A SER 311.A N TYR 220.A O no hydrogen 2.979 N/A SER 311.A OG TYR 220.A O no hydrogen 3.551 N/A LYS 312.A N TYR 323.A O no hydrogen 2.422 N/A LYS 312.A NZ ASP 379.A OD2 no hydrogen 2.566 N/A LYS 312.A NZ ASN 433.A OD1 no hydrogen 2.518 N/A TYR 314.A N VAL 321.A O no hydrogen 2.605 N/A TYR 314.A OH ALA 380.A O no hydrogen 2.261 N/A SER 316.A OG LEU 382.A O no hydrogen 2.328 N/A LEU 317.A N LEU 50.A O no hydrogen 3.042 N/A GLN 319.A N LEU 317.A O no hydrogen 2.970 N/A GLN 319.A NE2 VAL 338.A O no hydrogen 3.200 N/A VAL 321.A N TYR 314.A O no hydrogen 2.675 N/A PHE 322.A N GLY 336.A O no hydrogen 2.901 N/A TYR 323.A N LYS 312.A O no hydrogen 2.397 N/A GLN 324.A N LYS 334.A O no hydrogen 3.013 N/A SER 326.A OG ASP 330.A O no hydrogen 3.341 N/A SER 326.A OG THR 331.A O no hydrogen 3.366 N/A SER 326.A OG MET 332.A O no hydrogen 2.735 N/A TRP 329.A N SER 328.A OG no hydrogen 2.505 N/A THR 331.A N ASN 366.A O no hydrogen 2.800 N/A THR 331.A OG1 ASN 366.A O no hydrogen 2.572 N/A ILE 333.A N ILE 354.A O no hydrogen 2.824 N/A LYS 334.A NZ ARG 304.A O no hydrogen 3.048 N/A LYS 334.A NZ SER 306.A OG no hydrogen 2.590 N/A LYS 334.A NZ GLN 324.A OE1 no hydrogen 2.748 N/A GLY 336.A N PHE 322.A O no hydrogen 3.031 N/A VAL 338.A N PRO 320.A O no hydrogen 2.832 N/A LEU 339.A N VAL 345.A O no hydrogen 2.997 N/A ASN 347.A N ASP 337.A O no hydrogen 3.122 N/A TRP 348.A NE1 GLN 303.A O no hydrogen 3.259 N/A ARG 349.A N PHE 335.A O no hydrogen 2.853 N/A ARG 349.A NE ASP 411.A OD2 no hydrogen 2.893 N/A ARG 349.A NH2 ASP 411.A OD2 no hydrogen 2.859 N/A THR 352.A N ASP 411.A O no hydrogen 3.249 N/A SER 355.A OG THR 331.A O no hydrogen 3.020 N/A SER 355.A OG ARG 356.A O no hydrogen 3.075 N/A ARG 356.A N SER 355.A OG no hydrogen 2.468 N/A ARG 356.A NE SER 326.A O no hydrogen 2.369 N/A ARG 356.A NH1 CYS 362.A O no hydrogen 2.695 N/A CYS 362.A N GLU 374.A OE2 no hydrogen 2.709 N/A CYS 362.A SG SER 328.A O no hydrogen 3.912 N/A ARG 364.A NH1 ASP 396.A OD1 no hydrogen 2.577 N/A PHE 365.A N SER 355.A OG no hydrogen 3.309 N/A ASN 366.A N THR 331.A OG1 no hydrogen 2.541 N/A CYS 368.A N ASN 366.A OD1 no hydrogen 2.853 N/A CYS 368.A SG SER 259.A OG no hydrogen 2.798 N/A ASN 378.A ND2 GLN 428.A O no hydrogen 3.454 N/A ASN 378.A ND2 THR 430.A OG1 no hydrogen 3.422 N/A ASP 379.A N THR 430.A O no hydrogen 3.382 N/A PHE 381.A N ALA 391.A O no hydrogen 2.704 N/A ILE 383.A N ILE 389.A O no hydrogen 2.872 N/A ASP 384.A N ILE 389.A O no hydrogen 2.894 N/A ARG 385.A NE LEU 317.A O no hydrogen 2.645 N/A ARG 385.A NH1 ASP 337.A OD1 no hydrogen 2.747 N/A ARG 385.A NH2 SER 316.A O no hydrogen 2.347 N/A ARG 385.A NH2 ASP 337.A OD1 no hydrogen 3.506 N/A ASN 387.A ND2 ASP 384.A OD2 no hydrogen 3.297 N/A TRP 388.A N ARG 385.A O no hydrogen 3.305 N/A ILE 389.A N ASP 384.A O no hydrogen 2.720 N/A SER 390.A N PHE 409.A O no hydrogen 3.104 N/A ALA 391.A N PHE 381.A O no hydrogen 2.687 N/A GLY 392.A N THR 407.A O no hydrogen 2.958 N/A VAL 393.A N THR 432.A OG1 no hydrogen 3.208 N/A PHE 394.A N VAL 405.A O no hydrogen 2.782 N/A ASP 396.A N GLU 402.A O no hydrogen 3.198 N/A ASP 396.A N ASN 403.A O no hydrogen 3.037 N/A SER 397.A OG THR 400.A O no hydrogen 2.213 N/A SER 397.A OG THR 400.A OG1 no hydrogen 3.098 N/A SER 397.A OG GLU 402.A O no hydrogen 3.458 N/A THR 400.A OG1 SER 397.A OG no hydrogen 3.098 N/A ASN 403.A N THR 425.A O no hydrogen 3.054 N/A ASN 403.A ND2 ASP 396.A O no hydrogen 3.667 N/A VAL 405.A N PHE 394.A O no hydrogen 3.108 N/A PHE 406.A N ALA 418.A O no hydrogen 2.602 N/A THR 407.A N GLY 392.A O no hydrogen 2.747 N/A THR 407.A OG1 VAL 405.A O no hydrogen 3.282 N/A VAL 408.A N TYR 416.A O no hydrogen 3.153 N/A PHE 409.A N SER 390.A O no hydrogen 2.951 N/A LYS 410.A N GLU 413.A O no hydrogen 2.437 N/A LEU 415.A N VAL 408.A O no hydrogen 2.772 N/A TYR 416.A N VAL 408.A O no hydrogen 3.380 N/A TYR 416.A OH CYS 58.A O no hydrogen 2.856 N/A ARG 417.A NH2 ASP 396.A OD2 no hydrogen 2.320 N/A ALA 418.A N PHE 406.A O no hydrogen 2.780 N/A LEU 420.A N PRO 404.A O no hydrogen 2.961 N/A SER 422.A OG ASP 424.A OD1 no hydrogen 3.141 N/A SER 422.A OG THR 425.A OG1 no hydrogen 2.334 N/A THR 425.A N SER 422.A O no hydrogen 3.348 N/A THR 425.A OG1 SER 422.A O no hydrogen 2.996 N/A THR 425.A OG1 SER 422.A OG no hydrogen 2.334 N/A ALA 427.A N ALA 401.A O no hydrogen 2.748 N/A GLN 428.A N GLU 448.A O no hydrogen 3.187 N/A LYS 429.A NZ PRO 89.A O no hydrogen 2.956 N/A THR 430.A N TYR 377.A O no hydrogen 3.053 N/A THR 430.A OG1 VAL 393.A O no hydrogen 2.704 N/A ILE 431.A N LEU 446.A O no hydrogen 3.156 N/A THR 432.A N ASP 379.A OD1 no hydrogen 2.591 N/A ASN 433.A N ILE 444.A O no hydrogen 3.453 N/A ASN 433.A ND2 LEU 91.A O no hydrogen 2.485 N/A PHE 435.A N TRP 442.A O no hydrogen 2.734 N/A LEU 436.A N SER 48.A O no hydrogen 2.954 N/A LEU 437.A N LYS 440.A O no hydrogen 2.889 N/A LYS 438.A NZ GLU 45.A OE2 no hydrogen 2.839 N/A LYS 440.A N LEU 437.A O no hydrogen 2.904 N/A TRP 442.A N PHE 435.A O no hydrogen 2.881 N/A CYS 443.A N VAL 464.A O no hydrogen 2.739 N/A SER 445.A N PHE 462.A O no hydrogen 3.052 N/A SER 445.A OG CYS 443.A O no hydrogen 2.808 N/A VAL 447.A N LYS 460.A O no hydrogen 3.129 N/A ILE 449.A N VAL 447.A O no hydrogen 2.798 N/A TYR 450.A N ASN 426.A O no hydrogen 2.692 N/A ASN 455.A ND2 ASP 451.A OD2 no hydrogen 2.320 N/A LYS 460.A N VAL 447.A O no hydrogen 2.782 N/A ILE 466.A N ILE 441.A O no hydrogen 2.635 N/A