Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8oo5_P.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ARG 2.A N GLU 298.A O no hydrogen 3.039 N/A ARG 2.A NH1 GLU 298.A OE2 no hydrogen 2.672 N/A ILE 4.A N LEU 296.A O no hydrogen 2.817 N/A SER 5.A N LEU 296.A O no hydrogen 3.206 N/A SER 5.A OG VAL 43.A O no hydrogen 2.796 N/A SER 5.A OG PHE 44.A O no hydrogen 2.859 N/A PHE 7.A N CYS 294.A O no hydrogen 2.914 N/A ARG 8.A NH1 ASP 291.A OD1 no hydrogen 2.477 N/A ARG 8.A NH1 ASP 291.A OD2 no hydrogen 3.472 N/A ARG 8.A NH2 GLU 12.A O no hydrogen 3.477 N/A GLU 9.A N SER 15.A OG no hydrogen 2.939 N/A ALA 10.A N TYR 41.A OH no hydrogen 2.848 N/A SER 15.A OG THR 292.A O no hydrogen 2.715 N/A GLY 16.A N GLU 9.A OE1 no hydrogen 2.758 N/A THR 18.A N GLY 32.A O no hydrogen 2.895 N/A THR 18.A OG1 ILE 59.A O no hydrogen 2.702 N/A CYS 19.A SG ILE 59.A O no hydrogen 3.881 N/A CYS 20.A N ASP 266.A OD2 no hydrogen 2.963 N/A ALA 21.A N MET 30.A O no hydrogen 2.925 N/A SER 23.A N PHE 28.A O no hydrogen 3.181 N/A SER 23.A OG ARG 25.A O no hydrogen 2.924 N/A SER 23.A OG PHE 28.A O no hydrogen 3.151 N/A LEU 29.A N TYR 41.A O no hydrogen 2.716 N/A MET 30.A N ALA 21.A O no hydrogen 2.771 N/A LEU 31.A N LYS 39.A O no hydrogen 2.920 N/A GLY 32.A N CYS 19.A O no hydrogen 2.965 N/A THR 33.A N GLN 37.A O no hydrogen 2.988 N/A THR 33.A OG1 THR 35.A OG1 no hydrogen 3.079 N/A CYS 34.A N GLY 16.A O no hydrogen 2.832 N/A THR 35.A N THR 33.A OG1 no hydrogen 3.256 N/A THR 35.A OG1 THR 33.A OG1 no hydrogen 3.079 N/A THR 35.A OG1 GLN 37.A OE1 no hydrogen 3.445 N/A GLY 36.A N THR 33.A O no hydrogen 3.004 N/A GLN 37.A N THR 33.A OG1 no hydrogen 3.030 N/A LEU 38.A N TYR 52.A O no hydrogen 2.722 N/A LYS 39.A N LEU 31.A O no hydrogen 2.861 N/A LYS 39.A NZ GLU 9.A OE2 no hydrogen 2.909 N/A LYS 39.A NZ GLU 48.A OE1 no hydrogen 2.997 N/A LEU 40.A N ALA 50.A O no hydrogen 2.834 N/A TYR 41.A N LEU 29.A O no hydrogen 2.887 N/A ASN 42.A N GLN 47.A O no hydrogen 3.014 N/A VAL 43.A N ARG 27.A O no hydrogen 3.018 N/A PHE 44.A N ASN 42.A OD1 no hydrogen 2.927 N/A SER 45.A N ASN 42.A OD1 no hydrogen 3.058 N/A GLY 46.A N ASN 42.A O no hydrogen 2.789 N/A GLN 47.A N SER 45.A OG no hydrogen 3.167 N/A GLU 49.A N LEU 40.A O no hydrogen 2.611 N/A ALA 50.A N LEU 40.A O no hydrogen 3.420 N/A TYR 52.A N LEU 38.A O no hydrogen 2.881 N/A ASN 53.A ND2 ASN 56.A OD1 no hydrogen 3.041 N/A CYS 54.A N GLY 36.A O no hydrogen 3.002 N/A HIS 55.A N GLY 36.A O no hydrogen 3.081 N/A HIS 55.A NE2 THR 73.A OG1 no hydrogen 2.664 N/A SER 57.A OG SER 78.A OG no hydrogen 2.753 N/A ILE 59.A N THR 33.A O no hydrogen 2.953 N/A THR 60.A N SER 74.A O no hydrogen 2.777 N/A THR 60.A OG1 SER 74.A O no hydrogen 3.247 N/A HIS 61.A N SER 74.A O no hydrogen 3.458 N/A GLU 63.A N LEU 72.A O no hydrogen 3.030 N/A SER 65.A N LEU 70.A O no hydrogen 2.937 N/A SER 65.A OG ASP 67.A OD1 no hydrogen 2.546 N/A SER 65.A OG LEU 70.A O no hydrogen 3.370 N/A ARG 66.A N GLN 110.A OE1 no hydrogen 2.926 N/A ARG 66.A NH1 LYS 107.A O no hydrogen 2.857 N/A ARG 66.A NH2 LYS 107.A O no hydrogen 2.966 N/A ARG 66.A NH2 HIS 108.A O no hydrogen 2.824 N/A GLY 68.A N SER 65.A O no hydrogen 3.146 N/A SER 69.A N SER 65.A OG no hydrogen 3.255 N/A SER 69.A N ASP 67.A OD1 no hydrogen 2.925 N/A SER 69.A OG ASP 67.A OD1 no hydrogen 2.673 N/A SER 69.A OG ASP 67.A OD2 no hydrogen 3.172 N/A LEU 70.A N SER 65.A OG no hydrogen 3.063 N/A LEU 71.A N TRP 85.A O no hydrogen 2.871 N/A LEU 72.A N GLU 63.A O no hydrogen 2.826 N/A THR 73.A N ALA 83.A O no hydrogen 3.002 N/A THR 73.A OG1 HIS 55.A NE2 no hydrogen 2.664 N/A SER 74.A N HIS 61.A O no hydrogen 3.075 N/A SER 74.A OG SER 82.A OG no hydrogen 2.776 N/A SER 74.A OG HIS 101.A O no hydrogen 3.545 N/A ALA 75.A N LEU 81.A O no hydrogen 2.863 N/A THR 76.A OG1 ALA 58.A O no hydrogen 3.209 N/A TRP 77.A N SER 57.A OG no hydrogen 2.907 N/A SER 78.A OG SER 57.A OG no hydrogen 2.753 N/A LEU 81.A N THR 98.A O no hydrogen 2.952 N/A SER 82.A N PHE 97.A O no hydrogen 3.179 N/A SER 82.A OG SER 74.A OG no hydrogen 2.776 N/A SER 82.A OG ASP 100.A O no hydrogen 2.574 N/A ALA 83.A N THR 73.A O no hydrogen 2.934 N/A LEU 84.A N HIS 95.A O no hydrogen 2.931 N/A TRP 85.A N LEU 71.A O no hydrogen 2.815 N/A TRP 85.A NE1 THR 73.A OG1 no hydrogen 2.932 N/A GLY 86.A N ASP 92.A O no hydrogen 2.886 N/A MET 87.A N SER 69.A O no hydrogen 2.841 N/A VAL 90.A N LYS 88.A O no hydrogen 3.014 N/A ASP 92.A N GLY 86.A O no hydrogen 3.158 N/A LYS 94.A N LEU 84.A O no hydrogen 2.795 N/A LYS 94.A NZ ASP 92.A OD1 no hydrogen 3.270 N/A LYS 94.A NZ ASP 92.A OD2 no hydrogen 3.291 N/A HIS 95.A N LEU 84.A O no hydrogen 3.344 N/A HIS 95.A NE2 GLN 127.A O no hydrogen 3.283 N/A PHE 97.A N SER 82.A O no hydrogen 2.871 N/A HIS 101.A N THR 116.A O no hydrogen 2.869 N/A TYR 102.A OH GLU 104.A OE2 no hydrogen 2.533 N/A GLU 104.A N ILE 114.A O no hydrogen 2.983 N/A PHE 105.A N GLU 63.A OE1 no hydrogen 3.021 N/A SER 106.A N ARG 112.A O no hydrogen 2.969 N/A SER 106.A OG SER 109.A O no hydrogen 2.685 N/A SER 106.A OG ASP 111.A OD1 no hydrogen 3.438 N/A SER 106.A OG ARG 112.A O no hydrogen 3.308 N/A LYS 107.A N ASP 155.A OD1 no hydrogen 2.635 N/A LYS 107.A NZ GLU 104.A OE1 no hydrogen 3.424 N/A LYS 107.A NZ PHE 151.A O no hydrogen 2.904 N/A HIS 108.A N ASP 155.A OD1 no hydrogen 3.042 N/A HIS 108.A N ASP 155.A OD2 no hydrogen 3.185 N/A SER 109.A N ASP 155.A OD2 no hydrogen 3.039 N/A GLN 110.A NE2 SER 106.A O no hydrogen 3.390 N/A ASP 111.A N SER 106.A OG no hydrogen 3.254 N/A ARG 112.A N SER 106.A OG no hydrogen 3.166 N/A VAL 113.A N TYR 124.A O no hydrogen 2.937 N/A ILE 114.A N GLU 104.A O no hydrogen 2.887 N/A GLY 115.A N HIS 122.A O no hydrogen 2.772 N/A THR 116.A N TYR 102.A O no hydrogen 2.828 N/A LYS 117.A N ILE 120.A O no hydrogen 2.826 N/A LYS 117.A NZ GLU 99.A OE1 no hydrogen 3.245 N/A ILE 120.A N LYS 117.A O no hydrogen 3.054 N/A ALA 121.A N LEU 135.A O no hydrogen 2.950 N/A HIS 122.A N GLY 115.A O no hydrogen 2.813 N/A HIS 122.A ND1 ASP 100.A OD1 no hydrogen 2.940 N/A ILE 123.A N LEU 133.A O no hydrogen 2.974 N/A TYR 124.A N VAL 113.A O no hydrogen 2.721 N/A TYR 124.A OH ASP 100.A OD2 no hydrogen 2.459 N/A ASP 125.A N ASN 130.A O no hydrogen 2.911 N/A ILE 126.A N ASP 111.A O no hydrogen 2.907 N/A THR 128.A N ASP 125.A OD2 no hydrogen 2.884 N/A THR 128.A OG1 ASP 125.A OD2 no hydrogen 2.801 N/A GLY 129.A N ASP 125.A O no hydrogen 2.743 N/A ASN 130.A N THR 128.A OG1 no hydrogen 3.254 N/A LEU 132.A N ILE 123.A O no hydrogen 2.854 N/A LEU 133.A N ILE 123.A O no hydrogen 3.429 N/A LEU 135.A N ALA 121.A O no hydrogen 2.814 N/A ASP 139.A N ASN 137.A OD1 no hydrogen 2.987 N/A LEU 140.A N ASN 137.A O no hydrogen 2.893 N/A ASN 142.A N ASP 161.A OD2 no hydrogen 2.957 N/A ASN 142.A ND2 ASP 161.A O no hydrogen 3.170 N/A ASN 142.A ND2 PHE 176.A O no hydrogen 3.308 N/A ASN 143.A N ASP 161.A OD2 no hydrogen 2.947 N/A ASN 143.A ND2 ASP 119.A OD2 no hydrogen 2.879 N/A TYR 144.A N ASP 161.A OD1 no hydrogen 2.867 N/A LYS 145.A N MET 181.A O no hydrogen 3.019 N/A ARG 146.A N ASN 182.A O no hydrogen 2.903 N/A ASN 147.A ND2 GLY 118.A O no hydrogen 2.985 N/A ASN 147.A ND2 ASN 160.A OD1 no hydrogen 2.880 N/A CYS 148.A N SER 184.A OG no hydrogen 3.209 N/A CYS 148.A SG ARG 146.A O no hydrogen 3.718 N/A ALA 149.A N THR 116.A OG1 no hydrogen 2.811 N/A THR 150.A N LEU 159.A O no hydrogen 3.061 N/A THR 150.A OG1 GLU 104.A OE1 no hydrogen 2.775 N/A THR 150.A OG1 PHE 151.A O no hydrogen 3.234 N/A ASN 152.A N LEU 157.A O no hydrogen 2.882 N/A ASN 152.A ND2 ASP 156.A OD1 no hydrogen 3.107 N/A THR 154.A OG1 ASP 156.A OD1 no hydrogen 2.740 N/A ASP 155.A N ASN 152.A O no hydrogen 2.998 N/A ASP 156.A N ASN 152.A OD1 no hydrogen 2.980 N/A LEU 157.A N ASN 152.A OD1 no hydrogen 3.008 N/A VAL 158.A N TRP 165.A O no hydrogen 2.951 N/A LEU 159.A N THR 150.A O no hydrogen 2.910 N/A ASN 160.A N VAL 163.A O no hydrogen 2.868 N/A ASN 160.A ND2 ASP 119.A O no hydrogen 2.830 N/A ASP 161.A N ASN 147.A OD1 no hydrogen 2.842 N/A VAL 163.A N ASN 160.A O no hydrogen 2.914 N/A LEU 164.A N HIS 174.A O no hydrogen 2.824 N/A TRP 165.A N VAL 158.A O no hydrogen 2.828 N/A ASP 166.A N LEU 171.A O no hydrogen 2.847 N/A VAL 167.A N ASP 156.A O no hydrogen 3.041 N/A SER 169.A N ASP 166.A OD1 no hydrogen 2.958 N/A SER 169.A OG ASP 166.A OD1 no hydrogen 3.050 N/A ALA 170.A N VAL 167.A O no hydrogen 3.347 N/A LEU 171.A N ASP 166.A O no hydrogen 3.268 N/A ILE 173.A N LEU 164.A O no hydrogen 2.798 N/A LYS 175.A NZ ASN 142.A OD1 no hydrogen 2.804 N/A LYS 175.A NZ PHE 176.A O no hydrogen 3.429 N/A PHE 176.A N GLY 162.A O no hydrogen 2.825 N/A LYS 178.A NZ ASN 142.A O no hydrogen 2.793 N/A ASN 182.A ND2 GLN 217.A OE1 no hydrogen 2.698 N/A SER 184.A OG ASN 147.A OD1 no hydrogen 3.415 N/A VAL 186.A N ILE 195.A O no hydrogen 2.938 N/A HIS 188.A N GLU 193.A O no hydrogen 2.931 N/A HIS 188.A NE2 ALA 249.A O no hydrogen 2.851 N/A ASN 190.A N HIS 188.A ND1 no hydrogen 2.883 N/A GLY 191.A N HIS 188.A O no hydrogen 3.071 N/A LEU 192.A N ASN 190.A OD1 no hydrogen 2.767 N/A VAL 194.A N TRP 201.A O no hydrogen 2.835 N/A ILE 195.A N VAL 186.A O no hydrogen 2.928 N/A ILE 196.A N GLU 199.A O no hydrogen 2.870 N/A ASN 197.A ND2 ASP 216.A OD1 no hydrogen 2.837 N/A THR 198.A OG1 GLU 199.A OE1 no hydrogen 2.929 N/A THR 198.A OG1 GLU 199.A OE2 no hydrogen 2.323 N/A GLU 199.A N ILE 196.A O no hydrogen 3.039 N/A ILE 200.A N HIS 210.A O no hydrogen 3.019 N/A TRP 201.A N VAL 194.A O no hydrogen 2.885 N/A ASP 202.A N HIS 207.A O no hydrogen 3.001 N/A LEU 203.A N LEU 192.A O no hydrogen 2.807 N/A ARG 204.A N ASP 202.A OD1 no hydrogen 2.656 N/A ARG 204.A NE ASP 202.A OD1 no hydrogen 3.211 N/A ARG 204.A NH2 ASP 202.A OD2 no hydrogen 2.839 N/A THR 205.A N ASP 202.A OD1 no hydrogen 3.194 N/A PHE 206.A N ASP 202.A O no hydrogen 2.757 N/A HIS 207.A N THR 205.A OG1 no hydrogen 3.170 N/A LEU 209.A N ILE 200.A O no hydrogen 2.789 N/A HIS 210.A N ILE 200.A O no hydrogen 3.480 N/A VAL 212.A N THR 198.A O no hydrogen 2.751 N/A LEU 215.A N VAL 212.A O no hydrogen 3.098 N/A ASP 216.A N PRO 213.A O no hydrogen 3.033 N/A GLN 217.A N ASN 197.A OD1 no hydrogen 2.708 N/A GLN 217.A NE2 ASP 216.A OD1 no hydrogen 3.150 N/A CYS 218.A N LEU 215.A O no hydrogen 3.052 N/A CYS 218.A SG ALA 214.A O no hydrogen 3.759 N/A CYS 218.A SG ASP 216.A O no hydrogen 3.635 N/A ARG 219.A N ALA 232.A O no hydrogen 3.043 N/A VAL 221.A N TYR 230.A O no hydrogen 2.903 N/A ASN 223.A N VAL 228.A O no hydrogen 3.026 N/A ASN 223.A ND2 THR 227.A OG1 no hydrogen 2.845 N/A HIS 224.A N ASP 273.A OD1 no hydrogen 2.877 N/A HIS 224.A ND1 ASP 273.A OD1 no hydrogen 3.250 N/A THR 225.A N ASP 273.A OD2 no hydrogen 2.927 N/A THR 225.A OG1 THR 227.A OG1 no hydrogen 3.013 N/A THR 225.A OG1 ASP 273.A OD2 no hydrogen 2.997 N/A GLY 226.A N ASN 223.A O no hydrogen 3.236 N/A THR 227.A N ASN 223.A OD1 no hydrogen 2.971 N/A THR 227.A OG1 THR 225.A OG1 no hydrogen 3.013 N/A VAL 228.A N ASN 223.A OD1 no hydrogen 3.049 N/A MET 229.A N PHE 247.A O no hydrogen 2.904 N/A TYR 230.A N VAL 221.A O no hydrogen 2.794 N/A GLY 231.A N ARG 245.A O.A no hydrogen 2.812 N/A GLY 231.A N ARG 245.A O.B no hydrogen 2.839 N/A LEU 234.A N GLN 217.A O no hydrogen 2.836 N/A GLN 235.A N PRO 239.A O no hydrogen 2.921 N/A SER 238.A OG ILE 264.A O no hydrogen 2.579 N/A PHE 240.A N SER 238.A OG no hydrogen 3.109 N/A GLY 241.A N MET 233.A O no hydrogen 2.922 N/A SER 242.A OG ASP 259.A OD1 no hydrogen 2.719 N/A PHE 244.A N ILE 258.A O no hydrogen 2.877 N/A ARG 245.A N.A GLY 231.A O no hydrogen 2.812 N/A ARG 245.A N.B GLY 231.A O no hydrogen 2.847 N/A THR 246.A N ALA 256.A O no hydrogen 2.792 N/A THR 246.A OG1 ALA 256.A O no hydrogen 3.560 N/A PHE 247.A N MET 229.A O no hydrogen 2.919 N/A ASN 248.A N LYS 253.A O no hydrogen 3.068 N/A ALA 249.A N THR 227.A O no hydrogen 3.031 N/A THR 250.A N ASN 248.A OD1 no hydrogen 2.764 N/A ASP 251.A N ASN 248.A OD1 no hydrogen 3.064 N/A TYR 252.A N ASN 248.A O no hydrogen 2.747 N/A TYR 252.A OH GLU 193.A OE2 no hydrogen 2.639 N/A LYS 253.A N ASP 251.A OD1 no hydrogen 3.413 N/A ILE 255.A N THR 246.A O no hydrogen 2.799 N/A ALA 256.A N THR 246.A O no hydrogen 3.450 N/A ILE 258.A N PHE 244.A O no hydrogen 2.938 N/A VAL 260.A N SER 242.A O no hydrogen 2.891 N/A LYS 261.A N ASP 259.A OD1 no hydrogen 2.939 N/A ARG 262.A NE GLU 280.A OE1 no hydrogen 2.843 N/A ARG 262.A NH2 GLU 280.A OE1 no hydrogen 2.709 N/A ILE 264.A N GLY 241.A O no hydrogen 2.909 N/A PHE 265.A N ILE 279.A O no hydrogen 2.835 N/A LEU 267.A N ASP 266.A OD1 no hydrogen 2.943 N/A CYS 268.A N ALA 277.A O no hydrogen 2.943 N/A THR 269.A OG1 HIS 224.A ND1 no hydrogen 3.186 N/A THR 269.A OG1 ASP 270.A O no hydrogen 3.254 N/A THR 269.A OG1 ASP 273.A OD1 no hydrogen 3.129 N/A ASP 270.A N TYR 275.A O no hydrogen 3.411 N/A ASP 273.A N ASP 270.A O no hydrogen 2.868 N/A CYS 274.A N ASP 270.A OD1 no hydrogen 2.862 N/A CYS 274.A SG LYS 272.A O no hydrogen 3.995 N/A TYR 275.A N ASP 270.A OD1 no hydrogen 2.868 N/A LEU 276.A N TYR 297.A O no hydrogen 2.833 N/A ALA 277.A N CYS 268.A O no hydrogen 2.866 N/A VAL 278.A N ARG 295.A O no hydrogen 2.706 N/A ILE 279.A N ASP 266.A O no hydrogen 2.914 N/A GLU 280.A N VAL 293.A O no hydrogen 2.957 N/A ASN 281.A N ASN 263.A O no hydrogen 2.854 N/A GLN 282.A N ASP 291.A O no hydrogen 2.990 N/A GLY 283.A N ASN 281.A OD1 no hydrogen 3.141 N/A ALA 287.A N SER 284.A O no hydrogen 3.265 N/A ASP 291.A N ASN 281.A OD1 no hydrogen 3.225 N/A THR 292.A N SER 15.A O no hydrogen 2.862 N/A THR 292.A OG1 SER 15.A O no hydrogen 3.331 N/A THR 292.A OG1 PHE 17.A O no hydrogen 2.761 N/A VAL 293.A N GLU 280.A O no hydrogen 2.752 N/A CYS 294.A N PHE 7.A O no hydrogen 2.723 N/A ARG 295.A N VAL 278.A O no hydrogen 2.725 N/A ARG 295.A NE TYR 297.A OH no hydrogen 2.899 N/A LEU 296.A N SER 5.A O no hydrogen 2.826 N/A TYR 297.A N LEU 276.A O no hydrogen 2.825 N/A TYR 297.A OH GLU 280.A OE2 no hydrogen 2.549 N/A GLU 298.A N ARG 2.A O no hydrogen 2.868 N/A VAL 299.A N CYS 274.A O no hydrogen 3.281 N/A