Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8orq_C.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): SER 2.A OG SER 4.A OG no hydrogen 2.904 N/A SER 2.A OG THR 5.A OG1 no hydrogen 3.037 N/A SER 4.A OG SER 2.A OG no hydrogen 2.904 N/A THR 5.A N SER 2.A O no hydrogen 2.634 N/A THR 5.A OG1 SER 2.A O no hydrogen 3.224 N/A THR 5.A OG1 SER 2.A OG no hydrogen 3.037 N/A ILE 6.A N SER 2.A O no hydrogen 3.395 N/A LYS 7.A N LEU 3.A O no hydrogen 2.963 N/A SER 8.A N SER 4.A O no hydrogen 2.874 N/A SER 8.A OG THR 5.A O no hydrogen 2.819 N/A LEU 9.A N THR 5.A O no hydrogen 2.891 N/A ILE 10.A N ILE 6.A O no hydrogen 2.888 N/A GLU 11.A N LYS 7.A O no hydrogen 2.957 N/A LYS 12.A N SER 8.A O no hydrogen 2.858 N/A LYS 12.A NZ LYS 12.A O no hydrogen 2.655 N/A LYS 13.A N LEU 9.A O no hydrogen 2.929 N/A LYS 13.A NZ ASP 48.A OD1 no hydrogen 3.304 N/A GLY 14.A N ILE 10.A O no hydrogen 2.901 N/A LEU 17.A N GLY 14.A O no hydrogen 3.275 N/A LYS 22.A N PRO 18.A O no hydrogen 3.118 N/A LYS 22.A NZ GLY 14.A O no hydrogen 3.344 N/A LYS 22.A NZ ALA 15.A O no hydrogen 3.434 N/A LYS 22.A NZ LEU 17.A O no hydrogen 3.271 N/A SER 23.A N GLU 19.A O no hydrogen 2.939 N/A SER 23.A OG GLU 19.A O no hydrogen 3.119 N/A SER 23.A OG ASN 20.A O no hydrogen 2.684 N/A GLU 24.A N ASN 20.A O no hydrogen 2.918 N/A LEU 25.A N VAL 21.A O no hydrogen 2.890 N/A TYR 26.A N LYS 22.A O no hydrogen 2.882 N/A GLU 27.A N SER 23.A O no hydrogen 2.964 N/A LYS 28.A N GLU 24.A O no hydrogen 2.976 N/A LYS 28.A NZ GLU 24.A OE2 no hydrogen 2.467 N/A LEU 29.A N LEU 25.A O no hydrogen 2.850 N/A LYS 30.A N TYR 26.A O no hydrogen 2.916 N/A LYS 30.A NZ TYR 26.A OH no hydrogen 3.038 N/A LYS 31.A N GLU 27.A O no hydrogen 3.001 N/A TYR 32.A N LYS 28.A O no hydrogen 2.908 N/A ASN 33.A N LEU 29.A O no hydrogen 2.863 N/A ASN 33.A ND2 VAL 1.A O no hydrogen 3.299 N/A GLU 34.A N LYS 30.A O no hydrogen 2.952 N/A LYS 35.A N LYS 31.A O no hydrogen 2.974 N/A TYR 36.A N TYR 32.A O no hydrogen 2.863 N/A LYS 37.A N ASN 33.A O no hydrogen 2.836 N/A LYS 37.A NZ GLU 34.A O no hydrogen 2.460 N/A THR 39.A N GLU 42.A OE2 no hydrogen 3.170 N/A THR 39.A OG1 GLU 42.A OE1 no hydrogen 2.113 N/A THR 39.A OG1 GLU 42.A OE2 no hydrogen 3.159 N/A GLU 42.A N GLU 42.A OE1 no hydrogen 2.504 N/A ILE 43.A N THR 39.A O no hydrogen 3.287 N/A GLU 44.A N LYS 40.A O no hydrogen 2.905 N/A ALA 45.A N ALA 41.A O no hydrogen 2.946 N/A ILE 46.A N GLU 42.A O no hydrogen 2.862 N/A ILE 47.A N ILE 43.A O no hydrogen 2.928 N/A ASP 48.A N GLU 44.A O no hydrogen 2.924 N/A ASP 49.A N ALA 45.A O no hydrogen 2.911 N/A VAL 50.A N ILE 46.A O no hydrogen 2.911 N/A VAL 51.A N ILE 47.A O no hydrogen 2.910 N/A LYS 52.A N ASP 48.A O no hydrogen 2.920 N/A GLU 53.A N ASP 49.A O no hydrogen 2.912 N/A TYR 54.A N VAL 50.A O no hydrogen 2.910 N/A GLU 55.A N VAL 51.A O no hydrogen 2.913 N/A ARG 56.A N LYS 52.A O no hydrogen 2.928 N/A ALA 57.A N GLU 53.A O no hydrogen 2.945 N/A ALA 57.A N TYR 54.A O no hydrogen 3.148 N/A LEU 58.A N GLU 55.A O no hydrogen 3.476 N/A VAL 68.A N PRO 64.A O no hydrogen 3.398 N/A ALA 69.A N VAL 65.A O no hydrogen 2.894 N/A ALA 70.A N GLY 66.A O no hydrogen 2.923 N/A GLN 71.A N THR 67.A O no hydrogen 2.913 N/A SER 72.A N VAL 68.A O no hydrogen 2.869 N/A SER 72.A OG ALA 69.A O no hydrogen 3.335 N/A ILE 73.A N ALA 69.A O no hydrogen 2.948 N/A GLY 74.A N ALA 70.A O no hydrogen 2.908 N/A GLU 75.A N GLN 71.A O no hydrogen 2.910 N/A SER 77.A N GLY 74.A O no hydrogen 3.180 N/A SER 77.A OG GLY 74.A O no hydrogen 2.961 N/A THR 78.A N GLU 75.A O no hydrogen 3.111 N/A THR 78.A OG1 GLU 75.A O no hydrogen 3.021 N/A GLN 79.A N PRO 76.A O no hydrogen 2.989 N/A MET 80.A N PRO 76.A O no hydrogen 2.951 N/A MET 80.A N SER 77.A O no hydrogen 3.121 N/A THR 84.A OG1 LEU 82.A O no hydrogen 2.523 N/A THR 96.A N THR 114.A OG1 no hydrogen 3.019 N/A ARG 101.A NH2 GLU 289.A OE1 no hydrogen 3.130 N/A ILE 102.A N GLY 98.A O no hydrogen 2.947 N/A ILE 103.A N LEU 99.A O no hydrogen 2.904 N/A GLU 104.A N PRO 100.A O no hydrogen 2.890 N/A ILE 105.A N ARG 101.A O no hydrogen 2.965 N/A VAL 106.A N ILE 102.A O no hydrogen 2.886 N/A ASP 107.A N ILE 103.A O no hydrogen 2.884 N/A ALA 108.A N ILE 105.A O no hydrogen 3.185 N/A ARG 109.A N GLU 104.A O no hydrogen 3.350 N/A ARG 109.A NH2 GLU 104.A OE2 no hydrogen 3.105 N/A SER 113.A OG GLU 104.A OE2 no hydrogen 2.256 N/A THR 114.A OG1 THR 114.A O no hydrogen 2.621 N/A MET 117.A N THR 246.A O no hydrogen 2.732 N/A THR 118.A N ARG 266.A O no hydrogen 3.014 N/A VAL 119.A N ILE 244.A O no hydrogen 2.952 N/A ASP 122.A N GLY 259.A O no hydrogen 3.285 N/A ARG 126.A NE LEU 121.A O no hydrogen 2.661 N/A ALA 130.A N ASP 128.A OD1 no hydrogen 2.914 N/A LYS 131.A N ASP 128.A OD2 no hydrogen 2.661 N/A ALA 132.A N ASP 128.A O no hydrogen 3.163 N/A GLU 133.A N ARG 129.A O no hydrogen 2.872 N/A GLU 134.A N ALA 130.A O no hydrogen 2.899 N/A VAL 135.A N LYS 131.A O no hydrogen 2.938 N/A ALA 136.A N ALA 132.A O no hydrogen 2.865 N/A ARG 137.A N GLU 133.A O no hydrogen 2.852 N/A ARG 138.A N GLU 134.A O no hydrogen 2.952 N/A ARG 138.A NE GLU 134.A O no hydrogen 3.212 N/A ILE 139.A N VAL 135.A O no hydrogen 2.926 N/A ILE 139.A N ALA 136.A O no hydrogen 2.660 N/A THR 142.A N LYS 225.A O no hydrogen 2.769 N/A THR 142.A OG1 GLU 140.A OE1 no hydrogen 3.288 N/A THR 143.A OG1 GLY 141.A O no hydrogen 3.361 N/A LEU 147.A N THR 143.A O no hydrogen 3.149 N/A ALA 148.A N LEU 144.A O no hydrogen 2.830 N/A SER 150.A N GLU 163.A O no hydrogen 3.078 N/A SER 150.A OG THR 151.A O no hydrogen 3.567 N/A SER 150.A OG GLU 163.A OE2 no hydrogen 2.680 N/A THR 152.A N ILE 161.A O no hydrogen 3.372 N/A THR 152.A OG1 GLU 163.A OE2 no hydrogen 3.569 N/A PHE 158.A N LEU 155.A O no hydrogen 3.502 N/A VAL 162.A N LEU 199.A O no hydrogen 3.418 N/A GLU 163.A N SER 150.A O no hydrogen 2.747 N/A GLU 163.A N GLU 163.A OE1 no hydrogen 2.657 N/A ILE 164.A N TYR 197.A O no hydrogen 3.215 N/A ASP 165.A N LEU 147.A O no hydrogen 3.219 N/A GLU 167.A N GLU 167.A OE1 no hydrogen 2.782 N/A ARG 168.A N ASP 165.A OD2 no hydrogen 3.315 N/A LEU 169.A N ASP 165.A O no hydrogen 3.256 N/A GLU 170.A N PRO 166.A O no hydrogen 2.891 N/A ARG 171.A N GLU 167.A O no hydrogen 2.887 N/A ARG 171.A NE ARG 171.A O no hydrogen 3.222 N/A SER 172.A N ARG 168.A O no hydrogen 2.898 N/A SER 172.A OG ARG 168.A O no hydrogen 3.380 N/A SER 172.A OG LEU 169.A O no hydrogen 2.964 N/A GLY 173.A N GLU 170.A O no hydrogen 3.153 N/A LEU 174.A N SER 172.A OG no hydrogen 3.378 N/A THR 175.A OG1 GLU 177.A OE2 no hydrogen 2.173 N/A VAL 179.A N THR 175.A O no hydrogen 2.863 N/A VAL 180.A N MET 176.A O no hydrogen 2.911 N/A LYS 181.A N GLU 177.A O no hydrogen 2.864 N/A LYS 181.A NZ GLU 177.A OE1 no hydrogen 2.636 N/A LYS 182.A N LYS 178.A O no hydrogen 2.930 N/A LEU 183.A N VAL 179.A O no hydrogen 2.885 N/A GLU 184.A N VAL 180.A O no hydrogen 2.907 N/A SER 185.A N LYS 181.A O no hydrogen 2.893 N/A SER 185.A OG LYS 182.A O no hydrogen 2.937 N/A SER 186.A N LYS 182.A O no hydrogen 2.917 N/A SER 186.A N LEU 183.A O no hydrogen 3.076 N/A SER 186.A OG LYS 182.A O no hydrogen 2.987 N/A SER 186.A OG LEU 183.A O no hydrogen 2.570 N/A PHE 187.A N LEU 183.A O no hydrogen 2.403 N/A LYS 188.A NZ SER 186.A O no hydrogen 2.963 N/A ASP 195.A N THR 198.A O no hydrogen 3.296 N/A THR 198.A N ASP 195.A O no hydrogen 3.069 N/A LEU 199.A N VAL 162.A O no hydrogen 3.294 N/A ARG 202.A NH1 GLU 191.A O no hydrogen 3.281 N/A LYS 205.A NZ ALA 206.A O no hydrogen 2.942 N/A SER 210.A OG ASP 211.A OD1 no hydrogen 3.043 N/A LEU 212.A N LYS 208.A O no hydrogen 3.487 N/A ARG 213.A N ILE 209.A O no hydrogen 2.902 N/A ARG 214.A N SER 210.A O no hydrogen 2.893 N/A PHE 215.A N ASP 211.A O no hydrogen 2.924 N/A ALA 216.A N LEU 212.A O no hydrogen 2.834 N/A GLU 217.A N ARG 213.A O no hydrogen 2.939 N/A LYS 218.A N ARG 214.A O no hydrogen 2.857 N/A ILE 219.A N PHE 215.A O no hydrogen 3.012 N/A LYS 220.A N ALA 216.A O no hydrogen 2.868 N/A LYS 221.A N GLU 217.A O no hydrogen 3.312 N/A HIS 222.A N ILE 219.A O no hydrogen 3.072 N/A LEU 224.A N THR 142.A O no hydrogen 3.382 N/A LYS 225.A NZ ARG 138.A O no hydrogen 3.205 N/A LYS 232.A NZ GLU 92.A O no hydrogen 3.002 N/A ILE 234.A N TYR 245.A O no hydrogen 3.084 N/A ARG 236.A N VAL 243.A O no hydrogen 2.969 N/A ARG 236.A NH1 ALA 91.A O no hydrogen 2.424 N/A ARG 236.A NH1 GLU 92.A OE2 no hydrogen 3.396 N/A LYS 237.A NZ GLY 239.A O no hydrogen 3.284 N/A TYR 242.A N ARG 126.A O no hydrogen 3.134 N/A VAL 243.A N ARG 236.A O no hydrogen 3.103 N/A ILE 244.A N VAL 119.A O no hydrogen 2.917 N/A TYR 245.A N ILE 234.A O no hydrogen 3.255 N/A THR 246.A N MET 117.A O no hydrogen 2.982 N/A GLU 247.A N LYS 232.A O no hydrogen 3.269 N/A SER 249.A N GLY 229.A O no hydrogen 3.282 N/A SER 249.A OG SER 249.A O no hydrogen 2.541 N/A PHE 251.A N GLU 272.A OE2 no hydrogen 2.542 N/A GLN 253.A NE2 ASN 250.A OD1 no hydrogen 2.621 N/A VAL 254.A N ASN 250.A O no hydrogen 3.034 N/A LYS 256.A N GLN 253.A O no hydrogen 3.109 N/A LYS 256.A NZ LYS 252.A O no hydrogen 3.143 N/A VAL 257.A N VAL 254.A O no hydrogen 3.014 N/A VAL 260.A N VAL 257.A O no hydrogen 3.292 N/A ASP 261.A N TYR 120.A O no hydrogen 3.091 N/A THR 263.A OG1 ASP 261.A OD1 no hydrogen 3.552 N/A THR 265.A OG1 ASP 261.A O no hydrogen 2.722 N/A ARG 266.A N THR 118.A O no hydrogen 3.035 N/A ARG 266.A NH2 ASP 288.A OD2 no hydrogen 3.219 N/A ASN 268.A N MET 116.A O no hydrogen 2.861 N/A ASN 269.A ND2 LYS 110.A O no hydrogen 3.179 N/A GLU 272.A N ASN 269.A OD1 no hydrogen 3.015 N/A ILE 273.A N ASN 269.A O no hydrogen 3.377 N/A ALA 274.A N ILE 270.A O no hydrogen 2.898 N/A GLU 275.A N HIS 271.A O no hydrogen 2.921 N/A VAL 276.A N GLU 272.A O no hydrogen 2.923 N/A LEU 277.A N ILE 273.A O no hydrogen 2.886 N/A GLY 278.A N ILE 273.A O no hydrogen 3.389 N/A ARG 283.A N ILE 279.A O no hydrogen 2.940 N/A ARG 283.A NE ASP 311.A OD1 no hydrogen 2.892 N/A ARG 283.A NE ASP 311.A OD2 no hydrogen 3.139 N/A ARG 283.A NH2 ASP 311.A OD2 no hydrogen 3.040 N/A ASN 284.A N GLU 280.A O no hydrogen 2.972 N/A ALA 285.A N ALA 281.A O no hydrogen 2.876 N/A ILE 286.A N ALA 282.A O no hydrogen 2.919 N/A ILE 287.A N ARG 283.A O no hydrogen 2.993 N/A ASP 288.A N ASN 284.A O no hydrogen 2.940 N/A GLU 289.A N ALA 285.A O no hydrogen 2.878 N/A ILE 290.A N ILE 286.A O no hydrogen 2.998 N/A VAL 291.A N ILE 287.A O no hydrogen 2.943 N/A SER 292.A N ASP 288.A O no hydrogen 2.918 N/A SER 292.A OG ASP 288.A O no hydrogen 3.183 N/A SER 292.A OG GLU 289.A O no hydrogen 2.768 N/A THR 293.A N GLU 289.A O no hydrogen 2.962 N/A THR 293.A OG1 GLU 289.A O no hydrogen 2.722 N/A MET 294.A N ILE 290.A O no hydrogen 2.930 N/A GLN 295.A N VAL 291.A O no hydrogen 2.890 N/A GLU 296.A N SER 292.A O no hydrogen 2.966 N/A GLY 298.A N GLN 295.A O no hydrogen 2.974 N/A ARG 304.A N ASP 302.A OD1 no hydrogen 2.968 N/A ARG 304.A NE ASP 302.A OD1 no hydrogen 3.225 N/A MET 307.A N ILE 303.A O no hydrogen 2.908 N/A LEU 308.A N ARG 304.A O no hydrogen 2.918 N/A VAL 309.A N HIS 305.A O no hydrogen 2.966 N/A ALA 310.A N ILE 306.A O no hydrogen 2.911 N/A ASP 311.A N MET 307.A O no hydrogen 2.914 N/A MET 312.A N LEU 308.A O no hydrogen 2.930 N/A MET 313.A N VAL 309.A O no hydrogen 2.950 N/A THR 314.A N ALA 310.A O no hydrogen 3.214 N/A THR 314.A OG1 THR 314.A O no hydrogen 2.327 N/A ILE 318.A N ASP 316.A O no hydrogen 2.824 N/A ARG 320.A NE GLY 326.A O no hydrogen 3.115 N/A ILE 322.A N VAL 106.A O no hydrogen 3.469 N/A GLY 326.A N GLY 323.A O no hydrogen 3.357 N/A VAL 327.A N GLY 323.A O no hydrogen 2.963 N/A VAL 328.A N GLY 323.A O no hydrogen 3.047 N/A GLU 330.A N VAL 327.A O no hydrogen 3.255 N/A LYS 331.A N VAL 328.A O no hydrogen 3.087 N/A SER 333.A OG ASP 357.A OD1 no hydrogen 2.680 N/A SER 333.A OG GLU 364.A OE2 no hydrogen 2.671 N/A LEU 335.A N ASP 357.A OD2 no hydrogen 3.338 N/A ARG 337.A N SER 333.A O no hydrogen 2.929 N/A ARG 337.A NE LYS 331.A O no hydrogen 2.645 N/A ALA 338.A N VAL 334.A O no hydrogen 2.870 N/A ALA 338.A N LEU 335.A O no hydrogen 3.157 N/A PHE 340.A N ARG 337.A O no hydrogen 3.039 N/A GLN 345.A N THR 343.A OG1 no hydrogen 3.114 N/A LEU 347.A N VAL 344.A O no hydrogen 3.055 N/A GLU 349.A N GLN 345.A O no hydrogen 2.910 N/A ALA 350.A N HIS 346.A O no hydrogen 2.890 N/A ALA 351.A N LEU 347.A O no hydrogen 2.891 N/A GLU 352.A N PHE 348.A O no hydrogen 2.894 N/A LYS 353.A N GLU 349.A O no hydrogen 2.913 N/A GLY 354.A N ALA 351.A O no hydrogen 3.181 N/A GLU 355.A N ALA 350.A O no hydrogen 2.947 N/A LEU 359.A N ASP 357.A OD1 no hydrogen 3.489 N/A GLU 364.A N GLU 364.A OE1 no hydrogen 2.505 N/A ASN 365.A ND2 LEU 359.A O no hydrogen 2.869 N/A ASN 365.A ND2 GLY 361.A O no hydrogen 3.172 N/A VAL 366.A N VAL 362.A O no hydrogen 2.914 N/A LEU 367.A N ILE 363.A O no hydrogen 2.910 N/A ILE 368.A N GLU 364.A O no hydrogen 3.042 N/A GLY 369.A N ASN 365.A O no hydrogen 2.948 N/A GLN 370.A N ASN 365.A O no hydrogen 3.150 N/A VAL 374.A N VAL 372.A O no hydrogen 2.710 N/A GLY 375.A N GLY 62.A O no hydrogen 2.824 N/A GLY 377.A N VAL 374.A O no hydrogen 3.215 N/A MET 378.A N GLY 375.A O no hydrogen 3.056 N/A