Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8osx_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ALA 4.A N SER 1.A O no hydrogen 3.478 N/A TRP 5.A N SER 2.A O no hydrogen 3.084 N/A GLN 6.A N GLN 3.A O no hydrogen 3.005 N/A VAL 9.A N VAL 194.A O no hydrogen 2.818 N/A MET 11.A N ALA 192.A O no hydrogen 2.854 N/A TYR 15.A N PRO 12.A O no hydrogen 2.958 N/A LYS 16.A N PRO 12.A O no hydrogen 3.463 N/A LYS 16.A NZ ASN 13.A OD1 no hydrogen 2.850 N/A LYS 16.A NZ TRP 190.A O no hydrogen 2.731 N/A MET 17.A N LEU 14.A O no hydrogen 3.162 N/A GLN 18.A N TYR 15.A O no hydrogen 3.311 N/A GLN 18.A NE2 LEU 14.A O no hydrogen 2.961 N/A ARG 19.A NH1.A GLN 18.A O no hydrogen 2.884 N/A MET 20.A N ASN 227.A OD1 no hydrogen 3.020 N/A LYS 24.A NZ ASP 26.A OD1.A no hydrogen 2.852 N/A CYS 25.A N GLU 173.A OE2 no hydrogen 2.875 N/A CYS 25.A SG ASN 233.A OD1 no hydrogen 3.829 N/A ASP 26.A N.A ASN 233.A OD1 no hydrogen 2.838 N/A ASP 26.A N.B ASN 233.A OD1 no hydrogen 2.832 N/A GLN 28.A NE2 ASN 29.A OD1.B no hydrogen 2.878 N/A ASN 29.A ND2.A ALA 199.A O no hydrogen 2.917 N/A ASN 29.A ND2.B ILE 237.A O no hydrogen 2.732 N/A TYR 30.A N LEU 27.A O no hydrogen 3.221 N/A ASP 32.A N ASN 29.A O.A no hydrogen 3.000 N/A ASP 32.A N ASN 29.A O.B no hydrogen 3.200 N/A ILE 40.A N PRO 37.A O no hydrogen 3.038 N/A ALA 45.A N MET 41.A O no hydrogen 3.015 N/A LYS 46.A N MET 42.A O no hydrogen 2.738 N/A LYS 46.A NZ GLU 203.A OE1 no hydrogen 3.392 N/A LYS 46.A NZ GLU 203.A OE2 no hydrogen 2.809 N/A TYR 47.A N ASN 43.A O no hydrogen 2.988 N/A TYR 47.A OH HIS 69.A NE2 no hydrogen 2.703 N/A THR 48.A N VAL 44.A O no hydrogen 2.904 N/A THR 48.A OG1 VAL 44.A O no hydrogen 2.757 N/A GLN 49.A N ALA 45.A O no hydrogen 3.034 N/A GLN 49.A NE2 SER 240.A O no hydrogen 3.433 N/A GLN 49.A NE2 SER 243.A OG no hydrogen 2.930 N/A LEU 50.A N LYS 46.A O no hydrogen 2.954 N/A CYS 51.A N TYR 47.A O no hydrogen 2.913 N/A CYS 51.A SG TYR 47.A O no hydrogen 3.424 N/A GLN 52.A N THR 48.A O no hydrogen 2.801 N/A GLN 52.A NE2 SER 243.A O no hydrogen 2.981 N/A TYR 53.A N GLN 49.A O no hydrogen 2.941 N/A LEU 54.A N LEU 50.A O no hydrogen 2.859 N/A ASN 55.A N CYS 51.A O no hydrogen 2.869 N/A ASN 55.A ND2 PHE 250.A O no hydrogen 2.813 N/A THR 56.A N TYR 53.A O no hydrogen 2.881 N/A THR 56.A OG1 TYR 53.A O no hydrogen 2.642 N/A LEU 57.A N LEU 54.A O no hydrogen 3.121 N/A THR 58.A OG1 ASN 210.A OD1.A no hydrogen 2.809 N/A THR 58.A OG1 ASN 210.A OD1.B no hydrogen 2.777 N/A VAL 61.A N THR 257.A OG1 no hydrogen 2.743 N/A ARG 66.A N ASP 125.A OD2 no hydrogen 2.860 N/A ARG 66.A NH1 LYS 123.A O no hydrogen 2.881 N/A VAL 67.A N LEU 94.A O no hydrogen 2.883 N/A ILE 68.A N LEU 126.A O no hydrogen 3.131 N/A HIS 69.A N VAL 96.A O no hydrogen 2.807 N/A HIS 69.A ND1 THR 82.A OG1 no hydrogen 2.909 N/A HIS 69.A NE2 TYR 47.A OH no hydrogen 2.703 N/A PHE 70.A N ILE 128.A O no hydrogen 2.762 N/A ALA 72.A N SER 98.A O no hydrogen 2.900 N/A GLY 73.A N ASP 99.A OD2 no hydrogen 2.926 N/A SER 74.A OG VAL 78.A O no hydrogen 3.154 N/A LYS 76.A N SER 74.A OG no hydrogen 2.875 N/A GLY 77.A N SER 74.A O no hydrogen 2.874 N/A THR 82.A OG1 HIS 69.A ND1 no hydrogen 2.909 N/A THR 82.A OG1 ASP 97.A OD2 no hydrogen 2.684 N/A ALA 83.A N ALA 79.A O no hydrogen 3.154 N/A VAL 84.A N PRO 80.A O no hydrogen 3.076 N/A LEU 85.A N GLY 81.A O no hydrogen 2.925 N/A ARG 86.A N THR 82.A O no hydrogen 2.855 N/A ARG 86.A NH1 ASP 108.A OD1 no hydrogen 3.351 N/A ARG 86.A NH1 ASP 108.A OD2 no hydrogen 3.070 N/A ARG 86.A NH2 ASP 108.A OD1 no hydrogen 2.760 N/A GLN 87.A N ALA 83.A O no hydrogen 3.026 N/A TRP 88.A N VAL 84.A O no hydrogen 2.805 N/A TRP 88.A NE1 ASN 55.A OD1 no hydrogen 2.780 N/A LEU 89.A N LEU 85.A O no hydrogen 2.808 N/A THR 93.A N PRO 90.A O no hydrogen 3.010 N/A THR 93.A OG1 PRO 90.A O no hydrogen 2.713 N/A LEU 94.A N MET 65.A O no hydrogen 2.898 N/A LEU 95.A N ASP 108.A OD2 no hydrogen 2.822 N/A VAL 96.A N VAL 67.A O no hydrogen 3.003 N/A ASP 97.A N SER 109.A O no hydrogen 2.927 N/A SER 98.A N HIS 69.A O no hydrogen 2.910 N/A SER 98.A OG LEU 111.A O no hydrogen 2.713 N/A ASP 99.A N LEU 111.A O no hydrogen 3.267 N/A ASN 101.A N ASP 99.A OD1 no hydrogen 3.033 N/A VAL 104.A N GLY 77.A O no hydrogen 2.882 N/A SER 105.A OG ASP 97.A OD1 no hydrogen 3.523 N/A SER 105.A OG ASP 97.A OD2 no hydrogen 2.610 N/A ALA 107.A N SER 105.A OG no hydrogen 2.765 N/A ASP 108.A N LEU 95.A O no hydrogen 2.754 N/A THR 110.A OG1 ASP 97.A OD1 no hydrogen 2.698 N/A LEU 111.A N ASP 97.A O no hydrogen 2.995 N/A GLY 113.A N ASP 99.A O no hydrogen 2.772 N/A ALA 116.A N ASP 114.A OD2 no hydrogen 2.990 N/A THR 117.A N ASP 114.A O no hydrogen 2.907 N/A THR 117.A OG1 ASP 114.A O no hydrogen 2.628 N/A THR 117.A OG1 SER 292.A OG no hydrogen 3.294 N/A VAL 118.A N CYS 115.A O no hydrogen 2.915 N/A HIS 119.A N SER 291.A O no hydrogen 2.841 N/A THR 120.A OG1 ASN 122.A O.A no hydrogen 2.967 N/A THR 120.A OG1 ASN 122.A O.B no hydrogen 3.002 N/A ALA 121.A N VAL 289.A O no hydrogen 3.062 N/A ASN 122.A ND2.A LYS 123.A O no hydrogen 3.101 N/A ASN 122.A ND2.B ARG 287.A O no hydrogen 2.359 N/A TRP 124.A N LYS 160.A O no hydrogen 2.774 N/A TRP 124.A NE1 THR 120.A OG1 no hydrogen 3.048 N/A ASP 125.A N ARG 66.A O no hydrogen 2.851 N/A LEU 126.A N ARG 66.A O no hydrogen 3.319 N/A ILE 127.A N SER 166.A O no hydrogen 3.083 N/A ILE 128.A N ILE 68.A O no hydrogen 2.941 N/A SER 129.A N ALA 168.A O no hydrogen 2.967 N/A ASP 130.A N PHE 70.A O no hydrogen 2.848 N/A MET 131.A N SER 129.A OG no hydrogen 3.210 N/A LYS 135.A N ASP 133.A OD1 no hydrogen 2.947 N/A THR 136.A N ASP 133.A O no hydrogen 2.917 N/A THR 136.A OG1 ASP 133.A O no hydrogen 2.888 N/A LYS 137.A N PRO 134.A O no hydrogen 3.111 N/A LYS 137.A NZ TYR 132.A OH no hydrogen 3.254 N/A THR 140.A N ASN 138.A OD1 no hydrogen 3.024 N/A THR 140.A OG1 ASN 138.A OD1 no hydrogen 2.695 N/A ASN 143.A ND2 GLU 173.A O no hydrogen 2.890 N/A LYS 146.A N TRP 176.A O no hydrogen 2.802 N/A LYS 146.A NZ ASP 144.A O no hydrogen 2.593 N/A LYS 146.A NZ HIS 174.A O no hydrogen 2.934 N/A PHE 150.A N GLU 147.A O.A no hydrogen 2.896 N/A PHE 150.A N GLU 147.A O.B no hydrogen 2.886 N/A THR 151.A N GLY 148.A O no hydrogen 3.010 N/A THR 151.A OG1 GLU 147.A OE1.A no hydrogen 2.546 N/A TYR 152.A OH VAL 118.A O no hydrogen 2.832 N/A ILE 153.A N PHE 149.A O no hydrogen 2.926 N/A CYS 154.A N PHE 150.A O no hydrogen 2.981 N/A CYS 154.A SG PHE 150.A O no hydrogen 3.447 N/A CYS 154.A SG ASN 177.A OD1 no hydrogen 3.705 N/A GLY 155.A N THR 151.A O no hydrogen 3.159 N/A PHE 156.A N TYR 152.A O no hydrogen 2.736 N/A ILE 157.A N ILE 153.A O no hydrogen 2.912 N/A GLN 158.A N CYS 154.A O no hydrogen 3.066 N/A GLN 159.A N GLY 155.A O no hydrogen 2.881 N/A LYS 160.A N PHE 156.A O no hydrogen 2.757 N/A LYS 160.A NZ THR 120.A O no hydrogen 2.890 N/A LYS 160.A NZ ALA 121.A O no hydrogen 3.351 N/A LEU 161.A N ILE 157.A O no hydrogen 3.228 N/A ALA 162.A N TRP 124.A O no hydrogen 2.823 N/A LEU 163.A N ILE 282.A O no hydrogen 3.265 N/A GLY 164.A N TYR 211.A O no hydrogen 2.710 N/A GLY 165.A N ALA 162.A O no hydrogen 2.873 N/A SER 166.A N ASP 125.A O no hydrogen 3.129 N/A VAL 167.A N GLY 208.A O no hydrogen 2.884 N/A ALA 168.A N ILE 127.A O no hydrogen 2.968 N/A ILE 169.A N LEU 206.A O no hydrogen 2.920 N/A LYS 170.A N SER 129.A O no hydrogen 2.877 N/A LYS 170.A NZ GLU 203.A OE2 no hydrogen 2.556 N/A ILE 171.A N ALA 204.A O no hydrogen 2.829 N/A THR 172.A N SER 175.A O no hydrogen 2.882 N/A GLU 173.A N SER 202.A OG no hydrogen 2.914 N/A SER 175.A N THR 172.A OG1 no hydrogen 2.872 N/A TRP 176.A NE1 ASN 143.A OD1 no hydrogen 2.914 N/A ASN 177.A ND2 LYS 146.A O no hydrogen 2.660 N/A ALA 178.A N SER 145.A OG no hydrogen 2.871 N/A LEU 180.A N ASN 177.A OD1 no hydrogen 2.845 N/A TYR 181.A N ASN 177.A O no hydrogen 3.424 N/A TYR 181.A OH HIS 225.A ND1 no hydrogen 2.754 N/A LYS 182.A N ALA 178.A O no hydrogen 2.977 N/A LEU 183.A N ASP 179.A O no hydrogen 2.806 N/A MET 184.A N LEU 180.A O no hydrogen 3.077 N/A GLY 185.A N LYS 182.A O no hydrogen 3.084 N/A HIS 186.A N LEU 183.A O no hydrogen 2.821 N/A PHE 187.A N MET 184.A O no hydrogen 3.326 N/A ALA 188.A N ASN 210.A O.A no hydrogen 2.915 N/A ALA 188.A N ASN 210.A O.B no hydrogen 2.940 N/A TRP 189.A N CYS 209.A O no hydrogen 3.338 N/A THR 191.A N ILE 207.A O no hydrogen 2.990 N/A THR 191.A OG1 MET 11.A O no hydrogen 3.498 N/A PHE 193.A N PHE 205.A O no hydrogen 2.892 N/A VAL 194.A N VAL 9.A O no hydrogen 2.903 N/A ASN 196.A N PRO 7.A O no hydrogen 2.965 N/A ASN 196.A ND2 GLN 3.A O no hydrogen 2.849 N/A ASN 196.A ND2 GLN 6.A O no hydrogen 2.770 N/A VAL 197.A N GLN 49.A OE1 no hydrogen 2.856 N/A ASN 198.A N THR 195.A O no hydrogen 3.266 N/A ASN 198.A N THR 195.A OG1 no hydrogen 3.218 N/A ASN 198.A ND2 GLU 203.A OE1 no hydrogen 2.920 N/A SER 200.A OG ASP 32.A O no hydrogen 3.164 N/A SER 201.A N ASN 198.A O no hydrogen 2.959 N/A GLU 203.A N SER 201.A OG no hydrogen 2.989 N/A ALA 204.A N ILE 171.A O no hydrogen 2.983 N/A PHE 205.A N PHE 193.A O no hydrogen 2.808 N/A LEU 206.A N ILE 169.A O no hydrogen 2.858 N/A ILE 207.A N THR 191.A O no hydrogen 2.900 N/A GLY 208.A N VAL 167.A O no hydrogen 3.021 N/A CYS 209.A N TRP 189.A O no hydrogen 2.756 N/A CYS 209.A SG THR 58.A OG1 no hydrogen 3.721 N/A CYS 209.A SG ASN 210.A OD1.A no hydrogen 3.173 N/A CYS 209.A SG ASN 210.A OD1.B no hydrogen 3.601 N/A ASN 210.A N.A SER 166.A OG no hydrogen 2.997 N/A ASN 210.A N.B SER 166.A OG no hydrogen 2.989 N/A ASN 210.A ND2.A THR 58.A O no hydrogen 2.767 N/A ASN 210.A ND2.A GLY 164.A O no hydrogen 3.533 N/A ASN 210.A ND2.B THR 58.A O no hydrogen 2.986 N/A ASN 210.A ND2.B GLY 164.A O no hydrogen 3.026 N/A TYR 211.A N GLY 165.A O no hydrogen 2.667 N/A LEU 212.A N HIS 186.A O no hydrogen 2.825 N/A ARG 216.A N GLY 185.A O no hydrogen 2.828 N/A ARG 216.A NE PHE 187.A O no hydrogen 3.088 N/A GLU 217.A N GLY 185.A O no hydrogen 3.214 N/A VAL 223.A N ASP 220.A OD1 no hydrogen 3.099 N/A MET 224.A N ASP 220.A O no hydrogen 2.828 N/A HIS 225.A N GLY 221.A O no hydrogen 3.036 N/A HIS 225.A ND1 TYR 181.A OH no hydrogen 2.754 N/A HIS 225.A NE2 GLU 173.A O no hydrogen 2.827 N/A ALA 226.A N TYR 222.A O no hydrogen 3.171 N/A ASN 227.A N VAL 223.A O no hydrogen 2.847 N/A ASN 227.A ND2 LYS 16.A O no hydrogen 3.214 N/A ASN 227.A ND2 GLN 18.A O no hydrogen 2.877 N/A TYR 228.A N MET 224.A O no hydrogen 2.885 N/A TYR 228.A OH SER 202.A O no hydrogen 2.569 N/A ILE 229.A N HIS 225.A O no hydrogen 2.950 N/A PHE 230.A N ALA 226.A O no hydrogen 2.858 N/A TRP 231.A N ASN 227.A O no hydrogen 3.004 N/A ARG 232.A N TYR 228.A O no hydrogen 2.913 N/A ARG 232.A NH1 SER 201.A O no hydrogen 3.008 N/A ARG 232.A NH1 TYR 228.A OH no hydrogen 2.939 N/A ARG 232.A NH2 SER 201.A O no hydrogen 3.205 N/A ASN 233.A N ILE 229.A O no hydrogen 2.723 N/A ASN 233.A ND2 LYS 24.A O no hydrogen 2.920 N/A THR 234.A N PHE 230.A O no hydrogen 3.119 N/A THR 234.A N TRP 231.A O no hydrogen 3.142 N/A THR 234.A OG1 PHE 230.A O no hydrogen 2.985 N/A THR 234.A OG1 TRP 231.A O no hydrogen 3.515 N/A ASN 235.A ND2 TYR 15.A OH no hydrogen 2.848 N/A ASN 235.A ND2 TRP 231.A O no hydrogen 3.125 N/A SER 240.A N ASN 196.A O no hydrogen 2.972 N/A SER 240.A OG ALA 4.A O no hydrogen 2.474 N/A SER 241.A OG.A THR 35.A O.A no hydrogen 2.822 N/A SER 241.A OG.A THR 35.A O.B no hydrogen 2.797 N/A SER 241.A OG.B THR 35.A O.A no hydrogen 2.858 N/A SER 241.A OG.B THR 35.A O.B no hydrogen 2.817 N/A TYR 242.A N.B SER 240.A OG no hydrogen 3.197 N/A TYR 242.A O.B SER 241.A O.A no hydrogen 3.347 N/A TYR 242.A O.B SER 241.A O.B no hydrogen 3.186 N/A TYR 242.A O.C SER 241.A O.A no hydrogen 3.635 N/A TYR 242.A O.C SER 241.A O.B no hydrogen 3.469 N/A SER 243.A OG GLN 52.A OE1 no hydrogen 2.758 N/A LEU 244.A N SER 241.A O.A no hydrogen 3.103 N/A LEU 244.A N SER 241.A O.B no hydrogen 2.944 N/A PHE 245.A N TYR 242.A O.B no hydrogen 2.983 N/A PHE 245.A N TYR 242.A O.C no hydrogen 3.340 N/A ASP 246.A N SER 243.A O no hydrogen 3.493 N/A SER 248.A N ASP 246.A OD1 no hydrogen 3.130 N/A SER 248.A OG ASP 246.A OD1 no hydrogen 2.768 N/A LYS 249.A NZ SER 248.A OG no hydrogen 3.038 N/A PHE 250.A N MET 247.A O no hydrogen 3.076 N/A LEU 252.A N TRP 88.A O no hydrogen 2.857 N/A ARG 255.A NH1 LEU 59.A O no hydrogen 2.781 N/A THR 257.A N VAL 61.A O no hydrogen 3.148 N/A MET 260.A N ILE 281.A O no hydrogen 2.977 N/A SER 261.A OG GLU 284.A OE2 no hydrogen 2.796 N/A LYS 263.A N GLN 266.A OE1 no hydrogen 3.234 N/A GLN 266.A N LYS 263.A O no hydrogen 2.730 N/A ILE 271.A N ASN 268.A OD1 no hydrogen 2.815 N/A LEU 272.A N ASN 268.A O no hydrogen 2.784 N/A SER 273.A N ASP 269.A O no hydrogen 2.788 N/A LEU 274.A N MET 270.A O no hydrogen 3.076 N/A LEU 275.A N ILE 271.A O no hydrogen 2.816 N/A SER 276.A N LEU 272.A O no hydrogen 3.006 N/A SER 276.A OG LEU 272.A O no hydrogen 3.004 N/A LYS 277.A N SER 273.A O no hydrogen 3.263 N/A LYS 277.A N LEU 274.A O no hydrogen 3.239 N/A LYS 277.A NZ SER 273.A OG no hydrogen 3.064 N/A GLY 278.A N LEU 275.A O no hydrogen 3.125 N/A ARG 279.A N.A LEU 274.A O no hydrogen 3.081 N/A ARG 279.A N.B LEU 274.A O no hydrogen 3.098 N/A ILE 281.A N ALA 258.A O no hydrogen 2.915 N/A ILE 282.A N LEU 163.A O no hydrogen 3.007 N/A ARG 283.A N MET 260.A O no hydrogen 3.043 N/A ARG 283.A NE ASP 125.A OD1 no hydrogen 2.656 N/A ARG 283.A NH1 GLU 284.A O no hydrogen 3.125 N/A ARG 283.A NH1 ASN 285.A OD1 no hydrogen 2.890 N/A ARG 283.A NH2 ASP 125.A OD1 no hydrogen 3.315 N/A ARG 283.A NH2 ASP 125.A OD2 no hydrogen 2.794 N/A VAL 289.A N ASN 122.A OD1.A no hydrogen 3.336 N/A VAL 289.A N ASN 122.A OD1.B no hydrogen 3.120 N/A SER 291.A N HIS 119.A O no hydrogen 2.872 N/A SER 292.A OG THR 117.A OG1 no hydrogen 3.294 N/A ASP 293.A N THR 117.A O no hydrogen 2.790 N/A ASN 300.A N ASN 298.A OD1 no hydrogen 3.046 N/A ASN 300.A ND2 ASN 298.A OD1 no hydrogen 2.777 N/A