Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8otz_AV.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): SER 1.A N GLU 2.A OE1 no hydrogen 3.164 N/A PHE 4.A N PHE 25.A O no hydrogen 2.946 N/A PHE 6.A N LEU 23.A O no hydrogen 2.782 N/A ILE 7.A N ASP 74.A O no hydrogen 2.793 N/A ALA 8.A N TYR 21.A O no hydrogen 3.210 N/A TRP 10.A N ARG 19.A O no hydrogen 2.873 N/A ALA 15.A N ASP 12.A OD2 no hydrogen 3.144 N/A LEU 17.A N ALA 15.A O no hydrogen 2.677 N/A ARG 19.A N TRP 10.A O no hydrogen 3.005 N/A ARG 20.A NH2 GLU 9.A OE2 no hydrogen 2.754 N/A TYR 21.A N ALA 8.A O no hydrogen 3.105 N/A LEU 23.A N PHE 6.A O no hydrogen 2.752 N/A LEU 24.A N GLU 33.A O no hydrogen 2.835 N/A PHE 25.A N PHE 4.A O no hydrogen 2.728 N/A TYR 26.A N SER 31.A O no hydrogen 2.861 N/A GLY 30.A N TYR 26.A O no hydrogen 3.117 N/A SER 31.A N ASP 29.A OD1 no hydrogen 2.854 N/A SER 31.A OG ASP 29.A OD1 no hydrogen 2.927 N/A VAL 32.A N THR 47.A O no hydrogen 3.140 N/A GLU 33.A N LEU 24.A O no hydrogen 3.061 N/A MET 34.A N LEU 44.A O no hydrogen 3.240 N/A HIS 35.A N GLU 22.A O no hydrogen 3.221 N/A ASP 36.A N ARG 41.A O no hydrogen 2.970 N/A PHE 43.A N MET 34.A O no hydrogen 2.816 N/A LEU 44.A N MET 34.A O no hydrogen 2.977 N/A LYS 45.A NZ PHE 43.A O no hydrogen 3.540 N/A ARG 46.A NH2 ASP 29.A OD2 no hydrogen 3.162 N/A THR 47.A OG1 LYS 45.A O no hydrogen 3.268 N/A LYS 48.A NZ ASP 29.A O no hydrogen 2.367 N/A TYR 49.A N GLY 30.A O no hydrogen 3.314 N/A TYR 49.A OH ASN 64.A O no hydrogen 3.381 N/A GLU 50.A N GLU 50.A OE1 no hydrogen 2.786 N/A HIS 53.A N ASP 56.A OD2 no hydrogen 2.847 N/A LEU 57.A N LEU 54.A O no hydrogen 3.332 N/A GLY 60.A N LEU 72.A O no hydrogen 3.121 N/A ASN 61.A N PHE 58.A O no hydrogen 3.122 N/A ASN 61.A ND2 ASP 56.A O no hydrogen 2.343 N/A VAL 63.A N LEU 70.A O no hydrogen 3.181 N/A ILE 65.A N ARG 68.A O no hydrogen 3.148 N/A PHE 66.A N TYR 49.A OH no hydrogen 3.008 N/A SER 67.A OG PHE 66.A O no hydrogen 2.548 N/A ARG 68.A N ILE 65.A O no hydrogen 3.009 N/A VAL 71.A N GLU 9.A O no hydrogen 3.244 N/A LEU 72.A N ASN 61.A O no hydrogen 3.056 N/A LEU 73.A N ILE 7.A O no hydrogen 3.146 N/A GLY 76.A N VAL 5.A O no hydrogen 2.639 N/A ARG 82.A N GLN 78.A O no hydrogen 2.958 N/A GLN 83.A N TYR 79.A O no hydrogen 2.885 N/A LEU 84.A N THR 80.A O no hydrogen 2.888 N/A SER 86.A OG ARG 82.A O no hydrogen 2.478 N/A LYS 88.A NZ ASP 163.A OD1 no hydrogen 2.361 N/A GLU 89.A N ARG 162.A O no hydrogen 3.224 N/A THR 91.A N ILE 160.A O no hydrogen 3.413 N/A ALA 93.A N MET 158.A O no hydrogen 3.337 N/A LEU 94.A N HIS 203.A O no hydrogen 3.052 N/A ILE 95.A N ILE 156.A O no hydrogen 2.929 N/A LYS 96.A N ALA 201.A O no hydrogen 3.467 N/A LYS 102.A N ALA 99.A O no hydrogen 3.175 N/A ALA 103.A N VAL 100.A O no hydrogen 3.190 N/A GLU 105.A N GLU 105.A OE1 no hydrogen 2.620 N/A ILE 107.A N ALA 103.A O no hydrogen 2.942 N/A GLU 108.A N GLY 104.A O no hydrogen 2.898 N/A ILE 109.A N GLU 105.A O no hydrogen 2.904 N/A ILE 110.A N ILE 106.A O no hydrogen 2.914 N/A ASN 111.A N ILE 107.A O no hydrogen 2.926 N/A LYS 112.A N GLU 108.A O no hydrogen 2.932 N/A ALA 113.A N ILE 109.A O no hydrogen 3.218 N/A GLY 114.A N ASN 111.A O no hydrogen 3.210 N/A THR 116.A N LEU 161.A O no hydrogen 3.040 N/A THR 116.A OG1 GLU 55.A OE1 no hydrogen 3.106 N/A THR 118.A N GLU 159.A O no hydrogen 3.127 N/A LYS 121.A N ALA 157.A O no hydrogen 3.259 N/A LYS 121.A NZ ALA 222.A O no hydrogen 3.217 N/A MET 122.A N MET 263.A O no hydrogen 3.273 N/A MET 123.A N ILE 155.A O no hydrogen 3.112 N/A LYS 128.A N SER 126.A OG no hydrogen 3.149 N/A ALA 130.A N SER 126.A O no hydrogen 3.463 N/A THR 131.A OG1 LYS 128.A O no hydrogen 2.553 N/A ASP 132.A N LYS 128.A O no hydrogen 2.932 N/A PHE 133.A N ALA 130.A O no hydrogen 3.152 N/A HIS 134.A N ALA 130.A O no hydrogen 2.955 N/A GLN 138.A N ASP 136.A O no hydrogen 2.818 N/A ILE 147.A N LEU 143.A O no hydrogen 2.840 N/A GLN 148.A N ASN 144.A O no hydrogen 2.915 N/A PHE 149.A N GLU 145.A O no hydrogen 2.865 N/A ILE 150.A N LEU 146.A O no hydrogen 2.947 N/A THR 151.A N ILE 147.A O no hydrogen 3.210 N/A THR 151.A OG1 ILE 147.A O no hydrogen 2.455 N/A THR 151.A OG1 GLN 148.A O no hydrogen 3.450 N/A SER 152.A OG PHE 149.A O no hydrogen 2.816 N/A ILE 156.A N ILE 95.A O no hydrogen 3.124 N/A MET 158.A N ALA 93.A O no hydrogen 3.000 N/A GLU 159.A N LYS 119.A O no hydrogen 2.744 N/A ILE 160.A N THR 91.A O no hydrogen 3.463 N/A LEU 161.A N THR 116.A O no hydrogen 2.905 N/A ARG 162.A NE ALA 113.A O no hydrogen 3.117 N/A ARG 162.A NH1 ASP 163.A O no hydrogen 3.115 N/A ARG 162.A NH2 ALA 113.A O no hydrogen 3.201 N/A ASP 164.A N LYS 87.A O no hydrogen 2.783 N/A VAL 166.A N GLU 89.A OE1 no hydrogen 2.967 N/A GLU 168.A N ASP 164.A O no hydrogen 3.268 N/A TRP 169.A N ALA 165.A O no hydrogen 2.882 N/A LYS 170.A N VAL 166.A O no hydrogen 2.960 N/A LYS 170.A NZ GLY 204.A O no hydrogen 2.460 N/A ARG 171.A N CYS 167.A O no hydrogen 2.886 N/A ARG 171.A NH2 GLU 168.A OE2 no hydrogen 2.775 N/A LEU 172.A N GLU 168.A O no hydrogen 2.897 N/A LEU 173.A N TRP 169.A O no hydrogen 2.913 N/A GLY 174.A N LYS 170.A O no hydrogen 3.069 N/A SER 178.A OG ARG 190.A O no hydrogen 3.139 N/A SER 178.A OG GLY 194.A O no hydrogen 3.261 N/A SER 178.A OG THR 195.A O no hydrogen 2.684 N/A THR 183.A OG1 LEU 180.A O no hydrogen 2.449 N/A ASP 184.A N LEU 180.A O no hydrogen 2.963 N/A ALA 185.A N ALA 181.A O no hydrogen 2.790 N/A GLU 187.A N GLU 187.A OE1 no hydrogen 2.779 N/A SER 188.A N ALA 185.A O no hydrogen 3.249 N/A SER 188.A OG ALA 185.A O no hydrogen 2.744 N/A ILE 189.A N LEU 172.A O no hydrogen 3.032 N/A ARG 190.A N LEU 173.A O no hydrogen 3.105 N/A ARG 190.A NE ALA 202.A O no hydrogen 3.218 N/A ARG 190.A NH2 ALA 202.A O no hydrogen 2.885 N/A ALA 191.A N SER 188.A O no hydrogen 2.845 N/A LEU 192.A N SER 188.A O no hydrogen 3.362 N/A PHE 193.A N ILE 189.A O no hydrogen 3.247 N/A LYS 199.A NZ THR 195.A OG1 no hydrogen 2.700 N/A ASN 200.A N ILE 198.A O no hydrogen 3.283 N/A HIS 203.A N LEU 94.A O no hydrogen 3.146 N/A SER 207.A N ASP 206.A OD1 no hydrogen 2.746 N/A CYS 210.A N SER 207.A OG no hydrogen 3.064 N/A ALA 212.A N PHE 208.A O no hydrogen 2.903 N/A ARG 213.A N ALA 209.A O no hydrogen 2.931 N/A ARG 213.A NH1 ASP 132.A O no hydrogen 2.567 N/A ARG 213.A NH2 PHE 133.A O no hydrogen 3.173 N/A GLU 214.A N CYS 210.A O no hydrogen 2.924 N/A MET 215.A N ALA 211.A O no hydrogen 2.911 N/A GLU 216.A N ALA 212.A O no hydrogen 2.930 N/A LEU 217.A N GLU 214.A O no hydrogen 3.284 N/A PHE 218.A N GLU 214.A O no hydrogen 2.926 N/A PHE 219.A N MET 215.A O no hydrogen 3.127 N/A THR 224.A N ASN 223.A OD1 no hydrogen 3.026 N/A THR 224.A OG1 MET 122.A O no hydrogen 3.363 N/A THR 224.A OG1 SER 261.A O no hydrogen 3.025 N/A LYS 226.A N GLU 303.A OE1 no hydrogen 3.283 N/A PHE 227.A N GLU 303.A OE2 no hydrogen 3.371 N/A THR 228.A OG1 THR 231.A OG1 no hydrogen 3.161 N/A THR 228.A OG1 GLN 305.A OE1 no hydrogen 2.488 N/A CYS 230.A SG GLN 306.A O no hydrogen 3.193 N/A THR 231.A N THR 228.A O no hydrogen 3.165 N/A THR 231.A OG1 THR 228.A OG1 no hydrogen 3.161 N/A THR 231.A OG1 GLU 303.A OE2 no hydrogen 2.693 N/A THR 232.A OG1 THR 232.A O no hydrogen 2.519 N/A THR 232.A OG1 PRO 352.A O no hydrogen 2.697 N/A CYS 233.A SG GLN 306.A OE1 no hydrogen 3.595 N/A CYS 234.A SG MET 302.A O no hydrogen 3.756 N/A ILE 235.A N MET 302.A O no hydrogen 3.085 N/A HIS 239.A NE2 GLN 343.A O no hydrogen 3.081 N/A SER 242.A N HIS 239.A O no hydrogen 3.079 N/A LEU 245.A N ALA 240.A O no hydrogen 2.639 N/A ILE 249.A N LEU 245.A O no hydrogen 3.243 N/A LEU 250.A N LEU 246.A O no hydrogen 2.947 N/A MET 251.A N GLY 247.A O no hydrogen 2.945 N/A THR 252.A N LYS 248.A O no hydrogen 2.944 N/A ILE 253.A N ILE 249.A O no hydrogen 2.898 N/A ARG 254.A N LEU 250.A O no hydrogen 2.975 N/A ARG 254.A NH1 SER 101.A O no hydrogen 3.255 N/A ARG 254.A NH1 GLU 105.A OE1 no hydrogen 3.568 N/A ARG 254.A NH1 GLU 105.A OE2 no hydrogen 3.326 N/A ARG 254.A NH2 GLU 105.A OE2 no hydrogen 3.483 N/A ASP 255.A N MET 251.A O no hydrogen 3.239 N/A SER 261.A N GLU 303.A O no hydrogen 3.182 N/A GLN 264.A N ALA 301.A O no hydrogen 2.967 N/A MET 265.A N LEU 120.A O no hydrogen 2.491 N/A PHE 266.A N CYS 299.A O no hydrogen 2.695 N/A ASP 269.A N ASP 269.A OD1 no hydrogen 2.445 N/A ARG 270.A NE GLU 274.A OE2 no hydrogen 3.039 N/A ARG 270.A NH2 GLU 274.A OE2 no hydrogen 2.385 N/A GLU 274.A N ARG 270.A O no hydrogen 2.992 N/A GLU 275.A N ASN 272.A O no hydrogen 3.240 N/A PHE 276.A N ASN 272.A O no hydrogen 3.183 N/A GLU 278.A N GLU 278.A OE1 no hydrogen 2.575 N/A TYR 280.A N TYR 277.A O no hydrogen 3.114 N/A TYR 280.A OH ASP 350.A OD1 no hydrogen 2.569 N/A TYR 280.A OH ASP 350.A OD2 no hydrogen 3.336 N/A MET 290.A N GLU 286.A O no hydrogen 3.315 N/A VAL 291.A N TYR 287.A O no hydrogen 2.914 N/A THR 292.A N ASN 288.A O no hydrogen 2.894 N/A THR 292.A OG1 ASN 288.A O no hydrogen 3.361 N/A THR 292.A OG1 GLU 289.A O no hydrogen 2.559 N/A GLU 293.A N GLU 289.A O no hydrogen 2.905 N/A MET 294.A N MET 290.A O no hydrogen 2.988 N/A SER 296.A N GLU 293.A O no hydrogen 3.271 N/A SER 296.A OG THR 292.A O no hydrogen 2.797 N/A SER 296.A OG GLU 293.A O no hydrogen 3.086 N/A CYS 299.A N PHE 266.A O no hydrogen 2.845 N/A CYS 299.A SG PHE 266.A O no hydrogen 3.952 N/A ALA 301.A N GLN 264.A O no hydrogen 2.776 N/A MET 302.A N ILE 235.A O no hydrogen 3.061 N/A GLU 303.A N ALA 262.A O no hydrogen 3.114 N/A ILE 304.A N CYS 233.A O no hydrogen 3.477 N/A GLN 305.A N GLU 259.A O no hydrogen 3.027 N/A GLN 305.A NE2 SER 261.A OG no hydrogen 3.109 N/A THR 307.A OG1 GLY 257.A O no hydrogen 2.617 N/A PHE 313.A N GLN 306.A OE1 no hydrogen 3.128 N/A GLU 315.A N THR 312.A O no hydrogen 3.155 N/A GLU 315.A N GLU 315.A OE1 no hydrogen 2.726 N/A PHE 316.A N THR 312.A O no hydrogen 3.154 N/A CYS 317.A N PHE 313.A O no hydrogen 2.878 N/A CYS 317.A SG PHE 313.A O no hydrogen 3.254 N/A GLY 318.A N ARG 314.A O no hydrogen 3.295 N/A ALA 325.A N ASP 321.A O no hydrogen 3.251 N/A ARG 326.A N PRO 322.A O no hydrogen 2.894 N/A ARG 326.A NE ALA 335.A O no hydrogen 2.591 N/A HIS 327.A N GLU 323.A O no hydrogen 2.994 N/A ARG 329.A N ALA 325.A O no hydrogen 3.235 N/A THR 332.A N ARG 329.A O no hydrogen 3.146 N/A THR 332.A OG1 ARG 329.A O no hydrogen 2.578 N/A LEU 333.A N PHE 316.A O no hydrogen 3.058 N/A ARG 334.A N CYS 317.A O no hydrogen 3.242 N/A ARG 334.A NE VAL 346.A O no hydrogen 2.780 N/A ARG 334.A NH2 VAL 346.A O no hydrogen 2.925 N/A ILE 336.A N LEU 333.A O no hydrogen 3.180 N/A PHE 337.A N LEU 333.A O no hydrogen 2.982 N/A GLY 338.A N ARG 334.A O no hydrogen 3.136 N/A LYS 339.A NZ GLU 243.A OE2 no hydrogen 3.564 N/A THR 340.A OG1 LYS 339.A O no hydrogen 3.022 N/A LYS 341.A NZ GLU 286.A OE1 no hydrogen 2.350 N/A ASN 344.A ND2 VAL 346.A O no hydrogen 2.718 N/A HIS 347.A N VAL 236.A O no hydrogen 3.407 N/A THR 349.A OG1 THR 232.A O no hydrogen 2.677 N/A GLU 353.A N GLU 353.A OE1 no hydrogen 2.440 N/A ASP 354.A N LEU 351.A O no hydrogen 3.153 N/A GLU 358.A N ASP 354.A O no hydrogen 3.132 N/A VAL 359.A N GLY 355.A O no hydrogen 2.970 N/A GLN 360.A N LEU 356.A O no hydrogen 2.872 N/A TYR 361.A N LEU 357.A O no hydrogen 2.892 N/A TYR 361.A OH ASN 272.A O no hydrogen 3.146 N/A PHE 362.A N GLU 358.A O no hydrogen 2.956 N/A PHE 363.A N VAL 359.A O no hydrogen 2.946 N/A PHE 363.A N GLN 360.A O no hydrogen 3.350 N/A LYS 364.A N GLN 360.A O no hydrogen 2.872 N/A