Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8p2i_C.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): SER 2.A OG SER 4.A OG no hydrogen 3.059 N/A SER 2.A OG THR 5.A OG1 no hydrogen 2.965 N/A SER 4.A OG SER 2.A OG no hydrogen 3.059 N/A THR 5.A N SER 2.A OG no hydrogen 3.281 N/A THR 5.A OG1 SER 2.A O no hydrogen 2.405 N/A THR 5.A OG1 SER 2.A OG no hydrogen 2.965 N/A ILE 6.A N SER 2.A O no hydrogen 3.287 N/A LYS 7.A N LEU 3.A O no hydrogen 2.908 N/A SER 8.A N SER 4.A O no hydrogen 2.900 N/A SER 8.A OG THR 5.A O no hydrogen 2.771 N/A LEU 9.A N THR 5.A O no hydrogen 2.887 N/A ILE 10.A N ILE 6.A O no hydrogen 2.931 N/A GLU 11.A N LYS 7.A O no hydrogen 3.322 N/A LYS 12.A N LEU 9.A O no hydrogen 3.137 N/A LYS 13.A N LEU 9.A O no hydrogen 3.430 N/A LYS 13.A NZ ASP 48.A OD1 no hydrogen 3.112 N/A LYS 13.A NZ ASP 48.A OD2 no hydrogen 2.920 N/A GLY 14.A N ILE 10.A O no hydrogen 3.130 N/A LEU 17.A N GLY 14.A O no hydrogen 3.249 N/A LYS 22.A N PRO 18.A O no hydrogen 2.993 N/A LYS 22.A NZ LEU 17.A O no hydrogen 2.401 N/A LYS 22.A NZ PRO 18.A O no hydrogen 2.714 N/A SER 23.A N GLU 19.A O no hydrogen 2.980 N/A SER 23.A OG ASN 20.A O no hydrogen 2.937 N/A GLU 24.A N ASN 20.A O no hydrogen 2.881 N/A LEU 25.A N VAL 21.A O no hydrogen 2.880 N/A TYR 26.A N LYS 22.A O no hydrogen 3.211 N/A GLU 27.A N SER 23.A O no hydrogen 2.963 N/A LYS 28.A N GLU 24.A O no hydrogen 2.912 N/A LYS 28.A NZ GLU 24.A OE1 no hydrogen 3.345 N/A LYS 28.A NZ GLU 24.A OE2 no hydrogen 2.449 N/A LEU 29.A N LEU 25.A O no hydrogen 2.895 N/A LYS 30.A N TYR 26.A O no hydrogen 2.913 N/A LYS 30.A NZ GLU 27.A OE1 no hydrogen 3.483 N/A LYS 30.A NZ GLU 27.A OE2 no hydrogen 3.525 N/A LYS 31.A N GLU 27.A O no hydrogen 2.940 N/A TYR 32.A N LYS 28.A O no hydrogen 2.898 N/A ASN 33.A N LEU 29.A O no hydrogen 2.898 N/A TYR 36.A N TYR 32.A O no hydrogen 2.905 N/A LYS 37.A NZ ASN 33.A O no hydrogen 3.123 N/A LYS 37.A NZ GLU 34.A O no hydrogen 2.417 N/A LEU 38.A N ASN 33.A OD1 no hydrogen 3.326 N/A THR 39.A N GLU 42.A OE1 no hydrogen 2.714 N/A LYS 40.A NZ GLU 44.A OE2 no hydrogen 2.514 N/A GLU 42.A N THR 39.A OG1 no hydrogen 3.198 N/A ILE 43.A N THR 39.A O no hydrogen 3.061 N/A GLU 44.A N LYS 40.A O no hydrogen 2.966 N/A ALA 45.A N ALA 41.A O no hydrogen 2.882 N/A ILE 46.A N GLU 42.A O no hydrogen 2.899 N/A ILE 47.A N ILE 43.A O no hydrogen 2.973 N/A ASP 48.A N GLU 44.A O no hydrogen 2.910 N/A ASP 49.A N ALA 45.A O no hydrogen 2.872 N/A VAL 50.A N ILE 46.A O no hydrogen 2.945 N/A VAL 51.A N ILE 47.A O no hydrogen 2.935 N/A LYS 52.A N ASP 48.A O no hydrogen 2.882 N/A GLU 53.A N ASP 49.A O no hydrogen 2.912 N/A TYR 54.A N VAL 50.A O no hydrogen 2.931 N/A GLU 55.A N VAL 51.A O no hydrogen 2.887 N/A ARG 56.A N LYS 52.A O no hydrogen 2.932 N/A ARG 56.A NH1 GLU 53.A OE2 no hydrogen 2.603 N/A ALA 57.A N TYR 54.A O no hydrogen 3.208 N/A GLU 63.A N GLU 60.A O no hydrogen 3.221 N/A VAL 65.A N GLU 63.A O no hydrogen 2.983 N/A VAL 68.A N PRO 64.A O no hydrogen 3.460 N/A ALA 69.A N VAL 65.A O no hydrogen 2.881 N/A ALA 70.A N GLY 66.A O no hydrogen 2.935 N/A GLN 71.A N THR 67.A O no hydrogen 2.918 N/A SER 72.A N VAL 68.A O no hydrogen 2.846 N/A SER 72.A OG VAL 68.A O no hydrogen 2.823 N/A ILE 73.A N ALA 69.A O no hydrogen 2.959 N/A GLY 74.A N ALA 70.A O no hydrogen 2.900 N/A GLU 75.A N GLN 71.A O no hydrogen 2.883 N/A SER 77.A N GLY 74.A O no hydrogen 3.009 N/A SER 77.A OG ILE 73.A O no hydrogen 2.988 N/A THR 78.A N GLU 75.A O no hydrogen 3.330 N/A THR 78.A OG1 GLU 75.A O no hydrogen 2.902 N/A THR 78.A OG1 GLN 79.A OE1 no hydrogen 2.723 N/A GLN 79.A N PRO 76.A O no hydrogen 2.867 N/A THR 81.A N GLN 297.A OE1 no hydrogen 3.267 N/A THR 81.A OG1 GLN 297.A OE1 no hydrogen 3.369 N/A THR 84.A OG1 ASN 83.A O no hydrogen 2.598 N/A HIS 86.A ND1 HIS 86.A O no hydrogen 2.633 N/A ALA 91.A N GLY 89.A O no hydrogen 2.436 N/A THR 96.A N THR 114.A OG1 no hydrogen 3.201 N/A LEU 99.A N THR 81.A O no hydrogen 3.513 N/A ARG 101.A NH1 GLU 104.A OE1 no hydrogen 3.247 N/A ARG 101.A NH2 ASN 268.A O no hydrogen 3.222 N/A ARG 101.A NH2 GLU 289.A OE1 no hydrogen 2.787 N/A ILE 102.A N GLY 98.A O no hydrogen 3.280 N/A ILE 103.A N LEU 99.A O no hydrogen 2.919 N/A GLU 104.A N PRO 100.A O no hydrogen 2.887 N/A ILE 105.A N ARG 101.A O no hydrogen 2.917 N/A VAL 106.A N ILE 102.A O no hydrogen 2.898 N/A ASP 107.A N ILE 103.A O no hydrogen 2.928 N/A ALA 108.A N ILE 105.A O no hydrogen 3.073 N/A ARG 109.A N GLU 104.A O no hydrogen 3.356 N/A ARG 109.A NE GLU 104.A OE2 no hydrogen 3.326 N/A ARG 109.A NH2 GLU 104.A OE2 no hydrogen 3.132 N/A ARG 109.A NH2 SER 113.A OG no hydrogen 3.055 N/A LYS 110.A NZ HIS 271.A ND1 no hydrogen 2.995 N/A SER 113.A N GLU 104.A OE2 no hydrogen 3.048 N/A SER 113.A OG GLU 104.A OE2 no hydrogen 3.122 N/A THR 114.A OG1 THR 114.A O no hydrogen 2.571 N/A MET 116.A N ASN 268.A OD1 no hydrogen 2.806 N/A THR 118.A N ARG 266.A O no hydrogen 3.014 N/A VAL 119.A N ILE 244.A O no hydrogen 2.764 N/A ASP 122.A N GLY 259.A O no hydrogen 2.749 N/A GLU 124.A N ASP 122.A OD2 no hydrogen 2.832 N/A ARG 126.A N GLU 123.A O no hydrogen 3.431 N/A ARG 126.A NE LEU 121.A O no hydrogen 3.061 N/A ARG 126.A NH2 LEU 121.A O no hydrogen 2.640 N/A ARG 129.A NE GLU 133.A OE2 no hydrogen 3.326 N/A ARG 129.A NH2 GLU 133.A OE2 no hydrogen 2.601 N/A LYS 131.A N ASP 128.A OD1 no hydrogen 3.012 N/A ALA 132.A N ASP 128.A O no hydrogen 3.024 N/A GLU 133.A N ARG 129.A O no hydrogen 2.891 N/A GLU 134.A N ALA 130.A O no hydrogen 2.900 N/A VAL 135.A N LYS 131.A O no hydrogen 2.934 N/A ALA 136.A N ALA 132.A O no hydrogen 2.901 N/A ARG 137.A N GLU 133.A O no hydrogen 2.862 N/A ARG 137.A NH1 GLU 133.A O no hydrogen 3.241 N/A ARG 137.A NH1 GLU 133.A OE1 no hydrogen 2.836 N/A ARG 138.A N GLU 134.A O no hydrogen 2.943 N/A ARG 138.A NH2 HIS 125.A NE2 no hydrogen 3.519 N/A ILE 139.A N VAL 135.A O no hydrogen 2.913 N/A GLU 140.A N ALA 136.A O no hydrogen 2.589 N/A THR 142.A N LYS 225.A O no hydrogen 3.426 N/A THR 143.A OG1 GLU 145.A OE1 no hydrogen 2.656 N/A THR 143.A OG1 GLU 145.A OE2 no hydrogen 2.990 N/A GLU 145.A N GLU 145.A OE1 no hydrogen 2.780 N/A ASN 146.A ND2 THR 142.A OG1 no hydrogen 2.506 N/A ALA 148.A N GLU 145.A O no hydrogen 3.258 N/A ARG 149.A NH1 GLU 163.A OE1 no hydrogen 3.342 N/A ARG 149.A NH1 ILE 164.A O no hydrogen 2.459 N/A ARG 149.A NH2 GLU 163.A OE1 no hydrogen 2.694 N/A SER 150.A N GLU 163.A O no hydrogen 2.966 N/A SER 150.A OG ARG 149.A O no hydrogen 2.846 N/A THR 152.A N ILE 161.A O no hydrogen 2.745 N/A PHE 160.A N VAL 201.A O no hydrogen 2.474 N/A ILE 161.A N THR 152.A O no hydrogen 2.855 N/A VAL 162.A N LEU 199.A O no hydrogen 2.635 N/A GLU 163.A N SER 150.A O no hydrogen 2.637 N/A ILE 164.A N TYR 197.A O no hydrogen 3.091 N/A ASP 165.A N LEU 147.A O no hydrogen 3.268 N/A GLU 167.A N ASP 165.A OD1 no hydrogen 2.658 N/A ARG 168.A NH2 ALA 148.A O no hydrogen 2.904 N/A GLU 170.A N PRO 166.A O no hydrogen 2.903 N/A ARG 171.A N GLU 167.A O no hydrogen 2.918 N/A SER 172.A N LEU 169.A O no hydrogen 3.330 N/A SER 172.A OG LEU 169.A O no hydrogen 3.532 N/A THR 175.A OG1 GLU 177.A OE1 no hydrogen 2.680 N/A THR 175.A OG1 GLU 177.A OE2 no hydrogen 3.237 N/A GLU 177.A N GLU 177.A OE1 no hydrogen 2.535 N/A VAL 179.A N THR 175.A O no hydrogen 3.274 N/A VAL 180.A N MET 176.A O no hydrogen 2.896 N/A LYS 181.A N GLU 177.A O no hydrogen 2.856 N/A LYS 182.A N LYS 178.A O no hydrogen 2.971 N/A LEU 183.A N VAL 179.A O no hydrogen 2.886 N/A GLU 184.A N VAL 180.A O no hydrogen 2.898 N/A SER 185.A N LYS 181.A O no hydrogen 2.917 N/A SER 185.A OG LYS 181.A O no hydrogen 3.072 N/A SER 185.A OG LYS 182.A O no hydrogen 2.787 N/A SER 186.A N LYS 182.A O no hydrogen 2.917 N/A SER 186.A OG LYS 182.A O no hydrogen 2.635 N/A SER 186.A OG LEU 183.A O no hydrogen 3.421 N/A PHE 187.A N LEU 183.A O no hydrogen 3.205 N/A GLU 193.A N ILE 200.A O no hydrogen 2.790 N/A ASP 195.A N THR 198.A O no hydrogen 3.041 N/A THR 198.A N ASP 195.A O no hydrogen 3.236 N/A THR 198.A OG1 GLU 163.A OE1 no hydrogen 3.259 N/A THR 198.A OG1 GLU 163.A OE2 no hydrogen 2.854 N/A THR 198.A OG1 GLY 196.A O no hydrogen 3.363 N/A LEU 199.A N VAL 162.A O no hydrogen 2.802 N/A VAL 201.A N PHE 160.A O no hydrogen 2.528 N/A ARG 202.A NE ASN 157.A OD1 no hydrogen 2.861 N/A ASP 207.A N PRO 203.A O no hydrogen 2.896 N/A LYS 208.A N LYS 205.A O no hydrogen 3.307 N/A LYS 208.A NZ SER 210.A OG no hydrogen 3.264 N/A ARG 213.A NE ARG 213.A O no hydrogen 2.910 N/A ALA 216.A N LEU 212.A O no hydrogen 2.715 N/A GLU 217.A N ARG 213.A O no hydrogen 2.925 N/A LYS 218.A N ARG 214.A O no hydrogen 3.376 N/A LYS 218.A NZ ARG 214.A O no hydrogen 3.114 N/A ILE 219.A N PHE 215.A O no hydrogen 2.967 N/A LYS 220.A N ALA 216.A O no hydrogen 2.852 N/A LYS 220.A NZ GLU 217.A OE1 no hydrogen 3.312 N/A LYS 221.A N GLU 217.A O no hydrogen 2.904 N/A LYS 221.A NZ GLU 145.A OE2 no hydrogen 2.644 N/A HIS 222.A N ILE 219.A O no hydrogen 3.319 N/A ARG 223.A NH1 GLY 226.A O no hydrogen 3.373 N/A LYS 225.A NZ ARG 137.A O no hydrogen 2.535 N/A LYS 225.A NZ GLU 140.A O no hydrogen 3.272 N/A LEU 227.A N ILE 139.A O no hydrogen 3.250 N/A THR 233.A OG1 TYR 245.A O no hydrogen 3.458 N/A ILE 234.A N TYR 245.A O no hydrogen 2.824 N/A ARG 236.A N VAL 243.A O no hydrogen 3.249 N/A ARG 236.A NE GLU 238.A OE2 no hydrogen 2.498 N/A ARG 236.A NH1 ALA 91.A O no hydrogen 2.821 N/A ARG 236.A NH2 GLU 238.A OE2 no hydrogen 2.728 N/A GLU 238.A N GLU 241.A O no hydrogen 2.862 N/A GLU 241.A N GLU 238.A O no hydrogen 2.896 N/A TYR 242.A N ARG 126.A O no hydrogen 3.133 N/A VAL 243.A N ARG 236.A O no hydrogen 2.975 N/A ILE 244.A N VAL 119.A O no hydrogen 2.971 N/A TYR 245.A N ILE 234.A O no hydrogen 2.898 N/A TYR 245.A OH GLU 238.A OE2 no hydrogen 2.549 N/A THR 246.A N MET 117.A O no hydrogen 3.253 N/A THR 246.A OG1 MET 117.A O no hydrogen 3.418 N/A GLU 247.A N LYS 232.A O no hydrogen 3.005 N/A GLY 248.A N GLU 247.A OE1 no hydrogen 3.204 N/A SER 249.A OG GLU 272.A OE1 no hydrogen 2.894 N/A ASN 250.A ND2 SER 228.A O no hydrogen 3.305 N/A PHE 251.A N GLU 272.A OE2 no hydrogen 2.907 N/A LYS 256.A N GLN 253.A O no hydrogen 3.102 N/A VAL 257.A N VAL 254.A O no hydrogen 3.009 N/A VAL 260.A N VAL 257.A O no hydrogen 3.421 N/A ASP 261.A N TYR 120.A O no hydrogen 2.599 N/A THR 263.A N ASP 261.A OD1 no hydrogen 3.344 N/A THR 263.A OG1 ASP 261.A OD1 no hydrogen 2.931 N/A ARG 264.A N ASP 261.A O no hydrogen 3.395 N/A ARG 264.A NE ASP 261.A OD2 no hydrogen 3.518 N/A ARG 264.A NH1 GLU 241.A OE1 no hydrogen 3.125 N/A ARG 264.A NH2 GLU 241.A OE2 no hydrogen 3.112 N/A ARG 264.A NH2 ASP 261.A OD2 no hydrogen 3.307 N/A THR 265.A OG1 ASP 261.A O no hydrogen 3.126 N/A ARG 266.A N THR 118.A O no hydrogen 3.097 N/A THR 267.A OG1 MET 116.A O no hydrogen 3.475 N/A ASN 268.A N MET 116.A O no hydrogen 2.917 N/A ASN 268.A ND2 THR 114.A O no hydrogen 2.950 N/A ASN 269.A N THR 267.A OG1 no hydrogen 3.309 N/A HIS 271.A N ASN 269.A OD1 no hydrogen 3.151 N/A HIS 271.A NE2 ALA 108.A O no hydrogen 2.996 N/A GLU 272.A N ASN 269.A O no hydrogen 3.347 N/A ILE 273.A N ASN 269.A O no hydrogen 3.405 N/A ALA 274.A N ILE 270.A O no hydrogen 2.928 N/A VAL 276.A N GLU 272.A O no hydrogen 2.916 N/A LEU 277.A N ILE 273.A O no hydrogen 2.768 N/A GLY 278.A N ALA 274.A O no hydrogen 3.155 N/A ALA 282.A N GLY 278.A O no hydrogen 3.405 N/A ARG 283.A N ILE 279.A O no hydrogen 2.920 N/A ARG 283.A NE ASP 311.A OD1 no hydrogen 2.937 N/A ARG 283.A NH2 ASP 311.A OD2 no hydrogen 2.980 N/A ASN 284.A N GLU 280.A O no hydrogen 2.954 N/A ALA 285.A N ALA 281.A O no hydrogen 2.873 N/A ILE 286.A N ALA 282.A O no hydrogen 2.884 N/A ILE 287.A N ARG 283.A O no hydrogen 2.991 N/A ASP 288.A N ASN 284.A O no hydrogen 2.939 N/A GLU 289.A N ALA 285.A O no hydrogen 2.856 N/A ILE 290.A N ILE 286.A O no hydrogen 2.980 N/A VAL 291.A N ILE 287.A O no hydrogen 2.948 N/A SER 292.A N ASP 288.A O no hydrogen 2.908 N/A SER 292.A OG GLU 289.A O no hydrogen 3.253 N/A THR 293.A N GLU 289.A O no hydrogen 2.913 N/A THR 293.A OG1 GLU 289.A O no hydrogen 2.843 N/A MET 294.A N ILE 290.A O no hydrogen 2.965 N/A GLN 295.A N VAL 291.A O no hydrogen 2.870 N/A GLU 296.A N SER 292.A O no hydrogen 2.925 N/A GLY 298.A N GLN 295.A O no hydrogen 3.009 N/A ARG 304.A NE ASP 302.A OD2 no hydrogen 2.858 N/A ARG 304.A NH2 ASP 302.A OD2 no hydrogen 3.072 N/A MET 307.A N ILE 303.A O no hydrogen 2.908 N/A LEU 308.A N ARG 304.A O no hydrogen 2.937 N/A VAL 309.A N HIS 305.A O no hydrogen 2.967 N/A ALA 310.A N ILE 306.A O no hydrogen 2.904 N/A ASP 311.A N MET 307.A O no hydrogen 2.881 N/A MET 312.A N LEU 308.A O no hydrogen 2.934 N/A MET 313.A N VAL 309.A O no hydrogen 2.955 N/A THR 314.A N ALA 310.A O no hydrogen 2.915 N/A THR 314.A OG1 ALA 310.A O no hydrogen 2.664 N/A ARG 320.A NH1 ASP 316.A OD2 no hydrogen 3.005 N/A ILE 322.A N VAL 106.A O no hydrogen 3.356 N/A ARG 324.A NH1 GLU 341.A OE1 no hydrogen 2.400 N/A GLY 326.A N GLY 323.A O no hydrogen 3.275 N/A VAL 327.A N PRO 321.A O no hydrogen 3.024 N/A GLU 330.A N GLY 326.A O no hydrogen 2.975 N/A GLU 330.A N VAL 327.A O no hydrogen 3.112 N/A LYS 331.A N VAL 328.A O no hydrogen 3.345 N/A SER 333.A OG ASP 357.A OD1 no hydrogen 3.419 N/A SER 333.A OG ASP 357.A OD2 no hydrogen 2.626 N/A LEU 335.A N ASP 357.A OD2 no hydrogen 3.161 N/A ALA 336.A N SER 333.A OG no hydrogen 2.997 N/A ARG 337.A N SER 333.A O no hydrogen 3.502 N/A ARG 337.A NH1 LYS 331.A O no hydrogen 2.595 N/A ARG 337.A NH1 SER 332.A O no hydrogen 3.256 N/A ARG 337.A NH1 GLU 355.A OE2 no hydrogen 3.131 N/A ARG 337.A NH2 GLU 355.A OE2 no hydrogen 3.257 N/A ALA 338.A N VAL 334.A O no hydrogen 2.893 N/A ALA 339.A N LEU 335.A O no hydrogen 3.033 N/A PHE 340.A N ARG 337.A O no hydrogen 3.161 N/A GLN 345.A N GLN 345.A OE1 no hydrogen 2.846 N/A HIS 346.A N ILE 342.A O no hydrogen 3.411 N/A LEU 347.A N THR 343.A O no hydrogen 2.927 N/A PHE 348.A N VAL 344.A O no hydrogen 2.934 N/A GLU 349.A N GLN 345.A O no hydrogen 2.912 N/A ALA 350.A N HIS 346.A O no hydrogen 2.906 N/A ALA 351.A N LEU 347.A O no hydrogen 2.930 N/A GLU 352.A N PHE 348.A O no hydrogen 2.920 N/A LYS 353.A N GLU 349.A O no hydrogen 2.925 N/A GLU 355.A N ALA 350.A O no hydrogen 3.133 N/A LEU 359.A N ASP 357.A OD1 no hydrogen 3.063 N/A GLY 361.A N GLU 364.A OE2 no hydrogen 2.844 N/A GLU 364.A N GLU 364.A OE1 no hydrogen 2.638 N/A ASN 365.A ND2 LEU 359.A O no hydrogen 3.302 N/A ASN 365.A ND2 GLY 361.A O no hydrogen 2.302 N/A VAL 366.A N VAL 362.A O no hydrogen 2.916 N/A LEU 367.A N ILE 363.A O no hydrogen 2.912 N/A ILE 368.A N GLU 364.A O no hydrogen 2.908 N/A GLY 369.A N ASN 365.A O no hydrogen 2.793 N/A GLN 370.A N ASN 365.A O no hydrogen 3.231 N/A GLN 370.A NE2 ASN 365.A OD1 no hydrogen 3.225 N/A GLY 375.A N GLY 62.A O no hydrogen 2.956 N/A GLY 377.A N VAL 374.A O no hydrogen 2.858 N/A MET 378.A N GLY 375.A O no hydrogen 3.481 N/A LEU 387.A N LEU 385.A O no hydrogen 2.416 N/A