Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8p4e_M.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): THR 14.A N HIS 93.A O no hydrogen 3.057 N/A VAL 16.A N VAL 91.A O no hydrogen 2.792 N/A LYS 21.A NZ GLU 24.A OE2 no hydrogen 2.906 N/A LYS 21.A NZ GLU 81.A OE2 no hydrogen 3.314 N/A LEU 22.A N THR 18.A O no hydrogen 3.100 N/A GLY 23.A N GLN 19.A O no hydrogen 3.435 N/A VAL 25.A N LYS 21.A O no hydrogen 2.967 N/A GLN 26.A N LEU 22.A O no hydrogen 3.044 N/A GLN 26.A NE2 ASN 89.A O no hydrogen 2.797 N/A GLN 27.A N GLY 23.A O no hydrogen 3.079 N/A LYS 28.A N GLU 24.A O no hydrogen 2.947 N/A LYS 28.A NZ ASP 77.A OD1 no hydrogen 3.130 N/A LYS 28.A NZ ASP 77.A OD2 no hydrogen 3.058 N/A LYS 28.A NZ ASN 111.A OD1 no hydrogen 2.637 N/A CYS 29.A N GLN 26.A O no hydrogen 2.962 N/A CYS 29.A SG VAL 25.A O no hydrogen 3.561 N/A HIS 30.A N GLN 26.A O no hydrogen 3.232 N/A HIS 30.A ND1 GLN 26.A O no hydrogen 3.192 N/A GLN 31.A N GLN 27.A O no hydrogen 3.017 N/A PHE 32.A N LYS 28.A O no hydrogen 2.977 N/A CYS 33.A N CYS 29.A O no hydrogen 2.957 N/A CYS 33.A N HIS 30.A O no hydrogen 3.237 N/A CYS 33.A SG CYS 29.A O no hydrogen 3.624 N/A GLY 34.A N GLN 31.A O no hydrogen 3.072 N/A TRP 35.A N HIS 30.A O no hydrogen 3.064 N/A ALA 43.A N TYR 210.A OH no hydrogen 2.893 N/A GLN 44.A N GLY 213.A O no hydrogen 2.588 N/A VAL 46.A N ILE 218.A O no hydrogen 2.891 N/A MET 48.A N LYS 220.A O no hydrogen 3.283 N/A LYS 50.A NZ ASN 313.A OD1 no hydrogen 3.117 N/A ASN 52.A N ASP 49.A OD2 no hydrogen 2.556 N/A ILE 53.A N ASP 49.A O no hydrogen 3.385 N/A LEU 55.A N ASN 52.A O no hydrogen 2.729 N/A LEU 56.A N ILE 53.A O no hydrogen 3.355 N/A ASP 57.A N LYS 54.A O no hydrogen 3.135 N/A LEU 58.A N LEU 55.A O no hydrogen 2.988 N/A LYS 59.A NZ ASP 217.A OD2 no hydrogen 3.209 N/A TYR 61.A OH ASP 217.A O no hydrogen 2.459 N/A LYS 62.A N GLN 205.A O no hydrogen 2.771 N/A LYS 62.A NZ ASP 189.A OD1 no hydrogen 2.734 N/A VAL 63.A N PHE 188.A O no hydrogen 2.761 N/A SER 64.A N ILE 203.A O no hydrogen 3.128 N/A SER 64.A OG PRO 186.A O no hydrogen 2.560 N/A THR 70.A N MET 118.A O no hydrogen 2.884 N/A ARG 71.A NE ASP 115.A OD2 no hydrogen 2.934 N/A ARG 71.A NH1 ALA 43.A O no hydrogen 2.976 N/A ARG 71.A NH2 ALA 43.A O no hydrogen 2.790 N/A TYR 72.A N GLY 116.A O no hydrogen 2.965 N/A TYR 72.A OH PHE 4.A O no hydrogen 2.504 N/A TYR 72.A OH ASP 86.A OD1 no hydrogen 3.211 N/A MET 73.A N ILE 85.A O no hydrogen 3.040 N/A MET 74.A N LEU 114.A O no hydrogen 2.943 N/A LEU 75.A N PHE 83.A O no hydrogen 2.866 N/A ILE 76.A N THR 112.A O no hydrogen 2.944 N/A THR 79.A OG1 HIS 108.A ND1 no hydrogen 3.175 N/A PHE 83.A N LEU 75.A O no hydrogen 2.922 N/A MET 84.A N PHE 92.A O no hydrogen 2.910 N/A ILE 85.A N MET 73.A O no hydrogen 2.753 N/A ASP 86.A N SER 90.A O no hydrogen 2.978 N/A ASN 89.A N ASP 86.A O no hydrogen 3.016 N/A SER 90.A OG ASP 86.A OD2 no hydrogen 3.393 N/A PHE 92.A N MET 84.A O no hydrogen 2.959 N/A HIS 93.A N THR 14.A O no hydrogen 2.865 N/A HIS 93.A NE2 ASN 80.A O no hydrogen 2.529 N/A VAL 94.A N VAL 82.A O no hydrogen 2.971 N/A SER 95.A OG GLY 12.A O no hydrogen 3.296 N/A GLU 98.A N GLU 178.A OE2 no hydrogen 3.238 N/A PHE 101.A N MET 107.A O no hydrogen 3.264 N/A ARG 102.A NE GLU 159.A OE1 no hydrogen 3.350 N/A ARG 106.A N ASP 104.A OD1 no hydrogen 3.220 N/A MET 107.A N ASP 104.A O no hydrogen 2.854 N/A LEU 109.A N PHE 99.A O no hydrogen 3.024 N/A SER 110.A OG ASP 77.A O no hydrogen 3.040 N/A SER 110.A OG ASP 77.A OD2 no hydrogen 3.487 N/A ASN 111.A N ASP 77.A OD2 no hydrogen 3.202 N/A THR 112.A N ILE 76.A O no hydrogen 3.166 N/A THR 112.A OG1 SER 110.A O no hydrogen 3.355 N/A LEU 113.A N LYS 138.A O no hydrogen 3.159 N/A LEU 114.A N MET 74.A O no hydrogen 2.852 N/A ASP 115.A N ASP 135.A O no hydrogen 2.771 N/A GLY 116.A N TYR 72.A O no hydrogen 3.216 N/A GLU 117.A N LEU 132.A O no hydrogen 2.990 N/A MET 118.A N THR 70.A O no hydrogen 2.741 N/A ILE 119.A N ARG 130.A O no hydrogen 2.854 N/A ASP 121.A N VAL 128.A O no hydrogen 3.134 N/A ASN 124.A N ASN 124.A OD1 no hydrogen 2.609 N/A GLN 126.A N ASN 124.A OD1 no hydrogen 3.234 N/A VAL 128.A N ASP 121.A O no hydrogen 3.236 N/A ARG 130.A N ILE 119.A O no hydrogen 2.884 N/A TYR 131.A N SER 181.A O no hydrogen 2.957 N/A TYR 131.A OH TYR 72.A O no hydrogen 2.632 N/A LEU 132.A N GLU 117.A O no hydrogen 2.857 N/A ILE 133.A N ARG 183.A O no hydrogen 2.503 N/A TYR 134.A N ASP 115.A O no hydrogen 2.775 N/A ASP 135.A N ASP 115.A O no hydrogen 3.126 N/A ILE 137.A N LEU 113.A O no hydrogen 2.788 N/A LYS 138.A N LEU 113.A O no hydrogen 3.496 N/A LYS 138.A NZ PHE 32.A O no hydrogen 3.280 N/A PHE 139.A N GLN 142.A O no hydrogen 2.849 N/A SER 141.A N ASN 111.A O no hydrogen 3.077 N/A GLY 145.A N ILE 137.A O no hydrogen 2.930 N/A ASP 146.A N PRO 143.A O no hydrogen 2.957 N/A CYS 147.A N VAL 144.A O no hydrogen 3.162 N/A PHE 149.A N THR 207.A O no hydrogen 2.964 N/A ASN 150.A ND2 ASP 148.A OD2 no hydrogen 3.085 N/A ARG 152.A N ASP 148.A O no hydrogen 2.900 N/A ARG 152.A NH1 GLY 145.A O no hydrogen 3.138 N/A ARG 152.A NH1 GLY 208.A O no hydrogen 3.262 N/A LEU 153.A N PHE 149.A O no hydrogen 3.006 N/A GLN 154.A N ASN 150.A O no hydrogen 2.766 N/A CYS 155.A N VAL 151.A O no hydrogen 2.764 N/A ILE 156.A N ARG 152.A O no hydrogen 3.162 N/A ARG 158.A N GLN 154.A O no hydrogen 3.122 N/A ARG 158.A NH1 GLU 159.A OE2 no hydrogen 2.938 N/A GLU 159.A N CYS 155.A O no hydrogen 2.676 N/A ILE 160.A N ILE 156.A O no hydrogen 3.277 N/A ILE 161.A N GLU 157.A O no hydrogen 3.277 N/A SER 162.A N GLU 157.A O no hydrogen 3.016 N/A ARG 164.A NE GLU 98.A O no hydrogen 3.285 N/A ARG 164.A NH2 GLU 178.A OE2 no hydrogen 2.800 N/A HIS 165.A N ILE 161.A O no hydrogen 2.839 N/A GLU 166.A N SER 162.A O no hydrogen 2.785 N/A LYS 167.A N PRO 163.A O no hydrogen 3.136 N/A LYS 167.A NZ GLU 98.A OE2 no hydrogen 3.155 N/A MET 168.A N HIS 165.A O no hydrogen 2.854 N/A LYS 169.A N HIS 165.A O no hydrogen 2.925 N/A THR 170.A N GLU 166.A O no hydrogen 3.316 N/A THR 170.A OG1 LYS 167.A O no hydrogen 3.154 N/A LEU 172.A N THR 170.A OG1 no hydrogen 3.321 N/A ILE 173.A N LYS 167.A O no hydrogen 2.893 N/A LYS 175.A NZ SER 181.A OG no hydrogen 3.331 N/A THR 176.A N ASP 174.A OD2 no hydrogen 3.085 N/A GLN 177.A N ASP 174.A O no hydrogen 2.888 N/A GLU 178.A N LYS 175.A O no hydrogen 3.194 N/A SER 181.A N PRO 129.A O no hydrogen 3.234 N/A ARG 183.A N TYR 131.A O no hydrogen 2.812 N/A LYS 185.A N ILE 133.A O no hydrogen 3.240 N/A PHE 188.A N VAL 63.A O no hydrogen 2.795 N/A THR 192.A N ASP 189.A O no hydrogen 3.429 N/A SER 193.A OG ILE 190.A O no hydrogen 2.875 N/A LEU 202.A N TRP 221.A O no hydrogen 2.733 N/A ILE 203.A N SER 64.A O no hydrogen 2.790 N/A PHE 204.A N LEU 219.A O no hydrogen 2.672 N/A GLN 205.A N LYS 62.A O no hydrogen 2.788 N/A TYR 210.A N GLY 145.A O no hydrogen 2.781 N/A TYR 210.A OH ASP 115.A OD1 no hydrogen 2.708 N/A LYS 211.A NZ ARG 214.A O no hydrogen 3.290 N/A CYS 215.A N GLN 44.A O no hydrogen 2.792 N/A CYS 215.A SG LYS 211.A O no hydrogen 3.652 N/A CYS 215.A SG GLY 213.A O no hydrogen 3.702 N/A ILE 218.A N CYS 215.A O no hydrogen 3.340 N/A LEU 219.A N PHE 204.A O no hydrogen 2.993 N/A LYS 220.A N VAL 46.A O no hydrogen 2.930 N/A TRP 221.A N LEU 202.A O no hydrogen 2.838 N/A TRP 221.A NE1 VAL 315.A O no hydrogen 3.102 N/A LEU 226.A N PRO 223.A O no hydrogen 2.991 N/A ASN 227.A N PRO 224.A O no hydrogen 3.438 N/A SER 228.A OG LEU 226.A O no hydrogen 3.351 N/A VAL 229.A N CYS 279.A O no hydrogen 3.102 N/A ASP 230.A N ASN 299.A OD1 no hydrogen 2.681 N/A PHE 231.A N ILE 277.A O no hydrogen 3.037 N/A ARG 232.A N TYR 252.A O no hydrogen 2.882 N/A LYS 234.A N LEU 250.A O no hydrogen 2.736 N/A THR 236.A N VAL 248.A O no hydrogen 3.252 N/A ARG 237.A NE PRO 245.A O no hydrogen 2.554 N/A ARG 237.A NH2 PRO 245.A O no hydrogen 2.773 N/A MET 238.A N GLN 246.A O no hydrogen 2.813 N/A GLU 241.A N GLU 241.A OE1 no hydrogen 2.910 N/A ASN 247.A N ASN 247.A OD1 no hydrogen 2.264 N/A VAL 248.A N THR 236.A O no hydrogen 2.827 N/A LEU 250.A N LYS 234.A O no hydrogen 2.671 N/A LEU 251.A N ALA 261.A O no hydrogen 3.125 N/A TYR 252.A N ARG 232.A O no hydrogen 2.908 N/A GLY 254.A N ASN 299.A O no hydrogen 2.684 N/A PHE 260.A N LEU 251.A O no hydrogen 3.167 N/A ILE 263.A N GLY 249.A O no hydrogen 2.925 N/A LEU 269.A N THR 266.A O no hydrogen 3.233 N/A LEU 269.A N THR 266.A OG1 no hydrogen 2.938 N/A GLN 271.A NE2 LYS 267.A O no hydrogen 3.166 N/A TYR 272.A N LEU 269.A O no hydrogen 3.210 N/A TYR 272.A OH GLU 268.A OE2 no hydrogen 3.073 N/A ASP 273.A N LYS 270.A O no hydrogen 3.138 N/A LYS 275.A N TYR 272.A O no hydrogen 2.845 N/A ILE 277.A N PHE 231.A O no hydrogen 2.820 N/A GLU 278.A N ARG 290.A O no hydrogen 3.410 N/A CYS 279.A N VAL 229.A O no hydrogen 3.081 N/A LYS 280.A N VAL 287.A O no hydrogen 3.043 N/A LYS 280.A NZ GLU 282.A OE2 no hydrogen 3.143 N/A ASN 283.A N SER 285.A OG no hydrogen 3.137 N/A VAL 287.A N LYS 280.A O no hydrogen 3.149 N/A MET 289.A N GLU 278.A O no hydrogen 3.146 N/A ASN 299.A N ASP 230.A O no hydrogen 3.266 N/A TYR 301.A N GLY 254.A O no hydrogen 2.392 N/A THR 303.A N ALA 300.A O no hydrogen 2.765 N/A ALA 304.A N ALA 300.A O no hydrogen 3.019 N/A MET 305.A N TYR 301.A O no hydrogen 2.983 N/A ALA 306.A N ASN 302.A O no hydrogen 3.200 N/A VAL 307.A N ALA 304.A O no hydrogen 2.973 N/A CYS 308.A N ALA 304.A O no hydrogen 2.950 N/A CYS 308.A SG ALA 304.A O no hydrogen 3.768 N/A ASN 309.A N MET 305.A O no hydrogen 2.725 N/A SER 310.A N VAL 307.A O no hydrogen 2.995 N/A SER 310.A OG ALA 306.A O no hydrogen 3.418 N/A ILE 311.A N VAL 307.A O no hydrogen 2.982 N/A SER 312.A N CYS 308.A O no hydrogen 2.985 N/A SER 312.A OG CYS 308.A O no hydrogen 3.238 N/A LYS 317.A NZ SER 225.A OG no hydrogen 2.500 N/A MET 319.A N THR 316.A OG1 no hydrogen 2.944 N/A LEU 320.A N THR 316.A O no hydrogen 3.000 N/A GLU 322.A N GLU 318.A O no hydrogen 3.095 N/A PHE 323.A N MET 319.A O no hydrogen 3.135 N/A ILE 324.A N LEU 320.A O no hydrogen 3.011 N/A ASP 325.A N PHE 321.A O no hydrogen 3.027 N/A ARG 326.A N GLU 322.A O no hydrogen 3.059 N/A ARG 326.A NH1 ASP 57.A OD2 no hydrogen 2.601 N/A CYS 327.A N PHE 323.A O no hydrogen 3.504 N/A THR 328.A N ILE 324.A O no hydrogen 2.919 N/A THR 328.A OG1 ILE 324.A O no hydrogen 2.994 N/A ALA 329.A N ARG 326.A O no hydrogen 2.940 N/A