Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8p70_I.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): TYR 2.A OH THR 12.A OG1 no hydrogen 3.236 N/A SER 5.A N TYR 2.A O no hydrogen 3.016 N/A SER 5.A OG TYR 2.A O no hydrogen 2.793 N/A GLN 7.A NE2 HIS 156.A O no hydrogen 3.136 N/A LYS 8.A N SER 5.A OG no hydrogen 3.184 N/A LYS 8.A NZ HIS 3.A O no hydrogen 2.780 N/A ARG 9.A N SER 5.A O no hydrogen 3.268 N/A ARG 9.A NH1 HIS 10.A NE2 no hydrogen 3.361 N/A HIS 10.A N SER 6.A O no hydrogen 2.880 N/A TRP 11.A N GLN 7.A O no hydrogen 3.029 N/A TRP 11.A NE1 HIS 152.A ND1 no hydrogen 2.925 N/A THR 12.A OG1 TYR 2.A OH no hydrogen 3.236 N/A THR 12.A OG1 GLN 7.A O no hydrogen 2.636 N/A THR 12.A OG1 LYS 8.A O no hydrogen 3.476 N/A PHE 13.A N LEU 200.A O no hydrogen 2.510 N/A GLN 18.A N SER 15.A O no hydrogen 3.221 N/A ALA 20.A N GLU 16.A O no hydrogen 2.928 N/A ARG 21.A N GLU 17.A O no hydrogen 2.872 N/A LEU 22.A N GLN 18.A O no hydrogen 2.925 N/A ARG 23.A N LEU 19.A O no hydrogen 2.967 N/A ARG 23.A NH1 ASP 197.A OD2 no hydrogen 2.906 N/A ARG 23.A NH2 ASP 197.A OD1 no hydrogen 2.429 N/A ARG 23.A NH2 ASP 197.A OD2 no hydrogen 3.198 N/A ALA 24.A N ALA 20.A O no hydrogen 2.864 N/A ASP 25.A N ARG 21.A O no hydrogen 2.881 N/A ALA 26.A N LEU 22.A O no hydrogen 2.965 N/A ASN 27.A N ARG 23.A O no hydrogen 2.948 N/A ASN 27.A ND2 LEU 43.A O no hydrogen 2.532 N/A ASN 27.A ND2 GLU 48.A OE2 no hydrogen 2.718 N/A ARG 28.A N ALA 24.A O no hydrogen 2.894 N/A ARG 28.A NE ASP 25.A OD1 no hydrogen 3.432 N/A ARG 28.A NH2 ASP 25.A OD1 no hydrogen 2.956 N/A LYS 29.A N ASP 25.A O no hydrogen 2.865 N/A PHE 30.A N ALA 26.A O no hydrogen 2.975 N/A ARG 31.A N ASN 27.A O no hydrogen 2.959 N/A ARG 31.A NE ASN 27.A OD1 no hydrogen 2.730 N/A ARG 31.A NH2 LEU 43.A O no hydrogen 2.924 N/A CYS 32.A N ARG 28.A O no hydrogen 2.909 N/A CYS 32.A SG ARG 28.A O no hydrogen 3.224 N/A LYS 33.A N LYS 29.A O no hydrogen 2.936 N/A ALA 34.A N PHE 30.A O no hydrogen 2.887 N/A VAL 35.A N ARG 31.A O no hydrogen 2.917 N/A ALA 36.A N CYS 32.A O no hydrogen 2.940 N/A ASN 37.A N LYS 33.A O no hydrogen 2.889 N/A GLY 38.A N ALA 34.A O no hydrogen 2.831 N/A PHE 42.A N ASP 39.A O no hydrogen 3.276 N/A GLU 44.A N GLU 47.A OE1 no hydrogen 2.403 N/A GLU 48.A N GLU 44.A O no hydrogen 3.003 N/A MET 49.A N PRO 45.A O no hydrogen 2.885 N/A THR 50.A N HIS 46.A O no hydrogen 2.941 N/A THR 50.A OG1 HIS 46.A O no hydrogen 2.848 N/A LEU 51.A N GLU 47.A O no hydrogen 2.979 N/A CYS 52.A N GLU 48.A O no hydrogen 2.844 N/A CYS 52.A SG GLU 48.A O no hydrogen 3.365 N/A LYS 53.A N MET 49.A O no hydrogen 2.891 N/A LYS 53.A NZ GLU 258.A O no hydrogen 2.791 N/A TYR 54.A N THR 50.A O no hydrogen 2.968 N/A TYR 55.A N LEU 51.A O no hydrogen 2.921 N/A GLU 56.A N CYS 52.A O no hydrogen 2.833 N/A LYS 57.A N LYS 53.A O no hydrogen 2.993 N/A ARG 58.A N TYR 54.A O no hydrogen 2.934 N/A LEU 59.A N TYR 55.A O no hydrogen 2.841 N/A LEU 60.A N GLU 56.A O no hydrogen 2.943 N/A GLU 61.A N LYS 57.A O no hydrogen 2.944 N/A PHE 62.A N ARG 58.A O no hydrogen 2.869 N/A CYS 63.A N LEU 59.A O no hydrogen 2.916 N/A CYS 63.A SG LEU 59.A O no hydrogen 3.167 N/A SER 64.A N LEU 60.A O no hydrogen 2.927 N/A SER 64.A N GLU 61.A O no hydrogen 3.270 N/A SER 64.A OG GLU 61.A O no hydrogen 3.054 N/A VAL 65.A N PHE 62.A O no hydrogen 3.447 N/A LYS 67.A N ASN 123.A OD1 no hydrogen 2.626 N/A SER 73.A OG ASP 111.A OD2 no hydrogen 2.489 N/A VAL 75.A N PRO 71.A O no hydrogen 3.180 N/A GLY 76.A N ARG 72.A O no hydrogen 2.925 N/A THR 77.A N SER 73.A O no hydrogen 2.928 N/A THR 77.A OG1 SER 73.A O no hydrogen 2.816 N/A ALA 78.A N VAL 74.A O no hydrogen 2.900 N/A CYS 79.A N VAL 75.A O no hydrogen 2.915 N/A CYS 79.A SG VAL 75.A O no hydrogen 3.396 N/A MET 80.A N GLY 76.A O no hydrogen 2.927 N/A TYR 81.A N THR 77.A O no hydrogen 2.906 N/A TYR 81.A OH LEU 153.A O no hydrogen 2.395 N/A PHE 82.A N ALA 78.A O no hydrogen 2.934 N/A LYS 83.A N CYS 79.A O no hydrogen 2.979 N/A LYS 83.A NZ GLU 56.A OE1 no hydrogen 2.823 N/A LYS 83.A NZ ALA 194.A O no hydrogen 3.094 N/A LYS 83.A NZ THR 196.A O no hydrogen 2.934 N/A ARG 84.A N MET 80.A O no hydrogen 2.914 N/A PHE 85.A N TYR 81.A O no hydrogen 2.865 N/A TYR 86.A N PHE 82.A O no hydrogen 3.041 N/A TYR 86.A OH TYR 94.A O no hydrogen 2.635 N/A LEU 87.A N LYS 83.A O no hydrogen 2.954 N/A LEU 87.A N ARG 84.A O no hydrogen 3.324 N/A ASN 88.A N PHE 85.A O no hydrogen 3.409 N/A ASN 89.A ND2 PHE 85.A O no hydrogen 2.799 N/A ASN 89.A ND2 GLN 148.A OE1 no hydrogen 2.696 N/A SER 90.A OG GLU 48.A OE2 no hydrogen 2.517 N/A VAL 91.A N GLU 48.A OE1 no hydrogen 3.311 N/A MET 92.A N SER 90.A OG no hydrogen 2.970 N/A GLU 93.A N SER 90.A O no hydrogen 3.160 N/A TYR 94.A N SER 90.A O no hydrogen 3.282 N/A ARG 97.A N HIS 95.A ND1 no hydrogen 3.059 N/A ILE 98.A N HIS 95.A O no hydrogen 3.195 N/A ILE 99.A N HIS 95.A O no hydrogen 3.068 N/A MET 100.A N PRO 96.A O no hydrogen 2.900 N/A THR 102.A N ILE 98.A O no hydrogen 2.916 N/A THR 102.A OG1 ILE 98.A O no hydrogen 2.824 N/A CYS 103.A N ILE 99.A O no hydrogen 2.833 N/A CYS 103.A SG ILE 99.A O no hydrogen 3.119 N/A ALA 104.A N MET 100.A O no hydrogen 2.956 N/A PHE 105.A N LEU 101.A O no hydrogen 2.913 N/A LEU 106.A N THR 102.A O no hydrogen 2.894 N/A ALA 107.A N CYS 103.A O no hydrogen 2.872 N/A CYS 108.A N ALA 104.A O no hydrogen 2.904 N/A CYS 108.A SG ALA 104.A O no hydrogen 3.256 N/A LYS 109.A N PHE 105.A O no hydrogen 3.047 N/A LYS 109.A NZ GLU 142.A OE1 no hydrogen 3.179 N/A LYS 109.A NZ GLU 142.A OE2 no hydrogen 2.766 N/A VAL 110.A N LEU 106.A O no hydrogen 2.846 N/A ASP 111.A N ALA 107.A O no hydrogen 2.885 N/A GLU 112.A N LYS 109.A O no hydrogen 3.251 N/A PHE 113.A N CYS 108.A O no hydrogen 2.993 N/A PHE 120.A N SER 116.A O no hydrogen 2.756 N/A VAL 121.A N SER 117.A O no hydrogen 2.923 N/A GLY 122.A N PRO 118.A O no hydrogen 2.890 N/A ASN 123.A N PHE 120.A O no hydrogen 3.197 N/A ASN 123.A ND2 LYS 67.A O no hydrogen 2.933 N/A ASN 123.A ND2 PHE 120.A O no hydrogen 3.482 N/A LEU 124.A N VAL 121.A O no hydrogen 3.159 N/A GLN 131.A N SER 127.A O no hydrogen 2.817 N/A GLN 131.A NE2 LEU 124.A O no hydrogen 3.085 N/A GLU 132.A N PRO 128.A O no hydrogen 2.906 N/A LYS 133.A N LEU 129.A O no hydrogen 2.919 N/A ALA 134.A N GLY 130.A O no hydrogen 2.877 N/A LEU 135.A N GLN 131.A O no hydrogen 2.887 N/A GLU 136.A N GLU 132.A O no hydrogen 2.945 N/A GLN 137.A N LYS 133.A O no hydrogen 2.930 N/A ILE 138.A N ALA 134.A O no hydrogen 2.870 N/A LEU 139.A N LEU 135.A O no hydrogen 2.893 N/A GLU 140.A N GLU 136.A O no hydrogen 2.947 N/A TYR 141.A N GLN 137.A O no hydrogen 2.921 N/A LEU 145.A N TYR 141.A O no hydrogen 2.872 N/A ILE 146.A N GLU 142.A O no hydrogen 2.953 N/A GLN 147.A N LEU 143.A O no hydrogen 2.884 N/A GLN 148.A N LEU 144.A O no hydrogen 2.903 N/A LEU 149.A N LEU 145.A O no hydrogen 3.026 N/A LEU 149.A N ILE 146.A O no hydrogen 3.223 N/A ASN 150.A N GLN 147.A O no hydrogen 2.912 N/A PHE 151.A N ILE 146.A O no hydrogen 3.096 N/A HIS 152.A N LEU 149.A O no hydrogen 3.067 N/A HIS 156.A N GLN 7.A OE1 no hydrogen 2.833 N/A ASN 157.A ND2 SER 73.A O no hydrogen 3.234 N/A PHE 162.A N PRO 158.A O no hydrogen 2.899 N/A GLU 163.A N TYR 159.A O no hydrogen 2.944 N/A GLY 164.A N ARG 160.A O no hydrogen 2.903 N/A PHE 165.A N PRO 161.A O no hydrogen 2.873 N/A LEU 166.A N PHE 162.A O no hydrogen 2.966 N/A ILE 167.A N GLU 163.A O no hydrogen 2.957 N/A ASP 168.A N GLY 164.A O no hydrogen 2.929 N/A LEU 169.A N PHE 165.A O no hydrogen 2.857 N/A LYS 170.A N LEU 166.A O no hydrogen 2.921 N/A THR 171.A N ILE 167.A O no hydrogen 2.968 N/A THR 171.A OG1 ILE 167.A O no hydrogen 2.955 N/A ARG 172.A N ASP 168.A O no hydrogen 2.860 N/A ARG 172.A NE ASP 168.A OD1 no hydrogen 3.074 N/A ARG 172.A NH1 SER 230.A O no hydrogen 2.908 N/A ARG 172.A NH2 ASP 168.A OD1 no hydrogen 3.529 N/A ARG 172.A NH2 ASP 168.A OD2 no hydrogen 2.749 N/A ARG 172.A NH2 SER 230.A O no hydrogen 3.203 N/A TYR 173.A N LEU 169.A O no hydrogen 3.219 N/A ILE 181.A N ASN 178.A O no hydrogen 3.273 N/A LEU 182.A N PRO 179.A O no hydrogen 2.914 N/A ARG 183.A N GLU 180.A O no hydrogen 2.917 N/A ARG 183.A NE GLU 180.A OE1 no hydrogen 3.174 N/A ARG 183.A NE GLU 180.A OE2 no hydrogen 3.084 N/A ARG 183.A NH1 GLU 163.A OE2 no hydrogen 2.396 N/A ARG 183.A NH2 GLU 163.A OE1 no hydrogen 2.708 N/A ARG 183.A NH2 GLU 180.A OE2 no hydrogen 3.289 N/A ALA 186.A N LEU 182.A O no hydrogen 3.151 N/A ASP 187.A N ARG 183.A O no hydrogen 2.636 N/A ASP 188.A N LYS 184.A O no hydrogen 2.695 N/A PHE 189.A N THR 185.A O no hydrogen 2.675 N/A LEU 190.A N ALA 186.A O no hydrogen 2.663 N/A ASN 191.A N ASP 187.A O no hydrogen 2.814 N/A ARG 192.A N ASP 188.A O no hydrogen 3.047 N/A ILE 193.A N PHE 189.A O no hydrogen 2.745 N/A ALA 194.A N LEU 190.A O no hydrogen 2.862 N/A ALA 194.A N ASN 191.A O no hydrogen 2.942 N/A LEU 195.A N ARG 192.A O no hydrogen 2.939 N/A THR 196.A N ILE 193.A O no hydrogen 3.374 N/A THR 196.A OG1 ILE 193.A O no hydrogen 3.035 N/A ALA 198.A N THR 196.A OG1 no hydrogen 3.121 N/A LEU 200.A N ASP 197.A O no hydrogen 2.954 N/A LEU 201.A N ALA 198.A O no hydrogen 2.941 N/A TYR 202.A N ALA 198.A O no hydrogen 2.913 N/A THR 203.A N GLN 206.A OE1 no hydrogen 3.044 N/A THR 203.A OG1 SER 205.A OG no hydrogen 2.989 N/A SER 205.A OG THR 203.A OG1 no hydrogen 2.989 N/A GLN 206.A N THR 203.A OG1 no hydrogen 2.950 N/A ILE 207.A N THR 203.A O no hydrogen 2.918 N/A ALA 208.A N PRO 204.A O no hydrogen 2.908 N/A LEU 209.A N SER 205.A O no hydrogen 2.898 N/A THR 210.A N GLN 206.A O no hydrogen 2.871 N/A THR 210.A OG1 GLN 206.A O no hydrogen 2.557 N/A ALA 211.A N ILE 207.A O no hydrogen 2.935 N/A ILE 212.A N ALA 208.A O no hydrogen 2.949 N/A LEU 213.A N LEU 209.A O no hydrogen 2.883 N/A SER 214.A N THR 210.A O no hydrogen 2.853 N/A SER 214.A OG THR 210.A O no hydrogen 2.665 N/A SER 215.A N ALA 211.A O no hydrogen 2.948 N/A SER 215.A OG LEU 182.A O no hydrogen 2.830 N/A ALA 216.A N ILE 212.A O no hydrogen 2.898 N/A SER 217.A N LEU 213.A O no hydrogen 2.868 N/A SER 217.A OG LEU 213.A O no hydrogen 2.885 N/A ARG 218.A N SER 214.A O no hydrogen 2.902 N/A ALA 219.A N SER 215.A O no hydrogen 2.917 N/A GLY 220.A N SER 217.A O no hydrogen 3.010 N/A ILE 221.A N ALA 216.A O no hydrogen 2.790 N/A GLU 224.A N GLU 224.A OE1 no hydrogen 2.502 N/A TYR 226.A OH ASP 168.A OD2 no hydrogen 2.609 N/A SER 228.A N GLU 224.A O no hydrogen 2.941 N/A SER 228.A OG GLU 224.A O no hydrogen 3.097 N/A GLU 229.A N SER 225.A O no hydrogen 2.684 N/A SER 230.A N SER 225.A O no hydrogen 3.447 N/A LEU 231.A N TYR 226.A O no hydrogen 2.815 N/A MET 232.A N GLU 229.A O no hydrogen 3.087 N/A LEU 233.A N LEU 227.A O no hydrogen 3.228 N/A LYS 234.A NZ GLU 235.A OE2 no hydrogen 3.518 N/A GLU 235.A N MET 232.A O no hydrogen 3.310 N/A THR 238.A OG1 ASN 236.A OD1 no hydrogen 2.757 N/A CYS 239.A N ASN 236.A OD1 no hydrogen 3.154 N/A LEU 240.A N ASN 236.A O no hydrogen 3.426 N/A SER 241.A N ARG 237.A O no hydrogen 2.957 N/A SER 241.A OG ARG 237.A O no hydrogen 3.236 N/A SER 241.A OG THR 238.A O no hydrogen 2.872 N/A GLN 242.A N THR 238.A O no hydrogen 2.874 N/A LEU 243.A N CYS 239.A O no hydrogen 2.916 N/A LEU 244.A N LEU 240.A O no hydrogen 2.941 N/A ASP 245.A N SER 241.A O no hydrogen 2.990 N/A MET 247.A N LEU 243.A O no hydrogen 3.016 N/A LYS 248.A N LEU 244.A O no hydrogen 2.922 N/A SER 249.A N ASP 245.A O no hydrogen 2.871 N/A SER 249.A OG TYR 202.A OH no hydrogen 3.413 N/A SER 249.A OG ASP 245.A O no hydrogen 2.378 N/A SER 249.A OG ILE 246.A O no hydrogen 2.949 N/A MET 250.A N ILE 246.A O no hydrogen 2.931 N/A ARG 251.A N MET 247.A O no hydrogen 2.930 N/A ASN 252.A N LYS 248.A O no hydrogen 2.915 N/A LEU 253.A N SER 249.A O no hydrogen 2.857 N/A VAL 254.A N MET 250.A O no hydrogen 2.991 N/A LYS 255.A N ARG 251.A O no hydrogen 2.872 N/A LYS 256.A N ASN 252.A O no hydrogen 2.897 N/A GLU 263.A N GLU 263.A OE1 no hydrogen 2.703 N/A VAL 265.A N ARG 261.A O no hydrogen 2.946 N/A ALA 266.A N SER 262.A O no hydrogen 2.902 N/A VAL 267.A N GLU 263.A O no hydrogen 2.925 N/A LEU 268.A N GLU 264.A O no hydrogen 3.006 N/A LYS 269.A N VAL 265.A O no hydrogen 2.795 N/A LYS 269.A NZ TYR 54.A OH no hydrogen 2.852 N/A GLN 270.A N ALA 266.A O no hydrogen 2.979 N/A LYS 271.A N VAL 267.A O no hydrogen 2.935 N/A LYS 271.A NZ PHE 42.A O no hydrogen 2.982 N/A LYS 271.A NZ GLU 47.A OE2 no hydrogen 2.752 N/A LEU 272.A N LEU 268.A O no hydrogen 2.849 N/A GLU 273.A N LYS 269.A O no hydrogen 2.899 N/A ARG 274.A N GLN 270.A O no hydrogen 2.930 N/A CYS 275.A N LYS 271.A O no hydrogen 2.912 N/A CYS 275.A SG VAL 41.A O no hydrogen 3.068 N/A HIS 276.A N LEU 272.A O no hydrogen 2.913 N/A SER 277.A N GLU 273.A O no hydrogen 2.892 N/A SER 277.A OG GLU 273.A O no hydrogen 3.471 N/A ALA 278.A N ARG 274.A O no hydrogen 2.896 N/A