Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8pkx_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LEU 4.A N THR 286.A O no hydrogen 2.919 N/A ILE 5.A N TYR 22.A O no hydrogen 2.944 N/A TYR 6.A N ALA 284.A O no hydrogen 2.809 N/A TYR 6.A OH MET 287.A O no hydrogen 2.590 N/A THR 7.A N GLU 20.A O no hydrogen 2.761 N/A ALA 8.A N GLY 282.A O no hydrogen 2.774 N/A GLY 9.A N TYR 18.A O no hydrogen 2.792 N/A GLY 10.A N ARG 39.A O no hydrogen 2.822 N/A TYR 11.A N SER 279.A O no hydrogen 2.693 N/A PHE 12.A N GLN 14.A O.A no hydrogen 3.012 N/A PHE 12.A N GLN 14.A O.B no hydrogen 2.957 N/A SER 15.A N ASN 59.A O no hydrogen 2.777 N/A SER 15.A OG SER 40.A OG no hydrogen 2.937 N/A SER 15.A OG ARG 57.A O no hydrogen 2.958 N/A LEU 16.A N GLY 10.A O no hydrogen 2.807 N/A SER 17.A OG.B ASP 34.A OD2 no hydrogen 3.220 N/A GLU 20.A N THR 7.A O no hydrogen 3.050 N/A ALA 21.A N LEU 30.A O no hydrogen 2.919 N/A TYR 22.A N ILE 5.A O no hydrogen 2.767 N/A ASN 23.A N THR 28.A O no hydrogen 2.970 N/A SER 25.A N ASN 23.A OD1 no hydrogen 2.863 N/A SER 25.A OG.B ASN 23.A OD1 no hydrogen 2.549 N/A ASP 26.A N ASN 23.A OD1 no hydrogen 3.022 N/A GLY 27.A N ASN 23.A O no hydrogen 2.740 N/A THR 28.A N ASP 26.A OD1 no hydrogen 3.003 N/A THR 28.A OG1 ASP 26.A OD1 no hydrogen 2.746 N/A TRP 29.A NE1 ARG 273.A O.A no hydrogen 2.703 N/A LEU 30.A N ALA 21.A O no hydrogen 2.832 N/A ARG 31.A NH2 ASP 34.A OD1 no hydrogen 3.076 N/A LEU 32.A N LEU 19.A O no hydrogen 2.856 N/A ALA 33.A N ASN 78.A OD1 no hydrogen 3.049 N/A LEU 35.A N SER 17.A O no hydrogen 2.880 N/A GLN 36.A NE2.B ASP 71.A OD1 no hydrogen 2.982 N/A ARG 39.A N LEU 16.A O no hydrogen 3.030 N/A ARG 39.A NE GLY 55.A O no hydrogen 3.056 N/A ARG 39.A NH1 ASP 71.A OD2 no hydrogen 2.730 N/A ARG 39.A NH2 ALA 53.A O no hydrogen 3.014 N/A ARG 39.A NH2 GLY 55.A O no hydrogen 3.025 N/A SER 40.A N ARG 57.A O no hydrogen 2.861 N/A SER 40.A OG SER 15.A OG no hydrogen 2.937 N/A SER 40.A OG ARG 57.A O no hydrogen 3.433 N/A GLY 41.A N GLY 280.A O no hydrogen 2.842 N/A ALA 43.A N VAL 54.A O no hydrogen 3.052 N/A CYS 45.A N TYR 52.A O no hydrogen 3.160 N/A VAL 47.A N LEU 50.A O no hydrogen 3.069 N/A LEU 50.A N VAL 47.A O no hydrogen 3.080 N/A LEU 51.A N TYR 73.A O no hydrogen 2.995 N/A TYR 52.A N CYS 45.A O no hydrogen 2.760 N/A ALA 53.A N ASP 71.A O no hydrogen 2.808 N/A VAL 54.A N ALA 43.A O no hydrogen 2.946 N/A GLY 55.A N ALA 69.A O no hydrogen 2.969 N/A GLY 56.A N ARG 90.A O no hydrogen 2.843 N/A ARG 57.A NE ASN 59.A OD1 no hydrogen 2.746 N/A ARG 57.A NH1 ASP 66.A OD1 no hydrogen 2.799 N/A ASN 58.A N THR 65.A O no hydrogen 2.780 N/A ASN 59.A N SER 15.A OG no hydrogen 2.828 N/A ASN 59.A ND2 SER 15.A OG no hydrogen 3.321 N/A SER 60.A N ASN 64.A OD1 no hydrogen 3.282 N/A SER 60.A OG.A GLY 63.A O no hydrogen 2.846 N/A SER 60.A OG.B ASN 58.A OD1 no hydrogen 2.630 N/A ASP 62.A N SER 60.A OG.A no hydrogen 3.030 N/A GLY 63.A N SER 60.A O no hydrogen 3.108 N/A GLY 63.A N SER 60.A OG.A no hydrogen 3.196 N/A THR 65.A N ASN 58.A O no hydrogen 3.053 N/A SER 67.A N GLY 56.A O no hydrogen 2.793 N/A ALA 69.A N SER 67.A OG no hydrogen 2.943 N/A ASP 71.A N ALA 53.A O no hydrogen 3.011 N/A CYS 72.A N.A SER 81.A O no hydrogen 2.792 N/A CYS 72.A N.B SER 81.A O no hydrogen 2.824 N/A CYS 72.A SG.B SER 81.A O no hydrogen 3.591 N/A TYR 73.A N LEU 51.A O no hydrogen 2.644 N/A TYR 73.A OH ASN 78.A OD1 no hydrogen 2.506 N/A ASN 74.A N GLN 79.A O no hydrogen 3.055 N/A MET 76.A N ASN 74.A OD1 no hydrogen 2.937 N/A THR 77.A N ASN 74.A O no hydrogen 3.165 N/A THR 77.A OG1 ASN 74.A O no hydrogen 3.392 N/A ASN 78.A N ASN 74.A O no hydrogen 2.769 N/A TRP 80.A NE1 ALA 33.A O no hydrogen 2.958 N/A SER 81.A N CYS 72.A O.A no hydrogen 2.785 N/A SER 81.A N CYS 72.A O.B no hydrogen 2.866 N/A CYS 83.A N LEU 70.A O no hydrogen 2.806 N/A CYS 83.A SG TYR 120.A OH no hydrogen 3.801 N/A ALA 84.A N ASP 125.A OD1 no hydrogen 2.902 N/A MET 86.A N SER 68.A O no hydrogen 2.822 N/A SER 87.A N GLU 118.A OE1 no hydrogen 2.833 N/A SER 87.A N GLU 118.A OE2 no hydrogen 3.305 N/A SER 87.A OG GLU 118.A OE1 no hydrogen 3.385 N/A SER 87.A OG GLU 118.A OE2 no hydrogen 2.752 N/A ARG 90.A N SER 67.A O no hydrogen 3.069 N/A ARG 90.A NE GLU 118.A OE2 no hydrogen 3.230 N/A ARG 90.A NH1 GLY 106.A O no hydrogen 2.880 N/A ARG 90.A NH1 SER 116.A O no hydrogen 3.011 N/A ARG 90.A NH1 SER 116.A OG no hydrogen 3.337 N/A ARG 90.A NH2 SER 116.A OG no hydrogen 2.878 N/A ARG 90.A NH2 GLU 118.A OE2 no hydrogen 2.835 N/A ASN 91.A N SER 108.A O no hydrogen 2.782 N/A ILE 93.A N GLY 41.A O no hydrogen 3.398 N/A GLY 94.A N VAL 105.A O no hydrogen 3.193 N/A GLY 96.A N TYR 103.A O no hydrogen 3.099 N/A ILE 98.A N HIS 101.A O no hydrogen 2.975 N/A HIS 101.A N ILE 98.A O no hydrogen 3.011 N/A ILE 102.A N TYR 120.A O no hydrogen 3.047 N/A TYR 103.A N GLY 96.A O no hydrogen 2.747 N/A ALA 104.A N GLU 118.A O no hydrogen 2.789 N/A VAL 105.A N GLY 94.A O no hydrogen 2.834 N/A GLY 106.A N SER 116.A O no hydrogen 3.196 N/A GLY 107.A N ARG 137.A O no hydrogen 2.907 N/A SER 108.A N ASN 91.A O no hydrogen 2.756 N/A HIS 109.A N ILE 112.A O no hydrogen 2.859 N/A GLY 110.A N ASP 66.A OD2 no hydrogen 2.723 N/A ILE 112.A N HIS 109.A O no hydrogen 2.804 N/A HIS 114.A N GLY 107.A O no hydrogen 2.892 N/A HIS 114.A NE2 PRO 89.A O no hydrogen 2.801 N/A GLU 118.A N ALA 104.A O no hydrogen 3.032 N/A ARG 119.A N HIS 128.A O no hydrogen 2.813 N/A TYR 120.A N ILE 102.A O no hydrogen 2.675 N/A TYR 120.A OH ASP 125.A OD1 no hydrogen 2.494 N/A GLU 121.A N GLU 126.A O no hydrogen 2.904 N/A ARG 124.A N GLU 121.A O no hydrogen 3.050 N/A ARG 124.A NE GLU 126.A OE2 no hydrogen 3.447 N/A ARG 124.A NH2 GLU 126.A OE2 no hydrogen 3.507 N/A ASP 125.A N PRO 122.A O no hydrogen 3.267 N/A TRP 127.A NE1 ALA 84.A O no hydrogen 2.853 N/A HIS 128.A N ARG 119.A O no hydrogen 2.863 N/A HIS 128.A NE2 GLU 126.A OE2 no hydrogen 2.861 N/A VAL 130.A N VAL 117.A O no hydrogen 2.935 N/A ALA 131.A N ASN 172.A OD1 no hydrogen 2.974 N/A MET 133.A N ASN 115.A O no hydrogen 2.732 N/A LEU 134.A N GLU 165.A OE1 no hydrogen 2.768 N/A THR 135.A OG1 GLU 165.A OE2 no hydrogen 2.940 N/A ARG 136.A NH1 HIS 113.A O no hydrogen 2.845 N/A ARG 137.A N HIS 114.A O no hydrogen 3.115 N/A ARG 137.A NE GLU 165.A OE2 no hydrogen 2.999 N/A ARG 137.A NH1 GLY 153.A O no hydrogen 2.882 N/A ARG 137.A NH1 SER 163.A O no hydrogen 2.962 N/A ARG 137.A NH1 SER 163.A OG no hydrogen 3.142 N/A ARG 137.A NH2 SER 163.A OG no hydrogen 2.905 N/A ARG 137.A NH2 GLU 165.A OE2 no hydrogen 2.889 N/A ILE 138.A N PHE 155.A O no hydrogen 2.899 N/A GLY 139.A N ARG 92.A O no hydrogen 2.857 N/A GLY 141.A N VAL 152.A O no hydrogen 2.987 N/A ALA 143.A N TYR 150.A O no hydrogen 3.091 N/A LEU 145.A N LEU 148.A O no hydrogen 2.982 N/A LEU 148.A N LEU 145.A O no hydrogen 2.944 N/A LEU 149.A N TYR 167.A O no hydrogen 3.182 N/A TYR 150.A N ALA 143.A O no hydrogen 2.827 N/A ALA 151.A N GLU 165.A O no hydrogen 2.855 N/A VAL 152.A N GLY 141.A O no hydrogen 2.758 N/A GLY 153.A N SER 163.A O no hydrogen 2.925 N/A GLY 154.A N ARG 184.A O no hydrogen 2.817 N/A PHE 155.A N ILE 138.A O no hydrogen 2.805 N/A ASP 156.A N ASN 159.A O no hydrogen 2.957 N/A THR 158.A N ASP 156.A OD1 no hydrogen 2.713 N/A ASN 159.A N ASP 156.A OD1 no hydrogen 2.687 N/A ARG 160.A NE SER 185.A OG.A no hydrogen 3.298 N/A LEU 161.A N GLY 154.A O no hydrogen 2.939 N/A ASN 162.A ND2 MET 180.A O no hydrogen 3.318 N/A GLU 165.A N ALA 151.A O no hydrogen 2.957 N/A CYS 166.A N ARG 175.A O no hydrogen 2.728 N/A TYR 167.A N LEU 149.A O no hydrogen 2.644 N/A TYR 167.A OH ASN 172.A OD1 no hydrogen 2.727 N/A TYR 168.A N GLU 173.A O no hydrogen 2.946 N/A ASN 172.A N PRO 169.A O no hydrogen 3.320 N/A TRP 174.A NE1 ALA 131.A O no hydrogen 2.931 N/A ARG 175.A N CYS 166.A O no hydrogen 2.868 N/A ILE 177.A N ALA 164.A O no hydrogen 3.029 N/A THR 178.A OG1 ALA 219.A O no hydrogen 2.960 N/A MET 180.A N ASN 162.A O no hydrogen 2.839 N/A ASN 181.A N GLU 212.A OE1 no hydrogen 2.805 N/A ASN 181.A ND2 GLU 212.A OE1 no hydrogen 2.931 N/A ASN 181.A ND2 TRP 221.A O no hydrogen 3.179 N/A THR 182.A N GLU 212.A OE2 no hydrogen 3.127 N/A THR 182.A OG1 GLU 212.A OE2 no hydrogen 3.420 N/A ARG 184.A N LEU 161.A O no hydrogen 3.011 N/A ARG 184.A NE GLU 212.A OE2 no hydrogen 3.282 N/A ARG 184.A NH1 GLY 200.A O no hydrogen 2.935 N/A ARG 184.A NH1 SER 210.A O no hydrogen 2.932 N/A ARG 184.A NH1 SER 210.A OG no hydrogen 3.326 N/A ARG 184.A NH2 SER 210.A OG no hydrogen 2.977 N/A ARG 184.A NH2 GLU 212.A OE2 no hydrogen 2.904 N/A SER 185.A N TYR 202.A O no hydrogen 2.801 N/A SER 185.A OG.A TYR 202.A O no hydrogen 3.346 N/A SER 185.A OG.B ILE 138.A O no hydrogen 3.531 N/A GLY 186.A N GLY 139.A O no hydrogen 2.892 N/A GLY 188.A N ALA 199.A O no hydrogen 2.875 N/A CYS 190.A N TYR 197.A O no hydrogen 3.082 N/A LEU 192.A N CYS 195.A O no hydrogen 2.830 N/A CYS 195.A N LEU 192.A O no hydrogen 3.024 N/A CYS 195.A SG HIS 193.A O no hydrogen 3.898 N/A ILE 196.A N TYR 214.A O no hydrogen 3.248 N/A TYR 197.A N CYS 190.A O no hydrogen 2.746 N/A ALA 198.A N GLU 212.A O no hydrogen 2.789 N/A ALA 199.A N GLY 188.A O no hydrogen 2.814 N/A GLY 200.A N SER 210.A O no hydrogen 2.989 N/A GLY 201.A N ARG 231.A O no hydrogen 2.803 N/A TYR 202.A N SER 185.A O no hydrogen 2.824 N/A ASP 203.A N ASP 206.A O no hydrogen 3.244 N/A GLN 205.A N ASP 203.A OD1 no hydrogen 2.783 N/A ASP 206.A N ASP 203.A OD1 no hydrogen 2.769 N/A LEU 208.A N GLY 201.A O no hydrogen 2.842 N/A GLU 212.A N ALA 198.A O no hydrogen 2.935 N/A ARG 213.A N THR 222.A O no hydrogen 2.848 N/A ARG 213.A NH1 TYR 197.A OH no hydrogen 3.240 N/A TYR 214.A N ILE 196.A O no hydrogen 2.712 N/A ASP 215.A N THR 220.A O no hydrogen 3.105 N/A ALA 217.A N ASP 215.A OD1 no hydrogen 3.182 N/A THR 218.A OG1 ASP 215.A OD2 no hydrogen 3.345 N/A THR 220.A OG1 THR 218.A O no hydrogen 2.805 N/A TRP 221.A NE1 THR 178.A O no hydrogen 2.854 N/A THR 222.A N ARG 213.A O no hydrogen 2.883 N/A VAL 224.A N VAL 211.A O no hydrogen 2.877 N/A ALA 225.A N ASP 266.A OD1 no hydrogen 3.005 N/A MET 227.A N ASN 209.A O no hydrogen 2.715 N/A LYS 228.A N GLU 259.A OE1 no hydrogen 2.646 N/A HIS 229.A N GLU 259.A OE2 no hydrogen 3.064 N/A HIS 229.A NE2 GLU 270.A OE1 no hydrogen 3.060 N/A ARG 230.A NH1 GLN 207.A O no hydrogen 2.836 N/A ARG 231.A N LEU 208.A O no hydrogen 2.992 N/A ARG 231.A NE HIS 229.A O no hydrogen 3.470 N/A ARG 231.A NH1 GLY 247.A O no hydrogen 2.855 N/A ARG 231.A NH1 SER 257.A O no hydrogen 2.976 N/A ARG 231.A NH2 SER 257.A OG no hydrogen 2.969 N/A ARG 231.A NH2 GLU 259.A OE2 no hydrogen 2.720 N/A SER 232.A N TYR 249.A O no hydrogen 2.903 N/A SER 232.A OG SER 185.A O no hydrogen 3.500 N/A ALA 233.A N GLY 186.A O no hydrogen 2.853 N/A GLY 235.A N LEU 246.A O no hydrogen 2.981 N/A THR 237.A N TYR 244.A O no hydrogen 2.957 N/A HIS 239.A N ARG 242.A O no hydrogen 2.919 N/A HIS 239.A NE2 ARG 3.A O no hydrogen 3.218 N/A ARG 242.A N HIS 239.A O no hydrogen 3.097 N/A ILE 243.A N TYR 261.A O no hydrogen 3.168 N/A TYR 244.A N THR 237.A O no hydrogen 2.781 N/A VAL 245.A N.A GLU 259.A O no hydrogen 2.860 N/A VAL 245.A N.B GLU 259.A O no hydrogen 2.851 N/A LEU 246.A N GLY 235.A O no hydrogen 2.779 N/A GLY 247.A N SER 257.A O no hydrogen 3.036 N/A GLY 248.A N ARG 278.A O no hydrogen 2.883 N/A TYR 249.A N SER 232.A O no hydrogen 2.845 N/A ASP 250.A N THR 253.A O no hydrogen 3.186 N/A HIS 252.A N.A ASP 250.A OD1 no hydrogen 2.904 N/A HIS 252.A N.B ASP 250.A OD1 no hydrogen 2.940 N/A THR 253.A N ASP 250.A OD1 no hydrogen 2.772 N/A LEU 255.A N GLY 248.A O no hydrogen 2.769 N/A SER 257.A OG GLU 270.A OE1 no hydrogen 2.808 N/A VAL 258.A N THR 272.A O no hydrogen 3.151 N/A GLU 259.A N VAL 245.A O.A no hydrogen 3.037 N/A GLU 259.A N VAL 245.A O.B no hydrogen 3.015 N/A CYS 260.A N SER 269.A O no hydrogen 2.731 N/A CYS 260.A SG ILE 243.A O no hydrogen 3.737 N/A TYR 261.A N ILE 243.A O no hydrogen 2.764 N/A TYR 261.A OH ASP 266.A OD1 no hydrogen 2.609 N/A ASP 262.A N THR 267.A O no hydrogen 2.935 N/A ASP 264.A N ASP 262.A OD1 no hydrogen 3.125 N/A THR 265.A N ASP 262.A O no hydrogen 3.357 N/A THR 265.A OG1 ASP 262.A O no hydrogen 3.514 N/A THR 265.A OG1 ASP 262.A OD2 no hydrogen 3.125 N/A THR 265.A OG1 THR 267.A OG1.A no hydrogen 2.443 N/A THR 265.A OG1 THR 267.A OG1.B no hydrogen 3.252 N/A THR 267.A N ASP 262.A O no hydrogen 3.376 N/A THR 267.A OG1.A THR 265.A OG1 no hydrogen 2.443 N/A THR 267.A OG1.B THR 265.A O no hydrogen 3.055 N/A THR 267.A OG1.B THR 265.A OG1 no hydrogen 3.252 N/A TRP 268.A NE1 ALA 225.A O no hydrogen 2.839 N/A SER 269.A N CYS 260.A O no hydrogen 2.985 N/A VAL 271.A N VAL 258.A O no hydrogen 2.954 N/A THR 272.A OG1 ARG 273.A O.A no hydrogen 3.204 N/A ARG 273.A NE.B ASP 256.A OD1 no hydrogen 2.956 N/A ARG 273.A NE.B ASP 256.A OD2 no hydrogen 3.198 N/A ARG 273.A NH1.B ASP 256.A OD1 no hydrogen 3.548 N/A ARG 273.A NH1.B ASP 256.A OD2 no hydrogen 2.923 N/A ARG 273.A NH2.A ASP 256.A OD1 no hydrogen 3.193 N/A MET 274.A N ASP 256.A O no hydrogen 2.798 N/A THR 275.A OG1 GLU 20.A OE1 no hydrogen 2.642 N/A THR 275.A OG1 GLU 20.A OE2 no hydrogen 3.218 N/A ARG 278.A N LEU 255.A O no hydrogen 3.097 N/A ARG 278.A NE SER 276.A O no hydrogen 3.031 N/A ARG 278.A NH1 GLU 20.A OE2 no hydrogen 2.824 N/A ARG 278.A NH2 GLU 20.A OE2 no hydrogen 2.772 N/A ARG 278.A NH2 SER 276.A O no hydrogen 3.313 N/A ARG 278.A NH2 SER 276.A OG no hydrogen 3.087 N/A SER 279.A N TYR 11.A O no hydrogen 3.052 N/A GLY 280.A N ALA 233.A O no hydrogen 2.851 N/A GLY 282.A N ALA 8.A O no hydrogen 3.006 N/A ALA 284.A N TYR 6.A O no hydrogen 3.121 N/A THR 286.A N LEU 4.A O no hydrogen 3.332 N/A THR 286.A OG1 GLY 49.A O no hydrogen 3.048 N/A MET 287.A N THR 286.A OG1 no hydrogen 2.745 N/A GLU 288.A N GLY 2.A O no hydrogen 3.049 N/A SER 290.A N PRO 75.A O no hydrogen 3.138 N/A