Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8qlq_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ASN 2.A N THR 1.A O no hydrogen 2.253 N/A GLU 8.A N ASP 6.A OD1 no hydrogen 2.842 N/A GLU 9.A N ASP 6.A O no hydrogen 3.068 N/A LEU 10.A N ASP 6.A O no hydrogen 3.090 N/A PHE 11.A N PRO 7.A O no hydrogen 2.798 N/A THR 12.A N ILE 29.A O no hydrogen 2.899 N/A THR 12.A OG1 ASN 31.A OD1 no hydrogen 2.721 N/A LEU 14.A N LYS 27.A O no hydrogen 2.655 N/A GLU 15.A N GLU 15.A OE1 no hydrogen 2.799 N/A ILE 17.A N VAL 25.A O no hydrogen 2.876 N/A GLY 20.A N GLY 23.A O no hydrogen 2.949 N/A SER 21.A OG ASP 129.A OD2 no hydrogen 2.569 N/A GLY 23.A N GLY 20.A O no hydrogen 3.439 N/A VAL 25.A N GLY 18.A O no hydrogen 2.929 N/A PHE 26.A N ILE 39.A O no hydrogen 2.734 N/A LYS 27.A N GLU 15.A O no hydrogen 2.911 N/A LYS 27.A NZ GLU 15.A OE2 no hydrogen 3.073 N/A GLY 28.A N VAL 37.A O no hydrogen 2.821 N/A ILE 29.A N THR 12.A O no hydrogen 2.898 N/A ASP 30.A N LYS 35.A O no hydrogen 2.869 N/A ASN 31.A N LEU 10.A O no hydrogen 2.843 N/A ASN 31.A ND2 GLU 9.A O no hydrogen 2.840 N/A ARG 32.A N ASP 30.A OD1 no hydrogen 2.852 N/A THR 33.A N ASP 30.A OD1 no hydrogen 3.203 N/A GLN 34.A N ASP 30.A O no hydrogen 2.571 N/A GLN 34.A NE2 ASN 31.A O no hydrogen 2.999 N/A VAL 37.A N GLY 28.A O no hydrogen 2.899 N/A ALA 38.A N MET 84.A O no hydrogen 2.813 N/A ILE 39.A N PHE 26.A O no hydrogen 2.826 N/A LYS 40.A N ILE 82.A O no hydrogen 2.878 N/A LYS 40.A NZ SER 21.A O no hydrogen 2.737 N/A LYS 40.A NZ ASP 147.A OD2 no hydrogen 2.731 N/A ILE 42.A N LEU 80.A O no hydrogen 2.931 N/A LEU 44.A N THR 78.A O no hydrogen 2.776 N/A GLU 45.A N ASP 43.A OD1 no hydrogen 3.197 N/A ALA 47.A N LEU 44.A O no hydrogen 2.914 N/A ILE 52.A N GLU 48.A O no hydrogen 3.412 N/A GLN 53.A N ILE 49.A O no hydrogen 3.020 N/A GLN 53.A NE2 SER 73.A O no hydrogen 3.433 N/A GLN 53.A NE2 SER 73.A OG no hydrogen 3.102 N/A GLN 54.A N GLU 50.A O no hydrogen 2.893 N/A GLU 55.A N ASP 51.A O no hydrogen 3.079 N/A ILE 56.A N ILE 52.A O no hydrogen 2.920 N/A THR 57.A N GLN 53.A O no hydrogen 2.963 N/A THR 57.A OG1 GLN 53.A O no hydrogen 3.266 N/A VAL 58.A N GLN 54.A O no hydrogen 3.063 N/A LEU 59.A N GLU 55.A O no hydrogen 2.783 N/A SER 60.A N ILE 56.A O no hydrogen 2.853 N/A SER 60.A N THR 57.A O no hydrogen 3.232 N/A SER 60.A OG ILE 56.A O no hydrogen 2.727 N/A GLN 61.A N VAL 58.A O no hydrogen 3.057 N/A CYS 62.A N LEU 59.A O no hydrogen 3.059 N/A ASP 63.A N TYR 119.A OH no hydrogen 2.865 N/A TYR 66.A N SER 64.A OG no hydrogen 3.059 N/A VAL 67.A N SER 64.A O no hydrogen 3.388 N/A THR 68.A N LEU 145.A O no hydrogen 2.866 N/A THR 68.A OG1 LEU 145.A O no hydrogen 3.101 N/A LYS 69.A N GLU 85.A OE1 no hydrogen 2.986 N/A LYS 69.A NZ ASP 63.A OD1 no hydrogen 3.310 N/A TYR 70.A OH PHE 148.A O no hydrogen 2.729 N/A TYR 71.A N ILE 83.A O no hydrogen 2.828 N/A GLY 72.A N SER 60.A OG no hydrogen 3.134 N/A TYR 74.A N TRP 81.A O no hydrogen 2.805 N/A LYS 76.A N LYS 79.A O no hydrogen 2.813 N/A THR 78.A OG1 ASP 43.A OD1 no hydrogen 2.896 N/A LYS 79.A N LYS 76.A O no hydrogen 2.937 N/A LYS 79.A NZ ASP 43.A OD2 no hydrogen 2.995 N/A LYS 79.A NZ THR 78.A OG1 no hydrogen 3.313 N/A LEU 80.A N ILE 42.A O no hydrogen 2.801 N/A TRP 81.A N TYR 74.A O no hydrogen 2.825 N/A ILE 82.A N LYS 40.A O no hydrogen 2.765 N/A ILE 83.A N GLY 72.A O no hydrogen 3.102 N/A MET 84.A N ALA 38.A O no hydrogen 2.776 N/A GLU 85.A N LYS 69.A O no hydrogen 2.878 N/A GLY 89.A N LEU 137.A O no hydrogen 2.825 N/A SER 91.A N ASP 94.A OD2 no hydrogen 2.984 N/A ALA 92.A N VAL 135.A O no hydrogen 2.794 N/A LEU 93.A N ALA 132.A O no hydrogen 3.266 N/A ASP 94.A N SER 91.A OG no hydrogen 2.929 N/A LEU 95.A N SER 91.A O no hydrogen 2.916 N/A LEU 96.A N LEU 93.A O no hydrogen 3.087 N/A GLU 97.A N ASP 94.A O no hydrogen 3.166 N/A GLY 99.A N LEU 96.A O no hydrogen 3.289 N/A ASP 102.A N GLN 105.A OE1 no hydrogen 2.966 N/A THR 104.A OG1 ASN 262.A O no hydrogen 3.566 N/A GLN 105.A N ASP 102.A OD1 no hydrogen 2.779 N/A ILE 106.A N ASP 102.A O no hydrogen 2.967 N/A ALA 107.A N GLU 103.A O no hydrogen 2.883 N/A THR 108.A N THR 104.A O no hydrogen 2.897 N/A THR 108.A OG1 THR 104.A O no hydrogen 2.641 N/A THR 108.A OG1 LYS 264.A O no hydrogen 3.521 N/A ILE 109.A N GLN 105.A O no hydrogen 2.976 N/A LEU 110.A N ILE 106.A O no hydrogen 2.856 N/A ARG 111.A N ALA 107.A O no hydrogen 2.900 N/A ARG 111.A NE GLU 112.A OE2 no hydrogen 3.383 N/A GLU 112.A N THR 108.A O no hydrogen 3.201 N/A ILE 113.A N ILE 109.A O no hydrogen 2.920 N/A LEU 114.A N LEU 110.A O no hydrogen 2.826 N/A LYS 115.A N ARG 111.A O no hydrogen 3.017 N/A GLY 116.A N GLU 112.A O no hydrogen 3.039 N/A LEU 117.A N ILE 113.A O no hydrogen 2.765 N/A ASP 118.A N LEU 114.A O no hydrogen 2.775 N/A TYR 119.A N LYS 115.A O no hydrogen 3.066 N/A LEU 120.A N GLY 116.A O no hydrogen 3.022 N/A HIS 121.A N LEU 117.A O no hydrogen 2.834 N/A HIS 121.A NE2 ASP 186.A OD2 no hydrogen 2.797 N/A SER 122.A N ASP 118.A O no hydrogen 2.933 N/A SER 122.A OG ASP 118.A O no hydrogen 3.390 N/A SER 122.A OG TYR 119.A O no hydrogen 2.656 N/A GLU 123.A N TYR 119.A O no hydrogen 3.067 N/A GLU 123.A N LEU 120.A O no hydrogen 3.011 N/A LYS 124.A N HIS 121.A O no hydrogen 2.965 N/A LYS 125.A N LEU 120.A O no hydrogen 2.877 N/A LYS 125.A NZ GLU 55.A OE2 no hydrogen 2.874 N/A HIS 127.A N ASP 186.A OD2 no hydrogen 2.801 N/A HIS 127.A NE2 ALA 146.A O no hydrogen 2.726 N/A ARG 128.A N ASP 186.A OD1 no hydrogen 2.847 N/A ARG 128.A NE TYR 181.A OH no hydrogen 3.456 N/A ARG 128.A NH1 ASP 156.A OD1 no hydrogen 2.842 N/A ARG 128.A NH2 ARG 128.A O no hydrogen 2.965 N/A ASP 129.A N HIS 127.A ND1 no hydrogen 3.029 N/A ALA 132.A N GLU 196.A OE1 no hydrogen 2.929 N/A ASN 134.A N LYS 131.A O no hydrogen 3.035 N/A ASN 134.A ND2 ASP 129.A O no hydrogen 2.898 N/A VAL 135.A N ALA 132.A O no hydrogen 3.176 N/A LEU 136.A N LYS 144.A O no hydrogen 2.862 N/A LEU 137.A N GLY 90.A O no hydrogen 2.944 N/A SER 138.A N GLU 142.A O no hydrogen 2.843 N/A SER 138.A OG GLU 142.A OE1 no hydrogen 2.559 N/A HIS 140.A N SER 138.A OG no hydrogen 3.156 N/A GLY 141.A N SER 138.A O no hydrogen 2.960 N/A GLU 142.A N SER 138.A OG no hydrogen 3.054 N/A LYS 144.A N LEU 136.A O no hydrogen 2.925 N/A LYS 144.A NZ GLU 85.A OE2 no hydrogen 3.044 N/A LEU 145.A N TYR 66.A O no hydrogen 2.892 N/A ALA 146.A N ASN 134.A O no hydrogen 2.902 N/A GLY 149.A N HIS 127.A O no hydrogen 2.906 N/A GLN 153.A N.A VAL 150.A O no hydrogen 3.006 N/A GLN 153.A N.A GLN 153.A OE1.A no hydrogen 2.504 N/A GLN 153.A NE2.A GLY 149.A O no hydrogen 3.091 N/A LEU 154.A N VAL 150.A O no hydrogen 3.354 N/A LEU 154.A N ALA 151.A O no hydrogen 3.139 N/A THR 155.A N GLY 152.A O no hydrogen 3.326 N/A THR 155.A OG1 ALA 151.A O no hydrogen 2.658 N/A ASP 156.A N GLY 152.A O no hydrogen 2.936 N/A ILE 159.A N THR 155.A O no hydrogen 2.856 N/A LYS 160.A N ASP 156.A O no hydrogen 2.977 N/A LYS 160.A NZ GLN 178.A OE1 no hydrogen 2.725 N/A ARG 161.A N THR 157.A O no hydrogen 2.959 N/A ASN 162.A N ILE 159.A O no hydrogen 3.230 N/A THR 163.A N GLN 158.A O no hydrogen 2.861 N/A THR 163.A OG1 GLN 158.A O no hydrogen 3.292 N/A TRP 170.A NE1 GLU 196.A OE1 no hydrogen 2.841 N/A MET 171.A N PRO 168.A O no hydrogen 3.081 N/A GLU 174.A N GLU 174.A OE1 no hydrogen 2.711 N/A VAL 175.A N ALA 172.A O no hydrogen 3.024 N/A ILE 176.A N ALA 172.A O no hydrogen 3.134 N/A LYS 177.A N PRO 173.A O no hydrogen 2.959 N/A GLN 178.A N VAL 175.A O no hydrogen 3.100 N/A GLN 178.A NE2 ASP 156.A OD1 no hydrogen 2.897 N/A GLN 178.A NE2 VAL 175.A O no hydrogen 2.881 N/A SER 179.A N GLU 174.A O no hydrogen 3.179 N/A SER 179.A OG GLU 174.A O no hydrogen 3.521 N/A TYR 181.A OH ASP 156.A OD2 no hydrogen 2.496 N/A LYS 184.A N ASP 182.A OD1 no hydrogen 2.840 N/A LYS 184.A NZ PRO 244.A O no hydrogen 3.389 N/A LYS 184.A NZ ARG 247.A O no hydrogen 2.784 N/A ALA 185.A N ASP 182.A O no hydrogen 2.969 N/A ASP 186.A N SER 183.A O no hydrogen 2.981 N/A ILE 187.A N LYS 184.A O no hydrogen 2.996 N/A TRP 188.A N LYS 184.A O no hydrogen 3.197 N/A SER 189.A N ALA 185.A O no hydrogen 3.108 N/A SER 189.A OG TRP 170.A O no hydrogen 2.572 N/A SER 189.A OG ALA 185.A O no hydrogen 3.388 N/A LEU 190.A N ASP 186.A O no hydrogen 2.760 N/A GLY 191.A N ILE 187.A O no hydrogen 3.074 N/A ILE 192.A N TRP 188.A O no hydrogen 3.085 N/A THR 193.A N SER 189.A O no hydrogen 2.870 N/A THR 193.A OG1 SER 189.A O no hydrogen 2.921 N/A ALA 194.A N LEU 190.A O no hydrogen 2.832 N/A ILE 195.A N GLY 191.A O no hydrogen 3.147 N/A GLU 196.A N ILE 192.A O no hydrogen 2.878 N/A LEU 197.A N THR 193.A O no hydrogen 2.779 N/A ALA 198.A N ALA 194.A O no hydrogen 3.038 N/A ARG 199.A N ILE 195.A O no hydrogen 2.805 N/A ARG 199.A NH1 GLU 225.A O no hydrogen 2.906 N/A GLY 200.A N GLU 196.A O no hydrogen 2.754 N/A SER 205.A OG PRO 202.A O no hydrogen 3.349 N/A GLU 206.A N GLU 206.A OE1 no hydrogen 2.594 N/A LEU 207.A N HIS 204.A O no hydrogen 2.987 N/A MET 210.A N HIS 208.A ND1 no hydrogen 3.002 N/A VAL 212.A N HIS 208.A O no hydrogen 3.053 N/A LEU 213.A N PRO 209.A O no hydrogen 2.953 N/A PHE 214.A N MET 210.A O no hydrogen 3.236 N/A LEU 215.A N LYS 211.A O no hydrogen 2.808 N/A ILE 216.A N VAL 212.A O no hydrogen 2.991 N/A LYS 218.A N LEU 215.A O no hydrogen 2.931 N/A LYS 218.A NZ PHE 214.A O no hydrogen 2.765 N/A ASN 219.A N LEU 215.A O no hydrogen 2.804 N/A TYR 228.A N GLY 226.A O no hydrogen 2.785 N/A TYR 228.A OH ALA 198.A O no hydrogen 2.882 N/A SER 229.A N GLU 103.A OE2 no hydrogen 2.889 N/A SER 229.A OG GLU 103.A OE1 no hydrogen 2.673 N/A LEU 232.A N SER 229.A OG no hydrogen 3.285 N/A LYS 233.A N SER 229.A O no hydrogen 2.992 N/A LYS 233.A NZ GLY 226.A O no hydrogen 3.074 N/A GLU 234.A N LYS 230.A O no hydrogen 2.864 N/A PHE 235.A N PRO 231.A O no hydrogen 2.829 N/A VAL 236.A N LEU 232.A O no hydrogen 3.053 N/A GLU 237.A N LYS 233.A O no hydrogen 2.928 N/A ALA 238.A N GLU 234.A O no hydrogen 2.898 N/A CYS 239.A N PHE 235.A O no hydrogen 3.200 N/A CYS 239.A SG PHE 235.A O no hydrogen 3.459 N/A LEU 240.A N VAL 236.A O no hydrogen 2.918 N/A LYS 242.A NZ PRO 217.A O no hydrogen 2.995 N/A LYS 242.A NZ ASN 219.A O no hydrogen 2.785 N/A GLU 243.A N ASN 241.A OD1 no hydrogen 2.919 N/A PHE 246.A N GLU 243.A O no hydrogen 3.025 N/A ARG 247.A N PRO 244.A O no hydrogen 3.101 N/A ARG 247.A NE ASN 241.A O no hydrogen 2.780 N/A ARG 247.A NH1 GLU 174.A OE2 no hydrogen 2.696 N/A ARG 247.A NH1 LYS 184.A O no hydrogen 2.874 N/A ARG 247.A NH2 GLU 174.A OE1 no hydrogen 2.906 N/A ARG 247.A NH2 GLU 174.A OE2 no hydrogen 3.476 N/A ARG 247.A NH2 ASN 241.A O no hydrogen 3.171 N/A ARG 247.A NH2 LYS 242.A O no hydrogen 3.279 N/A THR 249.A N GLU 252.A OE2 no hydrogen 2.922 N/A GLU 252.A N THR 249.A OG1 no hydrogen 3.140 N/A LEU 253.A N THR 249.A O no hydrogen 3.013 N/A LEU 254.A N ALA 250.A O no hydrogen 3.035 N/A LYS 255.A N GLU 252.A O no hydrogen 2.990 N/A HIS 256.A N LEU 253.A O no hydrogen 2.969 N/A PHE 258.A N HIS 256.A ND1 no hydrogen 2.998 N/A LEU 260.A N HIS 256.A O no hydrogen 2.972 N/A ARG 261.A N LYS 257.A O no hydrogen 2.984 N/A ASN 262.A N PHE 258.A O no hydrogen 3.101 N/A ASN 262.A ND2 PHE 258.A O no hydrogen 2.968 N/A ALA 263.A N ILE 259.A O no hydrogen 2.972 N/A LYS 264.A N THR 108.A OG1 no hydrogen 3.045 N/A TYR 268.A N LYS 265.A O no hydrogen 3.248 N/A LEU 269.A N THR 266.A O no hydrogen 2.936 N/A THR 270.A N SER 267.A O no hydrogen 3.168 N/A THR 270.A OG1 SER 267.A O no hydrogen 3.005 N/A GLU 271.A N TYR 268.A O no hydrogen 2.956 N/A LEU 272.A N LEU 269.A O no hydrogen 2.967 N/A ILE 273.A N LEU 269.A O no hydrogen 3.340 N/A ASP 274.A N THR 270.A O no hydrogen 2.923 N/A ALA 275.A N GLU 271.A O no hydrogen 2.994 N/A HIS 276.A N LEU 272.A O no hydrogen 3.216 N/A HIS 277.A N ILE 273.A O no hydrogen 3.055 N/A HIS 278.A N ASP 274.A O no hydrogen 2.934 N/A HIS 279.A N ALA 275.A O no hydrogen 2.842 N/A HIS 280.A N HIS 276.A O no hydrogen 3.018 N/A HIS 280.A N HIS 277.A O no hydrogen 3.146 N/A HIS 280.A NE2 GLU 97.A OE1 no hydrogen 3.052 N/A HIS 281.A N HIS 278.A O no hydrogen 3.435 N/A