Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8qxm_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LYS 3.A N LEU 15.A O no hydrogen 3.472 N/A ILE 5.A N ILE 13.A O no hydrogen 2.923 N/A ASP 7.A N GLY 11.A O no hydrogen 2.868 N/A GLY 11.A N ASP 7.A O no hydrogen 2.898 N/A ILE 13.A N ILE 5.A O no hydrogen 2.893 N/A LEU 15.A N LYS 3.A O no hydrogen 2.895 N/A LEU 18.A N HIS 16.A ND1 no hydrogen 3.225 N/A VAL 20.A N HIS 16.A O no hydrogen 2.942 N/A ARG 21.A N PRO 17.A O no hydrogen 2.900 N/A ILE 22.A N LEU 18.A O no hydrogen 2.942 N/A ILE 23.A N LEU 19.A O no hydrogen 2.892 N/A ASP 24.A N VAL 20.A O no hydrogen 3.237 N/A THR 25.A N ILE 23.A O no hydrogen 2.820 N/A THR 25.A OG1 ILE 22.A O no hydrogen 2.683 N/A PHE 28.A N THR 25.A O no hydrogen 3.205 N/A GLN 29.A N THR 25.A O no hydrogen 2.938 N/A GLN 29.A NE2 ILE 23.A O no hydrogen 3.001 N/A ARG 30.A N PRO 26.A O no hydrogen 2.946 N/A ARG 30.A NE THR 300.A O no hydrogen 3.023 N/A ARG 30.A NH1 HIS 97.A O no hydrogen 3.287 N/A ARG 30.A NH2 LEU 302.A O no hydrogen 2.749 N/A LEU 31.A N PHE 28.A O no hydrogen 3.276 N/A ARG 32.A N GLN 29.A O no hydrogen 3.160 N/A ARG 32.A NE GLN 29.A OE1 no hydrogen 3.185 N/A TYR 33.A N ARG 30.A O no hydrogen 3.325 N/A GLN 36.A N HIS 49.A O no hydrogen 2.997 N/A TYR 41.A N GLY 38.A O no hydrogen 3.435 N/A TYR 42.A N GLY 39.A O no hydrogen 2.925 N/A VAL 43.A N GLY 40.A O no hydrogen 3.138 N/A PHE 44.A N GLY 40.A O no hydrogen 3.040 N/A ALA 47.A N PHE 44.A O no hydrogen 3.274 N/A ARG 51.A N ILE 34.A O no hydrogen 3.383 N/A ARG 51.A NH1 TYR 195.A OH no hydrogen 3.021 N/A GLU 53.A N GLU 53.A OE1 no hydrogen 2.965 N/A HIS 54.A NE2 HIS 93.A NE2 no hydrogen 3.036 N/A HIS 54.A NE2 ASP 94.A OD2 no hydrogen 2.872 N/A SER 55.A N ARG 51.A O no hydrogen 2.918 N/A SER 55.A OG LEU 91.A O no hydrogen 3.377 N/A LEU 56.A N PHE 52.A O no hydrogen 3.026 N/A GLY 57.A N GLU 53.A O no hydrogen 2.889 N/A VAL 58.A N HIS 54.A O no hydrogen 2.919 N/A GLY 59.A N SER 55.A O no hydrogen 2.990 N/A TYR 60.A N LEU 56.A O no hydrogen 2.974 N/A LEU 61.A N GLY 57.A O no hydrogen 2.905 N/A ALA 62.A N VAL 58.A O no hydrogen 2.938 N/A GLY 63.A N GLY 59.A O no hydrogen 2.996 N/A CYS 64.A N TYR 60.A O no hydrogen 2.938 N/A LEU 65.A N LEU 61.A O no hydrogen 2.934 N/A VAL 66.A N ALA 62.A O no hydrogen 2.992 N/A HIS 67.A N GLY 63.A O no hydrogen 2.931 N/A ALA 68.A N CYS 64.A O no hydrogen 2.948 N/A LEU 69.A N LEU 65.A O no hydrogen 2.955 N/A GLY 70.A N VAL 66.A O no hydrogen 2.929 N/A GLU 71.A N HIS 67.A O no hydrogen 2.897 N/A LYS 72.A N ALA 68.A O no hydrogen 2.972 N/A LYS 72.A NZ ILE 215.A O no hydrogen 2.628 N/A LYS 72.A NZ LYS 216.A O no hydrogen 3.306 N/A LYS 72.A NZ ALA 218.A O no hydrogen 2.836 N/A GLN 73.A NE2 GLU 75.A OE2 no hydrogen 3.397 N/A GLN 73.A NE2 VAL 220.A O no hydrogen 3.154 N/A GLU 75.A N GLU 75.A OE1 no hydrogen 2.812 N/A LEU 76.A N GLN 73.A O no hydrogen 3.203 N/A SER 79.A OG ASP 82.A OD2 no hydrogen 3.065 N/A ARG 81.A NH2 ASP 151.A OD1 no hydrogen 2.766 N/A ARG 81.A NH2 ASP 151.A OD2 no hydrogen 3.420 N/A LEU 84.A N GLU 80.A O no hydrogen 2.942 N/A CYS 85.A N ARG 81.A O no hydrogen 2.874 N/A CYS 85.A SG ARG 81.A O no hydrogen 3.357 N/A VAL 86.A N ASP 82.A O no hydrogen 2.921 N/A GLN 87.A N VAL 83.A O no hydrogen 2.920 N/A ILE 88.A N LEU 84.A O no hydrogen 2.905 N/A ALA 89.A N CYS 85.A O no hydrogen 2.906 N/A GLY 90.A N VAL 86.A O no hydrogen 2.923 N/A LEU 91.A N GLN 87.A O no hydrogen 2.912 N/A CYS 92.A N ILE 88.A O no hydrogen 3.102 N/A CYS 92.A SG ILE 88.A O no hydrogen 3.811 N/A HIS 93.A ND1 GLY 90.A O no hydrogen 2.786 N/A HIS 93.A NE2 HIS 54.A NE2 no hydrogen 3.036 N/A GLY 96.A N SER 124.A OG no hydrogen 2.806 N/A PHE 100.A N ASP 304.A OD1 no hydrogen 3.025 N/A SER 101.A N GLY 98.A O no hydrogen 3.015 N/A SER 101.A OG LYS 35.A O no hydrogen 2.261 N/A MET 103.A N PHE 100.A O no hydrogen 3.458 N/A PHE 104.A N SER 101.A O no hydrogen 2.937 N/A GLY 106.A N HIS 102.A O no hydrogen 3.110 N/A ARG 107.A N MET 103.A O no hydrogen 2.819 N/A ARG 107.A N PHE 104.A O no hydrogen 3.007 N/A ARG 107.A NH1 VAL 380.A O no hydrogen 2.755 N/A ARG 107.A NH2 VAL 380.A O no hydrogen 2.904 N/A PHE 108.A N PHE 104.A O no hydrogen 2.773 N/A ILE 109.A N PHE 104.A O no hydrogen 3.473 N/A ALA 112.A N PHE 108.A O no hydrogen 2.979 N/A ALA 112.A N ILE 109.A O no hydrogen 3.058 N/A ARG 113.A N ILE 109.A O no hydrogen 2.778 N/A ARG 113.A NH1 SER 290.A O no hydrogen 2.968 N/A GLU 115.A N GLU 115.A OE1 no hydrogen 2.681 N/A VAL 116.A N ARG 113.A O no hydrogen 3.246 N/A GLY 123.A N THR 119.A O no hydrogen 3.377 N/A SER 124.A N HIS 120.A O no hydrogen 2.880 N/A SER 124.A OG HIS 93.A O no hydrogen 3.274 N/A SER 124.A OG HIS 120.A O no hydrogen 2.824 N/A VAL 125.A N GLU 121.A O no hydrogen 2.940 N/A MET 126.A N GLN 122.A O no hydrogen 2.934 N/A MET 127.A N GLY 123.A O no hydrogen 2.856 N/A PHE 128.A N SER 124.A O no hydrogen 2.885 N/A GLU 129.A N VAL 125.A O no hydrogen 2.986 N/A HIS 130.A N MET 126.A O no hydrogen 2.914 N/A LEU 131.A N MET 127.A O no hydrogen 2.850 N/A ILE 132.A N PHE 128.A O no hydrogen 2.951 N/A ASN 133.A N GLU 129.A O no hydrogen 2.947 N/A SER 134.A N HIS 130.A O no hydrogen 2.869 N/A SER 134.A N LEU 131.A O no hydrogen 3.277 N/A ASN 135.A N LEU 131.A O no hydrogen 2.943 N/A ASN 135.A ND2 GLN 27.A OE1 no hydrogen 2.960 N/A ASN 135.A ND2 LEU 131.A O no hydrogen 3.445 N/A ILE 137.A N ILE 132.A O no hydrogen 3.522 N/A MET 141.A N ILE 137.A O no hydrogen 2.913 N/A GLU 142.A N LYS 138.A O no hydrogen 2.932 N/A GLN 143.A N PRO 139.A O no hydrogen 2.899 N/A TYR 144.A N MET 141.A O no hydrogen 3.107 N/A LEU 146.A N MET 141.A O no hydrogen 3.220 N/A GLU 149.A N GLU 149.A OE1 no hydrogen 2.707 N/A ASP 151.A N ILE 147.A O no hydrogen 3.195 N/A ILE 152.A N PRO 148.A O no hydrogen 2.889 N/A CYS 153.A N GLU 149.A O no hydrogen 2.957 N/A CYS 153.A SG GLU 157.A OE2 no hydrogen 3.690 N/A PHE 154.A N GLU 150.A O no hydrogen 2.881 N/A ILE 155.A N ASP 151.A O no hydrogen 2.910 N/A LYS 156.A N ILE 152.A O no hydrogen 2.928 N/A GLU 157.A N CYS 153.A O no hydrogen 2.890 N/A GLN 158.A N PHE 154.A O no hydrogen 2.927 N/A ILE 159.A N ILE 155.A O no hydrogen 2.966 N/A ILE 159.A N LYS 156.A O no hydrogen 3.045 N/A VAL 160.A N LYS 156.A O no hydrogen 2.880 N/A TRP 165.A NE1 ARG 170.A O no hydrogen 3.203 N/A LYS 168.A N GLU 157.A OE1 no hydrogen 3.115 N/A LYS 168.A N GLU 157.A OE2 no hydrogen 3.025 N/A GLY 169.A N GLU 157.A OE1 no hydrogen 2.873 N/A ARG 170.A NE ASP 82.A OD1 no hydrogen 3.151 N/A ARG 170.A NH1 GLY 169.A O no hydrogen 2.731 N/A ARG 170.A NH2 ASP 82.A OD1 no hydrogen 3.084 N/A ARG 170.A NH2 ASP 151.A OD1 no hydrogen 3.346 N/A LYS 174.A N PRO 171.A O no hydrogen 3.263 N/A LYS 174.A NZ GLN 77.A O no hydrogen 2.590 N/A LYS 174.A NZ ASP 82.A OD2 no hydrogen 2.977 N/A ASN 183.A N ASP 189.A OD2 no hydrogen 3.353 N/A LYS 184.A NZ SER 182.A OG no hydrogen 2.818 N/A ASN 186.A ND2 HIS 389.A O no hydrogen 3.434 N/A ILE 188.A N ASN 186.A OD1 no hydrogen 3.031 N/A VAL 190.A N ILE 180.A O no hydrogen 3.507 N/A LYS 192.A N ASP 189.A O no hydrogen 3.255 N/A TRP 193.A N ASP 189.A O no hydrogen 3.424 N/A ASP 194.A N VAL 190.A O no hydrogen 2.958 N/A TYR 195.A N ASP 191.A O no hydrogen 3.407 N/A PHE 196.A N LYS 192.A O no hydrogen 2.922 N/A ALA 197.A N TRP 193.A O no hydrogen 2.957 N/A ARG 198.A N ASP 194.A O no hydrogen 2.926 N/A ARG 198.A NE ASP 194.A OD1 no hydrogen 3.140 N/A ARG 198.A NH1 ASP 7.A OD1 no hydrogen 3.336 N/A ARG 198.A NH2 ASP 7.A OD2 no hydrogen 3.078 N/A ASP 199.A N TYR 195.A O no hydrogen 2.912 N/A CYS 200.A N PHE 196.A O no hydrogen 2.953 N/A HIS 201.A N ALA 197.A O no hydrogen 2.928 N/A HIS 202.A N ARG 198.A O no hydrogen 2.941 N/A LEU 203.A N ASP 199.A O no hydrogen 2.888 N/A GLY 204.A N CYS 200.A O no hydrogen 3.228 N/A ASN 207.A N ASN 207.A OD1 no hydrogen 2.642 N/A ASN 208.A ND2 ASP 241.A OD1 no hydrogen 3.517 N/A ILE 215.A N TYR 211.A O no hydrogen 2.907 N/A LYS 216.A N LYS 212.A O no hydrogen 2.908 N/A PHE 217.A N ARG 213.A O no hydrogen 2.939 N/A ALA 218.A N PHE 214.A O no hydrogen 2.728 N/A ARG 219.A N CYS 230.A O no hydrogen 2.931 N/A ARG 219.A NH2 ASN 399.A OD1 no hydrogen 2.805 N/A CYS 221.A N ARG 228.A O no hydrogen 2.921 N/A VAL 223.A N GLU 226.A O no hydrogen 2.890 N/A GLU 226.A N VAL 223.A O no hydrogen 2.880 N/A ARG 228.A N CYS 221.A O no hydrogen 3.141 N/A CYS 230.A N ARG 219.A O no hydrogen 2.859 N/A CYS 230.A SG CYS 221.A O no hydrogen 3.437 N/A CYS 230.A SG ARG 228.A O no hydrogen 3.022 N/A CYS 230.A SG SER 391.A OG no hydrogen 3.503 N/A ASP 233.A N TYR 393.A O no hydrogen 3.111 N/A GLU 235.A N ARG 232.A O no hydrogen 3.041 N/A ASN 238.A ND2 GLU 235.A OE1 no hydrogen 3.115 N/A LEU 239.A N GLU 235.A O no hydrogen 2.946 N/A TYR 240.A N VAL 236.A O no hydrogen 2.933 N/A ASP 241.A N GLY 237.A O no hydrogen 2.887 N/A MET 242.A N ASN 238.A O no hydrogen 2.883 N/A PHE 243.A N LEU 239.A O no hydrogen 2.968 N/A HIS 244.A N TYR 240.A O no hydrogen 2.894 N/A THR 245.A N ASP 241.A O no hydrogen 2.885 N/A THR 245.A OG1 ASP 241.A O no hydrogen 3.328 N/A THR 245.A OG1 ASP 241.A OD1 no hydrogen 3.523 N/A ARG 246.A N MET 242.A O no hydrogen 2.958 N/A ASN 247.A N PHE 243.A O no hydrogen 2.930 N/A SER 248.A N HIS 244.A O no hydrogen 2.877 N/A LEU 249.A N THR 245.A O no hydrogen 2.932 N/A HIS 250.A N ARG 246.A O no hydrogen 2.963 N/A ARG 251.A N ASN 247.A O no hydrogen 2.910 N/A ARG 252.A N SER 248.A O no hydrogen 2.930 N/A ARG 252.A N LEU 249.A O no hydrogen 3.329 N/A ALA 253.A N LEU 249.A O no hydrogen 2.910 N/A TYR 254.A N LEU 249.A O no hydrogen 3.468 N/A TYR 254.A OH ASP 199.A OD2 no hydrogen 1.951 N/A LYS 257.A NZ TYR 336.A OH no hydrogen 3.526 N/A VAL 258.A N HIS 256.A ND1 no hydrogen 3.259 N/A ILE 262.A N VAL 258.A O no hydrogen 2.934 N/A ASP 263.A N GLY 259.A O no hydrogen 2.918 N/A THR 264.A N ASN 260.A O no hydrogen 2.917 N/A THR 264.A OG1 ASN 260.A O no hydrogen 3.357 N/A THR 264.A OG1 ILE 261.A O no hydrogen 2.374 N/A MET 265.A N ILE 261.A O no hydrogen 2.939 N/A ILE 266.A N ILE 262.A O no hydrogen 2.918 N/A THR 267.A N ASP 263.A O no hydrogen 2.913 N/A THR 267.A OG1 ASP 263.A O no hydrogen 2.951 N/A ASP 268.A N THR 264.A O no hydrogen 2.912 N/A ALA 269.A N MET 265.A O no hydrogen 2.950 N/A PHE 270.A N ILE 266.A O no hydrogen 2.902 N/A LEU 271.A N THR 267.A O no hydrogen 2.881 N/A LYS 272.A N ASP 268.A O no hydrogen 2.967 N/A ALA 273.A N ALA 269.A O no hydrogen 2.889 N/A ASP 274.A N PHE 270.A O no hydrogen 2.933 N/A ILE 279.A N TYR 287.A O no hydrogen 3.180 N/A GLY 281.A N LYS 285.A O no hydrogen 2.732 N/A ALA 282.A N ASP 295.A OD2 no hydrogen 2.885 N/A GLY 284.A N GLY 281.A O no hydrogen 3.296 N/A LYS 286.A NZ THR 280.A OG1 no hydrogen 2.955 N/A LYS 286.A NZ GLY 284.A O no hydrogen 3.417 N/A TYR 287.A N ILE 279.A O no hydrogen 2.654 N/A ARG 288.A N THR 291.A OG1 no hydrogen 3.020 N/A SER 290.A N ASP 274.A OD2 no hydrogen 3.332 N/A SER 290.A OG ASP 274.A OD2 no hydrogen 3.542 N/A ASP 294.A N THR 291.A O no hydrogen 3.197 N/A ASP 295.A N ALA 292.A O no hydrogen 3.184 N/A ALA 298.A N ASP 295.A OD2 no hydrogen 3.391 N/A TYR 299.A N ASP 295.A O no hydrogen 2.989 N/A TYR 299.A OH GLY 96.A O no hydrogen 2.879 N/A THR 300.A N MET 296.A O no hydrogen 2.907 N/A THR 300.A OG1 MET 296.A O no hydrogen 2.677 N/A LYS 301.A N ALA 298.A O no hydrogen 3.311 N/A LEU 302.A N TYR 299.A O no hydrogen 3.320 N/A ASP 304.A N TYR 33.A O no hydrogen 3.416 N/A ILE 306.A N THR 303.A O no hydrogen 3.413 N/A GLU 309.A N ASN 305.A O no hydrogen 2.838 N/A ILE 310.A N ILE 306.A O no hydrogen 2.987 N/A ILE 310.A N PHE 307.A O no hydrogen 2.939 N/A LEU 311.A N PHE 307.A O no hydrogen 3.043 N/A TYR 312.A N LEU 308.A O no hydrogen 3.195 N/A SER 313.A N ILE 310.A O no hydrogen 3.309 N/A SER 313.A OG ILE 310.A O no hydrogen 2.514 N/A LYS 317.A N ASP 315.A OD1 no hydrogen 2.954 N/A LEU 318.A N ASP 315.A O no hydrogen 3.135 N/A LYS 319.A N PRO 316.A O no hydrogen 2.911 N/A ARG 322.A N LEU 318.A O no hydrogen 2.926 N/A ARG 322.A NH1 SER 313.A OG no hydrogen 2.831 N/A ARG 322.A NH1 ASP 315.A O no hydrogen 3.240 N/A GLU 323.A N LYS 319.A O no hydrogen 2.798 N/A ILE 324.A N ASP 320.A O no hydrogen 3.258 N/A LEU 325.A N ALA 321.A O no hydrogen 3.223 N/A LYS 326.A N ARG 322.A O no hydrogen 3.016 N/A GLN 327.A N GLU 323.A O no hydrogen 3.177 N/A GLN 327.A N ILE 324.A O no hydrogen 2.941 N/A GLN 327.A NE2 GLU 323.A O no hydrogen 3.675 N/A GLU 329.A N LEU 325.A O no hydrogen 3.360 N/A GLU 329.A N LYS 326.A O no hydrogen 2.920 N/A TYR 330.A N GLN 327.A O no hydrogen 2.929 N/A ARG 331.A N ILE 328.A O no hydrogen 3.468 N/A ARG 331.A NH2 TYR 42.A O no hydrogen 2.414 N/A ASN 332.A N GLN 327.A O no hydrogen 3.116 N/A ASN 332.A ND2 GLN 327.A OE1 no hydrogen 3.078 N/A LYS 335.A NZ LEU 333.A O no hydrogen 3.275 N/A VAL 337.A N VAL 409.A O no hydrogen 3.181 N/A GLY 338.A N VAL 409.A O no hydrogen 3.392 N/A THR 340.A N ILE 407.A O no hydrogen 3.170 N/A ASP 352.A N LYS 349.A O no hydrogen 3.099 N/A TYR 353.A N ARG 350.A O no hydrogen 2.923 N/A SER 355.A N ASP 352.A O no hydrogen 2.932 N/A SER 355.A OG ASP 352.A O no hydrogen 2.606 N/A LYS 358.A N SER 355.A O no hydrogen 3.101 N/A GLU 359.A N LEU 356.A O no hydrogen 3.157 N/A VAL 360.A N LEU 356.A O no hydrogen 3.383 N/A SER 362.A N LYS 358.A O no hydrogen 3.084 N/A SER 362.A OG GLU 359.A O no hydrogen 2.580 N/A ALA 363.A N GLU 359.A O no hydrogen 3.126 N/A LYS 372.A NZ TYR 425.A OH no hydrogen 2.903 N/A ASP 377.A N LYS 374.A O no hydrogen 3.313 N/A ILE 379.A N TYR 410.A O no hydrogen 2.912 N/A ASP 381.A N ARG 408.A O no hydrogen 2.870 N/A MET 385.A N GLU 404.A O no hydrogen 2.948 N/A TYR 393.A N ALA 231.A O no hydrogen 2.964 N/A TYR 393.A OH PHE 217.A O no hydrogen 2.828 N/A CYS 394.A SG ASP 233.A OD2 no hydrogen 3.771 N/A CYS 394.A SG THR 396.A OG1 no hydrogen 3.380 N/A ALA 397.A N CYS 394.A O no hydrogen 3.039 N/A ARG 400.A N ALA 397.A O no hydrogen 3.304 N/A ILE 402.A N PHE 392.A O no hydrogen 2.460 N/A ALA 403.A N MET 385.A O no hydrogen 2.599 N/A GLU 404.A N MET 385.A O no hydrogen 3.023 N/A GLN 405.A NE2 ILE 348.A O no hydrogen 3.683 N/A ARG 408.A N ASP 381.A O no hydrogen 2.905 N/A ARG 408.A NH2 GLN 255.A O no hydrogen 3.349 N/A VAL 409.A N GLY 338.A O no hydrogen 2.925 N/A TYR 410.A N ILE 379.A O no hydrogen 2.897 N/A CYS 411.A SG ASP 377.A O no hydrogen 3.726 N/A CYS 411.A SG LYS 413.A O no hydrogen 3.300 N/A LYS 412.A N ASP 377.A O no hydrogen 2.685 N/A LYS 412.A NZ ASP 268.A OD2 no hydrogen 3.024 N/A LEU 419.A N ASP 415.A O no hydrogen 2.714 N/A TYR 420.A N ARG 416.A O no hydrogen 2.906 N/A ALA 421.A N LYS 417.A O no hydrogen 2.932 N/A ALA 422.A N SER 418.A O no hydrogen 2.892 N/A ARG 423.A N LEU 419.A O no hydrogen 2.906 N/A GLN 424.A N TYR 420.A O no hydrogen 3.250 N/A GLN 424.A N ALA 421.A O no hydrogen 3.013 N/A TYR 425.A N ALA 421.A O no hydrogen 2.972 N/A PHE 426.A N ALA 422.A O no hydrogen 3.230 N/A GLN 428.A N GLN 424.A O no hydrogen 3.332 N/A TRP 429.A N TYR 425.A O no hydrogen 2.948 N/A CYS 430.A N PHE 426.A O no hydrogen 2.902 N/A CYS 430.A SG PHE 426.A O no hydrogen 3.623 N/A CYS 430.A SG VAL 427.A O no hydrogen 2.920 N/A ALA 431.A N VAL 427.A O no hydrogen 2.899 N/A ASP 432.A N GLN 428.A O no hydrogen 2.881 N/A ARG 433.A N TRP 429.A O no hydrogen 3.415 N/A ASN 434.A N ALA 431.A O no hydrogen 3.465 N/A PHE 435.A N CYS 430.A O no hydrogen 2.613 N/A