Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8r5j_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): VAL 4.A N GLN 299.A OE1 no hydrogen 3.036 N/A SER 7.A OG THR 130.A OG1 no hydrogen 2.693 N/A HIS 8.A N SER 116.A OG no hydrogen 2.901 N/A SER 10.A OG GLU 14.A OE2 no hydrogen 2.579 N/A VAL 13.A N SER 10.A O no hydrogen 3.076 N/A GLU 14.A N SER 10.A O no hydrogen 2.949 N/A ALA 15.A N GLY 11.A O no hydrogen 3.368 N/A CYS 16.A N VAL 13.A O no hydrogen 2.907 N/A CYS 16.A SG ASP 12.A O no hydrogen 3.476 N/A MET 17.A N GLU 14.A O no hydrogen 3.174 N/A VAL 18.A N GLY 29.A O no hydrogen 3.073 N/A GLN 19.A N GLN 69.A O no hydrogen 2.829 N/A GLN 19.A NE2 ASN 122.A OD1 no hydrogen 3.612 N/A VAL 20.A N LEU 27.A O no hydrogen 2.915 N/A THR 21.A N SER 67.A O no hydrogen 2.874 N/A THR 21.A OG1 THR 26.A OG1 no hydrogen 2.786 N/A CYS 22.A N MET 25.A O no hydrogen 2.964 N/A CYS 22.A SG SER 65.A O no hydrogen 3.757 N/A MET 25.A N CYS 22.A O no hydrogen 3.109 N/A THR 26.A OG1 THR 21.A OG1 no hydrogen 2.786 N/A LEU 27.A N VAL 20.A O no hydrogen 3.057 N/A ASN 28.A N CYS 148.A O no hydrogen 3.018 N/A ASN 28.A ND2 CYS 120.A O no hydrogen 2.917 N/A ASN 28.A ND2 GLY 146.A O no hydrogen 3.042 N/A ASN 28.A ND2 CYS 148.A O no hydrogen 2.981 N/A GLY 29.A N VAL 18.A O no hydrogen 2.888 N/A LEU 30.A N TRP 37.A O no hydrogen 2.822 N/A TRP 31.A N CYS 16.A O no hydrogen 2.826 N/A TRP 31.A NE1 VAL 96.A O no hydrogen 3.232 N/A LEU 32.A N THR 35.A O no hydrogen 2.895 N/A ASP 33.A N THR 101.A OG1 no hydrogen 2.945 N/A ASN 34.A ND2 VAL 94.A O no hydrogen 3.432 N/A THR 35.A N LEU 32.A O no hydrogen 2.926 N/A VAL 36.A N LEU 92.A O no hydrogen 2.845 N/A TRP 37.A N LEU 30.A O no hydrogen 2.891 N/A CYS 38.A N LEU 90.A O no hydrogen 3.236 N/A CYS 38.A SG PRO 39.A O no hydrogen 3.739 N/A ARG 40.A N THR 88.A O no hydrogen 3.162 N/A ARG 40.A NE ASP 190.A OD2 no hydrogen 2.786 N/A ARG 40.A NH2 ASP 190.A OD1 no hydrogen 2.900 N/A VAL 42.A N PRO 39.A O no hydrogen 3.374 N/A MET 43.A N ARG 40.A O no hydrogen 3.226 N/A CYS 44.A N HIS 41.A O no hydrogen 3.231 N/A CYS 44.A SG PRO 45.A O no hydrogen 3.435 N/A GLN 48.A N PRO 45.A O no hydrogen 2.981 N/A LEU 49.A N ALA 46.A O no hydrogen 3.368 N/A TYR 54.A OH ASP 190.A O no hydrogen 2.770 N/A ALA 56.A N ASN 53.A OD1 no hydrogen 3.406 N/A LEU 57.A N ASN 53.A O no hydrogen 2.998 N/A LEU 58.A N TYR 54.A O no hydrogen 2.930 N/A ILE 59.A N ASP 55.A O no hydrogen 3.341 N/A SER 60.A N ALA 56.A O no hydrogen 3.232 N/A SER 60.A OG LEU 57.A O no hydrogen 2.700 N/A MET 61.A N LEU 58.A O no hydrogen 3.095 N/A THR 62.A N SER 65.A OG no hydrogen 2.997 N/A THR 62.A OG1 HIS 64.A ND1.B no hydrogen 3.377 N/A SER 65.A N THR 62.A O no hydrogen 2.917 N/A SER 65.A OG THR 62.A O no hydrogen 3.130 N/A PHE 66.A N ASN 63.A O no hydrogen 3.353 N/A SER 67.A N THR 21.A O no hydrogen 2.992 N/A GLN 69.A N GLN 19.A O no hydrogen 2.958 N/A LYS 70.A N ALA 76.A O no hydrogen 2.866 N/A LYS 70.A NZ ALA 15.A O no hydrogen 3.395 N/A LYS 70.A NZ ILE 72.A O no hydrogen 3.455 N/A HIS 71.A NE2 GLN 19.A OE1 no hydrogen 2.947 N/A ALA 76.A N LYS 70.A O no hydrogen 3.276 N/A ASN 77.A ND2 VAL 68.A O no hydrogen 2.896 N/A LEU 78.A N VAL 68.A O no hydrogen 2.974 N/A VAL 81.A N THR 93.A O no hydrogen 2.847 N/A ALA 84.A N LYS 91.A O no hydrogen 3.040 N/A GLN 86.A N LEU 89.A O no hydrogen 2.853 N/A THR 88.A N GLY 182.A O no hydrogen 2.861 N/A THR 88.A OG1 GLY 182.A O no hydrogen 2.855 N/A LEU 89.A N GLN 86.A O no hydrogen 3.044 N/A LEU 90.A N CYS 38.A O no hydrogen 2.838 N/A LYS 91.A N ALA 84.A O no hydrogen 2.839 N/A LEU 92.A N VAL 36.A O no hydrogen 2.876 N/A THR 93.A N GLY 82.A O no hydrogen 2.854 N/A VAL 94.A N ASN 34.A O no hydrogen 2.895 N/A ASP 95.A N ARG 79.A O no hydrogen 3.062 N/A ASN 98.A N ASP 33.A O no hydrogen 2.981 N/A ASN 98.A ND2 ALA 15.A O no hydrogen 3.362 N/A ASN 98.A ND2 TRP 31.A O no hydrogen 2.836 N/A SER 100.A N ASN 98.A OD1 no hydrogen 2.941 N/A THR 101.A N ASN 98.A O no hydrogen 3.342 N/A THR 101.A OG1 ASP 33.A OD1 no hydrogen 3.453 N/A THR 101.A OG1 ASN 98.A O no hydrogen 2.855 N/A THR 105.A N ILE 160.A O no hydrogen 2.963 N/A THR 105.A OG1 ASN 161.A OD1 no hydrogen 2.464 N/A THR 107.A N PHE 162.A O no hydrogen 3.165 N/A VAL 109.A N TYR 185.A OH no hydrogen 3.020 N/A GLY 112.A N MET 133.A O no hydrogen 2.820 N/A ALA 113.A N LYS 110.A O no hydrogen 3.132 N/A PHE 115.A N VAL 131.A O no hydrogen 2.966 N/A SER 116.A N TYR 153.A O no hydrogen 2.912 N/A VAL 117.A N PHE 129.A O no hydrogen 2.771 N/A LEU 118.A N VAL 151.A O no hydrogen 2.918 N/A ALA 119.A N GLY 127.A O no hydrogen 2.788 N/A CYS 120.A N SER 150.A OG no hydrogen 2.973 N/A CYS 120.A SG LEU 118.A O no hydrogen 3.647 N/A TYR 121.A N ARG 124.A O no hydrogen 2.981 N/A GLY 123.A N ASN 28.A OD1 no hydrogen 2.849 N/A ARG 124.A N TYR 121.A O no hydrogen 2.942 N/A THR 126.A N ALA 119.A O no hydrogen 2.872 N/A THR 126.A OG1 ALA 119.A O no hydrogen 3.309 N/A GLY 127.A N ALA 119.A O no hydrogen 3.407 N/A THR 128.A OG1 VAL 117.A O no hydrogen 2.858 N/A PHE 129.A N VAL 117.A O no hydrogen 3.146 N/A THR 130.A OG1 MET 6.A O no hydrogen 2.802 N/A THR 130.A OG1 SER 7.A OG no hydrogen 2.693 N/A VAL 131.A N PHE 115.A O no hydrogen 2.968 N/A MET 133.A N ALA 113.A O no hydrogen 2.986 N/A ARG 134.A N THR 138.A O no hydrogen 2.878 N/A ARG 134.A NE ASP 200.A OD1 no hydrogen 3.218 N/A ARG 134.A NE ASP 200.A OD2 no hydrogen 3.326 N/A ARG 134.A NH1 ASP 289.A OD1 no hydrogen 3.096 N/A ARG 134.A NH1 ASP 289.A OD2 no hydrogen 3.473 N/A ARG 134.A NH1 GLU 290.A OE2 no hydrogen 2.972 N/A ARG 134.A NH2 ASP 289.A OD2 no hydrogen 2.790 N/A ASN 136.A ND2 LEU 198.A O no hydrogen 3.000 N/A TYR 137.A N ARG 134.A O no hydrogen 2.826 N/A THR 138.A OG1 ASN 136.A OD1 no hydrogen 2.739 N/A ILE 139.A N HIS 175.A O no hydrogen 2.909 N/A LYS 140.A NZ ASP 200.A OD2 no hydrogen 3.164 N/A LEU 144.A N TYR 121.A OH no hydrogen 2.919 N/A SER 147.A N LEU 144.A O no hydrogen 3.134 N/A SER 147.A OG LEU 144.A O no hydrogen 2.737 N/A CYS 148.A SG HIS 41.A NE2 no hydrogen 3.823 N/A CYS 148.A SG GLN 167.A O no hydrogen 3.243 N/A GLY 149.A N HIS 166.A O no hydrogen 2.881 N/A SER 150.A N SER 147.A O no hydrogen 3.010 N/A SER 150.A OG SER 147.A O no hydrogen 2.648 N/A GLY 152.A N TYR 164.A O no hydrogen 2.808 N/A TYR 153.A N SER 116.A O no hydrogen 2.876 N/A THR 154.A N ASN 161.A O no hydrogen 3.056 N/A LYS 155.A N HIS 8.A NE2 no hydrogen 3.267 N/A GLU 156.A N VAL 159.A O no hydrogen 2.960 N/A VAL 159.A N GLU 156.A O no hydrogen 3.067 N/A ILE 160.A N ALA 103.A O no hydrogen 2.894 N/A ASN 161.A N THR 154.A O no hydrogen 2.839 N/A ASN 161.A ND2 THR 154.A OG1 no hydrogen 3.343 N/A PHE 162.A N THR 105.A O no hydrogen 2.862 N/A CYS 163.A N GLY 152.A O no hydrogen 3.012 N/A TYR 164.A N GLY 152.A O no hydrogen 3.269 N/A TYR 164.A OH HIS 166.A ND1 no hydrogen 2.756 N/A MET 165.A N SER 178.A O no hydrogen 2.905 N/A HIS 166.A N SER 150.A O no hydrogen 2.840 N/A HIS 166.A ND1 TYR 164.A OH no hydrogen 2.756 N/A GLN 167.A N THR 176.A O no hydrogen 3.163 N/A GLN 167.A NE2 THR 88.A O no hydrogen 2.993 N/A GLN 167.A NE2 SER 178.A OG no hydrogen 3.429 N/A MET 168.A N THR 176.A O no hydrogen 3.110 N/A LEU 170.A N THR 174.A O no hydrogen 3.050 N/A THR 174.A N ALA 171.A O no hydrogen 2.899 N/A THR 174.A OG1 ASN 172.A O no hydrogen 3.462 N/A HIS 175.A N ILE 139.A O no hydrogen 2.950 N/A THR 176.A N MET 168.A O no hydrogen 3.037 N/A THR 176.A OG1 TYR 137.A O no hydrogen 3.172 N/A THR 176.A OG1 TYR 185.A O no hydrogen 3.444 N/A SER 178.A N MET 165.A O no hydrogen 3.042 N/A ALA 179.A N THR 183.A O no hydrogen 2.891 N/A GLY 182.A N ALA 179.A O no hydrogen 2.937 N/A THR 183.A N ASP 181.A OD1 no hydrogen 3.034 N/A THR 183.A OG1.B ASP 181.A OD1 no hydrogen 2.835 N/A THR 183.A OG1.B ASP 181.A OD2 no hydrogen 3.504 N/A TYR 185.A N GLY 177.A O no hydrogen 2.894 N/A TYR 185.A OH CYS 163.A O no hydrogen 2.549 N/A ALA 187.A N MET 184.A O no hydrogen 3.147 N/A MET 189.A N GLN 195.A OE1 no hydrogen 2.868 N/A GLN 192.A N LEU 49.A O no hydrogen 2.895 N/A VAL 193.A N LYS 191.A O no hydrogen 2.953 N/A GLN 195.A NE2 MET 189.A O no hydrogen 3.045 N/A GLN 195.A NE2 LYS 191.A O no hydrogen 3.699 N/A GLN 197.A N GLN 197.A OE1 no hydrogen 2.987 N/A LYS 201.A N ASP 200.A OD1 no hydrogen 3.112 N/A TYR 202.A N GLN 241.A O no hydrogen 2.970 N/A CYS 203.A N ASP 289.A OD2 no hydrogen 2.900 N/A CYS 203.A SG ASP 289.A OD2 no hydrogen 3.861 N/A SER 204.A N THR 243.A OG1 no hydrogen 3.146 N/A SER 204.A OG THR 243.A O no hydrogen 2.674 N/A ASN 206.A ND2 GLY 112.A O no hydrogen 2.952 N/A ASN 206.A ND2 ASP 289.A O no hydrogen 2.937 N/A VAL 207.A N CYS 203.A O no hydrogen 3.072 N/A VAL 208.A N SER 204.A O no hydrogen 3.083 N/A ALA 209.A N VAL 205.A O no hydrogen 3.084 N/A TRP 210.A N ASN 206.A O no hydrogen 2.980 N/A LEU 211.A N VAL 207.A O no hydrogen 2.942 N/A TYR 212.A N VAL 208.A O no hydrogen 2.941 N/A TYR 212.A OH VAL 260.A O no hydrogen 2.804 N/A ALA 213.A N ALA 209.A O no hydrogen 3.032 N/A ALA 214.A N TRP 210.A O no hydrogen 2.958 N/A ILE 215.A N LEU 211.A O no hydrogen 3.106 N/A LEU 216.A N TYR 212.A O no hydrogen 3.003 N/A ASN 217.A N ALA 213.A O no hydrogen 3.173 N/A ASN 217.A N ALA 214.A O no hydrogen 3.224 N/A ASN 217.A ND2 ALA 213.A O no hydrogen 2.860 N/A GLY 218.A N ILE 215.A O no hydrogen 3.124 N/A CYS 219.A N ALA 214.A O no hydrogen 2.822 N/A CYS 219.A SG GLN 280.A O no hydrogen 3.927 N/A TRP 221.A NE1 GLN 280.A O no hydrogen 3.074 N/A VAL 223.A N ALA 220.A O no hydrogen 3.111 N/A THR 228.A N GLU 263.A O no hydrogen 2.926 N/A THR 228.A OG1 GLN 270.A OE1 no hydrogen 2.756 N/A SER 229.A OG SER 232.A OG no hydrogen 2.671 N/A SER 232.A N SER 229.A OG no hydrogen 3.017 N/A SER 232.A OG SER 229.A OG no hydrogen 2.671 N/A PHE 233.A N SER 229.A O no hydrogen 2.885 N/A ASN 234.A N VAL 230.A O no hydrogen 2.890 N/A ASN 234.A ND2 PHE 245.A O no hydrogen 3.325 N/A GLU 235.A N VAL 231.A O no hydrogen 3.280 N/A TRP 236.A N SER 232.A O no hydrogen 3.088 N/A ALA 237.A N PHE 233.A O no hydrogen 2.751 N/A LEU 238.A N ASN 234.A O no hydrogen 3.312 N/A ALA 239.A N TRP 236.A O no hydrogen 3.158 N/A ASN 240.A N ALA 237.A O no hydrogen 3.079 N/A ASN 240.A ND2 TRP 236.A O no hydrogen 2.786 N/A GLN 241.A NE2 THR 199.A OG1 no hydrogen 3.348 N/A PHE 242.A N ALA 237.A O no hydrogen 3.242 N/A THR 243.A N TYR 202.A O no hydrogen 2.961 N/A THR 243.A OG1 TYR 202.A O no hydrogen 3.534 N/A PHE 245.A N ASN 234.A OD1 no hydrogen 2.842 N/A VAL 251.A N THR 248.A OG1 no hydrogen 3.347 N/A ASP 252.A N THR 248.A O no hydrogen 3.064 N/A MET 253.A N GLN 249.A O no hydrogen 2.979 N/A LEU 254.A N SER 250.A O no hydrogen 3.355 N/A ALA 255.A N VAL 251.A O no hydrogen 3.070 N/A VAL 256.A N ASP 252.A O no hydrogen 2.985 N/A LYS 257.A N MET 253.A O no hydrogen 3.035 N/A THR 258.A N LEU 254.A O no hydrogen 3.048 N/A THR 258.A OG1 LEU 254.A O no hydrogen 2.869 N/A THR 258.A OG1 ALA 255.A O no hydrogen 3.565 N/A GLY 259.A N ALA 255.A O no hydrogen 2.911 N/A VAL 260.A N THR 258.A OG1 no hydrogen 3.180 N/A GLU 263.A N GLU 263.A OE1 no hydrogen 2.796 N/A GLN 264.A N ALA 261.A O no hydrogen 3.049 N/A LEU 265.A N ALA 261.A O no hydrogen 3.445 N/A LEU 266.A N ILE 262.A O no hydrogen 2.932 N/A TYR 267.A N GLU 263.A O no hydrogen 3.231 N/A ALA 268.A N GLN 264.A O no hydrogen 3.062 N/A ILE 269.A N LEU 265.A O no hydrogen 2.913 N/A GLN 270.A N LEU 266.A O no hydrogen 3.267 N/A GLN 271.A N TYR 267.A O no hydrogen 3.138 N/A LEU 272.A N ALA 268.A O no hydrogen 2.806 N/A TYR 273.A N ILE 269.A O no hydrogen 2.910 N/A THR 274.A N GLN 271.A O no hydrogen 3.148 N/A THR 274.A OG1 GLN 271.A O no hydrogen 2.779 N/A GLY 275.A N LEU 272.A O no hydrogen 3.150 N/A LYS 279.A N PHE 276.A O no hydrogen 2.866 N/A ILE 281.A N SER 284.A O no hydrogen 2.874 N/A SER 284.A N ILE 281.A O no hydrogen 3.027 N/A GLU 290.A N GLU 288.A OE2 no hydrogen 3.292 N/A THR 292.A OG1 GLU 294.A OE1 no hydrogen 3.161 N/A GLU 294.A N GLU 294.A OE1 no hydrogen 2.842 N/A ASP 295.A N THR 292.A OG1 no hydrogen 3.177 N/A VAL 296.A N THR 292.A O no hydrogen 3.057 N/A ASN 297.A N PRO 293.A O no hydrogen 2.922 N/A MET 298.A N GLU 294.A O no hydrogen 2.916 N/A GLN 299.A N ASP 295.A O no hydrogen 2.960 N/A GLN 299.A NE2 VAL 4.A O no hydrogen 2.877 N/A GLN 299.A NE2 ASP 295.A OD1 no hydrogen 3.146 N/A ILE 300.A N VAL 296.A O no hydrogen 2.870 N/A MET 301.A N ASN 297.A O no hydrogen 3.106 N/A VAL 303.A N ASN 297.A O no hydrogen 3.407 N/A