Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8r8q_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): HIS 5.A N SER 1.A OG no hydrogen 3.024 N/A ARG 6.A N LEU 3.A O no hydrogen 3.240 N/A LEU 7.A N ALA 4.A O no hydrogen 3.280 N/A LEU 10.A N ARG 6.A O no hydrogen 2.920 N/A SER 11.A N LEU 7.A O no hydrogen 2.915 N/A LEU 12.A N VAL 8.A O no hydrogen 2.885 N/A MET 13.A N VAL 9.A O no hydrogen 2.889 N/A CYS 14.A SG LEU 140.A O no hydrogen 4.031 N/A LEU 16.A N MET 13.A O no hydrogen 3.285 N/A SER 20.A N GLY 17.A O no hydrogen 3.300 N/A TYR 21.A N GLY 17.A O no hydrogen 3.121 N/A CYS 23.A SG GLY 182.A O no hydrogen 3.607 N/A ALA 29.A N ASP 25.A O no hydrogen 2.819 N/A LEU 30.A N ASN 26.A O no hydrogen 2.739 N/A THR 32.A OG1 GLN 31.A O no hydrogen 2.354 N/A LYS 35.A N THR 32.A O no hydrogen 3.189 N/A LYS 35.A NZ THR 42.A OG1 no hydrogen 3.378 N/A ASP 37.A N VAL 34.A O no hydrogen 3.224 N/A LYS 44.A N ASN 41.A OD1 no hydrogen 3.365 N/A PHE 45.A N ASN 41.A O no hydrogen 3.272 N/A LEU 47.A N LYS 44.A O no hydrogen 2.856 N/A TYR 49.A N MET 46.A O no hydrogen 3.390 N/A ALA 50.A N MET 46.A O no hydrogen 3.255 N/A TYR 52.A N TYR 49.A O no hydrogen 3.117 N/A SER 53.A N ALA 50.A O no hydrogen 3.168 N/A TRP 54.A N ALA 50.A O no hydrogen 2.987 N/A ASN 56.A N TRP 54.A O no hydrogen 2.762 N/A ASN 56.A ND2 GLU 115.A OE2 no hydrogen 2.841 N/A CYS 60.A N ASN 56.A O no hydrogen 2.743 N/A CYS 60.A SG ASN 56.A O no hydrogen 3.119 N/A CYS 60.A SG VAL 57.A O no hydrogen 3.083 N/A PHE 61.A N VAL 57.A O no hydrogen 2.965 N/A LEU 62.A N VAL 58.A O no hydrogen 2.893 N/A GLY 63.A N LEU 59.A O no hydrogen 2.899 N/A GLY 64.A N CYS 60.A O no hydrogen 2.920 N/A PHE 65.A N PHE 61.A O no hydrogen 2.927 N/A LEU 66.A N LEU 62.A O no hydrogen 2.890 N/A ILE 67.A N GLY 63.A O no hydrogen 2.925 N/A ASP 68.A N GLY 64.A O no hydrogen 2.934 N/A ARG 69.A N PHE 65.A O no hydrogen 2.904 N/A ILE 70.A N LEU 66.A O no hydrogen 2.909 N/A PHE 71.A N LEU 66.A O no hydrogen 3.094 N/A GLY 72.A N ILE 67.A O no hydrogen 3.241 N/A PHE 80.A N GLY 76.A O no hydrogen 3.195 N/A SER 81.A N THR 77.A O no hydrogen 2.941 N/A CYS 82.A N VAL 78.A O no hydrogen 3.209 N/A PHE 83.A N ILE 79.A O no hydrogen 2.922 N/A VAL 84.A N PHE 80.A O no hydrogen 2.906 N/A CYS 85.A N SER 81.A O no hydrogen 2.909 N/A CYS 85.A SG SER 81.A O no hydrogen 3.683 N/A CYS 85.A SG CYS 82.A O no hydrogen 2.966 N/A ILE 86.A N CYS 82.A O no hydrogen 2.916 N/A GLY 87.A N PHE 83.A O no hydrogen 2.904 N/A GLN 88.A N VAL 84.A O no hydrogen 2.938 N/A VAL 89.A N CYS 85.A O no hydrogen 2.909 N/A ILE 90.A N ILE 86.A O no hydrogen 2.916 N/A PHE 91.A N GLY 87.A O no hydrogen 2.917 N/A ALA 92.A N GLN 88.A O no hydrogen 2.948 N/A LEU 93.A N VAL 89.A O no hydrogen 2.877 N/A GLY 94.A N ILE 90.A O no hydrogen 2.875 N/A GLY 95.A N PHE 91.A O no hydrogen 2.926 N/A ILE 96.A N ALA 92.A O no hydrogen 2.917 N/A PHE 97.A N LEU 93.A O no hydrogen 2.908 N/A GLU 104.A N PHE 100.A O no hydrogen 2.819 N/A LEU 105.A N TRP 101.A O no hydrogen 3.037 N/A GLY 106.A N MET 103.A O no hydrogen 3.416 N/A ARG 107.A N GLU 104.A O no hydrogen 3.253 N/A PHE 108.A N LEU 105.A O no hydrogen 3.086 N/A VAL 109.A N GLY 106.A O no hydrogen 3.230 N/A PHE 110.A N GLY 106.A O no hydrogen 3.001 N/A GLY 111.A N ARG 107.A O no hydrogen 3.139 N/A GLY 113.A N VAL 109.A O no hydrogen 2.953 N/A GLY 114.A N PHE 110.A O no hydrogen 2.865 N/A GLU 115.A N GLY 111.A O no hydrogen 3.003 N/A SER 116.A N ILE 112.A O no hydrogen 2.921 N/A SER 116.A OG ILE 112.A O no hydrogen 2.611 N/A SER 116.A OG GLY 113.A O no hydrogen 3.030 N/A LEU 117.A N GLY 113.A O no hydrogen 2.888 N/A ALA 118.A N GLY 114.A O no hydrogen 2.900 N/A VAL 119.A N GLU 115.A O no hydrogen 2.961 N/A ALA 120.A N SER 116.A O no hydrogen 2.907 N/A GLN 121.A N LEU 117.A O no hydrogen 2.869 N/A ASN 122.A N ALA 118.A O no hydrogen 2.941 N/A THR 123.A N VAL 119.A O no hydrogen 2.965 N/A TYR 124.A N ALA 120.A O no hydrogen 2.892 N/A ALA 125.A N GLN 121.A O no hydrogen 2.931 N/A VAL 126.A N ASN 122.A O no hydrogen 2.964 N/A SER 127.A N THR 123.A O no hydrogen 2.865 N/A TRP 128.A N TYR 124.A O no hydrogen 2.968 N/A PHE 129.A N ALA 125.A O no hydrogen 3.091 N/A LEU 140.A N LEU 136.A O no hydrogen 2.997 N/A GLN 141.A N VAL 137.A O no hydrogen 2.903 N/A GLN 141.A NE2 TYR 21.A OH no hydrogen 3.142 N/A LEU 142.A N PHE 138.A O no hydrogen 2.909 N/A SER 143.A N GLY 139.A O no hydrogen 2.932 N/A SER 143.A OG ALA 258.A O no hydrogen 3.319 N/A MET 144.A N LEU 140.A O no hydrogen 2.896 N/A ILE 147.A N SER 143.A O no hydrogen 2.924 N/A GLY 148.A N MET 144.A O no hydrogen 2.919 N/A GLY 148.A N ALA 145.A O no hydrogen 3.294 N/A SER 149.A N ALA 145.A O no hydrogen 2.925 N/A SER 149.A OG ASP 25.A OD2 no hydrogen 2.589 N/A ASN 152.A N GLY 148.A O no hydrogen 2.932 N/A ASN 152.A ND2 PHE 22.A O no hydrogen 2.230 N/A MET 153.A N SER 149.A O no hydrogen 2.907 N/A ASN 154.A N THR 150.A O no hydrogen 2.965 N/A LEU 155.A N VAL 151.A O no hydrogen 2.867 N/A MET 156.A N ASN 152.A O no hydrogen 2.919 N/A TRP 158.A N ASN 154.A O no hydrogen 2.968 N/A LEU 159.A N LEU 155.A O no hydrogen 2.880 N/A TYR 160.A N MET 156.A O no hydrogen 2.948 N/A GLY 161.A N GLY 157.A O no hydrogen 3.480 N/A LYS 162.A N TRP 158.A O no hydrogen 2.946 N/A ILE 163.A N LEU 159.A O no hydrogen 2.858 N/A GLU 164.A N TYR 160.A O no hydrogen 2.937 N/A ALA 165.A N GLY 161.A O no hydrogen 2.904 N/A LEU 166.A N LYS 162.A O no hydrogen 2.909 N/A LEU 167.A N ILE 163.A O no hydrogen 2.898 N/A GLY 176.A N MET 173.A O no hydrogen 3.250 N/A THR 178.A N THR 174.A O no hydrogen 2.848 N/A THR 178.A OG1 THR 174.A O no hydrogen 2.344 N/A LEU 179.A N LEU 175.A O no hydrogen 2.748 N/A MET 180.A N GLY 176.A O no hydrogen 2.899 N/A ILE 181.A N VAL 177.A O no hydrogen 2.724 N/A GLY 182.A N THR 178.A O no hydrogen 3.185 N/A CYS 183.A N MET 180.A O no hydrogen 2.933 N/A CYS 186.A N CYS 183.A O no hydrogen 2.981 N/A CYS 186.A SG CYS 183.A O no hydrogen 3.082 N/A PHE 188.A N THR 185.A O no hydrogen 3.082 N/A SER 189.A OG LEU 16.A O no hydrogen 2.928 N/A LEU 190.A N CYS 186.A O no hydrogen 3.260 N/A ILE 191.A N ILE 187.A O no hydrogen 2.916 N/A CYS 192.A N PHE 188.A O no hydrogen 2.908 N/A CYS 192.A SG PHE 188.A O no hydrogen 3.362 N/A ALA 193.A N SER 189.A O no hydrogen 2.867 N/A LEU 194.A N LEU 190.A O no hydrogen 2.944 N/A ALA 195.A N ILE 191.A O no hydrogen 2.932 N/A LEU 196.A N CYS 192.A O no hydrogen 2.866 N/A ALA 197.A N ALA 193.A O no hydrogen 2.889 N/A TYR 198.A N LEU 194.A O no hydrogen 2.915 N/A LEU 199.A N ALA 195.A O no hydrogen 2.919 N/A ASP 200.A N LEU 196.A O no hydrogen 2.889 N/A ARG 201.A N ALA 197.A O no hydrogen 2.896 N/A ARG 202.A N TYR 198.A O no hydrogen 2.931 N/A ALA 203.A N LEU 199.A O no hydrogen 2.629 N/A GLU 204.A N ASP 200.A O no hydrogen 3.103 N/A SER 207.A OG PHE 206.A O no hydrogen 2.756 N/A ILE 211.A N LEU 208.A O no hydrogen 3.132 N/A VAL 213.A N PRO 209.A O no hydrogen 2.921 N/A PHE 214.A N LEU 210.A O no hydrogen 2.910 N/A VAL 215.A N ILE 211.A O no hydrogen 2.929 N/A ILE 216.A N LEU 212.A O no hydrogen 2.915 N/A CYS 217.A N VAL 213.A O no hydrogen 2.963 N/A CYS 217.A SG GLN 341.A OE1 no hydrogen 3.675 N/A VAL 218.A N PHE 214.A O no hydrogen 2.934 N/A CYS 219.A N VAL 215.A O no hydrogen 2.888 N/A TYR 220.A N ILE 216.A O no hydrogen 2.982 N/A TYR 220.A OH THR 285.A OG1 no hydrogen 2.853 N/A TYR 220.A OH SER 309.A OG no hydrogen 3.170 N/A TYR 221.A N CYS 217.A O no hydrogen 2.953 N/A VAL 222.A N VAL 218.A O no hydrogen 2.901 N/A ALA 223.A N CYS 219.A O no hydrogen 2.904 N/A ALA 223.A N TYR 220.A O no hydrogen 3.185 N/A PHE 227.A N VAL 224.A O no hydrogen 3.227 N/A GLY 229.A N PHE 225.A O no hydrogen 2.936 N/A LEU 230.A N PRO 226.A O no hydrogen 2.908 N/A GLY 231.A N PHE 227.A O no hydrogen 3.364 N/A LYS 232.A NZ SER 247.A OG no hydrogen 3.152 N/A MET 236.A N LYS 232.A O no hydrogen 3.347 N/A MET 236.A N VAL 233.A O no hydrogen 3.292 N/A GLU 237.A N PHE 234.A O no hydrogen 3.265 N/A LYS 238.A N PHE 234.A O no hydrogen 2.933 N/A SER 245.A OG GLN 244.A OE1 no hydrogen 2.835 N/A ALA 246.A N SER 242.A O no hydrogen 3.234 N/A SER 247.A N GLN 244.A O no hydrogen 3.331 N/A ALA 248.A N SER 245.A O no hydrogen 3.407 N/A SER 251.A N SER 247.A O no hydrogen 3.197 N/A ILE 256.A N ILE 252.A O no hydrogen 3.316 N/A SER 257.A N TYR 254.A O no hydrogen 2.950 N/A MET 260.A N SER 257.A O no hydrogen 3.095 N/A SER 261.A N SER 257.A O no hydrogen 2.846 N/A SER 261.A OG SER 257.A O no hydrogen 3.322 N/A SER 261.A OG SER 311.A O no hydrogen 3.232 N/A SER 261.A OG SER 311.A OG no hydrogen 2.560 N/A LEU 263.A N MET 260.A O no hydrogen 2.907 N/A PHE 264.A N MET 260.A O no hydrogen 3.326 N/A GLY 265.A N SER 261.A O no hydrogen 2.905 N/A LEU 266.A N PRO 262.A O no hydrogen 2.888 N/A LEU 267.A N LEU 263.A O no hydrogen 2.933 N/A VAL 268.A N PHE 264.A O no hydrogen 2.882 N/A THR 271.A OG1 LYS 270.A O no hydrogen 2.491 N/A ILE 276.A N LYS 273.A O no hydrogen 3.188 N/A TRP 277.A N LYS 273.A O no hydrogen 3.461 N/A VAL 278.A N ASN 274.A O no hydrogen 2.936 N/A LEU 279.A N ILE 275.A O no hydrogen 2.916 N/A TYR 280.A N ILE 276.A O no hydrogen 2.910 N/A ALA 281.A N TRP 277.A O no hydrogen 2.941 N/A VAL 282.A N VAL 278.A O no hydrogen 2.943 N/A ALA 283.A N LEU 279.A O no hydrogen 2.927 N/A ALA 284.A N TYR 280.A O no hydrogen 2.915 N/A THR 285.A N ALA 281.A O no hydrogen 2.940 N/A THR 285.A OG1 TYR 220.A OH no hydrogen 2.853 N/A THR 285.A OG1 ALA 281.A O no hydrogen 3.290 N/A THR 285.A OG1 SER 309.A OG no hydrogen 2.210 N/A LEU 286.A N VAL 282.A O no hydrogen 2.950 N/A VAL 287.A N ALA 283.A O no hydrogen 2.927 N/A SER 288.A N ALA 284.A O no hydrogen 2.893 N/A SER 288.A OG ALA 302.A O no hydrogen 2.305 N/A HIS 289.A N THR 285.A O no hydrogen 2.958 N/A MET 290.A N LEU 286.A O no hydrogen 2.926 N/A MET 291.A N VAL 287.A O no hydrogen 2.905 N/A LEU 292.A N SER 288.A O no hydrogen 2.916 N/A ALA 293.A N HIS 289.A O no hydrogen 2.909 N/A PHE 294.A N MET 290.A O no hydrogen 2.953 N/A MET 303.A N PRO 299.A O no hydrogen 2.892 N/A CYS 304.A N TRP 300.A O no hydrogen 2.909 N/A GLY 307.A N CYS 304.A O no hydrogen 3.110 N/A SER 309.A N LEU 305.A O no hydrogen 2.914 N/A SER 309.A OG TYR 220.A OH no hydrogen 3.170 N/A SER 309.A OG ALA 281.A O no hydrogen 2.473 N/A SER 309.A OG THR 285.A OG1 no hydrogen 2.210 N/A TYR 310.A N LEU 306.A O no hydrogen 2.887 N/A SER 311.A N GLY 307.A O no hydrogen 2.904 N/A SER 311.A OG SER 261.A OG no hydrogen 2.560 N/A LEU 312.A N PHE 308.A O no hydrogen 2.894 N/A ALA 314.A N TYR 310.A O no hydrogen 3.461 N/A CYS 315.A SG SER 261.A O no hydrogen 3.746 N/A CYS 315.A SG SER 311.A O no hydrogen 3.962 N/A CYS 315.A SG ALA 314.A O no hydrogen 2.907 N/A ALA 316.A N LEU 313.A O no hydrogen 3.430 N/A MET 320.A N LEU 317.A O no hydrogen 2.937 N/A VAL 321.A N TRP 318.A O no hydrogen 3.223 N/A ALA 322.A N PRO 319.A O no hydrogen 3.082 N/A PHE 323.A N MET 320.A O no hydrogen 3.211 N/A ILE 324.A N MET 320.A O no hydrogen 3.200 N/A THR 332.A N GLN 329.A O no hydrogen 3.462 N/A ALA 333.A N GLN 329.A O no hydrogen 3.469 N/A TYR 334.A N LEU 330.A O no hydrogen 2.956 N/A PHE 336.A N THR 332.A O no hydrogen 2.906 N/A MET 337.A N ALA 333.A O no hydrogen 2.937 N/A GLN 338.A N TYR 334.A O no hydrogen 2.944 N/A SER 339.A N GLY 335.A O no hydrogen 2.890 N/A SER 339.A OG VAL 57.A O no hydrogen 3.397 N/A ILE 340.A N PHE 336.A O no hydrogen 2.935 N/A GLN 341.A N MET 337.A O no hydrogen 2.950 N/A ASN 342.A N GLN 338.A O no hydrogen 2.941 N/A ASN 342.A ND2 GLU 115.A OE2 no hydrogen 2.554 N/A LEU 343.A N SER 339.A O no hydrogen 2.932 N/A GLY 344.A N ILE 340.A O no hydrogen 2.917 N/A LEU 345.A N GLN 341.A O no hydrogen 2.977 N/A ALA 346.A N ASN 342.A O no hydrogen 2.941 N/A VAL 347.A N LEU 343.A O no hydrogen 2.899 N/A ILE 348.A N GLY 344.A O no hydrogen 2.928 N/A ALA 349.A N LEU 345.A O no hydrogen 2.987 N/A ALA 352.A N ILE 348.A O no hydrogen 2.887 N/A GLY 353.A N ALA 349.A O no hydrogen 2.961 N/A MET 354.A N ILE 350.A O no hydrogen 2.879 N/A ILE 355.A N LEU 351.A O no hydrogen 2.915 N/A LEU 356.A N ALA 352.A O no hydrogen 2.927 N/A LYS 359.A N ILE 355.A O no hydrogen 2.929 N/A GLY 360.A N LEU 356.A O no hydrogen 2.825 N/A GLU 365.A N TYR 361.A O no hydrogen 3.293 N/A VAL 366.A N LEU 362.A O no hydrogen 2.911 N/A PHE 367.A N LEU 363.A O no hydrogen 2.882 N/A PHE 368.A N LEU 364.A O no hydrogen 2.932 N/A ILE 369.A N GLU 365.A O no hydrogen 2.895 N/A ALA 370.A N VAL 366.A O no hydrogen 2.917 N/A CYS 371.A N PHE 367.A O no hydrogen 2.956 N/A CYS 371.A SG PHE 367.A O no hydrogen 3.826 N/A VAL 372.A N PHE 368.A O no hydrogen 2.956 N/A SER 373.A N ILE 369.A O no hydrogen 2.857 N/A SER 373.A OG ILE 369.A O no hydrogen 3.505 N/A SER 373.A OG ALA 370.A O no hydrogen 2.494 N/A LEU 374.A N ALA 370.A O no hydrogen 2.945 N/A SER 375.A N CYS 371.A O no hydrogen 2.933 N/A LEU 376.A N VAL 372.A O no hydrogen 2.904 N/A LEU 377.A N SER 373.A O no hydrogen 2.909 N/A ALA 378.A N LEU 374.A O no hydrogen 2.944 N/A VAL 379.A N SER 375.A O no hydrogen 2.894 N/A VAL 380.A N LEU 376.A O no hydrogen 2.929 N/A CYS 381.A N LEU 377.A O no hydrogen 2.911 N/A CYS 381.A SG LEU 377.A O no hydrogen 3.334 N/A LEU 382.A N ALA 378.A O no hydrogen 2.901 N/A TYR 383.A N VAL 379.A O no hydrogen 2.937 N/A LEU 384.A N VAL 380.A O no hydrogen 2.896 N/A VAL 385.A N CYS 381.A O no hydrogen 2.913 N/A ASN 386.A N LEU 382.A O no hydrogen 3.041 N/A ARG 387.A N LEU 384.A O no hydrogen 3.210 N/A ALA 388.A N VAL 385.A O no hydrogen 3.357 N/A