Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8sf9_D.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): MET 1.A N GLU 12.A OE2 no hydrogen 2.873 N/A ARG 2.A N.A ILE 11.A O no hydrogen 2.826 N/A ARG 2.A N.B ILE 11.A O no hydrogen 2.825 N/A ILE 3.A N ILE 11.A O no hydrogen 2.790 N/A VAL 6.A N LEU 90.A O no hydrogen 2.853 N/A GLY 7.A N ASN 131.A OD1 no hydrogen 2.948 N/A LYS 8.A N LEU 5.A O no hydrogen 3.354 N/A LYS 8.A NZ GLY 87.A O no hydrogen 2.543 N/A LYS 8.A NZ ASN 89.A OD1 no hydrogen 2.958 N/A ILE 11.A N ILE 3.A O no hydrogen 2.949 N/A GLU 12.A N GLU 12.A OE1 no hydrogen 2.431 N/A LYS 14.A NZ ASP 15.A OD1 no hydrogen 3.501 N/A LYS 14.A NZ ASP 15.A OD2 no hydrogen 3.315 N/A ASP 15.A N GLU 12.A O no hydrogen 2.930 N/A ILE 16.A N SER 13.A O no hydrogen 3.398 N/A THR 19.A N PHE 275.A O no hydrogen 2.908 N/A THR 19.A OG1 GLY 17.A O no hydrogen 2.889 N/A LEU 20.A N THR 63.A O no hydrogen 3.015 N/A GLU 23.A N VAL 65.A O no hydrogen 2.964 N/A HIS 24.A ND1 THR 68.A OG1 no hydrogen 2.838 N/A LEU 25.A N ASP 66.A OD2 no hydrogen 3.229 N/A ARG 26.A NH1 GLU 45.A OE1 no hydrogen 2.831 N/A ARG 26.A NH2 ASP 75.A OD2 no hydrogen 2.989 N/A PHE 28.A N LEU 72.A O no hydrogen 2.840 N/A SER 29.A N ASP 248.A OD2 no hydrogen 2.994 N/A GLU 30.A N GLU 30.A OE1 no hydrogen 2.769 N/A ARG 33.A N SER 29.A O no hydrogen 3.038 N/A ARG 33.A NH1 GLU 45.A OE1 no hydrogen 3.022 N/A ARG 33.A NH1 GLU 45.A OE2 no hydrogen 2.929 N/A ARG 33.A NH2 GLU 45.A OE1 no hydrogen 2.847 N/A GLN 34.A N GLU 30.A O no hydrogen 3.018 N/A GLN 35.A N ALA 31.A O no hydrogen 3.058 N/A TRP 36.A N VAL 32.A O no hydrogen 2.836 N/A LEU 39.A N TRP 36.A O no hydrogen 3.154 N/A TYR 40.A N PRO 37.A O no hydrogen 3.088 N/A TYR 40.A OH ASP 248.A OD2 no hydrogen 2.374 N/A ASP 43.A N.A ASN 41.A OD1 no hydrogen 3.034 N/A ASP 43.A N.B ASN 41.A OD1 no hydrogen 3.035 N/A GLU 44.A N ASN 41.A OD1 no hydrogen 3.280 N/A GLU 45.A N ASN 41.A O no hydrogen 3.101 N/A PHE 46.A N GLU 42.A O no hydrogen 2.883 N/A ARG 47.A N.A ASP 43.A O.A no hydrogen 3.069 N/A ARG 47.A N.A ASP 43.A O.B no hydrogen 3.054 N/A ARG 47.A N.B ASP 43.A O.A no hydrogen 3.066 N/A ARG 47.A N.B ASP 43.A O.B no hydrogen 3.051 N/A ARG 47.A NE.B ASN 51.A OD1 no hydrogen 3.224 N/A ARG 47.A NH2.B ASN 51.A OD1 no hydrogen 3.157 N/A ASN 48.A N GLU 44.A O no hydrogen 2.948 N/A ALA 49.A N GLU 45.A O no hydrogen 2.939 N/A VAL 50.A N PHE 46.A O no hydrogen 2.878 N/A ASN 51.A N ARG 47.A O.A no hydrogen 3.039 N/A ASN 51.A N ARG 47.A O.B no hydrogen 3.043 N/A GLU 52.A N ASN 48.A O no hydrogen 3.068 N/A VAL 53.A N ALA 49.A O no hydrogen 3.053 N/A LYS 54.A N VAL 50.A O no hydrogen 2.954 N/A ARG 55.A N ASN 51.A O no hydrogen 2.992 N/A ALA 56.A N GLU 52.A O no hydrogen 3.076 N/A MET 57.A N VAL 53.A O no hydrogen 2.935 N/A GLN 58.A N.A LYS 54.A O no hydrogen 3.011 N/A GLN 58.A N.B LYS 54.A O no hydrogen 3.041 N/A GLN 58.A N.B ARG 55.A O no hydrogen 3.202 N/A PHE 59.A N ALA 56.A O no hydrogen 3.025 N/A GLY 60.A N MET 57.A O no hydrogen 2.999 N/A VAL 61.A N ALA 56.A O no hydrogen 3.049 N/A LYS 62.A N.A PHE 18.A O no hydrogen 2.859 N/A LYS 62.A N.B PHE 18.A O no hydrogen 2.865 N/A LYS 62.A NZ.B GLY 60.A O no hydrogen 2.694 N/A THR 63.A N PHE 18.A O no hydrogen 3.211 N/A THR 63.A OG1 ILE 16.A O no hydrogen 2.706 N/A ILE 64.A N ASN 89.A O no hydrogen 2.814 N/A VAL 65.A N LEU 20.A O no hydrogen 2.852 N/A ASP 66.A N VAL 91.A O no hydrogen 3.052 N/A THR 68.A N ASP 66.A OD1 no hydrogen 2.995 N/A THR 68.A OG1 HIS 24.A ND1 no hydrogen 2.838 N/A THR 68.A OG1 ARG 26.A O no hydrogen 3.420 N/A THR 68.A OG1 ASP 66.A OD1 no hydrogen 2.567 N/A GLY 71.A N GLU 30.A OE1 no hydrogen 3.287 N/A GLY 71.A N GLU 30.A OE2 no hydrogen 2.909 N/A LEU 72.A N VAL 69.A O no hydrogen 2.854 N/A GLY 73.A N GLU 30.A OE2 no hydrogen 3.081 N/A ARG 74.A NH1 GLY 93.A O no hydrogen 2.843 N/A ARG 74.A NH1 ASP 121.A OD2 no hydrogen 2.970 N/A ARG 74.A NH2 ASP 121.A OD2 no hydrogen 2.990 N/A ILE 76.A N GLN 127.A OE1 no hydrogen 2.842 N/A ARG 77.A N ASP 75.A OD1 no hydrogen 3.048 N/A ARG 77.A NH1 GLN 127.A O no hydrogen 2.948 N/A ARG 77.A NH2 GLN 127.A O no hydrogen 2.978 N/A PHE 78.A N ASP 75.A OD1 no hydrogen 3.165 N/A MET 79.A N ASP 75.A O no hydrogen 3.136 N/A GLU 80.A N.A ILE 76.A O no hydrogen 2.937 N/A GLU 80.A N.B ILE 76.A O no hydrogen 2.902 N/A LYS 81.A N.A ARG 77.A O no hydrogen 3.202 N/A LYS 81.A N.B ARG 77.A O no hydrogen 3.185 N/A VAL 82.A N PHE 78.A O no hydrogen 3.123 N/A VAL 83.A N MET 79.A O no hydrogen 3.060 N/A LYS 84.A N GLU 80.A O.A no hydrogen 3.068 N/A LYS 84.A N GLU 80.A O.B no hydrogen 2.913 N/A ALA 85.A N LYS 81.A O.A no hydrogen 3.156 N/A ALA 85.A N LYS 81.A O.B no hydrogen 3.202 N/A ALA 85.A N VAL 82.A O no hydrogen 3.164 N/A THR 86.A N VAL 83.A O no hydrogen 3.119 N/A THR 86.A OG1 VAL 82.A O no hydrogen 2.786 N/A GLY 87.A N VAL 83.A O no hydrogen 2.655 N/A ILE 88.A N THR 86.A OG1 no hydrogen 3.309 N/A ASN 89.A N LYS 62.A O.A no hydrogen 3.433 N/A ASN 89.A N LYS 62.A O.B no hydrogen 3.406 N/A ASN 89.A ND2 THR 63.A OG1 no hydrogen 3.378 N/A VAL 91.A N ILE 64.A O no hydrogen 2.944 N/A THR 94.A N PHE 135.A O no hydrogen 3.006 N/A THR 94.A OG1 ASP 121.A OD2 no hydrogen 2.720 N/A TYR 97.A N MET 70.A O no hydrogen 2.861 N/A TYR 97.A OH TYR 99.A OH no hydrogen 2.584 N/A TYR 99.A OH TYR 97.A OH no hydrogen 2.584 N/A TYR 99.A OH HIS 169.A NE2 no hydrogen 3.168 N/A LEU 102.A N ASP 147.A OD2 no hydrogen 2.871 N/A PHE 106.A N PRO 103.A O no hydrogen 3.047 N/A LEU 107.A N PHE 104.A O no hydrogen 2.962 N/A ARG 109.A N PHE 106.A O no hydrogen 3.017 N/A ARG 109.A NE TYR 105.A O no hydrogen 2.822 N/A ARG 109.A NH1 GLU 113.A OE2 no hydrogen 3.140 N/A SER 110.A N GLU 113.A OE1 no hydrogen 3.511 N/A GLU 113.A N SER 110.A O no hydrogen 3.077 N/A GLU 113.A N SER 110.A OG no hydrogen 3.187 N/A ILE 114.A N SER 110.A O no hydrogen 3.229 N/A ALA 115.A N ILE 111.A O no hydrogen 2.916 N/A ASP 116.A N ASP 112.A O no hydrogen 2.974 N/A LEU 117.A N ILE 114.A O no hydrogen 3.027 N/A PHE 118.A N ILE 114.A O no hydrogen 3.466 N/A ILE 119.A N ALA 115.A O no hydrogen 2.937 N/A HIS 120.A N ASP 116.A O no hydrogen 2.873 N/A ASP 121.A N LEU 117.A O no hydrogen 3.195 N/A ILE 122.A N PHE 118.A O no hydrogen 3.018 N/A LYS 123.A N ILE 119.A O no hydrogen 2.831 N/A LYS 123.A NZ GLU 161.A OE1.B no hydrogen 2.722 N/A LYS 123.A NZ GLU 161.A OE2.A no hydrogen 2.781 N/A GLU 124.A N HIS 120.A O no hydrogen 2.811 N/A GLY 125.A N HIS 120.A O no hydrogen 3.072 N/A ILE 126.A N ASN 131.A O no hydrogen 2.795 N/A GLN 127.A NE2 ARG 74.A O no hydrogen 3.106 N/A THR 129.A N ILE 126.A O no hydrogen 2.931 N/A THR 129.A OG1 ILE 126.A O no hydrogen 2.761 N/A ASN 131.A N THR 129.A OG1 no hydrogen 3.183 N/A ASN 131.A ND2 GLU 80.A OE1.A no hydrogen 3.257 N/A ASN 131.A ND2 GLU 80.A OE1.B no hydrogen 2.700 N/A ASN 131.A ND2 THR 129.A OG1 no hydrogen 3.227 N/A LYS 132.A NZ LYS 123.A O no hydrogen 3.295 N/A ALA 133.A N ASP 121.A O no hydrogen 2.988 N/A GLY 134.A N ALA 92.A O no hydrogen 2.938 N/A VAL 136.A N PRO 165.A O no hydrogen 3.011 N/A ALA 139.A N HIS 169.A O no hydrogen 2.962 N/A GLY 143.A N ASP 140.A O no hydrogen 2.974 N/A THR 145.A OG1 ILE 100.A O no hydrogen 2.825 N/A VAL 148.A N THR 145.A OG1 no hydrogen 3.180 N/A GLU 149.A N THR 145.A O no hydrogen 2.958 N/A LYS 150.A N LYS 146.A O no hydrogen 3.107 N/A LYS 150.A NZ ARG 109.A O no hydrogen 3.480 N/A VAL 151.A N ASP 147.A O no hydrogen 3.204 N/A ILE 152.A N VAL 148.A O no hydrogen 3.126 N/A LYS 153.A N GLU 149.A O no hydrogen 3.037 N/A ALA 154.A N LYS 150.A O no hydrogen 2.918 N/A ALA 155.A N VAL 151.A O no hydrogen 2.964 N/A ALA 156.A N ILE 152.A O no hydrogen 3.185 N/A ILE 157.A N LYS 153.A O no hydrogen 3.141 N/A ALA 158.A N ALA 154.A O no hydrogen 3.015 N/A ASN 159.A N ALA 155.A O no hydrogen 2.970 N/A ASN 159.A ND2 VAL 164.A O no hydrogen 2.789 N/A LYS 160.A N ALA 156.A O no hydrogen 2.917 N/A GLU 161.A N.A ILE 157.A O no hydrogen 3.154 N/A GLU 161.A N.A ALA 158.A O no hydrogen 3.274 N/A GLU 161.A N.B ILE 157.A O no hydrogen 3.156 N/A GLU 161.A N.B ALA 158.A O no hydrogen 3.273 N/A THR 162.A N ALA 158.A O no hydrogen 2.948 N/A THR 162.A OG1 ALA 158.A O no hydrogen 2.771 N/A LYS 163.A N ASN 159.A O no hydrogen 2.641 N/A VAL 164.A N THR 162.A OG1 no hydrogen 3.369 N/A ILE 166.A N LYS 193.A O no hydrogen 2.887 N/A ILE 167.A N VAL 136.A O no hydrogen 2.838 N/A THR 168.A N LEU 195.A O no hydrogen 2.874 N/A THR 168.A OG1 GLN 180.A OE1 no hydrogen 2.813 N/A HIS 169.A N ILE 137.A O no hydrogen 2.895 N/A HIS 169.A NE2 ASP 140.A OD1 no hydrogen 3.147 N/A SER 170.A N GLY 197.A O no hydrogen 3.293 N/A SER 170.A OG GLY 197.A O no hydrogen 3.022 N/A ASN 171.A N THR 176.A OG1 no hydrogen 3.014 N/A HIS 173.A N ASN 171.A OD1 no hydrogen 2.791 N/A ASN 174.A ND2 ASP 140.A O no hydrogen 2.791 N/A ASN 174.A ND2 GLU 141.A O no hydrogen 3.648 N/A THR 176.A N ASN 174.A OD1 no hydrogen 3.098 N/A THR 176.A OG1 ASN 171.A O no hydrogen 3.436 N/A THR 176.A OG1 ASN 174.A OD1 no hydrogen 2.803 N/A LEU 178.A N TYR 207.A OH no hydrogen 3.145 N/A GLU 179.A N ASN 175.A O no hydrogen 3.149 N/A GLN 180.A N THR 176.A O no hydrogen 2.841 N/A GLN 180.A NE2 HIS 169.A O no hydrogen 2.983 N/A GLN 181.A N GLY 177.A O no hydrogen 3.121 N/A GLN 181.A NE2 ILE 211.A O no hydrogen 2.980 N/A GLN 181.A NE2 SER 216.A OG no hydrogen 3.056 N/A ARG 182.A N LEU 178.A O no hydrogen 2.989 N/A ARG 182.A NE GLU 179.A OE2 no hydrogen 3.302 N/A ARG 182.A NH1 GLU 186.A OE2 no hydrogen 3.026 N/A ARG 182.A NH2 GLU 179.A OE1 no hydrogen 2.650 N/A ILE 183.A N GLU 179.A O no hydrogen 2.957 N/A LEU 184.A N GLN 180.A O no hydrogen 3.053 N/A THR 185.A N GLN 181.A O no hydrogen 2.946 N/A THR 185.A OG1 GLN 181.A O no hydrogen 2.828 N/A THR 185.A OG1 ARG 182.A O no hydrogen 2.955 N/A GLU 186.A N ARG 182.A O no hydrogen 2.900 N/A GLU 187.A N ILE 183.A O no hydrogen 3.213 N/A GLU 187.A N LEU 184.A O no hydrogen 3.127 N/A GLY 188.A N THR 185.A O no hydrogen 2.999 N/A VAL 189.A N LEU 184.A O no hydrogen 3.074 N/A GLY 192.A N ASP 190.A OD1 no hydrogen 2.908 N/A LYS 193.A N ASP 190.A O no hydrogen 2.813 N/A LYS 193.A NZ PHE 282.A O no hydrogen 2.769 N/A LYS 193.A NZ SER 284.A O no hydrogen 2.241 N/A ILE 194.A N PRO 191.A O no hydrogen 3.246 N/A LEU 195.A N ILE 166.A O no hydrogen 2.929 N/A ILE 196.A N PHE 217.A O no hydrogen 3.010 N/A HIS 198.A N ASP 221.A OD1 no hydrogen 2.786 N/A HIS 198.A ND1.A ASP 221.A O no hydrogen 3.157 N/A LEU 199.A N GLY 219.A O no hydrogen 3.024 N/A THR 202.A N LEU 199.A O no hydrogen 2.955 N/A ASN 204.A N THR 202.A OG1 no hydrogen 3.234 N/A TYR 207.A N ASN 204.A O no hydrogen 3.017 N/A TYR 207.A N ASN 204.A OD1 no hydrogen 3.195 N/A ILE 208.A N ASN 204.A O no hydrogen 3.389 N/A LYS 209.A N ILE 205.A O no hydrogen 2.776 N/A LYS 209.A NZ ASP 235.A OD2 no hydrogen 2.767 N/A LYS 210.A N ASP 206.A O no hydrogen 2.984 N/A ILE 211.A N TYR 207.A O no hydrogen 3.318 N/A ALA 212.A N ILE 208.A O no hydrogen 3.129 N/A ASP 213.A N LYS 209.A O no hydrogen 2.775 N/A LYS 214.A N.A LYS 210.A O no hydrogen 3.277 N/A LYS 214.A N.A ILE 211.A O no hydrogen 3.072 N/A LYS 214.A N.B LYS 210.A O no hydrogen 3.272 N/A LYS 214.A N.B ILE 211.A O no hydrogen 3.065 N/A GLY 215.A N ALA 212.A O no hydrogen 2.852 N/A SER 216.A OG PRO 191.A O no hydrogen 2.663 N/A PHE 217.A N ILE 194.A O no hydrogen 3.027 N/A ILE 218.A N LYS 240.A O no hydrogen 2.786 N/A GLY 219.A N ILE 196.A O no hydrogen 2.792 N/A LEU 220.A N MET 242.A O no hydrogen 2.979 N/A LYS 224.A NZ ASP 223.A OD2.A no hydrogen 3.004 N/A ARG 225.A NE LEU 220.A O no hydrogen 3.484 N/A ARG 225.A NH2 ASP 201.A OD1 no hydrogen 2.902 N/A ASN 226.A N VAL 222.A O no hydrogen 2.513 N/A GLU 227.A N ASP 223.A O no hydrogen 2.534 N/A THR 228.A N LYS 224.A O no hydrogen 2.863 N/A THR 228.A OG1 LYS 224.A O no hydrogen 2.886 N/A THR 229.A N ARG 225.A O no hydrogen 2.926 N/A THR 229.A OG1 ARG 225.A O no hydrogen 2.646 N/A LEU 230.A N ASN 226.A O no hydrogen 2.736 N/A ARG 231.A N GLU 227.A O no hydrogen 2.692 N/A LEU 232.A N THR 228.A O no hydrogen 2.812 N/A ILE 233.A N THR 229.A O no hydrogen 2.962 N/A LYS 234.A N LEU 230.A O no hydrogen 2.871 N/A ASP 235.A N ARG 231.A O no hydrogen 3.157 N/A ASP 235.A N LEU 232.A O no hydrogen 3.192 N/A GLY 236.A N ILE 233.A O no hydrogen 2.984 N/A TYR 237.A N LEU 232.A O no hydrogen 3.021 N/A TYR 237.A OH ASP 213.A OD1 no hydrogen 3.014 N/A LYS 240.A N TYR 237.A O no hydrogen 3.104 N/A LYS 240.A NZ ALA 212.A O no hydrogen 2.814 N/A ILE 241.A N SER 238.A O no hydrogen 3.210 N/A MET 242.A N ILE 218.A O no hydrogen 3.012 N/A SER 244.A OG HIS 22.A O no hydrogen 2.082 N/A ASP 246.A N HIS 22.A O no hydrogen 3.252 N/A SER 249.A OG THR 251.A OG1 no hydrogen 2.883 N/A THR 250.A N GLU 52.A OE1 no hydrogen 3.422 N/A THR 250.A OG1.A GLU 23.A OE2 no hydrogen 3.086 N/A THR 250.A OG1.A GLU 52.A OE1 no hydrogen 3.282 N/A THR 250.A OG1.A HIS 245.A NE2 no hydrogen 2.974 N/A THR 250.A OG1.B GLU 52.A O no hydrogen 3.408 N/A THR 250.A OG1.B GLU 52.A OE1 no hydrogen 2.549 N/A THR 251.A OG1 SER 249.A OG no hydrogen 2.883 N/A PHE 254.A N THR 251.A O no hydrogen 2.686 N/A GLU 255.A N THR 251.A O no hydrogen 2.558 N/A ASP 256.A N LEU 252.A O no hydrogen 3.003 N/A THR 257.A N LEU 252.A O no hydrogen 3.127 N/A ILE 258.A N ILE 253.A O no hydrogen 2.836 N/A PHE 260.A N ASP 256.A O no hydrogen 2.941 N/A LEU 261.A N THR 257.A O no hydrogen 2.919 N/A LYS 262.A N ILE 258.A O no hydrogen 2.961 N/A ARG 263.A N PRO 259.A O no hydrogen 3.184 N/A ASN 264.A N LEU 261.A O no hydrogen 2.842 N/A GLY 265.A N LYS 262.A O no hydrogen 3.310 N/A VAL 270.A N ASN 267.A OD1 no hydrogen 3.228 N/A ALA 272.A N GLU 268.A O no hydrogen 3.072 N/A THR 273.A N GLU 269.A O no hydrogen 3.179 N/A THR 273.A OG1 GLU 269.A O no hydrogen 2.808 N/A ILE 274.A N.A VAL 270.A O no hydrogen 3.133 N/A ILE 274.A N.B VAL 270.A O no hydrogen 3.152 N/A PHE 275.A N ILE 271.A O no hydrogen 3.153 N/A LYS 276.A N ALA 272.A O no hydrogen 2.797 N/A GLU 277.A N.A ALA 272.A O no hydrogen 3.104 N/A GLU 277.A N.B ALA 272.A O no hydrogen 3.102 N/A ASN 278.A N THR 273.A O no hydrogen 2.791 N/A ASN 278.A ND2 SER 238.A O no hydrogen 2.937 N/A ASN 278.A ND2 ILE 241.A O no hydrogen 2.431 N/A LYS 280.A N LYS 276.A O no hydrogen 3.213 N/A LYS 281.A N.A GLU 277.A O.A no hydrogen 3.041 N/A LYS 281.A N.A GLU 277.A O.B no hydrogen 3.080 N/A LYS 281.A N.B GLU 277.A O.A no hydrogen 3.068 N/A LYS 281.A N.B GLU 277.A O.B no hydrogen 3.107 N/A LYS 281.A NZ.A ASP 239.A O no hydrogen 3.100 N/A LYS 281.A NZ.A ASN 278.A OD1 no hydrogen 3.090 N/A PHE 282.A N ASN 278.A O no hydrogen 3.012 N/A PHE 283.A N PRO 279.A O no hydrogen 3.066 N/A SER 284.A N LYS 281.A O.A no hydrogen 3.013 N/A SER 284.A N LYS 281.A O.B no hydrogen 3.243 N/A SER 284.A OG LYS 280.A O no hydrogen 2.256 N/A