Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8si0_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LYS 4.A NZ GLU 333.A O no hydrogen 2.935 N/A LEU 5.A N GLY 1.A O no hydrogen 3.225 N/A ARG 6.A N ALA 2.A O no hydrogen 2.519 N/A ARG 6.A NH1 ARG 275.A O no hydrogen 3.409 N/A ALA 7.A N SER 3.A O no hydrogen 2.822 N/A VAL 8.A N LYS 4.A O no hydrogen 3.084 N/A LEU 9.A N LEU 5.A O no hydrogen 3.059 N/A GLU 10.A N ARG 6.A O no hydrogen 2.875 N/A LYS 11.A N ALA 7.A O no hydrogen 2.907 N/A LYS 11.A NZ GLU 339.A O no hydrogen 3.422 N/A LEU 12.A N VAL 8.A O no hydrogen 2.833 N/A LYS 13.A N LEU 9.A O no hydrogen 3.105 N/A LYS 13.A NZ GLU 10.A OE1 no hydrogen 3.442 N/A LEU 14.A N LYS 11.A O no hydrogen 2.780 N/A SER 15.A N LEU 12.A O no hydrogen 3.258 N/A SER 15.A OG LEU 12.A O no hydrogen 3.220 N/A ARG 16.A N LYS 13.A O no hydrogen 2.781 N/A ASP 18.A N SER 15.A O no hydrogen 3.178 N/A ILE 19.A N SER 15.A O no hydrogen 3.208 N/A SER 20.A OG ARG 16.A O no hydrogen 3.287 N/A SER 20.A OG ASP 17.A O no hydrogen 2.855 N/A THR 21.A N ASP 17.A O no hydrogen 3.349 N/A ALA 22.A N ASP 18.A O no hydrogen 3.214 N/A ALA 23.A N ILE 19.A O no hydrogen 2.892 N/A GLY 24.A N SER 20.A O no hydrogen 2.954 N/A MET 25.A N THR 21.A O no hydrogen 3.163 N/A VAL 26.A N ALA 22.A O no hydrogen 3.098 N/A LYS 27.A N ALA 23.A O no hydrogen 2.774 N/A LYS 27.A NZ ASP 31.A OD1 no hydrogen 3.193 N/A GLY 28.A N GLY 24.A O no hydrogen 3.219 N/A VAL 30.A N VAL 26.A O no hydrogen 2.930 N/A ASP 31.A N LYS 27.A O no hydrogen 2.774 N/A HIS 32.A N GLY 28.A O no hydrogen 3.164 N/A LEU 33.A N VAL 29.A O no hydrogen 2.797 N/A LEU 34.A N VAL 30.A O no hydrogen 2.885 N/A LEU 35.A N ASP 31.A O no hydrogen 3.263 N/A ARG 36.A N HIS 32.A O no hydrogen 3.367 N/A ARG 36.A NH1 ASP 115.A OD1 no hydrogen 3.233 N/A ARG 36.A NH2 ASP 115.A OD1 no hydrogen 3.324 N/A LEU 37.A N LEU 33.A O no hydrogen 2.989 N/A LYS 38.A N LEU 34.A O no hydrogen 3.054 N/A CYS 39.A N ARG 36.A O no hydrogen 3.393 N/A CYS 39.A SG LEU 35.A O no hydrogen 3.532 N/A ASP 40.A N LEU 37.A O no hydrogen 3.000 N/A ALA 42.A N ASP 40.A OD1 no hydrogen 2.663 N/A VAL 46.A N PHE 43.A O no hydrogen 3.019 N/A GLY 47.A N LYS 64.A O no hydrogen 3.114 N/A LEU 49.A N MET 62.A O no hydrogen 3.041 N/A SER 54.A N GLU 58.A O no hydrogen 3.081 N/A SER 54.A OG GLU 58.A O no hydrogen 3.451 N/A GLU 58.A N ALA 55.A O no hydrogen 3.012 N/A PHE 59.A N SER 142.A O no hydrogen 2.847 N/A VAL 61.A N ASP 144.A O no hydrogen 2.720 N/A PHE 63.A N THR 146.A O no hydrogen 2.805 N/A LEU 65.A N ALA 148.A O no hydrogen 2.609 N/A ARG 69.A NH1 SER 153.A OG no hydrogen 2.918 N/A GLN 71.A N LYS 85.A O no hydrogen 2.809 N/A GLU 73.A N PHE 83.A O no hydrogen 3.324 N/A TYR 75.A N TYR 81.A O no hydrogen 2.866 N/A ASN 77.A N SER 76.A OG no hydrogen 2.539 N/A THR 78.A N TYR 75.A O no hydrogen 3.342 N/A THR 78.A OG1 TYR 75.A O no hydrogen 2.328 N/A ARG 79.A NE GLU 305.A OE1 no hydrogen 2.747 N/A ARG 79.A NH1 GLU 74.A OE2 no hydrogen 2.785 N/A ARG 79.A NH2 GLU 305.A OE1 no hydrogen 3.417 N/A TYR 82.A N TRP 193.A O no hydrogen 2.725 N/A TYR 82.A OH ARG 79.A O no hydrogen 2.805 N/A PHE 83.A N GLU 73.A O no hydrogen 2.983 N/A LYS 85.A N GLN 71.A O no hydrogen 3.219 N/A LYS 85.A NZ GLU 94.A OE1 no hydrogen 3.113 N/A PHE 90.A N LEU 87.A O no hydrogen 2.910 N/A LEU 91.A N SER 88.A O no hydrogen 2.655 N/A GLU 92.A N ILE 95.A O no hydrogen 2.801 N/A LEU 96.A N VAL 84.A O no hydrogen 2.778 N/A SER 97.A N PHE 90.A O no hydrogen 3.028 N/A SER 99.A OG SER 97.A OG no hydrogen 2.970 N/A LYS 100.A N SER 97.A OG no hydrogen 2.943 N/A MET 101.A N SER 97.A O no hydrogen 2.944 N/A LEU 102.A N ALA 98.A O no hydrogen 2.698 N/A SER 103.A N LYS 100.A O no hydrogen 3.102 N/A SER 103.A OG SER 99.A O no hydrogen 2.949 N/A LYS 104.A N LYS 100.A O no hydrogen 3.319 N/A PHE 105.A N MET 101.A O no hydrogen 3.422 N/A ARG 106.A N LEU 102.A O no hydrogen 3.166 N/A LYS 107.A N SER 103.A O no hydrogen 2.884 N/A ILE 108.A N LYS 104.A O no hydrogen 3.141 N/A ILE 109.A N PHE 105.A O no hydrogen 3.221 N/A LYS 110.A N ARG 106.A O no hydrogen 3.090 N/A GLU 111.A N LYS 107.A O no hydrogen 3.164 N/A GLU 112.A N ILE 108.A O no hydrogen 3.156 N/A ILE 113.A N LYS 110.A O no hydrogen 3.493 N/A THR 119.A OG1 ASP 118.A OD2 no hydrogen 2.943 N/A ILE 122.A N LEU 136.A O no hydrogen 2.969 N/A LYS 124.A N THR 134.A O no hydrogen 2.918 N/A LYS 124.A NZ ARG 125.A O no hydrogen 3.443 N/A LYS 126.A NZ ASP 144.A OD1 no hydrogen 3.348 N/A LYS 126.A NZ ASP 144.A OD2 no hydrogen 3.244 N/A ALA 132.A N SER 130.A OG no hydrogen 3.177 N/A VAL 133.A N ILE 145.A O no hydrogen 2.738 N/A LEU 135.A N VAL 143.A O no hydrogen 2.943 N/A LEU 136.A N ILE 122.A O no hydrogen 2.892 N/A ILE 137.A N ILE 141.A O no hydrogen 2.529 N/A SER 138.A N ASP 120.A O no hydrogen 2.677 N/A SER 138.A OG ILE 137.A O no hydrogen 2.812 N/A LYS 140.A N ILE 137.A O no hydrogen 3.333 N/A ILE 141.A N ILE 137.A O no hydrogen 3.125 N/A SER 142.A N ASN 57.A O no hydrogen 3.188 N/A VAL 143.A N LEU 135.A O no hydrogen 3.115 N/A ASP 144.A N PHE 59.A O no hydrogen 2.538 N/A ILE 145.A N VAL 133.A O no hydrogen 3.040 N/A THR 146.A N VAL 61.A O no hydrogen 2.951 N/A ALA 148.A N PHE 63.A O no hydrogen 2.776 N/A LEU 149.A N LEU 184.A O no hydrogen 3.012 N/A GLU 150.A N LEU 65.A O no hydrogen 2.832 N/A SER 151.A N PHE 182.A O no hydrogen 3.096 N/A SER 153.A N SER 151.A OG no hydrogen 3.349 N/A SER 153.A OG SER 151.A OG no hydrogen 2.930 N/A TRP 155.A NE1 LYS 180.A O no hydrogen 2.903 N/A SER 158.A OG ARG 79.A O no hydrogen 2.736 N/A SER 158.A OG TYR 82.A OH no hydrogen 2.627 N/A THR 159.A N PRO 156.A O no hydrogen 2.940 N/A THR 159.A OG1 PRO 156.A O no hydrogen 2.937 N/A GLN 160.A N ALA 157.A O no hydrogen 2.964 N/A GLY 162.A N THR 159.A O no hydrogen 3.233 N/A LEU 163.A N TYR 301.A O no hydrogen 2.818 N/A ILE 165.A N LEU 163.A O no hydrogen 2.738 N/A GLN 166.A N GLN 166.A OE1 no hydrogen 2.756 N/A TRP 168.A N ILE 165.A O no hydrogen 2.945 N/A TRP 168.A NE1 HIS 208.A O no hydrogen 2.553 N/A VAL 173.A N SER 170.A O no hydrogen 2.749 N/A ARG 174.A N SER 170.A O no hydrogen 3.219 N/A ARG 174.A NE LEU 163.A O no hydrogen 2.954 N/A ARG 174.A NH2 GLN 160.A O no hydrogen 2.790 N/A ARG 174.A NH2 GLY 162.A O no hydrogen 2.763 N/A LYS 175.A N ALA 171.A O no hydrogen 3.327 N/A GLN 176.A N LYS 172.A O no hydrogen 3.035 N/A LEU 177.A N VAL 173.A O no hydrogen 2.824 N/A ARG 178.A N ARG 174.A O no hydrogen 2.985 N/A ARG 178.A NH2 THR 159.A O no hydrogen 2.987 N/A LEU 179.A N LYS 175.A O no hydrogen 3.108 N/A LEU 179.A N GLN 176.A O no hydrogen 3.210 N/A LYS 180.A N LEU 177.A O no hydrogen 3.222 N/A LYS 180.A NZ GLU 203.A OE1 no hydrogen 2.779 N/A LYS 180.A NZ GLU 203.A OE2 no hydrogen 3.090 N/A PHE 182.A N SER 151.A O no hydrogen 3.290 N/A TYR 183.A N SER 196.A O no hydrogen 3.272 N/A TYR 183.A OH GLU 150.A OE1 no hydrogen 2.577 N/A LEU 184.A N LEU 149.A O no hydrogen 3.071 N/A VAL 185.A N ARG 194.A O no hydrogen 2.892 N/A LYS 187.A N VAL 185.A O no hydrogen 2.646 N/A HIS 188.A ND1 THR 192.A O no hydrogen 3.103 N/A THR 192.A OG1 HIS 188.A O no hydrogen 2.458 N/A TRP 193.A N TYR 82.A O no hydrogen 3.001 N/A TRP 193.A NE1 LEU 96.A O no hydrogen 3.056 N/A ARG 194.A N VAL 185.A O no hydrogen 2.912 N/A ARG 194.A NH1 LEU 195.A O no hydrogen 2.759 N/A LEU 195.A N ALA 80.A O no hydrogen 3.072 N/A SER 196.A N TYR 183.A O no hydrogen 2.671 N/A SER 198.A OG SER 196.A OG no hydrogen 3.238 N/A HIS 199.A NE2 PRO 181.A O no hydrogen 2.828 N/A GLU 201.A N PHE 197.A O no hydrogen 2.925 N/A LYS 202.A N SER 198.A O no hydrogen 3.041 N/A GLU 203.A N HIS 199.A O no hydrogen 3.242 N/A ILE 204.A N ILE 200.A O no hydrogen 3.034 N/A LEU 205.A N GLU 201.A O no hydrogen 3.121 N/A ASN 206.A N LYS 202.A O no hydrogen 3.039 N/A ASN 207.A N GLU 203.A O no hydrogen 2.626 N/A HIS 208.A ND1 LEU 205.A O no hydrogen 2.881 N/A LYS 210.A N ASP 270.A OD1 no hydrogen 2.749 N/A LYS 210.A NZ ASN 167.A O no hydrogen 2.609 N/A LYS 210.A NZ TRP 168.A O no hydrogen 2.628 N/A SER 211.A N ASP 270.A OD2 no hydrogen 2.778 N/A SER 211.A OG GLU 220.A OE1 no hydrogen 2.719 N/A SER 211.A OG GLU 220.A OE2 no hydrogen 3.546 N/A THR 213.A N SER 211.A OG no hydrogen 2.841 N/A THR 213.A OG1 SER 211.A OG no hydrogen 2.652 N/A THR 213.A OG1 GLU 220.A OE1 no hydrogen 3.546 N/A THR 213.A OG1 GLU 220.A OE2 no hydrogen 2.532 N/A CYS 214.A N SER 211.A O no hydrogen 3.090 N/A CYS 214.A SG HIS 208.A NE2 no hydrogen 3.744 N/A CYS 215.A N GLU 220.A O no hydrogen 2.687 N/A CYS 215.A SG HIS 208.A NE2 no hydrogen 3.441 N/A CYS 215.A SG GLU 220.A O no hydrogen 4.022 N/A GLU 216.A N THR 213.A O no hydrogen 3.295 N/A ASN 217.A ND2 GLU 220.A OE2 no hydrogen 3.336 N/A LYS 218.A NZ GLU 219.A OE2 no hydrogen 2.785 N/A GLU 219.A N ASN 217.A OD1 no hydrogen 2.903 N/A GLU 220.A N ASN 217.A O no hydrogen 3.009 N/A LYS 221.A NZ CYS 215.A O no hydrogen 3.255 N/A CYS 222.A SG HIS 208.A NE2 no hydrogen 3.267 N/A CYS 223.A N TRP 273.A O no hydrogen 2.865 N/A CYS 223.A SG TRP 273.A O no hydrogen 3.460 N/A CYS 223.A SG ASP 274.A O no hydrogen 3.618 N/A ARG 224.A NH1 ASP 270.A OD1 no hydrogen 2.938 N/A ARG 224.A NH2 ASP 270.A OD1 no hydrogen 2.897 N/A LYS 225.A NZ ASN 206.A OD1 no hydrogen 3.162 N/A CYS 227.A N CYS 223.A O no hydrogen 2.889 N/A CYS 227.A SG CYS 223.A O no hydrogen 3.273 N/A LEU 228.A N ARG 224.A O no hydrogen 3.059 N/A LYS 229.A N LYS 225.A O no hydrogen 2.857 N/A LEU 230.A N ASP 226.A O no hydrogen 2.902 N/A MET 231.A N CYS 227.A O no hydrogen 2.932 N/A LYS 232.A N LEU 228.A O no hydrogen 2.823 N/A TYR 233.A N LYS 229.A O no hydrogen 2.804 N/A LEU 234.A N LEU 230.A O no hydrogen 2.694 N/A LEU 235.A N MET 231.A O no hydrogen 3.150 N/A GLU 236.A N LYS 232.A O no hydrogen 3.150 N/A GLN 237.A N TYR 233.A O no hydrogen 2.990 N/A LEU 238.A N LEU 234.A O no hydrogen 3.092 N/A LYS 239.A N LEU 235.A O no hydrogen 2.743 N/A LYS 239.A NZ PHE 251.A O no hydrogen 2.585 N/A GLU 240.A N GLU 236.A O no hydrogen 2.928 N/A ARG 241.A N GLN 237.A O no hydrogen 3.382 N/A PHE 242.A N LEU 238.A O no hydrogen 3.135 N/A LYS 243.A N GLU 240.A O no hydrogen 2.945 N/A ASP 244.A N ARG 241.A O no hydrogen 3.472 N/A LYS 246.A NZ LYS 243.A O no hydrogen 2.750 N/A PHE 251.A N LEU 248.A O no hydrogen 3.275 N/A SER 252.A N HIS 255.A ND1 no hydrogen 2.988 N/A TYR 254.A OH GLU 201.A OE2 no hydrogen 2.779 N/A VAL 256.A N SER 252.A O no hydrogen 3.499 N/A LYS 257.A N SER 253.A O no hydrogen 2.693 N/A LYS 257.A NZ GLU 201.A OE1 no hydrogen 3.097 N/A THR 258.A N TYR 254.A O no hydrogen 2.616 N/A THR 258.A OG1 TYR 254.A O no hydrogen 2.896 N/A ALA 259.A N HIS 255.A O no hydrogen 2.805 N/A PHE 260.A N VAL 256.A O no hydrogen 2.967 N/A PHE 261.A N LYS 257.A O no hydrogen 3.104 N/A HIS 262.A N THR 258.A O no hydrogen 3.229 N/A HIS 262.A NE2 GLU 299.A O no hydrogen 2.673 N/A VAL 263.A N ALA 259.A O no hydrogen 3.089 N/A CYS 264.A N PHE 260.A O no hydrogen 2.921 N/A CYS 264.A SG PHE 260.A O no hydrogen 3.772 N/A THR 265.A N PHE 261.A O no hydrogen 2.939 N/A THR 265.A OG1 ARG 164.A O no hydrogen 3.139 N/A THR 265.A OG1 TYR 301.A OH no hydrogen 2.663 N/A GLN 266.A N HIS 262.A O no hydrogen 3.038 N/A ASN 267.A N VAL 263.A O no hydrogen 2.804 N/A ASN 267.A ND2 VAL 263.A O no hydrogen 3.241 N/A GLN 269.A N GLN 272.A OE1 no hydrogen 3.011 N/A GLN 272.A N GLN 269.A O no hydrogen 3.002 N/A TRP 273.A N ASP 270.A O no hydrogen 2.685 N/A TRP 273.A NE1 ASN 267.A O no hydrogen 2.843 N/A LYS 276.A N ASP 274.A OD1 no hydrogen 3.107 N/A ASP 277.A N ASP 274.A O no hydrogen 2.830 N/A LEU 278.A N ARG 275.A O no hydrogen 3.130 N/A CYS 281.A N ASP 277.A O no hydrogen 2.754 N/A CYS 281.A SG GLN 272.A O no hydrogen 3.198 N/A CYS 281.A SG ASP 274.A O no hydrogen 3.933 N/A CYS 281.A SG ASP 277.A O no hydrogen 3.133 N/A PHE 282.A N LEU 278.A O no hydrogen 2.829 N/A ASP 283.A N GLY 279.A O no hydrogen 3.005 N/A ASN 284.A N LEU 280.A O no hydrogen 2.962 N/A CYS 285.A N CYS 281.A O no hydrogen 3.267 N/A CYS 285.A SG CYS 281.A O no hydrogen 3.532 N/A VAL 286.A N PHE 282.A O no hydrogen 3.029 N/A THR 287.A N ASP 283.A O no hydrogen 2.719 N/A THR 287.A OG1 ASN 284.A O no hydrogen 3.557 N/A TYR 288.A N ASN 284.A O no hydrogen 3.191 N/A PHE 289.A N CYS 285.A O no hydrogen 3.018 N/A LEU 290.A N VAL 286.A O no hydrogen 3.008 N/A GLN 291.A N THR 287.A O no hydrogen 2.920 N/A CYS 292.A N TYR 288.A O no hydrogen 2.960 N/A CYS 292.A SG TYR 288.A O no hydrogen 3.325 N/A LEU 293.A N PHE 289.A O no hydrogen 2.944 N/A ARG 294.A N LEU 290.A O no hydrogen 2.704 N/A THR 295.A N GLN 291.A O no hydrogen 2.857 N/A THR 295.A OG1 GLN 291.A O no hydrogen 2.866 N/A THR 295.A OG1 CYS 292.A O no hydrogen 3.460 N/A GLU 296.A N LEU 293.A O no hydrogen 2.661 N/A LYS 297.A N CYS 292.A O no hydrogen 2.877 N/A LYS 297.A NZ GLU 299.A OE2 no hydrogen 2.682 N/A LEU 298.A N ASN 307.A OD1 no hydrogen 2.816 N/A ASN 300.A N PHE 306.A O no hydrogen 3.046 N/A TYR 301.A OH THR 265.A OG1 no hydrogen 2.663 N/A PHE 302.A N ASN 300.A OD1 no hydrogen 2.713 N/A ILE 303.A N ASN 300.A OD1 no hydrogen 2.717 N/A PHE 306.A N ILE 303.A O no hydrogen 2.919 N/A ASN 307.A ND2 GLU 296.A O no hydrogen 3.206 N/A LEU 308.A N LEU 298.A O no hydrogen 2.977 N/A PHE 309.A N ASN 307.A OD1 no hydrogen 3.015 N/A SER 310.A N ASN 307.A O no hydrogen 3.264 N/A SER 310.A OG ASN 307.A O no hydrogen 3.480 N/A LEU 313.A N SER 310.A O no hydrogen 3.299 N/A ILE 314.A N SER 310.A O no hydrogen 3.290 N/A LYS 316.A NZ GLU 296.A OE1 no hydrogen 3.512 N/A LYS 316.A NZ GLU 296.A OE2 no hydrogen 3.068 N/A SER 318.A N ASP 315.A OD1 no hydrogen 2.906 N/A SER 318.A OG ASP 315.A OD1 no hydrogen 3.001 N/A LYS 319.A NZ PHE 309.A O no hydrogen 3.180 N/A LYS 319.A NZ ILE 314.A O no hydrogen 2.346 N/A LYS 319.A NZ ASP 315.A O no hydrogen 3.341 N/A GLU 320.A N LYS 316.A O no hydrogen 3.053 N/A PHE 321.A N ARG 317.A O no hydrogen 3.050 N/A LEU 322.A N SER 318.A O no hydrogen 3.080 N/A THR 323.A N LYS 319.A O no hydrogen 2.836 N/A THR 323.A OG1 LYS 319.A O no hydrogen 2.820 N/A LYS 324.A N GLU 320.A O no hydrogen 2.998 N/A LYS 324.A NZ GLU 327.A OE2 no hydrogen 3.439 N/A GLN 325.A N PHE 321.A O no hydrogen 3.135 N/A GLN 325.A NE2 PHE 321.A O no hydrogen 3.066 N/A ILE 326.A N LEU 322.A O no hydrogen 2.899 N/A GLU 327.A N THR 323.A O no hydrogen 2.856 N/A TYR 328.A N LYS 324.A O no hydrogen 3.063 N/A GLU 329.A N GLN 325.A O no hydrogen 2.927 N/A ARG 330.A N ILE 326.A O no hydrogen 2.880 N/A ARG 330.A NE ASP 283.A OD1 no hydrogen 2.502 N/A ARG 330.A NH2 ASP 283.A OD1 no hydrogen 3.010 N/A ASN 331.A N GLU 327.A O no hydrogen 2.987 N/A ASN 332.A N GLU 329.A O no hydrogen 3.404 N/A PHE 334.A N GLU 329.A O no hydrogen 2.826 N/A VAL 336.A N GLU 329.A OE1 no hydrogen 3.421 N/A PHE 337.A N PHE 334.A O no hydrogen 2.986 N/A ASP 338.A N PRO 335.A O no hydrogen 3.185 N/A