Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8t7t_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LEU 5.A N LEU 1.A O no hydrogen 2.861 N/A HIS 6.A N HIS 2.A O no hydrogen 2.895 N/A HIS 7.A N GLU 3.A O no hydrogen 2.914 N/A THR 8.A N VAL 4.A O no hydrogen 2.899 N/A LEU 9.A N LEU 5.A O no hydrogen 2.897 N/A THR 10.A N HIS 6.A O no hydrogen 2.910 N/A GLY 14.A N ASN 11.A O no hydrogen 3.019 N/A ARG 18.A N GLY 14.A O no hydrogen 3.242 N/A THR 19.A N LYS 15.A O no hydrogen 2.889 N/A MET 20.A N ALA 16.A O no hydrogen 2.905 N/A MET 21.A N TYR 17.A O no hydrogen 2.900 N/A ALA 22.A N ARG 18.A O no hydrogen 2.913 N/A GLN 23.A N THR 19.A O no hydrogen 2.904 N/A ILE 24.A N MET 20.A O no hydrogen 2.876 N/A PHE 25.A N MET 21.A O no hydrogen 3.206 N/A PHE 25.A N ALA 22.A O no hydrogen 3.301 N/A SER 26.A N GLN 23.A O no hydrogen 3.390 N/A SER 26.A OG ALA 22.A O no hydrogen 3.474 N/A GLN 27.A NE2 ILE 24.A O no hydrogen 2.519 N/A ILE 33.A N SER 30.A OG no hydrogen 3.369 N/A ASP 34.A N SER 30.A O no hydrogen 3.099 N/A TYR 35.A N PRO 31.A O no hydrogen 2.900 N/A THR 36.A N ALA 32.A O no hydrogen 3.293 N/A THR 36.A OG1 SER 39.A OG no hydrogen 3.376 N/A TYR 37.A N ASP 34.A O no hydrogen 3.469 N/A SER 39.A OG THR 36.A O no hydrogen 3.373 N/A SER 39.A OG THR 36.A OG1 no hydrogen 3.376 N/A LYS 43.A N ILE 41.A O no hydrogen 3.025 N/A LYS 52.A N ILE 48.A O no hydrogen 2.952 N/A LYS 52.A NZ ILE 384.A O no hydrogen 2.823 N/A MET 53.A N ARG 49.A O no hydrogen 2.897 N/A GLN 54.A N THR 50.A O no hydrogen 2.928 N/A GLN 55.A N ALA 51.A O no hydrogen 2.932 N/A HIS 56.A N LYS 52.A O no hydrogen 2.935 N/A VAL 57.A N MET 53.A O no hydrogen 2.943 N/A CYS 58.A N GLN 54.A O no hydrogen 2.935 N/A CYS 58.A SG GLN 54.A O no hydrogen 3.263 N/A GLU 59.A N GLN 55.A O no hydrogen 2.913 N/A THR 60.A N HIS 56.A O no hydrogen 2.947 N/A THR 60.A OG1 HIS 56.A O no hydrogen 3.185 N/A ILE 61.A N VAL 57.A O no hydrogen 2.974 N/A ILE 62.A N CYS 58.A O no hydrogen 2.902 N/A ARG 63.A N GLU 59.A O no hydrogen 2.900 N/A ILE 64.A N THR 60.A O no hydrogen 2.994 N/A PHE 65.A N ILE 61.A O no hydrogen 3.230 N/A LYS 66.A N ILE 62.A O no hydrogen 3.220 N/A ARG 67.A N ILE 64.A O no hydrogen 3.244 N/A HIS 68.A N PHE 65.A O no hydrogen 3.171 N/A HIS 68.A NE2 GLU 173.A OE1 no hydrogen 2.785 N/A GLY 69.A N LYS 66.A O no hydrogen 3.338 N/A CYS 74.A SG GLU 130.A OE2 no hydrogen 3.277 N/A ARG 81.A N LEU 101.A O no hydrogen 3.495 N/A TYR 86.A OH ASP 107.A OD1 no hydrogen 3.315 N/A PHE 94.A N VAL 102.A O no hydrogen 3.030 N/A ASP 96.A N MET 100.A O no hydrogen 3.185 N/A GLY 99.A N ASP 96.A O no hydrogen 3.273 N/A VAL 102.A N PHE 94.A O no hydrogen 2.904 N/A MET 103.A N LEU 79.A O no hydrogen 3.260 N/A LEU 104.A N ALA 92.A O no hydrogen 3.433 N/A ARG 109.A NE.A ASP 152.A OD2 no hydrogen 3.334 N/A ARG 109.A NH2.A VAL 364.A O no hydrogen 2.733 N/A PHE 112.A N LEU 108.A O no hydrogen 3.335 N/A ALA 113.A N ARG 109.A O no hydrogen 2.886 N/A ARG 114.A N ILE 110.A O no hydrogen 2.931 N/A TYR 115.A N PRO 111.A O no hydrogen 2.884 N/A VAL 116.A N PHE 112.A O no hydrogen 2.871 N/A ALA 117.A N ALA 113.A O no hydrogen 2.913 N/A ARG 118.A N ARG 114.A O no hydrogen 2.915 N/A ASN 119.A N TYR 115.A O no hydrogen 2.892 N/A ASN 119.A ND2 TYR 115.A O no hydrogen 2.786 N/A ASN 120.A ND2 ASN 120.A O no hydrogen 2.498 N/A ILE 121.A N VAL 116.A O no hydrogen 3.311 N/A LEU 124.A N VAL 154.A O no hydrogen 3.110 N/A LYS 125.A NZ GLU 166.A OE2 no hydrogen 2.983 N/A ARG 126.A N ASP 152.A O no hydrogen 3.044 N/A TYR 127.A N VAL 71.A O no hydrogen 2.904 N/A CYS 128.A N ALA 150.A O no hydrogen 3.301 N/A CYS 128.A SG LEU 73.A O no hydrogen 3.124 N/A CYS 128.A SG GLU 130.A OE2 no hydrogen 3.220 N/A GLU 130.A N GLU 148.A O no hydrogen 3.214 N/A VAL 132.A N LEU 146.A O no hydrogen 2.847 N/A ARG 134.A N LYS 144.A O no hydrogen 3.229 N/A ARG 134.A NH1 PHE 106.A O no hydrogen 3.221 N/A ARG 140.A N ASP 139.A OD1 no hydrogen 3.091 N/A HIS 142.A ND1 PRO 143.A O no hydrogen 3.079 N/A LYS 144.A N ARG 134.A O no hydrogen 2.896 N/A LEU 146.A N VAL 132.A O no hydrogen 2.951 N/A GLU 148.A N GLU 130.A O no hydrogen 3.135 N/A CYS 149.A N ILE 366.A O no hydrogen 3.222 N/A CYS 149.A SG CYS 128.A O no hydrogen 3.709 N/A CYS 149.A SG ALA 150.A O no hydrogen 4.016 N/A ALA 150.A N CYS 128.A O no hydrogen 2.893 N/A PHE 151.A N VAL 364.A O no hydrogen 3.269 N/A ASP 152.A N ARG 126.A O no hydrogen 2.951 N/A ILE 153.A N ILE 362.A O no hydrogen 2.646 N/A VAL 154.A N LEU 124.A O no hydrogen 2.924 N/A THR 155.A N THR 360.A O no hydrogen 3.263 N/A THR 155.A OG1 SER 160.A OG no hydrogen 3.087 N/A SER 156.A N ASN 123.A OD1 no hydrogen 3.247 N/A THR 157.A OG1 SER 160.A OG no hydrogen 2.692 N/A SER 160.A OG THR 155.A OG1 no hydrogen 3.087 N/A SER 160.A OG THR 157.A O no hydrogen 2.457 N/A SER 160.A OG THR 157.A OG1 no hydrogen 2.692 N/A GLU 166.A N LEU 162.A O no hydrogen 2.891 N/A ILE 167.A N PRO 163.A O no hydrogen 2.912 N/A ILE 168.A N THR 164.A O no hydrogen 2.975 N/A TYR 169.A N ALA 165.A O no hydrogen 2.851 N/A THR 170.A N GLU 166.A O no hydrogen 2.887 N/A THR 170.A OG1 GLU 166.A O no hydrogen 3.168 N/A ILE 171.A N ILE 167.A O no hydrogen 3.020 N/A TYR 172.A N ILE 168.A O no hydrogen 2.884 N/A GLU 173.A N TYR 169.A O no hydrogen 2.864 N/A ILE 174.A N THR 170.A O no hydrogen 2.988 N/A ILE 175.A N ILE 171.A O no hydrogen 2.916 N/A GLN 176.A N TYR 172.A O no hydrogen 2.884 N/A GLU 177.A N GLU 173.A O no hydrogen 2.947 N/A PHE 178.A N ILE 175.A O no hydrogen 3.437 N/A LEU 181.A N PHE 178.A O no hydrogen 3.198 N/A GLN 182.A NE2 GLN 176.A O no hydrogen 2.325 N/A SER 187.A N VAL 322.A O no hydrogen 2.924 N/A ILE 188.A N GLN 300.A O no hydrogen 3.291 N/A TYR 189.A N GLN 320.A O no hydrogen 3.092 N/A ASN 191.A N ILE 318.A O no hydrogen 3.084 N/A ASN 191.A ND2 LEU 305.A O no hydrogen 2.992 N/A ASN 191.A ND2 LEU 307.A O no hydrogen 3.455 N/A HIS 192.A N ASN 191.A OD1 no hydrogen 2.369 N/A THR 193.A N GLY 316.A O no hydrogen 3.059 N/A MET 194.A N HIS 192.A ND1 no hydrogen 3.333 N/A LEU 196.A N HIS 192.A O no hydrogen 3.291 N/A LYS 197.A N THR 193.A O no hydrogen 2.925 N/A ALA 198.A N MET 194.A O no hydrogen 2.900 N/A ILE 199.A N LEU 195.A O no hydrogen 2.892 N/A LEU 200.A N LEU 196.A O no hydrogen 2.939 N/A LEU 201.A N LYS 197.A O no hydrogen 2.902 N/A HIS 202.A N ALA 198.A O no hydrogen 2.893 N/A CYS 203.A N ILE 199.A O no hydrogen 2.916 N/A CYS 203.A SG ARG 246.A O no hydrogen 3.198 N/A GLY 204.A N LEU 201.A O no hydrogen 3.144 N/A ILE 205.A N LEU 200.A O no hydrogen 3.347 N/A LYS 209.A N PRO 206.A O no hydrogen 3.411 N/A TYR 214.A N LEU 210.A O no hydrogen 2.920 N/A ILE 215.A N SER 211.A O no hydrogen 2.927 N/A ILE 216.A N GLN 212.A O no hydrogen 2.920 N/A LEU 217.A N VAL 213.A O no hydrogen 2.908 N/A TYR 218.A N TYR 214.A O no hydrogen 2.925 N/A ASP 219.A N ILE 215.A O no hydrogen 2.899 N/A ALA 220.A N ILE 216.A O no hydrogen 2.897 N/A VAL 221.A N LEU 217.A O no hydrogen 2.906 N/A THR 222.A N TYR 218.A O no hydrogen 2.914 N/A THR 222.A OG1 TYR 218.A O no hydrogen 3.238 N/A GLU 223.A N ASP 219.A O no hydrogen 2.907 N/A LYS 224.A N ALA 220.A O no hydrogen 3.144 N/A GLU 229.A N THR 226.A OG1 no hydrogen 3.081 N/A VAL 230.A N THR 226.A O no hydrogen 2.935 N/A GLU 231.A N ARG 227.A O no hydrogen 2.928 N/A ALA 232.A N ARG 228.A O no hydrogen 2.898 N/A LYS 233.A N GLU 229.A O no hydrogen 2.883 N/A LYS 233.A NZ ASP 219.A OD2 no hydrogen 3.409 N/A PHE 234.A N VAL 230.A O no hydrogen 2.919 N/A CYS 235.A N GLU 231.A O no hydrogen 3.218 N/A ASN 236.A N ALA 232.A O no hydrogen 3.288 N/A LEU 237.A N PHE 234.A O no hydrogen 3.171 N/A SER 238.A N CYS 235.A O no hydrogen 3.231 N/A ASN 242.A N SER 240.A OG no hydrogen 2.873 N/A SER 243.A OG CYS 203.A O no hydrogen 3.309 N/A CYS 245.A N SER 241.A O no hydrogen 2.898 N/A CYS 245.A SG SER 241.A O no hydrogen 3.133 N/A CYS 245.A SG SER 241.A OG no hydrogen 2.965 N/A ARG 246.A NH2 CYS 203.A O no hydrogen 3.488 N/A LEU 247.A N LEU 244.A O no hydrogen 3.238 N/A TYR 248.A N LEU 244.A O no hydrogen 3.323 N/A LYS 249.A NZ CYS 245.A O no hydrogen 3.175 N/A LYS 254.A NZ ASN 304.A OD1 no hydrogen 2.372 N/A LEU 260.A N ASP 256.A O no hydrogen 2.994 N/A THR 263.A N LEU 260.A O no hydrogen 3.196 N/A ILE 264.A N LEU 260.A O no hydrogen 3.200 N/A ASN 265.A N MET 261.A O no hydrogen 2.976 N/A SER 266.A OG THR 263.A O no hydrogen 2.922 N/A LEU 267.A N ILE 264.A O no hydrogen 3.065 N/A ILE 268.A N ASN 265.A O no hydrogen 3.169 N/A LEU 277.A N GLY 273.A O no hydrogen 3.262 N/A VAL 278.A N ILE 274.A O no hydrogen 2.911 N/A LYS 279.A N ALA 275.A O no hydrogen 2.928 N/A GLY 281.A N LEU 277.A O no hydrogen 2.918 N/A LEU 282.A N VAL 278.A O no hydrogen 2.888 N/A LEU 282.A N LYS 279.A O no hydrogen 3.300 N/A LYS 283.A N LYS 279.A O no hydrogen 2.965 N/A GLU 286.A N LEU 282.A O no hydrogen 2.947 N/A GLU 287.A N LYS 283.A O no hydrogen 2.946 N/A VAL 288.A N ASP 284.A O no hydrogen 2.894 N/A VAL 289.A N LEU 285.A O no hydrogen 2.954 N/A GLY 290.A N GLU 286.A O no hydrogen 2.944 N/A LEU 291.A N GLU 287.A O no hydrogen 2.940 N/A LEU 292.A N VAL 288.A O no hydrogen 2.898 N/A LYS 293.A N VAL 289.A O no hydrogen 2.921 N/A LYS 294.A N GLY 290.A O no hydrogen 2.936 N/A LEU 295.A N LEU 291.A O no hydrogen 3.238 N/A GLY 296.A N LYS 293.A O no hydrogen 3.294 N/A LEU 302.A N ILE 188.A O no hydrogen 2.909 N/A ILE 303.A N GLY 255.A O no hydrogen 3.249 N/A ASN 304.A N LEU 190.A O no hydrogen 2.638 N/A GLN 313.A N LYS 310.A O no hydrogen 2.912 N/A ASN 315.A N ARG 341.A O no hydrogen 3.118 N/A ASN 315.A ND2 ASP 343.A OD1 no hydrogen 2.379 N/A GLY 316.A N THR 193.A OG1 no hydrogen 3.025 N/A ILE 318.A N ASN 191.A O no hydrogen 3.058 N/A PHE 319.A N GLY 339.A O no hydrogen 3.271 N/A GLN 320.A N TYR 189.A O no hydrogen 3.215 N/A PHE 321.A N ALA 337.A O no hydrogen 3.067 N/A VAL 322.A N SER 187.A O no hydrogen 3.129 N/A ALA 323.A N GLU 334.A O no hydrogen 3.428 N/A ARG 327.A N ARG 330.A O no hydrogen 3.170 N/A ARG 330.A N ARG 327.A O no hydrogen 3.132 N/A VAL 332.A N ILE 325.A O no hydrogen 3.373 N/A GLU 334.A N ALA 323.A O no hydrogen 3.174 N/A LEU 336.A N PHE 321.A O no hydrogen 3.267 N/A GLY 339.A N PHE 319.A O no hydrogen 3.374 N/A GLY 340.A N GLY 363.A O no hydrogen 3.333 N/A TYR 342.A N ALA 361.A O no hydrogen 3.142 N/A LEU 344.A N ASN 315.A OD1 no hydrogen 3.323 N/A LEU 345.A N TYR 342.A O no hydrogen 3.376 N/A PHE 349.A N ILE 346.A O no hydrogen 3.116 N/A ARG 350.A NH1 GLY 356.A O no hydrogen 3.186 N/A ALA 354.A N GLY 351.A O no hydrogen 3.100 N/A THR 360.A OG1 THR 155.A O no hydrogen 3.563 N/A ILE 362.A N ILE 153.A O no hydrogen 2.787 N/A GLY 363.A N GLY 340.A O no hydrogen 3.394 N/A VAL 364.A N PHE 151.A O no hydrogen 3.028 N/A SER 365.A N ALA 338.A O no hydrogen 3.222 N/A ILE 366.A N CYS 149.A O no hydrogen 3.047 N/A ALA 367.A N LEU 336.A O no hydrogen 3.454 N/A SER 372.A N ILE 368.A O no hydrogen 2.940 N/A SER 372.A OG ILE 368.A O no hydrogen 3.244 N/A ALA 373.A N ASP 369.A O no hydrogen 2.909 N/A ALA 374.A N LYS 370.A O no hydrogen 2.904 N/A VAL 375.A N ILE 371.A O no hydrogen 2.919 N/A LEU 376.A N SER 372.A O no hydrogen 2.921 N/A ASN 377.A N ALA 373.A O no hydrogen 3.197 N/A MET 378.A N VAL 375.A O no hydrogen 3.198 N/A GLU 380.A N GLU 380.A OE1 no hydrogen 2.636 N/A SER 381.A N GLU 379.A O no hydrogen 2.893 N/A CYS 387.A SG LEU 389.A O no hydrogen 3.963 N/A ASP 388.A N THR 415.A O no hydrogen 3.373 N/A LEU 390.A N TYR 440.A O no hydrogen 3.014 N/A VAL 391.A N GLU 417.A O no hydrogen 2.959 N/A VAL 392.A N ALA 442.A O no hydrogen 2.968 N/A SER 393.A OG GLY 395.A O no hydrogen 3.441 N/A SER 393.A OG SER 398.A OG no hydrogen 2.340 N/A VAL 394.A N VAL 444.A O no hydrogen 3.108 N/A SER 398.A OG SER 393.A OG no hydrogen 2.340 N/A SER 398.A OG VAL 394.A O no hydrogen 2.477 N/A SER 398.A OG GLY 395.A O no hydrogen 3.130 N/A ARG 401.A NE GLU 469.A OE1 no hydrogen 3.243 N/A ARG 401.A NH1 SER 445.A O no hydrogen 2.412 N/A ARG 401.A NH2 HIS 451.A O no hydrogen 3.524 N/A ARG 401.A NH2 GLU 469.A OE1 no hydrogen 3.369 N/A ALA 402.A N SER 398.A O no hydrogen 3.083 N/A ILE 403.A N MET 399.A O no hydrogen 2.900 N/A ASN 404.A N SER 400.A O no hydrogen 2.944 N/A LEU 405.A N ARG 401.A O no hydrogen 2.912 N/A THR 406.A N ALA 402.A O no hydrogen 2.901 N/A THR 406.A OG1 ALA 402.A O no hydrogen 3.051 N/A GLN 407.A N ILE 403.A O no hydrogen 2.924 N/A LYS 408.A N ASN 404.A O no hydrogen 2.918 N/A LEU 409.A N LEU 405.A O no hydrogen 2.908 N/A TRP 410.A N THR 406.A O no hydrogen 2.894 N/A TRP 410.A NE1 ALA 416.A O no hydrogen 2.555 N/A THR 411.A N GLN 407.A O no hydrogen 2.941 N/A THR 411.A OG1 GLN 407.A O no hydrogen 2.772 N/A ALA 412.A N LYS 408.A O no hydrogen 3.223 N/A ALA 412.A N LEU 409.A O no hydrogen 3.167 N/A GLY 413.A N TRP 410.A O no hydrogen 3.062 N/A ILE 414.A N LEU 409.A O no hydrogen 3.347 N/A THR 415.A OG1 ASP 388.A OD2 no hydrogen 3.541 N/A GLU 417.A N LEU 389.A O no hydrogen 3.226 N/A MET 419.A N VAL 391.A O no hydrogen 3.021 N/A SER 425.A N GLU 428.A OE1 no hydrogen 3.178 N/A LEU 429.A N SER 425.A O no hydrogen 3.025 N/A GLN 430.A N GLN 426.A O no hydrogen 2.915 N/A GLU 431.A N GLU 427.A O no hydrogen 2.926 N/A TYR 432.A N GLU 428.A O no hydrogen 2.891 N/A CYS 433.A N LEU 429.A O no hydrogen 2.907 N/A CYS 433.A SG LEU 429.A O no hydrogen 3.254 N/A ARG 434.A N GLN 430.A O no hydrogen 2.916 N/A HIS 435.A N GLU 431.A O no hydrogen 2.914 N/A HIS 436.A N TYR 432.A O no hydrogen 3.147 N/A GLU 437.A N ARG 434.A O no hydrogen 3.400 N/A ILE 438.A N CYS 433.A O no hydrogen 2.998 N/A VAL 441.A N LYS 455.A O no hydrogen 3.195 N/A ALA 442.A N LEU 390.A O no hydrogen 2.848 N/A LEU 443.A N LYS 453.A O no hydrogen 3.101 N/A VAL 444.A N VAL 392.A O no hydrogen 2.996 N/A LYS 447.A N SER 445.A OG no hydrogen 3.164 N/A HIS 451.A N GLU 448.A O no hydrogen 3.214 N/A HIS 451.A ND1 GLU 448.A O no hydrogen 3.164 N/A VAL 452.A N VAL 467.A O no hydrogen 2.943 N/A VAL 454.A N LYS 465.A O no hydrogen 2.963 N/A LYS 455.A N VAL 441.A O no hydrogen 2.965 N/A LYS 455.A NZ GLN 426.A OE1 no hydrogen 2.769 N/A SER 456.A N THR 463.A O no hydrogen 3.229 N/A PHE 457.A N THR 439.A O no hydrogen 3.132 N/A ARG 461.A N GLU 458.A O no hydrogen 3.224 N/A LYS 465.A N VAL 454.A O no hydrogen 3.246 N/A VAL 467.A N VAL 452.A O no hydrogen 3.073 N/A GLU 469.A N SER 450.A O no hydrogen 3.103 N/A GLU 471.A N LEU 468.A O no hydrogen 3.167 N/A LEU 472.A N GLU 469.A O no hydrogen 3.314 N/A HIS 475.A N GLU 471.A O no hydrogen 3.027 N/A VAL 476.A N LEU 472.A O no hydrogen 2.913 N/A LEU 477.A N VAL 473.A O no hydrogen 2.919 N/A GLN 478.A N ASP 474.A O no hydrogen 2.883 N/A LYS 479.A N HIS 475.A O no hydrogen 2.910 N/A LEU 480.A N VAL 476.A O no hydrogen 2.907 N/A ARG 481.A N LEU 477.A O no hydrogen 2.905 N/A THR 482.A N GLN 478.A O no hydrogen 2.899 N/A LYS 483.A N LYS 479.A O no hydrogen 3.474 N/A