Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8tk0_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): MET 1.A N ASP 76.A O no hydrogen 3.523 N/A LYS 2.A NZ PHE 3.A O no hydrogen 3.497 N/A LYS 2.A NZ ASP 22.A OD1 no hydrogen 3.444 N/A SER 4.A N THR 74.A O no hydrogen 2.946 N/A ASN 5.A ND2 ASN 18.A OD1 no hydrogen 2.714 N/A ILE 6.A N ILE 19.A O no hydrogen 2.921 N/A THR 7.A N ILE 72.A O no hydrogen 3.185 N/A ILE 8.A N VAL 17.A O no hydrogen 2.924 N/A LYS 9.A N GLU 70.A O no hydrogen 3.196 N/A ASN 10.A N GLU 15.A O no hydrogen 3.380 N/A ASN 10.A ND2 LYS 68.A O no hydrogen 3.371 N/A PHE 11.A N PHE 14.A O no hydrogen 3.250 N/A ARG 12.A N ASP 59.A O no hydrogen 3.341 N/A ARG 12.A NH1 ASN 37.A OD1 no hydrogen 3.039 N/A ARG 12.A NH2 ASP 59.A OD2 no hydrogen 3.199 N/A PHE 14.A N PHE 11.A O no hydrogen 2.949 N/A VAL 17.A N ILE 8.A O no hydrogen 2.964 N/A ILE 19.A N ILE 6.A O no hydrogen 2.959 N/A LEU 21.A N SER 4.A O no hydrogen 3.494 N/A ASP 22.A N ASN 25.A OD1 no hydrogen 2.913 N/A LYS 24.A NZ LEU 185.A O no hydrogen 3.556 N/A LYS 24.A NZ TYR 191.A O no hydrogen 3.428 N/A ASN 25.A ND2 ASP 22.A O no hydrogen 2.823 N/A ASN 25.A ND2 PHE 194.A O no hydrogen 3.623 N/A VAL 26.A N ARG 211.A O no hydrogen 2.924 N/A ILE 27.A N LEU 196.A O no hydrogen 2.922 N/A PHE 28.A N ILE 213.A O no hydrogen 2.965 N/A THR 36.A N ASP 32.A O no hydrogen 2.935 N/A THR 36.A OG1 ASP 32.A O no hydrogen 2.990 N/A ASN 37.A N ILE 33.A O no hydrogen 2.932 N/A PHE 38.A N GLY 34.A O no hydrogen 2.915 N/A ALA 41.A N ASN 37.A O no hydrogen 2.970 N/A ARG 43.A N LEU 39.A O no hydrogen 2.957 N/A PHE 44.A N TYR 40.A O no hydrogen 2.918 N/A LEU 45.A N LEU 42.A O no hydrogen 3.096 N/A LEU 46.A N LEU 42.A O no hydrogen 2.995 N/A ASP 47.A N ARG 43.A O no hydrogen 3.045 N/A SER 58.A OG ASP 59.A OD1 no hydrogen 3.198 N/A LYS 62.A N HIS 61.A ND1 no hydrogen 2.861 N/A HIS 63.A N HIS 61.A O no hydrogen 2.300 N/A THR 65.A OG1 THR 65.A O no hydrogen 2.505 N/A SER 66.A N ASP 64.A O no hydrogen 2.860 N/A SER 66.A OG ASP 64.A OD2 no hydrogen 3.111 N/A LYS 67.A NZ ASP 64.A OD2 no hydrogen 2.817 N/A GLU 70.A N LYS 9.A O no hydrogen 3.419 N/A ILE 71.A N LEU 109.A O no hydrogen 2.988 N/A ILE 72.A N THR 7.A O no hydrogen 3.292 N/A LEU 73.A N ILE 107.A O no hydrogen 2.856 N/A THR 74.A N ASN 5.A O no hydrogen 3.272 N/A LEU 75.A N PHE 105.A O no hydrogen 3.309 N/A ASP 76.A N LYS 2.A O no hydrogen 2.940 N/A LEU 77.A N ASP 103.A O no hydrogen 2.638 N/A ASP 85.A N ASP 83.A OD1 no hydrogen 2.285 N/A THR 86.A N ASP 83.A OD1 no hydrogen 3.041 N/A THR 86.A OG1 ASN 79.A O no hydrogen 3.221 N/A LYS 88.A N ASP 85.A O no hydrogen 3.262 N/A ILE 90.A N LYS 87.A O no hydrogen 3.089 N/A SER 91.A N LYS 87.A O no hydrogen 2.822 N/A SER 91.A OG LYS 87.A O no hydrogen 3.363 N/A LYS 94.A NZ VAL 92.A O no hydrogen 3.320 N/A PHE 105.A N LEU 75.A O no hydrogen 2.972 N/A TYR 106.A N GLY 127.A O no hydrogen 2.987 N/A ILE 107.A N LEU 73.A O no hydrogen 2.990 N/A ALA 108.A N LYS 125.A O no hydrogen 2.870 N/A LEU 109.A N ILE 71.A O no hydrogen 2.886 N/A GLU 110.A N ILE 123.A O no hydrogen 2.940 N/A ASP 114.A N TYR 119.A O no hydrogen 3.300 N/A GLU 117.A N ASP 114.A OD2 no hydrogen 3.036 N/A ILE 123.A N GLU 110.A O no hydrogen 2.903 N/A LYS 125.A N ALA 108.A O no hydrogen 3.204 N/A SER 128.A OG VAL 104.A O no hydrogen 3.222 N/A ILE 134.A N TRP 126.A O no hydrogen 3.183 N/A ASN 147.A N ALA 144.A O no hydrogen 3.406 N/A VAL 148.A N LEU 145.A O no hydrogen 3.247 N/A LYS 150.A N ILE 161.A O no hydrogen 2.890 N/A ILE 152.A N ILE 163.A O no hydrogen 2.922 N/A TYR 153.A OH GLU 167.A OE1 no hydrogen 2.263 N/A ILE 154.A N LEU 165.A O no hydrogen 2.909 N/A LEU 157.A N ASN 155.A OD1 no hydrogen 3.044 N/A ILE 161.A N VAL 148.A O no hydrogen 3.071 N/A ILE 163.A N LYS 150.A O no hydrogen 2.915 N/A TYR 164.A N TYR 193.A O no hydrogen 3.300 N/A LEU 165.A N ILE 152.A O no hydrogen 2.921 N/A ILE 166.A N PHE 195.A O no hydrogen 3.171 N/A GLU 167.A N ILE 154.A O no hydrogen 2.983 N/A GLU 168.A N SER 197.A O no hydrogen 3.335 N/A GLN 178.A N HIS 174.A O no hydrogen 3.124 N/A ILE 179.A N ARG 175.A O no hydrogen 3.085 N/A ALA 180.A N SER 176.A O no hydrogen 2.969 N/A LEU 181.A N MET 177.A O no hydrogen 2.918 N/A SER 182.A N GLN 178.A O no hydrogen 2.987 N/A SER 182.A OG LEU 203.A O no hydrogen 2.272 N/A SER 182.A OG GLU 206.A OE2 no hydrogen 3.029 N/A LYS 183.A N ILE 179.A O no hydrogen 3.009 N/A GLN 184.A N ALA 180.A O no hydrogen 2.999 N/A LEU 185.A N LEU 181.A O no hydrogen 2.973 N/A PHE 186.A N SER 182.A O no hydrogen 3.004 N/A GLU 187.A N LYS 183.A O no hydrogen 2.946 N/A SER 189.A OG SER 189.A O no hydrogen 2.536 N/A PHE 194.A N ASN 23.A O no hydrogen 3.420 N/A PHE 195.A N TYR 164.A O no hydrogen 3.252 N/A LEU 196.A N ASN 25.A O no hydrogen 3.301 N/A THR 198.A OG1 GLU 170.A OE1 no hydrogen 2.899 N/A THR 198.A OG1 SER 200.A O no hydrogen 3.381 N/A HIS 199.A N GLU 170.A OE1 no hydrogen 2.911 N/A SER 200.A N THR 198.A OG1 no hydrogen 3.200 N/A SER 200.A OG GLN 178.A OE1 no hydrogen 3.068 N/A THR 210.A N TYR 228.A O no hydrogen 2.999 N/A ARG 211.A N LYS 24.A O no hydrogen 2.909 N/A ARG 211.A NH1 SER 225.A OG no hydrogen 3.147 N/A LEU 212.A N HIS 226.A O no hydrogen 2.886 N/A ILE 213.A N VAL 26.A O no hydrogen 2.879 N/A ARG 214.A N SER 224.A O no hydrogen 2.876 N/A ARG 214.A NH1 LEU 302.A O no hydrogen 3.111 N/A VAL 215.A N PHE 28.A O no hydrogen 2.930 N/A THR 218.A OG1 GLU 219.A O no hydrogen 3.527 N/A CYS 223.A SG VAL 222.A O no hydrogen 3.122 N/A SER 224.A N ARG 214.A O no hydrogen 2.994 N/A HIS 226.A N LEU 212.A O no hydrogen 2.954 N/A HIS 226.A ND1 ASP 301.A OD2 no hydrogen 2.543 N/A TYR 228.A N THR 210.A O no hydrogen 2.879 N/A TYR 228.A OH ASN 242.A OD1 no hydrogen 3.238 N/A TYR 228.A OH HIS 294.A NE2 no hydrogen 2.934 N/A LYS 238.A NZ ASP 208.A OD1 no hydrogen 3.500 N/A LEU 241.A N VAL 237.A O no hydrogen 3.286 N/A ASN 242.A N LYS 238.A O no hydrogen 2.980 N/A LYS 243.A N LYS 239.A O no hydrogen 2.930 N/A ALA 244.A N LYS 240.A O no hydrogen 2.935 N/A LEU 245.A N LEU 241.A O no hydrogen 2.972 N/A SER 246.A N ASN 242.A O no hydrogen 2.912 N/A SER 246.A OG ASN 242.A O no hydrogen 3.326 N/A SER 246.A OG LYS 243.A O no hydrogen 3.332 N/A LEU 249.A N LEU 245.A O no hydrogen 3.028 N/A PHE 250.A N SER 247.A O no hydrogen 3.336 N/A ALA 251.A N ALA 248.A O no hydrogen 3.253 N/A ARG 253.A NH2 ASN 280.A O no hydrogen 3.239 N/A VAL 254.A N THR 305.A O no hydrogen 3.328 N/A LEU 255.A N PHE 283.A O no hydrogen 3.300 N/A LEU 256.A N ILE 307.A O no hydrogen 3.035 N/A ILE 257.A N LEU 285.A O no hydrogen 2.975 N/A LYS 263.A N PRO 260.A O no hydrogen 3.455 N/A LYS 263.A NZ GLU 286.A OE2 no hydrogen 3.216 N/A GLU 267.A N LYS 263.A O no hydrogen 2.918 N/A LYS 268.A N ILE 264.A O no hydrogen 2.961 N/A LYS 268.A NZ GLU 272.A OE2 no hydrogen 2.923 N/A VAL 269.A N LEU 265.A O no hydrogen 2.951 N/A LEU 270.A N PHE 266.A O no hydrogen 2.898 N/A ASP 271.A N GLU 267.A O no hydrogen 2.894 N/A GLU 272.A N LYS 268.A O no hydrogen 2.940 N/A VAL 273.A N VAL 269.A O no hydrogen 2.919 N/A GLU 274.A N LEU 270.A O no hydrogen 2.792 N/A GLU 276.A N GLU 276.A OE1 no hydrogen 2.613 N/A LEU 285.A N LEU 255.A O no hydrogen 2.933 N/A VAL 287.A N ILE 257.A O no hydrogen 3.268 N/A HIS 294.A NE2 TYR 228.A OH no hydrogen 2.934 N/A VAL 296.A N PHE 292.A O no hydrogen 3.057 N/A CYS 297.A N ASN 293.A O no hydrogen 2.993 N/A CYS 297.A SG ASN 293.A O no hydrogen 3.713 N/A THR 298.A OG1 HIS 294.A O no hydrogen 2.929 N/A LEU 299.A N TYR 295.A O no hydrogen 2.952 N/A ASN 300.A N VAL 296.A O no hydrogen 2.884 N/A ASP 301.A N CYS 297.A O no hydrogen 2.981 N/A GLY 303.A N ASN 300.A O no hydrogen 3.405 N/A ILE 304.A N LEU 299.A O no hydrogen 3.047 N/A ILE 307.A N VAL 254.A O no hydrogen 3.165 N/A ILE 308.A N ARG 383.A O no hydrogen 3.276 N/A THR 310.A N TYR 385.A O no hydrogen 2.903 N/A THR 310.A OG1 ASP 311.A O no hydrogen 3.497 N/A ASN 312.A N SER 387.A O no hydrogen 3.388 N/A LYS 321.A NZ GLY 319.A O no hydrogen 2.739 N/A TYR 324.A N ILE 344.A O no hydrogen 3.022 N/A GLU 325.A N LYS 315.A O no hydrogen 2.940 N/A ARG 331.A N LEU 327.A O no hydrogen 2.895 N/A ARG 331.A NH1 THR 290.A O no hydrogen 3.239 N/A CYS 332.A N GLY 328.A O no hydrogen 2.930 N/A CYS 332.A SG GLY 328.A O no hydrogen 3.499 N/A LEU 333.A N LEU 329.A O no hydrogen 2.905 N/A ASN 334.A N ASN 330.A O no hydrogen 2.904 N/A LEU 335.A N CYS 332.A O no hydrogen 3.391 N/A LEU 336.A N LEU 333.A O no hydrogen 3.104 N/A LEU 341.A N ASN 330.A OD1 no hydrogen 3.361 N/A GLU 343.A N GLU 343.A OE1 no hydrogen 2.716 N/A ILE 344.A N TYR 324.A O no hydrogen 3.221 N/A ILE 346.A N GLY 322.A O no hydrogen 3.011 N/A LYS 355.A NZ ASP 411.A OD2 no hydrogen 3.528 N/A GLU 359.A N LYS 355.A O no hydrogen 2.906 N/A ARG 360.A N LYS 356.A O no hydrogen 2.940 N/A LEU 361.A N LYS 357.A O no hydrogen 2.940 N/A ASN 362.A N LYS 358.A O no hydrogen 2.901 N/A GLU 363.A N GLU 359.A O no hydrogen 2.923 N/A ARG 364.A N ARG 360.A O no hydrogen 2.967 N/A LYS 365.A N LEU 361.A O no hydrogen 2.909 N/A LYS 366.A N ASN 362.A O no hydrogen 2.899 N/A GLU 367.A N GLU 363.A O no hydrogen 2.960 N/A ILE 368.A N ARG 364.A O no hydrogen 2.936 N/A PHE 369.A N LYS 365.A O no hydrogen 2.898 N/A LYS 370.A N LYS 366.A O no hydrogen 2.899 N/A GLN 371.A N GLU 367.A O no hydrogen 2.965 N/A GLN 371.A N ILE 368.A O no hydrogen 3.167 N/A TYR 372.A N PHE 369.A O no hydrogen 3.330 N/A LYS 373.A NZ LYS 370.A O no hydrogen 2.502 N/A VAL 376.A N TYR 372.A O no hydrogen 2.980 N/A GLY 377.A N LYS 373.A O no hydrogen 2.902 N/A GLU 378.A N ASN 374.A O no hydrogen 2.938 N/A PHE 379.A N GLU 375.A O no hydrogen 2.887 N/A LEU 380.A N VAL 376.A O no hydrogen 2.976 N/A GLU 382.A N PHE 379.A O no hydrogen 3.275 N/A TYR 385.A N ILE 308.A O no hydrogen 2.928 N/A SER 387.A N THR 310.A O no hydrogen 2.941 N/A GLU 388.A N GLU 388.A OE1 no hydrogen 2.718 N/A LEU 391.A N ASP 390.A OD1 no hydrogen 2.681 N/A GLU 392.A N GLU 392.A OE1 no hydrogen 2.542 N/A LEU 395.A N LEU 391.A O no hydrogen 2.921 N/A TYR 396.A N GLU 392.A O no hydrogen 2.868 N/A SER 397.A N ASN 393.A O no hydrogen 2.921 N/A ALA 398.A N ASP 394.A O no hydrogen 2.936 N/A ALA 398.A N LEU 395.A O no hydrogen 3.219 N/A ILE 399.A N LEU 395.A O no hydrogen 2.939 N/A GLU 401.A N GLU 401.A OE1 no hydrogen 2.589 N/A SER 402.A OG ASP 435.A OD1 no hydrogen 3.020 N/A MET 403.A N ILE 399.A O no hydrogen 2.905 N/A LYS 404.A N GLY 400.A O no hydrogen 2.934 N/A HIS 414.A N ASP 411.A O no hydrogen 3.028 N/A LEU 416.A N PRO 412.A O no hydrogen 2.925 N/A GLN 417.A N VAL 413.A O no hydrogen 2.936 N/A LYS 418.A N HIS 414.A O no hydrogen 2.949 N/A MET 424.A N LYS 420.A O no hydrogen 3.001 N/A VAL 425.A N LEU 421.A O no hydrogen 2.963 N/A GLU 426.A N PHE 422.A O no hydrogen 2.935 N/A LEU 427.A N ASN 423.A O no hydrogen 2.864 N/A VAL 428.A N MET 424.A O no hydrogen 2.902 N/A ASN 429.A N VAL 425.A O no hydrogen 2.977 N/A ASN 430.A N GLU 426.A O no hydrogen 3.383 N/A SER 432.A OG ASP 435.A OD2 no hydrogen 3.365 N/A THR 433.A OG1 GLU 272.A OE1 no hydrogen 3.198 N/A LYS 434.A NZ ASP 438.A OD1 no hydrogen 2.714 N/A LYS 434.A NZ ASP 438.A OD2 no hydrogen 3.093 N/A CYS 436.A N SER 432.A O no hydrogen 3.381 N/A CYS 436.A SG SER 432.A O no hydrogen 3.492 N/A PHE 437.A N THR 433.A O no hydrogen 2.964 N/A ASP 438.A N LYS 434.A O no hydrogen 2.906 N/A VAL 439.A N ASP 435.A O no hydrogen 2.940 N/A PHE 440.A N CYS 436.A O no hydrogen 3.135 N/A LYS 444.A N HIS 442.A ND1 no hydrogen 3.239 N/A LYS 444.A NZ GLU 388.A OE1 no hydrogen 3.255 N/A LYS 444.A NZ ASP 394.A OD1 no hydrogen 2.374 N/A PHE 445.A N HIS 442.A O no hydrogen 3.397 N/A ALA 446.A N GLU 443.A O no hydrogen 3.305 N/A LYS 449.A N ALA 446.A O no hydrogen 2.938 N/A GLU 450.A N CYS 447.A O no hydrogen 2.924 N/A LEU 451.A N CYS 447.A O no hydrogen 3.329 N/A LEU 451.A N LEU 448.A O no hydrogen 2.933 N/A VAL 452.A N LEU 448.A O no hydrogen 3.345 N/A