Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8tlq_F.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LEU 6.A N HIS 2.A O no hydrogen 3.162 N/A LEU 7.A N MET 3.A O no hydrogen 2.902 N/A THR 8.A N ASP 4.A O no hydrogen 2.902 N/A LYS 9.A N ALA 5.A O no hydrogen 2.903 N/A PHE 10.A N LEU 6.A O no hydrogen 2.925 N/A ASN 11.A N LEU 7.A O no hydrogen 2.887 N/A ARG 27.A NE SER 285.A O no hydrogen 3.168 N/A ARG 27.A NH1 LEU 232.A O no hydrogen 3.077 N/A ARG 27.A NH1 ILE 243.A O no hydrogen 3.210 N/A ARG 27.A NH2 LEU 232.A O no hydrogen 3.350 N/A ARG 27.A NH2 SER 285.A O no hydrogen 2.726 N/A VAL 28.A N SER 244.A O no hydrogen 3.249 N/A ASP 33.A N SER 338.A O no hydrogen 3.241 N/A ASN 34.A N ASP 32.A OD1 no hydrogen 3.432 N/A ASN 34.A ND2 GLU 336.A O no hydrogen 2.374 N/A LEU 35.A N ASP 32.A O no hydrogen 3.151 N/A SER 39.A OG LYS 38.A O no hydrogen 2.640 N/A GLN 43.A N ASN 40.A O no hydrogen 3.221 N/A ARG 49.A N CYS 45.A O no hydrogen 3.496 N/A TYR 59.A N TYR 55.A O no hydrogen 2.937 N/A GLN 60.A N TYR 56.A O no hydrogen 2.864 N/A TYR 61.A N HIS 57.A O no hydrogen 2.927 N/A ARG 62.A N ILE 58.A O no hydrogen 2.905 N/A ARG 62.A NH1 ALA 383.A O no hydrogen 3.515 N/A LEU 63.A N TYR 59.A O no hydrogen 2.893 N/A LYS 64.A N GLN 60.A O no hydrogen 2.880 N/A THR 65.A N TYR 61.A O no hydrogen 2.939 N/A THR 65.A OG1 TYR 61.A O no hydrogen 2.780 N/A THR 65.A OG1 ARG 62.A O no hydrogen 2.728 N/A PHE 66.A N ARG 62.A O no hydrogen 2.923 N/A ARG 67.A N LEU 63.A O no hydrogen 2.872 N/A GLU 68.A N LYS 64.A O no hydrogen 2.908 N/A ARG 69.A N THR 65.A O no hydrogen 2.937 N/A ARG 69.A NH1 LEU 399.A O no hydrogen 3.130 N/A VAL 70.A N PHE 66.A O no hydrogen 2.906 N/A LEU 71.A N ARG 67.A O no hydrogen 2.882 N/A LYS 72.A N GLU 68.A O no hydrogen 2.917 N/A GLU 73.A N ARG 69.A O no hydrogen 2.941 N/A CYS 74.A N VAL 70.A O no hydrogen 2.872 N/A CYS 74.A SG VAL 70.A O no hydrogen 3.483 N/A ASP 75.A N LEU 71.A O no hydrogen 2.898 N/A LYS 76.A N LYS 72.A O no hydrogen 2.913 N/A ARG 77.A N GLU 73.A O no hydrogen 2.903 N/A TRP 78.A N CYS 74.A O no hydrogen 2.537 N/A PHE 82.A N ASP 79.A O no hydrogen 3.299 N/A LEU 84.A N GLN 87.A O no hydrogen 2.841 N/A VAL 89.A N PHE 82.A O no hydrogen 3.383 N/A LEU 90.A N PRO 103.A O no hydrogen 3.130 N/A LYS 92.A N LEU 90.A O no hydrogen 2.962 N/A ASP 97.A N LYS 94.A O no hydrogen 3.248 N/A GLN 99.A N ASP 97.A O no hydrogen 3.100 N/A CYS 104.A N GLY 177.A O no hydrogen 2.994 N/A CYS 104.A SG GLN 102.A O no hydrogen 3.332 N/A CYS 104.A SG GLY 177.A O no hydrogen 3.751 N/A TRP 105.A N LEU 90.A O no hydrogen 3.241 N/A CYS 106.A N ILE 175.A O no hydrogen 3.046 N/A SER 109.A N GLU 149.A O no hydrogen 2.430 N/A SER 109.A OG GLU 149.A O no hydrogen 3.559 N/A ILE 110.A N VAL 171.A O no hydrogen 3.184 N/A TYR 111.A N MET 147.A O no hydrogen 2.586 N/A CYS 112.A SG TYR 111.A O no hydrogen 3.241 N/A TYR 116.A N TYR 138.A OH no hydrogen 2.782 N/A TYR 116.A OH ASP 388.A OD1 no hydrogen 3.155 N/A LEU 121.A N LYS 117.A O no hydrogen 3.119 N/A ASP 122.A N PRO 118.A O no hydrogen 2.906 N/A GLU 123.A N ASN 119.A O no hydrogen 2.902 N/A VAL 124.A N VAL 120.A O no hydrogen 2.916 N/A ILE 125.A N LEU 121.A O no hydrogen 2.905 N/A ASN 126.A N ASP 122.A O no hydrogen 3.216 N/A ASN 126.A ND2 ASP 122.A O no hydrogen 2.480 N/A ASP 127.A N VAL 124.A O no hydrogen 3.381 N/A THR 135.A OG1 ASP 133.A OD1 no hydrogen 2.982 N/A LYS 136.A N ASP 133.A OD1 no hydrogen 3.236 N/A SER 137.A N ASP 133.A O no hydrogen 2.947 N/A TYR 138.A N LEU 134.A O no hydrogen 2.897 N/A THR 139.A N THR 135.A O no hydrogen 2.906 N/A MET 147.A N TYR 111.A O no hydrogen 3.231 N/A LEU 148.A N VAL 155.A O no hydrogen 3.307 N/A GLU 149.A N SER 109.A O no hydrogen 2.770 N/A VAL 155.A N LEU 148.A O no hydrogen 3.415 N/A LEU 157.A N ILE 146.A O no hydrogen 3.241 N/A VAL 158.A N PHE 185.A O no hydrogen 3.016 N/A ARG 163.A N GLY 159.A O no hydrogen 3.295 N/A SER 164.A N ASP 160.A O no hydrogen 3.495 N/A THR 165.A OG1 SER 164.A O no hydrogen 2.681 N/A VAL 173.A N GLY 108.A O no hydrogen 3.469 N/A GLY 174.A N CYS 191.A O no hydrogen 3.066 N/A ILE 175.A N CYS 106.A O no hydrogen 3.083 N/A LEU 176.A N ASP 189.A O no hydrogen 2.977 N/A GLY 177.A N CYS 104.A O no hydrogen 3.041 N/A ALA 180.A N THR 184.A O no hydrogen 2.860 N/A THR 184.A N ALA 182.A O no hydrogen 2.769 N/A PHE 185.A N LEU 156.A O no hydrogen 2.532 N/A GLN 186.A N MET 178.A O no hydrogen 2.990 N/A VAL 187.A N VAL 158.A O no hydrogen 2.763 N/A LEU 188.A N LEU 176.A O no hydrogen 2.757 N/A ASP 189.A N LEU 176.A O no hydrogen 3.324 N/A ILE 190.A N ASP 189.A OD1 no hydrogen 3.151 N/A GLN 198.A NE2 TRP 402.A O no hydrogen 2.851 N/A LYS 205.A N LEU 245.A O no hydrogen 2.744 N/A LYS 205.A NZ ASP 242.A OD1 no hydrogen 3.382 N/A ILE 206.A N LEU 443.A O no hydrogen 2.964 N/A ALA 207.A N ARG 248.A O no hydrogen 3.269 N/A LEU 208.A N ILE 441.A O no hydrogen 2.882 N/A VAL 209.A N LEU 250.A O no hydrogen 3.232 N/A SER 210.A OG PRO 432.A O no hydrogen 3.139 N/A GLY 211.A N GLY 253.A O no hydrogen 3.241 N/A ASN 213.A N ASN 254.A O no hydrogen 2.732 N/A ASN 213.A ND2 SER 435.A OG no hydrogen 3.004 N/A LEU 214.A N SER 255.A O no hydrogen 2.668 N/A ASN 215.A ND2 ASN 213.A O no hydrogen 2.615 N/A THR 217.A N ASN 215.A OD1 no hydrogen 2.813 N/A SER 218.A N ASN 215.A OD1 no hydrogen 2.836 N/A ARG 221.A NH1 ASN 213.A O no hydrogen 3.063 N/A LEU 223.A N PRO 219.A O no hydrogen 3.302 N/A ARG 224.A N ASP 220.A O no hydrogen 2.914 N/A LEU 225.A N ARG 221.A O no hydrogen 2.887 N/A GLU 226.A N LEU 222.A O no hydrogen 2.898 N/A ILE 227.A N LEU 223.A O no hydrogen 2.920 N/A LEU 228.A N ARG 224.A O no hydrogen 2.897 N/A ARG 229.A N LEU 225.A O no hydrogen 2.886 N/A ARG 229.A NH1 ASN 281.A O no hydrogen 3.427 N/A GLU 230.A N GLU 226.A O no hydrogen 2.911 N/A PHE 231.A N ILE 227.A O no hydrogen 2.894 N/A LEU 232.A N LEU 228.A O no hydrogen 2.898 N/A MET 233.A N GLU 230.A O no hydrogen 3.302 N/A GLY 234.A N PHE 231.A O no hydrogen 3.009 N/A ARG 235.A N GLU 230.A O no hydrogen 3.178 N/A ASN 238.A N GLY 234.A O no hydrogen 3.212 N/A ILE 243.A N LYS 239.A O no hydrogen 2.983 N/A SER 244.A N ILE 240.A O no hydrogen 2.847 N/A SER 244.A OG THR 26.A O no hydrogen 3.222 N/A LEU 245.A N ASP 242.A O no hydrogen 3.346 N/A ILE 246.A N ILE 243.A O no hydrogen 3.074 N/A GLY 247.A N LYS 205.A O no hydrogen 2.864 N/A ARG 248.A NE ASP 289.A OD2 no hydrogen 3.015 N/A ARG 248.A NH1 GLU 326.A O no hydrogen 2.771 N/A ARG 248.A NH2 ASP 289.A OD1 no hydrogen 2.449 N/A ARG 248.A NH2 ASP 289.A OD2 no hydrogen 3.395 N/A ARG 248.A NH2 GLU 326.A O no hydrogen 2.814 N/A LEU 249.A N SER 287.A O no hydrogen 2.788 N/A LEU 250.A N ALA 207.A O no hydrogen 2.947 N/A ILE 251.A N ASP 289.A O no hydrogen 2.826 N/A CYS 252.A N VAL 209.A O no hydrogen 3.166 N/A ASP 257.A N LEU 214.A O no hydrogen 3.369 N/A SER 262.A OG SER 262.A O no hydrogen 2.587 N/A ASN 264.A N GLU 267.A OE2 no hydrogen 2.963 N/A MET 269.A N LYS 265.A O no hydrogen 2.882 N/A ILE 270.A N ASP 266.A O no hydrogen 2.891 N/A SER 271.A N GLU 267.A O no hydrogen 2.947 N/A SER 271.A OG GLU 267.A O no hydrogen 2.988 N/A LEU 272.A N LEU 268.A O no hydrogen 2.881 N/A THR 273.A N MET 269.A O no hydrogen 2.854 N/A THR 273.A OG1 MET 269.A O no hydrogen 2.842 N/A THR 273.A OG1 ILE 270.A O no hydrogen 2.499 N/A GLU 274.A N ILE 270.A O no hydrogen 2.947 N/A PHE 275.A N SER 271.A O no hydrogen 2.939 N/A SER 276.A N LEU 272.A O no hydrogen 2.857 N/A LYS 277.A N THR 273.A O no hydrogen 2.851 N/A PHE 278.A N GLU 274.A O no hydrogen 2.978 N/A LEU 279.A N PHE 275.A O no hydrogen 2.899 N/A HIS 280.A N SER 276.A O no hydrogen 2.865 N/A ASN 281.A N LYS 277.A O no hydrogen 2.919 N/A ILE 282.A N LEU 279.A O no hydrogen 3.089 N/A LEU 283.A N LEU 279.A O no hydrogen 2.580 N/A ILE 286.A N ILE 282.A O no hydrogen 3.025 N/A VAL 288.A N ILE 327.A O no hydrogen 2.911 N/A ASP 289.A N LEU 249.A O no hydrogen 2.832 N/A ILE 290.A N ASN 329.A O no hydrogen 3.117 N/A ASN 295.A ND2 ASN 213.A OD1 no hydrogen 3.147 N/A SER 298.A N ASP 296.A O no hydrogen 2.619 N/A LEU 302.A N THR 389.A O no hydrogen 3.022 N/A GLN 304.A N LEU 302.A O no hydrogen 2.686 N/A GLN 304.A NE2 GLY 293.A O no hydrogen 3.385 N/A GLN 304.A NE2 ASP 299.A O no hydrogen 2.525 N/A GLN 305.A NE2 LEU 44.A O no hydrogen 2.584 N/A SER 315.A OG HIS 280.A ND1 no hydrogen 3.351 N/A LEU 316.A N ASP 313.A O no hydrogen 3.155 N/A GLU 317.A N LYS 314.A O no hydrogen 3.396 N/A PHE 320.A N LEU 316.A O no hydrogen 2.902 N/A PHE 320.A N GLU 317.A O no hydrogen 3.252 N/A VAL 331.A N ILE 290.A O no hydrogen 3.387 N/A ASN 333.A N GLN 304.A O no hydrogen 2.831 N/A ASN 333.A ND2 LEU 302.A O no hydrogen 2.895 N/A PHE 337.A N VAL 344.A O no hydrogen 2.879 N/A SER 338.A N ASP 32.A OD1 no hydrogen 3.211 N/A SER 338.A OG ASP 33.A OD2 no hydrogen 2.710 N/A TYR 339.A OH ASP 289.A OD2 no hydrogen 2.371 N/A ASN 340.A N VAL 31.A O no hydrogen 3.203 N/A VAL 342.A N TYR 339.A O no hydrogen 2.873 N/A VAL 344.A N PHE 337.A O no hydrogen 2.896 N/A LEU 345.A N VAL 405.A O no hydrogen 2.838 N/A ALA 346.A N TYR 335.A O no hydrogen 3.374 N/A VAL 347.A N ILE 407.A O no hydrogen 2.993 N/A SER 348.A N ASN 333.A OD1 no hydrogen 2.734 N/A LYS 350.A NZ ASP 388.A O no hydrogen 3.255 N/A ASN 351.A ND2 ILE 382.A O no hydrogen 2.925 N/A ILE 352.A N ASN 351.A OD1 no hydrogen 2.721 N/A ASN 353.A N GLY 349.A O no hydrogen 3.229 N/A ASP 354.A N LYS 350.A O no hydrogen 2.879 N/A ILE 355.A N ASN 351.A O no hydrogen 2.958 N/A CYS 356.A N ILE 352.A O no hydrogen 2.853 N/A LYS 357.A N ASN 353.A O no hydrogen 3.016 N/A TYR 358.A N ILE 355.A O no hydrogen 3.177 N/A TYR 358.A OH TYR 116.A OH no hydrogen 3.229 N/A VAL 359.A N LYS 115.A O no hydrogen 2.532 N/A ARG 369.A N ASP 365.A O no hydrogen 2.860 N/A LEU 370.A N ILE 366.A O no hydrogen 2.909 N/A ASP 371.A N GLU 367.A O no hydrogen 2.901 N/A LEU 372.A N HIS 368.A O no hydrogen 2.895 N/A MET 373.A N ARG 369.A O no hydrogen 2.904 N/A GLU 374.A N LEU 370.A O no hydrogen 2.893 N/A CYS 375.A N ASP 371.A O no hydrogen 2.903 N/A CYS 375.A SG PRO 166.A O no hydrogen 3.270 N/A THR 376.A N LEU 372.A O no hydrogen 2.892 N/A THR 376.A OG1 LEU 372.A O no hydrogen 3.107 N/A MET 377.A N MET 373.A O no hydrogen 2.917 N/A LYS 378.A N GLU 374.A O no hydrogen 2.891 N/A TRP 379.A N CYS 375.A O no hydrogen 2.914 N/A GLN 380.A N MET 377.A O no hydrogen 3.251 N/A THR 389.A N THR 385.A O no hydrogen 3.087 N/A LEU 390.A N ALA 386.A O no hydrogen 3.071 N/A VAL 398.A N ASP 395.A O no hydrogen 3.196 N/A HIS 404.A N ASP 343.A O no hydrogen 2.865 N/A TYR 406.A N LYS 427.A O no hydrogen 2.502 N/A ILE 407.A N LEU 345.A O no hydrogen 2.645 N/A VAL 408.A N ILE 429.A O no hydrogen 3.192 N/A ALA 409.A N VAL 347.A O no hydrogen 3.303 N/A ASN 410.A ND2 SER 348.A O no hydrogen 3.028 N/A GLN 411.A NE2 ALA 409.A O no hydrogen 3.162 N/A ARG 417.A N ILE 428.A O no hydrogen 3.235 N/A ARG 417.A NH2 ASP 371.A OD1 no hydrogen 3.279 N/A VAL 419.A N ILE 426.A O no hydrogen 3.083 N/A ILE 421.A N LYS 424.A O no hydrogen 3.015 N/A LYS 424.A N ILE 421.A O no hydrogen 3.122 N/A ASN 425.A ND2 VAL 419.A O no hydrogen 2.764 N/A ILE 426.A N VAL 419.A O no hydrogen 3.241 N/A LYS 427.A N HIS 404.A O no hydrogen 2.961 N/A ILE 428.A N ARG 417.A O no hydrogen 3.050 N/A ILE 429.A N TYR 406.A O no hydrogen 2.691 N/A SER 430.A N GLY 415.A O no hydrogen 3.219 N/A SER 430.A OG TYR 413.A O no hydrogen 3.018 N/A PHE 434.A N GLY 211.A O no hydrogen 3.030 N/A SER 435.A N GLY 211.A O no hydrogen 2.716 N/A THR 437.A OG1 SER 436.A O no hydrogen 2.773 N/A THR 437.A OG1 THR 437.A O no hydrogen 2.351 N/A MET 439.A N THR 437.A O no hydrogen 2.692 N/A ILE 440.A N VAL 453.A O no hydrogen 2.903 N/A ILE 441.A N LEU 208.A O no hydrogen 3.261 N/A LEU 442.A N GLU 451.A O no hydrogen 2.651 N/A LEU 443.A N ILE 206.A O no hydrogen 2.884 N/A ASP 444.A N GLU 449.A O no hydrogen 2.747 N/A LEU 445.A N GLY 204.A O no hydrogen 2.935 N/A GLU 449.A N ASP 444.A O no hydrogen 3.362 N/A GLU 451.A N LEU 442.A O no hydrogen 2.938 N/A VAL 453.A N ILE 440.A O no hydrogen 2.885 N/A ILE 455.A N GLY 438.A O no hydrogen 3.447 N/A