Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8tlt_F.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LEU 6.A N HIS 2.A O no hydrogen 3.351 N/A LEU 7.A N MET 3.A O no hydrogen 2.893 N/A THR 8.A N ASP 4.A O no hydrogen 2.909 N/A LYS 9.A N ALA 5.A O no hydrogen 2.872 N/A LYS 9.A N LEU 6.A O no hydrogen 3.196 N/A PHE 10.A N LEU 6.A O no hydrogen 2.938 N/A ASN 11.A N LEU 7.A O no hydrogen 2.890 N/A ARG 27.A NE SER 284.A O no hydrogen 3.041 N/A ARG 27.A NH1 LEU 231.A O no hydrogen 2.860 N/A ARG 27.A NH1 ILE 242.A O no hydrogen 3.384 N/A ARG 27.A NH2 LEU 231.A O no hydrogen 3.152 N/A ARG 27.A NH2 SER 284.A O no hydrogen 2.956 N/A VAL 28.A N SER 243.A O no hydrogen 3.336 N/A VAL 31.A N ASN 339.A OD1 no hydrogen 3.521 N/A ASP 33.A N SER 337.A O no hydrogen 3.046 N/A ASN 34.A N ASP 32.A OD1 no hydrogen 3.291 N/A ASN 34.A ND2 GLU 335.A O no hydrogen 2.947 N/A LEU 35.A N ASP 32.A O no hydrogen 3.233 N/A SER 39.A OG ASN 37.A OD1 no hydrogen 3.156 N/A SER 39.A OG LYS 38.A O no hydrogen 2.599 N/A GLN 43.A N ASN 40.A O no hydrogen 3.323 N/A ARG 49.A N CYS 45.A O no hydrogen 3.518 N/A TYR 59.A N TYR 55.A O no hydrogen 2.943 N/A GLN 60.A N TYR 56.A O no hydrogen 2.876 N/A TYR 61.A N HIS 57.A O no hydrogen 2.925 N/A ARG 62.A N ILE 58.A O no hydrogen 2.906 N/A LEU 63.A N TYR 59.A O no hydrogen 2.928 N/A LYS 64.A N GLN 60.A O no hydrogen 2.908 N/A THR 65.A N TYR 61.A O no hydrogen 2.955 N/A THR 65.A OG1 TYR 61.A O no hydrogen 2.592 N/A THR 65.A OG1 ARG 62.A O no hydrogen 2.978 N/A PHE 66.A N ARG 62.A O no hydrogen 2.948 N/A ARG 67.A N LEU 63.A O no hydrogen 2.901 N/A GLU 68.A N LYS 64.A O no hydrogen 2.940 N/A ARG 69.A N THR 65.A O no hydrogen 2.951 N/A ARG 69.A NH1 GLN 379.A OE1 no hydrogen 2.883 N/A ARG 69.A NH1 LEU 399.A O no hydrogen 2.871 N/A ARG 69.A NH2 LEU 399.A O no hydrogen 3.272 N/A VAL 70.A N PHE 66.A O no hydrogen 2.908 N/A LEU 71.A N ARG 67.A O no hydrogen 2.881 N/A LYS 72.A N GLU 68.A O no hydrogen 2.936 N/A GLU 73.A N ARG 69.A O no hydrogen 2.976 N/A CYS 74.A N VAL 70.A O no hydrogen 2.851 N/A ASP 75.A N LEU 71.A O no hydrogen 2.898 N/A LYS 76.A N LYS 72.A O no hydrogen 2.945 N/A ARG 77.A N GLU 73.A O no hydrogen 2.889 N/A ARG 77.A NH1 ILE 188.A O no hydrogen 3.123 N/A TRP 78.A N CYS 74.A O no hydrogen 2.621 N/A PHE 82.A N ASP 79.A O no hydrogen 3.210 N/A LEU 84.A N GLN 87.A O no hydrogen 2.848 N/A VAL 89.A N PHE 82.A O no hydrogen 3.282 N/A LEU 90.A N PRO 103.A O no hydrogen 3.172 N/A LYS 92.A N TRP 105.A O no hydrogen 3.184 N/A ASP 97.A N LYS 94.A O no hydrogen 3.458 N/A CYS 104.A N GLY 175.A O no hydrogen 3.438 N/A CYS 104.A SG GLN 102.A O no hydrogen 3.993 N/A CYS 104.A SG GLY 175.A O no hydrogen 3.967 N/A TRP 105.A N LEU 90.A O no hydrogen 3.422 N/A CYS 106.A N ILE 173.A O no hydrogen 3.052 N/A CYS 106.A SG LYS 92.A O no hydrogen 3.807 N/A CYS 106.A SG ASP 93.A O no hydrogen 3.581 N/A CYS 106.A SG VAL 107.A O no hydrogen 3.522 N/A GLY 108.A N VAL 171.A O no hydrogen 3.108 N/A SER 109.A N GLU 147.A O no hydrogen 2.682 N/A TYR 111.A N MET 145.A O no hydrogen 2.689 N/A LYS 115.A N VAL 358.A O no hydrogen 2.853 N/A LYS 115.A NZ TYR 138.A O no hydrogen 3.229 N/A TYR 116.A N TYR 138.A OH no hydrogen 3.059 N/A LYS 117.A N LYS 356.A O no hydrogen 3.334 N/A LYS 117.A NZ CYS 355.A O no hydrogen 2.875 N/A LEU 121.A N LYS 117.A O no hydrogen 3.181 N/A ASP 122.A N PRO 118.A O no hydrogen 2.916 N/A GLU 123.A N ASN 119.A O no hydrogen 2.884 N/A VAL 124.A N VAL 120.A O no hydrogen 2.941 N/A ILE 125.A N LEU 121.A O no hydrogen 2.897 N/A ASN 126.A N ASP 122.A O no hydrogen 3.438 N/A SER 137.A N ASP 133.A O no hydrogen 3.117 N/A TYR 138.A N LEU 134.A O no hydrogen 2.926 N/A THR 139.A N THR 135.A O no hydrogen 2.900 N/A MET 145.A N TYR 111.A O no hydrogen 3.217 N/A LEU 146.A N VAL 153.A O no hydrogen 3.011 N/A GLU 147.A N SER 109.A O no hydrogen 2.929 N/A ASP 148.A N GLY 151.A O no hydrogen 3.395 N/A VAL 153.A N LEU 146.A O no hydrogen 3.104 N/A LEU 155.A N ILE 144.A O no hydrogen 3.005 N/A VAL 156.A N PHE 183.A O no hydrogen 2.890 N/A GLY 168.A N ILE 110.A O no hydrogen 2.805 N/A VAL 169.A N ILE 166.A O no hydrogen 3.348 N/A VAL 171.A N GLY 108.A O no hydrogen 3.022 N/A GLY 172.A N CYS 189.A O no hydrogen 3.226 N/A ILE 173.A N CYS 106.A O no hydrogen 2.917 N/A LEU 174.A N ASP 187.A O no hydrogen 3.127 N/A GLY 175.A N CYS 104.A O no hydrogen 3.127 N/A ALA 178.A N THR 182.A O no hydrogen 2.831 N/A THR 182.A N ALA 180.A O no hydrogen 2.753 N/A PHE 183.A N LEU 154.A O no hydrogen 2.433 N/A GLN 184.A N MET 176.A O no hydrogen 2.657 N/A VAL 185.A N VAL 156.A O no hydrogen 3.118 N/A LEU 186.A N LEU 174.A O no hydrogen 2.887 N/A ASP 187.A N LEU 174.A O no hydrogen 3.254 N/A CYS 189.A SG TYR 190.A O no hydrogen 3.956 N/A GLN 196.A NE2 TRP 402.A O no hydrogen 3.516 N/A GLN 196.A NE2 PRO 403.A O no hydrogen 2.829 N/A GLN 196.A NE2 ASN 425.A O no hydrogen 3.337 N/A ASN 197.A ND2 ASP 342.A OD1 no hydrogen 3.166 N/A ASN 197.A ND2 ASP 342.A OD2 no hydrogen 3.555 N/A LYS 204.A N LEU 244.A O no hydrogen 2.931 N/A LYS 204.A NZ GLU 451.A OE2 no hydrogen 3.569 N/A ILE 205.A N LEU 443.A O no hydrogen 2.807 N/A ALA 206.A N ARG 247.A O no hydrogen 3.036 N/A LEU 207.A N ILE 441.A O no hydrogen 2.789 N/A VAL 208.A N LEU 249.A O no hydrogen 3.034 N/A SER 209.A OG PRO 432.A O no hydrogen 3.173 N/A GLY 210.A N GLY 252.A O no hydrogen 2.975 N/A ASN 212.A N ASN 253.A O no hydrogen 2.800 N/A ASN 212.A ND2 SER 435.A OG no hydrogen 3.045 N/A LEU 213.A N SER 254.A O no hydrogen 2.995 N/A ASN 215.A ND2 GLU 266.A O no hydrogen 3.485 N/A SER 217.A N ASN 214.A OD1 no hydrogen 3.272 N/A ARG 220.A NH1 ASN 212.A O no hydrogen 2.627 N/A LEU 222.A N PRO 218.A O no hydrogen 3.459 N/A ARG 223.A N ASP 219.A O no hydrogen 2.920 N/A LEU 224.A N ARG 220.A O no hydrogen 2.903 N/A GLU 225.A N LEU 221.A O no hydrogen 2.904 N/A ILE 226.A N LEU 222.A O no hydrogen 2.926 N/A LEU 227.A N ARG 223.A O no hydrogen 2.895 N/A ARG 228.A N LEU 224.A O no hydrogen 2.901 N/A GLU 229.A N GLU 225.A O no hydrogen 2.920 N/A PHE 230.A N ILE 226.A O no hydrogen 2.886 N/A LEU 231.A N LEU 227.A O no hydrogen 2.917 N/A MET 232.A N ARG 228.A O no hydrogen 3.182 N/A MET 232.A N GLU 229.A O no hydrogen 3.308 N/A MET 232.A SD ASN 280.A O no hydrogen 3.936 N/A GLY 233.A N PHE 230.A O no hydrogen 3.165 N/A ARG 234.A N GLU 229.A O no hydrogen 3.072 N/A ASP 241.A N LYS 238.A O no hydrogen 3.168 N/A ILE 242.A N LYS 238.A O no hydrogen 3.107 N/A SER 243.A N ILE 239.A O no hydrogen 3.348 N/A SER 243.A OG THR 26.A O no hydrogen 3.463 N/A LEU 244.A N ASP 241.A O no hydrogen 3.184 N/A ILE 245.A N ILE 242.A O no hydrogen 3.171 N/A GLY 246.A N LYS 204.A O no hydrogen 2.917 N/A ARG 247.A NH1 ASP 288.A OD1 no hydrogen 2.821 N/A ARG 247.A NH1 GLU 325.A O no hydrogen 3.376 N/A ARG 247.A NH2 ILE 30.A O no hydrogen 3.159 N/A ARG 247.A NH2 GLU 325.A O no hydrogen 3.070 N/A LEU 248.A N SER 286.A O no hydrogen 2.808 N/A LEU 249.A N ALA 206.A O no hydrogen 2.762 N/A ILE 250.A N ASP 288.A O no hydrogen 2.764 N/A CYS 251.A N VAL 208.A O no hydrogen 2.828 N/A SER 254.A N ASP 295.A OD2 no hydrogen 3.374 N/A VAL 255.A N ASP 295.A OD1 no hydrogen 3.128 N/A ASP 256.A N LEU 213.A O no hydrogen 3.247 N/A SER 261.A OG SER 261.A O no hydrogen 2.563 N/A MET 268.A N LYS 264.A O no hydrogen 2.885 N/A ILE 269.A N ASP 265.A O no hydrogen 2.914 N/A SER 270.A N GLU 266.A O no hydrogen 2.995 N/A SER 270.A OG GLU 266.A O no hydrogen 3.191 N/A LEU 271.A N LEU 267.A O no hydrogen 2.874 N/A THR 272.A N MET 268.A O no hydrogen 2.846 N/A THR 272.A OG1 MET 268.A O no hydrogen 2.912 N/A THR 272.A OG1 ILE 269.A O no hydrogen 2.518 N/A GLU 273.A N ILE 269.A O no hydrogen 2.988 N/A PHE 274.A N SER 270.A O no hydrogen 2.960 N/A SER 275.A N LEU 271.A O no hydrogen 2.844 N/A LYS 276.A N THR 272.A O no hydrogen 2.862 N/A PHE 277.A N GLU 273.A O no hydrogen 3.017 N/A LEU 278.A N PHE 274.A O no hydrogen 2.924 N/A HIS 279.A N SER 275.A O no hydrogen 2.853 N/A ASN 280.A N LYS 276.A O no hydrogen 2.948 N/A ILE 281.A N PHE 277.A O no hydrogen 2.949 N/A ILE 281.A N LEU 278.A O no hydrogen 3.227 N/A LEU 282.A N LEU 278.A O no hydrogen 2.742 N/A SER 284.A N ILE 281.A O no hydrogen 3.173 N/A ILE 285.A N ILE 281.A O no hydrogen 3.218 N/A SER 286.A OG GLU 325.A O no hydrogen 3.354 N/A VAL 287.A N ILE 326.A O no hydrogen 2.966 N/A ASP 288.A N LEU 248.A O no hydrogen 2.935 N/A ILE 289.A N ASN 328.A O no hydrogen 2.968 N/A ASN 294.A ND2 ASN 212.A OD1 no hydrogen 3.635 N/A ASN 294.A ND2 ASN 253.A OD1 no hydrogen 2.898 N/A SER 297.A N ASP 295.A O no hydrogen 2.616 N/A LEU 301.A N THR 388.A O no hydrogen 3.018 N/A GLN 303.A N LEU 301.A O no hydrogen 2.593 N/A GLN 303.A NE2 GLY 292.A O no hydrogen 3.288 N/A GLN 304.A N ASP 298.A OD1 no hydrogen 3.278 N/A GLN 304.A NE2 PHE 42.A O no hydrogen 3.335 N/A SER 314.A OG HIS 279.A ND1 no hydrogen 3.265 N/A LEU 315.A N ASP 312.A O no hydrogen 3.173 N/A GLU 316.A N LYS 313.A O no hydrogen 3.372 N/A PHE 319.A N LEU 315.A O no hydrogen 2.934 N/A ASN 320.A N SER 317.A O no hydrogen 3.323 N/A ASN 328.A N VAL 287.A O no hydrogen 3.317 N/A VAL 330.A N ILE 289.A O no hydrogen 3.210 N/A THR 331.A OG1 PRO 333.A O no hydrogen 2.787 N/A ASN 332.A N GLN 303.A O no hydrogen 3.173 N/A ASN 332.A ND2 LEU 301.A O no hydrogen 3.451 N/A TYR 334.A N ALA 345.A O no hydrogen 3.152 N/A PHE 336.A N VAL 343.A O no hydrogen 2.606 N/A SER 337.A N ASP 32.A OD1 no hydrogen 3.136 N/A SER 337.A OG ASP 33.A OD2 no hydrogen 3.259 N/A TYR 338.A N VAL 341.A O no hydrogen 2.953 N/A TYR 338.A OH ASP 288.A OD2 no hydrogen 2.758 N/A ASN 339.A N VAL 31.A O no hydrogen 3.079 N/A ASN 339.A ND2 ARG 29.A O no hydrogen 3.506 N/A VAL 341.A N TYR 338.A O no hydrogen 3.050 N/A ASP 342.A N HIS 404.A ND1 no hydrogen 3.233 N/A VAL 343.A N PHE 336.A O no hydrogen 2.557 N/A LEU 344.A N VAL 405.A O no hydrogen 2.804 N/A ALA 345.A N TYR 334.A O no hydrogen 3.093 N/A VAL 346.A N ILE 407.A O no hydrogen 2.959 N/A SER 347.A N ASN 332.A OD1 no hydrogen 2.971 N/A LYS 349.A NZ ASP 353.A OD1 no hydrogen 2.883 N/A LYS 349.A NZ ASP 353.A OD2 no hydrogen 3.563 N/A LYS 349.A NZ ASP 387.A O no hydrogen 3.338 N/A ASN 350.A ND2 ILE 381.A O no hydrogen 2.890 N/A ASN 352.A N GLY 348.A O no hydrogen 2.968 N/A ASN 352.A ND2 ASN 410.A O no hydrogen 3.397 N/A ASP 353.A N ASN 350.A O no hydrogen 3.068 N/A ILE 354.A N ASN 350.A O no hydrogen 2.943 N/A CYS 355.A N ILE 351.A O no hydrogen 3.158 N/A CYS 355.A SG ILE 351.A O no hydrogen 3.238 N/A LYS 356.A N ASP 353.A O no hydrogen 3.433 N/A TYR 357.A N ILE 354.A O no hydrogen 3.371 N/A VAL 358.A N LYS 115.A O no hydrogen 2.415 N/A ILE 365.A N ASP 364.A OD1 no hydrogen 2.718 N/A ARG 368.A N ASP 364.A O no hydrogen 2.943 N/A ARG 368.A NH1 ASN 352.A OD1 no hydrogen 3.036 N/A LEU 369.A N ILE 365.A O no hydrogen 2.928 N/A ASP 370.A N GLU 366.A O no hydrogen 2.881 N/A LEU 371.A N HIS 367.A O no hydrogen 2.902 N/A MET 372.A N ARG 368.A O no hydrogen 2.928 N/A GLU 373.A N LEU 369.A O no hydrogen 2.903 N/A CYS 374.A N ASP 370.A O no hydrogen 2.880 N/A CYS 374.A SG PRO 164.A O no hydrogen 3.803 N/A THR 375.A N LEU 371.A O no hydrogen 2.898 N/A MET 376.A N MET 372.A O no hydrogen 2.955 N/A LYS 377.A N GLU 373.A O no hydrogen 2.890 N/A TRP 378.A N CYS 374.A O no hydrogen 2.868 N/A GLN 379.A N MET 376.A O no hydrogen 3.255 N/A GLN 379.A NE2 THR 192.A O no hydrogen 2.974 N/A ILE 381.A N PHE 397.A O no hydrogen 2.968 N/A THR 384.A OG1 THR 388.A OG1 no hydrogen 2.933 N/A ASP 387.A N THR 384.A O no hydrogen 3.246 N/A THR 388.A N THR 384.A O no hydrogen 2.887 N/A THR 388.A N ALA 385.A O no hydrogen 3.309 N/A THR 388.A OG1 ASP 353.A OD1 no hydrogen 3.364 N/A THR 388.A OG1 THR 384.A O no hydrogen 2.475 N/A LEU 389.A N ALA 385.A O no hydrogen 3.115 N/A VAL 398.A N ASP 395.A O no hydrogen 3.272 N/A LEU 399.A N GLN 379.A O no hydrogen 2.777 N/A LYS 401.A NZ GLU 335.A OE2 no hydrogen 3.295 N/A TRP 402.A N PRO 195.A O no hydrogen 3.073 N/A HIS 404.A N ASP 342.A O no hydrogen 3.009 N/A HIS 404.A NE2 ASN 197.A O no hydrogen 2.718 N/A VAL 405.A N ASP 342.A O no hydrogen 3.134 N/A TYR 406.A N LYS 427.A O no hydrogen 2.677 N/A ILE 407.A N LEU 344.A O no hydrogen 2.676 N/A VAL 408.A N ILE 429.A O no hydrogen 3.088 N/A ALA 409.A N VAL 346.A O no hydrogen 3.053 N/A ASN 410.A N SER 209.A OG no hydrogen 3.233 N/A ASN 410.A ND2 SER 347.A O no hydrogen 3.410 N/A GLN 411.A N VAL 431.A O no hydrogen 3.260 N/A GLN 411.A NE2 ASN 352.A OD1 no hydrogen 2.730 N/A GLN 411.A NE2 ASN 410.A O no hydrogen 3.011 N/A ARG 417.A N ILE 428.A O no hydrogen 3.038 N/A ARG 417.A NH1 ASP 370.A OD1 no hydrogen 3.027 N/A ARG 417.A NH1 GLU 373.A OE2 no hydrogen 3.048 N/A VAL 419.A N ILE 426.A O no hydrogen 2.877 N/A ILE 421.A N LYS 424.A O no hydrogen 3.086 N/A LYS 424.A N ILE 421.A O no hydrogen 3.259 N/A ASN 425.A ND2 VAL 419.A O no hydrogen 3.282 N/A ILE 426.A N VAL 419.A O no hydrogen 2.937 N/A LYS 427.A N HIS 404.A O no hydrogen 3.047 N/A ILE 428.A N ARG 417.A O no hydrogen 2.955 N/A ILE 429.A N TYR 406.A O no hydrogen 2.782 N/A SER 430.A N GLY 415.A O no hydrogen 2.779 N/A SER 430.A OG TYR 413.A O no hydrogen 2.704 N/A VAL 431.A N VAL 408.A O no hydrogen 2.928 N/A PHE 434.A N GLY 210.A O no hydrogen 3.199 N/A SER 435.A N GLY 210.A O no hydrogen 2.878 N/A THR 437.A OG1 GLU 433.A O no hydrogen 3.554 N/A THR 437.A OG1 SER 436.A O no hydrogen 2.450 N/A THR 437.A OG1 THR 437.A O no hydrogen 2.512 N/A MET 439.A N THR 437.A O no hydrogen 2.503 N/A ILE 440.A N VAL 453.A O no hydrogen 2.684 N/A ILE 441.A N LEU 207.A O no hydrogen 3.156 N/A LEU 442.A N GLU 451.A O no hydrogen 2.658 N/A LEU 443.A N ILE 205.A O no hydrogen 2.804 N/A ASP 444.A N GLU 449.A O no hydrogen 2.932 N/A LEU 445.A N GLY 203.A O no hydrogen 2.953 N/A GLU 446.A N ASP 444.A OD1 no hydrogen 3.388 N/A GLU 451.A N LEU 442.A O no hydrogen 2.812 N/A VAL 453.A N ILE 440.A O no hydrogen 2.852 N/A LYS 454.A NZ ASP 456.A OD1 no hydrogen 3.436 N/A ILE 455.A N GLY 438.A O no hydrogen 3.307 N/A