Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8twq_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LYS 1.A N ARG 101.A O no hydrogen 3.025 N/A GLY 3.A N PHE 99.A O no hydrogen 2.843 N/A TYR 5.A N ILE 97.A O no hydrogen 2.908 N/A ALA 6.A N GLU 130.A O no hydrogen 2.756 N/A THR 7.A N ASP 95.A O no hydrogen 2.733 N/A THR 7.A OG1 ASP 95.A O no hydrogen 3.376 N/A TYR 8.A N GLN 128.A O no hydrogen 3.163 N/A TYR 8.A OH GLU 130.A OE1 no hydrogen 2.882 N/A ARG 9.A N ARG 18.A O no hydrogen 2.661 N/A ARG 9.A NH1 SER 120.A O no hydrogen 2.786 N/A ARG 9.A NH2 SER 19.A O no hydrogen 2.605 N/A SER 10.A N ARG 126.A O no hydrogen 2.680 N/A LYS 11.A N ASP 16.A O no hydrogen 2.828 N/A LYS 11.A NZ SER 122.A OG no hydrogen 3.341 N/A LYS 15.A N ASN 12.A O no hydrogen 2.657 N/A ASP 16.A N LYS 11.A O no hydrogen 2.906 N/A LYS 17.A NZ VAL 263.A O no hydrogen 2.554 N/A LYS 17.A NZ LYS 265.A O no hydrogen 3.501 N/A ARG 18.A N ARG 9.A O no hydrogen 2.725 N/A ARG 18.A NE GLU 125.A OE1 no hydrogen 3.369 N/A ARG 18.A NH2 GLU 125.A OE2 no hydrogen 2.553 N/A SER 19.A N LYS 267.A O no hydrogen 2.638 N/A SER 19.A OG ASN 21.A OD1 no hydrogen 2.791 N/A SER 19.A OG ASP 95.A OD1 no hydrogen 3.271 N/A ASN 21.A N SER 19.A OG no hydrogen 3.045 N/A PHE 25.A N ASN 21.A O no hydrogen 2.985 N/A LEU 26.A N LEU 22.A O no hydrogen 2.864 N/A ASN 27.A N SER 23.A O no hydrogen 2.913 N/A SER 28.A N VAL 24.A O no hydrogen 3.062 N/A SER 28.A N PHE 25.A O no hydrogen 3.236 N/A SER 28.A OG PHE 25.A O no hydrogen 2.505 N/A LEU 29.A N LEU 26.A O no hydrogen 3.013 N/A HIS 31.A ND1 ILE 42.A O no hydrogen 3.218 N/A LEU 33.A N LEU 40.A O no hydrogen 2.974 N/A GLN 34.A NE2 GLY 36.A O no hydrogen 2.526 N/A VAL 35.A N ASN 38.A O no hydrogen 2.773 N/A ASN 38.A N VAL 35.A O no hydrogen 2.977 N/A TYR 39.A N THR 55.A O no hydrogen 2.695 N/A LEU 40.A N LEU 33.A O no hydrogen 2.711 N/A TYR 41.A N THR 53.A O no hydrogen 2.956 N/A TYR 41.A OH HIS 32.A ND1 no hydrogen 3.388 N/A TYR 41.A OH ASN 65.A OD1 no hydrogen 3.095 N/A ILE 42.A N HIS 31.A O no hydrogen 3.262 N/A HIS 43.A N LEU 51.A O no hydrogen 3.013 N/A LYS 44.A NZ ASN 27.A OD1 no hydrogen 2.839 N/A ILE 45.A N THR 49.A O no hydrogen 2.946 N/A ASP 46.A N THR 49.A O no hydrogen 3.426 N/A THR 49.A N ASP 46.A O no hydrogen 3.056 N/A PHE 50.A N LEU 90.A O no hydrogen 2.762 N/A LEU 51.A N HIS 43.A O no hydrogen 2.628 N/A PHE 52.A N SER 88.A O no hydrogen 3.031 N/A THR 53.A N TYR 41.A O no hydrogen 2.871 N/A THR 53.A OG1 LEU 84.A O no hydrogen 2.667 N/A LYS 54.A N PHE 86.A O no hydrogen 3.198 N/A LYS 54.A NZ ASP 110.A OD2 no hydrogen 3.106 N/A THR 55.A N TYR 39.A O no hydrogen 3.068 N/A ASP 57.A N THR 55.A OG1 no hydrogen 2.987 N/A LYS 58.A NZ TYR 39.A OH no hydrogen 3.061 N/A SER 59.A N ASP 57.A OD1 no hydrogen 3.069 N/A SER 59.A OG ASP 57.A OD1 no hydrogen 3.340 N/A LEU 60.A N ASP 57.A OD1 no hydrogen 3.454 N/A VAL 61.A N ASP 57.A O no hydrogen 3.234 N/A GLN 62.A N LYS 58.A O no hydrogen 3.070 N/A LYS 63.A N SER 59.A O no hydrogen 3.184 N/A ILE 64.A N LEU 60.A O no hydrogen 3.019 N/A ASN 65.A N VAL 61.A O no hydrogen 3.038 N/A ARG 66.A N GLN 62.A O no hydrogen 3.067 N/A SER 67.A N LYS 63.A O no hydrogen 2.774 N/A LYS 68.A N ILE 64.A O no hydrogen 2.971 N/A SER 70.A N ASP 73.A OD2 no hydrogen 3.382 N/A SER 70.A OG GLU 72.A OE1 no hydrogen 2.713 N/A ASP 73.A N SER 70.A OG no hydrogen 2.950 N/A ILE 74.A N SER 70.A O no hydrogen 3.139 N/A LYS 75.A N VAL 71.A O no hydrogen 3.140 N/A LYS 75.A NZ ASP 46.A OD1 no hydrogen 2.607 N/A ASN 76.A N GLU 72.A O no hydrogen 3.375 N/A SER 77.A N ILE 74.A O no hydrogen 3.206 N/A SER 77.A OG ASP 73.A O no hydrogen 3.020 N/A ALA 79.A N VAL 237.A O no hydrogen 2.721 N/A ASP 81.A N LEU 78.A O no hydrogen 3.007 N/A SER 83.A N ASP 81.A OD1 no hydrogen 3.160 N/A GLY 85.A N GLU 82.A O no hydrogen 3.444 N/A PHE 86.A N LYS 54.A O no hydrogen 2.976 N/A SER 88.A N PHE 52.A O no hydrogen 2.585 N/A SER 88.A OG PRO 106.A O no hydrogen 2.602 N/A PHE 89.A N ALA 100.A O no hydrogen 2.766 N/A LEU 90.A N PHE 50.A O no hydrogen 3.053 N/A PHE 91.A N GLY 98.A O no hydrogen 2.832 N/A VAL 92.A N LYS 48.A O no hydrogen 2.903 N/A GLU 93.A N THR 96.A O no hydrogen 3.106 N/A THR 96.A N GLU 93.A O no hydrogen 2.953 N/A THR 96.A OG1 GLU 93.A O no hydrogen 2.565 N/A THR 96.A OG1 TYR 249.A OH no hydrogen 2.474 N/A ILE 97.A N TYR 5.A O no hydrogen 2.918 N/A GLY 98.A N PHE 91.A O no hydrogen 2.965 N/A PHE 99.A N GLY 3.A O no hydrogen 2.969 N/A ALA 100.A N PHE 89.A O no hydrogen 2.933 N/A ARG 101.A N LYS 1.A O no hydrogen 2.610 N/A THR 102.A N PRO 87.A O no hydrogen 3.385 N/A THR 102.A OG1 PRO 87.A O no hydrogen 2.807 N/A GLY 105.A N THR 102.A O no hydrogen 2.748 N/A THR 107.A N ASP 110.A OD2 no hydrogen 2.901 N/A ASP 110.A N THR 107.A OG1 no hydrogen 3.407 N/A LEU 111.A N THR 107.A O no hydrogen 2.999 N/A THR 112.A N THR 108.A O no hydrogen 3.174 N/A THR 112.A OG1 THR 108.A O no hydrogen 3.042 N/A ASP 113.A N SER 109.A O no hydrogen 2.707 N/A PHE 114.A N ASP 110.A O no hydrogen 2.807 N/A LEU 115.A N LEU 111.A O no hydrogen 2.986 N/A ILE 116.A N THR 112.A O no hydrogen 3.043 N/A GLY 117.A N ASP 113.A O no hydrogen 2.862 N/A LYS 118.A N PHE 114.A O no hydrogen 2.990 N/A LYS 118.A NZ ASN 30.A OD1 no hydrogen 3.198 N/A LYS 118.A NZ HIS 32.A O no hydrogen 2.559 N/A GLY 119.A N ILE 116.A O no hydrogen 2.891 N/A SER 122.A N GLU 125.A OE2 no hydrogen 2.848 N/A GLU 125.A N SER 122.A O no hydrogen 3.172 N/A ARG 126.A N SER 10.A O no hydrogen 2.888 N/A GLN 128.A N TYR 8.A O no hydrogen 2.851 N/A GLU 130.A N ALA 6.A O no hydrogen 2.710 N/A LEU 132.A N PHE 4.A O no hydrogen 2.703 N/A GLY 134.A N ASN 2.A O no hydrogen 2.906 N/A THR 135.A N TYR 223.A O no hydrogen 2.947 N/A THR 136.A OG1 ASP 139.A OD2 no hydrogen 2.600 N/A LYS 137.A NZ GLU 226.A OE1 no hydrogen 3.318 N/A ASP 139.A N THR 136.A OG1 no hydrogen 3.300 N/A VAL 140.A N THR 136.A O no hydrogen 3.061 N/A ILE 144.A N ASP 189.A OD1 no hydrogen 3.048 N/A GLY 145.A N ARG 211.A O no hydrogen 2.588 N/A THR 147.A N ILE 182.A O no hydrogen 3.078 N/A THR 147.A OG1 GLY 145.A O no hydrogen 3.169 N/A THR 148.A N SER 209.A O no hydrogen 2.780 N/A VAL 149.A N ILE 180.A O no hydrogen 2.957 N/A LYS 150.A N ASP 207.A O no hydrogen 2.729 N/A LYS 150.A NZ ASP 254.A OD1 no hydrogen 3.202 N/A VAL 151.A N LEU 178.A O no hydrogen 2.817 N/A GLU 152.A N SER 206.A OG no hydrogen 3.211 N/A ALA 153.A N ASP 176.A O no hydrogen 3.167 N/A LEU 155.A N GLU 152.A O no hydrogen 3.186 N/A PHE 158.A N LEU 155.A O no hydrogen 3.267 N/A ASP 160.A N PRO 156.A O no hydrogen 3.276 N/A ILE 161.A N VAL 157.A O no hydrogen 2.822 N/A LEU 162.A N PHE 158.A O no hydrogen 3.107 N/A LYS 163.A N GLY 159.A O no hydrogen 3.059 N/A VAL 164.A N ASP 160.A O no hydrogen 3.031 N/A LEU 165.A N ILE 161.A O no hydrogen 3.094 N/A GLY 166.A N LYS 163.A O no hydrogen 2.803 N/A ALA 167.A N LEU 162.A O no hydrogen 2.808 N/A LEU 174.A N GLU 171.A O no hydrogen 2.731 N/A PHE 175.A N GLY 172.A O no hydrogen 3.207 N/A SER 177.A OG ASP 176.A OD2 no hydrogen 2.731 N/A LEU 178.A N VAL 151.A O no hydrogen 3.047 N/A ILE 180.A N VAL 149.A O no hydrogen 2.856 N/A ILE 182.A N THR 147.A O no hydrogen 2.629 N/A ARG 188.A N LYS 185.A O no hydrogen 2.822 N/A ILE 190.A N ILE 144.A O no hydrogen 2.990 N/A LYS 191.A N ASP 189.A OD1 no hydrogen 3.263 N/A LYS 191.A NZ HIS 142.A O no hydrogen 2.932 N/A ALA 194.A N ILE 190.A O no hydrogen 3.136 N/A LYS 195.A N LYS 191.A O no hydrogen 2.714 N/A LYS 195.A NZ VAL 140.A O no hydrogen 2.968 N/A ASP 196.A N LYS 192.A O no hydrogen 2.938 N/A ILE 197.A N VAL 193.A O no hydrogen 3.128 N/A ILE 197.A N ALA 194.A O no hydrogen 3.247 N/A ILE 198.A N ALA 194.A O no hydrogen 2.957 N/A PHE 199.A N LYS 195.A O no hydrogen 2.776 N/A ASN 200.A N ILE 197.A O no hydrogen 3.117 N/A SER 202.A N ASN 200.A OD1 no hydrogen 2.893 N/A SER 206.A N LYS 150.A O no hydrogen 2.821 N/A ASP 207.A N LYS 150.A O no hydrogen 3.482 N/A ILE 208.A N LEU 224.A O no hydrogen 2.933 N/A SER 209.A N THR 148.A O no hydrogen 3.001 N/A SER 209.A OG ASP 254.A OD2 no hydrogen 3.506 N/A LEU 210.A N HIS 222.A O no hydrogen 2.939 N/A ARG 211.A N ARG 146.A O no hydrogen 3.022 N/A ALA 212.A N THR 220.A O no hydrogen 3.006 N/A LYS 213.A N PHE 143.A O no hydrogen 3.204 N/A THR 220.A N ALA 212.A O no hydrogen 3.026 N/A HIS 222.A N LEU 210.A O no hydrogen 2.788 N/A TYR 223.A N ARG 133.A O no hydrogen 3.122 N/A LEU 224.A N ILE 208.A O no hydrogen 2.730 N/A SER 225.A OG ASP 207.A OD1 no hydrogen 3.091 N/A SER 225.A OG GLU 226.A O no hydrogen 3.097 N/A GLU 226.A N SER 206.A O no hydrogen 3.044 N/A SER 231.A N GLY 228.A O no hydrogen 3.151 N/A SER 231.A OG GLY 228.A O no hydrogen 3.512 N/A ALA 232.A N HIS 229.A O no hydrogen 3.074 N/A THR 238.A N GLU 241.A OE1 no hydrogen 3.018 N/A ASN 239.A N SER 77.A O no hydrogen 3.100 N/A ASN 239.A ND2 ILE 74.A O no hydrogen 2.930 N/A ALA 240.A N LYS 75.A O no hydrogen 3.056 N/A GLU 241.A N THR 238.A OG1 no hydrogen 3.174 N/A ILE 242.A N THR 238.A O no hydrogen 3.086 N/A ALA 243.A N ASN 239.A O no hydrogen 3.018 N/A GLU 244.A N ALA 240.A O no hydrogen 2.967 N/A GLU 245.A N GLU 241.A O no hydrogen 2.960 N/A TYR 247.A N GLU 244.A O no hydrogen 2.911 N/A CYS 248.A N GLU 245.A O no hydrogen 2.704 N/A TYR 249.A OH THR 96.A OG1 no hydrogen 2.474 N/A ALA 250.A N ALA 246.A O no hydrogen 2.850 N/A ARG 251.A N TYR 247.A O no hydrogen 3.162 N/A ARG 251.A NE ASP 207.A OD2 no hydrogen 2.877 N/A ARG 251.A NH2 ASP 207.A OD1 no hydrogen 2.920 N/A LYS 252.A NZ GLU 93.A OE1 no hydrogen 3.036 N/A LEU 256.A N LYS 252.A O no hydrogen 2.930 N/A GLU 257.A N SER 253.A O no hydrogen 3.101 N/A GLU 257.A N ASP 254.A O no hydrogen 3.361 N/A CYS 258.A N ASP 254.A O no hydrogen 3.046 N/A CYS 258.A SG LEU 132.A O no hydrogen 3.897 N/A PHE 259.A N ILE 255.A O no hydrogen 2.797 N/A LYS 260.A N LEU 256.A O no hydrogen 3.482 N/A ARG 261.A N GLU 257.A O no hydrogen 2.940 N/A GLN 262.A N CYS 258.A O no hydrogen 2.720 N/A GLN 262.A NE2 LEU 132.A O no hydrogen 3.141 N/A VAL 263.A N PHE 259.A O no hydrogen 2.765 N/A GLY 264.A N PHE 259.A O no hydrogen 3.053 N/A LYS 267.A N LYS 17.A O no hydrogen 2.923 N/A