Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8v84_b.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): SER 4.A OG LEU 3.A O no hydrogen 2.677 N/A VAL 11.A N GLU 151.A OE1 no hydrogen 2.929 N/A LEU 17.A N PRO 13.A O no hydrogen 2.870 N/A LEU 18.A N ALA 14.A O no hydrogen 2.929 N/A ASP 19.A N ASN 15.A O no hydrogen 2.918 N/A ILE 20.A N ASP 16.A O no hydrogen 2.878 N/A VAL 21.A N LEU 17.A O no hydrogen 2.939 N/A LEU 22.A N LEU 18.A O no hydrogen 2.941 N/A ASN 23.A N ASP 19.A O no hydrogen 2.905 N/A ARG 24.A N ILE 20.A O no hydrogen 2.911 N/A THR 25.A N VAL 21.A O no hydrogen 2.930 N/A THR 25.A OG1 VAL 21.A O no hydrogen 3.132 N/A THR 25.A OG1 LEU 22.A O no hydrogen 2.755 N/A GLN 26.A N LEU 22.A O no hydrogen 2.912 N/A ARG 27.A N ASN 23.A O no hydrogen 2.928 N/A ARG 27.A NE ASN 23.A OD1 no hydrogen 2.363 N/A ARG 27.A NH2 ASN 23.A OD1 no hydrogen 3.265 N/A LYS 28.A N ARG 24.A O no hydrogen 2.910 N/A THR 29.A N THR 25.A O no hydrogen 2.920 N/A THR 29.A OG1 THR 25.A O no hydrogen 2.370 N/A PHE 37.A N ARG 34.A O no hydrogen 3.156 N/A ILE 42.A N LYS 38.A O no hydrogen 2.922 N/A ARG 43.A N ILE 39.A O no hydrogen 2.890 N/A ARG 43.A NH1 GLY 119.A O no hydrogen 2.341 N/A ALA 44.A N THR 40.A O no hydrogen 2.888 N/A PHE 45.A N ARG 41.A O no hydrogen 2.892 N/A TYR 46.A N ILE 42.A O no hydrogen 2.977 N/A MET 47.A N ARG 43.A O no hydrogen 2.867 N/A ARG 48.A N ALA 44.A O no hydrogen 2.873 N/A LYS 49.A N PHE 45.A O no hydrogen 3.009 N/A VAL 50.A N TYR 46.A O no hydrogen 2.909 N/A LYS 51.A N MET 47.A O no hydrogen 2.883 N/A TYR 52.A N ARG 48.A O no hydrogen 2.912 N/A THR 53.A N LYS 49.A O no hydrogen 2.988 N/A GLY 54.A N VAL 50.A O no hydrogen 2.939 N/A GLU 55.A N LYS 51.A O no hydrogen 2.885 N/A GLY 56.A N TYR 52.A O no hydrogen 2.925 N/A PHE 57.A N THR 53.A O no hydrogen 2.972 N/A VAL 58.A N GLY 54.A O no hydrogen 2.948 N/A GLU 59.A N GLU 55.A O no hydrogen 2.876 N/A LYS 60.A N GLY 56.A O no hydrogen 2.960 N/A PHE 61.A N PHE 57.A O no hydrogen 2.983 N/A GLU 62.A N VAL 58.A O no hydrogen 2.856 N/A ASP 63.A N GLU 59.A O no hydrogen 2.946 N/A LEU 65.A N PHE 61.A O no hydrogen 2.988 N/A LYS 66.A N GLU 62.A O no hydrogen 2.883 N/A LYS 66.A NZ GLU 62.A OE2 no hydrogen 2.532 N/A GLY 67.A N ASP 63.A O no hydrogen 2.920 N/A PHE 68.A N ILE 64.A O no hydrogen 2.943 N/A ASP 73.A N ASN 70.A O no hydrogen 3.286 N/A PHE 77.A N HIS 75.A ND1 no hydrogen 2.988 N/A ARG 79.A N HIS 75.A O no hydrogen 2.883 N/A ASP 80.A N PRO 76.A O no hydrogen 2.891 N/A LEU 81.A N PHE 77.A O no hydrogen 2.934 N/A MET 82.A N HIS 78.A O no hydrogen 2.882 N/A ASP 83.A N ARG 79.A O no hydrogen 2.892 N/A THR 84.A N ASP 80.A O no hydrogen 2.886 N/A THR 84.A OG1 ASP 80.A O no hydrogen 2.835 N/A LEU 85.A N LEU 81.A O no hydrogen 2.932 N/A TYR 86.A N MET 82.A O no hydrogen 2.857 N/A TYR 86.A OH HIS 156.A ND1 no hydrogen 2.636 N/A GLU 87.A N ASP 83.A O no hydrogen 3.163 N/A LYS 88.A N ASP 83.A OD1 no hydrogen 3.016 N/A TYR 91.A N GLU 87.A O no hydrogen 2.958 N/A TYR 91.A OH PRO 69.A O no hydrogen 3.090 N/A LYS 92.A N LYS 88.A O no hydrogen 2.857 N/A ILE 93.A N ASN 89.A O no hydrogen 2.929 N/A SER 94.A N HIS 90.A O no hydrogen 2.910 N/A SER 94.A OG HIS 90.A O no hydrogen 2.980 N/A LEU 95.A N TYR 91.A O no hydrogen 2.965 N/A ALA 96.A N LYS 92.A O no hydrogen 2.863 N/A ALA 97.A N ILE 93.A O no hydrogen 2.900 N/A ILE 98.A N SER 94.A O no hydrogen 3.000 N/A SER 99.A N LEU 95.A O no hydrogen 3.379 N/A ARG 100.A N ALA 96.A O no hydrogen 2.900 N/A ALA 101.A N ALA 97.A O no hydrogen 2.909 N/A LYS 102.A N ILE 98.A O no hydrogen 2.936 N/A LYS 102.A NZ GLU 106.A OE1 no hydrogen 3.542 N/A SER 103.A N SER 99.A O no hydrogen 2.921 N/A SER 103.A OG SER 99.A O no hydrogen 3.405 N/A SER 103.A OG ARG 100.A O no hydrogen 2.517 N/A LEU 104.A N ARG 100.A O no hydrogen 2.897 N/A VAL 105.A N ALA 101.A O no hydrogen 2.913 N/A GLU 106.A N LYS 102.A O no hydrogen 2.968 N/A GLN 107.A N SER 103.A O no hydrogen 2.902 N/A VAL 108.A N LEU 104.A O no hydrogen 2.906 N/A ALA 109.A N VAL 105.A O no hydrogen 2.916 N/A ARG 110.A N GLU 106.A O no hydrogen 2.950 N/A ASP 111.A N GLN 107.A O no hydrogen 2.889 N/A TYR 112.A N VAL 108.A O no hydrogen 2.911 N/A VAL 113.A N ALA 109.A O no hydrogen 2.911 N/A ARG 114.A N ARG 110.A O no hydrogen 2.940 N/A ARG 114.A NH2 ASP 111.A OD1 no hydrogen 3.190 N/A LEU 115.A N ASP 111.A O no hydrogen 2.879 N/A LEU 116.A N TYR 112.A O no hydrogen 2.900 N/A LYS 117.A N ARG 114.A O no hydrogen 3.195 N/A GLY 119.A N LEU 116.A O no hydrogen 3.123 N/A GLN 120.A N GLN 124.A OE1 no hydrogen 2.983 N/A GLN 120.A NE2 PHE 118.A O no hydrogen 2.489 N/A CYS 125.A N SER 121.A O no hydrogen 2.903 N/A CYS 125.A SG SER 121.A O no hydrogen 3.169 N/A LYS 126.A N LEU 122.A O no hydrogen 2.893 N/A LYS 126.A NZ TYR 46.A OH no hydrogen 2.645 N/A GLN 127.A N PHE 123.A O no hydrogen 2.898 N/A LEU 128.A N GLN 124.A O no hydrogen 2.910 N/A LYS 129.A N CYS 125.A O no hydrogen 2.909 N/A ARG 130.A N LYS 126.A O no hydrogen 2.901 N/A ALA 131.A N GLN 127.A O no hydrogen 2.882 N/A ALA 132.A N LEU 128.A O no hydrogen 2.920 N/A LEU 133.A N LYS 129.A O no hydrogen 2.943 N/A GLY 134.A N ARG 130.A O no hydrogen 2.870 N/A ARG 135.A N ALA 131.A O no hydrogen 2.884 N/A MET 136.A N ALA 132.A O no hydrogen 2.973 N/A ALA 137.A N LEU 133.A O no hydrogen 2.886 N/A THR 138.A N GLY 134.A O no hydrogen 2.883 N/A ILE 139.A N ARG 135.A O no hydrogen 2.934 N/A VAL 140.A N MET 136.A O no hydrogen 2.941 N/A LYS 141.A N ALA 137.A O no hydrogen 2.895 N/A LEU 143.A N VAL 140.A O no hydrogen 2.933 N/A ARG 144.A N LYS 141.A O no hydrogen 3.218 N/A LEU 147.A N LEU 143.A O no hydrogen 3.494 N/A ALA 148.A N ARG 144.A O no hydrogen 3.379 N/A TYR 149.A N ASP 145.A O no hydrogen 2.947 N/A LEU 150.A N PRO 146.A O no hydrogen 2.933 N/A GLU 151.A N LEU 147.A O no hydrogen 2.889 N/A GLN 152.A N ALA 148.A O no hydrogen 2.996 N/A VAL 153.A N TYR 149.A O no hydrogen 2.934 N/A ARG 154.A N LEU 150.A O no hydrogen 2.836 N/A ARG 154.A NE GLU 151.A OE1 no hydrogen 3.185 N/A ARG 154.A NH2 GLU 151.A OE1 no hydrogen 3.173 N/A ARG 154.A NH2 GLU 151.A OE2 no hydrogen 2.452 N/A GLN 155.A N GLU 151.A O no hydrogen 2.974 N/A HIS 156.A N GLN 152.A O no hydrogen 2.959 N/A HIS 156.A ND1 TYR 86.A OH no hydrogen 2.636 N/A ILE 157.A N VAL 153.A O no hydrogen 2.858 N/A GLY 158.A N ARG 154.A O no hydrogen 2.943 N/A ARG 159.A N HIS 156.A O no hydrogen 3.183 N/A LEU 160.A N ILE 157.A O no hydrogen 3.204 N/A ASN 166.A N ASP 164.A OD1 no hydrogen 3.270 N/A THR 167.A OG1 ASP 164.A O no hydrogen 3.040 N/A THR 169.A OG1 THR 167.A O no hydrogen 2.753 N/A LEU 170.A N GLN 217.A O no hydrogen 2.865 N/A LEU 171.A N CYS 249.A O no hydrogen 2.912 N/A ILE 172.A N ILE 219.A O no hydrogen 2.889 N/A CYS 173.A N LEU 251.A O no hydrogen 2.943 N/A CYS 173.A SG LEU 251.A O no hydrogen 3.940 N/A LYS 180.A NZ TYR 175.A O no hydrogen 2.800 N/A SER 181.A OG ASP 220.A OD2 no hydrogen 3.223 N/A PHE 183.A N GLY 179.A O no hydrogen 2.922 N/A LEU 184.A N LYS 180.A O no hydrogen 2.913 N/A ARG 185.A N SER 181.A O no hydrogen 2.906 N/A CYS 186.A N SER 182.A O no hydrogen 2.905 N/A CYS 186.A SG SER 182.A O no hydrogen 3.165 N/A ILE 187.A N PHE 183.A O no hydrogen 2.939 N/A ILE 187.A N LEU 184.A O no hydrogen 3.195 N/A THR 188.A N LEU 184.A O no hydrogen 2.910 N/A THR 188.A OG1 HIS 208.A O no hydrogen 2.542 N/A LYS 189.A N THR 188.A OG1 no hydrogen 2.666 N/A SER 190.A OG VAL 206.A O no hydrogen 3.198 N/A TYR 197.A N GLN 195.A O no hydrogen 2.929 N/A SER 203.A OG LYS 202.A O no hydrogen 2.751 N/A TYR 205.A N ASP 220.A O no hydrogen 2.964 N/A GLY 207.A N ALA 218.A O no hydrogen 2.901 N/A HIS 208.A N THR 188.A OG1 no hydrogen 2.768 N/A PHE 209.A N PHE 216.A O no hydrogen 2.924 N/A TYR 211.A N LEU 214.A O no hydrogen 3.020 N/A LEU 214.A N TYR 211.A O no hydrogen 3.030 N/A PHE 216.A N PHE 209.A O no hydrogen 2.912 N/A GLN 217.A N ARG 168.A O no hydrogen 2.937 N/A GLN 217.A NE2 ASP 164.A O no hydrogen 2.760 N/A GLN 217.A NE2 THR 169.A OG1 no hydrogen 2.799 N/A ALA 218.A N GLY 207.A O no hydrogen 2.861 N/A ILE 219.A N LEU 170.A O no hydrogen 2.886 N/A ASP 220.A N TYR 205.A O no hydrogen 2.857 N/A THR 221.A N ILE 172.A O no hydrogen 2.986 N/A THR 221.A OG1 ILE 172.A O no hydrogen 3.011 N/A THR 221.A OG1 SER 239.A OG no hydrogen 3.139 N/A ILE 224.A N GLY 174.A O no hydrogen 3.383 N/A ASP 226.A N TYR 175.A OH no hydrogen 3.348 N/A GLU 231.A N PRO 228.A O no hydrogen 2.881 N/A ASN 233.A ND2 GLU 236.A OE2 no hydrogen 3.563 N/A ASN 234.A ND2 THR 84.A O no hydrogen 3.198 N/A MET 237.A N ASN 233.A O no hydrogen 2.915 N/A SER 239.A OG THR 221.A OG1 no hydrogen 3.139 N/A ILE 240.A N GLU 236.A O no hydrogen 2.950 N/A TYR 241.A N MET 237.A O no hydrogen 2.875 N/A ALA 242.A N GLN 238.A O no hydrogen 2.908 N/A ILE 243.A N SER 239.A O no hydrogen 2.931 N/A ALA 244.A N ILE 240.A O no hydrogen 2.903 N/A HIS 245.A N TYR 241.A O no hydrogen 2.917 N/A ARG 247.A NH1 PRO 165.A O no hydrogen 2.999 N/A ARG 247.A NH1 ASN 166.A O no hydrogen 3.149 N/A SER 248.A OG LEU 246.A O no hydrogen 3.423 N/A CYS 249.A N THR 169.A O no hydrogen 2.914 N/A CYS 249.A SG SER 282.A O no hydrogen 3.758 N/A CYS 249.A SG ALA 321.A O no hydrogen 3.759 N/A VAL 250.A N SER 282.A O no hydrogen 2.903 N/A LEU 251.A N LEU 171.A O no hydrogen 2.888 N/A TYR 252.A N MET 284.A O no hydrogen 2.911 N/A PHE 253.A N CYS 173.A O no hydrogen 2.895 N/A MET 254.A N VAL 286.A O no hydrogen 2.913 N/A GLN 259.A N SER 257.A OG no hydrogen 3.343 N/A CYS 260.A SG PRO 176.A O no hydrogen 3.733 N/A CYS 260.A SG ASN 177.A O no hydrogen 3.451 N/A PHE 262.A N CYS 260.A O no hydrogen 2.671 N/A GLN 267.A N THR 263.A O no hydrogen 2.920 N/A GLN 267.A NE2 ASP 255.A O no hydrogen 3.400 N/A VAL 268.A N ILE 264.A O no hydrogen 2.917 N/A LYS 269.A N GLU 265.A O no hydrogen 2.871 N/A LYS 269.A NZ GLU 265.A OE2 no hydrogen 3.405 N/A LEU 270.A N ALA 266.A O no hydrogen 2.913 N/A PHE 271.A N GLN 267.A O no hydrogen 2.907 N/A HIS 272.A N VAL 268.A O no hydrogen 2.924 N/A HIS 272.A NE2 SER 294.A OG no hydrogen 3.076 N/A SER 273.A N LYS 269.A O no hydrogen 2.863 N/A SER 273.A OG ASP 226.A OD1 no hydrogen 3.214 N/A SER 273.A OG LYS 269.A O no hydrogen 2.494 N/A ILE 274.A N LEU 270.A O no hydrogen 2.939 N/A LYS 275.A N HIS 272.A O no hydrogen 3.318 N/A LEU 277.A N ILE 274.A O no hydrogen 2.974 N/A PHE 278.A N LYS 275.A O no hydrogen 2.930 N/A LYS 281.A N PHE 278.A O no hydrogen 3.209 N/A LYS 281.A NZ ASN 280.A O no hydrogen 3.253 N/A MET 284.A N VAL 250.A O no hydrogen 2.912 N/A VAL 285.A N GLU 302.A O no hydrogen 2.853 N/A VAL 286.A N TYR 252.A O no hydrogen 2.893 N/A ILE 287.A N MET 304.A O no hydrogen 3.320 N/A ASN 288.A ND2 MET 254.A O no hydrogen 3.164 N/A LYS 289.A NZ SER 257.A OG no hydrogen 2.887 N/A SER 294.A N LEU 291.A O no hydrogen 3.312 N/A SER 294.A OG HIS 272.A NE2 no hydrogen 3.076 N/A LYS 296.A N GLU 293.A O no hydrogen 3.218 N/A GLU 297.A N SER 294.A O no hydrogen 3.187 N/A MET 304.A N VAL 285.A O no hydrogen 2.973 N/A THR 305.A OG1 THR 305.A O no hydrogen 2.597 N/A SER 306.A N ILE 287.A O no hydrogen 3.394 N/A SER 306.A OG SER 307.A O no hydrogen 3.477 N/A CYS 308.A SG GLY 179.A O no hydrogen 3.927 N/A CYS 308.A SG ASN 288.A OD1 no hydrogen 3.350 N/A GLN 309.A N SER 307.A OG no hydrogen 3.109 N/A GLU 312.A N GLU 312.A OE1 no hydrogen 2.666 N/A VAL 314.A N LEU 310.A O no hydrogen 2.953 N/A MET 315.A N GLU 311.A O no hydrogen 2.878 N/A GLU 316.A N GLU 312.A O no hydrogen 2.894 N/A VAL 317.A N ASN 313.A O no hydrogen 2.895 N/A ARG 318.A N VAL 314.A O no hydrogen 2.960 N/A ASN 319.A N MET 315.A O no hydrogen 2.889 N/A LYS 320.A N GLU 316.A O no hydrogen 2.906 N/A LYS 320.A NZ GLU 316.A OE2 no hydrogen 3.022 N/A ALA 321.A N VAL 317.A O no hydrogen 2.930 N/A CYS 322.A N ARG 318.A O no hydrogen 2.895 N/A CYS 322.A SG ARG 318.A O no hydrogen 3.194 N/A GLU 323.A N ASN 319.A O no hydrogen 2.921 N/A LYS 324.A N LYS 320.A O no hydrogen 2.906 N/A LEU 325.A N ALA 321.A O no hydrogen 2.922 N/A LEU 326.A N CYS 322.A O no hydrogen 2.896 N/A ALA 327.A N GLU 323.A O no hydrogen 2.904 N/A LYS 337.A N PRO 333.A O no hydrogen 2.918 N/A ASN 338.A N GLU 334.A O no hydrogen 2.910 N/A ASP 346.A N ASP 343.A O no hydrogen 3.306 N/A ARG 349.A N ASP 346.A O no hydrogen 3.328 N/A ARG 349.A NH1 ASP 346.A O no hydrogen 3.165 N/A ILE 356.A N LEU 352.A O no hydrogen 2.931 N/A GLU 357.A N ALA 353.A O no hydrogen 2.890 N/A ALA 358.A N ARG 354.A O no hydrogen 2.925 N/A GLU 359.A N ASP 355.A O no hydrogen 2.888 N/A ASN 360.A N ILE 356.A O no hydrogen 2.901 N/A ASN 360.A ND2 ILE 356.A O no hydrogen 2.861 N/A GLY 362.A N GLU 357.A O no hydrogen 2.401 N/A VAL 365.A N GLY 362.A O no hydrogen 3.423 N/A PHE 366.A N GLY 362.A O no hydrogen 3.164 N/A ASN 369.A ND2 ASP 372.A OD2 no hydrogen 2.762 N/A ASN 369.A ND2 ASN 383.A OD1 no hydrogen 3.554 N/A LYS 371.A NZ TYR 374.A OH no hydrogen 3.470 N/A ASP 372.A N ASN 369.A O no hydrogen 3.399 N/A LYS 373.A N LEU 370.A O no hydrogen 3.366 N/A TYR 374.A N LYS 371.A O no hydrogen 3.427 N/A LEU 376.A N TYR 374.A O no hydrogen 2.864 N/A GLU 380.A N GLU 380.A OE1 no hydrogen 2.449 N/A TRP 381.A N ASP 378.A O no hydrogen 2.966 N/A LYS 382.A N ASP 379.A O no hydrogen 3.225 N/A LYS 382.A NZ ASP 372.A O no hydrogen 3.021 N/A LEU 390.A N LYS 393.A O no hydrogen 2.690 N/A LYS 393.A N LEU 390.A O no hydrogen 2.784 N/A LYS 393.A NZ ASP 391.A O no hydrogen 3.557 N/A ASN 394.A ND2 ASP 397.A OD2 no hydrogen 3.360 N/A VAL 395.A N GLU 388.A O no hydrogen 2.839 N/A LEU 399.A N VAL 395.A O no hydrogen 2.889 N/A LEU 407.A N ILE 403.A O no hydrogen 2.902 N/A GLN 408.A N ALA 404.A O no hydrogen 2.890 N/A ALA 409.A N ALA 405.A O no hydrogen 2.911 N/A LEU 410.A N LYS 406.A O no hydrogen 2.906 N/A GLU 411.A N LEU 407.A O no hydrogen 2.891 N/A GLU 412.A N GLN 408.A O no hydrogen 2.872 N/A GLU 413.A N ALA 409.A O no hydrogen 2.938 N/A GLU 414.A N LEU 410.A O no hydrogen 2.906 N/A GLU 415.A N GLU 411.A O no hydrogen 2.891 N/A LYS 416.A N GLU 412.A O no hydrogen 2.886 N/A LEU 417.A N GLU 413.A O no hydrogen 2.938 N/A GLU 418.A N GLU 414.A O no hydrogen 2.895 N/A ASN 419.A N GLU 415.A O no hydrogen 2.874 N/A GLU 420.A N LYS 416.A O no hydrogen 2.908 N/A GLY 421.A N LEU 417.A O no hydrogen 2.903 N/A PHE 422.A N LEU 417.A O no hydrogen 3.137 N/A