Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8v84_q.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ASN 1.A N SER 4.A OG no hydrogen 3.392 N/A SER 4.A OG ASN 1.A O no hydrogen 2.485 N/A THR 5.A N ASN 1.A O no hydrogen 2.899 N/A THR 5.A OG1 ASN 1.A O no hydrogen 2.956 N/A ARG 6.A N LEU 2.A O no hydrogen 2.892 N/A THR 7.A N THR 3.A O no hydrogen 2.919 N/A THR 7.A OG1 THR 3.A O no hydrogen 3.172 N/A THR 7.A OG1 SER 4.A O no hydrogen 2.529 N/A ARG 8.A N SER 4.A O no hydrogen 2.904 N/A MET 9.A N THR 5.A O no hydrogen 2.888 N/A ILE 10.A N ARG 6.A O no hydrogen 2.912 N/A GLU 11.A N THR 7.A O no hydrogen 2.911 N/A ILE 12.A N ARG 8.A O no hydrogen 2.886 N/A VAL 13.A N MET 9.A O no hydrogen 2.894 N/A LYS 14.A N ILE 10.A O no hydrogen 2.920 N/A VAL 15.A N GLU 11.A O no hydrogen 2.901 N/A LEU 16.A N ILE 12.A O no hydrogen 2.870 N/A GLU 17.A N VAL 13.A O no hydrogen 2.908 N/A ASN 18.A N LYS 14.A O no hydrogen 2.908 N/A GLY 23.A N PHE 19.A O no hydrogen 3.128 N/A ALA 24.A N TYR 32.A OH no hydrogen 3.337 N/A ARG 27.A N ALA 24.A O no hydrogen 3.371 N/A ARG 29.A NH1 LEU 16.A O no hydrogen 3.022 N/A ARG 29.A NH2 LEU 16.A O no hydrogen 2.936 N/A VAL 33.A N ARG 29.A O no hydrogen 2.921 N/A ASP 34.A N GLY 30.A O no hydrogen 2.904 N/A ARG 35.A N GLU 31.A O no hydrogen 2.881 N/A LEU 36.A N TYR 32.A O no hydrogen 2.898 N/A LEU 37.A N VAL 33.A O no hydrogen 2.931 N/A LYS 38.A N ASP 34.A O no hydrogen 2.907 N/A ASP 39.A N ARG 35.A O no hydrogen 2.880 N/A ILE 40.A N LEU 36.A O no hydrogen 2.890 N/A CYS 41.A N LEU 37.A O no hydrogen 2.932 N/A CYS 41.A SG LEU 37.A O no hydrogen 3.206 N/A CYS 41.A SG TYR 46.A O no hydrogen 3.904 N/A GLU 42.A N LYS 38.A O no hydrogen 2.882 N/A TYR 43.A N ASP 39.A O no hydrogen 2.912 N/A GLY 45.A N ILE 40.A O no hydrogen 3.216 N/A ALA 51.A N THR 47.A O no hydrogen 2.923 N/A GLU 52.A N PRO 48.A O no hydrogen 2.870 N/A LYS 53.A N PHE 49.A O no hydrogen 2.930 N/A LEU 54.A N LEU 50.A O no hydrogen 2.901 N/A PHE 55.A N ALA 51.A O no hydrogen 2.900 N/A ASN 56.A N GLU 52.A O no hydrogen 2.892 N/A LEU 57.A N LYS 53.A O no hydrogen 2.920 N/A PHE 58.A N LEU 54.A O no hydrogen 2.896 N/A GLU 62.A N SER 59.A OG no hydrogen 3.288 N/A ALA 63.A N SER 59.A O no hydrogen 2.857 N/A MET 64.A N PRO 60.A O no hydrogen 2.933 N/A GLU 65.A N ALA 61.A O no hydrogen 2.935 N/A PHE 66.A N GLU 62.A O no hydrogen 2.841 N/A PHE 67.A N ALA 63.A O no hydrogen 2.922 N/A GLU 68.A N MET 64.A O no hydrogen 2.928 N/A ALA 69.A N GLU 65.A O no hydrogen 2.880 N/A ASN 70.A N PHE 66.A O no hydrogen 2.911 N/A GLU 71.A N PHE 67.A O no hydrogen 2.925 N/A ILE 72.A N GLU 68.A O no hydrogen 2.903 N/A THR 77.A OG1 GLN 135.A O no hydrogen 2.941 N/A ILE 78.A N LEU 112.A O no hydrogen 2.899 N/A ARG 79.A N ILE 133.A O no hydrogen 2.922 N/A ARG 79.A NE ARG 79.A O no hydrogen 2.884 N/A ASN 81.A N HIS 131.A O no hydrogen 2.896 N/A LEU 83.A N ASN 81.A OD1 no hydrogen 3.328 N/A LYS 84.A N ASN 81.A O no hydrogen 3.421 N/A LYS 84.A NZ GLY 130.A O no hydrogen 3.477 N/A LYS 84.A NZ ARG 197.A O no hydrogen 3.533 N/A LEU 90.A N ARG 86.A O no hydrogen 2.928 N/A ALA 91.A N ARG 87.A O no hydrogen 2.868 N/A GLN 92.A N ARG 88.A O no hydrogen 2.927 N/A THR 93.A N ASP 89.A O no hydrogen 2.866 N/A THR 93.A OG1 ASP 89.A O no hydrogen 2.770 N/A LEU 94.A N LEU 90.A O no hydrogen 2.959 N/A VAL 95.A N ALA 91.A O no hydrogen 2.884 N/A ASN 96.A N GLN 92.A O no hydrogen 2.889 N/A ARG 97.A N THR 93.A O no hydrogen 2.909 N/A GLY 98.A N LEU 94.A O no hydrogen 2.909 N/A GLY 98.A N VAL 95.A O no hydrogen 3.133 N/A VAL 99.A N LEU 94.A O no hydrogen 2.622 N/A ILE 104.A N GLY 111.A O no hydrogen 3.154 N/A GLY 105.A N PRO 103.A O no hydrogen 2.989 N/A THR 108.A OG1 ILE 104.A O no hydrogen 3.167 N/A LEU 112.A N ILE 78.A O no hydrogen 2.902 N/A GLN 113.A N GLN 102.A O no hydrogen 2.500 N/A ILE 114.A N ILE 76.A O no hydrogen 2.905 N/A SER 117.A N ASP 116.A OD1 no hydrogen 2.621 N/A THR 124.A N PRO 120.A O no hydrogen 2.924 N/A THR 124.A N ILE 121.A O no hydrogen 3.354 N/A THR 124.A OG1 GLU 126.A OE1 no hydrogen 2.576 N/A ALA 129.A N GLU 126.A O no hydrogen 3.217 N/A GLY 130.A N TYR 127.A O no hydrogen 3.300 N/A HIS 131.A N GLU 126.A O no hydrogen 3.116 N/A ILE 133.A N ARG 79.A O no hydrogen 2.895 N/A GLN 135.A NE2 GLY 163.A O no hydrogen 2.952 N/A SER 138.A OG ASP 344.A OD2 no hydrogen 2.816 N/A PHE 140.A N ALA 136.A O no hydrogen 2.917 N/A LEU 141.A N SER 138.A O no hydrogen 3.276 N/A ILE 144.A N PHE 140.A O no hydrogen 3.084 N/A ALA 145.A N LEU 141.A O no hydrogen 2.899 N/A LEU 146.A N PRO 142.A O no hydrogen 2.894 N/A ASP 147.A N VAL 143.A O no hydrogen 2.919 N/A HIS 149.A N GLU 152.A OE1 no hydrogen 3.101 N/A ARG 153.A NH2 GLY 218.A O no hydrogen 3.438 N/A ILE 154.A N CYS 177.A O no hydrogen 2.906 N/A LEU 155.A N ARG 222.A O no hydrogen 2.919 N/A ASP 156.A N PHE 179.A O no hydrogen 2.879 N/A MET 157.A N LEU 224.A O no hydrogen 2.915 N/A THR 165.A OG1 ASP 156.A OD2 no hydrogen 2.424 N/A THR 166.A N GLY 162.A O no hydrogen 2.899 N/A THR 166.A OG1 GLY 162.A O no hydrogen 2.918 N/A THR 166.A OG1 GLY 163.A O no hydrogen 2.660 N/A TYR 167.A N GLY 163.A O no hydrogen 2.925 N/A ILE 168.A N LYS 164.A O no hydrogen 2.893 N/A SER 169.A N THR 165.A O no hydrogen 2.914 N/A ALA 170.A N THR 166.A O no hydrogen 2.883 N/A MET 171.A N TYR 167.A O no hydrogen 2.930 N/A MET 172.A N ILE 168.A O no hydrogen 2.908 N/A LYS 173.A N SER 169.A O no hydrogen 2.887 N/A CYS 177.A N GLU 152.A O no hydrogen 2.904 N/A PHE 179.A N ILE 154.A O no hydrogen 2.915 N/A ALA 180.A N ILE 204.A O no hydrogen 2.883 N/A ASN 181.A N ASP 156.A O no hydrogen 2.920 N/A ASN 181.A ND2 TYR 208.A O no hydrogen 2.746 N/A ASP 182.A N CYS 206.A O no hydrogen 2.916 N/A SER 186.A N ASN 184.A OD1 no hydrogen 3.085 N/A THR 188.A N ASN 184.A O no hydrogen 2.884 N/A THR 188.A OG1 ASN 184.A O no hydrogen 3.035 N/A THR 188.A OG1 LYS 185.A O no hydrogen 2.453 N/A LYS 189.A N LYS 185.A O no hydrogen 2.921 N/A SER 190.A N SER 186.A O no hydrogen 2.897 N/A SER 190.A OG SER 186.A O no hydrogen 3.009 N/A LEU 191.A N ARG 187.A O no hydrogen 2.885 N/A ILE 192.A N THR 188.A O no hydrogen 2.901 N/A ALA 193.A N LYS 189.A O no hydrogen 2.907 N/A ASN 194.A N SER 190.A O no hydrogen 2.912 N/A ILE 195.A N LEU 191.A O no hydrogen 2.899 N/A HIS 196.A N ILE 192.A O no hydrogen 2.921 N/A ARG 197.A N ALA 193.A O no hydrogen 2.888 N/A LEU 198.A N ASN 194.A O no hydrogen 2.929 N/A CYS 200.A N ILE 195.A O no hydrogen 3.167 N/A THR 203.A OG1 ASN 202.A OD1 no hydrogen 3.463 N/A ILE 204.A N VAL 178.A O no hydrogen 2.901 N/A CYS 206.A N ALA 180.A O no hydrogen 2.896 N/A TYR 208.A N ASN 181.A OD1 no hydrogen 2.633 N/A TYR 208.A N ASP 182.A O no hydrogen 3.240 N/A GLU 212.A N ASP 209.A O no hydrogen 3.182 N/A VAL 216.A N GLU 212.A O no hydrogen 3.289 N/A ILE 217.A N PHE 213.A O no hydrogen 2.926 N/A GLY 219.A N SER 267.A O no hydrogen 2.796 N/A PHE 220.A N SER 267.A O no hydrogen 3.365 N/A ARG 222.A N ARG 153.A O no hydrogen 2.911 N/A ARG 222.A NH1 LEU 146.A O no hydrogen 2.816 N/A ILE 223.A N VAL 277.A O no hydrogen 2.925 N/A LEU 224.A N LEU 155.A O no hydrogen 2.881 N/A LEU 225.A N VAL 279.A O no hydrogen 2.890 N/A ALA 227.A N SER 281.A O no hydrogen 2.896 N/A CYS 229.A SG ALA 227.A O no hydrogen 3.550 N/A SER 230.A OG SER 284.A OG no hydrogen 2.809 N/A THR 232.A OG1 SER 284.A OG no hydrogen 2.489 N/A VAL 234.A N GLY 231.A O no hydrogen 3.313 N/A LYS 237.A NZ ASP 344.A OD2 no hydrogen 3.183 N/A ASP 238.A N VAL 234.A O no hydrogen 2.914 N/A VAL 241.A N ASP 238.A O no hydrogen 3.043 N/A LYS 242.A NZ PHE 44.A O no hydrogen 3.264 N/A SER 244.A N SER 240.A O no hydrogen 2.909 N/A SER 244.A OG SER 240.A O no hydrogen 2.560 N/A SER 244.A OG VAL 241.A O no hydrogen 2.983 N/A ARG 245.A N VAL 241.A O no hydrogen 2.903 N/A ARG 245.A NE SER 230.A O no hydrogen 2.861 N/A PHE 250.A N THR 246.A O no hydrogen 2.941 N/A ILE 251.A N GLU 247.A O no hydrogen 2.902 N/A ILE 251.A N LYS 248.A O no hydrogen 3.300 N/A GLN 252.A N LYS 248.A O no hydrogen 2.899 N/A ILE 253.A N ASP 249.A O no hydrogen 2.911 N/A LEU 256.A N GLN 252.A O no hydrogen 3.406 N/A GLN 257.A N ILE 253.A O no hydrogen 2.913 N/A GLN 257.A NE2 GLU 289.A OE1 no hydrogen 3.542 N/A LYS 258.A N PRO 254.A O no hydrogen 2.887 N/A GLN 259.A N HIS 255.A O no hydrogen 2.936 N/A GLN 259.A NE2 HIS 255.A NE2 no hydrogen 3.077 N/A LEU 260.A N LEU 256.A O no hydrogen 2.902 N/A LEU 261.A N GLN 257.A O no hydrogen 2.911 N/A LEU 262.A N LYS 258.A O no hydrogen 2.897 N/A SER 263.A N GLN 259.A O no hydrogen 2.928 N/A SER 263.A OG ARG 211.A O no hydrogen 3.200 N/A SER 263.A OG GLN 259.A O no hydrogen 3.092 N/A ALA 264.A N LEU 260.A O no hydrogen 2.895 N/A ILE 265.A N LEU 261.A O no hydrogen 2.900 N/A ASP 266.A N LEU 262.A O no hydrogen 2.918 N/A SER 267.A N SER 263.A O no hydrogen 2.898 N/A VAL 268.A N ALA 264.A O no hydrogen 2.904 N/A ASP 269.A N PHE 220.A O no hydrogen 3.111 N/A CYS 270.A SG ASN 271.A OD1 no hydrogen 3.514 N/A CYS 270.A SG ILE 354.A O no hydrogen 3.906 N/A ASN 271.A N ASP 269.A OD1 no hydrogen 3.156 N/A SER 272.A OG ASP 221.A OD2 no hydrogen 2.407 N/A GLY 275.A N SER 272.A O no hydrogen 3.185 N/A VAL 277.A N ASP 221.A O no hydrogen 3.433 N/A ILE 278.A N PHE 351.A O no hydrogen 2.893 N/A VAL 279.A N ILE 223.A O no hydrogen 2.892 N/A TYR 280.A N ALA 349.A O no hydrogen 2.909 N/A TYR 280.A OH GLU 289.A O no hydrogen 3.367 N/A SER 281.A N LEU 225.A O no hydrogen 2.906 N/A SER 281.A OG LEU 225.A O no hydrogen 3.311 N/A THR 282.A N PHE 347.A O no hydrogen 2.887 N/A THR 282.A OG1 ASP 290.A OD1 no hydrogen 2.346 N/A CYS 283.A SG ASP 226.A OD1 no hydrogen 3.611 N/A SER 284.A OG SER 230.A OG no hydrogen 2.809 N/A SER 284.A OG THR 232.A OG1 no hydrogen 2.489 N/A VAL 285.A N THR 232.A OG1 no hydrogen 2.888 N/A ALA 286.A N SER 284.A OG no hydrogen 3.067 N/A ASP 290.A N ALA 286.A O no hydrogen 2.933 N/A ASP 290.A N VAL 287.A O no hydrogen 3.288 N/A GLU 291.A N VAL 287.A O no hydrogen 2.888 N/A GLU 291.A N GLU 288.A O no hydrogen 3.239 N/A ALA 292.A N GLU 288.A O no hydrogen 2.887 N/A ASP 295.A N GLU 291.A O no hydrogen 2.925 N/A TYR 296.A N ALA 292.A O no hydrogen 2.883 N/A ALA 297.A N VAL 293.A O no hydrogen 2.924 N/A LEU 298.A N ILE 294.A O no hydrogen 2.903 N/A ARG 299.A N ASP 295.A O no hydrogen 2.917 N/A LYS 300.A N TYR 296.A O no hydrogen 2.893 N/A ARG 301.A N ALA 297.A O no hydrogen 2.918 N/A ARG 301.A NH1 LYS 300.A O no hydrogen 3.333 N/A VAL 304.A N ARG 301.A O no hydrogen 3.087 N/A LYS 305.A N GLN 352.A O no hydrogen 2.913 N/A VAL 307.A N LYS 350.A O no hydrogen 2.911 N/A GLY 310.A N ASP 308.A OD1 no hydrogen 3.164 N/A GLY 314.A N TYR 341.A OH no hydrogen 2.802 N/A LYS 315.A N ARG 335.A O no hydrogen 3.249 N/A THR 319.A OG1 THR 319.A O no hydrogen 2.508 N/A THR 319.A OG1 HIS 327.A O no hydrogen 2.449 N/A TYR 321.A N LYS 324.A O no hydrogen 3.150 N/A LYS 324.A N TYR 321.A O no hydrogen 2.708 N/A PHE 326.A N THR 319.A O no hydrogen 2.716 N/A SER 329.A N HIS 327.A ND1 no hydrogen 3.044 N/A VAL 330.A N HIS 327.A O no hydrogen 3.288 N/A LEU 332.A N SER 329.A O no hydrogen 3.306 N/A ALA 333.A N VAL 330.A O no hydrogen 3.147 N/A ARG 335.A N LYS 315.A O no hydrogen 2.612 N/A ARG 335.A NH2 VAL 285.A O no hydrogen 3.123 N/A THR 340.A N TYR 337.A O no hydrogen 3.154 N/A THR 340.A OG1 TYR 337.A O no hydrogen 2.522 N/A GLY 345.A N GLY 233.A O no hydrogen 2.886 N/A PHE 347.A N THR 282.A O no hydrogen 2.920 N/A ALA 349.A N TYR 280.A O no hydrogen 2.892 N/A PHE 351.A N ILE 278.A O no hydrogen 2.877 N/A GLN 352.A N LYS 305.A O no hydrogen 2.892 N/A LYS 353.A N GLY 276.A O no hydrogen 2.927 N/A LYS 353.A NZ VAL 268.A O no hydrogen 2.461 N/A ILE 354.A N ASN 303.A O no hydrogen 2.891 N/A