Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8w8d_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): MET 1.A N ASP 48.A O no hydrogen 2.954 N/A LEU 6.A N ASN 2.A O no hydrogen 2.898 N/A LYS 7.A N LEU 3.A O no hydrogen 2.901 N/A LYS 7.A NZ ASP 77.A OD2 no hydrogen 2.899 N/A ASN 8.A N GLU 5.A O no hydrogen 3.053 N/A THR 9.A N LEU 6.A O no hydrogen 3.273 N/A THR 9.A OG1 LEU 6.A O no hydrogen 2.911 N/A LEU 14.A N PRO 10.A O no hydrogen 3.234 N/A LEU 14.A N VAL 11.A O no hydrogen 3.352 N/A THR 16.A N SER 12.A O no hydrogen 3.348 N/A THR 16.A OG1 GLU 13.A O no hydrogen 2.689 N/A LEU 17.A N GLU 13.A O no hydrogen 2.898 N/A GLY 18.A N LEU 14.A O no hydrogen 2.919 N/A GLU 19.A N ILE 15.A O no hydrogen 2.925 N/A ASN 20.A N THR 16.A O no hydrogen 2.890 N/A MET 21.A N LEU 17.A O no hydrogen 2.929 N/A GLY 22.A N GLU 19.A O no hydrogen 3.137 N/A LEU 23.A N GLY 18.A O no hydrogen 2.818 N/A ARG 28.A NH2 ASN 25.A O no hydrogen 2.525 N/A GLN 32.A N GLN 32.A OE1 no hydrogen 2.680 N/A ILE 35.A N LYS 31.A O no hydrogen 2.971 N/A PHE 36.A N GLN 32.A O no hydrogen 2.921 N/A ALA 37.A N ASP 33.A O no hydrogen 2.870 N/A ILE 38.A N ILE 34.A O no hydrogen 2.911 N/A LEU 39.A N ILE 35.A O no hydrogen 2.914 N/A LYS 40.A N PHE 36.A O no hydrogen 2.928 N/A GLN 41.A N ALA 37.A O no hydrogen 2.894 N/A HIS 42.A N ILE 38.A O no hydrogen 2.974 N/A SER 45.A OG ASP 48.A OD2 no hydrogen 3.057 N/A PHE 50.A N MET 1.A O no hydrogen 2.508 N/A GLY 51.A N GLY 99.A O no hydrogen 2.904 N/A VAL 54.A N ARG 66.A O no hydrogen 2.904 N/A LEU 55.A N ASP 95.A O no hydrogen 2.777 N/A GLU 56.A N PHE 64.A O no hydrogen 2.892 N/A LEU 58.A N PHE 62.A O no hydrogen 3.015 N/A GLN 59.A N GLN 59.A OE1 no hydrogen 2.420 N/A GLY 61.A N LEU 58.A O no hydrogen 3.208 N/A GLY 63.A N VAL 81.A O no hydrogen 3.480 N/A PHE 64.A N GLU 56.A O no hydrogen 2.911 N/A LEU 65.A N ILE 79.A O no hydrogen 2.910 N/A ARG 66.A N VAL 54.A O no hydrogen 2.898 N/A SER 67.A OG SER 70.A OG no hydrogen 3.008 N/A SER 70.A OG SER 67.A O no hydrogen 3.256 N/A SER 70.A OG SER 67.A OG no hydrogen 3.008 N/A SER 71.A N ALA 68.A O no hydrogen 3.075 N/A SER 71.A OG SER 71.A O no hydrogen 2.236 N/A SER 71.A OG ALA 229.A O no hydrogen 2.861 N/A TYR 72.A N SER 67.A O no hydrogen 3.322 N/A LEU 73.A N SER 70.A O no hydrogen 3.243 N/A GLY 75.A N ASP 78.A OD2 no hydrogen 2.842 N/A ASP 78.A N GLY 75.A O no hydrogen 3.340 N/A TYR 80.A N PHE 111.A O no hydrogen 2.900 N/A VAL 81.A N GLY 63.A O no hydrogen 2.901 N/A GLN 85.A N SER 82.A O no hydrogen 3.252 N/A GLN 85.A NE2 SER 82.A OG no hydrogen 2.389 N/A ARG 87.A N PRO 83.A O no hydrogen 2.913 N/A ARG 88.A N SER 84.A O no hydrogen 2.899 N/A PHE 89.A N GLN 85.A O no hydrogen 2.930 N/A GLY 94.A N LEU 55.A O no hydrogen 3.068 N/A THR 96.A N ASN 120.A OD1 no hydrogen 3.504 N/A ILE 97.A N GLY 53.A O no hydrogen 2.938 N/A SER 98.A N GLU 118.A O no hydrogen 2.909 N/A GLY 99.A N GLY 51.A O no hydrogen 3.346 N/A ARG 102.A N ALA 112.A O no hydrogen 2.450 N/A GLU 108.A N LYS 105.A O no hydrogen 3.258 N/A ALA 112.A N ARG 102.A O no hydrogen 3.105 N/A LEU 114.A N LYS 100.A O no hydrogen 2.714 N/A LYS 115.A N LYS 100.A O no hydrogen 3.280 N/A ASN 117.A N SER 98.A O no hydrogen 2.707 N/A GLU 118.A N SER 98.A O no hydrogen 2.909 N/A VAL 119.A N ASP 122.A O no hydrogen 3.172 N/A ASN 120.A N THR 96.A O no hydrogen 3.069 N/A ASP 122.A N VAL 119.A O no hydrogen 2.939 N/A LYS 123.A N ASP 122.A OD1 no hydrogen 3.241 N/A ASN 126.A N LYS 123.A O no hydrogen 2.990 N/A ALA 127.A N ASN 126.A OD1 no hydrogen 3.006 N/A LYS 130.A NZ ASP 122.A OD2 no hydrogen 3.540 N/A ASN 135.A N LEU 132.A O no hydrogen 3.137 N/A THR 137.A OG1 PRO 138.A O no hydrogen 3.394 N/A LEU 145.A N ILE 168.A O no hydrogen 3.019 N/A ARG 146.A NH2 GLU 373.A OE2 no hydrogen 3.304 N/A MET 147.A N ASP 163.A OD2 no hydrogen 3.410 N/A GLU 148.A N ASP 163.A OD2 no hydrogen 3.135 N/A ARG 149.A NH1 ASN 198.A O no hydrogen 3.235 N/A ARG 160.A N ASP 156.A O no hydrogen 3.199 N/A ARG 160.A NE ASP 156.A OD1 no hydrogen 3.008 N/A VAL 161.A N LEU 157.A O no hydrogen 3.006 N/A ASP 163.A N ALA 159.A O no hydrogen 3.121 N/A ALA 165.A N LEU 162.A O no hydrogen 3.376 N/A SER 166.A N LEU 162.A O no hydrogen 3.119 N/A SER 166.A OG SER 166.A O no hydrogen 2.308 N/A ARG 170.A N SER 143.A O no hydrogen 3.337 N/A ARG 173.A NE ALA 301.A O no hydrogen 3.333 N/A ARG 173.A NH2 ALA 301.A O no hydrogen 2.826 N/A GLY 174.A N ILE 312.A O no hydrogen 3.308 N/A LEU 175.A N MET 338.A O no hydrogen 2.887 N/A ILE 176.A N ALA 314.A O no hydrogen 3.234 N/A VAL 177.A N LEU 340.A O no hydrogen 2.890 N/A ALA 178.A N ALA 316.A O no hydrogen 3.333 N/A LEU 187.A N GLY 183.A O no hydrogen 3.496 N/A LEU 188.A N LYS 184.A O no hydrogen 2.929 N/A GLN 189.A N THR 185.A O no hydrogen 2.924 N/A GLN 189.A NE2 GLU 218.A OE1 no hydrogen 3.256 N/A ASN 190.A N MET 186.A O no hydrogen 2.922 N/A ASN 190.A ND2 GLU 155.A O no hydrogen 3.131 N/A ILE 191.A N LEU 187.A O no hydrogen 2.885 N/A ALA 192.A N LEU 188.A O no hydrogen 2.934 N/A GLN 193.A N GLN 189.A O no hydrogen 2.909 N/A SER 194.A N ASN 190.A O no hydrogen 2.913 N/A SER 194.A OG MET 147.A O no hydrogen 2.839 N/A ILE 195.A N ILE 191.A O no hydrogen 2.950 N/A ALA 196.A N ALA 192.A O no hydrogen 2.918 N/A TYR 197.A N GLN 193.A O no hydrogen 2.887 N/A ASN 198.A N SER 194.A O no hydrogen 2.927 N/A HIS 199.A N ILE 195.A O no hydrogen 2.936 N/A CYS 202.A N HIS 199.A O no hydrogen 3.447 N/A VAL 203.A N ASP 259.A O no hydrogen 3.216 N/A MET 205.A N ILE 261.A O no hydrogen 3.252 N/A VAL 206.A N GLU 226.A O no hydrogen 3.114 N/A LEU 207.A N LEU 263.A O no hydrogen 2.906 N/A LEU 208.A N VAL 228.A O no hydrogen 3.309 N/A ILE 209.A N ASP 265.A OD2 no hydrogen 2.612 N/A GLU 214.A N GLU 214.A OE1 no hydrogen 2.849 N/A GLU 215.A N GLU 215.A OE1 no hydrogen 2.500 N/A VAL 216.A N ARG 212.A O no hydrogen 3.300 N/A THR 217.A N PRO 213.A O no hydrogen 2.894 N/A THR 217.A OG1 PRO 213.A O no hydrogen 3.219 N/A THR 217.A OG1 GLU 214.A O no hydrogen 2.608 N/A GLU 218.A N GLU 214.A O no hydrogen 2.940 N/A MET 219.A N GLU 215.A O no hydrogen 2.874 N/A GLN 220.A N VAL 216.A O no hydrogen 2.915 N/A ARG 221.A N THR 217.A O no hydrogen 2.906 N/A LEU 222.A N GLU 218.A O no hydrogen 2.926 N/A GLU 226.A N GLU 226.A OE1 no hydrogen 2.458 N/A VAL 228.A N VAL 206.A O no hydrogen 3.051 N/A SER 230.A N LEU 208.A O no hydrogen 3.222 N/A THR 231.A OG1 ASP 233.A OD2 no hydrogen 3.054 N/A THR 231.A OG1 GLU 234.A OE1 no hydrogen 2.404 N/A ASP 233.A N THR 231.A OG1 no hydrogen 3.392 N/A GLU 234.A N GLU 234.A OE1 no hydrogen 2.720 N/A ARG 238.A N PRO 235.A O no hydrogen 3.272 N/A ARG 238.A NH1 TYR 72.A O no hydrogen 2.611 N/A ARG 238.A NH1 GLN 241.A OE1 no hydrogen 3.214 N/A ARG 238.A NH2 SER 71.A O no hydrogen 2.279 N/A VAL 240.A N ALA 236.A O no hydrogen 2.929 N/A GLN 241.A N SER 237.A O no hydrogen 2.892 N/A GLN 241.A NE2 GLU 56.A OE1 no hydrogen 2.744 N/A VAL 242.A N ARG 238.A O no hydrogen 2.935 N/A ALA 243.A N HIS 239.A O no hydrogen 2.932 N/A GLU 244.A N VAL 240.A O no hydrogen 2.919 N/A MET 245.A N GLN 241.A O no hydrogen 2.936 N/A VAL 246.A N VAL 242.A O no hydrogen 2.918 N/A ILE 247.A N ALA 243.A O no hydrogen 2.945 N/A GLU 248.A N GLU 244.A O no hydrogen 2.903 N/A LYS 249.A N MET 245.A O no hydrogen 2.906 N/A ALA 250.A N VAL 246.A O no hydrogen 2.939 N/A LYS 251.A N ILE 247.A O no hydrogen 2.922 N/A ARG 252.A N GLU 248.A O no hydrogen 2.927 N/A LEU 253.A N LYS 249.A O no hydrogen 2.925 N/A VAL 254.A N ALA 250.A O no hydrogen 2.894 N/A GLU 255.A N LYS 251.A O no hydrogen 2.953 N/A HIS 256.A N LEU 253.A O no hydrogen 3.118 N/A LYS 257.A N VAL 254.A O no hydrogen 3.118 N/A LYS 258.A NZ HIS 256.A O no hydrogen 2.362 N/A VAL 260.A N SER 309.A O no hydrogen 2.913 N/A ILE 261.A N VAL 203.A O no hydrogen 2.966 N/A ILE 262.A N THR 311.A O no hydrogen 2.896 N/A LEU 263.A N MET 205.A O no hydrogen 3.103 N/A LEU 264.A N ILE 313.A O no hydrogen 2.901 N/A ASP 265.A N LEU 207.A O no hydrogen 3.018 N/A SER 266.A N ASP 265.A OD1 no hydrogen 2.553 N/A ILE 267.A N THR 315.A O no hydrogen 3.148 N/A ARG 269.A N SER 266.A OG no hydrogen 3.392 N/A ALA 271.A N ILE 267.A O no hydrogen 2.909 N/A ARG 272.A N THR 268.A O no hydrogen 2.904 N/A ALA 273.A N ARG 269.A O no hydrogen 2.909 N/A TYR 274.A N LEU 270.A O no hydrogen 2.909 N/A ASN 275.A N ALA 271.A O no hydrogen 2.893 N/A THR 276.A N ARG 272.A O no hydrogen 2.908 N/A THR 276.A OG1 ARG 272.A O no hydrogen 2.826 N/A VAL 277.A N ALA 273.A O no hydrogen 2.918 N/A VAL 278.A N TYR 274.A O no hydrogen 2.957 N/A ASN 289.A N ASP 287.A OD1 no hydrogen 3.128 N/A ALA 290.A N ASP 287.A O no hydrogen 3.320 N/A LEU 291.A N ALA 288.A O no hydrogen 3.396 N/A HIS 292.A N ASN 289.A O no hydrogen 3.434 N/A ARG 296.A N HIS 292.A O no hydrogen 3.353 N/A PHE 297.A N ARG 293.A O no hydrogen 3.516 N/A PHE 298.A N PRO 294.A O no hydrogen 3.059 N/A GLY 299.A N LYS 295.A O no hydrogen 2.601 N/A ALA 300.A N PHE 297.A O no hydrogen 2.946 N/A ARG 302.A N LEU 310.A O no hydrogen 3.272 N/A ARG 302.A NH2 GLY 299.A O no hydrogen 3.203 N/A ASN 303.A ND2 HIS 140.A O no hydrogen 3.288 N/A VAL 304.A N GLY 308.A O no hydrogen 3.135 N/A GLU 305.A N THR 137.A O no hydrogen 3.357 N/A GLY 307.A N VAL 304.A O no hydrogen 3.273 N/A SER 309.A N LYS 258.A O no hydrogen 3.174 N/A SER 309.A OG ASP 259.A OD1 no hydrogen 3.316 N/A LEU 310.A N ARG 302.A O no hydrogen 3.171 N/A THR 311.A N VAL 260.A O no hydrogen 2.928 N/A THR 311.A OG1 GLN 172.A O no hydrogen 3.090 N/A ILE 312.A N GLN 172.A O no hydrogen 3.502 N/A ILE 313.A N ILE 262.A O no hydrogen 2.911 N/A ALA 314.A N GLY 174.A O no hydrogen 3.329 N/A THR 315.A OG1 ASP 265.A O no hydrogen 3.200 N/A ALA 316.A N ILE 176.A O no hydrogen 2.789 N/A SER 322.A OG ASP 325.A OD2 no hydrogen 2.211 N/A VAL 327.A N LYS 323.A O no hydrogen 2.933 N/A ILE 328.A N MET 324.A O no hydrogen 2.908 N/A TYR 329.A N ASP 325.A O no hydrogen 2.897 N/A GLU 330.A N GLU 326.A O no hydrogen 2.903 N/A GLU 331.A N VAL 327.A O no hydrogen 2.930 N/A PHE 332.A N ILE 328.A O no hydrogen 3.067 N/A LYS 333.A NZ GLU 330.A OE1 no hydrogen 3.203 N/A THR 335.A N PHE 332.A O no hydrogen 3.399 N/A THR 335.A OG1 PHE 332.A O no hydrogen 2.356 N/A ASN 337.A N ARG 173.A O no hydrogen 2.937 N/A LEU 340.A N LEU 175.A O no hydrogen 2.926 N/A HIS 341.A ND1 ARG 359.A O no hydrogen 2.833 N/A LEU 342.A N VAL 177.A O no hydrogen 3.153 N/A ALA 347.A N SER 343.A O no hydrogen 3.248 N/A GLU 348.A N ARG 344.A O no hydrogen 2.924 N/A LYS 349.A N ILE 346.A O no hydrogen 3.172 N/A ARG 350.A N ALA 347.A O no hydrogen 3.353 N/A ASP 356.A N HIS 341.A O no hydrogen 3.258 N/A TYR 357.A OH LEU 164.A O no hydrogen 2.640 N/A ASN 358.A N ASP 356.A OD1 no hydrogen 3.335 N/A ARG 359.A N ASP 356.A O no hydrogen 3.136 N/A SER 360.A OG GLU 339.A O no hydrogen 3.251 N/A LEU 367.A N LYS 364.A O no hydrogen 3.404 N/A LEU 368.A N GLU 365.A O no hydrogen 3.138 N/A THR 369.A N GLU 365.A O no hydrogen 3.168 N/A THR 369.A OG1 THR 370.A O no hydrogen 3.371 N/A THR 370.A OG1 GLU 373.A OE2 no hydrogen 3.107 N/A GLN 371.A N GLN 371.A OE1 no hydrogen 2.725 N/A GLU 372.A N GLU 372.A OE2 no hydrogen 2.327 N/A LEU 374.A N THR 370.A O no hydrogen 2.860 N/A GLN 375.A N GLN 371.A O no hydrogen 2.916 N/A LYS 376.A N GLU 372.A O no hydrogen 2.955 N/A MET 377.A N GLU 373.A O no hydrogen 2.883 N/A TRP 378.A N LEU 374.A O no hydrogen 2.891 N/A ILE 379.A N GLN 375.A O no hydrogen 2.921 N/A LEU 380.A N LYS 376.A O no hydrogen 2.959 N/A ARG 381.A N MET 377.A O no hydrogen 2.868 N/A LYS 382.A N TRP 378.A O no hydrogen 2.902 N/A ILE 383.A N ILE 379.A O no hydrogen 2.947 N/A ILE 384.A N LEU 380.A O no hydrogen 2.902 N/A HIS 385.A N ARG 381.A O no hydrogen 2.898 N/A GLY 388.A N ASP 391.A OD2 no hydrogen 2.894 N/A ALA 392.A N GLY 388.A O no hydrogen 3.174 N/A MET 393.A N GLU 389.A O no hydrogen 2.933 N/A GLU 394.A N ILE 390.A O no hydrogen 2.903 N/A PHE 395.A N ASP 391.A O no hydrogen 2.904 N/A LEU 396.A N ALA 392.A O no hydrogen 2.907 N/A ILE 397.A N MET 393.A O no hydrogen 2.941 N/A ASN 398.A N GLU 394.A O no hydrogen 2.881 N/A LYS 399.A N PHE 395.A O no hydrogen 2.922 N/A LEU 400.A N LEU 396.A O no hydrogen 2.908 N/A THR 403.A OG1 GLU 411.A OE1 no hydrogen 2.435 N/A LYS 404.A NZ ASP 407.A OD1 no hydrogen 2.820 N/A THR 405.A OG1 GLU 148.A OE2 no hydrogen 3.473 N/A ASP 408.A N THR 405.A O no hydrogen 3.179 N/A GLU 411.A N ASP 407.A O no hydrogen 3.318 N/A MET 412.A N ASP 408.A O no hydrogen 3.077 N/A MET 413.A N PHE 409.A O no hydrogen 2.565 N/A