Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8wv8_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): MET 4.A N LEU 19.A O no hydrogen 3.370 N/A THR 6.A N ASP 12.A OD1 no hydrogen 3.482 N/A THR 6.A OG1 ASP 12.A OD1 no hydrogen 3.451 N/A PHE 11.A N ILE 8.A O no hydrogen 2.981 N/A ASP 13.A N GLY 10.A O no hydrogen 3.244 N/A ILE 14.A N GLY 10.A O no hydrogen 3.106 N/A SER 15.A N PHE 11.A O no hydrogen 3.141 N/A SER 15.A OG PHE 11.A O no hydrogen 2.710 N/A SER 15.A OG GLY 18.A O no hydrogen 2.950 N/A HIS 16.A ND1 SER 198.A OG no hydrogen 2.651 N/A GLY 17.A N ASP 12.A O no hydrogen 2.625 N/A ILE 21.A N ALA 2.A O no hydrogen 2.707 N/A THR 25.A N THR 147.A O no hydrogen 2.747 N/A LEU 26.A N ASN 172.A O no hydrogen 3.038 N/A VAL 27.A N MET 149.A O no hydrogen 2.691 N/A SER 28.A N VAL 174.A O no hydrogen 3.044 N/A SER 28.A OG ILE 160.A O no hydrogen 3.239 N/A THR 30.A OG1 GLU 156.A OE2 no hydrogen 2.614 N/A THR 33.A OG1 THR 30.A O no hydrogen 2.508 N/A LYS 35.A NZ THR 30.A O no hydrogen 2.476 N/A LYS 35.A NZ THR 33.A OG1 no hydrogen 3.111 N/A THR 36.A OG1 ASP 114.A OD2 no hydrogen 2.589 N/A PHE 38.A N GLY 34.A O no hydrogen 3.394 N/A SER 39.A OG THR 36.A O no hydrogen 2.354 N/A ILE 40.A N THR 36.A O no hydrogen 3.033 N/A GLN 41.A N LEU 37.A O no hydrogen 3.073 N/A PHE 42.A N PHE 38.A O no hydrogen 2.804 N/A LEU 43.A N ILE 40.A O no hydrogen 2.985 N/A TYR 44.A N ILE 40.A O no hydrogen 2.754 N/A ASN 45.A N GLN 41.A O no hydrogen 3.342 N/A ASN 45.A ND2 THR 6.A O no hydrogen 2.976 N/A ILE 47.A N LEU 43.A O no hydrogen 2.721 N/A ILE 48.A N ASN 45.A O no hydrogen 3.037 N/A GLY 54.A N LYS 85.A O no hydrogen 3.409 N/A VAL 55.A N ARG 110.A O no hydrogen 3.232 N/A PHE 56.A N PHE 87.A O no hydrogen 2.629 N/A VAL 57.A N SER 112.A O no hydrogen 3.006 N/A THR 58.A OG1 GLU 61.A O no hydrogen 2.608 N/A ASP 65.A N THR 62.A OG1 no hydrogen 3.068 N/A ILE 66.A N THR 62.A O no hydrogen 3.257 N/A LYS 68.A N GLN 64.A O no hydrogen 2.574 N/A ALA 70.A N ILE 66.A O no hydrogen 3.054 N/A SER 72.A N ASN 69.A O no hydrogen 3.300 N/A PHE 73.A N ALA 70.A O no hydrogen 3.511 N/A VAL 81.A N LEU 77.A O no hydrogen 2.952 N/A LYS 85.A N LEU 80.A O no hydrogen 3.022 N/A LEU 86.A N LEU 80.A O no hydrogen 3.096 N/A PHE 87.A N GLY 54.A O no hydrogen 3.247 N/A LEU 89.A N PHE 56.A O no hydrogen 2.658 N/A ARG 98.A N ALA 94.A O no hydrogen 3.451 N/A ILE 99.A N LEU 95.A O no hydrogen 3.130 N/A ASN 100.A N ILE 96.A O no hydrogen 2.689 N/A TYR 101.A N GLU 97.A O no hydrogen 2.697 N/A ALA 102.A N ARG 98.A O no hydrogen 2.613 N/A ILE 103.A N ILE 99.A O no hydrogen 3.036 N/A LYS 105.A N TYR 101.A O no hydrogen 3.035 N/A VAL 111.A N THR 146.A O no hydrogen 3.191 N/A SER 112.A N VAL 55.A O no hydrogen 3.288 N/A SER 112.A OG SER 39.A O no hydrogen 3.199 N/A ILE 113.A N VAL 148.A O no hydrogen 2.891 N/A ASP 114.A N VAL 57.A O no hydrogen 3.252 N/A VAL 116.A N THR 150.A O no hydrogen 3.467 N/A SER 118.A OG SER 115.A O no hydrogen 2.463 N/A TYR 123.A N PHE 120.A O no hydrogen 3.143 N/A ASP 124.A N PHE 120.A O no hydrogen 3.053 N/A ALA 125.A N ASP 124.A OD2 no hydrogen 2.777 N/A VAL 128.A N ALA 125.A O no hydrogen 3.262 N/A ARG 131.A N SER 127.A O no hydrogen 3.308 N/A GLU 132.A N VAL 128.A O no hydrogen 3.017 N/A LEU 133.A N VAL 129.A O no hydrogen 2.631 N/A PHE 134.A N ARG 130.A O no hydrogen 2.787 N/A VAL 137.A N LEU 133.A O no hydrogen 3.006 N/A ALA 138.A N PHE 134.A O no hydrogen 2.859 N/A ARG 139.A N ARG 135.A O no hydrogen 2.897 N/A LEU 140.A N LEU 136.A O no hydrogen 3.038 N/A LEU 140.A N VAL 137.A O no hydrogen 2.995 N/A LYS 141.A N VAL 137.A O no hydrogen 2.930 N/A GLN 142.A N ALA 138.A O no hydrogen 3.072 N/A ILE 143.A N LEU 140.A O no hydrogen 3.131 N/A GLY 144.A N LYS 141.A O no hydrogen 3.374 N/A VAL 148.A N VAL 111.A O no hydrogen 2.885 N/A MET 149.A N THR 25.A O no hydrogen 2.697 N/A THR 150.A N ILE 113.A O no hydrogen 2.943 N/A THR 150.A OG1 ASP 114.A OD1 no hydrogen 3.291 N/A THR 151.A N VAL 27.A O no hydrogen 3.146 N/A GLU 152.A N THR 117.A OG1 no hydrogen 3.295 N/A ARG 153.A NE PRO 159.A O no hydrogen 3.176 N/A TYR 157.A OH GLU 203.A OE1 no hydrogen 3.413 N/A ARG 162.A NE GLU 152.A OE1 no hydrogen 3.227 N/A ARG 162.A NH2 GLU 152.A OE1 no hydrogen 3.328 N/A VAL 165.A N GLU 166.A OE2 no hydrogen 2.589 N/A GLU 167.A N GLU 167.A OE1 no hydrogen 2.915 N/A SER 170.A N GLU 166.A O no hydrogen 2.791 N/A SER 170.A OG GLU 166.A O no hydrogen 2.490 N/A ASN 172.A ND2 THR 25.A OG1 no hydrogen 2.552 N/A VAL 173.A N LYS 193.A O no hydrogen 3.356 N/A VAL 174.A N LEU 26.A O no hydrogen 2.911 N/A ILE 175.A N GLU 190.A O no hydrogen 2.963 N/A LEU 176.A N SER 28.A O no hydrogen 2.865 N/A ARG 177.A N THR 188.A O no hydrogen 3.003 N/A ARG 177.A NE GLU 156.A O no hydrogen 3.066 N/A ARG 177.A NH1 GLU 190.A OE1 no hydrogen 3.289 N/A ARG 177.A NH2 GLU 190.A OE1 no hydrogen 3.220 N/A ASN 178.A N GLU 156.A OE2 no hydrogen 3.136 N/A VAL 179.A N ARG 186.A O no hydrogen 3.097 N/A GLU 181.A N ARG 184.A O no hydrogen 2.938 N/A ARG 186.A N VAL 179.A O no hydrogen 2.796 N/A ARG 186.A NH2 GLN 355.A OE1 no hydrogen 2.944 N/A ARG 187.A NH1 GLY 32.A O no hydrogen 2.545 N/A ARG 187.A NH2 GLY 32.A O no hydrogen 3.034 N/A THR 188.A N ARG 177.A O no hydrogen 3.389 N/A THR 188.A OG1 GLU 203.A OE2 no hydrogen 2.883 N/A LEU 189.A N TYR 204.A O no hydrogen 3.252 N/A GLU 190.A N ILE 175.A O no hydrogen 3.208 N/A LEU 192.A N VAL 173.A O no hydrogen 2.791 N/A LYS 193.A NZ GLU 167.A O no hydrogen 3.420 N/A ARG 195.A NH2 PHE 168.A O no hydrogen 2.933 N/A THR 197.A OG1 SER 198.A O no hydrogen 3.387 N/A SER 198.A OG HIS 16.A ND1 no hydrogen 2.651 N/A MET 200.A N ILE 14.A O no hydrogen 2.620 N/A TYR 204.A N LEU 189.A O no hydrogen 2.838 N/A TYR 204.A OH LYS 201.A O no hydrogen 2.941 N/A PHE 206.A N ARG 187.A O no hydrogen 3.000 N/A THR 207.A N ASN 214.A O no hydrogen 3.381 N/A THR 209.A N GLY 212.A O no hydrogen 2.711 N/A THR 209.A OG1 GLY 212.A O no hydrogen 3.375 N/A GLY 212.A N THR 209.A O no hydrogen 2.678 N/A ILE 213.A N GLN 41.A OE1 no hydrogen 2.554 N/A ILE 215.A N GLU 9.A O no hydrogen 3.216 N/A PHE 216.A N PRO 205.A O no hydrogen 3.183 N/A SER 220.A N ASP 242.A OD2 no hydrogen 3.263 N/A SER 220.A OG ASP 242.A OD1 no hydrogen 3.194 N/A SER 220.A OG ASP 242.A OD2 no hydrogen 3.363 N/A ARG 223.A NH1 CYS 235.A O no hydrogen 2.443 N/A ARG 223.A NH1 GLY 238.A O no hydrogen 3.040 N/A ARG 223.A NH2 SER 420.A OG no hydrogen 2.536 N/A VAL 224.A N PHE 239.A O no hydrogen 2.648 N/A SER 225.A OG ASP 232.A OD2 no hydrogen 2.568 N/A SER 226.A N ASP 232.A OD1 no hydrogen 3.358 N/A SER 226.A OG ASP 232.A OD1 no hydrogen 2.722 N/A GLY 227.A N SER 225.A OG no hydrogen 3.359 N/A ARG 230.A NH2 GLU 233.A OE1 no hydrogen 2.859 N/A ASP 232.A N VAL 228.A O no hydrogen 3.317 N/A GLU 233.A N VAL 229.A O no hydrogen 2.831 N/A MET 234.A N ARG 230.A O no hydrogen 2.686 N/A CYS 235.A N LEU 231.A O no hydrogen 2.940 N/A CYS 235.A SG LEU 231.A O no hydrogen 3.224 N/A GLY 236.A N GLU 233.A O no hydrogen 3.333 N/A GLY 237.A N ASP 232.A O no hydrogen 2.729 N/A GLY 238.A N ASP 232.A O no hydrogen 2.948 N/A LYS 241.A N VAL 222.A O no hydrogen 2.542 N/A ASP 242.A N ASP 242.A OD1 no hydrogen 2.543 N/A SER 243.A OG PHE 240.A O no hydrogen 2.890 N/A ILE 244.A N ASP 394.A OD2 no hydrogen 3.051 N/A ILE 245.A N GLY 371.A O no hydrogen 3.122 N/A LEU 246.A N THR 395.A O no hydrogen 3.006 N/A ALA 247.A N PHE 373.A O no hydrogen 3.046 N/A THR 248.A OG1 ASN 375.A O no hydrogen 3.424 N/A GLY 249.A N ASN 375.A O no hydrogen 3.175 N/A THR 253.A OG1 ALA 250.A O no hydrogen 2.414 N/A LYS 255.A NZ GLY 249.A O no hydrogen 2.872 N/A LYS 255.A NZ ALA 250.A O no hydrogen 2.482 N/A LYS 255.A NZ THR 253.A OG1 no hydrogen 3.259 N/A LYS 255.A NZ THR 376.A OG1 no hydrogen 3.186 N/A THR 256.A OG1 ASP 339.A OD2 no hydrogen 2.678 N/A LEU 258.A N GLY 254.A O no hydrogen 3.284 N/A VAL 259.A N LYS 255.A O no hydrogen 3.039 N/A SER 260.A N THR 256.A O no hydrogen 2.938 N/A SER 260.A OG THR 256.A O no hydrogen 2.690 N/A ARG 261.A N LEU 257.A O no hydrogen 3.087 N/A ARG 261.A NH1 LYS 434.A O no hydrogen 2.783 N/A PHE 262.A N LEU 258.A O no hydrogen 2.876 N/A VAL 263.A N VAL 259.A O no hydrogen 2.860 N/A GLU 264.A N SER 260.A O no hydrogen 2.846 N/A ASN 265.A N ARG 261.A O no hydrogen 3.246 N/A CYS 267.A N VAL 263.A O no hydrogen 3.366 N/A CYS 267.A SG VAL 263.A O no hydrogen 3.507 N/A ALA 268.A N GLU 264.A O no hydrogen 2.818 N/A ASN 269.A N ASN 265.A O no hydrogen 3.291 N/A ASN 269.A N ALA 266.A O no hydrogen 3.089 N/A LYS 270.A N CYS 267.A O no hydrogen 3.227 N/A GLU 271.A N ALA 266.A O no hydrogen 2.791 N/A ARG 272.A NE LYS 332.A O no hydrogen 3.094 N/A ARG 272.A NH2 LYS 332.A O no hydrogen 3.072 N/A ALA 273.A N LEU 304.A O no hydrogen 2.796 N/A ILE 274.A N ARG 335.A O no hydrogen 3.273 N/A LEU 275.A N LYS 306.A O no hydrogen 2.943 N/A PHE 276.A N ALA 337.A O no hydrogen 2.865 N/A TYR 278.A N ASP 339.A O no hydrogen 2.752 N/A LEU 285.A N SER 281.A O no hydrogen 2.991 N/A LEU 286.A N ARG 282.A O no hydrogen 2.905 N/A ARG 287.A N ALA 283.A O no hydrogen 3.407 N/A ASN 288.A N GLN 284.A O no hydrogen 2.824 N/A ALA 289.A N LEU 285.A O no hydrogen 2.705 N/A TYR 290.A N LEU 286.A O no hydrogen 2.850 N/A SER 291.A N ARG 287.A O no hydrogen 2.938 N/A SER 291.A OG ARG 287.A O no hydrogen 3.181 N/A TRP 292.A N ALA 289.A O no hydrogen 3.062 N/A GLY 293.A N TYR 290.A O no hydrogen 2.979 N/A MET 294.A N ALA 289.A O no hydrogen 3.127 N/A GLU 298.A N ASP 295.A OD1 no hydrogen 3.261 N/A MET 299.A N ASP 295.A O no hydrogen 3.078 N/A GLU 300.A N PHE 296.A O no hydrogen 3.325 N/A ARG 301.A N GLU 297.A O no hydrogen 3.324 N/A ARG 301.A N GLU 298.A O no hydrogen 2.829 N/A ASN 303.A N GLU 300.A O no hydrogen 3.170 N/A LEU 305.A N MET 299.A O no hydrogen 3.250 N/A LYS 306.A N ALA 273.A O no hydrogen 3.152 N/A VAL 308.A N LEU 275.A O no hydrogen 3.116 N/A ALA 310.A N ALA 277.A O no hydrogen 3.222 N/A SER 314.A N TYR 311.A O no hydrogen 3.275 N/A SER 314.A OG TYR 311.A O no hydrogen 3.063 N/A GLY 316.A N ASP 319.A OD2 no hydrogen 3.270 N/A ASP 319.A N GLY 316.A O no hydrogen 2.929 N/A HIS 320.A N GLY 316.A O no hydrogen 2.810 N/A ILE 323.A N ASP 319.A O no hydrogen 3.360 N/A ILE 324.A N HIS 320.A O no hydrogen 3.147 N/A LYS 325.A N LEU 321.A O no hydrogen 2.889 N/A SER 326.A N GLN 322.A O no hydrogen 2.834 N/A SER 326.A OG GLN 322.A OE1 no hydrogen 3.388 N/A GLU 327.A N ILE 323.A O no hydrogen 2.787 N/A ILE 328.A N ILE 324.A O no hydrogen 2.900 N/A ILE 328.A N LYS 325.A O no hydrogen 2.932 N/A ASN 329.A N LYS 325.A O no hydrogen 2.783 N/A ASP 330.A N SER 326.A O no hydrogen 3.189 N/A PHE 331.A N GLU 327.A O no hydrogen 3.423 N/A ALA 334.A N ARG 272.A O no hydrogen 2.750 N/A ARG 335.A N ARG 272.A O no hydrogen 3.410 N/A ARG 335.A NH1 SER 225.A O no hydrogen 2.796 N/A ARG 335.A NH1 PHE 262.A O no hydrogen 2.791 N/A ARG 335.A NH2 SER 225.A O no hydrogen 3.264 N/A ILE 336.A N THR 370.A O no hydrogen 2.767 N/A ALA 337.A N ILE 274.A O no hydrogen 2.935 N/A ILE 338.A N LEU 372.A O no hydrogen 3.241 N/A ASP 339.A N PHE 276.A O no hydrogen 2.776 N/A SER 340.A OG GLU 279.A OE2 no hydrogen 2.460 N/A SER 340.A OG SER 342.A OG no hydrogen 2.585 N/A LEU 341.A N THR 374.A O no hydrogen 3.246 N/A SER 342.A OG GLU 279.A OE2 no hydrogen 3.454 N/A SER 342.A OG SER 340.A OG no hydrogen 2.585 N/A LEU 344.A N LEU 341.A O no hydrogen 2.764 N/A ALA 345.A N SER 342.A O no hydrogen 3.397 N/A ARG 346.A NH1 GLU 313.A OE1 no hydrogen 3.048 N/A PHE 353.A N SER 349.A O no hydrogen 2.783 N/A ARG 354.A N ASN 350.A O no hydrogen 3.162 N/A ARG 354.A NH1 ASN 351.A OD1 no hydrogen 2.960 N/A ARG 354.A NH2 ASN 351.A OD1 no hydrogen 2.812 N/A GLN 355.A N ASN 351.A O no hydrogen 3.027 N/A VAL 357.A N PHE 353.A O no hydrogen 3.184 N/A ILE 358.A N ARG 354.A O no hydrogen 3.119 N/A GLY 359.A N GLN 355.A O no hydrogen 3.173 N/A VAL 360.A N PHE 356.A O no hydrogen 2.985 N/A THR 361.A N VAL 357.A O no hydrogen 2.980 N/A THR 361.A OG1 VAL 357.A O no hydrogen 2.456 N/A GLY 362.A N ILE 358.A O no hydrogen 2.887 N/A TYR 363.A N GLY 359.A O no hydrogen 2.920 N/A ALA 364.A N VAL 360.A O no hydrogen 2.604 N/A LYS 365.A N THR 361.A O no hydrogen 2.793 N/A GLN 366.A N GLY 362.A O no hydrogen 2.566 N/A GLU 367.A N TYR 363.A O no hydrogen 3.012 N/A GLU 368.A N LYS 365.A O no hydrogen 3.199 N/A ILE 369.A N ALA 364.A O no hydrogen 2.645 N/A THR 370.A OG1 LYS 241.A O no hydrogen 2.465 N/A LEU 372.A N ILE 336.A O no hydrogen 3.173 N/A PHE 373.A N ILE 245.A O no hydrogen 3.023 N/A THR 374.A N ILE 338.A O no hydrogen 3.091 N/A THR 374.A OG1 ASP 339.A OD1 no hydrogen 2.544 N/A ASN 375.A N ALA 247.A O no hydrogen 2.942 N/A ASN 375.A ND2 THR 248.A OG1 no hydrogen 2.706 N/A SER 377.A N GLY 249.A O no hydrogen 2.893 N/A SER 377.A OG GLN 379.A O no hydrogen 3.184 N/A ILE 392.A N ILE 389.A O no hydrogen 3.478 N/A THR 393.A OG1 THR 395.A O no hydrogen 2.499 N/A ASP 394.A N ILE 244.A O no hydrogen 2.965 N/A THR 395.A N ILE 244.A O no hydrogen 3.273 N/A ILE 396.A N LYS 416.A O no hydrogen 3.305 N/A ILE 397.A N LEU 246.A O no hydrogen 2.694 N/A LEU 399.A N THR 248.A O no hydrogen 2.840 N/A GLN 400.A N ALA 411.A O no hydrogen 2.969 N/A GLN 400.A NE2 PHE 380.A O no hydrogen 3.516 N/A GLN 400.A NE2 TYR 401.A O no hydrogen 2.993 N/A TYR 401.A OH THR 251.A O no hydrogen 2.555 N/A VAL 402.A N SER 409.A O no hydrogen 2.605 N/A ILE 404.A N GLU 407.A O no hydrogen 2.907 N/A SER 409.A N VAL 402.A O no hydrogen 2.962 N/A SER 409.A N GLU 407.A O no hydrogen 2.935 N/A SER 409.A OG VAL 402.A O no hydrogen 2.512 N/A ARG 410.A NH1 GLY 252.A O no hydrogen 2.652 N/A ARG 410.A NH1 THR 253.A O no hydrogen 2.706 N/A ARG 410.A NH2 GLY 252.A O no hydrogen 3.244 N/A ALA 411.A N GLN 400.A O no hydrogen 2.881 N/A ILE 412.A N ARG 427.A O no hydrogen 2.885 N/A ASN 413.A N LEU 398.A O no hydrogen 3.403 N/A PHE 415.A N ILE 396.A O no hydrogen 2.834 N/A LYS 416.A NZ CYS 390.A O no hydrogen 2.795 N/A LYS 416.A NZ THR 393.A O no hydrogen 2.550 N/A ARG 418.A N ASP 394.A O no hydrogen 2.818 N/A ARG 418.A NH1 ASP 394.A OD1 no hydrogen 3.206 N/A ARG 418.A NH2 VAL 391.A O no hydrogen 2.262 N/A SER 420.A OG TRP 421.A O no hydrogen 2.984 N/A HIS 422.A ND1 VAL 414.A O no hydrogen 2.894 N/A ASP 423.A N MET 234.A O no hydrogen 2.612 N/A ARG 427.A NE ASP 423.A OD2 no hydrogen 2.773 N/A GLU 428.A N ASP 440.A O no hydrogen 3.269 N/A PHE 429.A N ARG 410.A O no hydrogen 3.342 N/A SER 432.A N GLY 435.A O no hydrogen 3.234 N/A LYS 434.A N SER 432.A OG no hydrogen 3.209 N/A ASP 437.A N MET 430.A O no hydrogen 3.090 N/A LYS 439.A N GLU 428.A O no hydrogen 2.855 N/A GLU 446.A N THR 454.A O no hydrogen 2.749 N/A SER 450.A OG ARG 447.A O no hydrogen 2.945 N/A SER 450.A OG SER 452.A O no hydrogen 3.536 N/A SER 452.A N SER 450.A O no hydrogen 2.743 N/A ILE 456.A N ASN 444.A O no hydrogen 3.246 N/A