Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8xfl_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): VAL 3.A N TYR 6.A O no hydrogen 2.956 N/A TYR 6.A N VAL 3.A O no hydrogen 2.767 N/A TYR 6.A OH GLU 70.A OE2 no hydrogen 2.740 N/A ARG 7.A N ARG 24.A O no hydrogen 2.980 N/A LEU 8.A N PRO 1.A O no hydrogen 2.776 N/A LEU 9.A N LEU 22.A O no hydrogen 2.914 N/A ILE 12.A N VAL 20.A O no hydrogen 2.916 N/A LYS 19.A N ILE 36.A O no hydrogen 3.076 N/A VAL 20.A N GLY 13.A O no hydrogen 3.383 N/A LYS 21.A N ILE 34.A O no hydrogen 2.941 N/A LEU 22.A N ARG 10.A O no hydrogen 2.878 N/A ALA 23.A N VAL 32.A O no hydrogen 2.934 N/A ARG 24.A N ARG 7.A O no hydrogen 2.813 N/A ARG 24.A NE GLY 29.A O no hydrogen 3.390 N/A HIS 25.A N ARG 30.A O no hydrogen 2.860 N/A HIS 25.A ND1 THR 28.A OG1 no hydrogen 2.480 N/A ILE 26.A N ASN 5.A O no hydrogen 2.755 N/A THR 28.A OG1 HIS 25.A ND1 no hydrogen 2.480 N/A GLY 29.A N HIS 25.A O no hydrogen 2.675 N/A ARG 30.A N THR 28.A OG1 no hydrogen 3.321 N/A ARG 30.A NH1 LYS 299.A OXT no hydrogen 2.966 N/A VAL 32.A N ALA 23.A O no hydrogen 3.144 N/A ALA 33.A N MET 82.A O no hydrogen 3.032 N/A ILE 34.A N LYS 21.A O no hydrogen 2.867 N/A LYS 35.A N LEU 80.A O no hydrogen 2.838 N/A ILE 36.A N LYS 19.A O no hydrogen 2.772 N/A ILE 37.A N LEU 78.A O no hydrogen 3.043 N/A LYS 39.A N LYS 76.A O no hydrogen 2.710 N/A LYS 39.A NZ GLU 73.A OE2 no hydrogen 2.691 N/A LYS 39.A NZ THR 74.A O no hydrogen 2.939 N/A GLN 41.A NE2 ASP 38.A OD2 no hydrogen 3.501 N/A SER 45.A N ASN 43.A OD1 no hydrogen 2.886 N/A SER 46.A N ASN 43.A O no hydrogen 2.699 N/A SER 46.A OG ASN 43.A O no hydrogen 2.371 N/A LEU 47.A N ASN 43.A O no hydrogen 3.401 N/A LYS 49.A N SER 46.A O no hydrogen 2.780 N/A LYS 49.A NZ SER 150.A OG no hydrogen 3.077 N/A LEU 50.A N SER 46.A O no hydrogen 2.651 N/A PHE 51.A N LEU 47.A O no hydrogen 2.919 N/A GLU 53.A N LYS 49.A O no hydrogen 2.930 N/A VAL 54.A N LEU 50.A O no hydrogen 2.885 N/A ARG 55.A N PHE 51.A O no hydrogen 2.814 N/A ARG 55.A N ARG 52.A O no hydrogen 3.256 N/A ILE 56.A N ARG 52.A O no hydrogen 3.356 N/A MET 57.A N GLU 53.A O no hydrogen 2.898 N/A LYS 58.A N VAL 54.A O no hydrogen 3.268 N/A LYS 58.A N ARG 55.A O no hydrogen 3.211 N/A GLY 59.A N ILE 56.A O no hydrogen 2.806 N/A LEU 60.A N ILE 56.A O no hydrogen 3.189 N/A ASN 61.A N TYR 118.A OH no hydrogen 2.692 N/A HIS 62.A NE2 SER 114.A OG no hydrogen 3.389 N/A ASN 64.A N HIS 62.A ND1 no hydrogen 2.835 N/A ASN 64.A ND2 ILE 142.A O no hydrogen 3.105 N/A ILE 65.A N HIS 62.A O no hydrogen 3.264 N/A VAL 66.A N ILE 144.A O no hydrogen 2.960 N/A LYS 67.A N GLU 83.A OE2 no hydrogen 2.969 N/A LYS 67.A NZ ASN 61.A OD1 no hydrogen 3.100 N/A PHE 69.A N VAL 81.A O no hydrogen 2.676 N/A GLU 70.A N VAL 81.A O no hydrogen 3.487 N/A VAL 71.A N TYR 286.A O no hydrogen 2.960 N/A ILE 72.A N TYR 79.A O no hydrogen 2.933 N/A THR 74.A N THR 77.A O no hydrogen 2.896 N/A THR 74.A OG1 THR 77.A O no hydrogen 3.151 N/A THR 74.A OG1 THR 77.A OG1 no hydrogen 2.599 N/A THR 77.A N THR 74.A O no hydrogen 3.250 N/A THR 77.A N THR 74.A OG1 no hydrogen 3.019 N/A THR 77.A OG1 THR 74.A OG1 no hydrogen 2.599 N/A LEU 78.A N ILE 37.A O no hydrogen 2.946 N/A TYR 79.A N ILE 72.A O no hydrogen 2.714 N/A LEU 80.A N LYS 35.A O no hydrogen 2.852 N/A VAL 81.A N GLU 70.A O no hydrogen 2.973 N/A MET 82.A N ALA 33.A O no hydrogen 2.720 N/A GLU 83.A N LYS 67.A O no hydrogen 3.196 N/A ALA 87.A N LEU 136.A O no hydrogen 3.041 N/A GLY 88.A N ALA 85.A O no hydrogen 3.019 N/A VAL 90.A N LEU 134.A O no hydrogen 3.207 N/A TYR 93.A N VAL 90.A O no hydrogen 3.021 N/A LEU 94.A N PHE 91.A O no hydrogen 3.251 N/A VAL 95.A N PHE 91.A O no hydrogen 3.023 N/A SER 96.A OG ASP 92.A O no hydrogen 2.772 N/A HIS 97.A N TYR 93.A O no hydrogen 2.841 N/A ARG 99.A NH1 VAL 179.A O no hydrogen 3.430 N/A MET 100.A N LEU 178.A O no hydrogen 3.077 N/A ALA 105.A N LYS 101.A O no hydrogen 2.836 N/A ARG 106.A N GLU 102.A O no hydrogen 2.896 N/A ARG 106.A NE TRP 238.A O no hydrogen 2.582 N/A ALA 107.A N LYS 103.A O no hydrogen 3.060 N/A LYS 108.A N GLU 104.A O no hydrogen 3.088 N/A LYS 108.A NZ ALA 140.A O no hydrogen 2.494 N/A PHE 109.A N ALA 105.A O no hydrogen 2.807 N/A ARG 110.A N ARG 106.A O no hydrogen 2.930 N/A ARG 110.A NH1 ILE 239.A O no hydrogen 2.792 N/A ARG 110.A NH1 ASN 240.A OD1 no hydrogen 2.680 N/A ARG 110.A NH2 GLU 246.A O no hydrogen 2.784 N/A GLN 111.A N ALA 107.A O no hydrogen 3.438 N/A GLN 111.A NE2 ASN 141.A OD1 no hydrogen 2.826 N/A ILE 112.A N LYS 108.A O no hydrogen 3.187 N/A VAL 113.A N PHE 109.A O no hydrogen 3.045 N/A SER 114.A N ARG 110.A O no hydrogen 2.737 N/A SER 114.A OG HIS 62.A NE2 no hydrogen 3.389 N/A ALA 115.A N GLN 111.A O no hydrogen 3.090 N/A VAL 116.A N ILE 112.A O no hydrogen 2.908 N/A HIS 117.A N VAL 113.A O no hydrogen 2.998 N/A TYR 118.A N SER 114.A O no hydrogen 3.027 N/A TYR 118.A OH GLY 59.A O no hydrogen 3.129 N/A TYR 118.A OH GLU 253.A OE2 no hydrogen 2.512 N/A CYS 119.A N ALA 115.A O no hydrogen 3.073 N/A CYS 119.A SG ALA 115.A O no hydrogen 3.347 N/A HIS 120.A N VAL 116.A O no hydrogen 2.855 N/A HIS 120.A ND1 ILE 124.A O no hydrogen 2.992 N/A GLN 121.A N HIS 117.A O no hydrogen 2.724 N/A LYS 122.A N TYR 118.A O no hydrogen 3.152 N/A LYS 122.A N CYS 119.A O no hydrogen 3.294 N/A LYS 122.A NZ GLY 59.A O no hydrogen 2.772 N/A LYS 122.A NZ TYR 118.A OH no hydrogen 3.426 N/A LYS 122.A NZ GLU 253.A OE2 no hydrogen 2.816 N/A ASN 123.A N HIS 120.A O no hydrogen 2.776 N/A ILE 124.A N CYS 119.A O no hydrogen 2.695 N/A HIS 126.A N ASP 167.A OD2 no hydrogen 3.203 N/A HIS 126.A NE2 ALA 145.A O no hydrogen 3.106 N/A ARG 127.A N ASP 167.A OD1 no hydrogen 2.931 N/A ASP 128.A N HIS 126.A ND1 no hydrogen 3.207 N/A LYS 130.A N ASN 133.A OD1 no hydrogen 2.881 N/A LYS 130.A NZ ASP 128.A OD1 no hydrogen 3.305 N/A LYS 130.A NZ ASP 128.A OD2 no hydrogen 3.054 N/A ASN 133.A N LYS 130.A O no hydrogen 3.349 N/A ASN 133.A ND2 ASP 128.A O no hydrogen 2.854 N/A LEU 134.A N LYS 130.A O no hydrogen 3.391 N/A LEU 135.A N LYS 143.A O no hydrogen 3.010 N/A LEU 136.A N GLY 88.A O no hydrogen 2.846 N/A ASP 137.A N ASN 141.A O no hydrogen 2.855 N/A ALA 140.A N ASP 137.A O no hydrogen 2.998 N/A ASN 141.A N ASP 137.A OD1 no hydrogen 2.818 N/A ILE 142.A N GLN 111.A OE1 no hydrogen 2.939 N/A LYS 143.A N LEU 135.A O no hydrogen 2.756 N/A LYS 143.A NZ PRO 63.A O no hydrogen 2.905 N/A LYS 143.A NZ GLU 83.A OE1 no hydrogen 2.882 N/A ILE 144.A N ASN 64.A O no hydrogen 2.996 N/A ALA 145.A N ASN 133.A O no hydrogen 2.976 N/A PHE 149.A N ASP 146.A O no hydrogen 3.386 N/A SER 150.A OG GLU 53.A OE2 no hydrogen 2.712 N/A GLU 152.A N ASN 151.A OD1 no hydrogen 2.452 N/A GLU 165.A N GLU 165.A OE1 no hydrogen 2.807 N/A VAL 166.A N GLY 163.A O no hydrogen 3.157 N/A ASP 167.A N PRO 164.A O no hydrogen 3.182 N/A ILE 168.A N PRO 164.A O no hydrogen 3.151 N/A TRP 169.A N GLU 165.A O no hydrogen 3.333 N/A SER 170.A OG TYR 157.A O no hydrogen 2.591 N/A SER 170.A OG VAL 166.A O no hydrogen 2.909 N/A LEU 171.A N ASP 167.A O no hydrogen 2.709 N/A GLY 172.A N ILE 168.A O no hydrogen 3.061 N/A VAL 173.A N TRP 169.A O no hydrogen 3.097 N/A ILE 174.A N SER 170.A O no hydrogen 3.031 N/A LEU 175.A N LEU 171.A O no hydrogen 2.819 N/A TYR 176.A N GLY 172.A O no hydrogen 3.079 N/A TYR 176.A OH ARG 203.A O no hydrogen 2.505 N/A THR 177.A N VAL 173.A O no hydrogen 2.976 N/A THR 177.A OG1 VAL 173.A O no hydrogen 3.323 N/A THR 177.A OG1 ILE 174.A O no hydrogen 2.415 N/A LEU 178.A N ILE 174.A O no hydrogen 2.848 N/A VAL 179.A N LEU 175.A O no hydrogen 3.106 N/A SER 180.A N TYR 176.A O no hydrogen 2.783 N/A SER 180.A OG TYR 176.A O no hydrogen 2.799 N/A GLY 181.A N THR 177.A O no hydrogen 2.718 N/A SER 182.A N SER 180.A OG no hydrogen 3.039 N/A GLY 187.A N ASP 186.A OD1 no hydrogen 2.877 N/A HIS 188.A N GLU 192.A OE1 no hydrogen 2.894 N/A ARG 196.A N GLU 192.A O no hydrogen 3.442 N/A ARG 196.A NH2 GLU 192.A OE2 no hydrogen 2.787 N/A VAL 197.A N LEU 193.A O no hydrogen 3.226 N/A LEU 198.A N ARG 194.A O no hydrogen 2.769 N/A ARG 199.A N GLU 195.A O no hydrogen 3.250 N/A ARG 199.A NH1 GLU 195.A OE1 no hydrogen 3.117 N/A ARG 199.A NH2 GLU 195.A OE1 no hydrogen 3.555 N/A GLY 200.A N ARG 196.A O no hydrogen 2.955 N/A TYR 207.A OH SER 180.A O no hydrogen 2.918 N/A MET 208.A N PRO 205.A O no hydrogen 3.182 N/A SER 209.A N GLU 102.A OE2 no hydrogen 2.765 N/A SER 209.A OG GLU 102.A OE1 no hydrogen 2.569 N/A SER 209.A OG GLU 102.A OE2 no hydrogen 2.864 N/A CYS 212.A N SER 209.A OG no hydrogen 3.004 N/A GLU 213.A N SER 209.A O no hydrogen 2.970 N/A SER 214.A N THR 210.A O no hydrogen 2.903 N/A SER 214.A OG THR 210.A O no hydrogen 2.491 N/A ILE 215.A N ASP 211.A O no hydrogen 3.033 N/A LEU 216.A N CYS 212.A O no hydrogen 2.965 N/A ARG 217.A N GLU 213.A O no hydrogen 3.189 N/A ARG 217.A N SER 214.A O no hydrogen 3.207 N/A ARG 218.A NH2 ASP 236.A OD2 no hydrogen 3.195 N/A PHE 219.A N ILE 215.A O no hydrogen 3.427 N/A LEU 220.A N LEU 216.A O no hydrogen 3.087 N/A LYS 226.A N ASN 223.A O no hydrogen 3.034 N/A ARG 227.A N PRO 224.A O no hydrogen 3.157 N/A ARG 227.A NH1 GLU 161.A OE1 no hydrogen 3.320 N/A ARG 227.A NH1 GLU 161.A OE2 no hydrogen 3.101 N/A ARG 227.A NH2 GLU 161.A OE2 no hydrogen 3.441 N/A ARG 227.A NH2 VAL 221.A O no hydrogen 2.977 N/A CYS 228.A N ARG 218.A O no hydrogen 3.459 N/A THR 229.A N GLN 232.A OE1 no hydrogen 3.132 N/A THR 229.A OG1 GLU 231.A OE2 no hydrogen 3.336 N/A GLU 231.A N GLU 231.A OE2 no hydrogen 2.669 N/A GLN 232.A N THR 229.A OG1 no hydrogen 3.302 N/A ILE 233.A N THR 229.A O no hydrogen 2.827 N/A MET 234.A N LEU 230.A O no hydrogen 3.050 N/A LYS 235.A N GLN 232.A O no hydrogen 2.648 N/A ASP 236.A N ILE 233.A O no hydrogen 3.272 N/A LYS 237.A NZ ASP 211.A OD1 no hydrogen 2.907 N/A LYS 237.A NZ ASP 211.A OD2 no hydrogen 3.486 N/A TRP 238.A N ASP 236.A OD1 no hydrogen 2.760 N/A TRP 238.A NE1 GLU 102.A OE1 no hydrogen 3.194 N/A ASN 240.A N LYS 237.A O no hydrogen 3.106 N/A ASN 240.A ND2 MET 234.A O no hydrogen 2.873 N/A ASN 240.A ND2 ASP 236.A O no hydrogen 3.269 N/A ILE 241.A N TRP 238.A O no hydrogen 3.205 N/A TYR 243.A N ASN 240.A O no hydrogen 3.331 N/A GLU 244.A N GLU 244.A OE1 no hydrogen 2.796 N/A LEU 248.A N ASN 240.A OD1 no hydrogen 2.980 N/A ASP 260.A N TYR 293.A OH no hydrogen 2.898 N/A ARG 263.A NE ASP 260.A OD2 no hydrogen 2.924 N/A ARG 263.A NH1 TYR 293.A O no hydrogen 2.932 N/A ILE 264.A N ASP 260.A O no hydrogen 3.005 N/A GLU 265.A N THR 261.A O no hydrogen 2.745 N/A VAL 266.A N LYS 262.A O no hydrogen 3.343 N/A MET 267.A N ARG 263.A O no hydrogen 2.894 N/A VAL 268.A N ILE 264.A O no hydrogen 2.647 N/A GLY 269.A N GLU 265.A O no hydrogen 2.853 N/A MET 270.A N MET 267.A O no hydrogen 2.994 N/A GLY 271.A N VAL 268.A O no hydrogen 3.084 N/A TYR 272.A N MET 267.A O no hydrogen 3.145 N/A ARG 274.A NH2 GLU 265.A OE2 no hydrogen 2.759 N/A GLU 275.A N GLU 275.A OE1 no hydrogen 2.760 N/A GLU 276.A N THR 273.A OG1 no hydrogen 3.094 N/A ILE 277.A N THR 273.A O no hydrogen 2.960 N/A LYS 278.A N ARG 274.A O no hydrogen 2.914 N/A GLU 279.A N GLU 275.A O no hydrogen 2.766 N/A SER 280.A N GLU 276.A O no hydrogen 2.951 N/A SER 280.A OG GLU 276.A O no hydrogen 2.581 N/A LEU 281.A N ILE 277.A O no hydrogen 3.032 N/A THR 282.A N LYS 278.A O no hydrogen 3.156 N/A THR 282.A OG1 LYS 278.A O no hydrogen 2.763 N/A THR 282.A OG1 GLU 279.A O no hydrogen 2.862 N/A SER 283.A N GLU 279.A O no hydrogen 3.074 N/A SER 283.A OG GLU 279.A O no hydrogen 2.662 N/A SER 283.A OG SER 280.A O no hydrogen 3.429 N/A GLN 284.A N SER 280.A O no hydrogen 3.105 N/A ASN 287.A ND2 SER 280.A OG no hydrogen 3.258 N/A VAL 289.A N ASN 287.A OD1 no hydrogen 2.778 N/A THR 290.A N ASN 287.A OD1 no hydrogen 2.935 N/A THR 290.A OG1 ASN 287.A O no hydrogen 2.662 N/A THR 290.A OG1 ASN 287.A OD1 no hydrogen 3.550 N/A ALA 291.A N ASN 287.A O no hydrogen 3.049 N/A THR 292.A N GLU 288.A O no hydrogen 3.112 N/A THR 292.A OG1 GLU 288.A O no hydrogen 2.605 N/A TYR 293.A N VAL 289.A O no hydrogen 3.019 N/A TYR 293.A OH ASP 257.A O no hydrogen 2.807 N/A LEU 294.A N THR 290.A O no hydrogen 3.084 N/A LEU 295.A N ALA 291.A O no hydrogen 2.916 N/A LEU 296.A N THR 292.A O no hydrogen 3.180 N/A GLY 297.A N LEU 294.A O no hydrogen 3.011 N/A ARG 298.A N LEU 295.A O no hydrogen 3.095 N/A