Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8xxn_3L.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): GLN 1.A N TYR 248.A OH no hydrogen 3.341 N/A ILE 7.A N LEU 3.A O no hydrogen 2.951 N/A ASP 8.A N TRP 4.A O no hydrogen 2.894 N/A GLU 9.A N ASP 5.A O no hydrogen 2.941 N/A PHE 10.A N ILE 6.A O no hydrogen 2.891 N/A ILE 11.A N ILE 7.A O no hydrogen 2.860 N/A TYR 12.A N ASP 8.A O no hydrogen 2.922 N/A GLN 13.A N GLU 9.A O no hydrogen 2.919 N/A PHE 14.A N PHE 10.A O no hydrogen 2.892 N/A GLN 15.A N ILE 11.A O no hydrogen 2.860 N/A SER 16.A N TYR 12.A O no hydrogen 2.913 N/A SER 16.A OG TYR 12.A O no hydrogen 3.201 N/A SER 16.A OG GLN 13.A O no hydrogen 2.637 N/A PHE 17.A N GLN 13.A O no hydrogen 2.935 N/A SER 18.A N PHE 14.A O no hydrogen 2.879 N/A SER 18.A OG PHE 14.A O no hydrogen 2.603 N/A GLN 19.A N GLN 15.A O no hydrogen 2.923 N/A GLN 19.A NE2 GLN 15.A OE1 no hydrogen 3.368 N/A TYR 20.A N SER 16.A O no hydrogen 2.896 N/A ARG 21.A N PHE 17.A O no hydrogen 2.923 N/A CYS 22.A N SER 18.A O no hydrogen 2.894 N/A LYS 23.A N GLN 19.A O no hydrogen 2.914 N/A LYS 23.A NZ GLN 19.A OE1 no hydrogen 2.934 N/A THR 24.A N TYR 20.A O no hydrogen 3.087 N/A ALA 25.A N TYR 20.A O no hydrogen 2.552 N/A LYS 26.A N THR 24.A O no hydrogen 2.967 N/A LYS 26.A NZ LEU 89.A O no hydrogen 3.341 N/A ASP 33.A N GLU 29.A O no hydrogen 2.920 N/A PHE 34.A N GLU 30.A O no hydrogen 2.904 N/A LEU 35.A N GLU 31.A O no hydrogen 2.939 N/A ARG 36.A N ILE 32.A O no hydrogen 2.918 N/A SER 37.A N ASP 33.A O no hydrogen 2.884 N/A SER 37.A OG ASP 33.A O no hydrogen 2.423 N/A ASN 38.A N PHE 34.A O no hydrogen 2.926 N/A SER 46.A N ASN 43.A O no hydrogen 3.455 N/A VAL 47.A N ASN 43.A O no hydrogen 3.175 N/A VAL 50.A N SER 46.A O no hydrogen 2.966 N/A LEU 51.A N VAL 47.A O no hydrogen 2.919 N/A HIS 52.A N LEU 48.A O no hydrogen 2.854 N/A HIS 52.A ND1 LEU 48.A O no hydrogen 2.382 N/A SER 53.A N ASN 49.A O no hydrogen 2.899 N/A SER 53.A OG ASN 49.A O no hydrogen 2.924 N/A LEU 54.A N VAL 50.A O no hydrogen 2.976 N/A VAL 55.A N LEU 51.A O no hydrogen 2.946 N/A ASP 56.A N HIS 52.A O no hydrogen 2.813 N/A LYS 57.A N SER 53.A O no hydrogen 2.910 N/A SER 58.A N LEU 54.A O no hydrogen 3.014 N/A SER 58.A OG VAL 55.A O no hydrogen 2.737 N/A ASN 59.A N VAL 55.A O no hydrogen 2.896 N/A ASN 59.A ND2 VAL 55.A O no hydrogen 2.824 N/A ILE 60.A N ASP 56.A O no hydrogen 2.769 N/A ASN 61.A N LYS 57.A O no hydrogen 3.016 N/A ASN 61.A ND2 LYS 57.A O no hydrogen 3.169 N/A ARG 62.A N SER 58.A O no hydrogen 2.942 N/A GLN 63.A N ASN 59.A O no hydrogen 2.801 N/A LEU 64.A N ILE 60.A O no hydrogen 2.890 N/A GLU 65.A N ASN 61.A O no hydrogen 2.950 N/A VAL 66.A N ARG 62.A O no hydrogen 2.922 N/A THR 68.A OG1 TYR 255.A OH no hydrogen 2.392 N/A SER 75.A N GLY 71.A O no hydrogen 2.866 N/A SER 75.A OG GLY 71.A O no hydrogen 2.804 N/A SER 75.A OG ASP 72.A O no hydrogen 2.572 N/A VAL 76.A N ASP 72.A O no hydrogen 2.946 N/A ALA 77.A N PRO 73.A O no hydrogen 2.967 N/A GLY 78.A N GLU 74.A O no hydrogen 2.909 N/A GLU 79.A N SER 75.A O no hydrogen 2.923 N/A TYR 80.A N VAL 76.A O no hydrogen 2.956 N/A TYR 80.A N ALA 77.A O no hydrogen 3.379 N/A GLY 81.A N ALA 77.A O no hydrogen 2.933 N/A SER 84.A N TYR 80.A O no hydrogen 2.934 N/A SER 84.A OG TYR 80.A O no hydrogen 2.245 N/A LYS 87.A NZ TYR 86.A OH no hydrogen 3.087 N/A VAL 95.A N SER 93.A OG no hydrogen 3.318 N/A LEU 98.A N LEU 94.A O no hydrogen 2.944 N/A ARG 99.A N VAL 95.A O no hydrogen 2.845 N/A ARG 99.A NH2 SER 53.A OG no hydrogen 3.305 N/A LEU 100.A N GLY 96.A O no hydrogen 2.915 N/A HIS 101.A N LEU 97.A O no hydrogen 2.911 N/A SER 102.A N LEU 98.A O no hydrogen 2.871 N/A SER 102.A OG LEU 98.A O no hydrogen 3.325 N/A LEU 103.A N ARG 99.A O no hydrogen 2.874 N/A LEU 104.A N LEU 100.A O no hydrogen 2.930 N/A GLY 105.A N HIS 101.A O no hydrogen 2.853 N/A ASP 106.A N SER 102.A O no hydrogen 2.920 N/A TYR 107.A N LEU 103.A O no hydrogen 2.834 N/A TYR 108.A N GLY 105.A O no hydrogen 3.313 N/A TYR 108.A OH TYR 138.A O no hydrogen 2.834 N/A GLN 109.A N GLY 105.A O no hydrogen 2.899 N/A ALA 110.A N ASP 106.A O no hydrogen 2.950 N/A LYS 112.A NZ TYR 107.A OH no hydrogen 2.836 N/A ASN 116.A ND2 TYR 143.A OH no hydrogen 2.632 N/A GLU 118.A N GLU 118.A OE1 no hydrogen 2.599 N/A LEU 119.A N GLU 115.A O no hydrogen 2.892 N/A LEU 119.A N ASN 116.A O no hydrogen 3.317 N/A ASN 120.A N ASN 116.A O no hydrogen 2.927 N/A LYS 121.A N ILE 117.A O no hydrogen 2.915 N/A LYS 122.A NZ GLU 118.A O no hydrogen 2.830 N/A SER 123.A OG LYS 122.A O no hydrogen 2.756 N/A GLN 132.A N VAL 128.A O no hydrogen 2.869 N/A VAL 133.A N PRO 129.A O no hydrogen 2.945 N/A THR 134.A N GLU 130.A O no hydrogen 2.958 N/A THR 134.A OG1 GLU 130.A O no hydrogen 2.878 N/A THR 134.A OG1 CYS 131.A O no hydrogen 2.688 N/A THR 135.A N CYS 131.A O no hydrogen 2.938 N/A TYR 136.A N GLN 132.A O no hydrogen 2.888 N/A TYR 137.A N VAL 133.A O no hydrogen 2.930 N/A TYR 138.A N THR 134.A O no hydrogen 2.922 N/A VAL 139.A N THR 135.A O no hydrogen 2.911 N/A GLY 140.A N TYR 136.A O no hydrogen 2.869 N/A PHE 141.A N TYR 137.A O no hydrogen 2.970 N/A ALA 142.A N TYR 138.A O no hydrogen 2.909 N/A TYR 143.A N VAL 139.A O no hydrogen 2.872 N/A LEU 144.A N GLY 140.A O no hydrogen 2.908 N/A MET 145.A N PHE 141.A O no hydrogen 2.934 N/A MET 146.A N ALA 142.A O no hydrogen 2.893 N/A ARG 148.A N TYR 143.A O no hydrogen 3.306 N/A ASP 151.A N ARG 148.A O no hydrogen 3.302 N/A ALA 152.A N ARG 148.A O no hydrogen 2.952 N/A ILE 153.A N TYR 149.A O no hydrogen 2.904 N/A ARG 154.A NH1 GLN 150.A O no hydrogen 2.405 N/A VAL 155.A N ASP 151.A O no hydrogen 2.994 N/A PHE 156.A N ALA 152.A O no hydrogen 2.853 N/A ALA 157.A N ILE 153.A O no hydrogen 2.950 N/A ASN 158.A N ARG 154.A O no hydrogen 2.939 N/A ILE 159.A N VAL 155.A O no hydrogen 2.899 N/A LEU 160.A N PHE 156.A O no hydrogen 2.828 N/A TYR 162.A OH ASP 352.A OD2 no hydrogen 2.863 N/A LYS 167.A NZ ARG 172.A O no hydrogen 3.372 N/A SER 168.A OG THR 173.A OG1 no hydrogen 2.463 N/A ARG 172.A NH1 GLN 171.A O no hydrogen 2.944 N/A THR 173.A OG1 SER 168.A OG no hydrogen 2.463 N/A ASN 181.A N TYR 177.A O no hydrogen 2.917 N/A LYS 182.A N GLU 178.A O no hydrogen 2.900 N/A LYS 182.A NZ GLN 186.A OE1 no hydrogen 3.321 N/A GLN 183.A N MET 179.A O no hydrogen 2.892 N/A ASN 184.A N ILE 180.A O no hydrogen 2.860 N/A GLU 185.A N ASN 181.A O no hydrogen 2.969 N/A GLN 186.A N LYS 182.A O no hydrogen 2.874 N/A MET 187.A N GLN 183.A O no hydrogen 2.912 N/A HIS 188.A N ASN 184.A O no hydrogen 2.862 N/A ALA 189.A N GLU 185.A O no hydrogen 2.954 N/A LEU 190.A N GLN 186.A O no hydrogen 2.869 N/A LEU 191.A N MET 187.A O no hydrogen 2.900 N/A ALA 192.A N HIS 188.A O no hydrogen 2.921 N/A ILE 193.A N ALA 189.A O no hydrogen 2.871 N/A ALA 194.A N LEU 190.A O no hydrogen 2.963 N/A LEU 195.A N LEU 191.A O no hydrogen 2.840 N/A LEU 195.A N ALA 192.A O no hydrogen 3.136 N/A THR 196.A OG1 GLN 222.A OE1 no hydrogen 3.557 N/A THR 196.A OG1 ARG 281.A O no hydrogen 3.253 N/A TYR 198.A N LEU 195.A O no hydrogen 2.804 N/A SER 205.A OG ILE 202.A O no hydrogen 3.549 N/A ILE 206.A N ILE 202.A O no hydrogen 3.460 N/A GLN 209.A N GLN 209.A OE1 no hydrogen 2.855 N/A ARG 211.A NE HIS 207.A O no hydrogen 2.876 N/A ARG 211.A NH2 ILE 206.A O no hydrogen 2.364 N/A LYS 213.A N GLN 209.A O no hydrogen 2.997 N/A LYS 213.A NZ GLN 209.A O no hydrogen 3.170 N/A TYR 214.A N LEU 210.A O no hydrogen 2.925 N/A GLY 215.A N ARG 211.A O no hydrogen 2.813 N/A ASP 216.A N GLU 212.A O no hydrogen 2.976 N/A LYS 217.A N LYS 213.A O no hydrogen 2.986 N/A MET 218.A N TYR 214.A O no hydrogen 2.853 N/A LEU 219.A N GLY 215.A O no hydrogen 3.011 N/A ARG 220.A N ASP 216.A O no hydrogen 2.938 N/A ARG 220.A NE ASP 216.A O no hydrogen 3.070 N/A MET 221.A N MET 218.A O no hydrogen 3.056 N/A LYS 223.A NZ SER 282.A O no hydrogen 3.273 N/A GLU 230.A N PRO 226.A O no hydrogen 3.038 N/A GLU 231.A N GLN 227.A O no hydrogen 2.858 N/A LEU 232.A N VAL 228.A O no hydrogen 2.955 N/A PHE 233.A N TYR 229.A O no hydrogen 2.971 N/A SER 234.A N GLU 230.A O no hydrogen 2.910 N/A SER 234.A OG GLU 230.A O no hydrogen 3.258 N/A SER 234.A OG GLU 231.A O no hydrogen 3.140 N/A TYR 235.A N GLU 231.A O no hydrogen 2.923 N/A SER 236.A N LEU 232.A O no hydrogen 2.905 N/A SER 236.A N PHE 233.A O no hydrogen 3.329 N/A CYS 237.A N PHE 233.A O no hydrogen 2.924 N/A CYS 237.A SG PHE 233.A O no hydrogen 3.395 N/A CYS 237.A SG SER 234.A O no hydrogen 3.627 N/A LYS 239.A NZ GLN 186.A OE1 no hydrogen 3.158 N/A SER 242.A OG PRO 238.A O no hydrogen 2.347 N/A TYR 255.A OH THR 68.A OG1 no hydrogen 2.392 N/A HIS 256.A N ASN 254.A OD1 no hydrogen 2.665 N/A LYS 257.A N ASN 254.A OD1 no hydrogen 2.567 N/A LEU 261.A N LYS 257.A O no hydrogen 2.889 N/A GLN 262.A N GLU 258.A O no hydrogen 2.935 N/A GLN 263.A N PRO 259.A O no hydrogen 2.914 N/A GLN 263.A NE2 GLN 262.A OE1 no hydrogen 2.564 N/A LEU 264.A N PHE 260.A O no hydrogen 2.871 N/A PHE 267.A N GLN 263.A O no hydrogen 2.917 N/A SER 268.A N LEU 264.A O no hydrogen 2.845 N/A SER 268.A OG LEU 264.A O no hydrogen 2.944 N/A ASP 269.A N LYS 265.A O no hydrogen 2.997 N/A GLU 270.A N VAL 266.A O no hydrogen 2.995 N/A VAL 271.A N PHE 267.A O no hydrogen 2.831 N/A GLN 272.A N SER 268.A O no hydrogen 2.936 N/A GLN 272.A NE2 ASP 269.A O no hydrogen 3.544 N/A GLN 274.A N GLU 270.A O no hydrogen 2.984 N/A ALA 275.A N VAL 271.A O no hydrogen 2.832 N/A GLN 276.A N GLN 272.A O no hydrogen 2.888 N/A GLN 276.A NE2 HIS 315.A O no hydrogen 3.380 N/A LEU 277.A N GLN 273.A O no hydrogen 2.931 N/A SER 278.A N GLN 274.A O no hydrogen 2.939 N/A SER 278.A OG ILE 193.A O no hydrogen 2.419 N/A THR 279.A N ALA 275.A O no hydrogen 2.876 N/A THR 279.A OG1 ALA 275.A O no hydrogen 3.393 N/A THR 279.A OG1 GLN 276.A O no hydrogen 2.669 N/A ILE 280.A N GLN 276.A O no hydrogen 2.884 N/A ARG 281.A N LEU 277.A O no hydrogen 2.937 N/A SER 282.A N THR 279.A O no hydrogen 3.396 N/A SER 282.A OG THR 279.A O no hydrogen 2.896 N/A LEU 286.A N LEU 284.A O no hydrogen 2.850 N/A LEU 295.A N PRO 291.A O no hydrogen 2.829 N/A ALA 296.A N VAL 292.A O no hydrogen 2.915 N/A GLY 297.A N ALA 293.A O no hydrogen 2.931 N/A PHE 298.A N LYS 294.A O no hydrogen 2.836 N/A LEU 299.A N LEU 295.A O no hydrogen 2.848 N/A ASP 300.A N ALA 296.A O no hydrogen 3.001 N/A THR 302.A N PHE 298.A O no hydrogen 2.899 N/A THR 302.A OG1 PHE 298.A O no hydrogen 2.888 N/A THR 302.A OG1 LEU 299.A O no hydrogen 3.151 N/A THR 302.A OG1 GLU 303.A OE1 no hydrogen 2.608 N/A GLU 303.A N LEU 299.A O no hydrogen 2.988 N/A GLN 309.A N PHE 306.A O no hydrogen 2.972 N/A PHE 313.A N GLN 309.A O no hydrogen 2.953 N/A LYS 314.A N LEU 310.A O no hydrogen 2.928 N/A LYS 314.A NZ LEU 310.A O no hydrogen 3.106 N/A HIS 315.A N LEU 311.A O no hydrogen 2.921 N/A LYS 316.A N VAL 312.A O no hydrogen 2.879 N/A LYS 316.A N PHE 313.A O no hydrogen 3.261 N/A MET 317.A N PHE 313.A O no hydrogen 3.057 N/A MET 317.A N LYS 314.A O no hydrogen 3.311 N/A LYS 318.A N LYS 314.A O no hydrogen 2.856 N/A ASN 319.A ND2 GLN 276.A OE1 no hydrogen 3.545 N/A GLU 332.A N ASP 330.A OD1 no hydrogen 3.054 N/A GLN 334.A N SER 324.A OG no hydrogen 3.111 N/A ALA 336.A N GLN 334.A O no hydrogen 2.997 N/A ILE 348.A N ASP 344.A O no hydrogen 3.152 N/A HIS 349.A N LYS 345.A O no hydrogen 2.742 N/A HIS 349.A ND1 LYS 345.A O no hydrogen 2.526 N/A ILE 350.A N ASP 346.A O no hydrogen 2.941 N/A ALA 351.A N MET 347.A O no hydrogen 2.990 N/A ASP 352.A N ILE 348.A O no hydrogen 2.854 N/A THR 353.A N HIS 349.A O no hydrogen 2.899 N/A THR 353.A OG1 HIS 349.A O no hydrogen 2.773 N/A THR 353.A OG1 ILE 350.A O no hydrogen 3.044 N/A LYS 354.A N ILE 350.A O no hydrogen 2.868 N/A VAL 355.A N ALA 351.A O no hydrogen 2.949 N/A ALA 356.A N ASP 352.A O no hydrogen 2.895 N/A ARG 357.A N THR 353.A O no hydrogen 2.870 N/A ARG 358.A N LYS 354.A O no hydrogen 2.909 N/A TYR 359.A N VAL 355.A O no hydrogen 2.924 N/A GLY 360.A N ALA 356.A O no hydrogen 2.893 N/A ASP 361.A N ARG 357.A O no hydrogen 2.874 N/A PHE 362.A N ARG 358.A O no hydrogen 2.937 N/A PHE 363.A N TYR 359.A O no hydrogen 2.901 N/A ILE 364.A N GLY 360.A O no hydrogen 2.906 N/A ARG 365.A N ASP 361.A O no hydrogen 2.951 N/A GLN 366.A N PHE 362.A O no hydrogen 2.933 N/A ILE 367.A N PHE 363.A O no hydrogen 2.909 N/A HIS 368.A N ILE 364.A O no hydrogen 2.916 N/A LYS 369.A N ARG 365.A O no hydrogen 2.962 N/A PHE 370.A N ILE 367.A O no hydrogen 3.267 N/A GLU 371.A N ILE 367.A O no hydrogen 2.912 N/A GLU 372.A N HIS 368.A O no hydrogen 3.229 N/A