|
83
|
263
|
6nnrA |
High-resolution structure of wild-type e. coli thymidylate synthase |
|
95
|
289
|
5hs3A |
Human thymidylate synthase complexed with dump and 3-amino-2-benzoyl-4-methylthieno[2,3-b]pyridin-6-ol |
|
90
|
281
|
5h3aA |
Structural analysis of kshv thymidylate synthase |
|
76
|
262
|
6cdzA |
E. coli thymidylate synthase mutant i264am |
|
72
|
252
|
6aujA |
Crystal structure of thymidylate synthase from elizabethkingia anophelis nuhp1 |
|
144
|
564
|
6aohA |
Crystal structure of toxoplasma gondii ts-dhfr complexed with nadph, dump, pddf, and 5-(4-(3-(2-methoxypyrimidin-5-yl)phenyl)piperazin-1-yl)pyrimidine-2,4-diamine (trc-2533) |
|
158
|
564
|
6aogA |
Crystal structure of toxoplasma gondii ts-dhfr complexed with nadph, dump, pddf, and 5-(4-chlorophenyl)-6-ethylpyrimidine-2,4-diamine (pyrimethamine) |
|
154
|
564
|
6aoiA |
Crystal structure of toxoplasma gondii ts-dhfr complexed with nadph, dump, pddf, and 5-(4-phenylpiperazin-1-yl)-6-propylpyrimidine-2,4-diamine (trc-2528) |
|
82
|
284
|
5x4xA |
Mutant human thymidylate synthase a191k crystallized in a sulfate-containing condition |
|
72
|
261
|
4f2vA |
Crystal structure of de novo designed serine hydrolase, northeast structural genomics consortium (nesg) target or165 |
|
95
|
287
|
4ez8A |
Crystal structure of mouse thymidylate sythase in ternary complex with n(4)-hydroxy-2'-deoxycytidine-5'-monophosphate and the cofactor product, dihydrofolate |
|
99
|
307
|
4eb4A |
Crystal structure of mouse thymidylate synthase in ternary complex with dump and tomudex |
|
100
|
312
|
4dq1A |
Thymidylate synthase from staphylococcus aureus. |
|
108
|
608
|
4eckA |
Crystal structure of the toxoplasma gondii ts-dhfr |
|
182
|
606
|
4dp3A |
Quadruple mutant (n51i+c59r+s108n+i164l) plasmodium falciparum dihydrofolate reductase-thymidylate synthase (pfdhfr-ts) complexed with p218 and nadph |
|
67
|
286
|
4e28A |
Structure of human thymidylate synthase in inactive conformation with a novel non-peptidic inhibitor |
|
93
|
285
|
4einA |
Crystal structure of mouse thymidylate synthase in binary complex with a substrate analogue and strong inhibitor, n(4)-hydroxy-2'-deoxycytidine-5'-monophosphate |
|
173
|
606
|
4dphA |
Quadruple mutant (n51i+c59r+s108n+i164l) plasmodium falciparum dihydrofolate reductase-thymidylate synthase (pfdhfr-ts) complexed with p65 and nadph |
|
94
|
287
|
4e5oA |
Crystal structure of mouse thymidylate synthase in complex with dump |
|
171
|
563
|
4eilA |
Crystal structure of the loop truncated toxoplasma gondii ts-dhfr |
|
98
|
314
|
3v8hA |
Crystal structure of thymidylate synthase from burkholderia thailandensis |
|
104
|
315
|
3uwlB |
Crystal structure of enteroccocus faecalis thymidylate synthase (efts) in complex with 5-formyl tetrahydrofolate |
|
168
|
608
|
3um6A |
Double mutant (a16v+s108t) plasmodium falciparum dhfr-ts (t9/94) complexed with cycloguanil, nadph and dump |
|
92
|
313
|
3uwlA |
Crystal structure of enteroccocus faecalis thymidylate synthase (efts) in complex with 5-formyl tetrahydrofolate |
|
177
|
608
|
3um5A |
Double mutant (a16v+s108t) plasmodium falciparum dihydrofolate reductase-thymidylate synthase (pfdhfr-ts-t9/94) complexed with pyrimethamine, nadph, and dump |
|
78
|
264
|
3tmsA |
Plastic adaptation toward mutations in proteins: structural comparison of thymidylate synthases |
|
58
|
218
|
3rg9A |
Trypanosoma brucei dihydrofolate reductase (tbdhfr) in complex with wr99210 |
|
96
|
288
|
5x5dA |
Human thymidylate synthase bound with dump |
|
94
|
288
|
5x66A |
Human thymidylate synthase in complex with dump and methotrexate |
|
92
|
287
|
5x69A |
Human thymidylate synthase with a fragment bound in the dimer interface |
|
94
|
287
|
5x5aA |
Human thymidylate synthase bound with phosphate ion |
|
87
|
285
|
5x4yA |
Mutant human thymidylate synthase m190k crystallized in a sulfate-containing condition |
|
96
|
286
|
5x5qA |
Human thymidylate synthase complexed with dump and raltitrexed |
|
95
|
286
|
5x67A |
Human thymidylate synthase in complex with dump and nolatrexed |
|
86
|
286
|
5x4wA |
Mutant human thymidylate synthase a191k crystallized in a sulfate-free condition |
|
97
|
284
|
5wrnA |
Human thymidylate synthase complexed with dcmp |
|
156
|
563
|
5t0lA |
Crystal structure of toxoplasma gondii ts-dhfr complexed with nadph, dump, pddf and 5-(4-(3,4-dichlorophenyl)piperazin-1-yl)pyrimidine-2,4-diamine (trc-15) |
|
88
|
287
|
5nooA |
Crystal structure of c.elegans thymidylate synthase in complex with dump and tomudex |
|
98
|
284
|
5by6A |
Crystal structure of trichinella spiralis thymidylate synthase complexed with dump |
|
77
|
313
|
5j7wA |
Enterococcus faecalis thymidylate synthase complex with methotrexate |
|
89
|
283
|
5h38A |
Structural analysis of kshv thymidylate synthase |
|
94
|
285
|
5h39A |
Structural analysis of kshv thymidylate synthase |
|
96
|
287
|
5fctA |
Mouse thymidylate synthase in ternary complex with fdump and methylenetetrahydrofolate. |
|
77
|
279
|
4xseA |
Complex structure of thymidylate synthase from varicella zoster virus |
|
81
|
280
|
4xscA |
Complex structure of thymidylate synthase from varicella zoster virus with a phosphorylated bvdu |
|
64
|
281
|
4xsdA |
Complex structure of thymidylate synthase from varicella zoster virus with a dump |
|
87
|
283
|
4up1A |
Crystal structure of native human thymidylate synthase in active form |
|
103
|
316
|
4tmsA |
Plastic adaptation toward mutations in proteins: structural comparison of thymidylate synthases |
|
162
|
519
|
4q0dA |
Crystal structure of ts-dhfr from cryptosporidium hominis in complex with nadph, fdump, methotrexate and 2-amino-4-oxo-4,7-dihydro-pyrrolo[2,3-d]pyrimidine-methyl-phenyl-l-glutamic acid. |
|
157
|
519
|
4q0eA |
Crystal structure of ts-dhfr from cryptosporidium hominis in complex with nadph, fdump and 2-amino-4-oxo-4,7-dihydro-pyrrolo[2,3-d]pyrimidine-methyl-phenyl-l-glutamic acid. |
