93
|
323
|
8f1xA |
Egfr kinase in complex with mobocertinib (tak-788) |
88
|
322
|
8g63A |
Ralimetinib (ly2228820) in complex with wild type egfr |
69
|
308
|
8emeA |
Egfr(t790m/v948r) in complex with znl-0056 |
103
|
328
|
8dswA |
Crystal structure of egfr kinase domain, exon20 insertion fqea mutant |
93
|
322
|
7zynA |
Crystal structure of egfr-t790m/c797s in complex with wz4002 |
82
|
285
|
7zyqA |
Crystal structure of egfr-t790m/v948r in complex with reversible aminopyrimidine 13 |
87
|
325
|
7zypA |
Crystal structure of egfr-t790m/c797s in complex with reversible aminopyrimidine 9 |
93
|
325
|
7zymA |
Crystal structure of egfr-t790m/c797s in complex with brigatinib |
3
|
47
|
8hgsC |
The egf-bound egfr ectodomain homodimer |
97
|
593
|
8hgsA |
The egf-bound egfr ectodomain homodimer |
91
|
321
|
7t4iA |
Crystal structure of wild type egfr in complex with tak-788 |
85
|
287
|
7t4jA |
Crystal structure of egfr_d770_n771insnpg/v948r in complex with tak-788 |
94
|
325
|
7u99A |
Egfr kinase in complex with a macrocyclic inhibitor |
89
|
325
|
7u9aA |
Egfr in complex with a macrocyclic inhibitor |
88
|
323
|
7ukvA |
Wild type egfr in complex with lazertinib (yh25448) |
84
|
307
|
7u98A |
Egfr(t790m/v948r) in complex with a macrocyclic inhibitor |
95
|
313
|
7ukwA |
Egfr(t790m/v948r) in complex with lazertinib (yh25448) |
99
|
327
|
7si1A |
Crystal structure of apo egfr kinase domain |
84
|
289
|
8a2bA |
Egfr kinase domain (l858r/v948r) in complex with 2-(6,7-dihydro-5h-pyrrolo[1,2-c]imidazol-1-yl)-2-[6-[2-[4-[[4-(hydroxymethyl)-1-piperidyl]methyl]phenyl]ethynyl]-1-oxo-4-(trifluoromethyl)isoindolin-2-yl]-n-thiazol-2-yl-acetamide |
93
|
321
|
8a2dA |
Egfr kinase domain (l858r/v948r) in complex with 2-[4-(difluoromethyl)-6-[2-[4-[[4-(hydroxymethyl)-1-piperidyl]methyl]phenyl]ethynyl]-7-methyl-indazol-2-yl]-2-spiro[6,7-dihydropyrrolo[1,2-c]imidazole-5,1'-cyclopropane]-1-yl-n-thiazol-2-yl-acetamide |
89
|
285
|
8a27A |
Egfr kinase domain in complex with 2-(6,7-dihydro-5h-pyrrolo[1,2-c]imidazol-1-yl)-2-[6-[2-[4-[[4-(hydroxymethyl)-1-piperidyl]methyl]phenyl]ethynyl]-1-oxo-4-(trifluoromethyl)isoindolin-2-yl]-n-thiazol-2-yl-acetamide |
100
|
320
|
8a2aA |
Egfr kinase domain in complex with 2-(6,7-dihydro-5h-pyrrolo[1,2-c]imidazol-1-yl)-2-[6-[2-[4-[[4-(hydroxymethyl)-1-piperidyl]methyl]phenyl]ethynyl]-1-oxo-4-(trifluoromethyl)isoindolin-2-yl]-n-thiazol-2-yl-acetamide (form 2) |
99
|
309
|
8d73A |
Crystal structure of egfr lrtm with compound 7 |
106
|
312
|
8d76A |
Crystal structure of egfr lrtm with compound 24 |
86
|
325
|
7oxbA |
Crystal structure of egfr double mutant (t790m/l858r) in complex with compound 6. |
79
|
286
|
7lgsA |
Structure of egfr_d770_n771insnpg/v948r in complex with covalent inhibitor osimertinib. |
94
|
308
|
7jxpA |
Egfr kinase (t790m/v948r) in complex with osimertinib and jbj-04-125-02 |
86
|
308
|
7k1iA |
Egfr kinase (l858r/v948r) in complex with allosteric inhibitor jbj-09-063 |
94
|
308
|
7jxqA |
Egfr kinase (t790m/v948r) in complex with allosteric inhibitor jbj-09-063 |
88
|
308
|
7jxmA |
Egfr kinase (t790m/v948r) in complex with osimertinib and eai045 |
86
|
308
|
7jxwA |
Egfr kinase (t790m/v948r) in complex with osimertinib and jbj-09-063 |
85
|
313
|
7jxlA |
Egfr kinase (t790m/v948r) in complex with az5104 |
89
|
307
|
7k1hA |
Egfr l858r/v948r in complex with osimertinib and allosteric inhibitor jbj-09-063 |
88
|
308
|
7jxkA |
Egfr kinase (t790m/v948r) in complex with pf-06747775 and jbj-04-125-02 |
88
|
307
|
7jxiA |
Egfr kinase (t790m/v948r) in complex with pf-06747775 |
90
|
308
|
6xl4A |
Egfr(t790m/v948r) in complex with azd9291 and ddc4002 |
86
|
322
|
7aeiA |
Studies towards a reversible egfr c797s triple mutant inhibitor series |
92
|
316
|
6wxnA |
Egfr(t790m/v948r) in complex with ln3844 |
93
|
324
|
7aemA |
Studies towards a reversible egfr c797s triple mutant inhibitor series |
91
|
316
|
6wa2A |
Crystal structure of egfr(t790m/v948r) in complex with ln3753 |
92
|
312
|
6wakA |
A crystal structure of egfr(t790m/v948r) in complex with ln3754 |
78
|
285
|
7a2aA |
Crystal structure of egfr-t790m/v948r in complex with spebrutinib and eai001 |
81
|
283
|
6z4bA |
Crystal structure of egfr-t790m/v948r in complex with osimertinib and eai045 |
83
|
284
|
6z4dA |
Crystal structure of egfr-t790m/v948r in complex with mavelertinib and eai001 |
92
|
323
|
6ludA |
Crystal structure of egfr(l858r/t790m/c797s) in complex with osimertinib |
92
|
323
|
6lubA |
Crystal structure of egfr(l858r/t790m/c797s) in complex with ch7233163 |
84
|
286
|
6tfvA |
Crystal structure of egfr t790m/v948r in complex with covalent pyrrolopyrimidine 18b |
84
|
282
|
6tfzA |
Crystal structure of egfr t790m/v948r in complex with covalent pyrrolopyrimidine 19 |
85
|
286
|
6tg0A |
Crystal structure of egfr t790m/v948r in complex with covalent pyrrolopyrimidine 21a |
77
|
283
|
6tfuA |
Crystal structure of egfr t790m/v948r in complex with covalent pyrrolopyrimidine 14d |