Found 176 chains in Genus chains table. Displaying 51 - 100. Applied filters: Proteins

Search results query: mitogen-activated protein kinase 1

Total Genus Sequence Length pdb Title
110 347 6g93A Fragment-based discovery of a highly potent, orally bioavailable inhibitor which modulates the phosphorylation and catalytic activity of erk1/2
110 350 6g91A Fragment-based discovery of a highly potent, orally bioavailable inhibitor which modulates the phosphorylation and catalytic activity of erk1/2
104 347 6g8xA Fragment-based discovery of a highly potent, orally bioavailable inhibitor which modulates the phosphorylation and catalytic activity of erk1/2
111 347 6g9nA Fragment-based discovery of a highly potent, orally bioavailable inhibitor which modulates the phosphorylation and catalytic activity of erk1/2
115 346 6g9mA Fragment-based discovery of a highly potent, orally bioavailable inhibitor which modulates the phosphorylation and catalytic activity of erk1/2
102 349 6gdmA Fragment-based discovery of a highly potent, orally bioavailable inhibitor which modulates the phosphorylation and catalytic activity of erk1/2
113 350 6g92A Fragment-based discovery of a highly potent, orally bioavailable inhibitor which modulates the phosphorylation and catalytic activity of erk1/2
110 347 6g9hA Fragment-based discovery of a highly potent, orally bioavailable inhibitor which modulates the phosphorylation and catalytic activity of erk1/2
108 350 6g9dA Fragment-based discovery of a highly potent, orally bioavailable inhibitor which modulates the phosphorylation and catalytic activity of erk1/2
111 347 6g97A Fragment-based discovery of a highly potent, orally bioavailable inhibitor which modulates the phosphorylation and catalytic activity of erk1/2
105 350 6g9jA Fragment-based discovery of a highly potent, orally bioavailable inhibitor which modulates the phosphorylation and catalytic activity of erk1/2
108 339 6dcgA Discovery of mk-8353: an orally bioavailable dual mechanism erk inhibitor for oncology
108 340 6cpwA Discovery of 3(s)-thiomethyl pyrrolidine erk inhibitors for oncology
111 348 5buiA Erk2 complexed with 2-pyridiyl tetrahydroazaindazole
115 350 5bvdA Tetrahydropyrrolo-diazepenones as inhibitors of erk2 kinase
109 350 5bujA Erk2 complexed with a n-h tetrahydroazaindazole
107 350 5bvfA Tetrahydropyrrolo-diazepenones as inhibitors of erk2 kinase
109 348 5bueA Erk2 complexed with n-benzylpyridone tetrahydroazaindazole
111 345 4zzoA Human erk2 in complex with an irreversible inhibitor
114 345 4zznA Human erk2 in complex with an inhibitor
123 348 4qteA Structure of erk2 in complex with vtx-11e, 4-{2-[(2-chloro-4-fluorophenyl)amino]-5-methylpyrimidin-4-yl}-n-[(1s)-1-(3-chlorophenyl)-2-hydroxyethyl]-1h-pyrrole-2-carboxamide
113 359 3zuvA Crystal structure of a designed selected ankyrin repeat protein in complex with the phosphorylated map kinase erk2
102 344 3zu7A Crystal structure of a designed selected ankyrin repeat protein in complex with the map kinase erk2
36 122 3zuvB Crystal structure of a designed selected ankyrin repeat protein in complex with the phosphorylated map kinase erk2
52 154 3zu7B Crystal structure of a designed selected ankyrin repeat protein in complex with the map kinase erk2
86 347 3w55A The structure of erk2 in complex with fr148083
101 349 3teiA Crystal structure of human erk2 complexed with a mapk docking peptide
2 17 3teiB Crystal structure of human erk2 complexed with a mapk docking peptide
110 343 5wp1A Complex of erk2 with 5,7-dihydroxychromone
2 14 5v62I Phospho-erk2 bound to bivalent inhibitor sbp3
116 351 5v62A Phospho-erk2 bound to bivalent inhibitor sbp3
115 350 5v61A Phospho-erk2 bound to bivalent inhibitor sbp2
1 17 5v61I Phospho-erk2 bound to bivalent inhibitor sbp2
113 349 5v60A Phospho-erk2 bound to amp-pcp
109 351 5umoA Structure of extracellular signal-regulated kinase
114 340 5u6iA Discovery of mli-2, an orally available and selective lrrk2 inhibitor that reduces brain kinase activity
110 345 5nhoA Human erk2 with an erk1/2 inhibitor
113 345 5nhjA Human erk2 with an erk1/2 inhibitor
109 344 5nhfA Human erk2 with an erk1/2 inhibitor
114 345 5nhpA Human erk2 with an erk1/2 inhibitor
101 345 5nguA Human erk2 with an erk1/2 inhibitor
108 347 5lckA A clickable covalent erk 1/2 inhibitor
111 340 5ke0A Discovery of 1-1h-pyrazolo 4,3-c pyridine-6-yl urea inhibitors of extracellular signal regulated kinase erk for the treatment of cancers
114 350 5bveA Tetrahydropyrrolo-diazepenones as inhibitors of erk2 kinase
107 351 4zxtA Complex of erk2 with catechol
115 347 5hd7A Dissecting therapeutic resistance to erk inhibition rat mutant sch772984 in complex with (3r)-1-(2-oxo-2-{4-[4-(pyrimidin-2-yl)phenyl]piperazin-1-yl}ethyl)-n-[3-(pyridin-4-yl)-2h-indazol-5-yl]pyrrolidine-3-carboxamide
108 345 4zzmA Human erk2 in complex with an irreversible inhibitor
71 349 5ax3A Crystal structure of erk2 complexed with allosteric and atp-competitive inhibitors.
113 345 4xrlA Crystal structure at room temperature of erk2 in complex with an inhibitor
104 349 4xj0A Crystal structure of erk2 in complex with an inhibitor 14k