86
|
318
|
6bgzA |
Linked kdm5a jmj domain bound to the inhibitor 2-((2-chlorophenyl)(2-(1-methyl-1h-imidazol-2-yl)ethoxy)methyl)-1h-pyrrolo[3,2-b]pyridine-7-carboxylic acid (compound n47) |
88
|
317
|
6bh5A |
Linked kdm5a jmj domain bound to the inhibitor 2-((2-chlorophenyl)(3-(piperidin-1-yl)propoxy)methyl)-1h-pyrrolo[3,2-b]pyridine-7-carboxylic acid (compound n48) |
88
|
318
|
6bgvA |
Linked kdm5a jmj domain bound to the inhibitor 2-((2-chlorophenyl)(2-(piperidin-1-yl)ethoxy)methyl)-1l2-pyrrolo[3,2-b]pyridine-7-carboxylic acid (compound n40) |
84
|
318
|
6bh4A |
Linked kdm5a jmj domain bound to the inhibitor 5-(1-(tert-butyl)-1h-pyrazol-4-yl)-6-isopropyl-7-oxo-4,7-dihydropyrazolo[1,5-a]pyrimidine-3-carbonitrile (compound n75/cpi-48) |
87
|
318
|
6bgwA |
Linked kdm5a jmj domain bound to the inhibitor 2-((2-chlorophenyl)(2-(4,4-difluoropiperidin-1-yl)ethoxy)methyl)-1h-pyrrolo[3,2-b]pyridine-7-carboxylic acid(compound n41) |
86
|
318
|
6bh1A |
Linked kdm5a jmj domain bound to the inhibitor (s)-2-((2-chlorophenyl)(2-(piperidin-1-yl)ethoxy)methyl)-1l2-pyrrolo[3,2-b]pyridine-7-carboxylic acid (compound n52) |
148
|
547
|
5yknA |
Crystal structure of arabidopsis thaliana jmj14 catalytic domain |
158
|
547
|
5ykoA |
Crystal structure of arabidopsis thaliana jmj14 catalytic domain in complex with nog and h3k4me3 peptide |
105
|
345
|
5vgiA |
Crystal structure of kdm4 with the small molecule inhibitor qc6352 |
108
|
350
|
5vmpA |
Crystal structure of human kdm4 with small molecule inhibitor qc5714 |
107
|
350
|
5f37A |
Crystal structure of human kdm4a in complex with compound 58 |
161
|
774
|
5cehA |
Structure of histone lysine demethylase kdm5a in complex with selective inhibitor |
145
|
462
|
5a3nA |
Crystal structure of human plu-1 (jarid1b) in complex with kdoam25a |
144
|
463
|
5a3pA |
Crystal structure of the catalytic domain of human plu1 (jarid1b). |
144
|
458
|
5a1fA |
Crystal structure of the catalytic domain of plu1 in complex with n-oxalylglycine. |
150
|
462
|
5a3tA |
Crystal structure of human plu-1 (jarid1b) in complex with kdm5-c49 (2-(((2-((2-(dimethylamino)ethyl)(ethyl)amino)-2-oxoethyl)amino)methyl) isonicotinic acid). |
109
|
349
|
4uraA |
Crystal structure of human jmjd2a in complex with compound 14a |
99
|
327
|
4d6sA |
Crystal structure of human jmjd2d in complex with n-oxalylglycine and bound 5,6-dimethylbenzimidazole |
100
|
323
|
4d6rA |
Crystal structure of human jmjd2d in complex with n-oxalylglycine and bound o-toluenesulfonamide |
104
|
330
|
4d6qA |
Crystal structure of human jmjd2d in complex with 2,4-pdca |
103
|
348
|
4bisA |
Jmjd2a complexed with 8-hydroxyquinoline-4-carboxylic acid |
107
|
348
|
4ai9A |
Jmjd2a complexed with daminozide |
106
|
345
|
3u4sA |
Histone lysine demethylase jmjd2a in complex with t11c peptide substrate crosslinked to n-oxalyl-d-cysteine |
107
|
351
|
3rvhA |
Crystal structure of jmjd2a complexed with inhibitor |
106
|
345
|
2q8cA |
Crystal structure of jmjd2a in ternary complex with an histone h3k9me3 peptide and 2-oxoglutarate |
105
|
344
|
2q8eA |
Specificity and mechanism of jmjd2a, a trimethyllysine-specific histone demethylase |
100
|
347
|
2q8dA |
Crystal structure of jmj2d2a in ternary complex with histone h3-k36me2 and succinate |
147
|
774
|
5v9tA |
Crystal structure of selective pyrrolidine amide kdm5a inhibitor n-{(3r)-1-[3-(propan-2-yl)-1h-pyrazole-5-carbonyl]pyrrolidin-3-yl}cyclopropanecarboxamide (compound 48) |
158
|
774
|
5v9pA |
Crystal structure of pyrrolidine amide inhibitor [(3s)-3-(4-bromo-1h-pyrazol-1-yl)pyrrolidin-1-yl][3-(propan-2-yl)-1h-pyrazol-5-yl]methanone (compound 35) in complex with kdm5a |
107
|
348
|
5tvrA |
Jmjd2a in complex with ni(ii) and alpha-ketoglutarate |
104
|
348
|
5tvsA |
Jmjd2a in complex with ni(ii) |
104
|
331
|
5pirA |
Pandda analysis group deposition -- crystal structure of jmjd2d after initial refinement with no ligand modelled (structure 40) |
105
|
331
|
5pmwA |
Pandda analysis group deposition -- crystal structure of jmjd2d after initial refinement with no ligand modelled (structure 190) |
104
|
331
|
5pivA |
Pandda analysis group deposition -- crystal structure of jmjd2d after initial refinement with no ligand modelled (structure 44) |
105
|
331
|
5pk1A |
Pandda analysis group deposition -- crystal structure of jmjd2d after initial refinement with no ligand modelled (structure 86) |
104
|
330
|
5phhA |
Pandda analysis group deposition -- crystal structure of jmjd2d in complex with n09457a |
106
|
331
|
5pm9A |
Pandda analysis group deposition -- crystal structure of jmjd2d after initial refinement with no ligand modelled (structure 167) |
103
|
331
|
5pjwA |
Pandda analysis group deposition -- crystal structure of jmjd2d after initial refinement with no ligand modelled (structure 81) |
104
|
331
|
5pjqA |
Pandda analysis group deposition -- crystal structure of jmjd2d after initial refinement with no ligand modelled (structure 75) |
103
|
331
|
5pktA |
Pandda analysis group deposition -- crystal structure of jmjd2d after initial refinement with no ligand modelled (structure 114) |
107
|
331
|
5ph5A |
Pandda analysis group deposition -- crystal structure of jmjd2d in complex with n09724a |
103
|
331
|
5pidA |
Pandda analysis group deposition -- crystal structure of jmjd2d after initial refinement with no ligand modelled (structure 26) |
103
|
331
|
5pk7A |
Pandda analysis group deposition -- crystal structure of jmjd2d after initial refinement with no ligand modelled (structure 92) |
104
|
331
|
5plpA |
Pandda analysis group deposition -- crystal structure of jmjd2d after initial refinement with no ligand modelled (structure 146) |
105
|
331
|
5phcA |
Pandda analysis group deposition -- crystal structure of jmjd2d in complex with n09649a |
104
|
331
|
5phkA |
Pandda analysis group deposition -- crystal structure of jmjd2d in complex with n09720a |
104
|
331
|
5pjkA |
Pandda analysis group deposition -- crystal structure of jmjd2d after initial refinement with no ligand modelled (structure 69) |
103
|
331
|
5phuA |
Pandda analysis group deposition -- crystal structure of jmjd2d after initial refinement with no ligand modelled (structure 7) |
104
|
331
|
5pkaA |
Pandda analysis group deposition -- crystal structure of jmjd2d after initial refinement with no ligand modelled (structure 95) |
103
|
331
|
5pj9A |
Pandda analysis group deposition -- crystal structure of jmjd2d after initial refinement with no ligand modelled (structure 58) |