19
|
99
|
6dh7A |
Crystal structure of hiv-1 protease nl4-3 i50v mutant in complex with umass1 |
17
|
99
|
6dh5A |
Crystal structure of hiv-1 protease nl4-3 v82i mutant in complex with umass6 |
18
|
99
|
6dh0A |
Crystal structure of hiv-1 protease nl4-3 i84v mutant in complex with darunavir |
17
|
99
|
6dh1A |
Crystal structure of hiv-1 protease nl4-3 i84v mutant in complex with umass1 |
19
|
99
|
6dgxA |
Crystal structure of hiv-1 protease nl4-3 wt in complex with darunavir |
18
|
99
|
6dh3A |
Crystal structure of hiv-1 protease nl4-3 v82i mutant in complex with darunavir |
19
|
99
|
6dh4A |
Crystal structure of hiv-1 protease nl4-3 v82i mutant in complex with umass1 |
18
|
99
|
6dgzA |
Crystal structure of hiv-1 protease nl4-3 wt in complex with umass6 |
20
|
99
|
6d0eA |
X-ray crystal structure of wild type hiv-1 protease in complex with grl-084-13 |
20
|
99
|
6mcrA |
X-ray crystal structure of wild type hiv-1 protease in complex with grl-001 |
19
|
99
|
6mcsA |
X-ray crystal structure of wild type hiv-1 protease in complex with grl-003 |
20
|
99
|
6d0dA |
X-ray crystal structure of wild type hiv-1 protease in complex with grl-087-13 |
18
|
99
|
3sa7A |
Crystal structure of wild-type hiv-1 protease in complex with af55 |
19
|
99
|
3sa5A |
Crystal structure of wild-type hiv-1 protease in complex with af69 |
16
|
99
|
3s85A |
Discovery of new hiv protease inhibitors with potential for convenient dosing and reduced side effects: a-790742 and a-792611. |
18
|
99
|
3sacA |
Crystal structure of wild-type hiv-1 protease in complex with af80 |
18
|
99
|
3sa4A |
Crystal structure of wild-type hiv-1 protease in complex with af72 |
18
|
99
|
3saaA |
Crystal structure of wild-type hiv-1 protease in complex with af77 |
18
|
99
|
3sa8A |
Crystal structure of wild-type hiv-1 protease in complex with kb83 |
18
|
99
|
3sa6A |
Crystal structure of wild-type hiv-1 protease in complex with af71 |
18
|
99
|
3sa3A |
Crystal structure of wild-type hiv-1 protease in complex with ag23 |
17
|
99
|
5kqzA |
Protease e35d-cap2 |
19
|
99
|
5kr0A |
Protease e35d-apv |
16
|
99
|
5kr1A |
Protease pr5-drv |
17
|
99
|
5kqxA |
Protease e35d-sqv |
18
|
99
|
5jfuA |
Hiv-1 wild type protease with grl-007-14a (a adamantane p1-ligand with bis-thf in p2 and benzylamine in p1') |
18
|
99
|
5jfpA |
Hiv-1 wild type protease with grl-097-13a (a adamantane p1-ligand with bis-thf in p2 and isobutylamine in p1') |
18
|
99
|
5ivtA |
Crystal structure of hiv protease complexed with [(1s)-1-[(s)-(4-chlorophenyl)-(3,5-difluorophenyl)methyl]-2-[[5-fluoro-4-[2-[(2r,5s)-5-(2,2,2-trifluoroethylcarbamoyloxymethyl)morpholin-4-ium-2-yl]ethyl]pyridin-1-ium-3-yl]amino]-2-oxo-ethyl]ammonium |
18
|
99
|
5ivrA |
Crystal structure of hiv protease complexed with methyl n-[(1s)-1-[[2-[(3s)-3-[(4-aminophenyl)methylamino]-4-hydroxy-butyl]phenyl]carbamoyl]-2,2-diphenyl-ethyl]carbamate |
16
|
99
|
5ivqA |
Crystal structure of hiv protease complexed with methyl n-[(1s)-1-benzhydryl-2-(3-morpholin-4-ium-2-ylpropylamino)-2-oxo-ethyl]carbamate |
16
|
99
|
5hvpA |
Crystallographic analysis of a complex between human immunodeficiency virus type 1 protease and acetyl-pepstatin at 2.0-angstroms resolution |
14
|
99
|
7upjA |
Hiv-1 protease/u101935 complex |
17
|
99
|
9hvpA |
Design, activity and 2.8 angstroms crystal structure of a c2 symmetric inhibitor complexed to hiv-1 protease |
12
|
99
|
8hvpA |
Structure at 2.5-angstroms resolution of chemically synthesized human immunodeficiency virus type 1 protease complexed with a hydroxyethylene*-based inhibitor |
14
|
99
|
7hvpA |
X-ray crystallographic structure of a complex between a synthetic protease of human immunodeficiency virus 1 and a substrate-based hydroxyethylamine inhibitor |
16
|
99
|
6upjA |
Hiv-2 protease/u99294 complex |
29
|
112
|
6fivA |
Structural studies of hiv and fiv proteases complexed with an efficient inhibitor of fiv pr |
20
|
99
|
6cdlA |
Hiv-1 wild type protease with grl-03214a, 6-5-5-ring fused umbrella-like tetrahydropyranofuran as the p2-ligand, a cyclopropylaminobenzothiazole as the p2'-ligand and 3,5-difluorophenylmethyl as the p1-ligand |
19
|
99
|
6cdjA |
Hiv-1 wild type protease with grl-03314a, 6-5-5-ring fused umbrella-like tetrahydropyranofuran as the p2-ligand, a cyclopropylaminobenzothiazole as the p2'-ligand and 3,5-difluorophenylmethyl as the p1-ligand |
19
|
99
|
6bz2A |
Crystal structure of wild-type hiv-1 protease with a novel hiv-1 inhibitor grl-14213a of 6-5-5-ring fused crown-like tetrahydropyranofuran as the p2-ligand, a cyclopropylaminobenzothiazole as the p2'-ligand and 3,5-difluorophenylmethyl as the p1-ligand |
19
|
99
|
6braA |
Hiv-1 protease (d25n, inactive) in complex with phage display optimized substrate sgiflets |
18
|
99
|
6b36A |
Crystal structure of hiv protease complexed with (s)-n-(3-fluoro-2-(2-(1-(phenylsulfonyl)piperazin-2-yl)ethyl)phenyl)-3,3-bis(4-fluorophenyl)propanamide |
18
|
99
|
6b3hA |
Crystal structure of hiv protease complexed with n-(2-(2-((6r,9s)-2,2-dioxido-2-thia-1,7-diazabicyclo[4.3.1]decan-9-yl)ethyl)-3-fluorophenyl)-3,3-bis(4-fluorophenyl)propanamide |
16
|
99
|
6b38A |
Crystal structure of hiv protease complexed with n-(3-fluoro-2-(2-((2s,6r)-6-methyl-1-(phenylsulfonyl)piperazin-2-yl)ethyl)phenyl)-3,3-bis(4-fluorophenyl)propanamide |
16
|
99
|
6b3cA |
Crystal structure of hiv protease complexed with n-(3-fluoro-2-(2-((2s,6r)-6-methyl-1-(phenylsulfonyl)piperazin-2-yl)ethyl)phenyl)-3,3-bis(4-fluorophenyl)propanamide |
18
|
99
|
6b3fA |
Crystal structure of hiv protease complexed with n-(3-fluoro-2-(2-((2s,5s)-5-methyl-1-(phenylsulfonyl)piperazin-2-yl)ethyl)phenyl)-3,3-bis(4-fluorophenyl)propanamide |
17
|
99
|
6b3gA |
Crystal structure of hiv protease complexed with n-(3-fluoro-2-(2-((2s,6s)-6-methyl-1-(phenylsulfonyl)piperazin-2-yl)ethyl)phenyl)-3,3-bis(4-fluorophenyl)propanamide |
19
|
99
|
6b4nA |
A hydroxymethyl functionality at the 4-position of the 2-phenyloxazole moiety of hiv-1 protease inhibitors involving the p2' ligands |
18
|
99
|
5yrsA |
X-ray snapshot of hiv-1 protease in action: observation of tetrahedral intermediate and its sihb with catalytic aspartate |
17
|
99
|
5yokA |
Structure of hiv-1 protease in complex with inhibitor kni-1657 |