|
156
|
522
|
6mdaA |
Non-receptor protein tyrosine phosphatase shp2 in complex with allosteric inhibitor pyrazolo-pyridine 4 |
|
157
|
523
|
6mdbA |
Non-receptor protein tyrosine phosphatase shp2 in complex with allosteric inhibitor pyrazolo-pyrimidinone 5 |
|
24
|
101
|
3s8oA |
Crystal structure of the grb2 sh2 domain in complex with a pyxn-derived tripeptide |
|
21
|
114
|
3s9kA |
Crystal structure of the itk sh2 domain. |
|
23
|
101
|
3s8nA |
Crystal structure of the grb2 sh2 domain in complex with a pyxn-derived tripeptide |
|
64
|
272
|
5sxaB |
Crystal structure of pi3kalpha in complex with fragment 10 |
|
78
|
271
|
5sxkB |
Crystal structure of pi3kalpha in complex with fragment 18 |
|
19
|
90
|
5mtnA |
Monobody mb(lck_1) bound to lck-sh2 |
|
28
|
109
|
5mtjA |
Yes1-sh2 in complex with monobody mb(yes_1) |
|
27
|
108
|
5mtmA |
Monobody mb(lck_3) bound to lck-sh2 domain |
|
74
|
164
|
5m6uB |
Human pi3kdelta in complex with lasw1579 |
|
134
|
449
|
5mo4A |
Abl1 kinase (t334i_d382n) in complex with asciminib and nilotinib |
|
25
|
99
|
5jn0A |
Crk-ii sh2 domain |
|
85
|
266
|
5itdB |
Crystal structure of pi3k alpha with pi3k delta inhibitor |
|
153
|
522
|
5ibmA |
Structure of s502p, a cancer-associated mutation of the oncogenic phosphatase shp2 |
|
158
|
523
|
5i6vA |
Structure of f285s, a cancer-associated mutation of the oncogenic phosphatase shp2 |
|
128
|
447
|
5h0gA |
Crystal structure of hck complexed with a pyrrolo-pyrimidine inhibitor (s)-2-(((1r,4s)-4-(4-amino-5-(4-phenoxyphenyl)-7h-pyrrolo[2,3-d]pyrimidin-7-yl)cyclohexyl)amino)-n,4-dimethylpentanamide |
|
125
|
447
|
5h0eA |
Crystal structure of hck complexed with a pyrrolo-pyrimidine inhibitor (s)-2-(((1r,4s)-4-(4-amino-5-(4-phenoxyphenyl)-7h-pyrrolo[2,3-d]pyrimidin-7-yl)cyclohexyl)amino)-4-methylpentanamide |
|
89
|
265
|
4zopB |
Co-crystal structure of lipid kinase pi3k alpha with a selective phosphatidylinositol-3 kinase alpha inhibitor |
|
124
|
449
|
6f3fA |
Autoinhibited src kinase bound to adp |
|
135
|
481
|
6e2qA |
Structure of human jak2 ferm/sh2 in complex with erythropoietin receptor |
|
126
|
478
|
6e2pA |
Structure of human jak2 ferm/sh2 in complex with leptin receptor |
|
29
|
117
|
6c7yB |
Crystal structure of inhibitory protein socs1 in complex with jak1 kinase domain |
|
34
|
153
|
6c5xA |
Crystal structure of socs1 in complex with elonginb and elonginc |
|
158
|
523
|
6bmuA |
Non-receptor protein tyrosine phosphatase shp2 in complex with allosteric inhibitors shp099 and shp244 |
|
159
|
523
|
6bmyA |
Non-receptor protein tyrosine phosphatase shp2 in complex with allosteric inhibitors shp099 and shp844 |
|
140
|
516
|
6bn5A |
Non-receptor protein tyrosine phosphatase shp2 f285s in complex with allosteric inhibitor jlr-2 |
|
157
|
523
|
6bmxA |
Non-receptor protein tyrosine phosphatase shp2 in complex with allosteric inhibitor shp844 |
|
153
|
523
|
6bmvA |
Non-receptor protein tyrosine phosphatase shp2 in complex with allosteric inhibitor shp504 |
|
158
|
523
|
6bmrA |
Non-receptor protein tyrosine phosphatase shp2 in complex with allosteric inhibitor shp244 |
|
153
|
523
|
6bmwA |
Non-receptor protein tyrosine phosphatase shp2 in complex with allosteric inhibitors shp099 and shp504 |
|
58
|
255
|
6amvA |
Abl 1b regulatory module 'inhibiting state' |
|
145
|
524
|
6atdA |
Oxidized shp2 forms a disulfide bond between cys367 and cys459 |
|
48
|
255
|
6amwA |
Abl1b regulatory module 'activating' conformation |
|
48
|
216
|
5x94A |
Crystal structure of shp2_sh2-caga epiya_d peptide complex |
|
64
|
201
|
5vkoA |
Spt6 tsh2-rpb1 1468-1500 pt1471, ps1493 |
|
92
|
277
|
5xghB |
Crystal structure of pi3k complex with an inhibitor |
|
16
|
98
|
5cdwA |
Crystal structure analysis of a mutant grb2 sh2 domain (w121g) with a pyvnv peptide |
|
395
|
1347
|
4yknA |
Pi3k alpha lipid kinase with active site inhibitor |
|
40
|
168
|
5bo4A |
Structure of socs2:elongin c:elongin b from dmso-treated crystals |
|
124
|
478
|
4z32A |
Crystal structure of the ferm-sh2 domains of jak2 |
|
29
|
108
|
4f59A |
Triple mutant src sh2 domain |
|
28
|
108
|
4f5bA |
Triple mutant src sh2 domain bound to phosphotyrosine |
|
54
|
243
|
4ey0A |
Structure of tandem sh2 domains from plcgamma1 |
|
58
|
243
|
4fbnA |
Insights into structural integration of the plcgamma regulatory region and mechanism of autoinhibition and activation based on key roles of sh2 domains |
|
28
|
108
|
4f5aA |
Triple mutant src sh2 domain bound to phosphate ion |
|
107
|
377
|
4e93A |
Crystal structure of human feline sarcoma viral oncogene homologue (v-fes)in complex with tae684 |
|
24
|
101
|
4eihA |
Crystal structure of arg sh2 domain |
|
154
|
526
|
4dgpA |
The wild-type src homology 2 (sh2)-domain containing protein tyrosine phosphatase-2 (shp2) |
|
162
|
525
|
4dgxA |
Leopard syndrome-associated shp2/y279c mutant |
