1A41A

Type 1-topoisomerase catalytic fragment from vaccinia virus
Total Genus 72
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
72
sequence length
230
structure length
221
Chain Sequence
NAKRDRIFVRVYNVMKRINCFINKNIKKSSTDSNYQLAVFMLMETMFFKENETVGLLTLKNKHIEISPDEIVIKFVGKDKVSHEFVVHKSNRLYKPLLKLTDDSSPEEFLFNKLSERKVYECIKQFGIRIKDLRTYGVNYTFLYNFWTNVKSISPLPSPKKLIALTIKQTAEVVGHTPSISKRAYMATTILEMVKDKNFLDVVSKTTFDEFLSIVVDHVKS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Conservation of structure and mechanism between eukaryotic topoisomerase I and site-specific recombinases.
pubmed doi rcsb
molecule keywords TOPOISOMERASE I
molecule tags Isomerase
source organism Vaccinia virus
total genus 72
structure length 221
sequence length 230
ec nomenclature ec 5.99.1.2: Transferred entry: 5.6.2.2.
pdb deposition date 1998-02-10
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.120.380 Mainly Alpha Up-down Bundle Four Helix Bundle (Hemerythrin (Met), subunit A) Type 1-topoisomerase catalytic fragment, domain 2 1a41A02
3.90.15.10 Alpha Beta Alpha-Beta Complex Topoisomerase I; Chain A, domain 3 Topoisomerase I; Chain A, domain 3 1a41A01
1A31A 1K4TA 2H7GX 1RRJA 1SEUA 1NH3A 1T8IA 3IGCA 1A35A 1LPQA 1EJ9A 1R49A 1K4SA 2B9SA 3M4AA 1SC7A 1TL8A 2H7FX 1A36A 2F4QA 1A41A 1RR8C
chains in the Genus database with same CATH superfamily
2VCCA 3WG7C 3JRMO 3RIPA 2NSGA 1TWGA 2UUIA 2DB4A 4JCZA 3N0TA 1OW7A 2P61A 3ZG1A 3C62A 3W8IA 2NUTB 1BR4A 1MMAA 3ASNC 3K1IA 3LUTB 2OJQA 2R7RA 5L0JA 2CYDA 2AWYA 2PBEA 4IAOA 1J8MF 5DS5A 1J8YF 2A6EF 4N6HA 3PHF2 3H65A 4E0IA 1ZYRF 2DGJA 4BJ5A 4E7SA 3O55A 4CSAA 1GQAA 3GWLA 1G5ZA 3I5PA 4YT5A 3GWNA 3KH2A 2HV6A 3AOUA 3S28A 1WWPA 3H2VA 4I44A 3EPVA 3AG1C 1H9GA 1JR8A 2P6VA 4JE9A 1QSPA 3K1HA 1H9TA 3GEEA 4DVYP 1Z3IX 3G4XA 3ZDLA 3QVZA 1MQVA 2H7OA 2BE5F 1K4TA 4JC7A 3NYJA 3ZQYA 3GM3A 2PP4A 3IEEA 3I5QA 4LERA 1QLEC 1G8XA 1TR2A 1LVKA 2ETSA 2XM0A 3BEHA 3U8PA 4YL1A 5KYYA 5DLJA 3FVYA 4MVMA 3QMKA 3JYYA 2OG2A 3FAPB 3NKDA 1ZU5A 1ZW3A 1LS4A 4NY3A 4BPMA 3JCUQ 3S0XA 3C8GB 3I4UA 1LS1A 4ULVA 1TFOB 1FMWA 3L8IA 5L3VA 1NFNA 3GM1A 4G78A 3O6XA 4DRHB 1VK5A 4J30B 1ZHZA 4IJJA 3ABLC 4FWVA 1A41A 3DE8A 4JKVA 3TD7A 4AE4A 1D0XA 2PNOA 1NBBA 2J9WA 3ABKC 3EZIA 3JSEO 4HEAJ 5HSWA 3U3BA 3OA1A 2XS8A 2R7XA 4JURI 3C8ZA 3RF3A 1ZW2A 2VASA 4MNDA 3KYJA 2YZSA 1SMYF 2E87A 3AG4C 3QW1A 2XLOA 1CGOA 3TOLA 3V5YA 4Q4ZF 1JPJA 2EPMX 3RW0A 4XLPF 3Q6MA 5A6BA 4EHPA 2CNWD 1R49A 4JEBA 1K4SA 4LDQA 3TK0A 2GAQA 4G0HA 4K0DA 5GPGB 3F47A 3V5ZA 3JSZA 4FX5A 2WZGA 3JZ0A 3S29A 3RFYA 2Q4FA 3AQBA 3RH3A 3T9OA 2HZ8A 4JTDB 5A69A 4E18A 1YZAA 3DD7A 1OKKD 3IQ6A 1E2XA 3A11A 2L6FA 2OU6A 4O6YA 3E9VA 3R7CA 4E7ZA 2R7VA 3UGPA 4QI2A 1OW6A 4EKWA 2QY9A 4AL0A 2PFDA 1AEPA 1CGNA 2H8AA 2MWQA 1D1CA 3C18A 3HLZA 4J7TA 1ZVZA 3GANA 4XWJA 3S9OA 5AGFA 1XWJA 1HMOA 2XSEA 3AGUA 2HUJA 5L3QA 5IY5C 3MFNA 3VRCA 3QZCA 4WJ0A 4U5HA 2VCBA 1A35A 5TJ5E 2XM4A 2XL8A 3W8HA 3VF0A 3MYIA 2XS1A 3L0IA 5B1AC 3M4BA 1YYJA 2DYRC 4HE8D 5KYWA 1M6TA 1BZ4A 1K04A 3DJUB 4ZLCA 1TFKB 3IQ5A 4XEVA 4CDYA 2L6GA 1JOGA 2R25A 4A4AA 4KC9A 1E86A 1EI7A 1WGWA 2LSEA 4JTAB 1U0BB 5F28E 4LACB 5COFA 1K40A 3HKKA 3S84A 1A31A 1O3UA 2IOQA 3OWTA 2YQYA 1R5ID 3EG9B 1LIHA 1L3PA 1M56C 4XLNF 4DOZA 4NTFA 1U89A 2R7OA 4MVQA 2W45A 2OJED 2M4EA 4HFKB 4JTCB 4QI0A 5T1DB 5DS6A 4DRJB 5JVEA 3PDMP 4RDAA 1T8IA 2EIMC 2J9VA 3EHNA 3HNKA 2J46A 2OCCC 5BQGA 1EQ1A 3S90A 5HV9A 1LPQA 3NMJA 2EINC 3AG2C 5D92A 2EILC 4CS9A 1RJ9B 3AGTA 3JRTA 4H4KC 3SXZA 3ECSA 3FDQA 1A7VA 4DRIB 2YLIA 2L9JA 1C03A 1H7IA 2C04A 2P0NA 2UUHA 3K1IC 4KNWA 3SXKA 3WHNA 4K1OA 1MNDA 3EGDA 1Z63A 5JSLA 5DS4A 1LE2A 2EPLX 3FOOA 1ORSC 3NMKA 3BRJA 4IGGA 4MVOA 1LI7A 3CZ6A 2EPKX 2HSBA 3DXJF 3HJCA 2G3VA 2NUPA 3U5SA 5FZTA 1KTMA 1M2OA 2WZLA 4PACA 3U9MA 2Y3BA 3JYHA 4L6RA 3L8JA 3ZTZA 4CIHA 2H7GX 1DOWA 1VB5A 1Y4CA 2QE9A 2WZFA 1Z23A 3M79A 4H54A 2XLMA 4JZAA 1T01A 2RSEB 2YL3A 4CS8A 4KNVA 1AUEA 1ORYA 4LDRA 2H7BA 4YWQA 5B3IA 4OIOF 1ZU4A 4XEKA 2KJGA 1ZHTA 2R7WA 4NCQA 4B6IA 2BC5A 2IM8A 1WN0A 4WGYA 2XXAB 3M15A 5E33A 1TWHA 1AVOB 1O87A 4LLCA 3UGOA 5KYXA 5L0DA 5DQZA 4U5DE 3MLGA 1V4AA 3Q7GA 1SR2A 2HSQA 1A7DA 2IBFA 2Y3DA 3DM9B 1M57C 2ZXOA 3AG3C 3EZHA 4CX9A 1BR1A 2C03A 2YEVA 3X2QC 4A2NB 4C7OB 5L0FA 3TULA 1PV3A 4FESA 5A6BD 3ASOC 3V7OA 2PX0A 4MS2A 1HE9A 1Q0GA 2DI3A 4BEJA 3VAYA 4OD4A 2D5RB 3V5XA 4EUKB 2J8WA 5L0HA 1SZIA 2L7AA 4IRUA 1RKEA 1Q0FA 4LLEA 3POVA 2A0UA 4CJOA 1ZZPA 2IXNA 1Q0MA 2L6HA 2EIKC 1OXBA 2LK4A 2GFHA 4PFOA 1E85A 4G7OF 4CS7A 4BJ6A 4DBRA 3H2UA 1ZHYA 3ZIBA 5KYNA 2KNHA 1JPNA 4OIQF 3JTLO 1D1AA 1Q0DA 4OINF 3NKEA 2VH3A 4JJGA 2XLDA 1BR2A 3FOPA 1RKCA 1A7EA 3MX3A 1YARO 4CIPA 4OIPF 2ZD9A 2BL2A 1T6IA 4MW3A 5KYWB 4CJGA 1S7ZA 3MYFA 2OKUA 1G4WR 3SNHA 3DMDA 2KW3C 4P9FA 2HMQA 3EFOA 5F5FA 3LNRA 1YA9A 3GORA 3TQOA 5A6KA 2AWCA 4W8KA 2XL4A 2Y3HA 2H7VC 1OCRC 1HW2A 2YRFA 1SYQA 4AX2A 2ZXRA 1ORJA 3LS1A 4X0RA 3DI5A 1V54C 1FAPB 4EBJA 2NG1A 1U6HA 4BJ1A 5L0IA 4YT8A 3B71A 1I4YA 2Y39A 3EGXB 3ZQVA 1NLXA 2WB7A 5COGA 5AC5A 3QVYA 1TL8A 1W2WA 5KYUA 4NTAA 3EQLF 3SXYA 2V3CC 1MMGA 4U5EE 2R7SA 2Z15A 1D0ZA 1YVIA 3C63A 2Y69C 3TJ6A 4U9DA 1M2VB 2NUTA 2EIJC 1QQ3A 2XLVA 2LFFA 5D91A 1N1CA 2Y3GA 2W4MA 3Q6NA 4Q5SF 3IHUA 1I4ZA 3ITFA 4JCHA 1V55C 4U5FE 4G7ZF 2PF4E 4XPWA 4W8PA 1PD1A 2CDQA 4MVRA 2XL6A 2GA0A 1FTSA 4JEAA 4J32B 2R03A 3UMHA 2LD6A 3B9QA 4PJNA 1NFOA 2IXPA 5JT4A 1NZEA 4G7HF 1JAFA 3K66A 4YJWA 2H7FX 3ZTMA 1LI5A 3SZRA 1APCA 4R32A 3LEVA 1TQGA 4IB4A 1Y6DA 1K05A 4U5BE 3QW0A 3ZC4A 1Q0KA 3L1MA 2OEVA 4GQHA 4OD5A 1HE1A 2Q00A 2O9XA 2A68F 2A69F 4PJMA 4XPYA 2P7VA 4DJ9A 3T6GB 5KYXB 3TJ5A 1I5NA 1KNYA 3GODA 1LM3B 2KK1A 2KSFA 4ULWA 3RVYA 3ABMC 3U8VA 2YLGA 3C8GA 3DAFA 4E0HA 2OOCA 3UR3C 1OCZC 4C3EA 4YL0A 1HY5A 2YVKA 3IGCA 2J0XA 2Q9AA 1YDIA 1D0YA 2G3KA 2HJ3A 2W4BA 4OIRF 1FFHA 1Z6AA 4ONSA 2W9YA 3DKAA 3U2LA 2YL0A 2I8BA 1RMVA 1VLTA 3OEOA 1A36A 4WABA 5KYYB 2OEXA 2ZPAA 5BUOA 1QVXA 2DYSC 1WASA 1OR2A 2KGOA 1VOMA 2XRHA 1Z5ZA 3NYLA 2R7UA 3FXHA 4AL1A 1YZCA 1QPUA 4YK5A 3U0CA 2TMVP 4N06A 2R05A 3NG1A 4EBBA 2HV7A 4BJ5C 4CDAA 4CSAC 1TWCA 5BQIA 4KI2A 1OKKA 2IXMA 2M64A 3LESA 4JRZA 3B0UX 2WL8A 1RCPA 2YL1A 1B68A 1SF8A 2AVKA 3B29A 4JIOA 4O7GA 2YHSA 4AE4B 2VC9A 1WATA 3E70C 3O10A 3UMIA 2X51A 4CBEA 4NQFA 1ZHWA 1KU2A 2FGYA 4P9TA 3RVZA 3US6A 4EIYA 1VLSA 3DJNB 2HS5A 1G4US 2F22A 3GEIA 1OQCA 4MTFA 2X0CA 1H6GA 4EBKA 2HKVA 4DXWA 1MMDA 1ST6A 3AQCA 1Z7Qc 5L0GA 3J06A 1OCOC 3RKOF 3SXMA 1E83A 4MTGA 1VYKA 2LIGA 4D4XA 4EWCA 2Q3TA 1VMAA 1IW7F 2VB6A 4GYTA 5T3TA 4BJ6C 1VYIA 5JUAA 3G50A 3U3FA 2Q7RA 3N24A 2J7PA 3NYMA 4IAQA 4O79A 2A0BA 2ASRA 3N2ZB 1OR3A 1D1BA 1XZPA 2EPNA 2WVOA 1V74B 1SEUA 2AU5A 3CAXA 1OXKA 3LLKA 4ER9A 3SP1A 4UDVA 1UG7A 3DM5A 1CPRA 3LS0A 4XQ1A 2LQGA 2R9RB 2A6HF 2JPUA 2A1DD 3O39A 4YL3A 5DQTA 5A6AA 3RYLA 3RQFA 3HNJA 2NSFA 3EG9A 3IPMO 1NH3A 4PR9A 4NC3A 5CI8A 1FMVA 5JRAA 1NU7D 2G62A 3ATPA 3GEHA 1HW1A 3M4CA 3Q7LA 1OW8A 3QTHA 5AC4A 1YJGA 5JP7A 4MTOA 2P1AA 3EH1A 5A6JA 5K0IA 1T9KA 2WVNA 2R02A 2D4UA 4MVSA 4O6MA 1RJ9A 2QUPA 2FFHA 2CW0F 2R7QA 2XLWA 4HFFB 4O6NA 1EKYA 256BA 3CQZA 5CI9A 1E84A 2OQMA 3R2PA 4QDLA 4IWBA 3IQTA 2XLEA 2NPUA 1JRAA 1NG1A 3SEOA 3LEOA 2JD3A 5B3SC 4P6IC 5T3WA 3PMRA 2MHRA 3FHDA 2B0JA 3HNIA 4DVZA 1F1MA 2JX0A 4XEFA 2J9BA 4ZLDA 3U2MA 1YA7O 2KC3A 4LDKA 2LFDA 4MVUA 2PX3A 5BQHA 3VM6A 1S05A 1WOLA 2KYHA 2QNLA 1OCCC 2WVQA 4PK4A 3A9CA 3C8GD 1MNEA 3KMIA 4U5CE 4Z9HA 3EHMA 5FCLA 1FNTc 1TKNA 4Q7CA 4U5GA 2QLAA 1ZHXA 2YKZA 3ZSUA 4BJTA 3LAYA 4F4BA 3CSKA 1VTMP 3EGDB 3HNLA 3LJBA 1XZQA 4U9EA 4BG0A 3UMKA 3W2VA 3PCVA 3HTKC 2HMZA 3LNMB 3VYWA 2XXAA 1YLMA 2CGEA 4XPXA 2NUPB 1EJ9A 3M1CB 1O5HA 2HJMA 2LCHA 3KL4A 4YT2A 5EK0A 3WODF 3F46A 3X1OA 4BEMJ 2AP3A 4M63A 3T6JA 3ZVRA 2L81A 5COMA 2ZXWC 3K33A 3SYNA 4C7OA 4Z9JA 2F4QA 4I1MA 3ZWIA 1NSGB 4PFPA 1T6QA 3U9JA 5L0CA 1LPEA 2KQ9A 2VCAA 3EH2A 4FAPB 4YN0B 4CS9C 3DZAA 5DVWA 4IARA 1RR8C 3GM2A 2ZXPA 1BBHA 1UFBA 4PJJA 5E3CA 1TWAA 5JLIA 1T5OA 1RRJA 2IXOA 4N4WA 1C17M 4RD9A 3TOMA 2YWAA 4KBLA 1GGQA 1HMDA 3W2WA 2I15A 1IZMA 3DE9A 4N6CA 5E3AA 4E17A 1GM5A 4AK9A 1T6UA 4NTBA 2MYSA 1YAUO 5CIVA 2R7TA 2B9SA 4Z9IA 2CCYA 3FMSA 3LLIA 3NMIA 1SC7A 1MMNA 1RKEB 1R4TA 1CPQA 2GWWA 1L7CA 3KKBA 4RBNA 2HFIA 3K6BA 2J7PD 4I3MA 4PJLA 5B1BC 3UNGC 4C3BA 4CS8C 2CNWA 3NDBB 1FFTC 3B0PA 2B0HA 4DBQA 5JS5A 4D4NA 1RXQA 4ANJA 5EGYA 1WTYA 5EHHA 3RQEA 2FAPB 5F5HA 4JW1A 1QKRA 4JJFA 1A0BA 2J45A 2J0WA 2Q9CA 1LKXA 4K7BA 4WGZA 2EPOA 2YL7A 3EGXA 3FAJA 4XTKA 3L34A 4GEHA 2ICWG 3K7DA 1YYXA 2J9UA 1NU9C 1PD0A 1PCXA 4C3DA 1DOVA 1BDJB 3WAQA 3W4YA 3C7JA 2XLHA 2V26A 3AJMA 3EFOB 3T4RA 4MVZA 5E2QA 4YT4A 2Q9BA 3IQCA 3MBGA 2RD9A 3KYIA 1QZXA 3M4AA 1M2VA 3CEXA 3G4ZA 4MW8A 3NRHA 4I1OB 2YLDA 3T6BA 1GS9A 3B0VC 3JT1A 1EA8A 3EJNA 1LE4A 1C02A 3RQGA 2QTVA 1CGME 3S27A 4JVSA 1FR0A 3KPHA 2LP4A 3DAGA 2GDCA 4J7YA 4CDVA 3DWWA 1JMWA 2IYLD 5KYUB 4MQ9F
chains in the Genus database with same CATH topology
1A31A 1K4TA 2H7GX 1RRJA 1SEUA 1NH3A 1T8IA 3IGCA 1A35A 1LPQA 1EJ9A 1R49A 1K4SA 2B9SA 3M4AA 1SC7A 1TL8A 2H7FX 1A36A 2F4QA 1A41A 1RR8C
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1A31 A;  1K4T A;  2H7G X;  1RRJ A;  1SEU A;  1NH3 A;  1T8I A;  3IGC A;  1A35 A;  1LPQ A;  1EJ9 A;  1R49 A;  1K4S A;  2B9S A;  3M4A A;  1SC7 A;  1TL8 A;  2H7F X;  1A36 A;  2F4Q A;  1A41 A;  1RR8 C; 
#chains in the Genus database with same CATH topology
 2VCC A;  3WG7 C;  3JRM O;  3RIP A;  2NSG A;  1TWG A;  2UUI A;  2DB4 A;  4JCZ A;  3N0T A;  1OW7 A;  2P61 A;  3ZG1 A;  3C62 A;  3W8I A;  2NUT B;  1BR4 A;  1MMA A;  3ASN C;  3K1I A;  3LUT B;  2OJQ A;  2R7R A;  5L0J A;  2CYD A;  2AWY A;  2PBE A;  4IAO A;  1J8M F;  5DS5 A;  1J8Y F;  2A6E F;  4N6H A;  3PHF 2;  3H65 A;  4E0I A;  1ZYR F;  2DGJ A;  4BJ5 A;  4E7S A;  3O55 A;  4CSA A;  1GQA A;  3GWL A;  1G5Z A;  3I5P A;  4YT5 A;  3GWN A;  3KH2 A;  2HV6 A;  3AOU A;  3S28 A;  1WWP A;  3H2V A;  4I44 A;  3EPV A;  3AG1 C;  1H9G A;  1JR8 A;  2P6V A;  4JE9 A;  1QSP A;  3K1H A;  1H9T A;  3GEE A;  4DVY P;  1Z3I X;  3G4X A;  3ZDL A;  3QVZ A;  1MQV A;  2H7O A;  2BE5 F;  1K4T A;  4JC7 A;  3NYJ A;  3ZQY A;  3GM3 A;  2PP4 A;  3IEE A;  3I5Q A;  4LER A;  1QLE C;  1G8X A;  1TR2 A;  1LVK A;  2ETS A;  2XM0 A;  3BEH A;  3U8P A;  4YL1 A;  5KYY A;  5DLJ A;  3FVY A;  4MVM A;  3QMK A;  3JYY A;  2OG2 A;  3FAP B;  3NKD A;  1ZU5 A;  1ZW3 A;  1LS4 A;  4NY3 A;  4BPM A;  3JCU Q;  3S0X A;  3C8G B;  3I4U A;  1LS1 A;  4ULV A;  1TFO B;  1FMW A;  3L8I A;  5L3V A;  1NFN A;  3GM1 A;  4G78 A;  3O6X A;  4DRH B;  1VK5 A;  4J30 B;  1ZHZ A;  4IJJ A;  3ABL C;  4FWV A;  1A41 A;  3DE8 A;  4JKV A;  3TD7 A;  4AE4 A;  1D0X A;  2PNO A;  1NBB A;  2J9W A;  3ABK C;  3EZI A;  3JSE O;  4HEA J;  5HSW A;  3U3B A;  3OA1 A;  2XS8 A;  2R7X A;  4JUR I;  3C8Z A;  3RF3 A;  1ZW2 A;  2VAS A;  4MND A;  3KYJ A;  2YZS A;  1SMY F;  2E87 A;  3AG4 C;  3QW1 A;  2XLO A;  1CGO A;  3TOL A;  3V5Y A;  4Q4Z F;  1JPJ A;  2EPM X;  3RW0 A;  4XLP F;  3Q6M A;  5A6B A;  4EHP A;  2CNW D;  1R49 A;  4JEB A;  1K4S A;  4LDQ A;  3TK0 A;  2GAQ A;  4G0H A;  4K0D A;  5GPG B;  3F47 A;  3V5Z A;  3JSZ A;  4FX5 A;  2WZG A;  3JZ0 A;  3S29 A;  3RFY A;  2Q4F A;  3AQB A;  3RH3 A;  3T9O A;  2HZ8 A;  4JTD B;  5A69 A;  4E18 A;  1YZA A;  3DD7 A;  1OKK D;  3IQ6 A;  1E2X A;  3A11 A;  2L6F A;  2OU6 A;  4O6Y A;  3E9V A;  3R7C A;  4E7Z A;  2R7V A;  3UGP A;  4QI2 A;  1OW6 A;  4EKW A;  2QY9 A;  4AL0 A;  2PFD A;  1AEP A;  1CGN A;  2H8A A;  2MWQ A;  1D1C A;  3C18 A;  3HLZ A;  4J7T A;  1ZVZ A;  3GAN A;  4XWJ A;  3S9O A;  5AGF A;  1XWJ A;  1HMO A;  2XSE A;  3AGU A;  2HUJ A;  5L3Q A;  5IY5 C;  3MFN A;  3VRC A;  3QZC A;  4WJ0 A;  4U5H A;  2VCB A;  1A35 A;  5TJ5 E;  2XM4 A;  2XL8 A;  3W8H A;  3VF0 A;  3MYI A;  2XS1 A;  3L0I A;  5B1A C;  3M4B A;  1YYJ A;  2DYR C;  4HE8 D;  5KYW A;  1M6T A;  1BZ4 A;  1K04 A;  3DJU B;  4ZLC A;  1TFK B;  3IQ5 A;  4XEV A;  4CDY A;  2L6G A;  1JOG A;  2R25 A;  4A4A A;  4KC9 A;  1E86 A;  1EI7 A;  1WGW A;  2LSE A;  4JTA B;  1U0B B;  5F28 E;  4LAC B;  5COF A;  1K40 A;  3HKK A;  3S84 A;  1A31 A;  1O3U A;  2IOQ A;  3OWT A;  2YQY A;  1R5I D;  3EG9 B;  1LIH A;  1L3P A;  1M56 C;  4XLN F;  4DOZ A;  4NTF A;  1U89 A;  2R7O A;  4MVQ A;  2W45 A;  2OJE D;  2M4E A;  4HFK B;  4JTC B;  4QI0 A;  5T1D B;  5DS6 A;  4DRJ B;  5JVE A;  3PDM P;  4RDA A;  1T8I A;  2EIM C;  2J9V A;  3EHN A;  3HNK A;  2J46 A;  2OCC C;  5BQG A;  1EQ1 A;  3S90 A;  5HV9 A;  1LPQ A;  3NMJ A;  2EIN C;  3AG2 C;  5D92 A;  2EIL C;  4CS9 A;  1RJ9 B;  3AGT A;  3JRT A;  4H4K C;  3SXZ A;  3ECS A;  3FDQ A;  1A7V A;  4DRI B;  2YLI A;  2L9J A;  1C03 A;  1H7I A;  2C04 A;  2P0N A;  2UUH A;  3K1I C;  4KNW A;  3SXK A;  3WHN A;  4K1O A;  1MND A;  3EGD A;  1Z63 A;  5JSL A;  5DS4 A;  1LE2 A;  2EPL X;  3FOO A;  1ORS C;  3NMK A;  3BRJ A;  4IGG A;  4MVO A;  1LI7 A;  3CZ6 A;  2EPK X;  2HSB A;  3DXJ F;  3HJC A;  2G3V A;  2NUP A;  3U5S A;  5FZT A;  1KTM A;  1M2O A;  2WZL A;  4PAC A;  3U9M A;  2Y3B A;  3JYH A;  4L6R A;  3L8J A;  3ZTZ A;  4CIH A;  2H7G X;  1DOW A;  1VB5 A;  1Y4C A;  2QE9 A;  2WZF A;  1Z23 A;  3M79 A;  4H54 A;  2XLM A;  4JZA A;  1T01 A;  2RSE B;  2YL3 A;  4CS8 A;  4KNV A;  1AUE A;  1ORY A;  4LDR A;  2H7B A;  4YWQ A;  5B3I A;  4OIO F;  1ZU4 A;  4XEK A;  2KJG A;  1ZHT A;  2R7W A;  4NCQ A;  4B6I A;  2BC5 A;  2IM8 A;  1WN0 A;  4WGY A;  2XXA B;  3M15 A;  5E33 A;  1TWH A;  1AVO B;  1O87 A;  4LLC A;  3UGO A;  5KYX A;  5L0D A;  5DQZ A;  4U5D E;  3MLG A;  1V4A A;  3Q7G A;  1SR2 A;  2HSQ A;  1A7D A;  2IBF A;  2Y3D A;  3DM9 B;  1M57 C;  2ZXO A;  3AG3 C;  3EZH A;  4CX9 A;  1BR1 A;  2C03 A;  2YEV A;  3X2Q C;  4A2N B;  4C7O B;  5L0F A;  3TUL A;  1PV3 A;  4FES A;  5A6B D;  3ASO C;  3V7O A;  2PX0 A;  4MS2 A;  1HE9 A;  1Q0G A;  2DI3 A;  4BEJ A;  3VAY A;  4OD4 A;  2D5R B;  3V5X A;  4EUK B;  2J8W A;  5L0H A;  1SZI A;  2L7A A;  4IRU A;  1RKE A;  1Q0F A;  4LLE A;  3POV A;  2A0U A;  4CJO A;  1ZZP A;  2IXN A;  1Q0M A;  2L6H A;  2EIK C;  1OXB A;  2LK4 A;  2GFH A;  4PFO A;  1E85 A;  4G7O F;  4CS7 A;  4BJ6 A;  4DBR A;  3H2U A;  1ZHY A;  3ZIB A;  5KYN A;  2KNH A;  1JPN A;  4OIQ F;  3JTL O;  1D1A A;  1Q0D A;  4OIN F;  3NKE A;  2VH3 A;  4JJG A;  2XLD A;  1BR2 A;  3FOP A;  1RKC A;  1A7E A;  3MX3 A;  1YAR O;  4CIP A;  4OIP F;  2ZD9 A;  2BL2 A;  1T6I A;  4MW3 A;  5KYW B;  4CJG A;  1S7Z A;  3MYF A;  2OKU A;  1G4W R;  3SNH A;  3DMD A;  2KW3 C;  4P9F A;  2HMQ A;  3EFO A;  5F5F A;  3LNR A;  1YA9 A;  3GOR A;  3TQO A;  5A6K A;  2AWC A;  4W8K A;  2XL4 A;  2Y3H A;  2H7V C;  1OCR C;  1HW2 A;  2YRF A;  1SYQ A;  4AX2 A;  2ZXR A;  1ORJ A;  3LS1 A;  4X0R A;  3DI5 A;  1V54 C;  1FAP B;  4EBJ A;  2NG1 A;  1U6H A;  4BJ1 A;  5L0I A;  4YT8 A;  3B71 A;  1I4Y A;  2Y39 A;  3EGX B;  3ZQV A;  1NLX A;  2WB7 A;  5COG A;  5AC5 A;  3QVY A;  1TL8 A;  1W2W A;  5KYU A;  4NTA A;  3EQL F;  3SXY A;  2V3C C;  1MMG A;  4U5E E;  2R7S A;  2Z15 A;  1D0Z A;  1YVI A;  3C63 A;  2Y69 C;  3TJ6 A;  4U9D A;  1M2V B;  2NUT A;  2EIJ C;  1QQ3 A;  2XLV A;  2LFF A;  5D91 A;  1N1C A;  2Y3G A;  2W4M A;  3Q6N A;  4Q5S F;  3IHU A;  1I4Z A;  3ITF A;  4JCH A;  1V55 C;  4U5F E;  4G7Z F;  2PF4 E;  4XPW A;  4W8P A;  1PD1 A;  2CDQ A;  4MVR A;  2XL6 A;  2GA0 A;  1FTS A;  4JEA A;  4J32 B;  2R03 A;  3UMH A;  2LD6 A;  3B9Q A;  4PJN A;  1NFO A;  2IXP A;  5JT4 A;  1NZE A;  4G7H F;  1JAF A;  3K66 A;  4YJW A;  2H7F X;  3ZTM A;  1LI5 A;  3SZR A;  1APC A;  4R32 A;  3LEV A;  1TQG A;  4IB4 A;  1Y6D A;  1K05 A;  4U5B E;  3QW0 A;  3ZC4 A;  1Q0K A;  3L1M A;  2OEV A;  4GQH A;  4OD5 A;  1HE1 A;  2Q00 A;  2O9X A;  2A68 F;  2A69 F;  4PJM A;  4XPY A;  2P7V A;  4DJ9 A;  3T6G B;  5KYX B;  3TJ5 A;  1I5N A;  1KNY A;  3GOD A;  1LM3 B;  2KK1 A;  2KSF A;  4ULW A;  3RVY A;  3ABM C;  3U8V A;  2YLG A;  3C8G A;  3DAF A;  4E0H A;  2OOC A;  3UR3 C;  1OCZ C;  4C3E A;  4YL0 A;  1HY5 A;  2YVK A;  3IGC A;  2J0X A;  2Q9A A;  1YDI A;  1D0Y A;  2G3K A;  2HJ3 A;  2W4B A;  4OIR F;  1FFH A;  1Z6A A;  4ONS A;  2W9Y A;  3DKA A;  3U2L A;  2YL0 A;  2I8B A;  1RMV A;  1VLT A;  3OEO A;  1A36 A;  4WAB A;  5KYY B;  2OEX A;  2ZPA A;  5BUO A;  1QVX A;  2DYS C;  1WAS A;  1OR2 A;  2KGO A;  1VOM A;  2XRH A;  1Z5Z A;  3NYL A;  2R7U A;  3FXH A;  4AL1 A;  1YZC A;  1QPU A;  4YK5 A;  3U0C A;  2TMV P;  4N06 A;  2R05 A;  3NG1 A;  4EBB A;  2HV7 A;  4BJ5 C;  4CDA A;  4CSA C;  1TWC A;  5BQI A;  4KI2 A;  1OKK A;  2IXM A;  2M64 A;  3LES A;  4JRZ A;  3B0U X;  2WL8 A;  1RCP A;  2YL1 A;  1B68 A;  1SF8 A;  2AVK A;  3B29 A;  4JIO A;  4O7G A;  2YHS A;  4AE4 B;  2VC9 A;  1WAT A;  3E70 C;  3O10 A;  3UMI A;  2X51 A;  4CBE A;  4NQF A;  1ZHW A;  1KU2 A;  2FGY A;  4P9T A;  3RVZ A;  3US6 A;  4EIY A;  1VLS A;  3DJN B;  2HS5 A;  1G4U S;  2F22 A;  3GEI A;  1OQC A;  4MTF A;  2X0C A;  1H6G A;  4EBK A;  2HKV A;  4DXW A;  1MMD A;  1ST6 A;  3AQC A;  1Z7Q c;  5L0G A;  3J06 A;  1OCO C;  3RKO F;  3SXM A;  1E83 A;  4MTG A;  1VYK A;  2LIG A;  4D4X A;  4EWC A;  2Q3T A;  1VMA A;  1IW7 F;  2VB6 A;  4GYT A;  5T3T A;  4BJ6 C;  1VYI A;  5JUA A;  3G50 A;  3U3F A;  2Q7R A;  3N24 A;  2J7P A;  3NYM A;  4IAQ A;  4O79 A;  2A0B A;  2ASR A;  3N2Z B;  1OR3 A;  1D1B A;  1XZP A;  2EPN A;  2WVO A;  1V74 B;  1SEU A;  2AU5 A;  3CAX A;  1OXK A;  3LLK A;  4ER9 A;  3SP1 A;  4UDV A;  1UG7 A;  3DM5 A;  1CPR A;  3LS0 A;  4XQ1 A;  2LQG A;  2R9R B;  2A6H F;  2JPU A;  2A1D D;  3O39 A;  4YL3 A;  5DQT A;  5A6A A;  3RYL A;  3RQF A;  3HNJ A;  2NSF A;  3EG9 A;  3IPM O;  1NH3 A;  4PR9 A;  4NC3 A;  5CI8 A;  1FMV A;  5JRA A;  1NU7 D;  2G62 A;  3ATP A;  3GEH A;  1HW1 A;  3M4C A;  3Q7L A;  1OW8 A;  3QTH A;  5AC4 A;  1YJG A;  5JP7 A;  4MTO A;  2P1A A;  3EH1 A;  5A6J A;  5K0I A;  1T9K A;  2WVN A;  2R02 A;  2D4U A;  4MVS A;  4O6M A;  1RJ9 A;  2QUP A;  2FFH A;  2CW0 F;  2R7Q A;  2XLW A;  4HFF B;  4O6N A;  1EKY A;  256B A;  3CQZ A;  5CI9 A;  1E84 A;  2OQM A;  3R2P A;  4QDL A;  4IWB A;  3IQT A;  2XLE A;  2NPU A;  1JRA A;  1NG1 A;  3SEO A;  3LEO A;  2JD3 A;  5B3S C;  4P6I C;  5T3W A;  3PMR A;  2MHR A;  3FHD A;  2B0J A;  3HNI A;  4DVZ A;  1F1M A;  2JX0 A;  4XEF A;  2J9B A;  4ZLD A;  3U2M A;  1YA7 O;  2KC3 A;  4LDK A;  2LFD A;  4MVU A;  2PX3 A;  5BQH A;  3VM6 A;  1S05 A;  1WOL A;  2KYH A;  2QNL A;  1OCC C;  2WVQ A;  4PK4 A;  3A9C A;  3C8G D;  1MNE A;  3KMI A;  4U5C E;  4Z9H A;  3EHM A;  5FCL A;  1FNT c;  1TKN A;  4Q7C A;  4U5G A;  2QLA A;  1ZHX A;  2YKZ A;  3ZSU A;  4BJT A;  3LAY A;  4F4B A;  3CSK A;  1VTM P;  3EGD B;  3HNL A;  3LJB A;  1XZQ A;  4U9E A;  4BG0 A;  3UMK A;  3W2V A;  3PCV A;  3HTK C;  2HMZ A;  3LNM B;  3VYW A;  2XXA A;  1YLM A;  2CGE A;  4XPX A;  2NUP B;  1EJ9 A;  3M1C B;  1O5H A;  2HJM A;  2LCH A;  3KL4 A;  4YT2 A;  5EK0 A;  3WOD F;  3F46 A;  3X1O A;  4BEM J;  2AP3 A;  4M63 A;  3T6J A;  3ZVR A;  2L81 A;  5COM A;  2ZXW C;  3K33 A;  3SYN A;  4C7O A;  4Z9J A;  2F4Q A;  4I1M A;  3ZWI A;  1NSG B;  4PFP A;  1T6Q A;  3U9J A;  5L0C A;  1LPE A;  2KQ9 A;  2VCA A;  3EH2 A;  4FAP B;  4YN0 B;  4CS9 C;  3DZA A;  5DVW A;  4IAR A;  1RR8 C;  3GM2 A;  2ZXP A;  1BBH A;  1UFB A;  4PJJ A;  5E3C A;  1TWA A;  5JLI A;  1T5O A;  1RRJ A;  2IXO A;  4N4W A;  1C17 M;  4RD9 A;  3TOM A;  2YWA A;  4KBL A;  1GGQ A;  1HMD A;  3W2W A;  2I15 A;  1IZM A;  3DE9 A;  4N6C A;  5E3A A;  4E17 A;  1GM5 A;  4AK9 A;  1T6U A;  4NTB A;  2MYS A;  1YAU O;  5CIV A;  2R7T A;  2B9S A;  4Z9I A;  2CCY A;  3FMS A;  3LLI A;  3NMI A;  1SC7 A;  1MMN A;  1RKE B;  1R4T A;  1CPQ A;  2GWW A;  1L7C A;  3KKB A;  4RBN A;  2HFI A;  3K6B A;  2J7P D;  4I3M A;  4PJL A;  5B1B C;  3UNG C;  4C3B A;  4CS8 C;  2CNW A;  3NDB B;  1FFT C;  3B0P A;  2B0H A;  4DBQ A;  5JS5 A;  4D4N A;  1RXQ A;  4ANJ A;  5EGY A;  1WTY A;  5EHH A;  3RQE A;  2FAP B;  5F5H A;  4JW1 A;  1QKR A;  4JJF A;  1A0B A;  2J45 A;  2J0W A;  2Q9C A;  1LKX A;  4K7B A;  4WGZ A;  2EPO A;  2YL7 A;  3EGX A;  3FAJ A;  4XTK A;  3L34 A;  4GEH A;  2ICW G;  3K7D A;  1YYX A;  2J9U A;  1NU9 C;  1PD0 A;  1PCX A;  4C3D A;  1DOV A;  1BDJ B;  3WAQ A;  3W4Y A;  3C7J A;  2XLH A;  2V26 A;  3AJM A;  3EFO B;  3T4R A;  4MVZ A;  5E2Q A;  4YT4 A;  2Q9B A;  3IQC A;  3MBG A;  2RD9 A;  3KYI A;  1QZX A;  3M4A A;  1M2V A;  3CEX A;  3G4Z A;  4MW8 A;  3NRH A;  4I1O B;  2YLD A;  3T6B A;  1GS9 A;  3B0V C;  3JT1 A;  1EA8 A;  3EJN A;  1LE4 A;  1C02 A;  3RQG A;  2QTV A;  1CGM E;  3S27 A;  4JVS A;  1FR0 A;  3KPH A;  2LP4 A;  3DAG A;  2GDC A;  4J7Y A;  4CDV A;  3DWW A;  1JMW A;  2IYL D;  5KYU B;  4MQ9 F; 
#chains in the Genus database with same CATH homology
 1A31 A;  1K4T A;  2H7G X;  1RRJ A;  1SEU A;  1NH3 A;  1T8I A;  3IGC A;  1A35 A;  1LPQ A;  1EJ9 A;  1R49 A;  1K4S A;  2B9S A;  3M4A A;  1SC7 A;  1TL8 A;  2H7F X;  1A36 A;  2F4Q A;  1A41 A;  1RR8 C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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