1A59A

Cold-active citrate synthase
Total Genus 133
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
133
sequence length
377
structure length
377
Chain Sequence
EPTIHKGLAGVTADVTAISKVNSDTNSLLYRGYPVQELAAKCSFEQVAYLLWNSELPNDSELKAFVNFERSHRKLDENVKGAIDLLSTACHPMDVARTAVSVLGANHARAQDSSPEANLEKAMSLLATFPSVVAYDQRRRRGEELIEPREDLDYSANFLWMTFGEEAAPEVVEAFNVSMILYAEHSFNASTFTARVITSTLADLHSAVTGAIGALKGPLHGGANEAVMHTFEEIGIRKDESLDEAATRSKAWMVDALAQKKKVMGFGHRVYKNGDSRVPTMKSALDAMIKHYDRPEMLGLYNGLEAAMEEAKQIKPNLDYPAGPTYNLMGFDTEMFTPLFIAARITGWTAHIMEQVADNALIRPLSEYNGPEQRQVP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural adaptations of the cold-active citrate synthase from an Antarctic bacterium.
pubmed doi rcsb
molecule tags Cold-activity
source organism Antarctic bacterium ds2-3r
molecule keywords CITRATE SYNTHASE
total genus 133
structure length 377
sequence length 377
ec nomenclature ec 2.3.3.16: Citrate synthase (unknown stereospecificity).
pdb deposition date 1998-02-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00285 Citrate_synt Citrate synthase, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.230.10 Mainly Alpha Orthogonal Bundle Cytochrome p450-Terp; domain 2 Cytochrome P450-Terp, domain 2 1a59A02
1.10.580.10 Mainly Alpha Orthogonal Bundle Citrate Synthase; domain 1 Citrate Synthase, domain 1 1a59A01
1CSHA 3HWKA 2C6XA 4YBOA 4E6YA 4XGHA 2CSCA 4JADA 1CSCA 3MSUA 3TQGA 4CTSA 1OWCA 1CSSA 1O7XA 3O8JA 5CTSA 1AL6A 2CTSA 1AMZA 1NXGA 1VGMA 1AJ8A 3CSCA 4JAEA 2P2WA 4CSCA 3ENJA 6CSCA 1OWBA 2R26A 4G6BA 2R9EA 2IFCA 1IOMA 2IBPA 1NXEA 4JAFA 4TVMA 6CTSA 1A59A 1CSRA 1CSIA 2H12A 1CTSA 1IXEA 5CSCA 4JAGA 5CSCB 1VGPA
chains in the Genus database with same CATH superfamily
1CSHA 3HWKA 2C6XA 4YBOA 4XGHA 4E6YA 2CSCA 4JADA 1CSCA 3MSUA 3TQGA 4CTSA 1OWCA 1CSSA 1O7XA 3O8JA 5CTSA 1AL6A 2CTSA 1AMZA 1NXGA 1VGMA 1AJ8A 3CSCA 4JAEA 2P2WA 4CSCA 3ENJA 6CSCA 1OWBA 2R26A 4G6BA 2R9EA 2IFCA 1IOMA 2IBPA 1NXEA 4JAFA 4TVMA 6CTSA 1A59A 1CSRA 1CSIA 2H12A 1CTSA 1IXEA 5CSCA 4JAGA 5CSCB 1VGPA
chains in the Genus database with same CATH topology
1CSHA 3HWKA 2C6XA 4YBOA 4E6YA 4XGHA 2CSCA 4JADA 1CSCA 3MSUA 3TQGA 4CTSA 1OWCA 1CSSA 1O7XA 3O8JA 5CTSA 1AL6A 2CTSA 1AMZA 1NXGA 1VGMA 1AJ8A 3CSCA 4JAEA 2P2WA 4CSCA 3ENJA 6CSCA 1OWBA 2R26A 4G6BA 2R9EA 2IFCA 1IOMA 2IBPA 1NXEA 4JAFA 4TVMA 6CTSA 1A59A 1CSRA 1CSIA 2H12A 1CTSA 1IXEA 5CSCA 4JAGA 5CSCB 1VGPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1CSH A;  3HWK A;  2C6X A;  4YBO A;  4E6Y A;  4XGH A;  2CSC A;  4JAD A;  1CSC A;  3MSU A;  3TQG A;  4CTS A;  1OWC A;  1CSS A;  1O7X A;  3O8J A;  5CTS A;  1AL6 A;  2CTS A;  1AMZ A;  1NXG A;  1VGM A;  1AJ8 A;  3CSC A;  4JAE A;  2P2W A;  4CSC A;  3ENJ A;  6CSC A;  1OWB A;  2R26 A;  4G6B A;  2R9E A;  2IFC A;  1IOM A;  2IBP A;  1NXE A;  4JAF A;  4TVM A;  6CTS A;  1A59 A;  1CSR A;  1CSI A;  2H12 A;  1CTS A;  1IXE A;  5CSC A;  4JAG A;  5CSC B;  1VGP A; 
#chains in the Genus database with same CATH topology
 1CSH A;  3HWK A;  2C6X A;  4YBO A;  4XGH A;  4E6Y A;  2CSC A;  4JAD A;  1CSC A;  3MSU A;  3TQG A;  4CTS A;  1OWC A;  1CSS A;  1O7X A;  3O8J A;  5CTS A;  1AL6 A;  2CTS A;  1AMZ A;  1NXG A;  1VGM A;  1AJ8 A;  3CSC A;  4JAE A;  2P2W A;  4CSC A;  3ENJ A;  6CSC A;  1OWB A;  2R26 A;  4G6B A;  2R9E A;  2IFC A;  1IOM A;  2IBP A;  1NXE A;  4JAF A;  4TVM A;  6CTS A;  1A59 A;  1CSR A;  1CSI A;  2H12 A;  1CTS A;  1IXE A;  5CSC A;  4JAG A;  5CSC B;  1VGP A; 
#chains in the Genus database with same CATH homology
 1CSH A;  3HWK A;  2C6X A;  4YBO A;  4E6Y A;  4XGH A;  2CSC A;  4JAD A;  1CSC A;  3MSU A;  3TQG A;  4CTS A;  1OWC A;  1CSS A;  1O7X A;  3O8J A;  5CTS A;  1AL6 A;  2CTS A;  1AMZ A;  1NXG A;  1VGM A;  1AJ8 A;  3CSC A;  4JAE A;  2P2W A;  4CSC A;  3ENJ A;  6CSC A;  1OWB A;  2R26 A;  4G6B A;  2R9E A;  2IFC A;  1IOM A;  2IBP A;  1NXE A;  4JAF A;  4TVM A;  6CTS A;  1A59 A;  1CSR A;  1CSI A;  2H12 A;  1CTS A;  1IXE A;  5CSC A;  4JAG A;  5CSC B;  1VGP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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