1A86A

Mmp8 with malonic and aspartic acid based inhibitor
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
158
structure length
158
Chain Sequence
NPKWERTNLTYRIRNYTPQLSEAEVERAIKDAFELWSVASPLIFTRISQGEADINIAFYQRDHGDNSPFDGPNGILAHAFQPGQGIGGDAHFDAEETWTNTSANYNLFLVAAHEFGHSLGLAHSSDPGALMYPNYAFRETSNYSLPQDDIDGIQAIYG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of malonic acid-based inhibitors bound to human neutrophil collagenase. A new binding mode explains apparently anomalous data.
pubmed rcsb
molecule keywords MMP-8
molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
total genus 46
structure length 158
sequence length 158
ec nomenclature ec 3.4.24.34: Neutrophil collagenase.
pdb deposition date 1998-04-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 1a86A00
2J0TA 2PJTA 1MMRA 1C7KA 1IABA 2W13A 4PKRA 2OW2A 1G49A 3Q2HA 1GE7A 1BQQM 1BSWA 1JAOA 1YOUA 5CUHA 830CA 1JH1A 2A8HA 4H1QA 1G4KA 3DSLA 2AIGP 3TSKA 1UTTA 1OO9A 1ASTA 4GQLA 1O0TA 3HB2P 1XFWA 1XURA 4PKQA 2WO9A 3F16A 1ND1A 3LE9A 3KMEA 1CIZA 4ILWD 3LJTA 3B92A 2USNA 4H2EA 3HY9A 3P1VA 1I76A 2RJPA 3KHIA 3DPEA 1JKYA 1H71P 1XFUA 1KUHA 1BZSA 3EWJA 2OXUA 1Y8JA 2QPJA 4AIGA 1ZTQA 1AF0A 3LMCA 2WOAA 1QIAA 2JSDA 1FBLA 5H8XA 1DMTA 2SRTA 1SMPA 4AYKA 1G12A 1R55A 1CQRA 2MZEA 3ELMA 2JNPA 1OM8A 3B8ZA 3E8RA 3O64A 1J7NA 3AYUA 1GO7P 1R1IA 3LQBA 1G9KA 4JPAA 4WKEA 3VI1A 1WNIA 2Y6CA 4DPEA 1GE6A 1GXDA 3EDIA 4PKTA 2DW1A 1UMSA 2CLTA 1GE5A 1UTZA 1EAKA 1GO8P 2W15A 4ZR5A 1KAPP 4PKWA 3EDHA 4IN9A 4WK7A 3F18A 4H76A 3DNGA 1K7GA 1YP1A 4R3VA 3LQ0A 5I0LA 2AYKA 3HBVP 3KEJA 4EFSA 5JMYA 2OY2A 2YB9A 4H3XA 5B5PA 5D1SA 3B2ZA 1UEAA 1CXVA 3HBUP 4H84A 1MMPA 1QJIA 3AIGA 1BM6A 3WV2A 3LGPA 3LILA 1FM1A 3KRYA 1AYKA 3KMCA 3OHLA 3WV1A 1SU3A 4JP4A 3RTTA 1R54A 4JA1A 3EDZA 1OM6A 2EROA 4WZVA 2DDYA 3N2VA 5D1TA 1RMZA 4XBHA 1JIWP 2WO8A 4AXQA 3TS4A 2RJQA 4H82A 1IAAA 5L7FA 1D5JA 5D2BA 1CGEA 3EHYA 1GKDA 1KUGA 1BKCI 5BPAA 4A7BA 1ZS0A 2OY4A 3EHXA 4WF6A 3SHIA 1EB6A 2K9CA 2X3BA 3V96B 2OZRA 2W12A 1ZP5A 3OHOA 4GWNA 3KWVC 1ZXCA 3ZUKA 5D1UA 1HFCA 2OXWA 2X7MA 1SLNA 5CXAA 2X3CA 1Y93A 1G05A 1OM7A 4FVLA 1QIBA 1PWUA 2TCLA 1YCMA 4PKSA 4FXYP 1D7XA 1JAPA 5LABA 1XUDA 3UVCA 2ERPA 1B8YA 5B5OA 2L0RA 1A86A 1JANA 1D8MA 2J83A 1Y0VA 2XS3A 1XFYA 2OXZA 1HY7A 3LIKA 1AKLA 1O0QA 1ROSA 5BOYA 3F17A 2DW0A 4GF1A 4H49A 3F19A 4DD8A 2E3XA 2Z2DA 4IJOA 1OMJA 5I4OA 2DDFA 2POJA 1CGFA 4GUYA 1R1HA 1S4BP 3N2UA 2OW1A 1EUBA 4G9LA 2MZHA 1XUCA 4XM8A 2W14A 1JIZA 4H30A 4CTHA 3LJZA 1MMBA 1L6JA 2XS4A 3G5CA 1HTDA 3LK8A 1IAEA 1MNCA 1DTHA 4ON1A 4PKVA 4XM7A 3HDAP 2YIGA 3G42A 1BKCA 1B3DA 1BUVM 4IUWA 2OVZA 1BKCE 2E2DA 3BA0A 3WV3A 4L19A 1JAQA 3TVCA 1KUKA 3DWBA 1BUDA 3LUMA 3ZVSA 3K7NA 5I12A 3KEKA 3RTSA 2N8RA 2JIHA 3AYKA 1I73A 3MA2A 4WKIA 1USNA 1C8TA 1ATLA 1Q3AA 4JIJA 1UMTA 2ERQA 1Z3JA 3TT4A 1QUAA 4FU4A 1SRPA 4Q1LA 2MZIA 4GR8A 1CGLA 3DL1A 1D8FA 5I43A 1QICA 3LKAA 2OI0A 1I1IP 2D1OA 5BOTA 1PWPA 5I2ZA 4DF9A 4G0DA 1CK7A 1PWVA 1YQYA 1XFXA 3LEAA 2DW2A 1R1JA 1ZXVA 1SATA 3L0VA 1IADA 1HOVA 2OW9A 2O36A 2W0DA 2OW0A 5D3CA 4HMAA 2K2GA 966CA 2JT6A 3ZXHA 2KRJA 3GBOA 1GKCA 3K7LA 1CAQA 3LIRA 4A3WA 3USNA 4QKZA 2MLRA 1XFVA 3I7GA 2X3AA 2Y6DA 1KUFA 2O3EA 4XCTA 3VTGA 3NX7A 1SLMA 5CZMA 2HU6A 1FLSA 4PKUA 1JJ9A 4AUOA 456CA 4HX3A 3P24A 2V4BA 2FV5A 1MMQA 1KBCA 1A85A 1BIWA 1HFSA 4XM6A 1PWQA 3EDGA 1IACA 1IAGA 3Q2GA 3DPFA 2JT5A 3I7IA 2MLSA 3U1RA 3LUNA 4FXQA 4I03A 1QJJA 1C3IA 5L79A 4L6TA 1OS9A 4GWMA 4I35A 5I3MA 4GR3A 3CKIA 3L0TA 1KUIA 2D1NA 4J4MA 5D7WA 1K7QA 1JK3A 1PWWA 2FV9A 2CKIA 1K7IA 3HDBA 3LJGA 4GR0A 1RM8A 1HV5A 1XFZA 1BQOA 4DV8A 4L63A 3O2XA 2OVXA 3F15A 2I47A 3F1AA 3KECA 3HY7A 3HYGA 1ZVXA 1OS2A 4JQGA
chains in the Genus database with same CATH superfamily
2J0TA 2PJTA 1MMRA 1C7KA 1IABA 2W13A 4PKRA 2OW2A 1G49A 3Q2HA 1GE7A 1BQQM 1BSWA 1JAOA 1YOUA 5CUHA 830CA 1JH1A 2A8HA 4H1QA 1G4KA 3DSLA 2AIGP 3TSKA 1UTTA 1OO9A 1ASTA 4GQLA 1O0TA 3HB2P 1XFWA 1XURA 4PKQA 2WO9A 3F16A 1ND1A 3LE9A 3KMEA 1CIZA 4ILWD 3LJTA 3B92A 2USNA 4H2EA 3HY9A 3P1VA 1I76A 2RJPA 3KHIA 3DPEA 1JKYA 1H71P 1XFUA 1KUHA 1BZSA 3EWJA 2OXUA 1Y8JA 2QPJA 4AIGA 1ZTQA 1AF0A 3LMCA 2WOAA 1QIAA 2JSDA 1FBLA 5H8XA 1DMTA 2SRTA 1SMPA 4AYKA 1G12A 1R55A 1CQRA 2MZEA 3ELMA 2JNPA 1OM8A 3B8ZA 3E8RA 3O64A 1J7NA 3AYUA 1GO7P 1R1IA 3LQBA 1G9KA 4JPAA 4WKEA 3VI1A 1WNIA 2Y6CA 4DPEA 1GE6A 1GXDA 3EDIA 4PKTA 2DW1A 1UMSA 2CLTA 1GE5A 1UTZA 1EAKA 1GO8P 2W15A 4ZR5A 1KAPP 4PKWA 3EDHA 4IN9A 4WK7A 3F18A 4H76A 3DNGA 1K7GA 1YP1A 4R3VA 2YUFA 3LQ0A 5I0LA 2AYKA 3HBVP 3KEJA 4EFSA 5JMYA 2OY2A 2YB9A 1OZ9A 4H3XA 5B5PA 5D1SA 3B2ZA 1UEAA 1CXVA 3HBUP 4H84A 1MMPA 1QJIA 3AIGA 1BM6A 3WV2A 3LGPA 3LILA 1FM1A 3KRYA 1AYKA 3KMCA 3OHLA 3WV1A 1SU3A 4JP4A 3RTTA 1R54A 4JA1A 3DTEA 3EDZA 1OM6A 2EROA 4WZVA 2DDYA 3N2VA 5D1TA 1RMZA 4XBHA 1JIWP 2WO8A 4AXQA 3TS4A 2RJQA 4H82A 1IAAA 5L7FA 1D5JA 5D2BA 1CGEA 3EHYA 1GKDA 1KUGA 1BKCI 5BPAA 1XM5A 4A7BA 1ZS0A 2OY4A 3EHXA 4WF6A 3SHIA 1EB6A 2K9CA 2X3BA 3V96B 2OZRA 2W12A 1ZP5A 3OHOA 4GWNA 3KWVC 1ZXCA 3ZUKA 5D1UA 1HFCA 2OXWA 2X7MA 1SLNA 5CXAA 2X3CA 1Y93A 1G05A 1OM7A 4FVLA 1QIBA 1PWUA 2TCLA 1YCMA 4PKSA 4FXYP 1D7XA 1JAPA 5LABA 1XUDA 3UVCA 2ERPA 1B8YA 5B5OA 2L0RA 1A86A 1JANA 1D8MA 2J83A 1Y0VA 2XS3A 1XFYA 2OXZA 1HY7A 3LIKA 1AKLA 1O0QA 1ROSA 5BOYA 3F17A 2DW0A 4GF1A 4H49A 3F19A 4DD8A 2E3XA 2Z2DA 1TVIA 4IJOA 1OMJA 5I4OA 2DDFA 2POJA 1CGFA 4GUYA 1R1HA 1S4BP 3N2UA 2OW1A 1EUBA 4G9LA 2MZHA 1XUCA 4XM8A 2W14A 1JIZA 4H30A 4CTHA 3LJZA 1MMBA 1L6JA 2XS4A 3G5CA 1HTDA 3LK8A 1IAEA 1MNCA 1DTHA 4ON1A 4PKVA 4XM7A 1XAXA 3HDAP 2YIGA 3G42A 1BKCA 1B3DA 1BUVM 4IUWA 2OVZA 1BKCE 2E2DA 3BA0A 3WV3A 4L19A 1JAQA 3TVCA 1KUKA 3DWBA 1BUDA 3LUMA 3ZVSA 3K7NA 5I12A 3KEKA 3RTSA 2N8RA 2JIHA 3AYKA 1I73A 3MA2A 4WKIA 1USNA 1C8TA 1ATLA 1Q3AA 4JIJA 1UMTA 2ERQA 1Z3JA 3TT4A 1QUAA 4FU4A 1SRPA 4Q1LA 2MZIA 4GR8A 1CGLA 3DL1A 1D8FA 5I43A 1QICA 2OI0A 3LKAA 1I1IP 2D1OA 5BOTA 1PWPA 5I2ZA 4DF9A 4G0DA 1CK7A 1PWVA 1YQYA 1XFXA 3LEAA 2DW2A 1R1JA 1ZXVA 1SATA 3L0VA 1IADA 1HOVA 2OW9A 2O36A 2W0DA 2OW0A 5D3CA 4HMAA 2K2GA 966CA 2JT6A 3ZXHA 2KRJA 3GBOA 1GKCA 3K7LA 1CAQA 3LIRA 4A3WA 3USNA 4QKZA 2MLRA 1XFVA 3I7GA 2X3AA 3DTKA 2Y6DA 1KUFA 3DTIA 2O3EA 4XCTA 3VTGA 4L7AA 3NX7A 1SLMA 5CZMA 2HU6A 1FLSA 4PKUA 1JJ9A 4AUOA 456CA 4HX3A 3P24A 2V4BA 2FV5A 1MMQA 1KBCA 1A85A 1BIWA 1HFSA 4XM6A 1PWQA 3EDGA 1IACA 1IAGA 3Q2GA 3DPFA 2JT5A 3I7IA 2MLSA 3U1RA 3LUNA 4FXQA 4I03A 1QJJA 1C3IA 5L79A 4L6TA 1OS9A 4GWMA 4I35A 5I3MA 4GR3A 3CKIA 3L0TA 1KUIA 2D1NA 4J4MA 5D7WA 1K7QA 1JK3A 1PWWA 2FV9A 2CKIA 1K7IA 3HDBA 3LJGA 4GR0A 1RM8A 1HV5A 1XFZA 1BQOA 4DV8A 4L63A 3O2XA 2OVXA 3F15A 2I47A 3F1AA 3KECA 3HY7A 3HYGA 1ZVXA 1OS2A 4JQGA
chains in the Genus database with same CATH topology
2J0TA 2PJTA 1MMRA 1C7KA 1IABA 2W13A 4PKRA 2OW2A 1G49A 3Q2HA 1GE7A 1BQQM 1BSWA 1JAOA 1YOUA 5CUHA 830CA 1JH1A 2A8HA 4H1QA 1G4KA 3DSLA 2AIGP 3TSKA 1UTTA 1OO9A 1ASTA 4GQLA 1O0TA 3HB2P 1XFWA 1XURA 4PKQA 2WO9A 3F16A 1ND1A 3LE9A 3KMEA 1CIZA 4ILWD 3LJTA 3B92A 2USNA 4H2EA 3HY9A 3P1VA 1I76A 2RJPA 3KHIA 3DPEA 1JKYA 1H71P 1XFUA 1KUHA 1BZSA 3EWJA 2OXUA 1Y8JA 2QPJA 4AIGA 1ZTQA 1AF0A 3LMCA 2WOAA 1QIAA 2JSDA 1FBLA 5H8XA 1DMTA 2SRTA 1SMPA 4AYKA 1G12A 1R55A 1CQRA 2MZEA 3ELMA 2JNPA 1OM8A 3B8ZA 3E8RA 3O64A 1J7NA 3AYUA 1GO7P 1R1IA 3LQBA 1G9KA 4JPAA 4WKEA 3VI1A 1WNIA 2Y6CA 4DPEA 1GE6A 1GXDA 3EDIA 4PKTA 2DW1A 1UMSA 2CLTA 1GE5A 1UTZA 1EAKA 1GO8P 2W15A 4ZR5A 1KAPP 4PKWA 3EDHA 4IN9A 4WK7A 3F18A 4H76A 3DNGA 1K7GA 1YP1A 4R3VA 2YUFA 3LQ0A 5I0LA 2AYKA 3HBVP 3KEJA 4EFSA 5JMYA 2OY2A 2YB9A 4H3XA 5B5PA 5D1SA 3B2ZA 1UEAA 1CXVA 3HBUP 4H84A 1MMPA 1QJIA 3AIGA 1BM6A 3WV2A 3LGPA 3LILA 1FM1A 3KRYA 1AYKA 3KMCA 3OHLA 3WV1A 1SU3A 4JP4A 3RTTA 1R54A 4JA1A 3DTEA 3EDZA 1OM6A 2EROA 4WZVA 2DDYA 3N2VA 5D1TA 1RMZA 4XBHA 1JIWP 2WO8A 4AXQA 3TS4A 2RJQA 4H82A 1IAAA 5L7FA 1D5JA 5D2BA 1CGEA 3EHYA 1GKDA 1KUGA 1BKCI 5BPAA 4A7BA 1ZS0A 2OY4A 3EHXA 4WF6A 3SHIA 1EB6A 2K9CA 2X3BA 3V96B 2OZRA 2W12A 1ZP5A 3OHOA 4GWNA 3KWVC 1ZXCA 3ZUKA 5D1UA 1HFCA 2OXWA 2X7MA 1SLNA 5CXAA 2X3CA 1Y93A 1G05A 1OM7A 4FVLA 1QIBA 1PWUA 2TCLA 1YCMA 4PKSA 4FXYP 1D7XA 1JAPA 5LABA 1XUDA 3UVCA 2ERPA 1B8YA 5B5OA 2L0RA 1A86A 1JANA 1D8MA 2J83A 1Y0VA 2XS3A 1XFYA 2OXZA 1HY7A 3LIKA 1AKLA 1O0QA 1ROSA 5BOYA 3F17A 2DW0A 4GF1A 4H49A 3F19A 4DD8A 2E3XA 2Z2DA 4IJOA 1OMJA 5I4OA 2DDFA 2POJA 1CGFA 4GUYA 1R1HA 1S4BP 3N2UA 2OW1A 1EUBA 4G9LA 2MZHA 1XUCA 4XM8A 2W14A 1JIZA 4H30A 4CTHA 3LJZA 1MMBA 1L6JA 2XS4A 3G5CA 1HTDA 3LK8A 1IAEA 1MNCA 1DTHA 4ON1A 4PKVA 4XM7A 3HDAP 2YIGA 3G42A 1BKCA 1B3DA 1BUVM 4IUWA 2OVZA 1BKCE 2E2DA 3BA0A 3WV3A 4L19A 1JAQA 3TVCA 1KUKA 3DWBA 1BUDA 3LUMA 3ZVSA 3K7NA 5I12A 3KEKA 3RTSA 2N8RA 2JIHA 3AYKA 1I73A 3MA2A 4WKIA 1USNA 1C8TA 1ATLA 1Q3AA 4JIJA 1UMTA 2ERQA 1Z3JA 3TT4A 1QUAA 4FU4A 1SRPA 4Q1LA 2MZIA 4GR8A 1CGLA 3DL1A 1D8FA 5I43A 1QICA 2OI0A 3LKAA 1I1IP 2D1OA 5BOTA 1PWPA 5I2ZA 4DF9A 4G0DA 1CK7A 1PWVA 1YQYA 1XFXA 3LEAA 2DW2A 1R1JA 1ZXVA 1SATA 3L0VA 1IADA 1HOVA 2OW9A 2O36A 2W0DA 2OW0A 5D3CA 4HMAA 2K2GA 966CA 2JT6A 3ZXHA 2KRJA 3GBOA 1GKCA 3K7LA 1CAQA 3LIRA 4A3WA 3USNA 4QKZA 2MLRA 1XFVA 3I7GA 2X3AA 3DTKA 2Y6DA 1KUFA 3DTIA 2O3EA 4XCTA 3VTGA 4L7AA 3NX7A 1SLMA 5CZMA 2HU6A 1FLSA 4PKUA 1JJ9A 4AUOA 456CA 4HX3A 3P24A 2V4BA 2FV5A 1MMQA 1KBCA 1A85A 1BIWA 1HFSA 4XM6A 1PWQA 3EDGA 1IACA 1IAGA 3Q2GA 3DPFA 2JT5A 3I7IA 2MLSA 3U1RA 3LUNA 4FXQA 4I03A 1QJJA 1C3IA 5L79A 4L6TA 1OS9A 4GWMA 4I35A 5I3MA 4GR3A 3CKIA 3L0TA 1KUIA 2D1NA 4J4MA 5D7WA 1K7QA 1JK3A 1PWWA 2FV9A 2CKIA 1K7IA 3HDBA 3LJGA 4GR0A 1RM8A 1HV5A 1XFZA 1BQOA 4DV8A 4L63A 3O2XA 2OVXA 3F15A 2I47A 3F1AA 3KECA 3HY7A 3HYGA 1ZVXA 1OS2A 4JQGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2J0T A;  2PJT A;  1MMR A;  1C7K A;  1IAB A;  2W13 A;  4PKR A;  2OW2 A;  1G49 A;  3Q2H A;  1GE7 A;  1BQQ M;  1BSW A;  1JAO A;  1YOU A;  5CUH A;  830C A;  1JH1 A;  2A8H A;  4H1Q A;  1G4K A;  3DSL A;  2AIG P;  3TSK A;  1UTT A;  1OO9 A;  1AST A;  4GQL A;  1O0T A;  3HB2 P;  1XFW A;  1XUR A;  4PKQ A;  2WO9 A;  3F16 A;  1ND1 A;  3LE9 A;  3KME A;  1CIZ A;  4ILW D;  3LJT A;  3B92 A;  2USN A;  4H2E A;  3HY9 A;  3P1V A;  1I76 A;  2RJP A;  3KHI A;  3DPE A;  1JKY A;  1H71 P;  1XFU A;  1KUH A;  1BZS A;  3EWJ A;  2OXU A;  1Y8J A;  2QPJ A;  4AIG A;  1ZTQ A;  1AF0 A;  3LMC A;  2WOA A;  1QIA A;  2JSD A;  1FBL A;  5H8X A;  1DMT A;  2SRT A;  1SMP A;  4AYK A;  1G12 A;  1R55 A;  1CQR A;  2MZE A;  3ELM A;  2JNP A;  1OM8 A;  3B8Z A;  3E8R A;  3O64 A;  1J7N A;  3AYU A;  1GO7 P;  1R1I A;  3LQB A;  1G9K A;  4JPA A;  4WKE A;  3VI1 A;  1WNI A;  2Y6C A;  4DPE A;  1GE6 A;  1GXD A;  3EDI A;  4PKT A;  2DW1 A;  1UMS A;  2CLT A;  1GE5 A;  1UTZ A;  1EAK A;  1GO8 P;  2W15 A;  4ZR5 A;  1KAP P;  4PKW A;  3EDH A;  4IN9 A;  4WK7 A;  3F18 A;  4H76 A;  3DNG A;  1K7G A;  1YP1 A;  4R3V A;  3LQ0 A;  5I0L A;  2AYK A;  3HBV P;  3KEJ A;  4EFS A;  5JMY A;  2OY2 A;  2YB9 A;  4H3X A;  5B5P A;  5D1S A;  3B2Z A;  1UEA A;  1CXV A;  3HBU P;  4H84 A;  1MMP A;  1QJI A;  3AIG A;  1BM6 A;  3WV2 A;  3LGP A;  3LIL A;  1FM1 A;  3KRY A;  1AYK A;  3KMC A;  3OHL A;  3WV1 A;  1SU3 A;  4JP4 A;  3RTT A;  1R54 A;  4JA1 A;  3EDZ A;  1OM6 A;  2ERO A;  4WZV A;  2DDY A;  3N2V A;  5D1T A;  1RMZ A;  4XBH A;  1JIW P;  2WO8 A;  4AXQ A;  3TS4 A;  2RJQ A;  4H82 A;  1IAA A;  5L7F A;  1D5J A;  5D2B A;  1CGE A;  3EHY A;  1GKD A;  1KUG A;  1BKC I;  5BPA A;  4A7B A;  1ZS0 A;  2OY4 A;  3EHX A;  4WF6 A;  3SHI A;  1EB6 A;  2K9C A;  2X3B A;  3V96 B;  2OZR A;  2W12 A;  1ZP5 A;  3OHO A;  4GWN A;  3KWV C;  1ZXC A;  3ZUK A;  5D1U A;  1HFC A;  2OXW A;  2X7M A;  1SLN A;  5CXA A;  2X3C A;  1Y93 A;  1G05 A;  1OM7 A;  4FVL A;  1QIB A;  1PWU A;  2TCL A;  1YCM A;  4PKS A;  4FXY P;  1D7X A;  1JAP A;  5LAB A;  1XUD A;  3UVC A;  2ERP A;  1B8Y A;  5B5O A;  2L0R A;  1A86 A;  1JAN A;  1D8M A;  2J83 A;  1Y0V A;  2XS3 A;  1XFY A;  2OXZ A;  1HY7 A;  3LIK A;  1AKL A;  1O0Q A;  1ROS A;  5BOY A;  3F17 A;  2DW0 A;  4GF1 A;  4H49 A;  3F19 A;  4DD8 A;  2E3X A;  2Z2D A;  4IJO A;  1OMJ A;  5I4O A;  2DDF A;  2POJ A;  1CGF A;  4GUY A;  1R1H A;  1S4B P;  3N2U A;  2OW1 A;  1EUB A;  4G9L A;  2MZH A;  1XUC A;  4XM8 A;  2W14 A;  1JIZ A;  4H30 A;  4CTH A;  3LJZ A;  1MMB A;  1L6J A;  2XS4 A;  3G5C A;  1HTD A;  3LK8 A;  1IAE A;  1MNC A;  1DTH A;  4ON1 A;  4PKV A;  4XM7 A;  3HDA P;  2YIG A;  3G42 A;  1BKC A;  1B3D A;  1BUV M;  4IUW A;  2OVZ A;  1BKC E;  2E2D A;  3BA0 A;  3WV3 A;  4L19 A;  1JAQ A;  3TVC A;  1KUK A;  3DWB A;  1BUD A;  3LUM A;  3ZVS A;  3K7N A;  5I12 A;  3KEK A;  3RTS A;  2N8R A;  2JIH A;  3AYK A;  1I73 A;  3MA2 A;  4WKI A;  1USN A;  1C8T A;  1ATL A;  1Q3A A;  4JIJ A;  1UMT A;  2ERQ A;  1Z3J A;  3TT4 A;  1QUA A;  4FU4 A;  1SRP A;  4Q1L A;  2MZI A;  4GR8 A;  1CGL A;  3DL1 A;  1D8F A;  5I43 A;  1QIC A;  3LKA A;  2OI0 A;  1I1I P;  2D1O A;  5BOT A;  1PWP A;  5I2Z A;  4DF9 A;  4G0D A;  1CK7 A;  1PWV A;  1YQY A;  1XFX A;  3LEA A;  2DW2 A;  1R1J A;  1ZXV A;  1SAT A;  3L0V A;  1IAD A;  1HOV A;  2OW9 A;  2O36 A;  2W0D A;  2OW0 A;  5D3C A;  4HMA A;  2K2G A;  966C A;  2JT6 A;  3ZXH A;  2KRJ A;  3GBO A;  1GKC A;  3K7L A;  1CAQ A;  3LIR A;  4A3W A;  3USN A;  4QKZ A;  2MLR A;  1XFV A;  3I7G A;  2X3A A;  2Y6D A;  1KUF A;  2O3E A;  4XCT A;  3VTG A;  3NX7 A;  1SLM A;  5CZM A;  2HU6 A;  1FLS A;  4PKU A;  1JJ9 A;  4AUO A;  456C A;  4HX3 A;  3P24 A;  2V4B A;  2FV5 A;  1MMQ A;  1KBC A;  1A85 A;  1BIW A;  1HFS A;  4XM6 A;  1PWQ A;  3EDG A;  1IAC A;  1IAG A;  3Q2G A;  3DPF A;  2JT5 A;  3I7I A;  2MLS A;  3U1R A;  3LUN A;  4FXQ A;  4I03 A;  1QJJ A;  1C3I A;  5L79 A;  4L6T A;  1OS9 A;  4GWM A;  4I35 A;  5I3M A;  4GR3 A;  3CKI A;  3L0T A;  1KUI A;  2D1N A;  4J4M A;  5D7W A;  1K7Q A;  1JK3 A;  1PWW A;  2FV9 A;  2CKI A;  1K7I A;  3HDB A;  3LJG A;  4GR0 A;  1RM8 A;  1HV5 A;  1XFZ A;  1BQO A;  4DV8 A;  4L63 A;  3O2X A;  2OVX A;  3F15 A;  2I47 A;  3F1A A;  3KEC A;  3HY7 A;  3HYG A;  1ZVX A;  1OS2 A;  4JQG A; 
#chains in the Genus database with same CATH topology
 2J0T A;  2PJT A;  1MMR A;  1C7K A;  1IAB A;  2W13 A;  4PKR A;  2OW2 A;  1G49 A;  3Q2H A;  1GE7 A;  1BQQ M;  1BSW A;  1JAO A;  1YOU A;  5CUH A;  830C A;  1JH1 A;  2A8H A;  4H1Q A;  1G4K A;  3DSL A;  2AIG P;  3TSK A;  1UTT A;  1OO9 A;  1AST A;  4GQL A;  1O0T A;  3HB2 P;  1XFW A;  1XUR A;  4PKQ A;  2WO9 A;  3F16 A;  1ND1 A;  3LE9 A;  3KME A;  1CIZ A;  4ILW D;  3LJT A;  3B92 A;  2USN A;  4H2E A;  3HY9 A;  3P1V A;  1I76 A;  2RJP A;  3KHI A;  3DPE A;  1JKY A;  1H71 P;  1XFU A;  1KUH A;  1BZS A;  3EWJ A;  2OXU A;  1Y8J A;  2QPJ A;  4AIG A;  1ZTQ A;  1AF0 A;  3LMC A;  2WOA A;  1QIA A;  2JSD A;  1FBL A;  5H8X A;  1DMT A;  2SRT A;  1SMP A;  4AYK A;  1G12 A;  1R55 A;  1CQR A;  2MZE A;  3ELM A;  2JNP A;  1OM8 A;  3B8Z A;  3E8R A;  3O64 A;  1J7N A;  3AYU A;  1GO7 P;  1R1I A;  3LQB A;  1G9K A;  4JPA A;  4WKE A;  3VI1 A;  1WNI A;  2Y6C A;  4DPE A;  1GE6 A;  1GXD A;  3EDI A;  4PKT A;  2DW1 A;  1UMS A;  2CLT A;  1GE5 A;  1UTZ A;  1EAK A;  1GO8 P;  2W15 A;  4ZR5 A;  1KAP P;  4PKW A;  3EDH A;  4IN9 A;  4WK7 A;  3F18 A;  4H76 A;  3DNG A;  1K7G A;  1YP1 A;  4R3V A;  2YUF A;  3LQ0 A;  5I0L A;  2AYK A;  3HBV P;  3KEJ A;  4EFS A;  5JMY A;  2OY2 A;  2YB9 A;  1OZ9 A;  4H3X A;  5B5P A;  5D1S A;  3B2Z A;  1UEA A;  1CXV A;  3HBU P;  4H84 A;  1MMP A;  1QJI A;  3AIG A;  1BM6 A;  3WV2 A;  3LGP A;  3LIL A;  1FM1 A;  3KRY A;  1AYK A;  3KMC A;  3OHL A;  3WV1 A;  1SU3 A;  4JP4 A;  3RTT A;  1R54 A;  4JA1 A;  3DTE A;  3EDZ A;  1OM6 A;  2ERO A;  4WZV A;  2DDY A;  3N2V A;  5D1T A;  1RMZ A;  4XBH A;  1JIW P;  2WO8 A;  4AXQ A;  3TS4 A;  2RJQ A;  4H82 A;  1IAA A;  5L7F A;  1D5J A;  5D2B A;  1CGE A;  3EHY A;  1GKD A;  1KUG A;  1BKC I;  5BPA A;  1XM5 A;  4A7B A;  1ZS0 A;  2OY4 A;  3EHX A;  4WF6 A;  3SHI A;  1EB6 A;  2K9C A;  2X3B A;  3V96 B;  2OZR A;  2W12 A;  1ZP5 A;  3OHO A;  4GWN A;  3KWV C;  1ZXC A;  3ZUK A;  5D1U A;  1HFC A;  2OXW A;  2X7M A;  1SLN A;  5CXA A;  2X3C A;  1Y93 A;  1G05 A;  1OM7 A;  4FVL A;  1QIB A;  1PWU A;  2TCL A;  1YCM A;  4PKS A;  4FXY P;  1D7X A;  1JAP A;  5LAB A;  1XUD A;  3UVC A;  2ERP A;  1B8Y A;  5B5O A;  2L0R A;  1A86 A;  1JAN A;  1D8M A;  2J83 A;  1Y0V A;  2XS3 A;  1XFY A;  2OXZ A;  1HY7 A;  3LIK A;  1AKL A;  1O0Q A;  1ROS A;  5BOY A;  3F17 A;  2DW0 A;  4GF1 A;  4H49 A;  3F19 A;  4DD8 A;  2E3X A;  2Z2D A;  1TVI A;  4IJO A;  1OMJ A;  5I4O A;  2DDF A;  2POJ A;  1CGF A;  4GUY A;  1R1H A;  1S4B P;  3N2U A;  2OW1 A;  1EUB A;  4G9L A;  2MZH A;  1XUC A;  4XM8 A;  2W14 A;  1JIZ A;  4H30 A;  4CTH A;  3LJZ A;  1MMB A;  1L6J A;  2XS4 A;  3G5C A;  1HTD A;  3LK8 A;  1IAE A;  1MNC A;  1DTH A;  4ON1 A;  4PKV A;  4XM7 A;  1XAX A;  3HDA P;  2YIG A;  3G42 A;  1BKC A;  1B3D A;  1BUV M;  4IUW A;  2OVZ A;  1BKC E;  2E2D A;  3BA0 A;  3WV3 A;  4L19 A;  1JAQ A;  3TVC A;  1KUK A;  3DWB A;  1BUD A;  3LUM A;  3ZVS A;  3K7N A;  5I12 A;  3KEK A;  3RTS A;  2N8R A;  2JIH A;  3AYK A;  1I73 A;  3MA2 A;  4WKI A;  1USN A;  1C8T A;  1ATL A;  1Q3A A;  4JIJ A;  1UMT A;  2ERQ A;  1Z3J A;  3TT4 A;  1QUA A;  4FU4 A;  1SRP A;  4Q1L A;  2MZI A;  4GR8 A;  1CGL A;  3DL1 A;  1D8F A;  5I43 A;  1QIC A;  2OI0 A;  3LKA A;  1I1I P;  2D1O A;  5BOT A;  1PWP A;  5I2Z A;  4DF9 A;  4G0D A;  1CK7 A;  1PWV A;  1YQY A;  1XFX A;  3LEA A;  2DW2 A;  1R1J A;  1ZXV A;  1SAT A;  3L0V A;  1IAD A;  1HOV A;  2OW9 A;  2O36 A;  2W0D A;  2OW0 A;  5D3C A;  4HMA A;  2K2G A;  966C A;  2JT6 A;  3ZXH A;  2KRJ A;  3GBO A;  1GKC A;  3K7L A;  1CAQ A;  3LIR A;  4A3W A;  3USN A;  4QKZ A;  2MLR A;  1XFV A;  3I7G A;  2X3A A;  3DTK A;  2Y6D A;  1KUF A;  3DTI A;  2O3E A;  4XCT A;  3VTG A;  4L7A A;  3NX7 A;  1SLM A;  5CZM A;  2HU6 A;  1FLS A;  4PKU A;  1JJ9 A;  4AUO A;  456C A;  4HX3 A;  3P24 A;  2V4B A;  2FV5 A;  1MMQ A;  1KBC A;  1A85 A;  1BIW A;  1HFS A;  4XM6 A;  1PWQ A;  3EDG A;  1IAC A;  1IAG A;  3Q2G A;  3DPF A;  2JT5 A;  3I7I A;  2MLS A;  3U1R A;  3LUN A;  4FXQ A;  4I03 A;  1QJJ A;  1C3I A;  5L79 A;  4L6T A;  1OS9 A;  4GWM A;  4I35 A;  5I3M A;  4GR3 A;  3CKI A;  3L0T A;  1KUI A;  2D1N A;  4J4M A;  5D7W A;  1K7Q A;  1JK3 A;  1PWW A;  2FV9 A;  2CKI A;  1K7I A;  3HDB A;  3LJG A;  4GR0 A;  1RM8 A;  1HV5 A;  1XFZ A;  1BQO A;  4DV8 A;  4L63 A;  3O2X A;  2OVX A;  3F15 A;  2I47 A;  3F1A A;  3KEC A;  3HY7 A;  3HYG A;  1ZVX A;  1OS2 A;  4JQG A; 
#chains in the Genus database with same CATH homology
 2J0T A;  2PJT A;  1MMR A;  1C7K A;  1IAB A;  2W13 A;  4PKR A;  2OW2 A;  1G49 A;  3Q2H A;  1GE7 A;  1BQQ M;  1BSW A;  1JAO A;  1YOU A;  5CUH A;  830C A;  1JH1 A;  2A8H A;  4H1Q A;  1G4K A;  3DSL A;  2AIG P;  3TSK A;  1UTT A;  1OO9 A;  1AST A;  4GQL A;  1O0T A;  3HB2 P;  1XFW A;  1XUR A;  4PKQ A;  2WO9 A;  3F16 A;  1ND1 A;  3LE9 A;  3KME A;  1CIZ A;  4ILW D;  3LJT A;  3B92 A;  2USN A;  4H2E A;  3HY9 A;  3P1V A;  1I76 A;  2RJP A;  3KHI A;  3DPE A;  1JKY A;  1H71 P;  1XFU A;  1KUH A;  1BZS A;  3EWJ A;  2OXU A;  1Y8J A;  2QPJ A;  4AIG A;  1ZTQ A;  1AF0 A;  3LMC A;  2WOA A;  1QIA A;  2JSD A;  1FBL A;  5H8X A;  1DMT A;  2SRT A;  1SMP A;  4AYK A;  1G12 A;  1R55 A;  1CQR A;  2MZE A;  3ELM A;  2JNP A;  1OM8 A;  3B8Z A;  3E8R A;  3O64 A;  1J7N A;  3AYU A;  1GO7 P;  1R1I A;  3LQB A;  1G9K A;  4JPA A;  4WKE A;  3VI1 A;  1WNI A;  2Y6C A;  4DPE A;  1GE6 A;  1GXD A;  3EDI A;  4PKT A;  2DW1 A;  1UMS A;  2CLT A;  1GE5 A;  1UTZ A;  1EAK A;  1GO8 P;  2W15 A;  4ZR5 A;  1KAP P;  4PKW A;  3EDH A;  4IN9 A;  4WK7 A;  3F18 A;  4H76 A;  3DNG A;  1K7G A;  1YP1 A;  4R3V A;  2YUF A;  3LQ0 A;  5I0L A;  2AYK A;  3HBV P;  3KEJ A;  4EFS A;  5JMY A;  2OY2 A;  2YB9 A;  4H3X A;  5B5P A;  5D1S A;  3B2Z A;  1UEA A;  1CXV A;  3HBU P;  4H84 A;  1MMP A;  1QJI A;  3AIG A;  1BM6 A;  3WV2 A;  3LGP A;  3LIL A;  1FM1 A;  3KRY A;  1AYK A;  3KMC A;  3OHL A;  3WV1 A;  1SU3 A;  4JP4 A;  3RTT A;  1R54 A;  4JA1 A;  3DTE A;  3EDZ A;  1OM6 A;  2ERO A;  4WZV A;  2DDY A;  3N2V A;  5D1T A;  1RMZ A;  4XBH A;  1JIW P;  2WO8 A;  4AXQ A;  3TS4 A;  2RJQ A;  4H82 A;  1IAA A;  5L7F A;  1D5J A;  5D2B A;  1CGE A;  3EHY A;  1GKD A;  1KUG A;  1BKC I;  5BPA A;  4A7B A;  1ZS0 A;  2OY4 A;  3EHX A;  4WF6 A;  3SHI A;  1EB6 A;  2K9C A;  2X3B A;  3V96 B;  2OZR A;  2W12 A;  1ZP5 A;  3OHO A;  4GWN A;  3KWV C;  1ZXC A;  3ZUK A;  5D1U A;  1HFC A;  2OXW A;  2X7M A;  1SLN A;  5CXA A;  2X3C A;  1Y93 A;  1G05 A;  1OM7 A;  4FVL A;  1QIB A;  1PWU A;  2TCL A;  1YCM A;  4PKS A;  4FXY P;  1D7X A;  1JAP A;  5LAB A;  1XUD A;  3UVC A;  2ERP A;  1B8Y A;  5B5O A;  2L0R A;  1A86 A;  1JAN A;  1D8M A;  2J83 A;  1Y0V A;  2XS3 A;  1XFY A;  2OXZ A;  1HY7 A;  3LIK A;  1AKL A;  1O0Q A;  1ROS A;  5BOY A;  3F17 A;  2DW0 A;  4GF1 A;  4H49 A;  3F19 A;  4DD8 A;  2E3X A;  2Z2D A;  4IJO A;  1OMJ A;  5I4O A;  2DDF A;  2POJ A;  1CGF A;  4GUY A;  1R1H A;  1S4B P;  3N2U A;  2OW1 A;  1EUB A;  4G9L A;  2MZH A;  1XUC A;  4XM8 A;  2W14 A;  1JIZ A;  4H30 A;  4CTH A;  3LJZ A;  1MMB A;  1L6J A;  2XS4 A;  3G5C A;  1HTD A;  3LK8 A;  1IAE A;  1MNC A;  1DTH A;  4ON1 A;  4PKV A;  4XM7 A;  3HDA P;  2YIG A;  3G42 A;  1BKC A;  1B3D A;  1BUV M;  4IUW A;  2OVZ A;  1BKC E;  2E2D A;  3BA0 A;  3WV3 A;  4L19 A;  1JAQ A;  3TVC A;  1KUK A;  3DWB A;  1BUD A;  3LUM A;  3ZVS A;  3K7N A;  5I12 A;  3KEK A;  3RTS A;  2N8R A;  2JIH A;  3AYK A;  1I73 A;  3MA2 A;  4WKI A;  1USN A;  1C8T A;  1ATL A;  1Q3A A;  4JIJ A;  1UMT A;  2ERQ A;  1Z3J A;  3TT4 A;  1QUA A;  4FU4 A;  1SRP A;  4Q1L A;  2MZI A;  4GR8 A;  1CGL A;  3DL1 A;  1D8F A;  5I43 A;  1QIC A;  2OI0 A;  3LKA A;  1I1I P;  2D1O A;  5BOT A;  1PWP A;  5I2Z A;  4DF9 A;  4G0D A;  1CK7 A;  1PWV A;  1YQY A;  1XFX A;  3LEA A;  2DW2 A;  1R1J A;  1ZXV A;  1SAT A;  3L0V A;  1IAD A;  1HOV A;  2OW9 A;  2O36 A;  2W0D A;  2OW0 A;  5D3C A;  4HMA A;  2K2G A;  966C A;  2JT6 A;  3ZXH A;  2KRJ A;  3GBO A;  1GKC A;  3K7L A;  1CAQ A;  3LIR A;  4A3W A;  3USN A;  4QKZ A;  2MLR A;  1XFV A;  3I7G A;  2X3A A;  3DTK A;  2Y6D A;  1KUF A;  3DTI A;  2O3E A;  4XCT A;  3VTG A;  4L7A A;  3NX7 A;  1SLM A;  5CZM A;  2HU6 A;  1FLS A;  4PKU A;  1JJ9 A;  4AUO A;  456C A;  4HX3 A;  3P24 A;  2V4B A;  2FV5 A;  1MMQ A;  1KBC A;  1A85 A;  1BIW A;  1HFS A;  4XM6 A;  1PWQ A;  3EDG A;  1IAC A;  1IAG A;  3Q2G A;  3DPF A;  2JT5 A;  3I7I A;  2MLS A;  3U1R A;  3LUN A;  4FXQ A;  4I03 A;  1QJJ A;  1C3I A;  5L79 A;  4L6T A;  1OS9 A;  4GWM A;  4I35 A;  5I3M A;  4GR3 A;  3CKI A;  3L0T A;  1KUI A;  2D1N A;  4J4M A;  5D7W A;  1K7Q A;  1JK3 A;  1PWW A;  2FV9 A;  2CKI A;  1K7I A;  3HDB A;  3LJG A;  4GR0 A;  1RM8 A;  1HV5 A;  1XFZ A;  1BQO A;  4DV8 A;  4L63 A;  3O2X A;  2OVX A;  3F15 A;  2I47 A;  3F1A A;  3KEC A;  3HY7 A;  3HYG A;  1ZVX A;  1OS2 A;  4JQG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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