1AERA

Domain iii of pseudomonas aeruginosa exotoxin complexed with beta-tad
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
211
structure length
205
Chain Sequence
AFLGDGGDVSFSTRGTQNWTVERLLQAHRQLEERGYVFVGYHGTFLEAAQSIVFGGVRAAIWRGFYIAGDPALAYGYAQDQEPDARGRIRNGALLRVYVPRSSLPGFYRTSLTLAAPEAAGEVERLIGHPLPLRLDAITGPEEEGGRLETILGWPLAERTVVIPSAIPTDPRNVGGDLDPSSIPDKEQAISALPDYASQPGKPPR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Adp-ribosylation
molecule keywords EXOTOXIN A
publication title Crystal structure of the catalytic domain of Pseudomonas exotoxin A complexed with a nicotinamide adenine dinucleotide analog: implications for the activation process and for ADP ribosylation
pubmed doi rcsb
source organism Pseudomonas aeruginosa
total genus 46
structure length 205
sequence length 211
chains with identical sequence B
ec nomenclature ec 2.4.2.36: NAD(+)--diphthamide ADP-ribosyltransferase.
pdb deposition date 1995-12-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF09009 Exotox-A_cataly Exotoxin A catalytic
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.175.10 Alpha Beta Alpha-Beta Complex Diphtheria Toxin; domain 1 Diphtheria Toxin, domain 1 1aerA00
3KI4A 3B78B 1TOXA 1IKPA 2Q6MA 1AERA 3NY6A 4AE0A 3B8HB 4OW6A 3KI3A 2Q5TA 2ZITB 5I82A 1DMAA 1ZM2B 1F0LA 1DTPA 4AE1A 1SGKA 1IKQA 3Q9OA 3B82B 1XDTT 3ESSA 1ZM3B 3KI0A 3KI5A 1ZM9B 3KI1A 1MDTA 3KI6A 1ZM4B 1DDTA 1XK9A 3KI2A 3KI7A
chains in the Genus database with same CATH superfamily
3KI4A 3B78B 1TOXA 1IKPA 2Q6MA 1AERA 3NY6A 4AE0A 3B8HB 4OW6A 3KI3A 2Q5TA 2ZITB 5I82A 1DMAA 1ZM2B 1F0LA 1DTPA 4AE1A 1SGKA 1IKQA 3Q9OA 3B82B 1XDTT 3ESSA 1ZM3B 3KI0A 3KI5A 1ZM9B 3KI1A 1MDTA 3KI6A 1ZM4B 1DDTA 1XK9A 3KI2A 3KI7A
chains in the Genus database with same CATH topology
3KI4A 3B78B 1TOXA 1IKPA 2Q6MA 1AERA 3NY6A 4AE0A 3B8HB 4OW6A 3KI3A 2Q5TA 2ZITB 5I82A 1DMAA 1ZM2B 1F0LA 1DTPA 4AE1A 1SGKA 1IKQA 3Q9OA 3B82B 1XDTT 3ESSA 1ZM3B 3KI0A 3KI5A 1ZM9B 3KI1A 1MDTA 3KI6A 1ZM4B 1DDTA 1XK9A 3KI2A 3KI7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3KI4 A;  3B78 B;  1TOX A;  1IKP A;  2Q6M A;  1AER A;  3NY6 A;  4AE0 A;  3B8H B;  4OW6 A;  3KI3 A;  2Q5T A;  2ZIT B;  5I82 A;  1DMA A;  1ZM2 B;  1F0L A;  1DTP A;  4AE1 A;  1SGK A;  1IKQ A;  3Q9O A;  3B82 B;  1XDT T;  3ESS A;  1ZM3 B;  3KI0 A;  3KI5 A;  1ZM9 B;  3KI1 A;  1MDT A;  3KI6 A;  1ZM4 B;  1DDT A;  1XK9 A;  3KI2 A;  3KI7 A; 
#chains in the Genus database with same CATH topology
 3KI4 A;  3B78 B;  1TOX A;  1IKP A;  2Q6M A;  1AER A;  3NY6 A;  4AE0 A;  3B8H B;  4OW6 A;  3KI3 A;  2Q5T A;  2ZIT B;  5I82 A;  1DMA A;  1ZM2 B;  1F0L A;  1DTP A;  4AE1 A;  1SGK A;  1IKQ A;  3Q9O A;  3B82 B;  1XDT T;  3ESS A;  1ZM3 B;  3KI0 A;  3KI5 A;  1ZM9 B;  3KI1 A;  1MDT A;  3KI6 A;  1ZM4 B;  1DDT A;  1XK9 A;  3KI2 A;  3KI7 A; 
#chains in the Genus database with same CATH homology
 3KI4 A;  3B78 B;  1TOX A;  1IKP A;  2Q6M A;  1AER A;  3NY6 A;  4AE0 A;  3B8H B;  4OW6 A;  3KI3 A;  2Q5T A;  2ZIT B;  5I82 A;  1DMA A;  1ZM2 B;  1F0L A;  1DTP A;  4AE1 A;  1SGK A;  1IKQ A;  3Q9O A;  3B82 B;  1XDT T;  3ESS A;  1ZM3 B;  3KI0 A;  3KI5 A;  1ZM9 B;  3KI1 A;  1MDT A;  3KI6 A;  1ZM4 B;  1DDT A;  1XK9 A;  3KI2 A;  3KI7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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