1AGRE

Complex of alf4-activated gi-alpha-1 with rgs4
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
128
structure length
128
Chain Sequence
VSQEEVKKWAESLENLINHECGLAAFKAFLKSEYSEENIDFWISCEEYKKIKSPSKLSPKAKKIYNEFISVQATKEVNLDSCTREETSRNMLEPTITCFDEAQKKIFNLMEKDSYRRFLKSRFYLDLT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Complex (signal transduction/regulator)
molecule keywords GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)
publication title Structure of RGS4 bound to AlF4--activated G(i alpha1): stabilization of the transition state for GTP hydrolysis.
pubmed doi rcsb
source organism Rattus norvegicus
total genus 50
structure length 128
sequence length 128
chains with identical sequence H
ec nomenclature
pdb deposition date 1997-03-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 1agrE02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 1agrE01
2BV1A 4TNDA 3CIKA 3KRXA 2OWIA 1EZYA 1AGRE 1FQJB 2CRPA 2D9JA 2ODEB 3PVUA 5HE1A 3KRWA 3NYNA 2JNUA 1DK8A 5HE2A 3PVWA 2V4ZB 2IK8B 2OJ4A 3C7KB 5HE3A 2JM5A 2IHDA 4MK0A 3PSCA 3UZTA 1EMUA 3NYOA 4PNKA 4TNBA 2AF0A 4EKDB 2BT2A 3C7LA 5DO9B 1EZTA 1OMWA 1FQIA 1FQKB 5HE0A 1CMZA 2DLVA 3V5WA 2BCJA 2GTPC 2IHBB 2EBZA
chains in the Genus database with same CATH superfamily
5REQB 2BV1A 4TNDA 3CIKA 3KRXA 2OWIA 3I5QA 1EZYA 1AGRE 1FQJB 2CRPA 2D9JA 2ODEB 3PVUA 5HE1A 3KRWA 3NYNA 2JNUA 1DK8A 5HE2A 3PVWA 2V4ZB 2IK8B 2OJ4A 3C7KB 5HE3A 2JM5A 2IHDA 4HTEA 4MK0A 3PSCA 3UZTA 1EMUA 3NYOA 4PNKA 4TNBA 2AF0A 4EKDB 3QYFA 2BT2A 3C7LA 5DO9B 1EZTA 1OMWA 1FQIA 1FQKB 5HE0A 1CMZA 2DLVA 3V5WA 2BCJA 2GTPC 2IHBB 2EBZA
chains in the Genus database with same CATH topology
5REQB 2BV1A 4TNDA 3CIKA 3KRXA 2OWIA 1EZYA 1AGRE 1FQJB 2CRPA 2D9JA 2ODEB 3PVUA 5HE1A 3KRWA 3NYNA 2JNUA 1DK8A 5HE2A 3PVWA 2V4ZB 2IK8B 2OJ4A 3C7KB 5HE3A 2JM5A 2IHDA 4MK0A 3PSCA 3UZTA 1EMUA 3NYOA 4PNKA 4TNBA 2AF0A 4EKDB 3QYFA 2BT2A 3C7LA 5DO9B 1EZTA 1OMWA 1FQIA 1FQKB 5HE0A 1CMZA 2DLVA 3V5WA 2BCJA 2GTPC 2IHBB 2EBZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2BV1 A;  4TND A;  3CIK A;  3KRX A;  2OWI A;  1EZY A;  1AGR E;  1FQJ B;  2CRP A;  2D9J A;  2ODE B;  3PVU A;  5HE1 A;  3KRW A;  3NYN A;  2JNU A;  1DK8 A;  5HE2 A;  3PVW A;  2V4Z B;  2IK8 B;  2OJ4 A;  3C7K B;  5HE3 A;  2JM5 A;  2IHD A;  4MK0 A;  3PSC A;  3UZT A;  1EMU A;  3NYO A;  4PNK A;  4TNB A;  2AF0 A;  4EKD B;  2BT2 A;  3C7L A;  5DO9 B;  1EZT A;  1OMW A;  1FQI A;  1FQK B;  5HE0 A;  1CMZ A;  2DLV A;  3V5W A;  2BCJ A;  2GTP C;  2IHB B;  2EBZ A; 
#chains in the Genus database with same CATH topology
 5REQ B;  2BV1 A;  4TND A;  3CIK A;  3KRX A;  2OWI A;  3I5Q A;  1EZY A;  1AGR E;  1FQJ B;  2CRP A;  2D9J A;  2ODE B;  3PVU A;  5HE1 A;  3KRW A;  3NYN A;  2JNU A;  1DK8 A;  5HE2 A;  3PVW A;  2V4Z B;  2IK8 B;  2OJ4 A;  3C7K B;  5HE3 A;  2JM5 A;  2IHD A;  4HTE A;  4MK0 A;  3PSC A;  3UZT A;  1EMU A;  3NYO A;  4PNK A;  4TNB A;  2AF0 A;  4EKD B;  3QYF A;  2BT2 A;  3C7L A;  5DO9 B;  1EZT A;  1OMW A;  1FQI A;  1FQK B;  5HE0 A;  1CMZ A;  2DLV A;  3V5W A;  2BCJ A;  2GTP C;  2IHB B;  2EBZ A; 
#chains in the Genus database with same CATH homology
 5REQ B;  2BV1 A;  4TND A;  3CIK A;  3KRX A;  2OWI A;  1EZY A;  1AGR E;  1FQJ B;  2CRP A;  2D9J A;  2ODE B;  3PVU A;  5HE1 A;  3KRW A;  3NYN A;  2JNU A;  1DK8 A;  5HE2 A;  3PVW A;  2V4Z B;  2IK8 B;  2OJ4 A;  3C7K B;  5HE3 A;  2JM5 A;  2IHD A;  4MK0 A;  3PSC A;  3UZT A;  1EMU A;  3NYO A;  4PNK A;  4TNB A;  2AF0 A;  4EKD B;  3QYF A;  2BT2 A;  3C7L A;  5DO9 B;  1EZT A;  1OMW A;  1FQI A;  1FQK B;  5HE0 A;  1CMZ A;  2DLV A;  3V5W A;  2BCJ A;  2GTP C;  2IHB B;  2EBZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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