1AK4C

Human cyclophilin a bound to the amino-terminal domain of hiv-1 capsid
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
145
structure length
145
Chain Sequence
PIVQNLQGQMVHQAISPRTLNAWVKVVEEKAFSPEVIPMFSALSEGATPQDLNTMLNTVGGHQAAMQMLKETINEEAAEWDRLHPVHAGPIAPGQMREPRGSDIAGTTSTLQEQIGWMTHNPPIPVGEIYKRWIILGLNKIVRMY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal structure of human cyclophilin A bound to the amino-terminal domain of HIV-1 capsid.
pubmed doi rcsb
molecule tags Viral protein/isomerase
source organism Homo sapiens
molecule keywords CYCLOPHILIN A
total genus 45
structure length 145
sequence length 145
chains with identical sequence D
ec nomenclature ec 2.7.7.49: RNA-directed DNA polymerase.
pdb deposition date 1997-05-28
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.375.10 Mainly Alpha Orthogonal Bundle Human Immunodeficiency Virus Type 1 Capsid Protein Human Immunodeficiency Virus Type 1 Capsid Protein 1ak4C00
1EM9A 1G03A 4WYMA 2XDEA 1M9CC 5HGMA 4U0FA 5JPAA 4NX4C 4HTWA 4E91A 2LF4A 4PH2A 2M8NA 4XRQA 4E92A 5HGLA 2V4XA 3H47A 4U0EA 4XFZA 3MGEA 4INBA 1U7KA 2JPRA 4U0CA 2GOLB 1M9XC 2PWMA 2PWOA 1L6NA 2M8PA 2XGUA 4XFYA 5HGNA 3P05A 1QRJA 4DGEC 2M8LA 1AFVA 4XROA 4LQWC 1GWPA 1E6JP 4DGAC 1M9YC 1EIAA 3H4EA 4U0DA 1AK4C 2XGYA 2PXRC 2Y4ZA 4U0AA 3NTEA 2KGFA 2WLVA 4QNBA 1P7NA 4PH3A 2EIAA 4XFXA 1D1DA 2X2DD 4B4NA 2X82A 4U0BA 1M9FC 4PH0A 2GONA 2WLVB 1M9DC 3BP9A 4J93A 1M9EC 2XGVA 5HGKA 2X83A 5HGOA
chains in the Genus database with same CATH superfamily
1EM9A 1G03A 4WYMA 2XDEA 1M9CC 5HGMA 4U0FA 5JPAA 4NX4C 4HTWA 4E91A 2LF4A 4PH2A 2M8NA 4XRQA 4E92A 5HGLA 2V4XA 3H47A 4U0EA 4XFZA 3MGEA 4INBA 1U7KA 2JPRA 4U0CA 2GOLB 1M9XC 2PWMA 2PWOA 1L6NA 2M8PA 2XGUA 4XFYA 5HGNA 3P05A 1QRJA 4DGEC 2M8LA 1AFVA 4XROA 4LQWC 1GWPA 1E6JP 4DGAC 1M9YC 1EIAA 3H4EA 4U0DA 1AK4C 2XGYA 2PXRC 2Y4ZA 4U0AA 3NTEA 2KGFA 2WLVA 4QNBA 1P7NA 4PH3A 2EIAA 4XFXA 1D1DA 2X2DD 4B4NA 2X82A 4U0BA 1M9FC 4PH0A 2GONA 2WLVB 1M9DC 3BP9A 4J93A 1M9EC 2XGVA 5HGKA 2X83A 5HGOA
chains in the Genus database with same CATH topology
1EM9A 1G03A 4WYMA 2XDEA 1M9CC 5HGMA 4U0FA 5JPAA 4NX4C 4HTWA 4E91A 2LF4A 4PH2A 2M8NA 4XRQA 4E92A 5HGLA 2V4XA 3H47A 4U0EA 4XFZA 3MGEA 4INBA 1U7KA 2JPRA 4U0CA 2GOLB 1M9XC 2PWMA 2PWOA 1L6NA 2M8PA 2XGUA 4XFYA 5HGNA 3P05A 1QRJA 4DGEC 2M8LA 1AFVA 4XROA 4LQWC 1GWPA 1E6JP 4DGAC 1M9YC 1EIAA 3H4EA 4U0DA 1AK4C 2XGYA 2PXRC 2Y4ZA 4U0AA 3NTEA 2KGFA 2WLVA 4QNBA 1P7NA 4PH3A 2EIAA 4XFXA 1D1DA 2X2DD 4B4NA 2X82A 4U0BA 1M9FC 4PH0A 2GONA 2WLVB 1M9DC 3BP9A 4J93A 1M9EC 2XGVA 5HGKA 2X83A 5HGOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1EM9 A;  1G03 A;  4WYM A;  2XDE A;  1M9C C;  5HGM A;  4U0F A;  5JPA A;  4NX4 C;  4HTW A;  4E91 A;  2LF4 A;  4PH2 A;  2M8N A;  4XRQ A;  4E92 A;  5HGL A;  2V4X A;  3H47 A;  4U0E A;  4XFZ A;  3MGE A;  4INB A;  1U7K A;  2JPR A;  4U0C A;  2GOL B;  1M9X C;  2PWM A;  2PWO A;  1L6N A;  2M8P A;  2XGU A;  4XFY A;  5HGN A;  3P05 A;  1QRJ A;  4DGE C;  2M8L A;  1AFV A;  4XRO A;  4LQW C;  1GWP A;  1E6J P;  4DGA C;  1M9Y C;  1EIA A;  3H4E A;  4U0D A;  1AK4 C;  2XGY A;  2PXR C;  2Y4Z A;  4U0A A;  3NTE A;  2KGF A;  2WLV A;  4QNB A;  1P7N A;  4PH3 A;  2EIA A;  4XFX A;  1D1D A;  2X2D D;  4B4N A;  2X82 A;  4U0B A;  1M9F C;  4PH0 A;  2GON A;  2WLV B;  1M9D C;  3BP9 A;  4J93 A;  1M9E C;  2XGV A;  5HGK A;  2X83 A;  5HGO A; 
#chains in the Genus database with same CATH topology
 1EM9 A;  1G03 A;  4WYM A;  2XDE A;  1M9C C;  5HGM A;  4U0F A;  5JPA A;  4NX4 C;  4HTW A;  4E91 A;  2LF4 A;  4PH2 A;  2M8N A;  4XRQ A;  4E92 A;  5HGL A;  2V4X A;  3H47 A;  4U0E A;  4XFZ A;  3MGE A;  4INB A;  1U7K A;  2JPR A;  4U0C A;  2GOL B;  1M9X C;  2PWM A;  2PWO A;  1L6N A;  2M8P A;  2XGU A;  4XFY A;  5HGN A;  3P05 A;  1QRJ A;  4DGE C;  2M8L A;  1AFV A;  4XRO A;  4LQW C;  1GWP A;  1E6J P;  4DGA C;  1M9Y C;  1EIA A;  3H4E A;  4U0D A;  1AK4 C;  2XGY A;  2PXR C;  2Y4Z A;  4U0A A;  3NTE A;  2KGF A;  2WLV A;  4QNB A;  1P7N A;  4PH3 A;  2EIA A;  4XFX A;  1D1D A;  2X2D D;  4B4N A;  2X82 A;  4U0B A;  1M9F C;  4PH0 A;  2GON A;  2WLV B;  1M9D C;  3BP9 A;  4J93 A;  1M9E C;  2XGV A;  5HGK A;  2X83 A;  5HGO A; 
#chains in the Genus database with same CATH homology
 1EM9 A;  1G03 A;  4WYM A;  2XDE A;  1M9C C;  5HGM A;  4U0F A;  5JPA A;  4NX4 C;  4HTW A;  4E91 A;  2LF4 A;  4PH2 A;  2M8N A;  4XRQ A;  4E92 A;  5HGL A;  2V4X A;  3H47 A;  4U0E A;  4XFZ A;  3MGE A;  4INB A;  1U7K A;  2JPR A;  4U0C A;  2GOL B;  1M9X C;  2PWM A;  2PWO A;  1L6N A;  2M8P A;  2XGU A;  4XFY A;  5HGN A;  3P05 A;  1QRJ A;  4DGE C;  2M8L A;  1AFV A;  4XRO A;  4LQW C;  1GWP A;  1E6J P;  4DGA C;  1M9Y C;  1EIA A;  3H4E A;  4U0D A;  1AK4 C;  2XGY A;  2PXR C;  2Y4Z A;  4U0A A;  3NTE A;  2KGF A;  2WLV A;  4QNB A;  1P7N A;  4PH3 A;  2EIA A;  4XFX A;  1D1D A;  2X2D D;  4B4N A;  2X82 A;  4U0B A;  1M9F C;  4PH0 A;  2GON A;  2WLV B;  1M9D C;  3BP9 A;  4J93 A;  1M9E C;  2XGV A;  5HGK A;  2X83 A;  5HGO A; 
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similar chains in the pdb database (?% sequence similarity)

 
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