1ASTA

Structure of astacin and implications for activation of astacins and zinc-ligation of collagenases
Total Genus 68
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
68
sequence length
200
structure length
200
Chain Sequence
AAILGDEYLWSGGVIPYTFAGVSGADQSAILSGMQELEEKTCIRFVPRTTESDYVEIFTSGSGCWSYVGRISGAQQVSLQANGCVYHGTIIHELMHAIGFYHEHTRMDRDNYVTINYQNVDPSMTSNFDIDTYSRYVGEDYQYYSIMHYGKYSFSIQWGVLETIVPLQNGIDLTDPYDKAHMLQTDANQINNLYTNECSL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of astacin and implications for activation of astacins and zinc-ligation of collagenases.
pubmed doi rcsb
molecule tags Hydrolase(metalloproteinase)
source organism Astacus astacus
molecule keywords ASTACIN
total genus 68
structure length 200
sequence length 200
ec nomenclature ec 3.4.24.21: Astacin.
pdb deposition date 1993-04-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01400 Astacin Astacin (Peptidase family M12A)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 1astA00
4FVLA 4EFSA 1GKDA 1MMRA 1O0QA 1EB6A 4L6TA 2X3CA 1OMJA 2WO8A 3HYGA 1OM7A 3LJTA 2JIHA 4PKSA 4J4MA 3B2ZA 2WO9A 3LGPA 1FLSA 3EHXA 3DSLA 1IACA 4GQLA 4WKIA 5BOTA 2POJA 2SRTA 3HY9A 4L19A 3Q2HA 1D5JA 1Y8JA 1UMTA 2FV5A 1BM6A 1FBLA 4H76A 2USNA 4GF1A 4PKQA 2MLSA 3LJZA 2X3BA 1CGFA 2AIGP 1USNA 3WV2A 456CA 1BKCI 4L63A 2JT5A 2D1NA 3N2VA 3ZXHA 1OS9A 3VTGA 1XFXA 1GKCA 1RM8A 3I7IA 1CQRA 4JQGA 1BKCE 1BUVM 4I03A 2OW2A 2RJQA 1AF0A 5D7WA 3UVCA 3RTSA 4WF6A 2ERQA 4G9LA 3DL1A 1XFUA 2W0DA 2OW1A 2W14A 1ASTA 1Z3JA 2ERPA 1D7XA 1XFVA 3HDAP 2I47A 4XBHA 1YP1A 4PKRA 2OVXA 3LQ0A 4R3VA 3HBVP 1DMTA 3P1VA 1UTTA 3WV3A 2AYKA 1Y93A 3L0TA 3P24A 2OW9A 4H3XA 1IAEA 1ZTQA 3O64A 3TT4A 830CA 2OI0A 1Y0VA 2YIGA 3HB2P 1AYKA 1CK7A 3ZVSA 3EWJA 3SHIA 4JPAA 1GO7P 1FM1A 4H1QA 5I0LA 5CUHA 1C3IA 1I1IP 2A8HA 4PKTA 4GUYA 966CA 3EDGA 1HV5A 2MLRA 3EDIA 4H84A 3DPFA 3OHOA 1QJIA 2DDFA 3HDBA 2K9CA 1CAQA 3BA0A 1D8FA 1I76A 1QJJA 1KUGA 1JH1A 1PWQA 3F15A 1GE6A 1OM8A 4PKWA 2TCLA 1KUHA 1UTZA 3G42A 5D2BA 3LMCA 5JMYA 2OXZA 2OVZA 4H49A 2OZRA 3KMEA 1IAAA 2X3AA 3LKAA 4ON1A 2KRJA 3V96B 1SU3A 1CXVA 2CLTA 4FU4A 3K7NA 1YQYA 4AXQA 1IAGA 5I12A 4ZR5A 3KMCA 1SRPA 1JAOA 4GWMA 5BPAA 1YOUA 4DV8A 3AIGA 3LEAA 1J7NA 2RJPA 1SLMA 1G9KA 3USNA 1KAPP 4PKVA 1IADA 2OXUA 1BUDA 2Y6CA 4FXQA 2WOAA 1HFCA 3TS4A 1ZP5A 2CKIA 2DW0A 1GO8P 3N2UA 1EAKA 5L79A 4GR3A 2J83A 4XM6A 1ROSA 1R55A 1CGLA 2PJTA 5D1SA 3ELMA 1R1HA 1QIBA 4JIJA 3F1AA 1ATLA 2EROA 1KUKA 4A7BA 1R1IA 4GR8A 3B8ZA 1JAPA 3DNGA 1BKCA 1G12A 1XURA 2QPJA 1GXDA 1JKYA 4WK7A 1JIZA 1A86A 5CZMA 1PWUA 1KUFA 3G5CA 1JK3A 4H82A 4H30A 2Y6DA 2W15A 1JIWP 5H8XA 1PWWA 5I43A 3EHYA 4DF9A 1PWVA 1BQOA 1JAQA 1PWPA 3K7LA 1C7KA 1YCMA 1A85A 3OHLA 1BZSA 3LUNA 1QICA 2OY4A 2YB9A 1ZXCA 3LQBA 3F16A 4DPEA 2DW2A 5I2ZA 1Q3AA 3KEKA 3KRYA 5D1TA 5BOYA 4JP4A 3L0VA 4PKUA 3TVCA 5LABA 1IABA 5I3MA 1UEAA 2JT6A 3HBUP 1HFSA 4HX3A 1OO9A 2OXWA 3EDZA 1G4KA 4QKZA 5D1UA 1ND1A 1HOVA 1EUBA 1GE5A 1XFZA 1MMPA 1BSWA 1S4BP 5L7FA 1OS2A 1KUIA 1XFYA 1ZS0A 2DW1A 1MMBA 4A3WA 1BQQM 3HY7A 2L0RA 2XS4A 3DPEA 4IJOA 2DDYA 3LK8A 4DD8A 2D1OA 2W13A 4XM8A 4Q1LA 2MZEA 2OW0A 1I73A 3U1RA 3I7GA 3LUMA 3CKIA 1KBCA 1MNCA 4GR0A 1HY7A 4AUOA 1GE7A 4XCTA 3MA2A 4IUWA 1QIAA 3KEJA 5B5OA 1XUCA 3F17A 3TSKA 4JA1A 2MZHA 1XFWA 2JSDA 1K7GA 2K2GA 1XUDA 5CXAA 3KECA 1AKLA 1WNIA 3LILA 3F18A 3VI1A 4ILWD 3DWBA 4I35A 1RMZA 4GWNA 2E2DA 3GBOA 4IN9A 1O0TA 3AYUA 1G05A 2FV9A 5I4OA 3NX7A 2XS3A 1R1JA 1ZVXA 1R54A 4H2EA 1ZXVA 4FXYP 4CTHA 2MZIA 3LE9A 2J0TA 1BIWA 3E8RA 2JNPA 2HU6A 4HMAA 1D8MA 3LJGA 4G0DA 1QUAA 1DTHA 3ZUKA 2N8RA 2Z2DA 4XM7A 1K7QA 3WV1A 2O36A 3Q2GA 3KHIA 3EDHA 2O3EA 1L6JA 1UMSA 2E3XA 1B3DA 1JANA 1JJ9A 3LIRA 1SLNA 2W12A 1G49A 4AIGA 1SATA 3AYKA 2OY2A 3F19A 5B5PA 4WKEA 3KWVC 5D3CA 3LIKA 4AYKA 3B92A 3O2XA 1K7IA 2X7MA 1C8TA 1CGEA 1HTDA 1OM6A 1CIZA 1H71P 1B8YA 4WZVA 2V4BA 3RTTA 1MMQA 1SMPA
chains in the Genus database with same CATH superfamily
4FVLA 4EFSA 1GKDA 1MMRA 1O0QA 1EB6A 4L6TA 2X3CA 1OMJA 3DTEA 2WO8A 3HYGA 1OM7A 3LJTA 2JIHA 4PKSA 4J4MA 3B2ZA 2WO9A 3LGPA 1FLSA 3EHXA 3DSLA 1IACA 4GQLA 4WKIA 5BOTA 2POJA 2SRTA 3HY9A 4L19A 3Q2HA 1D5JA 1Y8JA 1UMTA 2FV5A 1BM6A 1FBLA 4H76A 2USNA 4GF1A 4PKQA 2MLSA 3LJZA 2X3BA 1CGFA 2AIGP 1USNA 3WV2A 456CA 1BKCI 4L63A 2JT5A 2D1NA 3N2VA 3ZXHA 1OS9A 3VTGA 1XFXA 1GKCA 1RM8A 3I7IA 1CQRA 4JQGA 1BKCE 1BUVM 4I03A 2OW2A 2RJQA 1AF0A 5D7WA 3UVCA 3RTSA 4WF6A 2ERQA 4G9LA 3DL1A 1XFUA 2W0DA 1TVIA 2OW1A 2W14A 1ASTA 1Z3JA 2ERPA 1D7XA 1XFVA 3HDAP 2I47A 4XBHA 1YP1A 4PKRA 3DTKA 2OVXA 3LQ0A 4R3VA 3HBVP 1DMTA 3P1VA 1UTTA 3WV3A 2AYKA 1Y93A 3L0TA 4L7AA 3P24A 2OW9A 4H3XA 1IAEA 1ZTQA 3O64A 3TT4A 830CA 2OI0A 1Y0VA 2YIGA 3HB2P 1AYKA 1CK7A 3ZVSA 3EWJA 3SHIA 4JPAA 1GO7P 1FM1A 4H1QA 5I0LA 5CUHA 1C3IA 1I1IP 2A8HA 4PKTA 4GUYA 966CA 3EDGA 1HV5A 2MLRA 3EDIA 4H84A 3DPFA 3OHOA 1QJIA 3DTIA 2DDFA 3HDBA 2K9CA 1CAQA 3BA0A 1D8FA 1I76A 1QJJA 1KUGA 1JH1A 1PWQA 3F15A 1GE6A 1OM8A 4PKWA 2TCLA 1KUHA 1UTZA 3G42A 5D2BA 3LMCA 5JMYA 2OXZA 2OVZA 4H49A 2OZRA 3KMEA 1IAAA 2X3AA 3LKAA 4ON1A 2KRJA 3V96B 1SU3A 1CXVA 2CLTA 4FU4A 3K7NA 1YQYA 4AXQA 1IAGA 1XAXA 5I12A 4ZR5A 3KMCA 1SRPA 1JAOA 4GWMA 5BPAA 1YOUA 4DV8A 3AIGA 3LEAA 1J7NA 2RJPA 1SLMA 1G9KA 3USNA 1KAPP 4PKVA 1IADA 2OXUA 1BUDA 2Y6CA 4FXQA 2WOAA 1HFCA 3TS4A 1ZP5A 2CKIA 2DW0A 1GO8P 3N2UA 1EAKA 5L79A 4GR3A 2J83A 4XM6A 1ROSA 1R55A 1CGLA 2PJTA 5D1SA 3ELMA 1R1HA 1QIBA 4JIJA 3F1AA 1ATLA 2EROA 1KUKA 4A7BA 1R1IA 4GR8A 3B8ZA 1JAPA 3DNGA 1BKCA 1G12A 1XURA 2QPJA 1GXDA 1JKYA 4WK7A 1JIZA 1A86A 5CZMA 1PWUA 1KUFA 3G5CA 1JK3A 4H82A 4H30A 2Y6DA 2W15A 1JIWP 5H8XA 1PWWA 5I43A 3EHYA 4DF9A 1PWVA 1BQOA 1JAQA 1PWPA 3K7LA 1C7KA 1YCMA 1A85A 3OHLA 1BZSA 3LUNA 1QICA 2OY4A 2YB9A 1ZXCA 3LQBA 3F16A 4DPEA 2DW2A 5I2ZA 1Q3AA 3KEKA 3KRYA 1XM5A 5D1TA 5BOYA 4JP4A 3L0VA 4PKUA 3TVCA 5LABA 1IABA 5I3MA 1UEAA 2JT6A 3HBUP 1HFSA 4HX3A 1OO9A 2OXWA 3EDZA 1G4KA 4QKZA 5D1UA 1ND1A 1HOVA 1EUBA 1GE5A 1XFZA 1MMPA 1BSWA 1S4BP 5L7FA 1OS2A 1KUIA 1XFYA 1ZS0A 2DW1A 1MMBA 4A3WA 1BQQM 3HY7A 2L0RA 2XS4A 3DPEA 4IJOA 2DDYA 3LK8A 4DD8A 2D1OA 2W13A 4XM8A 4Q1LA 2MZEA 2OW0A 1I73A 3U1RA 3I7GA 3LUMA 3CKIA 1KBCA 1MNCA 4GR0A 1HY7A 4AUOA 1GE7A 4XCTA 3MA2A 4IUWA 1QIAA 3KEJA 5B5OA 1XUCA 3F17A 3TSKA 4JA1A 2MZHA 1XFWA 2JSDA 1K7GA 2K2GA 1XUDA 5CXAA 3KECA 1AKLA 1WNIA 3LILA 3F18A 3VI1A 4ILWD 3DWBA 4I35A 1RMZA 4GWNA 2E2DA 3GBOA 4IN9A 1O0TA 3AYUA 1G05A 2FV9A 5I4OA 3NX7A 2XS3A 1R1JA 1ZVXA 1R54A 4H2EA 1ZXVA 4FXYP 4CTHA 2MZIA 3LE9A 2J0TA 1BIWA 3E8RA 1OZ9A 2JNPA 2HU6A 4HMAA 1D8MA 3LJGA 4G0DA 1QUAA 1DTHA 3ZUKA 2N8RA 2Z2DA 4XM7A 1K7QA 3WV1A 2O36A 3Q2GA 3KHIA 3EDHA 2O3EA 1L6JA 1UMSA 2E3XA 1B3DA 1JANA 1JJ9A 3LIRA 1SLNA 2W12A 1G49A 4AIGA 1SATA 3AYKA 2OY2A 3F19A 5B5PA 4WKEA 2YUFA 3KWVC 5D3CA 3LIKA 4AYKA 3B92A 3O2XA 1K7IA 2X7MA 1C8TA 1CGEA 1HTDA 1OM6A 1CIZA 1H71P 1B8YA 4WZVA 2V4BA 3RTTA 1MMQA 1SMPA
chains in the Genus database with same CATH topology
4FVLA 4EFSA 1GKDA 1MMRA 1O0QA 1EB6A 4L6TA 2X3CA 1OMJA 3DTEA 2WO8A 3HYGA 1OM7A 3LJTA 2JIHA 4PKSA 4J4MA 3B2ZA 2WO9A 3LGPA 1FLSA 3EHXA 3DSLA 1IACA 4GQLA 4WKIA 5BOTA 2POJA 2SRTA 3HY9A 4L19A 3Q2HA 1D5JA 1Y8JA 1UMTA 2FV5A 1BM6A 1FBLA 4H76A 2USNA 4GF1A 4PKQA 2MLSA 3LJZA 2X3BA 1CGFA 2AIGP 1USNA 3WV2A 456CA 1BKCI 4L63A 2JT5A 2D1NA 3N2VA 3ZXHA 1OS9A 3VTGA 1XFXA 1GKCA 1RM8A 3I7IA 1CQRA 4JQGA 1BKCE 1BUVM 4I03A 2OW2A 2RJQA 1AF0A 5D7WA 3UVCA 3RTSA 4WF6A 2ERQA 4G9LA 3DL1A 1XFUA 2W0DA 2OW1A 2W14A 1ASTA 1Z3JA 2ERPA 1D7XA 1XFVA 3HDAP 2I47A 4XBHA 1YP1A 4PKRA 3DTKA 2OVXA 3LQ0A 4R3VA 3HBVP 1DMTA 3P1VA 1UTTA 3WV3A 2AYKA 1Y93A 3L0TA 4L7AA 3P24A 2OW9A 4H3XA 1IAEA 1ZTQA 3O64A 3TT4A 830CA 2OI0A 1Y0VA 2YIGA 3HB2P 1AYKA 1CK7A 3ZVSA 3EWJA 3SHIA 4JPAA 1GO7P 1FM1A 4H1QA 5I0LA 5CUHA 1C3IA 1I1IP 2A8HA 4PKTA 4GUYA 966CA 3EDGA 1HV5A 2MLRA 3EDIA 4H84A 3DPFA 3OHOA 1QJIA 3DTIA 2DDFA 3HDBA 2K9CA 1CAQA 3BA0A 1D8FA 1I76A 1QJJA 1KUGA 1JH1A 1PWQA 3F15A 1GE6A 1OM8A 4PKWA 2TCLA 1KUHA 1UTZA 3G42A 5D2BA 3LMCA 5JMYA 2OXZA 2OVZA 4H49A 2OZRA 3KMEA 1IAAA 2X3AA 3LKAA 4ON1A 2KRJA 3V96B 1SU3A 1CXVA 2CLTA 4FU4A 3K7NA 1YQYA 4AXQA 1IAGA 5I12A 4ZR5A 3KMCA 1SRPA 1JAOA 4GWMA 5BPAA 1YOUA 4DV8A 3AIGA 3LEAA 1J7NA 2RJPA 1SLMA 1G9KA 3USNA 1KAPP 4PKVA 1IADA 2OXUA 1BUDA 2Y6CA 4FXQA 2WOAA 1HFCA 3TS4A 1ZP5A 2CKIA 2DW0A 1GO8P 3N2UA 1EAKA 5L79A 4GR3A 2J83A 4XM6A 1ROSA 1R55A 1CGLA 2PJTA 5D1SA 3ELMA 1R1HA 1QIBA 4JIJA 3F1AA 1ATLA 2EROA 1KUKA 4A7BA 1R1IA 4GR8A 3B8ZA 1JAPA 3DNGA 1BKCA 1G12A 1XURA 2QPJA 1GXDA 1JKYA 4WK7A 1JIZA 1A86A 5CZMA 1PWUA 1KUFA 3G5CA 1JK3A 4H82A 4H30A 2Y6DA 2W15A 1JIWP 5H8XA 1PWWA 5I43A 3EHYA 4DF9A 1PWVA 1BQOA 1JAQA 1PWPA 3K7LA 1C7KA 1YCMA 1A85A 3OHLA 1BZSA 3LUNA 1QICA 2OY4A 2YB9A 1ZXCA 3LQBA 3F16A 4DPEA 2DW2A 5I2ZA 1Q3AA 3KEKA 3KRYA 5D1TA 5BOYA 4JP4A 3L0VA 4PKUA 3TVCA 5LABA 1IABA 5I3MA 1UEAA 2JT6A 3HBUP 1HFSA 4HX3A 1OO9A 2OXWA 3EDZA 1G4KA 4QKZA 5D1UA 1ND1A 1HOVA 1EUBA 1GE5A 1XFZA 1MMPA 1BSWA 1S4BP 5L7FA 1OS2A 1KUIA 1XFYA 1ZS0A 2DW1A 1MMBA 4A3WA 1BQQM 3HY7A 2L0RA 2XS4A 3DPEA 4IJOA 2DDYA 3LK8A 4DD8A 2D1OA 2W13A 4XM8A 4Q1LA 2MZEA 2OW0A 1I73A 3U1RA 3I7GA 3LUMA 3CKIA 1KBCA 1MNCA 4GR0A 1HY7A 4AUOA 1GE7A 4XCTA 3MA2A 4IUWA 1QIAA 3KEJA 5B5OA 1XUCA 3F17A 3TSKA 4JA1A 2MZHA 1XFWA 2JSDA 1K7GA 2K2GA 1XUDA 5CXAA 3KECA 1AKLA 1WNIA 3LILA 3F18A 3VI1A 4ILWD 3DWBA 4I35A 1RMZA 4GWNA 2E2DA 3GBOA 4IN9A 1O0TA 3AYUA 1G05A 2FV9A 5I4OA 3NX7A 2XS3A 1R1JA 1ZVXA 1R54A 4H2EA 1ZXVA 4FXYP 4CTHA 2MZIA 3LE9A 2J0TA 1BIWA 3E8RA 2JNPA 2HU6A 4HMAA 1D8MA 3LJGA 4G0DA 1QUAA 1DTHA 3ZUKA 2N8RA 2Z2DA 4XM7A 1K7QA 3WV1A 2O36A 3Q2GA 3KHIA 3EDHA 2O3EA 1L6JA 1UMSA 2E3XA 1B3DA 1JANA 1JJ9A 3LIRA 1SLNA 2W12A 1G49A 4AIGA 1SATA 3AYKA 2OY2A 3F19A 5B5PA 4WKEA 2YUFA 3KWVC 5D3CA 3LIKA 4AYKA 3B92A 3O2XA 1K7IA 2X7MA 1C8TA 1CGEA 1HTDA 1OM6A 1CIZA 1H71P 1B8YA 4WZVA 2V4BA 3RTTA 1MMQA 1SMPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4FVL A;  4EFS A;  1GKD A;  1MMR A;  1O0Q A;  1EB6 A;  4L6T A;  2X3C A;  1OMJ A;  2WO8 A;  3HYG A;  1OM7 A;  3LJT A;  2JIH A;  4PKS A;  4J4M A;  3B2Z A;  2WO9 A;  3LGP A;  1FLS A;  3EHX A;  3DSL A;  1IAC A;  4GQL A;  4WKI A;  5BOT A;  2POJ A;  2SRT A;  3HY9 A;  4L19 A;  3Q2H A;  1D5J A;  1Y8J A;  1UMT A;  2FV5 A;  1BM6 A;  1FBL A;  4H76 A;  2USN A;  4GF1 A;  4PKQ A;  2MLS A;  3LJZ A;  2X3B A;  1CGF A;  2AIG P;  1USN A;  3WV2 A;  456C A;  1BKC I;  4L63 A;  2JT5 A;  2D1N A;  3N2V A;  3ZXH A;  1OS9 A;  3VTG A;  1XFX A;  1GKC A;  1RM8 A;  3I7I A;  1CQR A;  4JQG A;  1BKC E;  1BUV M;  4I03 A;  2OW2 A;  2RJQ A;  1AF0 A;  5D7W A;  3UVC A;  3RTS A;  4WF6 A;  2ERQ A;  4G9L A;  3DL1 A;  1XFU A;  2W0D A;  2OW1 A;  2W14 A;  1AST A;  1Z3J A;  2ERP A;  1D7X A;  1XFV A;  3HDA P;  2I47 A;  4XBH A;  1YP1 A;  4PKR A;  2OVX A;  3LQ0 A;  4R3V A;  3HBV P;  1DMT A;  3P1V A;  1UTT A;  3WV3 A;  2AYK A;  1Y93 A;  3L0T A;  3P24 A;  2OW9 A;  4H3X A;  1IAE A;  1ZTQ A;  3O64 A;  3TT4 A;  830C A;  2OI0 A;  1Y0V A;  2YIG A;  3HB2 P;  1AYK A;  1CK7 A;  3ZVS A;  3EWJ A;  3SHI A;  4JPA A;  1GO7 P;  1FM1 A;  4H1Q A;  5I0L A;  5CUH A;  1C3I A;  1I1I P;  2A8H A;  4PKT A;  4GUY A;  966C A;  3EDG A;  1HV5 A;  2MLR A;  3EDI A;  4H84 A;  3DPF A;  3OHO A;  1QJI A;  2DDF A;  3HDB A;  2K9C A;  1CAQ A;  3BA0 A;  1D8F A;  1I76 A;  1QJJ A;  1KUG A;  1JH1 A;  1PWQ A;  3F15 A;  1GE6 A;  1OM8 A;  4PKW A;  2TCL A;  1KUH A;  1UTZ A;  3G42 A;  5D2B A;  3LMC A;  5JMY A;  2OXZ A;  2OVZ A;  4H49 A;  2OZR A;  3KME A;  1IAA A;  2X3A A;  3LKA A;  4ON1 A;  2KRJ A;  3V96 B;  1SU3 A;  1CXV A;  2CLT A;  4FU4 A;  3K7N A;  1YQY A;  4AXQ A;  1IAG A;  5I12 A;  4ZR5 A;  3KMC A;  1SRP A;  1JAO A;  4GWM A;  5BPA A;  1YOU A;  4DV8 A;  3AIG A;  3LEA A;  1J7N A;  2RJP A;  1SLM A;  1G9K A;  3USN A;  1KAP P;  4PKV A;  1IAD A;  2OXU A;  1BUD A;  2Y6C A;  4FXQ A;  2WOA A;  1HFC A;  3TS4 A;  1ZP5 A;  2CKI A;  2DW0 A;  1GO8 P;  3N2U A;  1EAK A;  5L79 A;  4GR3 A;  2J83 A;  4XM6 A;  1ROS A;  1R55 A;  1CGL A;  2PJT A;  5D1S A;  3ELM A;  1R1H A;  1QIB A;  4JIJ A;  3F1A A;  1ATL A;  2ERO A;  1KUK A;  4A7B A;  1R1I A;  4GR8 A;  3B8Z A;  1JAP A;  3DNG A;  1BKC A;  1G12 A;  1XUR A;  2QPJ A;  1GXD A;  1JKY A;  4WK7 A;  1JIZ A;  1A86 A;  5CZM A;  1PWU A;  1KUF A;  3G5C A;  1JK3 A;  4H82 A;  4H30 A;  2Y6D A;  2W15 A;  1JIW P;  5H8X A;  1PWW A;  5I43 A;  3EHY A;  4DF9 A;  1PWV A;  1BQO A;  1JAQ A;  1PWP A;  3K7L A;  1C7K A;  1YCM A;  1A85 A;  3OHL A;  1BZS A;  3LUN A;  1QIC A;  2OY4 A;  2YB9 A;  1ZXC A;  3LQB A;  3F16 A;  4DPE A;  2DW2 A;  5I2Z A;  1Q3A A;  3KEK A;  3KRY A;  5D1T A;  5BOY A;  4JP4 A;  3L0V A;  4PKU A;  3TVC A;  5LAB A;  1IAB A;  5I3M A;  1UEA A;  2JT6 A;  3HBU P;  1HFS A;  4HX3 A;  1OO9 A;  2OXW A;  3EDZ A;  1G4K A;  4QKZ A;  5D1U A;  1ND1 A;  1HOV A;  1EUB A;  1GE5 A;  1XFZ A;  1MMP A;  1BSW A;  1S4B P;  5L7F A;  1OS2 A;  1KUI A;  1XFY A;  1ZS0 A;  2DW1 A;  1MMB A;  4A3W A;  1BQQ M;  3HY7 A;  2L0R A;  2XS4 A;  3DPE A;  4IJO A;  2DDY A;  3LK8 A;  4DD8 A;  2D1O A;  2W13 A;  4XM8 A;  4Q1L A;  2MZE A;  2OW0 A;  1I73 A;  3U1R A;  3I7G A;  3LUM A;  3CKI A;  1KBC A;  1MNC A;  4GR0 A;  1HY7 A;  4AUO A;  1GE7 A;  4XCT A;  3MA2 A;  4IUW A;  1QIA A;  3KEJ A;  5B5O A;  1XUC A;  3F17 A;  3TSK A;  4JA1 A;  2MZH A;  1XFW A;  2JSD A;  1K7G A;  2K2G A;  1XUD A;  5CXA A;  3KEC A;  1AKL A;  1WNI A;  3LIL A;  3F18 A;  3VI1 A;  4ILW D;  3DWB A;  4I35 A;  1RMZ A;  4GWN A;  2E2D A;  3GBO A;  4IN9 A;  1O0T A;  3AYU A;  1G05 A;  2FV9 A;  5I4O A;  3NX7 A;  2XS3 A;  1R1J A;  1ZVX A;  1R54 A;  4H2E A;  1ZXV A;  4FXY P;  4CTH A;  2MZI A;  3LE9 A;  2J0T A;  1BIW A;  3E8R A;  2JNP A;  2HU6 A;  4HMA A;  1D8M A;  3LJG A;  4G0D A;  1QUA A;  1DTH A;  3ZUK A;  2N8R A;  2Z2D A;  4XM7 A;  1K7Q A;  3WV1 A;  2O36 A;  3Q2G A;  3KHI A;  3EDH A;  2O3E A;  1L6J A;  1UMS A;  2E3X A;  1B3D A;  1JAN A;  1JJ9 A;  3LIR A;  1SLN A;  2W12 A;  1G49 A;  4AIG A;  1SAT A;  3AYK A;  2OY2 A;  3F19 A;  5B5P A;  4WKE A;  3KWV C;  5D3C A;  3LIK A;  4AYK A;  3B92 A;  3O2X A;  1K7I A;  2X7M A;  1C8T A;  1CGE A;  1HTD A;  1OM6 A;  1CIZ A;  1H71 P;  1B8Y A;  4WZV A;  2V4B A;  3RTT A;  1MMQ A;  1SMP A; 
#chains in the Genus database with same CATH topology
 4FVL A;  4EFS A;  1GKD A;  1MMR A;  1O0Q A;  1EB6 A;  4L6T A;  2X3C A;  1OMJ A;  3DTE A;  2WO8 A;  3HYG A;  1OM7 A;  3LJT A;  2JIH A;  4PKS A;  4J4M A;  3B2Z A;  2WO9 A;  3LGP A;  1FLS A;  3EHX A;  3DSL A;  1IAC A;  4GQL A;  4WKI A;  5BOT A;  2POJ A;  2SRT A;  3HY9 A;  4L19 A;  3Q2H A;  1D5J A;  1Y8J A;  1UMT A;  2FV5 A;  1BM6 A;  1FBL A;  4H76 A;  2USN A;  4GF1 A;  4PKQ A;  2MLS A;  3LJZ A;  2X3B A;  1CGF A;  2AIG P;  1USN A;  3WV2 A;  456C A;  1BKC I;  4L63 A;  2JT5 A;  2D1N A;  3N2V A;  3ZXH A;  1OS9 A;  3VTG A;  1XFX A;  1GKC A;  1RM8 A;  3I7I A;  1CQR A;  4JQG A;  1BKC E;  1BUV M;  4I03 A;  2OW2 A;  2RJQ A;  1AF0 A;  5D7W A;  3UVC A;  3RTS A;  4WF6 A;  2ERQ A;  4G9L A;  3DL1 A;  1XFU A;  2W0D A;  1TVI A;  2OW1 A;  2W14 A;  1AST A;  1Z3J A;  2ERP A;  1D7X A;  1XFV A;  3HDA P;  2I47 A;  4XBH A;  1YP1 A;  4PKR A;  3DTK A;  2OVX A;  3LQ0 A;  4R3V A;  3HBV P;  1DMT A;  3P1V A;  1UTT A;  3WV3 A;  2AYK A;  1Y93 A;  3L0T A;  4L7A A;  3P24 A;  2OW9 A;  4H3X A;  1IAE A;  1ZTQ A;  3O64 A;  3TT4 A;  830C A;  2OI0 A;  1Y0V A;  2YIG A;  3HB2 P;  1AYK A;  1CK7 A;  3ZVS A;  3EWJ A;  3SHI A;  4JPA A;  1GO7 P;  1FM1 A;  4H1Q A;  5I0L A;  5CUH A;  1C3I A;  1I1I P;  2A8H A;  4PKT A;  4GUY A;  966C A;  3EDG A;  1HV5 A;  2MLR A;  3EDI A;  4H84 A;  3DPF A;  3OHO A;  1QJI A;  3DTI A;  2DDF A;  3HDB A;  2K9C A;  1CAQ A;  3BA0 A;  1D8F A;  1I76 A;  1QJJ A;  1KUG A;  1JH1 A;  1PWQ A;  3F15 A;  1GE6 A;  1OM8 A;  4PKW A;  2TCL A;  1KUH A;  1UTZ A;  3G42 A;  5D2B A;  3LMC A;  5JMY A;  2OXZ A;  2OVZ A;  4H49 A;  2OZR A;  3KME A;  1IAA A;  2X3A A;  3LKA A;  4ON1 A;  2KRJ A;  3V96 B;  1SU3 A;  1CXV A;  2CLT A;  4FU4 A;  3K7N A;  1YQY A;  4AXQ A;  1IAG A;  1XAX A;  5I12 A;  4ZR5 A;  3KMC A;  1SRP A;  1JAO A;  4GWM A;  5BPA A;  1YOU A;  4DV8 A;  3AIG A;  3LEA A;  1J7N A;  2RJP A;  1SLM A;  1G9K A;  3USN A;  1KAP P;  4PKV A;  1IAD A;  2OXU A;  1BUD A;  2Y6C A;  4FXQ A;  2WOA A;  1HFC A;  3TS4 A;  1ZP5 A;  2CKI A;  2DW0 A;  1GO8 P;  3N2U A;  1EAK A;  5L79 A;  4GR3 A;  2J83 A;  4XM6 A;  1ROS A;  1R55 A;  1CGL A;  2PJT A;  5D1S A;  3ELM A;  1R1H A;  1QIB A;  4JIJ A;  3F1A A;  1ATL A;  2ERO A;  1KUK A;  4A7B A;  1R1I A;  4GR8 A;  3B8Z A;  1JAP A;  3DNG A;  1BKC A;  1G12 A;  1XUR A;  2QPJ A;  1GXD A;  1JKY A;  4WK7 A;  1JIZ A;  1A86 A;  5CZM A;  1PWU A;  1KUF A;  3G5C A;  1JK3 A;  4H82 A;  4H30 A;  2Y6D A;  2W15 A;  1JIW P;  5H8X A;  1PWW A;  5I43 A;  3EHY A;  4DF9 A;  1PWV A;  1BQO A;  1JAQ A;  1PWP A;  3K7L A;  1C7K A;  1YCM A;  1A85 A;  3OHL A;  1BZS A;  3LUN A;  1QIC A;  2OY4 A;  2YB9 A;  1ZXC A;  3LQB A;  3F16 A;  4DPE A;  2DW2 A;  5I2Z A;  1Q3A A;  3KEK A;  3KRY A;  1XM5 A;  5D1T A;  5BOY A;  4JP4 A;  3L0V A;  4PKU A;  3TVC A;  5LAB A;  1IAB A;  5I3M A;  1UEA A;  2JT6 A;  3HBU P;  1HFS A;  4HX3 A;  1OO9 A;  2OXW A;  3EDZ A;  1G4K A;  4QKZ A;  5D1U A;  1ND1 A;  1HOV A;  1EUB A;  1GE5 A;  1XFZ A;  1MMP A;  1BSW A;  1S4B P;  5L7F A;  1OS2 A;  1KUI A;  1XFY A;  1ZS0 A;  2DW1 A;  1MMB A;  4A3W A;  1BQQ M;  3HY7 A;  2L0R A;  2XS4 A;  3DPE A;  4IJO A;  2DDY A;  3LK8 A;  4DD8 A;  2D1O A;  2W13 A;  4XM8 A;  4Q1L A;  2MZE A;  2OW0 A;  1I73 A;  3U1R A;  3I7G A;  3LUM A;  3CKI A;  1KBC A;  1MNC A;  4GR0 A;  1HY7 A;  4AUO A;  1GE7 A;  4XCT A;  3MA2 A;  4IUW A;  1QIA A;  3KEJ A;  5B5O A;  1XUC A;  3F17 A;  3TSK A;  4JA1 A;  2MZH A;  1XFW A;  2JSD A;  1K7G A;  2K2G A;  1XUD A;  5CXA A;  3KEC A;  1AKL A;  1WNI A;  3LIL A;  3F18 A;  3VI1 A;  4ILW D;  3DWB A;  4I35 A;  1RMZ A;  4GWN A;  2E2D A;  3GBO A;  4IN9 A;  1O0T A;  3AYU A;  1G05 A;  2FV9 A;  5I4O A;  3NX7 A;  2XS3 A;  1R1J A;  1ZVX A;  1R54 A;  4H2E A;  1ZXV A;  4FXY P;  4CTH A;  2MZI A;  3LE9 A;  2J0T A;  1BIW A;  3E8R A;  1OZ9 A;  2JNP A;  2HU6 A;  4HMA A;  1D8M A;  3LJG A;  4G0D A;  1QUA A;  1DTH A;  3ZUK A;  2N8R A;  2Z2D A;  4XM7 A;  1K7Q A;  3WV1 A;  2O36 A;  3Q2G A;  3KHI A;  3EDH A;  2O3E A;  1L6J A;  1UMS A;  2E3X A;  1B3D A;  1JAN A;  1JJ9 A;  3LIR A;  1SLN A;  2W12 A;  1G49 A;  4AIG A;  1SAT A;  3AYK A;  2OY2 A;  3F19 A;  5B5P A;  4WKE A;  2YUF A;  3KWV C;  5D3C A;  3LIK A;  4AYK A;  3B92 A;  3O2X A;  1K7I A;  2X7M A;  1C8T A;  1CGE A;  1HTD A;  1OM6 A;  1CIZ A;  1H71 P;  1B8Y A;  4WZV A;  2V4B A;  3RTT A;  1MMQ A;  1SMP A; 
#chains in the Genus database with same CATH homology
 4FVL A;  4EFS A;  1GKD A;  1MMR A;  1O0Q A;  1EB6 A;  4L6T A;  2X3C A;  1OMJ A;  3DTE A;  2WO8 A;  3HYG A;  1OM7 A;  3LJT A;  2JIH A;  4PKS A;  4J4M A;  3B2Z A;  2WO9 A;  3LGP A;  1FLS A;  3EHX A;  3DSL A;  1IAC A;  4GQL A;  4WKI A;  5BOT A;  2POJ A;  2SRT A;  3HY9 A;  4L19 A;  3Q2H A;  1D5J A;  1Y8J A;  1UMT A;  2FV5 A;  1BM6 A;  1FBL A;  4H76 A;  2USN A;  4GF1 A;  4PKQ A;  2MLS A;  3LJZ A;  2X3B A;  1CGF A;  2AIG P;  1USN A;  3WV2 A;  456C A;  1BKC I;  4L63 A;  2JT5 A;  2D1N A;  3N2V A;  3ZXH A;  1OS9 A;  3VTG A;  1XFX A;  1GKC A;  1RM8 A;  3I7I A;  1CQR A;  4JQG A;  1BKC E;  1BUV M;  4I03 A;  2OW2 A;  2RJQ A;  1AF0 A;  5D7W A;  3UVC A;  3RTS A;  4WF6 A;  2ERQ A;  4G9L A;  3DL1 A;  1XFU A;  2W0D A;  2OW1 A;  2W14 A;  1AST A;  1Z3J A;  2ERP A;  1D7X A;  1XFV A;  3HDA P;  2I47 A;  4XBH A;  1YP1 A;  4PKR A;  3DTK A;  2OVX A;  3LQ0 A;  4R3V A;  3HBV P;  1DMT A;  3P1V A;  1UTT A;  3WV3 A;  2AYK A;  1Y93 A;  3L0T A;  4L7A A;  3P24 A;  2OW9 A;  4H3X A;  1IAE A;  1ZTQ A;  3O64 A;  3TT4 A;  830C A;  2OI0 A;  1Y0V A;  2YIG A;  3HB2 P;  1AYK A;  1CK7 A;  3ZVS A;  3EWJ A;  3SHI A;  4JPA A;  1GO7 P;  1FM1 A;  4H1Q A;  5I0L A;  5CUH A;  1C3I A;  1I1I P;  2A8H A;  4PKT A;  4GUY A;  966C A;  3EDG A;  1HV5 A;  2MLR A;  3EDI A;  4H84 A;  3DPF A;  3OHO A;  1QJI A;  3DTI A;  2DDF A;  3HDB A;  2K9C A;  1CAQ A;  3BA0 A;  1D8F A;  1I76 A;  1QJJ A;  1KUG A;  1JH1 A;  1PWQ A;  3F15 A;  1GE6 A;  1OM8 A;  4PKW A;  2TCL A;  1KUH A;  1UTZ A;  3G42 A;  5D2B A;  3LMC A;  5JMY A;  2OXZ A;  2OVZ A;  4H49 A;  2OZR A;  3KME A;  1IAA A;  2X3A A;  3LKA A;  4ON1 A;  2KRJ A;  3V96 B;  1SU3 A;  1CXV A;  2CLT A;  4FU4 A;  3K7N A;  1YQY A;  4AXQ A;  1IAG A;  5I12 A;  4ZR5 A;  3KMC A;  1SRP A;  1JAO A;  4GWM A;  5BPA A;  1YOU A;  4DV8 A;  3AIG A;  3LEA A;  1J7N A;  2RJP A;  1SLM A;  1G9K A;  3USN A;  1KAP P;  4PKV A;  1IAD A;  2OXU A;  1BUD A;  2Y6C A;  4FXQ A;  2WOA A;  1HFC A;  3TS4 A;  1ZP5 A;  2CKI A;  2DW0 A;  1GO8 P;  3N2U A;  1EAK A;  5L79 A;  4GR3 A;  2J83 A;  4XM6 A;  1ROS A;  1R55 A;  1CGL A;  2PJT A;  5D1S A;  3ELM A;  1R1H A;  1QIB A;  4JIJ A;  3F1A A;  1ATL A;  2ERO A;  1KUK A;  4A7B A;  1R1I A;  4GR8 A;  3B8Z A;  1JAP A;  3DNG A;  1BKC A;  1G12 A;  1XUR A;  2QPJ A;  1GXD A;  1JKY A;  4WK7 A;  1JIZ A;  1A86 A;  5CZM A;  1PWU A;  1KUF A;  3G5C A;  1JK3 A;  4H82 A;  4H30 A;  2Y6D A;  2W15 A;  1JIW P;  5H8X A;  1PWW A;  5I43 A;  3EHY A;  4DF9 A;  1PWV A;  1BQO A;  1JAQ A;  1PWP A;  3K7L A;  1C7K A;  1YCM A;  1A85 A;  3OHL A;  1BZS A;  3LUN A;  1QIC A;  2OY4 A;  2YB9 A;  1ZXC A;  3LQB A;  3F16 A;  4DPE A;  2DW2 A;  5I2Z A;  1Q3A A;  3KEK A;  3KRY A;  5D1T A;  5BOY A;  4JP4 A;  3L0V A;  4PKU A;  3TVC A;  5LAB A;  1IAB A;  5I3M A;  1UEA A;  2JT6 A;  3HBU P;  1HFS A;  4HX3 A;  1OO9 A;  2OXW A;  3EDZ A;  1G4K A;  4QKZ A;  5D1U A;  1ND1 A;  1HOV A;  1EUB A;  1GE5 A;  1XFZ A;  1MMP A;  1BSW A;  1S4B P;  5L7F A;  1OS2 A;  1KUI A;  1XFY A;  1ZS0 A;  2DW1 A;  1MMB A;  4A3W A;  1BQQ M;  3HY7 A;  2L0R A;  2XS4 A;  3DPE A;  4IJO A;  2DDY A;  3LK8 A;  4DD8 A;  2D1O A;  2W13 A;  4XM8 A;  4Q1L A;  2MZE A;  2OW0 A;  1I73 A;  3U1R A;  3I7G A;  3LUM A;  3CKI A;  1KBC A;  1MNC A;  4GR0 A;  1HY7 A;  4AUO A;  1GE7 A;  4XCT A;  3MA2 A;  4IUW A;  1QIA A;  3KEJ A;  5B5O A;  1XUC A;  3F17 A;  3TSK A;  4JA1 A;  2MZH A;  1XFW A;  2JSD A;  1K7G A;  2K2G A;  1XUD A;  5CXA A;  3KEC A;  1AKL A;  1WNI A;  3LIL A;  3F18 A;  3VI1 A;  4ILW D;  3DWB A;  4I35 A;  1RMZ A;  4GWN A;  2E2D A;  3GBO A;  4IN9 A;  1O0T A;  3AYU A;  1G05 A;  2FV9 A;  5I4O A;  3NX7 A;  2XS3 A;  1R1J A;  1ZVX A;  1R54 A;  4H2E A;  1ZXV A;  4FXY P;  4CTH A;  2MZI A;  3LE9 A;  2J0T A;  1BIW A;  3E8R A;  2JNP A;  2HU6 A;  4HMA A;  1D8M A;  3LJG A;  4G0D A;  1QUA A;  1DTH A;  3ZUK A;  2N8R A;  2Z2D A;  4XM7 A;  1K7Q A;  3WV1 A;  2O36 A;  3Q2G A;  3KHI A;  3EDH A;  2O3E A;  1L6J A;  1UMS A;  2E3X A;  1B3D A;  1JAN A;  1JJ9 A;  3LIR A;  1SLN A;  2W12 A;  1G49 A;  4AIG A;  1SAT A;  3AYK A;  2OY2 A;  3F19 A;  5B5P A;  4WKE A;  2YUF A;  3KWV C;  5D3C A;  3LIK A;  4AYK A;  3B92 A;  3O2X A;  1K7I A;  2X7M A;  1C8T A;  1CGE A;  1HTD A;  1OM6 A;  1CIZ A;  1H71 P;  1B8Y A;  4WZV A;  2V4B A;  3RTT A;  1MMQ A;  1SMP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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