1BHTA

Nk1 fragment of human hepatocyte growth factor
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
176
structure length
176
Chain Sequence
RRNTIHEFKKSAKTTLIKIDPALKIKTKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the NK1 fragment of human hepatocyte growth factor at 2.0 A resolution.
pubmed doi rcsb
molecule tags Heparin-binding domain
source organism Homo sapiens
molecule keywords HEPATOCYTE GROWTH FACTOR
total genus 45
structure length 176
sequence length 176
chains with identical sequence B
ec nomenclature
pdb deposition date 1998-06-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00024 PAN_1 PAN domain
A PF00051 Kringle Kringle domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.20.10 Mainly Beta Beta Barrel Plasminogen Kringle 4 Plasminogen Kringle 4 1bhtA02
3.50.4.10 Alpha Beta 3-Layer(bba) Sandwich Hepatocyte Growth Factor Hepatocyte Growth Factor 1bhtA01
4BV5A 2HGFA 3HMSA 2Q8BA 2K4RA 2PF1A 1JFNA 2I9AA 4Z0FA 2PF2A 2LL4M 5EOKA 1GMOA 4Z09A 1Z40A 2F83A 3KIVA 2QJ4A 4R1BA 2HPPP 1PK4A 2FEBA 2DOIA 1KDUA 4UAOA 2SPTA 4BVVA 4O03A 1NL2A 1CEBA 2Y8RA 3U73A 5HPGA 1HKYA 3LAQA 5CS1A 3E6PL 4UV6A 1NL1A 1TPKA 4A5TS 2Q8AA 1PMLA 2Z8WA 5CT2A 1PMKA 4KIVA 5CS3A 2X2ZA 4Z0DA 5EODA 4APMA 3ZWZA 1PKRA 2HPQP 3NXPA 1CEAA 2Z8VA 1BHTA 1I71A 4BVDA 2DOHX 4HZHA 1YXEA 3MKPA 2K13X 4APLA 5I25A 1NK1A 2L0SA 4CIKA 3SP8A 3SRJA 2I9BA 2FD6A 4D3CA 1PK2A 3HMRA 4BV7A 1I8NA 1KRNA 3ZLEA 4NZQA 5COEA 1GP9A 4IUAA 1W8KA 5CP9A 2YILA 3BT1A 1HPJA 2K51A 5CT1A 1A0HA 2KNFA 4R1CA 4BVCA 5CSQA 1KI0A 2YIPA 4R19A 2YIOA 4Z0EA 3HN4A 5CS9A 1W81A 3K65A 5CT3A 4DURA 3BT2A 1KIVA 4BVWA 2LL3A 3SRIA 1URKA 3HMTA 1HPKA 5CS5A 4R1AA 1B2IA 2J8JA 2QJ2A 1I5KA 2J8LA 1GMNA 2KJ4A 2PK4A
chains in the Genus database with same CATH superfamily
4BV5A 2HGFA 3HMSA 2Q8BA 2K4RA 2PF1A 1JFNA 2I9AA 4Z0FA 2PF2A 2LL4M 5EOKA 1GMOA 4Z09A 1Z40A 2F83A 3KIVA 2QJ4A 4R1BA 2HPPP 1PK4A 2FEBA 4YIZA 2DOIA 1KDUA 4UAOA 2SPTA 4BVVA 4O03A 1NL2A 1CEBA 2Y8RA 3U73A 5HPGA 1HKYA 3LAQA 5CS1A 3E6PL 4UV6A 1NL1A 1TPKA 4A5TS 2Q8AA 1PMLA 2Z8WA 5CT2A 1PMKA 4KIVA 5CS3A 2X2ZA 4Z0DA 5EODA 4APMA 3ZWZA 1PKRA 2HPQP 3NXPA 1CEAA 2Z8VA 1BHTA 1I71A 4BVDA 2DOHX 4HZHA 1YXEA 3MKPA 2K13X 4APLA 5I25A 1NK1A 2L0SA 4CIKA 3SP8A 3SRJA 2I9BA 2FD6A 4D3CA 1PK2A 3HMRA 4BV7A 1I8NA 1KRNA 3ZLEA 4NZQA 5COEA 1GP9A 4IUAA 1W8KA 5CP9A 2YILA 3BT1A 1HPJA 2K51A 5CT1A 1A0HA 2KNFA 4R1CA 4BVCA 5CSQA 1KI0A 2YIPA 4R19A 2YIOA 4Z0EA 3HN4A 5CS9A 1W81A 3K65A 5CT3A 2KL5A 4DURA 3BT2A 1KIVA 4BVWA 2LL3A 3SRIA 1URKA 3HMTA 1HPKA 5CS5A 4R1AA 1B2IA 2J8JA 2QJ2A 1I5KA 2J8LA 1GMNA 2KJ4A 4YIVA 2PK4A
chains in the Genus database with same CATH topology
4BV5A 2HGFA 3HMSA 2Q8BA 2K4RA 2PF1A 1JFNA 2I9AA 4Z0FA 2PF2A 2LL4M 5EOKA 1GMOA 4Z09A 1Z40A 2F83A 3KIVA 2QJ4A 4R1BA 2HPPP 1PK4A 2FEBA 4YIZA 2DOIA 1KDUA 4UAOA 2SPTA 4BVVA 4O03A 1NL2A 1CEBA 2Y8RA 3U73A 5HPGA 1HKYA 3LAQA 5CS1A 3E6PL 4UV6A 1NL1A 1TPKA 4A5TS 2Q8AA 1PMLA 2Z8WA 5CT2A 1PMKA 4KIVA 5CS3A 2X2ZA 4Z0DA 5EODA 4APMA 3ZWZA 1PKRA 2HPQP 3NXPA 1CEAA 2Z8VA 1BHTA 1I71A 4BVDA 2DOHX 4HZHA 1YXEA 3MKPA 2K13X 4APLA 5I25A 1NK1A 2L0SA 4CIKA 3SP8A 3SRJA 2I9BA 2FD6A 4D3CA 1PK2A 3HMRA 4BV7A 1I8NA 1KRNA 3ZLEA 4NZQA 5COEA 1GP9A 4IUAA 1W8KA 5CP9A 2YILA 3BT1A 1HPJA 2K51A 5CT1A 1A0HA 2KNFA 4R1CA 4BVCA 5CSQA 1KI0A 2YIPA 4R19A 2YIOA 4Z0EA 3HN4A 5CS9A 1W81A 3K65A 5CT3A 2KL5A 4DURA 3BT2A 1KIVA 4BVWA 2LL3A 3SRIA 1URKA 3HMTA 1HPKA 5CS5A 4R1AA 1B2IA 2J8JA 2QJ2A 1I5KA 2J8LA 1GMNA 2KJ4A 4YIVA 2PK4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4BV5 A;  2HGF A;  3HMS A;  2Q8B A;  2K4R A;  2PF1 A;  1JFN A;  2I9A A;  4Z0F A;  2PF2 A;  2LL4 M;  5EOK A;  1GMO A;  4Z09 A;  1Z40 A;  2F83 A;  3KIV A;  2QJ4 A;  4R1B A;  2HPP P;  1PK4 A;  2FEB A;  2DOI A;  1KDU A;  4UAO A;  2SPT A;  4BVV A;  4O03 A;  1NL2 A;  1CEB A;  2Y8R A;  3U73 A;  5HPG A;  1HKY A;  3LAQ A;  5CS1 A;  3E6P L;  4UV6 A;  1NL1 A;  1TPK A;  4A5T S;  2Q8A A;  1PML A;  2Z8W A;  5CT2 A;  1PMK A;  4KIV A;  5CS3 A;  2X2Z A;  4Z0D A;  5EOD A;  4APM A;  3ZWZ A;  1PKR A;  2HPQ P;  3NXP A;  1CEA A;  2Z8V A;  1BHT A;  1I71 A;  4BVD A;  2DOH X;  4HZH A;  1YXE A;  3MKP A;  2K13 X;  4APL A;  5I25 A;  1NK1 A;  2L0S A;  4CIK A;  3SP8 A;  3SRJ A;  2I9B A;  2FD6 A;  4D3C A;  1PK2 A;  3HMR A;  4BV7 A;  1I8N A;  1KRN A;  3ZLE A;  4NZQ A;  5COE A;  1GP9 A;  4IUA A;  1W8K A;  5CP9 A;  2YIL A;  3BT1 A;  1HPJ A;  2K51 A;  5CT1 A;  1A0H A;  2KNF A;  4R1C A;  4BVC A;  5CSQ A;  1KI0 A;  2YIP A;  4R19 A;  2YIO A;  4Z0E A;  3HN4 A;  5CS9 A;  1W81 A;  3K65 A;  5CT3 A;  4DUR A;  3BT2 A;  1KIV A;  4BVW A;  2LL3 A;  3SRI A;  1URK A;  3HMT A;  1HPK A;  5CS5 A;  4R1A A;  1B2I A;  2J8J A;  2QJ2 A;  1I5K A;  2J8L A;  1GMN A;  2KJ4 A;  2PK4 A; 
#chains in the Genus database with same CATH topology
 4BV5 A;  2HGF A;  3HMS A;  2Q8B A;  2K4R A;  2PF1 A;  1JFN A;  2I9A A;  4Z0F A;  2PF2 A;  2LL4 M;  5EOK A;  1GMO A;  4Z09 A;  1Z40 A;  2F83 A;  3KIV A;  2QJ4 A;  4R1B A;  2HPP P;  1PK4 A;  2FEB A;  4YIZ A;  2DOI A;  1KDU A;  4UAO A;  2SPT A;  4BVV A;  4O03 A;  1NL2 A;  1CEB A;  2Y8R A;  3U73 A;  5HPG A;  1HKY A;  3LAQ A;  5CS1 A;  3E6P L;  4UV6 A;  1NL1 A;  1TPK A;  4A5T S;  2Q8A A;  1PML A;  2Z8W A;  5CT2 A;  1PMK A;  4KIV A;  5CS3 A;  2X2Z A;  4Z0D A;  5EOD A;  4APM A;  3ZWZ A;  1PKR A;  2HPQ P;  3NXP A;  1CEA A;  2Z8V A;  1BHT A;  1I71 A;  4BVD A;  2DOH X;  4HZH A;  1YXE A;  3MKP A;  2K13 X;  4APL A;  5I25 A;  1NK1 A;  2L0S A;  4CIK A;  3SP8 A;  3SRJ A;  2I9B A;  2FD6 A;  4D3C A;  1PK2 A;  3HMR A;  4BV7 A;  1I8N A;  1KRN A;  3ZLE A;  4NZQ A;  5COE A;  1GP9 A;  4IUA A;  1W8K A;  5CP9 A;  2YIL A;  3BT1 A;  1HPJ A;  2K51 A;  5CT1 A;  1A0H A;  2KNF A;  4R1C A;  4BVC A;  5CSQ A;  1KI0 A;  2YIP A;  4R19 A;  2YIO A;  4Z0E A;  3HN4 A;  5CS9 A;  1W81 A;  3K65 A;  5CT3 A;  2KL5 A;  4DUR A;  3BT2 A;  1KIV A;  4BVW A;  2LL3 A;  3SRI A;  1URK A;  3HMT A;  1HPK A;  5CS5 A;  4R1A A;  1B2I A;  2J8J A;  2QJ2 A;  1I5K A;  2J8L A;  1GMN A;  2KJ4 A;  4YIV A;  2PK4 A; 
#chains in the Genus database with same CATH homology
 4BV5 A;  2HGF A;  3HMS A;  2Q8B A;  2K4R A;  2PF1 A;  1JFN A;  2I9A A;  4Z0F A;  2PF2 A;  2LL4 M;  5EOK A;  1GMO A;  4Z09 A;  1Z40 A;  2F83 A;  3KIV A;  2QJ4 A;  4R1B A;  2HPP P;  1PK4 A;  2FEB A;  4YIZ A;  2DOI A;  1KDU A;  4UAO A;  2SPT A;  4BVV A;  4O03 A;  1NL2 A;  1CEB A;  2Y8R A;  3U73 A;  5HPG A;  1HKY A;  3LAQ A;  5CS1 A;  3E6P L;  4UV6 A;  1NL1 A;  1TPK A;  4A5T S;  2Q8A A;  1PML A;  2Z8W A;  5CT2 A;  1PMK A;  4KIV A;  5CS3 A;  2X2Z A;  4Z0D A;  5EOD A;  4APM A;  3ZWZ A;  1PKR A;  2HPQ P;  3NXP A;  1CEA A;  2Z8V A;  1BHT A;  1I71 A;  4BVD A;  2DOH X;  4HZH A;  1YXE A;  3MKP A;  2K13 X;  4APL A;  5I25 A;  1NK1 A;  2L0S A;  4CIK A;  3SP8 A;  3SRJ A;  2I9B A;  2FD6 A;  4D3C A;  1PK2 A;  3HMR A;  4BV7 A;  1I8N A;  1KRN A;  3ZLE A;  4NZQ A;  5COE A;  1GP9 A;  4IUA A;  1W8K A;  5CP9 A;  2YIL A;  3BT1 A;  1HPJ A;  2K51 A;  5CT1 A;  1A0H A;  2KNF A;  4R1C A;  4BVC A;  5CSQ A;  1KI0 A;  2YIP A;  4R19 A;  2YIO A;  4Z0E A;  3HN4 A;  5CS9 A;  1W81 A;  3K65 A;  5CT3 A;  2KL5 A;  4DUR A;  3BT2 A;  1KIV A;  4BVW A;  2LL3 A;  3SRI A;  1URK A;  3HMT A;  1HPK A;  5CS5 A;  4R1A A;  1B2I A;  2J8J A;  2QJ2 A;  1I5K A;  2J8L A;  1GMN A;  2KJ4 A;  4YIV A;  2PK4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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