1BKCI

Catalytic domain of tnf-alpha converting enzyme (tace)
Total Genus 80
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
80
sequence length
254
structure length
254
Chain Sequence
MKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEEQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the catalytic domain of human tumor necrosis factor-alpha-converting enzyme.
pubmed doi rcsb
molecule tags Zn-endopeptidase
source organism Homo sapiens
molecule keywords TUMOR NECROSIS FACTOR-ALPHA-CONVERTING ENZYME
total genus 80
structure length 254
sequence length 254
ec nomenclature ec 3.4.24.86: ADAM 17 endopeptidase.
pdb deposition date 1998-04-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
I PF13688 Reprolysin_5 Metallo-peptidase family M12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 1bkcI00
5B5OA 1UTZA 5BPAA 3HB2P 2YB9A 4WK7A 1KUIA 1ND1A 2POJA 5I4OA 1KUKA 1C7KA 3LEAA 1B8YA 5CXAA 1PWQA 1G9KA 3E8RA 1BQOA 2JT6A 2RJQA 2MLSA 2OW9A 5BOTA 3LQBA 3BA0A 3HBVP 4A3WA 4GF1A 4AUOA 3HDBA 4GWMA 3LUMA 2FV9A 4GR8A 1IAEA 1I76A 1BZSA 1OS9A 4XM6A 3LMCA 3EDIA 2SRTA 1JH1A 4FXQA 2W12A 1YP1A 2O36A 1SLMA 4L19A 3U1RA 1JIZA 5D1TA 3DPEA 2W14A 1EB6A 5D2BA 1MMRA 3DL1A 2HU6A 4PKVA 5CZMA 1UMSA 1XFYA 3VI1A 3F15A 3F17A 5I43A 1QIBA 1R1JA 3EDZA 1CIZA 3KMEA 2DDFA 4GWNA 1BUDA 1S4BP 1IAGA 2KRJA 4FXYP 4FU4A 2JSDA 1G12A 3VTGA 1CGFA 1A85A 1B3DA 4J4MA 1OS2A 1Q3AA 966CA 1QICA 1CK7A 3F18A 4JP4A 1C3IA 5L79A 1BKCA 2X7MA 3P24A 3WV1A 1UTTA 3F19A 2E2DA 4XM8A 4CTHA 1MMBA 5D1UA 4H84A 4H3XA 3KECA 4HMAA 1CGEA 2K9CA 2FV5A 1ROSA 3LIRA 456CA 3LIKA 2X3CA 3B92A 1QJIA 3TVCA 4AYKA 1C8TA 2USNA 2YIGA 4JIJA 4DPEA 1WNIA 1ATLA 1JAOA 1L6JA 1D8FA 2JT5A 3N2VA 4Q1LA 1XUCA 1R54A 4I03A 1OM8A 2OVXA 1OM6A 1R1HA 4FVLA 3DNGA 1AKLA 2D1NA 5I3MA 1FLSA 1GE6A 4XM7A 1GO7P 4I35A 1ASTA 2MZHA 3ZXHA 3DSLA 2L0RA 4DD8A 1IAAA 3EDHA 1FM1A 3OHLA 2J83A 1HFSA 2E3XA 3L0TA 3OHOA 1G4KA 4ZR5A 3UVCA 3EDGA 1QIAA 3K7LA 4L63A 2XS4A 2WO9A 3F1AA 1HOVA 1KUHA 1JK3A 1XFZA 1Y0VA 4IUWA 4JA1A 4H49A 2I47A 830CA 5D3CA 1KUFA 4PKSA 1R55A 1ZVXA 1HTDA 1O0QA 1XFVA 3LJTA 3G5CA 1I1IP 2O3EA 2WO8A 2OY4A 1OM7A 1USNA 1MNCA 4G9LA 2OXZA 3EHYA 3KMCA 3O64A 1CXVA 3GBOA 1GXDA 1ZS0A 1HFCA 1JJ9A 1CQRA 3B8ZA 2AYKA 1QJJA 3LQ0A 4H30A 2X3BA 3HY9A 4GR3A 1IABA 3KEKA 3ELMA 2W0DA 1CAQA 4H2EA 3LGPA 2OW0A 2OXUA 5CUHA 3AYKA 4DF9A 3DPFA 3KRYA 2ERQA 3DWBA 2OI0A 1BM6A 1K7IA 3I7GA 4AXQA 3LE9A 4GUYA 3NX7A 1BKCE 3KHIA 1Y8JA 1J7NA 4EFSA 4PKQA 1IACA 2D1OA 4ILWD 2CKIA 4QKZA 5I12A 1D7XA 4H76A 1DMTA 2OW1A 1YOUA 2AIGP 2JNPA 1O0TA 4A7BA 1Y93A 1ZP5A 2OVZA 5I0LA 2V4BA 1GE5A 1R1IA 2W15A 1XFUA 3O2XA 1ZXCA 3G42A 1KBCA 3HY7A 4WF6A 5I2ZA 2X3AA 1KAPP 1RM8A 1ZTQA 2TCLA 4XCTA 3HDAP 3LK8A 4GQLA 1OMJA 3LUNA 1G49A 3WV2A 1PWPA 2MZIA 1SLNA 1BSWA 4ON1A 3LJGA 4R3VA 2MZEA 3LILA 3TS4A 1BIWA 1YCMA 2Z2DA 3P1VA 3B2ZA 5B5PA 1K7GA 1RMZA 1MMQA 5H8XA 4PKUA 4PKRA 2W13A 1PWUA 3AIGA 1QUAA 2OW2A 1DTHA 2QPJA 3EHXA 1GE7A 1KUGA 3EWJA 4JPAA 1D8MA 1G05A 1SRPA 1JIWP 1JAPA 2A8HA 4XBHA 1Z3JA 3F16A 1UEAA 1YQYA 4DV8A 3HBUP 2OZRA 1D5JA 2OXWA 2OY2A 4PKWA 3V96B 1BUVM 4IJOA 3KEJA 2WOAA 2K2GA 3AYUA 2XS3A 1BKCI 3Q2HA 2RJPA 5JMYA 3TT4A 3I7IA 1PWVA 3L0VA 2DW1A 2EROA 1JAQA 3LJZA 1FBLA 1GKCA 1PWWA 1XUDA 3ZUKA 2Y6DA 4H1QA 4WZVA 1XFXA 1HV5A 1UMTA 3N2UA 1ZXVA 3SHIA 1XURA 1I73A 4PKTA 1GO8P 1XFWA 5L7FA 4IN9A 1BQQM 1OO9A 1SMPA 1SATA 2ERPA 3RTTA 4WKIA 2Y6CA 1AF0A 5D7WA 5D1SA 2DW0A 1A86A 1GKDA 3CKIA 4L6TA 3TSKA 1IADA 5LABA 4AIGA 5BOYA 4HX3A 1EAKA 3K7NA 3WV3A 3ZVSA 4G0DA 2CLTA 1SU3A 2PJTA 1JANA 3LKAA 3RTSA 4GR0A 4H82A 1HY7A 4WKEA 4JQGA 1JKYA 1EUBA 2DW2A 2N8RA 3MA2A 1H71P 2JIHA 3USNA 1CGLA 1MMPA 1K7QA 2DDYA 3HYGA 1AYKA 2J0TA 3Q2GA 3KWVC 2MLRA
chains in the Genus database with same CATH superfamily
5B5OA 1UTZA 5BPAA 3HB2P 2YB9A 4WK7A 1KUIA 1ND1A 2POJA 5I4OA 1KUKA 1C7KA 3LEAA 1B8YA 5CXAA 1PWQA 1G9KA 3E8RA 1BQOA 2JT6A 2RJQA 2MLSA 2OW9A 5BOTA 3LQBA 3BA0A 3HBVP 4A3WA 4GF1A 4AUOA 3DTEA 3HDBA 4GWMA 3LUMA 2FV9A 4GR8A 1IAEA 1I76A 1BZSA 1OS9A 4XM6A 3LMCA 3EDIA 2SRTA 1JH1A 4FXQA 2W12A 1YP1A 2O36A 1SLMA 4L19A 3U1RA 1JIZA 5D1TA 3DPEA 2W14A 1EB6A 5D2BA 1MMRA 3DL1A 2HU6A 4PKVA 5CZMA 1UMSA 1XFYA 3VI1A 3F15A 3F17A 5I43A 1QIBA 1R1JA 3EDZA 1CIZA 3KMEA 3DTKA 2DDFA 4GWNA 1BUDA 1S4BP 1IAGA 2KRJA 4FXYP 4FU4A 2JSDA 1G12A 3VTGA 1CGFA 1A85A 1B3DA 4J4MA 1OS2A 1Q3AA 966CA 1QICA 1CK7A 3F18A 4JP4A 1C3IA 5L79A 1BKCA 2X7MA 3P24A 3WV1A 1UTTA 3F19A 1OZ9A 2E2DA 4XM8A 4CTHA 1MMBA 5D1UA 4H84A 4H3XA 3KECA 4HMAA 1CGEA 2K9CA 2FV5A 1ROSA 3LIRA 456CA 3LIKA 2X3CA 3B92A 1QJIA 3TVCA 4AYKA 1C8TA 2USNA 2YIGA 4JIJA 4DPEA 1WNIA 1ATLA 1JAOA 1L6JA 1D8FA 2JT5A 3N2VA 4Q1LA 1XUCA 1R54A 4I03A 1OM8A 2OVXA 1OM6A 1R1HA 4FVLA 3DNGA 1AKLA 2D1NA 5I3MA 1FLSA 1GE6A 4XM7A 1GO7P 4I35A 1ASTA 2MZHA 3ZXHA 3DSLA 2L0RA 4DD8A 1IAAA 3EDHA 1FM1A 3OHLA 2J83A 1HFSA 2E3XA 3L0TA 3OHOA 1G4KA 4ZR5A 3UVCA 3EDGA 1QIAA 3K7LA 4L63A 2XS4A 2WO9A 3F1AA 1HOVA 1KUHA 1JK3A 1XFZA 1Y0VA 4IUWA 4JA1A 4H49A 2I47A 830CA 5D3CA 1KUFA 4PKSA 1R55A 1ZVXA 1HTDA 1O0QA 1XFVA 3LJTA 3G5CA 1I1IP 2O3EA 2WO8A 2OY4A 1OM7A 1USNA 1MNCA 1XM5A 4G9LA 2OXZA 3EHYA 3KMCA 3O64A 1CXVA 3GBOA 1GXDA 1ZS0A 1HFCA 1JJ9A 1CQRA 3B8ZA 2AYKA 1QJJA 3LQ0A 4H30A 2X3BA 3HY9A 4GR3A 1IABA 3KEKA 3ELMA 2W0DA 1CAQA 4H2EA 3LGPA 2OW0A 2OXUA 5CUHA 3AYKA 4DF9A 3DPFA 3KRYA 2ERQA 3DWBA 2OI0A 1BM6A 1K7IA 3I7GA 4AXQA 3LE9A 4GUYA 3NX7A 1BKCE 3KHIA 1Y8JA 1J7NA 4EFSA 4PKQA 1IACA 2D1OA 4ILWD 2CKIA 4QKZA 5I12A 1D7XA 4H76A 1DMTA 2OW1A 1YOUA 2AIGP 3DTIA 2JNPA 1O0TA 4A7BA 1Y93A 1ZP5A 2OVZA 5I0LA 2V4BA 1GE5A 1R1IA 2W15A 1XFUA 3O2XA 1ZXCA 3G42A 1KBCA 3HY7A 4WF6A 5I2ZA 2X3AA 1KAPP 1RM8A 1ZTQA 2TCLA 4XCTA 3HDAP 3LK8A 4GQLA 1OMJA 3LUNA 1G49A 3WV2A 2YUFA 1PWPA 2MZIA 1SLNA 1TVIA 1BSWA 4ON1A 3LJGA 4R3VA 2MZEA 3LILA 3TS4A 1BIWA 1YCMA 2Z2DA 3P1VA 3B2ZA 5B5PA 1K7GA 1RMZA 1MMQA 5H8XA 4PKUA 4PKRA 2W13A 1PWUA 3AIGA 1QUAA 2OW2A 1DTHA 2QPJA 3EHXA 1GE7A 1KUGA 3EWJA 4JPAA 1D8MA 1G05A 1SRPA 1JIWP 1JAPA 2A8HA 4XBHA 1Z3JA 3F16A 1UEAA 1YQYA 4DV8A 3HBUP 2OZRA 1D5JA 2OXWA 2OY2A 4PKWA 3V96B 1BUVM 4IJOA 3KEJA 2WOAA 2K2GA 3AYUA 2XS3A 1BKCI 3Q2HA 2RJPA 5JMYA 3TT4A 3I7IA 1PWVA 3L0VA 2DW1A 2EROA 1JAQA 3LJZA 1FBLA 1GKCA 1PWWA 1XUDA 3ZUKA 2Y6DA 4H1QA 4WZVA 1XFXA 1HV5A 1UMTA 3N2UA 1ZXVA 3SHIA 1XURA 1XAXA 1I73A 4PKTA 1GO8P 1XFWA 5L7FA 4IN9A 1BQQM 1OO9A 1SMPA 1SATA 2ERPA 3RTTA 4WKIA 2Y6CA 1AF0A 5D7WA 5D1SA 2DW0A 1A86A 1GKDA 3CKIA 4L6TA 3TSKA 1IADA 5LABA 4AIGA 5BOYA 4HX3A 1EAKA 3K7NA 3WV3A 4L7AA 3ZVSA 4G0DA 2CLTA 1SU3A 2PJTA 1JANA 3LKAA 3RTSA 4GR0A 4H82A 1HY7A 4WKEA 4JQGA 1JKYA 1EUBA 2DW2A 2N8RA 3MA2A 1H71P 2JIHA 3USNA 1CGLA 1MMPA 1K7QA 2DDYA 3HYGA 1AYKA 2J0TA 3Q2GA 3KWVC 2MLRA
chains in the Genus database with same CATH topology
5B5OA 1UTZA 5BPAA 3HB2P 2YB9A 4WK7A 1KUIA 1ND1A 2POJA 5I4OA 1KUKA 1C7KA 3LEAA 1B8YA 5CXAA 1PWQA 1G9KA 3E8RA 1BQOA 2JT6A 2RJQA 2MLSA 2OW9A 5BOTA 3LQBA 3BA0A 3HBVP 4A3WA 4GF1A 4AUOA 3DTEA 3HDBA 4GWMA 3LUMA 2FV9A 4GR8A 1IAEA 1I76A 1BZSA 1OS9A 4XM6A 3LMCA 3EDIA 2SRTA 1JH1A 4FXQA 2W12A 1YP1A 2O36A 1SLMA 4L19A 3U1RA 1JIZA 5D1TA 3DPEA 2W14A 1EB6A 5D2BA 1MMRA 3DL1A 2HU6A 4PKVA 5CZMA 1UMSA 1XFYA 3VI1A 3F15A 3F17A 5I43A 1QIBA 1R1JA 3EDZA 1CIZA 3KMEA 3DTKA 2DDFA 4GWNA 1BUDA 1S4BP 1IAGA 2KRJA 4FXYP 4FU4A 2JSDA 1G12A 3VTGA 1CGFA 1A85A 1B3DA 4J4MA 1OS2A 1Q3AA 966CA 1QICA 1CK7A 3F18A 4JP4A 1C3IA 5L79A 1BKCA 2X7MA 3P24A 3WV1A 1UTTA 3F19A 2E2DA 4XM8A 4CTHA 1MMBA 5D1UA 4H84A 4H3XA 3KECA 4HMAA 1CGEA 2K9CA 2FV5A 1ROSA 3LIRA 456CA 3LIKA 2X3CA 3B92A 1QJIA 3TVCA 4AYKA 1C8TA 2USNA 2YIGA 4JIJA 4DPEA 1WNIA 1ATLA 1JAOA 1L6JA 1D8FA 2JT5A 3N2VA 4Q1LA 1XUCA 1R54A 4I03A 1OM8A 2OVXA 1OM6A 1R1HA 4FVLA 3DNGA 1AKLA 2D1NA 5I3MA 1FLSA 1GE6A 4XM7A 1GO7P 4I35A 1ASTA 2MZHA 3ZXHA 3DSLA 2L0RA 4DD8A 1IAAA 3EDHA 1FM1A 3OHLA 2J83A 1HFSA 2E3XA 3L0TA 3OHOA 1G4KA 4ZR5A 3UVCA 3EDGA 1QIAA 3K7LA 4L63A 2XS4A 2WO9A 3F1AA 1HOVA 1KUHA 1JK3A 1XFZA 1Y0VA 4IUWA 4JA1A 4H49A 2I47A 830CA 5D3CA 1KUFA 4PKSA 1R55A 1ZVXA 1HTDA 1O0QA 1XFVA 3LJTA 3G5CA 1I1IP 2O3EA 2WO8A 2OY4A 1OM7A 1USNA 1MNCA 4G9LA 2OXZA 3EHYA 3KMCA 3O64A 1CXVA 3GBOA 1GXDA 1ZS0A 1HFCA 1JJ9A 1CQRA 3B8ZA 2AYKA 1QJJA 3LQ0A 4H30A 2X3BA 3HY9A 4GR3A 1IABA 3KEKA 3ELMA 2W0DA 1CAQA 4H2EA 3LGPA 2OW0A 2OXUA 5CUHA 3AYKA 4DF9A 3DPFA 3KRYA 2ERQA 3DWBA 2OI0A 1BM6A 1K7IA 3I7GA 4AXQA 3LE9A 4GUYA 3NX7A 1BKCE 3KHIA 1Y8JA 1J7NA 4EFSA 4PKQA 1IACA 2D1OA 4ILWD 2CKIA 4QKZA 5I12A 1D7XA 4H76A 1DMTA 2OW1A 1YOUA 2AIGP 3DTIA 2JNPA 1O0TA 4A7BA 1Y93A 1ZP5A 2OVZA 5I0LA 2V4BA 1GE5A 1R1IA 2W15A 1XFUA 3O2XA 1ZXCA 3G42A 1KBCA 3HY7A 4WF6A 5I2ZA 2X3AA 1KAPP 1RM8A 1ZTQA 2TCLA 4XCTA 3HDAP 3LK8A 4GQLA 1OMJA 3LUNA 1G49A 3WV2A 2YUFA 1PWPA 2MZIA 1SLNA 1BSWA 4ON1A 3LJGA 4R3VA 2MZEA 3LILA 3TS4A 1BIWA 1YCMA 2Z2DA 3P1VA 3B2ZA 5B5PA 1K7GA 1RMZA 1MMQA 5H8XA 4PKUA 4PKRA 2W13A 1PWUA 3AIGA 1QUAA 2OW2A 1DTHA 2QPJA 3EHXA 1GE7A 1KUGA 3EWJA 4JPAA 1D8MA 1G05A 1SRPA 1JIWP 1JAPA 2A8HA 4XBHA 1Z3JA 3F16A 1UEAA 1YQYA 4DV8A 3HBUP 2OZRA 1D5JA 2OXWA 2OY2A 4PKWA 3V96B 1BUVM 4IJOA 3KEJA 2WOAA 2K2GA 3AYUA 2XS3A 1BKCI 3Q2HA 2RJPA 5JMYA 3TT4A 3I7IA 1PWVA 3L0VA 2DW1A 2EROA 1JAQA 3LJZA 1FBLA 1GKCA 1PWWA 1XUDA 3ZUKA 2Y6DA 4H1QA 4WZVA 1XFXA 1HV5A 1UMTA 3N2UA 1ZXVA 3SHIA 1XURA 1I73A 4PKTA 1GO8P 1XFWA 5L7FA 4IN9A 1BQQM 1OO9A 1SMPA 1SATA 2ERPA 3RTTA 4WKIA 2Y6CA 1AF0A 5D7WA 5D1SA 2DW0A 1A86A 1GKDA 3CKIA 4L6TA 3TSKA 1IADA 5LABA 4AIGA 5BOYA 4HX3A 1EAKA 3K7NA 3WV3A 4L7AA 3ZVSA 4G0DA 2CLTA 1SU3A 2PJTA 1JANA 3LKAA 3RTSA 4GR0A 4H82A 1HY7A 4WKEA 4JQGA 1JKYA 1EUBA 2DW2A 2N8RA 3MA2A 1H71P 2JIHA 3USNA 1CGLA 1MMPA 1K7QA 2DDYA 3HYGA 1AYKA 2J0TA 3Q2GA 3KWVC 2MLRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5B5O A;  1UTZ A;  5BPA A;  3HB2 P;  2YB9 A;  4WK7 A;  1KUI A;  1ND1 A;  2POJ A;  5I4O A;  1KUK A;  1C7K A;  3LEA A;  1B8Y A;  5CXA A;  1PWQ A;  1G9K A;  3E8R A;  1BQO A;  2JT6 A;  2RJQ A;  2MLS A;  2OW9 A;  5BOT A;  3LQB A;  3BA0 A;  3HBV P;  4A3W A;  4GF1 A;  4AUO A;  3HDB A;  4GWM A;  3LUM A;  2FV9 A;  4GR8 A;  1IAE A;  1I76 A;  1BZS A;  1OS9 A;  4XM6 A;  3LMC A;  3EDI A;  2SRT A;  1JH1 A;  4FXQ A;  2W12 A;  1YP1 A;  2O36 A;  1SLM A;  4L19 A;  3U1R A;  1JIZ A;  5D1T A;  3DPE A;  2W14 A;  1EB6 A;  5D2B A;  1MMR A;  3DL1 A;  2HU6 A;  4PKV A;  5CZM A;  1UMS A;  1XFY A;  3VI1 A;  3F15 A;  3F17 A;  5I43 A;  1QIB A;  1R1J A;  3EDZ A;  1CIZ A;  3KME A;  2DDF A;  4GWN A;  1BUD A;  1S4B P;  1IAG A;  2KRJ A;  4FXY P;  4FU4 A;  2JSD A;  1G12 A;  3VTG A;  1CGF A;  1A85 A;  1B3D A;  4J4M A;  1OS2 A;  1Q3A A;  966C A;  1QIC A;  1CK7 A;  3F18 A;  4JP4 A;  1C3I A;  5L79 A;  1BKC A;  2X7M A;  3P24 A;  3WV1 A;  1UTT A;  3F19 A;  2E2D A;  4XM8 A;  4CTH A;  1MMB A;  5D1U A;  4H84 A;  4H3X A;  3KEC A;  4HMA A;  1CGE A;  2K9C A;  2FV5 A;  1ROS A;  3LIR A;  456C A;  3LIK A;  2X3C A;  3B92 A;  1QJI A;  3TVC A;  4AYK A;  1C8T A;  2USN A;  2YIG A;  4JIJ A;  4DPE A;  1WNI A;  1ATL A;  1JAO A;  1L6J A;  1D8F A;  2JT5 A;  3N2V A;  4Q1L A;  1XUC A;  1R54 A;  4I03 A;  1OM8 A;  2OVX A;  1OM6 A;  1R1H A;  4FVL A;  3DNG A;  1AKL A;  2D1N A;  5I3M A;  1FLS A;  1GE6 A;  4XM7 A;  1GO7 P;  4I35 A;  1AST A;  2MZH A;  3ZXH A;  3DSL A;  2L0R A;  4DD8 A;  1IAA A;  3EDH A;  1FM1 A;  3OHL A;  2J83 A;  1HFS A;  2E3X A;  3L0T A;  3OHO A;  1G4K A;  4ZR5 A;  3UVC A;  3EDG A;  1QIA A;  3K7L A;  4L63 A;  2XS4 A;  2WO9 A;  3F1A A;  1HOV A;  1KUH A;  1JK3 A;  1XFZ A;  1Y0V A;  4IUW A;  4JA1 A;  4H49 A;  2I47 A;  830C A;  5D3C A;  1KUF A;  4PKS A;  1R55 A;  1ZVX A;  1HTD A;  1O0Q A;  1XFV A;  3LJT A;  3G5C A;  1I1I P;  2O3E A;  2WO8 A;  2OY4 A;  1OM7 A;  1USN A;  1MNC A;  4G9L A;  2OXZ A;  3EHY A;  3KMC A;  3O64 A;  1CXV A;  3GBO A;  1GXD A;  1ZS0 A;  1HFC A;  1JJ9 A;  1CQR A;  3B8Z A;  2AYK A;  1QJJ A;  3LQ0 A;  4H30 A;  2X3B A;  3HY9 A;  4GR3 A;  1IAB A;  3KEK A;  3ELM A;  2W0D A;  1CAQ A;  4H2E A;  3LGP A;  2OW0 A;  2OXU A;  5CUH A;  3AYK A;  4DF9 A;  3DPF A;  3KRY A;  2ERQ A;  3DWB A;  2OI0 A;  1BM6 A;  1K7I A;  3I7G A;  4AXQ A;  3LE9 A;  4GUY A;  3NX7 A;  1BKC E;  3KHI A;  1Y8J A;  1J7N A;  4EFS A;  4PKQ A;  1IAC A;  2D1O A;  4ILW D;  2CKI A;  4QKZ A;  5I12 A;  1D7X A;  4H76 A;  1DMT A;  2OW1 A;  1YOU A;  2AIG P;  2JNP A;  1O0T A;  4A7B A;  1Y93 A;  1ZP5 A;  2OVZ A;  5I0L A;  2V4B A;  1GE5 A;  1R1I A;  2W15 A;  1XFU A;  3O2X A;  1ZXC A;  3G42 A;  1KBC A;  3HY7 A;  4WF6 A;  5I2Z A;  2X3A A;  1KAP P;  1RM8 A;  1ZTQ A;  2TCL A;  4XCT A;  3HDA P;  3LK8 A;  4GQL A;  1OMJ A;  3LUN A;  1G49 A;  3WV2 A;  1PWP A;  2MZI A;  1SLN A;  1BSW A;  4ON1 A;  3LJG A;  4R3V A;  2MZE A;  3LIL A;  3TS4 A;  1BIW A;  1YCM A;  2Z2D A;  3P1V A;  3B2Z A;  5B5P A;  1K7G A;  1RMZ A;  1MMQ A;  5H8X A;  4PKU A;  4PKR A;  2W13 A;  1PWU A;  3AIG A;  1QUA A;  2OW2 A;  1DTH A;  2QPJ A;  3EHX A;  1GE7 A;  1KUG A;  3EWJ A;  4JPA A;  1D8M A;  1G05 A;  1SRP A;  1JIW P;  1JAP A;  2A8H A;  4XBH A;  1Z3J A;  3F16 A;  1UEA A;  1YQY A;  4DV8 A;  3HBU P;  2OZR A;  1D5J A;  2OXW A;  2OY2 A;  4PKW A;  3V96 B;  1BUV M;  4IJO A;  3KEJ A;  2WOA A;  2K2G A;  3AYU A;  2XS3 A;  1BKC I;  3Q2H A;  2RJP A;  5JMY A;  3TT4 A;  3I7I A;  1PWV A;  3L0V A;  2DW1 A;  2ERO A;  1JAQ A;  3LJZ A;  1FBL A;  1GKC A;  1PWW A;  1XUD A;  3ZUK A;  2Y6D A;  4H1Q A;  4WZV A;  1XFX A;  1HV5 A;  1UMT A;  3N2U A;  1ZXV A;  3SHI A;  1XUR A;  1I73 A;  4PKT A;  1GO8 P;  1XFW A;  5L7F A;  4IN9 A;  1BQQ M;  1OO9 A;  1SMP A;  1SAT A;  2ERP A;  3RTT A;  4WKI A;  2Y6C A;  1AF0 A;  5D7W A;  5D1S A;  2DW0 A;  1A86 A;  1GKD A;  3CKI A;  4L6T A;  3TSK A;  1IAD A;  5LAB A;  4AIG A;  5BOY A;  4HX3 A;  1EAK A;  3K7N A;  3WV3 A;  3ZVS A;  4G0D A;  2CLT A;  1SU3 A;  2PJT A;  1JAN A;  3LKA A;  3RTS A;  4GR0 A;  4H82 A;  1HY7 A;  4WKE A;  4JQG A;  1JKY A;  1EUB A;  2DW2 A;  2N8R A;  3MA2 A;  1H71 P;  2JIH A;  3USN A;  1CGL A;  1MMP A;  1K7Q A;  2DDY A;  3HYG A;  1AYK A;  2J0T A;  3Q2G A;  3KWV C;  2MLR A; 
#chains in the Genus database with same CATH topology
 5B5O A;  1UTZ A;  5BPA A;  3HB2 P;  2YB9 A;  4WK7 A;  1KUI A;  1ND1 A;  2POJ A;  5I4O A;  1KUK A;  1C7K A;  3LEA A;  1B8Y A;  5CXA A;  1PWQ A;  1G9K A;  3E8R A;  1BQO A;  2JT6 A;  2RJQ A;  2MLS A;  2OW9 A;  5BOT A;  3LQB A;  3BA0 A;  3HBV P;  4A3W A;  4GF1 A;  4AUO A;  3DTE A;  3HDB A;  4GWM A;  3LUM A;  2FV9 A;  4GR8 A;  1IAE A;  1I76 A;  1BZS A;  1OS9 A;  4XM6 A;  3LMC A;  3EDI A;  2SRT A;  1JH1 A;  4FXQ A;  2W12 A;  1YP1 A;  2O36 A;  1SLM A;  4L19 A;  3U1R A;  1JIZ A;  5D1T A;  3DPE A;  2W14 A;  1EB6 A;  5D2B A;  1MMR A;  3DL1 A;  2HU6 A;  4PKV A;  5CZM A;  1UMS A;  1XFY A;  3VI1 A;  3F15 A;  3F17 A;  5I43 A;  1QIB A;  1R1J A;  3EDZ A;  1CIZ A;  3KME A;  3DTK A;  2DDF A;  4GWN A;  1BUD A;  1S4B P;  1IAG A;  2KRJ A;  4FXY P;  4FU4 A;  2JSD A;  1G12 A;  3VTG A;  1CGF A;  1A85 A;  1B3D A;  4J4M A;  1OS2 A;  1Q3A A;  966C A;  1QIC A;  1CK7 A;  3F18 A;  4JP4 A;  1C3I A;  5L79 A;  1BKC A;  2X7M A;  3P24 A;  3WV1 A;  1UTT A;  3F19 A;  1OZ9 A;  2E2D A;  4XM8 A;  4CTH A;  1MMB A;  5D1U A;  4H84 A;  4H3X A;  3KEC A;  4HMA A;  1CGE A;  2K9C A;  2FV5 A;  1ROS A;  3LIR A;  456C A;  3LIK A;  2X3C A;  3B92 A;  1QJI A;  3TVC A;  4AYK A;  1C8T A;  2USN A;  2YIG A;  4JIJ A;  4DPE A;  1WNI A;  1ATL A;  1JAO A;  1L6J A;  1D8F A;  2JT5 A;  3N2V A;  4Q1L A;  1XUC A;  1R54 A;  4I03 A;  1OM8 A;  2OVX A;  1OM6 A;  1R1H A;  4FVL A;  3DNG A;  1AKL A;  2D1N A;  5I3M A;  1FLS A;  1GE6 A;  4XM7 A;  1GO7 P;  4I35 A;  1AST A;  2MZH A;  3ZXH A;  3DSL A;  2L0R A;  4DD8 A;  1IAA A;  3EDH A;  1FM1 A;  3OHL A;  2J83 A;  1HFS A;  2E3X A;  3L0T A;  3OHO A;  1G4K A;  4ZR5 A;  3UVC A;  3EDG A;  1QIA A;  3K7L A;  4L63 A;  2XS4 A;  2WO9 A;  3F1A A;  1HOV A;  1KUH A;  1JK3 A;  1XFZ A;  1Y0V A;  4IUW A;  4JA1 A;  4H49 A;  2I47 A;  830C A;  5D3C A;  1KUF A;  4PKS A;  1R55 A;  1ZVX A;  1HTD A;  1O0Q A;  1XFV A;  3LJT A;  3G5C A;  1I1I P;  2O3E A;  2WO8 A;  2OY4 A;  1OM7 A;  1USN A;  1MNC A;  1XM5 A;  4G9L A;  2OXZ A;  3EHY A;  3KMC A;  3O64 A;  1CXV A;  3GBO A;  1GXD A;  1ZS0 A;  1HFC A;  1JJ9 A;  1CQR A;  3B8Z A;  2AYK A;  1QJJ A;  3LQ0 A;  4H30 A;  2X3B A;  3HY9 A;  4GR3 A;  1IAB A;  3KEK A;  3ELM A;  2W0D A;  1CAQ A;  4H2E A;  3LGP A;  2OW0 A;  2OXU A;  5CUH A;  3AYK A;  4DF9 A;  3DPF A;  3KRY A;  2ERQ A;  3DWB A;  2OI0 A;  1BM6 A;  1K7I A;  3I7G A;  4AXQ A;  3LE9 A;  4GUY A;  3NX7 A;  1BKC E;  3KHI A;  1Y8J A;  1J7N A;  4EFS A;  4PKQ A;  1IAC A;  2D1O A;  4ILW D;  2CKI A;  4QKZ A;  5I12 A;  1D7X A;  4H76 A;  1DMT A;  2OW1 A;  1YOU A;  2AIG P;  3DTI A;  2JNP A;  1O0T A;  4A7B A;  1Y93 A;  1ZP5 A;  2OVZ A;  5I0L A;  2V4B A;  1GE5 A;  1R1I A;  2W15 A;  1XFU A;  3O2X A;  1ZXC A;  3G42 A;  1KBC A;  3HY7 A;  4WF6 A;  5I2Z A;  2X3A A;  1KAP P;  1RM8 A;  1ZTQ A;  2TCL A;  4XCT A;  3HDA P;  3LK8 A;  4GQL A;  1OMJ A;  3LUN A;  1G49 A;  3WV2 A;  2YUF A;  1PWP A;  2MZI A;  1SLN A;  1TVI A;  1BSW A;  4ON1 A;  3LJG A;  4R3V A;  2MZE A;  3LIL A;  3TS4 A;  1BIW A;  1YCM A;  2Z2D A;  3P1V A;  3B2Z A;  5B5P A;  1K7G A;  1RMZ A;  1MMQ A;  5H8X A;  4PKU A;  4PKR A;  2W13 A;  1PWU A;  3AIG A;  1QUA A;  2OW2 A;  1DTH A;  2QPJ A;  3EHX A;  1GE7 A;  1KUG A;  3EWJ A;  4JPA A;  1D8M A;  1G05 A;  1SRP A;  1JIW P;  1JAP A;  2A8H A;  4XBH A;  1Z3J A;  3F16 A;  1UEA A;  1YQY A;  4DV8 A;  3HBU P;  2OZR A;  1D5J A;  2OXW A;  2OY2 A;  4PKW A;  3V96 B;  1BUV M;  4IJO A;  3KEJ A;  2WOA A;  2K2G A;  3AYU A;  2XS3 A;  1BKC I;  3Q2H A;  2RJP A;  5JMY A;  3TT4 A;  3I7I A;  1PWV A;  3L0V A;  2DW1 A;  2ERO A;  1JAQ A;  3LJZ A;  1FBL A;  1GKC A;  1PWW A;  1XUD A;  3ZUK A;  2Y6D A;  4H1Q A;  4WZV A;  1XFX A;  1HV5 A;  1UMT A;  3N2U A;  1ZXV A;  3SHI A;  1XUR A;  1XAX A;  1I73 A;  4PKT A;  1GO8 P;  1XFW A;  5L7F A;  4IN9 A;  1BQQ M;  1OO9 A;  1SMP A;  1SAT A;  2ERP A;  3RTT A;  4WKI A;  2Y6C A;  1AF0 A;  5D7W A;  5D1S A;  2DW0 A;  1A86 A;  1GKD A;  3CKI A;  4L6T A;  3TSK A;  1IAD A;  5LAB A;  4AIG A;  5BOY A;  4HX3 A;  1EAK A;  3K7N A;  3WV3 A;  4L7A A;  3ZVS A;  4G0D A;  2CLT A;  1SU3 A;  2PJT A;  1JAN A;  3LKA A;  3RTS A;  4GR0 A;  4H82 A;  1HY7 A;  4WKE A;  4JQG A;  1JKY A;  1EUB A;  2DW2 A;  2N8R A;  3MA2 A;  1H71 P;  2JIH A;  3USN A;  1CGL A;  1MMP A;  1K7Q A;  2DDY A;  3HYG A;  1AYK A;  2J0T A;  3Q2G A;  3KWV C;  2MLR A; 
#chains in the Genus database with same CATH homology
 5B5O A;  1UTZ A;  5BPA A;  3HB2 P;  2YB9 A;  4WK7 A;  1KUI A;  1ND1 A;  2POJ A;  5I4O A;  1KUK A;  1C7K A;  3LEA A;  1B8Y A;  5CXA A;  1PWQ A;  1G9K A;  3E8R A;  1BQO A;  2JT6 A;  2RJQ A;  2MLS A;  2OW9 A;  5BOT A;  3LQB A;  3BA0 A;  3HBV P;  4A3W A;  4GF1 A;  4AUO A;  3DTE A;  3HDB A;  4GWM A;  3LUM A;  2FV9 A;  4GR8 A;  1IAE A;  1I76 A;  1BZS A;  1OS9 A;  4XM6 A;  3LMC A;  3EDI A;  2SRT A;  1JH1 A;  4FXQ A;  2W12 A;  1YP1 A;  2O36 A;  1SLM A;  4L19 A;  3U1R A;  1JIZ A;  5D1T A;  3DPE A;  2W14 A;  1EB6 A;  5D2B A;  1MMR A;  3DL1 A;  2HU6 A;  4PKV A;  5CZM A;  1UMS A;  1XFY A;  3VI1 A;  3F15 A;  3F17 A;  5I43 A;  1QIB A;  1R1J A;  3EDZ A;  1CIZ A;  3KME A;  3DTK A;  2DDF A;  4GWN A;  1BUD A;  1S4B P;  1IAG A;  2KRJ A;  4FXY P;  4FU4 A;  2JSD A;  1G12 A;  3VTG A;  1CGF A;  1A85 A;  1B3D A;  4J4M A;  1OS2 A;  1Q3A A;  966C A;  1QIC A;  1CK7 A;  3F18 A;  4JP4 A;  1C3I A;  5L79 A;  1BKC A;  2X7M A;  3P24 A;  3WV1 A;  1UTT A;  3F19 A;  2E2D A;  4XM8 A;  4CTH A;  1MMB A;  5D1U A;  4H84 A;  4H3X A;  3KEC A;  4HMA A;  1CGE A;  2K9C A;  2FV5 A;  1ROS A;  3LIR A;  456C A;  3LIK A;  2X3C A;  3B92 A;  1QJI A;  3TVC A;  4AYK A;  1C8T A;  2USN A;  2YIG A;  4JIJ A;  4DPE A;  1WNI A;  1ATL A;  1JAO A;  1L6J A;  1D8F A;  2JT5 A;  3N2V A;  4Q1L A;  1XUC A;  1R54 A;  4I03 A;  1OM8 A;  2OVX A;  1OM6 A;  1R1H A;  4FVL A;  3DNG A;  1AKL A;  2D1N A;  5I3M A;  1FLS A;  1GE6 A;  4XM7 A;  1GO7 P;  4I35 A;  1AST A;  2MZH A;  3ZXH A;  3DSL A;  2L0R A;  4DD8 A;  1IAA A;  3EDH A;  1FM1 A;  3OHL A;  2J83 A;  1HFS A;  2E3X A;  3L0T A;  3OHO A;  1G4K A;  4ZR5 A;  3UVC A;  3EDG A;  1QIA A;  3K7L A;  4L63 A;  2XS4 A;  2WO9 A;  3F1A A;  1HOV A;  1KUH A;  1JK3 A;  1XFZ A;  1Y0V A;  4IUW A;  4JA1 A;  4H49 A;  2I47 A;  830C A;  5D3C A;  1KUF A;  4PKS A;  1R55 A;  1ZVX A;  1HTD A;  1O0Q A;  1XFV A;  3LJT A;  3G5C A;  1I1I P;  2O3E A;  2WO8 A;  2OY4 A;  1OM7 A;  1USN A;  1MNC A;  4G9L A;  2OXZ A;  3EHY A;  3KMC A;  3O64 A;  1CXV A;  3GBO A;  1GXD A;  1ZS0 A;  1HFC A;  1JJ9 A;  1CQR A;  3B8Z A;  2AYK A;  1QJJ A;  3LQ0 A;  4H30 A;  2X3B A;  3HY9 A;  4GR3 A;  1IAB A;  3KEK A;  3ELM A;  2W0D A;  1CAQ A;  4H2E A;  3LGP A;  2OW0 A;  2OXU A;  5CUH A;  3AYK A;  4DF9 A;  3DPF A;  3KRY A;  2ERQ A;  3DWB A;  2OI0 A;  1BM6 A;  1K7I A;  3I7G A;  4AXQ A;  3LE9 A;  4GUY A;  3NX7 A;  1BKC E;  3KHI A;  1Y8J A;  1J7N A;  4EFS A;  4PKQ A;  1IAC A;  2D1O A;  4ILW D;  2CKI A;  4QKZ A;  5I12 A;  1D7X A;  4H76 A;  1DMT A;  2OW1 A;  1YOU A;  2AIG P;  3DTI A;  2JNP A;  1O0T A;  4A7B A;  1Y93 A;  1ZP5 A;  2OVZ A;  5I0L A;  2V4B A;  1GE5 A;  1R1I A;  2W15 A;  1XFU A;  3O2X A;  1ZXC A;  3G42 A;  1KBC A;  3HY7 A;  4WF6 A;  5I2Z A;  2X3A A;  1KAP P;  1RM8 A;  1ZTQ A;  2TCL A;  4XCT A;  3HDA P;  3LK8 A;  4GQL A;  1OMJ A;  3LUN A;  1G49 A;  3WV2 A;  2YUF A;  1PWP A;  2MZI A;  1SLN A;  1BSW A;  4ON1 A;  3LJG A;  4R3V A;  2MZE A;  3LIL A;  3TS4 A;  1BIW A;  1YCM A;  2Z2D A;  3P1V A;  3B2Z A;  5B5P A;  1K7G A;  1RMZ A;  1MMQ A;  5H8X A;  4PKU A;  4PKR A;  2W13 A;  1PWU A;  3AIG A;  1QUA A;  2OW2 A;  1DTH A;  2QPJ A;  3EHX A;  1GE7 A;  1KUG A;  3EWJ A;  4JPA A;  1D8M A;  1G05 A;  1SRP A;  1JIW P;  1JAP A;  2A8H A;  4XBH A;  1Z3J A;  3F16 A;  1UEA A;  1YQY A;  4DV8 A;  3HBU P;  2OZR A;  1D5J A;  2OXW A;  2OY2 A;  4PKW A;  3V96 B;  1BUV M;  4IJO A;  3KEJ A;  2WOA A;  2K2G A;  3AYU A;  2XS3 A;  1BKC I;  3Q2H A;  2RJP A;  5JMY A;  3TT4 A;  3I7I A;  1PWV A;  3L0V A;  2DW1 A;  2ERO A;  1JAQ A;  3LJZ A;  1FBL A;  1GKC A;  1PWW A;  1XUD A;  3ZUK A;  2Y6D A;  4H1Q A;  4WZV A;  1XFX A;  1HV5 A;  1UMT A;  3N2U A;  1ZXV A;  3SHI A;  1XUR A;  1I73 A;  4PKT A;  1GO8 P;  1XFW A;  5L7F A;  4IN9 A;  1BQQ M;  1OO9 A;  1SMP A;  1SAT A;  2ERP A;  3RTT A;  4WKI A;  2Y6C A;  1AF0 A;  5D7W A;  5D1S A;  2DW0 A;  1A86 A;  1GKD A;  3CKI A;  4L6T A;  3TSK A;  1IAD A;  5LAB A;  4AIG A;  5BOY A;  4HX3 A;  1EAK A;  3K7N A;  3WV3 A;  4L7A A;  3ZVS A;  4G0D A;  2CLT A;  1SU3 A;  2PJT A;  1JAN A;  3LKA A;  3RTS A;  4GR0 A;  4H82 A;  1HY7 A;  4WKE A;  4JQG A;  1JKY A;  1EUB A;  2DW2 A;  2N8R A;  3MA2 A;  1H71 P;  2JIH A;  3USN A;  1CGL A;  1MMP A;  1K7Q A;  2DDY A;  3HYG A;  1AYK A;  2J0T A;  3Q2G A;  3KWV C;  2MLR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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