1BKCI

Catalytic domain of tnf-alpha converting enzyme (tace)
Total Genus 80
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
80
sequence length
254
structure length
254
Chain Sequence
b'MKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEEQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERS'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords TUMOR NECROSIS FACTOR-ALPHA-CONVERTING ENZYME
publication title Crystal structure of the catalytic domain of human tumor necrosis factor-alpha-converting enzyme.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Zn-endopeptidase
total genus 80
structure length 254
sequence length 254
ec nomenclature ec 3.4.24.86: ADAM 17 endopeptidase.
pdb deposition date 1998-04-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
I PF13688 Reprolysin_5 Metallo-peptidase family M12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 1bkcI00
3RTSA 4H76A 1GKDA 1BKCI 2MZHA 3ZXHA 3TVCA 3LJGA 1KUGA 3DWBA 1PWUA 3I7GA 3UVCA 2E2DA 1JJ9A 2MLSA 1BUDA 4PKTA 3B92A 1QJJA 2O36A 1IABA 3I7IA 4PKQA 1I73A 5I0LA 4L6TA 2OW0A 1BKCA 1JIWP 4GR8A 3G5CA 1KUHA 1H71P 1S4BP 1XFWA 1XUDA 3EDGA 4CTHA 4EFSA 3EHYA 2POJA 1EAKA 1G49A 3KMEA 2QPJA 5D2BA 2JIHA 5B5OA 1CAQA 1D8FA 1XFVA 3HDBA 1FLSA 1RM8A 1XFUA 4PKUA 4J4MA 3KHIA 1SU3A 3KECA 4A3WA 1CQRA 1ND1A 3K7LA 3EDZA 4H49A 1PWWA 4JP4A 3F19A 3VTGA 3HY9A 3BA0A 2YIGA 2E3XA 2DDYA 4FU4A 1R55A 4L19A 4AIGA 3EDHA 1G4KA 2L0RA 4GUYA 5D3CA 3OHLA 3AYUA 1Q3AA 2D1NA 1UTZA 1GE7A 2W15A 2TCLA 2Y6DA 1FM1A 3LEAA 4JIJA 1ZTQA 2MZIA 3LIKA 1SATA 1ZS0A 4QKZA 1PWPA 4IUWA 2N8RA 2OXZA 3HBVP 2OVXA 2USNA 2DW2A 1ZXVA 3KEJA 1OM7A 1XFXA 1HTDA 4H82A 3EWJA 4JA1A 3TS4A 5I2ZA 5D1TA 4L63A 4AYKA 4WF6A 3DSLA 1XFZA 5CUHA 4ZR5A 1ZVXA 2Z2DA 1CGLA 1GO8P 3O2XA 4XM7A 4XM6A 2OY2A 2ERPA 2DW1A 1YP1A 1GKCA 4FXYP 3P1VA 1IACA 2WOAA 3WV3A 2YB9A 1CGFA 1ROSA 4FVLA 1ZXCA 1GXDA 2OW9A 3LJTA 3U1RA 2OXWA 1O0QA 2OW1A 1Y8JA 4G9LA 1Z3JA 4H3XA 1PWQA 4GWMA 1KUKA 1R54A 456CA 1HFSA 1SMPA 3ELMA 3LQBA 3NX7A 3L0TA 4H2EA 2OW2A 2OZRA 3WV1A 5JMYA 1HY7A 1K7GA 4HMAA 5I4OA 1USNA 1QICA 3HDAP 4PKVA 2KRJA 2WO8A 4AXQA 5I3MA 1O0TA 3DPFA 1KAPP 5L79A 2CLTA 3TT4A 3LUMA 1QJIA 1OO9A 3F1AA 3B2ZA 1KBCA 3B8ZA 3CKIA 1KUFA 1Y0VA 4JQGA 1B3DA 1JH1A 1BSWA 2W14A 4H1QA 1EB6A 1JAPA 1XUCA 3RTTA 3LUNA 4DF9A 1EUBA 1C8TA 1FBLA 4WK7A 966CA 1D5JA 2X3BA 3HB2P 2RJQA 2FV9A 1MNCA 4Q1LA 5LABA 4IN9A 1GE6A 1A85A 1JK3A 2JNPA 2OY4A 3DPEA 1RMZA 3LMCA 3Q2GA 3WV2A 1MMBA 3ZUKA 3GBOA 1CK7A 1PWVA 3N2UA 2W0DA 3LK8A 4JPAA 1SLMA 1C3IA 4GR3A 1D8MA 5I43A 1YQYA 5CZMA 1G9KA 5B5PA 1KUIA 1QIBA 4I03A 4XCTA 1L6JA 1JKYA 4GWNA 1ZP5A 1CXVA 1OS9A 3KWVC 3USNA 4XBHA 2EROA 1BUVM 2JT5A 3E8RA 5H8XA 4DD8A 1GO7P 4A7BA 3LKAA 4GF1A 3ZVSA 1SRPA 2OVZA 2W13A 5D1UA 1XURA 1YOUA 1XFYA 3O64A 4PKSA 1BZSA 3F17A 2CKIA 3OHOA 1QIAA 5BOYA 1CIZA 3VI1A 4DPEA 4WKEA 2X7MA 2A8HA 1Y93A 4AUOA 1J7NA 5BOTA 3AYKA 1JAQA 1BQOA 2ERQA 5D1SA 2OI0A 3HY7A 1BQQM 3F15A 5CXAA 4HX3A 1HOVA 2W12A 1HFCA 4ON1A 1I1IP 2XS3A 1IAGA 3L0VA 1JIZA 830CA 4GR0A 2XS4A 4H84A 2DDFA 3AIGA 4WKIA 4PKWA 2MLRA 3HYGA 1YCMA 1IAAA 2AIGP 4I35A 4WZVA 2HU6A 1CGEA 3Q2HA 2RJPA 2JT6A 3EHXA 1BIWA 1ASTA 5D7WA 2SRTA 1B8YA 1UEAA 4IJOA 1AYKA 2D1OA 4FXQA 2K9CA 1K7IA 3K7NA 1D7XA 2I47A 2J0TA 3LQ0A 4R3VA 5I12A 1AKLA 3HBUP 3N2VA 4PKRA 3LGPA 3LJZA 5L7FA 4ILWD 2PJTA 2FV5A 1JANA 1OMJA 1BKCE 1C7KA 1UTTA 3LE9A 4H30A 3KEKA 1BM6A 1GE5A 1IAEA 3P24A 1R1IA 1G05A 1OM8A 2V4BA 1ATLA 1HV5A 1I76A 3V96B 3KRYA 3DL1A 2JSDA 1WNIA 2X3AA 1OS2A 3MA2A 2WO9A 1UMSA 4XM8A 1G12A 2J83A 1MMRA 2O3EA 1A86A 1MMQA 1SLNA 3SHIA 2MZEA 5BPAA 1R1HA 1OM6A 1IADA 1DMTA 4GQLA 3F16A 3KMCA 3LILA 2X3CA 4G0DA 3LIRA 1UMTA 2DW0A 2Y6CA 1DTHA 1MMPA 1JAOA 2AYKA 2K2GA 3G42A 3TSKA 1K7QA 3F18A 4DV8A 1QUAA 2OXUA 1AF0A 3DNGA 1R1JA 3EDIA
chains in the Genus database with same CATH superfamily
3RTSA 4H76A 3DTKA 1GKDA 1BKCI 2MZHA 3ZXHA 3TVCA 3LJGA 1KUGA 3DWBA 1PWUA 3I7GA 3UVCA 2E2DA 1JJ9A 2MLSA 1BUDA 4PKTA 3B92A 1QJJA 2O36A 1IABA 3I7IA 4PKQA 1I73A 5I0LA 4L6TA 2OW0A 1BKCA 1JIWP 4GR8A 3G5CA 1KUHA 1H71P 1S4BP 1XFWA 1XUDA 3EDGA 4CTHA 4EFSA 3EHYA 2POJA 1EAKA 1G49A 3KMEA 2QPJA 5D2BA 2JIHA 5B5OA 1CAQA 1D8FA 1XFVA 3HDBA 1FLSA 1RM8A 1XFUA 4PKUA 4J4MA 3KHIA 1SU3A 3KECA 4A3WA 1CQRA 1ND1A 3K7LA 3EDZA 4H49A 1PWWA 4JP4A 3F19A 3VTGA 3HY9A 3BA0A 2YIGA 2E3XA 2DDYA 4FU4A 1R55A 4L19A 4AIGA 3EDHA 1G4KA 2L0RA 4GUYA 5D3CA 3OHLA 3AYUA 1Q3AA 2D1NA 1UTZA 1GE7A 2W15A 2TCLA 2Y6DA 1FM1A 3LEAA 4JIJA 1ZTQA 2MZIA 3LIKA 1SATA 1ZS0A 4QKZA 1PWPA 4IUWA 2N8RA 2OXZA 3HBVP 2OVXA 2USNA 2DW2A 1ZXVA 3KEJA 1OM7A 1XFXA 1HTDA 4H82A 3EWJA 4JA1A 3TS4A 5I2ZA 5D1TA 4L63A 4AYKA 4WF6A 3DSLA 1XFZA 5CUHA 4ZR5A 1ZVXA 2Z2DA 1CGLA 1GO8P 3O2XA 4XM7A 4XM6A 2OY2A 2ERPA 2DW1A 1YP1A 1GKCA 4FXYP 3P1VA 1IACA 2WOAA 3WV3A 2YB9A 1OZ9A 1CGFA 1ROSA 4FVLA 1ZXCA 1GXDA 2OW9A 3LJTA 3U1RA 2OXWA 2YUFA 1O0QA 2OW1A 1Y8JA 4G9LA 1Z3JA 4H3XA 1PWQA 4GWMA 1KUKA 1R54A 456CA 1HFSA 1SMPA 3ELMA 3LQBA 3NX7A 3L0TA 4H2EA 2OW2A 2OZRA 4L7AA 3WV1A 5JMYA 1HY7A 1K7GA 4HMAA 5I4OA 1USNA 1QICA 3HDAP 4PKVA 2KRJA 2WO8A 4AXQA 5I3MA 1O0TA 3DPFA 1KAPP 5L79A 2CLTA 3TT4A 3LUMA 1QJIA 1OO9A 3F1AA 3B2ZA 1KBCA 3B8ZA 1TVIA 3CKIA 1KUFA 1Y0VA 4JQGA 1B3DA 1JH1A 1BSWA 2W14A 4H1QA 1EB6A 1JAPA 1XUCA 3RTTA 3LUNA 4DF9A 1EUBA 1C8TA 1FBLA 4WK7A 966CA 1D5JA 2X3BA 3HB2P 2RJQA 2FV9A 1MNCA 4Q1LA 5LABA 4IN9A 1GE6A 1A85A 1JK3A 2JNPA 2OY4A 3DPEA 1RMZA 3LMCA 3Q2GA 3WV2A 1MMBA 3ZUKA 3GBOA 1CK7A 1PWVA 3N2UA 2W0DA 3LK8A 4JPAA 1SLMA 1C3IA 4GR3A 1D8MA 5I43A 1YQYA 5CZMA 1G9KA 5B5PA 1KUIA 1QIBA 4I03A 4XCTA 1L6JA 1JKYA 4GWNA 1ZP5A 1CXVA 1OS9A 3KWVC 3USNA 4XBHA 2EROA 1BUVM 2JT5A 3E8RA 5H8XA 4DD8A 3DTEA 1GO7P 4A7BA 3LKAA 4GF1A 3ZVSA 1SRPA 2OVZA 2W13A 5D1UA 1XURA 1YOUA 1XFYA 3DTIA 3O64A 4PKSA 1BZSA 3F17A 2CKIA 3OHOA 1QIAA 5BOYA 1CIZA 3VI1A 4DPEA 4WKEA 2X7MA 2A8HA 1Y93A 4AUOA 1J7NA 5BOTA 1XM5A 3AYKA 1JAQA 1BQOA 2ERQA 5D1SA 2OI0A 3HY7A 1BQQM 3F15A 5CXAA 4HX3A 1HOVA 2W12A 1HFCA 4ON1A 1I1IP 2XS3A 1IAGA 3L0VA 1JIZA 830CA 4GR0A 2XS4A 4H84A 2DDFA 3AIGA 4WKIA 4PKWA 2MLRA 3HYGA 1YCMA 1IAAA 2AIGP 4I35A 4WZVA 2HU6A 1CGEA 3Q2HA 2RJPA 2JT6A 3EHXA 1BIWA 1ASTA 5D7WA 2SRTA 1B8YA 1UEAA 4IJOA 1AYKA 2D1OA 4FXQA 2K9CA 1K7IA 3K7NA 1D7XA 2I47A 2J0TA 3LQ0A 4R3VA 5I12A 1AKLA 3HBUP 3N2VA 4PKRA 3LGPA 3LJZA 5L7FA 4ILWD 2PJTA 2FV5A 1JANA 1OMJA 1BKCE 1C7KA 1UTTA 3LE9A 4H30A 3KEKA 1BM6A 1GE5A 1IAEA 1XAXA 3P24A 1R1IA 1G05A 1OM8A 2V4BA 1ATLA 1HV5A 1I76A 3V96B 3KRYA 3DL1A 2JSDA 1WNIA 2X3AA 1OS2A 3MA2A 2WO9A 1UMSA 4XM8A 1G12A 2J83A 1MMRA 2O3EA 1A86A 1MMQA 1SLNA 3SHIA 2MZEA 5BPAA 1R1HA 1OM6A 1IADA 1DMTA 4GQLA 3F16A 3KMCA 3LILA 2X3CA 4G0DA 3LIRA 1UMTA 2DW0A 2Y6CA 1DTHA 1MMPA 1JAOA 2AYKA 2K2GA 3G42A 3TSKA 1K7QA 3F18A 4DV8A 1QUAA 2OXUA 1AF0A 3DNGA 1R1JA 3EDIA
chains in the Genus database with same CATH topology
3RTSA 4H76A 3DTKA 1GKDA 1BKCI 2MZHA 3ZXHA 3TVCA 3LJGA 1KUGA 3DWBA 1PWUA 3I7GA 3UVCA 2E2DA 1JJ9A 2MLSA 1BUDA 4PKTA 3B92A 1QJJA 2O36A 1IABA 3I7IA 4PKQA 1I73A 5I0LA 4L6TA 2OW0A 1BKCA 1JIWP 4GR8A 3G5CA 1KUHA 1H71P 1S4BP 1XFWA 1XUDA 3EDGA 4CTHA 4EFSA 3EHYA 2POJA 1EAKA 1G49A 3KMEA 2QPJA 5D2BA 2JIHA 5B5OA 1CAQA 1D8FA 1XFVA 3HDBA 1FLSA 1RM8A 1XFUA 4PKUA 4J4MA 3KHIA 1SU3A 3KECA 4A3WA 1CQRA 1ND1A 3K7LA 3EDZA 4H49A 1PWWA 4JP4A 3F19A 3VTGA 3HY9A 3BA0A 2YIGA 2E3XA 2DDYA 4FU4A 1R55A 4L19A 4AIGA 3EDHA 1G4KA 2L0RA 4GUYA 5D3CA 3OHLA 3AYUA 1Q3AA 2D1NA 1UTZA 1GE7A 2W15A 2TCLA 2Y6DA 1FM1A 3LEAA 4JIJA 1ZTQA 2MZIA 3LIKA 1SATA 1ZS0A 4QKZA 1PWPA 4IUWA 2N8RA 2OXZA 3HBVP 2OVXA 2USNA 2DW2A 1ZXVA 3KEJA 1OM7A 1XFXA 1HTDA 4H82A 3EWJA 4JA1A 3TS4A 5I2ZA 5D1TA 4L63A 4AYKA 4WF6A 3DSLA 1XFZA 5CUHA 4ZR5A 1ZVXA 2Z2DA 1CGLA 1GO8P 3O2XA 4XM7A 4XM6A 2OY2A 2ERPA 2DW1A 1YP1A 1GKCA 4FXYP 3P1VA 1IACA 2WOAA 3WV3A 2YB9A 1CGFA 1ROSA 4FVLA 1ZXCA 1GXDA 2OW9A 3LJTA 3U1RA 2OXWA 2YUFA 1O0QA 2OW1A 1Y8JA 4G9LA 1Z3JA 4H3XA 1PWQA 4GWMA 1KUKA 1R54A 456CA 1HFSA 1SMPA 3ELMA 3LQBA 3NX7A 3L0TA 4H2EA 2OW2A 2OZRA 4L7AA 3WV1A 5JMYA 1HY7A 1K7GA 4HMAA 5I4OA 1USNA 1QICA 3HDAP 4PKVA 2KRJA 2WO8A 4AXQA 5I3MA 1O0TA 3DPFA 1KAPP 5L79A 2CLTA 3TT4A 3LUMA 1QJIA 1OO9A 3F1AA 3B2ZA 1KBCA 3B8ZA 3CKIA 1KUFA 1Y0VA 4JQGA 1B3DA 1JH1A 1BSWA 2W14A 4H1QA 1EB6A 1JAPA 1XUCA 3RTTA 3LUNA 4DF9A 1EUBA 1C8TA 1FBLA 4WK7A 966CA 1D5JA 2X3BA 3HB2P 2RJQA 2FV9A 1MNCA 4Q1LA 5LABA 4IN9A 1GE6A 1A85A 1JK3A 2JNPA 2OY4A 3DPEA 1RMZA 3LMCA 3Q2GA 3WV2A 1MMBA 3ZUKA 3GBOA 1CK7A 1PWVA 3N2UA 2W0DA 3LK8A 4JPAA 1SLMA 1C3IA 4GR3A 1D8MA 5I43A 1YQYA 5CZMA 1G9KA 5B5PA 1KUIA 1QIBA 4I03A 4XCTA 1L6JA 1JKYA 4GWNA 1ZP5A 1CXVA 1OS9A 3KWVC 3USNA 4XBHA 2EROA 1BUVM 2JT5A 3E8RA 5H8XA 4DD8A 3DTEA 1GO7P 4A7BA 3LKAA 4GF1A 3ZVSA 1SRPA 2OVZA 2W13A 5D1UA 1XURA 1YOUA 1XFYA 3DTIA 3O64A 4PKSA 1BZSA 3F17A 2CKIA 3OHOA 1QIAA 5BOYA 1CIZA 3VI1A 4DPEA 4WKEA 2X7MA 2A8HA 1Y93A 4AUOA 1J7NA 5BOTA 3AYKA 1JAQA 1BQOA 2ERQA 5D1SA 2OI0A 3HY7A 1BQQM 3F15A 5CXAA 4HX3A 1HOVA 2W12A 1HFCA 4ON1A 1I1IP 2XS3A 1IAGA 3L0VA 1JIZA 830CA 4GR0A 2XS4A 4H84A 2DDFA 3AIGA 4WKIA 4PKWA 2MLRA 3HYGA 1YCMA 1IAAA 2AIGP 4I35A 4WZVA 2HU6A 1CGEA 3Q2HA 2RJPA 2JT6A 3EHXA 1BIWA 1ASTA 5D7WA 2SRTA 1B8YA 1UEAA 4IJOA 1AYKA 2D1OA 4FXQA 2K9CA 1K7IA 3K7NA 1D7XA 2I47A 2J0TA 3LQ0A 4R3VA 5I12A 1AKLA 3HBUP 3N2VA 4PKRA 3LGPA 3LJZA 5L7FA 4ILWD 2PJTA 2FV5A 1JANA 1OMJA 1BKCE 1C7KA 1UTTA 3LE9A 4H30A 3KEKA 1BM6A 1GE5A 1IAEA 3P24A 1R1IA 1G05A 1OM8A 2V4BA 1ATLA 1HV5A 1I76A 3V96B 3KRYA 3DL1A 2JSDA 1WNIA 2X3AA 1OS2A 3MA2A 2WO9A 1UMSA 4XM8A 1G12A 2J83A 1MMRA 2O3EA 1A86A 1MMQA 1SLNA 3SHIA 2MZEA 5BPAA 1R1HA 1OM6A 1IADA 1DMTA 4GQLA 3F16A 3KMCA 3LILA 2X3CA 4G0DA 3LIRA 1UMTA 2DW0A 2Y6CA 1DTHA 1MMPA 1JAOA 2AYKA 2K2GA 3G42A 3TSKA 1K7QA 3F18A 4DV8A 1QUAA 2OXUA 1AF0A 3DNGA 1R1JA 3EDIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3RTS A;  4H76 A;  1GKD A;  1BKC I;  2MZH A;  3ZXH A;  3TVC A;  3LJG A;  1KUG A;  3DWB A;  1PWU A;  3I7G A;  3UVC A;  2E2D A;  1JJ9 A;  2MLS A;  1BUD A;  4PKT A;  3B92 A;  1QJJ A;  2O36 A;  1IAB A;  3I7I A;  4PKQ A;  1I73 A;  5I0L A;  4L6T A;  2OW0 A;  1BKC A;  1JIW P;  4GR8 A;  3G5C A;  1KUH A;  1H71 P;  1S4B P;  1XFW A;  1XUD A;  3EDG A;  4CTH A;  4EFS A;  3EHY A;  2POJ A;  1EAK A;  1G49 A;  3KME A;  2QPJ A;  5D2B A;  2JIH A;  5B5O A;  1CAQ A;  1D8F A;  1XFV A;  3HDB A;  1FLS A;  1RM8 A;  1XFU A;  4PKU A;  4J4M A;  3KHI A;  1SU3 A;  3KEC A;  4A3W A;  1CQR A;  1ND1 A;  3K7L A;  3EDZ A;  4H49 A;  1PWW A;  4JP4 A;  3F19 A;  3VTG A;  3HY9 A;  3BA0 A;  2YIG A;  2E3X A;  2DDY A;  4FU4 A;  1R55 A;  4L19 A;  4AIG A;  3EDH A;  1G4K A;  2L0R A;  4GUY A;  5D3C A;  3OHL A;  3AYU A;  1Q3A A;  2D1N A;  1UTZ A;  1GE7 A;  2W15 A;  2TCL A;  2Y6D A;  1FM1 A;  3LEA A;  4JIJ A;  1ZTQ A;  2MZI A;  3LIK A;  1SAT A;  1ZS0 A;  4QKZ A;  1PWP A;  4IUW A;  2N8R A;  2OXZ A;  3HBV P;  2OVX A;  2USN A;  2DW2 A;  1ZXV A;  3KEJ A;  1OM7 A;  1XFX A;  1HTD A;  4H82 A;  3EWJ A;  4JA1 A;  3TS4 A;  5I2Z A;  5D1T A;  4L63 A;  4AYK A;  4WF6 A;  3DSL A;  1XFZ A;  5CUH A;  4ZR5 A;  1ZVX A;  2Z2D A;  1CGL A;  1GO8 P;  3O2X A;  4XM7 A;  4XM6 A;  2OY2 A;  2ERP A;  2DW1 A;  1YP1 A;  1GKC A;  4FXY P;  3P1V A;  1IAC A;  2WOA A;  3WV3 A;  2YB9 A;  1CGF A;  1ROS A;  4FVL A;  1ZXC A;  1GXD A;  2OW9 A;  3LJT A;  3U1R A;  2OXW A;  1O0Q A;  2OW1 A;  1Y8J A;  4G9L A;  1Z3J A;  4H3X A;  1PWQ A;  4GWM A;  1KUK A;  1R54 A;  456C A;  1HFS A;  1SMP A;  3ELM A;  3LQB A;  3NX7 A;  3L0T A;  4H2E A;  2OW2 A;  2OZR A;  3WV1 A;  5JMY A;  1HY7 A;  1K7G A;  4HMA A;  5I4O A;  1USN A;  1QIC A;  3HDA P;  4PKV A;  2KRJ A;  2WO8 A;  4AXQ A;  5I3M A;  1O0T A;  3DPF A;  1KAP P;  5L79 A;  2CLT A;  3TT4 A;  3LUM A;  1QJI A;  1OO9 A;  3F1A A;  3B2Z A;  1KBC A;  3B8Z A;  3CKI A;  1KUF A;  1Y0V A;  4JQG A;  1B3D A;  1JH1 A;  1BSW A;  2W14 A;  4H1Q A;  1EB6 A;  1JAP A;  1XUC A;  3RTT A;  3LUN A;  4DF9 A;  1EUB A;  1C8T A;  1FBL A;  4WK7 A;  966C A;  1D5J A;  2X3B A;  3HB2 P;  2RJQ A;  2FV9 A;  1MNC A;  4Q1L A;  5LAB A;  4IN9 A;  1GE6 A;  1A85 A;  1JK3 A;  2JNP A;  2OY4 A;  3DPE A;  1RMZ A;  3LMC A;  3Q2G A;  3WV2 A;  1MMB A;  3ZUK A;  3GBO A;  1CK7 A;  1PWV A;  3N2U A;  2W0D A;  3LK8 A;  4JPA A;  1SLM A;  1C3I A;  4GR3 A;  1D8M A;  5I43 A;  1YQY A;  5CZM A;  1G9K A;  5B5P A;  1KUI A;  1QIB A;  4I03 A;  4XCT A;  1L6J A;  1JKY A;  4GWN A;  1ZP5 A;  1CXV A;  1OS9 A;  3KWV C;  3USN A;  4XBH A;  2ERO A;  1BUV M;  2JT5 A;  3E8R A;  5H8X A;  4DD8 A;  1GO7 P;  4A7B A;  3LKA A;  4GF1 A;  3ZVS A;  1SRP A;  2OVZ A;  2W13 A;  5D1U A;  1XUR A;  1YOU A;  1XFY A;  3O64 A;  4PKS A;  1BZS A;  3F17 A;  2CKI A;  3OHO A;  1QIA A;  5BOY A;  1CIZ A;  3VI1 A;  4DPE A;  4WKE A;  2X7M A;  2A8H A;  1Y93 A;  4AUO A;  1J7N A;  5BOT A;  3AYK A;  1JAQ A;  1BQO A;  2ERQ A;  5D1S A;  2OI0 A;  3HY7 A;  1BQQ M;  3F15 A;  5CXA A;  4HX3 A;  1HOV A;  2W12 A;  1HFC A;  4ON1 A;  1I1I P;  2XS3 A;  1IAG A;  3L0V A;  1JIZ A;  830C A;  4GR0 A;  2XS4 A;  4H84 A;  2DDF A;  3AIG A;  4WKI A;  4PKW A;  2MLR A;  3HYG A;  1YCM A;  1IAA A;  2AIG P;  4I35 A;  4WZV A;  2HU6 A;  1CGE A;  3Q2H A;  2RJP A;  2JT6 A;  3EHX A;  1BIW A;  1AST A;  5D7W A;  2SRT A;  1B8Y A;  1UEA A;  4IJO A;  1AYK A;  2D1O A;  4FXQ A;  2K9C A;  1K7I A;  3K7N A;  1D7X A;  2I47 A;  2J0T A;  3LQ0 A;  4R3V A;  5I12 A;  1AKL A;  3HBU P;  3N2V A;  4PKR A;  3LGP A;  3LJZ A;  5L7F A;  4ILW D;  2PJT A;  2FV5 A;  1JAN A;  1OMJ A;  1BKC E;  1C7K A;  1UTT A;  3LE9 A;  4H30 A;  3KEK A;  1BM6 A;  1GE5 A;  1IAE A;  3P24 A;  1R1I A;  1G05 A;  1OM8 A;  2V4B A;  1ATL A;  1HV5 A;  1I76 A;  3V96 B;  3KRY A;  3DL1 A;  2JSD A;  1WNI A;  2X3A A;  1OS2 A;  3MA2 A;  2WO9 A;  1UMS A;  4XM8 A;  1G12 A;  2J83 A;  1MMR A;  2O3E A;  1A86 A;  1MMQ A;  1SLN A;  3SHI A;  2MZE A;  5BPA A;  1R1H A;  1OM6 A;  1IAD A;  1DMT A;  4GQL A;  3F16 A;  3KMC A;  3LIL A;  2X3C A;  4G0D A;  3LIR A;  1UMT A;  2DW0 A;  2Y6C A;  1DTH A;  1MMP A;  1JAO A;  2AYK A;  2K2G A;  3G42 A;  3TSK A;  1K7Q A;  3F18 A;  4DV8 A;  1QUA A;  2OXU A;  1AF0 A;  3DNG A;  1R1J A;  3EDI A; 
#chains in the Genus database with same CATH topology
 3RTS A;  4H76 A;  3DTK A;  1GKD A;  1BKC I;  2MZH A;  3ZXH A;  3TVC A;  3LJG A;  1KUG A;  3DWB A;  1PWU A;  3I7G A;  3UVC A;  2E2D A;  1JJ9 A;  2MLS A;  1BUD A;  4PKT A;  3B92 A;  1QJJ A;  2O36 A;  1IAB A;  3I7I A;  4PKQ A;  1I73 A;  5I0L A;  4L6T A;  2OW0 A;  1BKC A;  1JIW P;  4GR8 A;  3G5C A;  1KUH A;  1H71 P;  1S4B P;  1XFW A;  1XUD A;  3EDG A;  4CTH A;  4EFS A;  3EHY A;  2POJ A;  1EAK A;  1G49 A;  3KME A;  2QPJ A;  5D2B A;  2JIH A;  5B5O A;  1CAQ A;  1D8F A;  1XFV A;  3HDB A;  1FLS A;  1RM8 A;  1XFU A;  4PKU A;  4J4M A;  3KHI A;  1SU3 A;  3KEC A;  4A3W A;  1CQR A;  1ND1 A;  3K7L A;  3EDZ A;  4H49 A;  1PWW A;  4JP4 A;  3F19 A;  3VTG A;  3HY9 A;  3BA0 A;  2YIG A;  2E3X A;  2DDY A;  4FU4 A;  1R55 A;  4L19 A;  4AIG A;  3EDH A;  1G4K A;  2L0R A;  4GUY A;  5D3C A;  3OHL A;  3AYU A;  1Q3A A;  2D1N A;  1UTZ A;  1GE7 A;  2W15 A;  2TCL A;  2Y6D A;  1FM1 A;  3LEA A;  4JIJ A;  1ZTQ A;  2MZI A;  3LIK A;  1SAT A;  1ZS0 A;  4QKZ A;  1PWP A;  4IUW A;  2N8R A;  2OXZ A;  3HBV P;  2OVX A;  2USN A;  2DW2 A;  1ZXV A;  3KEJ A;  1OM7 A;  1XFX A;  1HTD A;  4H82 A;  3EWJ A;  4JA1 A;  3TS4 A;  5I2Z A;  5D1T A;  4L63 A;  4AYK A;  4WF6 A;  3DSL A;  1XFZ A;  5CUH A;  4ZR5 A;  1ZVX A;  2Z2D A;  1CGL A;  1GO8 P;  3O2X A;  4XM7 A;  4XM6 A;  2OY2 A;  2ERP A;  2DW1 A;  1YP1 A;  1GKC A;  4FXY P;  3P1V A;  1IAC A;  2WOA A;  3WV3 A;  2YB9 A;  1OZ9 A;  1CGF A;  1ROS A;  4FVL A;  1ZXC A;  1GXD A;  2OW9 A;  3LJT A;  3U1R A;  2OXW A;  2YUF A;  1O0Q A;  2OW1 A;  1Y8J A;  4G9L A;  1Z3J A;  4H3X A;  1PWQ A;  4GWM A;  1KUK A;  1R54 A;  456C A;  1HFS A;  1SMP A;  3ELM A;  3LQB A;  3NX7 A;  3L0T A;  4H2E A;  2OW2 A;  2OZR A;  4L7A A;  3WV1 A;  5JMY A;  1HY7 A;  1K7G A;  4HMA A;  5I4O A;  1USN A;  1QIC A;  3HDA P;  4PKV A;  2KRJ A;  2WO8 A;  4AXQ A;  5I3M A;  1O0T A;  3DPF A;  1KAP P;  5L79 A;  2CLT A;  3TT4 A;  3LUM A;  1QJI A;  1OO9 A;  3F1A A;  3B2Z A;  1KBC A;  3B8Z A;  1TVI A;  3CKI A;  1KUF A;  1Y0V A;  4JQG A;  1B3D A;  1JH1 A;  1BSW A;  2W14 A;  4H1Q A;  1EB6 A;  1JAP A;  1XUC A;  3RTT A;  3LUN A;  4DF9 A;  1EUB A;  1C8T A;  1FBL A;  4WK7 A;  966C A;  1D5J A;  2X3B A;  3HB2 P;  2RJQ A;  2FV9 A;  1MNC A;  4Q1L A;  5LAB A;  4IN9 A;  1GE6 A;  1A85 A;  1JK3 A;  2JNP A;  2OY4 A;  3DPE A;  1RMZ A;  3LMC A;  3Q2G A;  3WV2 A;  1MMB A;  3ZUK A;  3GBO A;  1CK7 A;  1PWV A;  3N2U A;  2W0D A;  3LK8 A;  4JPA A;  1SLM A;  1C3I A;  4GR3 A;  1D8M A;  5I43 A;  1YQY A;  5CZM A;  1G9K A;  5B5P A;  1KUI A;  1QIB A;  4I03 A;  4XCT A;  1L6J A;  1JKY A;  4GWN A;  1ZP5 A;  1CXV A;  1OS9 A;  3KWV C;  3USN A;  4XBH A;  2ERO A;  1BUV M;  2JT5 A;  3E8R A;  5H8X A;  4DD8 A;  3DTE A;  1GO7 P;  4A7B A;  3LKA A;  4GF1 A;  3ZVS A;  1SRP A;  2OVZ A;  2W13 A;  5D1U A;  1XUR A;  1YOU A;  1XFY A;  3DTI A;  3O64 A;  4PKS A;  1BZS A;  3F17 A;  2CKI A;  3OHO A;  1QIA A;  5BOY A;  1CIZ A;  3VI1 A;  4DPE A;  4WKE A;  2X7M A;  2A8H A;  1Y93 A;  4AUO A;  1J7N A;  5BOT A;  1XM5 A;  3AYK A;  1JAQ A;  1BQO A;  2ERQ A;  5D1S A;  2OI0 A;  3HY7 A;  1BQQ M;  3F15 A;  5CXA A;  4HX3 A;  1HOV A;  2W12 A;  1HFC A;  4ON1 A;  1I1I P;  2XS3 A;  1IAG A;  3L0V A;  1JIZ A;  830C A;  4GR0 A;  2XS4 A;  4H84 A;  2DDF A;  3AIG A;  4WKI A;  4PKW A;  2MLR A;  3HYG A;  1YCM A;  1IAA A;  2AIG P;  4I35 A;  4WZV A;  2HU6 A;  1CGE A;  3Q2H A;  2RJP A;  2JT6 A;  3EHX A;  1BIW A;  1AST A;  5D7W A;  2SRT A;  1B8Y A;  1UEA A;  4IJO A;  1AYK A;  2D1O A;  4FXQ A;  2K9C A;  1K7I A;  3K7N A;  1D7X A;  2I47 A;  2J0T A;  3LQ0 A;  4R3V A;  5I12 A;  1AKL A;  3HBU P;  3N2V A;  4PKR A;  3LGP A;  3LJZ A;  5L7F A;  4ILW D;  2PJT A;  2FV5 A;  1JAN A;  1OMJ A;  1BKC E;  1C7K A;  1UTT A;  3LE9 A;  4H30 A;  3KEK A;  1BM6 A;  1GE5 A;  1IAE A;  1XAX A;  3P24 A;  1R1I A;  1G05 A;  1OM8 A;  2V4B A;  1ATL A;  1HV5 A;  1I76 A;  3V96 B;  3KRY A;  3DL1 A;  2JSD A;  1WNI A;  2X3A A;  1OS2 A;  3MA2 A;  2WO9 A;  1UMS A;  4XM8 A;  1G12 A;  2J83 A;  1MMR A;  2O3E A;  1A86 A;  1MMQ A;  1SLN A;  3SHI A;  2MZE A;  5BPA A;  1R1H A;  1OM6 A;  1IAD A;  1DMT A;  4GQL A;  3F16 A;  3KMC A;  3LIL A;  2X3C A;  4G0D A;  3LIR A;  1UMT A;  2DW0 A;  2Y6C A;  1DTH A;  1MMP A;  1JAO A;  2AYK A;  2K2G A;  3G42 A;  3TSK A;  1K7Q A;  3F18 A;  4DV8 A;  1QUA A;  2OXU A;  1AF0 A;  3DNG A;  1R1J A;  3EDI A; 
#chains in the Genus database with same CATH homology
 3RTS A;  4H76 A;  3DTK A;  1GKD A;  1BKC I;  2MZH A;  3ZXH A;  3TVC A;  3LJG A;  1KUG A;  3DWB A;  1PWU A;  3I7G A;  3UVC A;  2E2D A;  1JJ9 A;  2MLS A;  1BUD A;  4PKT A;  3B92 A;  1QJJ A;  2O36 A;  1IAB A;  3I7I A;  4PKQ A;  1I73 A;  5I0L A;  4L6T A;  2OW0 A;  1BKC A;  1JIW P;  4GR8 A;  3G5C A;  1KUH A;  1H71 P;  1S4B P;  1XFW A;  1XUD A;  3EDG A;  4CTH A;  4EFS A;  3EHY A;  2POJ A;  1EAK A;  1G49 A;  3KME A;  2QPJ A;  5D2B A;  2JIH A;  5B5O A;  1CAQ A;  1D8F A;  1XFV A;  3HDB A;  1FLS A;  1RM8 A;  1XFU A;  4PKU A;  4J4M A;  3KHI A;  1SU3 A;  3KEC A;  4A3W A;  1CQR A;  1ND1 A;  3K7L A;  3EDZ A;  4H49 A;  1PWW A;  4JP4 A;  3F19 A;  3VTG A;  3HY9 A;  3BA0 A;  2YIG A;  2E3X A;  2DDY A;  4FU4 A;  1R55 A;  4L19 A;  4AIG A;  3EDH A;  1G4K A;  2L0R A;  4GUY A;  5D3C A;  3OHL A;  3AYU A;  1Q3A A;  2D1N A;  1UTZ A;  1GE7 A;  2W15 A;  2TCL A;  2Y6D A;  1FM1 A;  3LEA A;  4JIJ A;  1ZTQ A;  2MZI A;  3LIK A;  1SAT A;  1ZS0 A;  4QKZ A;  1PWP A;  4IUW A;  2N8R A;  2OXZ A;  3HBV P;  2OVX A;  2USN A;  2DW2 A;  1ZXV A;  3KEJ A;  1OM7 A;  1XFX A;  1HTD A;  4H82 A;  3EWJ A;  4JA1 A;  3TS4 A;  5I2Z A;  5D1T A;  4L63 A;  4AYK A;  4WF6 A;  3DSL A;  1XFZ A;  5CUH A;  4ZR5 A;  1ZVX A;  2Z2D A;  1CGL A;  1GO8 P;  3O2X A;  4XM7 A;  4XM6 A;  2OY2 A;  2ERP A;  2DW1 A;  1YP1 A;  1GKC A;  4FXY P;  3P1V A;  1IAC A;  2WOA A;  3WV3 A;  2YB9 A;  1CGF A;  1ROS A;  4FVL A;  1ZXC A;  1GXD A;  2OW9 A;  3LJT A;  3U1R A;  2OXW A;  2YUF A;  1O0Q A;  2OW1 A;  1Y8J A;  4G9L A;  1Z3J A;  4H3X A;  1PWQ A;  4GWM A;  1KUK A;  1R54 A;  456C A;  1HFS A;  1SMP A;  3ELM A;  3LQB A;  3NX7 A;  3L0T A;  4H2E A;  2OW2 A;  2OZR A;  4L7A A;  3WV1 A;  5JMY A;  1HY7 A;  1K7G A;  4HMA A;  5I4O A;  1USN A;  1QIC A;  3HDA P;  4PKV A;  2KRJ A;  2WO8 A;  4AXQ A;  5I3M A;  1O0T A;  3DPF A;  1KAP P;  5L79 A;  2CLT A;  3TT4 A;  3LUM A;  1QJI A;  1OO9 A;  3F1A A;  3B2Z A;  1KBC A;  3B8Z A;  3CKI A;  1KUF A;  1Y0V A;  4JQG A;  1B3D A;  1JH1 A;  1BSW A;  2W14 A;  4H1Q A;  1EB6 A;  1JAP A;  1XUC A;  3RTT A;  3LUN A;  4DF9 A;  1EUB A;  1C8T A;  1FBL A;  4WK7 A;  966C A;  1D5J A;  2X3B A;  3HB2 P;  2RJQ A;  2FV9 A;  1MNC A;  4Q1L A;  5LAB A;  4IN9 A;  1GE6 A;  1A85 A;  1JK3 A;  2JNP A;  2OY4 A;  3DPE A;  1RMZ A;  3LMC A;  3Q2G A;  3WV2 A;  1MMB A;  3ZUK A;  3GBO A;  1CK7 A;  1PWV A;  3N2U A;  2W0D A;  3LK8 A;  4JPA A;  1SLM A;  1C3I A;  4GR3 A;  1D8M A;  5I43 A;  1YQY A;  5CZM A;  1G9K A;  5B5P A;  1KUI A;  1QIB A;  4I03 A;  4XCT A;  1L6J A;  1JKY A;  4GWN A;  1ZP5 A;  1CXV A;  1OS9 A;  3KWV C;  3USN A;  4XBH A;  2ERO A;  1BUV M;  2JT5 A;  3E8R A;  5H8X A;  4DD8 A;  3DTE A;  1GO7 P;  4A7B A;  3LKA A;  4GF1 A;  3ZVS A;  1SRP A;  2OVZ A;  2W13 A;  5D1U A;  1XUR A;  1YOU A;  1XFY A;  3DTI A;  3O64 A;  4PKS A;  1BZS A;  3F17 A;  2CKI A;  3OHO A;  1QIA A;  5BOY A;  1CIZ A;  3VI1 A;  4DPE A;  4WKE A;  2X7M A;  2A8H A;  1Y93 A;  4AUO A;  1J7N A;  5BOT A;  3AYK A;  1JAQ A;  1BQO A;  2ERQ A;  5D1S A;  2OI0 A;  3HY7 A;  1BQQ M;  3F15 A;  5CXA A;  4HX3 A;  1HOV A;  2W12 A;  1HFC A;  4ON1 A;  1I1I P;  2XS3 A;  1IAG A;  3L0V A;  1JIZ A;  830C A;  4GR0 A;  2XS4 A;  4H84 A;  2DDF A;  3AIG A;  4WKI A;  4PKW A;  2MLR A;  3HYG A;  1YCM A;  1IAA A;  2AIG P;  4I35 A;  4WZV A;  2HU6 A;  1CGE A;  3Q2H A;  2RJP A;  2JT6 A;  3EHX A;  1BIW A;  1AST A;  5D7W A;  2SRT A;  1B8Y A;  1UEA A;  4IJO A;  1AYK A;  2D1O A;  4FXQ A;  2K9C A;  1K7I A;  3K7N A;  1D7X A;  2I47 A;  2J0T A;  3LQ0 A;  4R3V A;  5I12 A;  1AKL A;  3HBU P;  3N2V A;  4PKR A;  3LGP A;  3LJZ A;  5L7F A;  4ILW D;  2PJT A;  2FV5 A;  1JAN A;  1OMJ A;  1BKC E;  1C7K A;  1UTT A;  3LE9 A;  4H30 A;  3KEK A;  1BM6 A;  1GE5 A;  1IAE A;  3P24 A;  1R1I A;  1G05 A;  1OM8 A;  2V4B A;  1ATL A;  1HV5 A;  1I76 A;  3V96 B;  3KRY A;  3DL1 A;  2JSD A;  1WNI A;  2X3A A;  1OS2 A;  3MA2 A;  2WO9 A;  1UMS A;  4XM8 A;  1G12 A;  2J83 A;  1MMR A;  2O3E A;  1A86 A;  1MMQ A;  1SLN A;  3SHI A;  2MZE A;  5BPA A;  1R1H A;  1OM6 A;  1IAD A;  1DMT A;  4GQL A;  3F16 A;  3KMC A;  3LIL A;  2X3C A;  4G0D A;  3LIR A;  1UMT A;  2DW0 A;  2Y6C A;  1DTH A;  1MMP A;  1JAO A;  2AYK A;  2K2G A;  3G42 A;  3TSK A;  1K7Q A;  3F18 A;  4DV8 A;  1QUA A;  2OXU A;  1AF0 A;  3DNG A;  1R1J A;  3EDI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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