1BKDS

Complex of human h-ras with human sos-1
Total Genus 156
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
156
sequence length
477
structure length
439
Chain Sequence
RLPSADVYRFAEPDSEENIIFEEGIPIIKAGTVIKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLIIERFEIPEPRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDAYLLQRMEEFIGTVRGKAMKKWVESITKIIQRKKITFQSSPPTVEWHISRPGHIETFDLLTLHPIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKILEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELINFSKRRKVAEITGEIQQYQNQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRNPKPLPRFPKKYSYPLKSPGVRPSN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Complex(oncogene protein/exchange factor)
molecule keywords H-RAS
publication title The structural basis of the activation of Ras by Sos.
pubmed doi rcsb
source organism Homo sapiens
total genus 156
structure length 439
sequence length 477
ec nomenclature
pdb deposition date 1998-07-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
S PF00617 RasGEF RasGEF domain
S PF00618 RasGEF_N RasGEF N-terminal motif
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.840.10 Mainly Alpha Orthogonal Bundle Son of Sevenless (SoS) protein; Chain S, domain 2 Ras guanine-nucleotide exchange factors catalytic domain 1bkdS02
1.20.870.10 Mainly Alpha Up-down Bundle Son of sevenless (SoS) protein; Chain S, domain 1 Son of sevenless (SoS) protein Chain: S domain 1 1bkdS01
3KSYA 4MGKE 4MGIE 3QXLA 4URUS 1NVUS 4URVS 1NVXS 4MH0E 4US1S 5CM8A 3T6AA 5CM9A 4NYIS 4L9MA 1XD2C 4NYJS 4NYMS 2IJES 4URXS 3T6GA 4URYS 4MGYE 3CF6E 4US0S 4US2S 4MGZE 1XD4A 4JGWA 2BYVE 2II0A 4URWS 4URZS 1BKDS 1NVWS 4F7ZA 1NVVS
chains in the Genus database with same CATH superfamily
3KSYA 4MGKE 4MGIE 3QXLA 4URUS 1NVUS 4URVS 1NVXS 4MH0E 4US1S 5CM8A 3T6AA 5CM9A 4NYIS 4L9MA 1XD2C 4NYJS 4NYMS 2IJES 4URXS 3T6GA 4URYS 4MGYE 3CF6E 4US0S 4US2S 4MGZE 1XD4A 4JGWA 2BYVE 2II0A 4URWS 4URZS 1BKDS 1NVWS 4F7ZA 1NVVS
chains in the Genus database with same CATH topology
3KSYA 4MGKE 4MGIE 3QXLA 4URUS 1NVUS 4URVS 1NVXS 4MH0E 4US1S 5CM8A 3T6AA 5CM9A 4NYIS 4L9MA 1XD2C 4NYJS 4NYMS 2IJES 4URXS 3T6GA 4URYS 4MGYE 3CF6E 4US0S 4US2S 4MGZE 1XD4A 4JGWA 2BYVE 2II0A 4URWS 4URZS 1BKDS 1NVWS 4F7ZA 1NVVS
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3KSY A;  4MGK E;  4MGI E;  3QXL A;  4URU S;  1NVU S;  4URV S;  1NVX S;  4MH0 E;  4US1 S;  5CM8 A;  3T6A A;  5CM9 A;  4NYI S;  4L9M A;  1XD2 C;  4NYJ S;  4NYM S;  2IJE S;  4URX S;  3T6G A;  4URY S;  4MGY E;  3CF6 E;  4US0 S;  4US2 S;  4MGZ E;  1XD4 A;  4JGW A;  2BYV E;  2II0 A;  4URW S;  4URZ S;  1BKD S;  1NVW S;  4F7Z A;  1NVV S; 
#chains in the Genus database with same CATH topology
 3KSY A;  4MGK E;  4MGI E;  3QXL A;  4URU S;  1NVU S;  4URV S;  1NVX S;  4MH0 E;  4US1 S;  5CM8 A;  3T6A A;  5CM9 A;  4NYI S;  4L9M A;  1XD2 C;  4NYJ S;  4NYM S;  2IJE S;  4URX S;  3T6G A;  4URY S;  4MGY E;  3CF6 E;  4US0 S;  4US2 S;  4MGZ E;  1XD4 A;  4JGW A;  2BYV E;  2II0 A;  4URW S;  4URZ S;  1BKD S;  1NVW S;  4F7Z A;  1NVV S; 
#chains in the Genus database with same CATH homology
 3KSY A;  4MGK E;  4MGI E;  3QXL A;  4URU S;  1NVU S;  4URV S;  1NVX S;  4MH0 E;  4US1 S;  5CM8 A;  3T6A A;  5CM9 A;  4NYI S;  4L9M A;  1XD2 C;  4NYJ S;  4NYM S;  2IJE S;  4URX S;  3T6G A;  4URY S;  4MGY E;  3CF6 E;  4US0 S;  4US2 S;  4MGZ E;  1XD4 A;  4JGW A;  2BYV E;  2II0 A;  4URW S;  4URZ S;  1BKD S;  1NVW S;  4F7Z A;  1NVV S; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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