1BKDS

Complex of human h-ras with human sos-1
Total Genus 156
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
156
sequence length
477
structure length
439
Chain Sequence
RLPSADVYRFAEPDSEENIIFEEGIPIIKAGTVIKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLIIERFEIPEPRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDAYLLQRMEEFIGTVRGKAMKKWVESITKIIQRKKITFQSSPPTVEWHISRPGHIETFDLLTLHPIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKILEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELINFSKRRKVAEITGEIQQYQNQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRNPKPLPRFPKKYSYPLKSPGVRPSN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The structural basis of the activation of Ras by Sos.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Complex(oncogene protein/exchange factor)
molecule keywords H-RAS
total genus 156
structure length 439
sequence length 477
ec nomenclature
pdb deposition date 1998-07-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
S PF00617 RasGEF RasGEF domain
S PF00618 RasGEF_N RasGEF N-terminal motif
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.840.10 Mainly Alpha Orthogonal Bundle Son of Sevenless (SoS) protein; Chain S, domain 2 Ras guanine-nucleotide exchange factors catalytic domain 1bkdS02
1.20.870.10 Mainly Alpha Up-down Bundle Son of sevenless (SoS) protein; Chain S, domain 1 Son of sevenless (SoS) protein Chain: S domain 1 1bkdS01
1NVUS 1NVWS 4NYMS 4URYS 4URZS 4URUS 2BYVE 4US0S 4MGZE 4NYJS 4US2S 4F7ZA 4URXS 3T6GA 1XD4A 4NYIS 3KSYA 3T6AA 3CF6E 4JGWA 1BKDS 1NVVS 4URWS 4URVS 1NVXS 4MGIE 2IJES 4MH0E 2II0A 4MGKE 1XD2C 5CM8A 5CM9A 3QXLA 4US1S 4L9MA 4MGYE
chains in the Genus database with same CATH superfamily
1NVUS 1NVWS 4NYMS 4URYS 4URZS 4URUS 2BYVE 4US0S 4MGZE 4NYJS 4US2S 4F7ZA 4URXS 3T6GA 1XD4A 4NYIS 3KSYA 3T6AA 3CF6E 4JGWA 1BKDS 1NVVS 4URWS 4URVS 1NVXS 4MGIE 2IJES 4MH0E 2II0A 4MGKE 1XD2C 5CM8A 5CM9A 3QXLA 4US1S 4L9MA 4MGYE
chains in the Genus database with same CATH topology
1NVUS 1NVWS 4NYMS 4URYS 4URZS 4URUS 2BYVE 4US0S 4MGZE 4NYJS 4US2S 4F7ZA 4URXS 3T6GA 1XD4A 4NYIS 3KSYA 3T6AA 3CF6E 4JGWA 1BKDS 1NVVS 4URWS 4URVS 1NVXS 4MGIE 2IJES 4MH0E 2II0A 4MGKE 1XD2C 5CM8A 5CM9A 3QXLA 4US1S 4L9MA 4MGYE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1NVU S;  1NVW S;  4NYM S;  4URY S;  4URZ S;  4URU S;  2BYV E;  4US0 S;  4MGZ E;  4NYJ S;  4US2 S;  4F7Z A;  4URX S;  3T6G A;  1XD4 A;  4NYI S;  3KSY A;  3T6A A;  3CF6 E;  4JGW A;  1BKD S;  1NVV S;  4URW S;  4URV S;  1NVX S;  4MGI E;  2IJE S;  4MH0 E;  2II0 A;  4MGK E;  1XD2 C;  5CM8 A;  5CM9 A;  3QXL A;  4US1 S;  4L9M A;  4MGY E; 
#chains in the Genus database with same CATH topology
 1NVU S;  1NVW S;  4NYM S;  4URY S;  4URZ S;  4URU S;  2BYV E;  4US0 S;  4MGZ E;  4NYJ S;  4US2 S;  4F7Z A;  4URX S;  3T6G A;  1XD4 A;  4NYI S;  3KSY A;  3T6A A;  3CF6 E;  4JGW A;  1BKD S;  1NVV S;  4URW S;  4URV S;  1NVX S;  4MGI E;  2IJE S;  4MH0 E;  2II0 A;  4MGK E;  1XD2 C;  5CM8 A;  5CM9 A;  3QXL A;  4US1 S;  4L9M A;  4MGY E; 
#chains in the Genus database with same CATH homology
 1NVU S;  1NVW S;  4NYM S;  4URY S;  4URZ S;  4URU S;  2BYV E;  4US0 S;  4MGZ E;  4NYJ S;  4US2 S;  4F7Z A;  4URX S;  3T6G A;  1XD4 A;  4NYI S;  3KSY A;  3T6A A;  3CF6 E;  4JGW A;  1BKD S;  1NVV S;  4URW S;  4URV S;  1NVX S;  4MGI E;  2IJE S;  4MH0 E;  2II0 A;  4MGK E;  1XD2 C;  5CM8 A;  5CM9 A;  3QXL A;  4US1 S;  4L9M A;  4MGY E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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