1BOWA

Multidrug-binding domain of transcription activator bmrr (apo form)
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
158
structure length
143
Chain Sequence
RLGEVFVLDEEEIRIIQTEAEGIGPENVLNASYSKLKKFIESNNSYGATFSFQPYTSIDEMTYRHIFTPVLISSITPDMEITTIPKGRYACIAYNFSPEHYFLNLQKLIKYIADRQLTVVSDVYELIIPIHYEYRVEMKIRIL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of multidrug recognition by BmrR, a transcription activator of a multidrug transporter.
pubmed doi rcsb
molecule tags Transcription activator
source organism Bacillus subtilis
molecule keywords MULTIDRUG-EFFLUX TRANSPORTER 1 REGULATOR BMRR
total genus 26
structure length 143
sequence length 158
ec nomenclature
pdb deposition date 1998-08-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF06445 GyrI-like GyrI-like small molecule binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.20.80.10 Alpha Beta Alpha-Beta Barrel Multidrug-efflux Transporter 1 Regulator Bmrr; Chain A Regulatory factor, effector binding domain 1bowA00
2BOWA 3B49A 3GK6A 3D6ZA 5KAXA 5KCBA 3Q1MA 1EXJA 5GQQA 1BOWA 3E0HA 2KCUA 3D6YA 4A1MA 5KATA 1R8EA 1JYHA 3LURA 5KAWA 3Q5SA 2HVAA 3Q5PA 1EXIA 3R8KA 3Q3DA 3D70A 3Q5RA 4AYZA 2GOVA 4B0YA 4AYZB 3IAOA 3D71A 3R8JA 5KAVA 3Q2YA 5KAUA 1D5YA
chains in the Genus database with same CATH superfamily
2BOWA 3B49A 3GK6A 3D6ZA 5KAXA 5KCBA 3Q1MA 1EXJA 5GQQA 1BOWA 3E0HA 2KCUA 3D6YA 4A1MA 5KATA 1R8EA 1JYHA 3LURA 5KAWA 3Q5SA 2HVAA 3Q5PA 1EXIA 3R8KA 3Q3DA 3D70A 3Q5RA 4AYZA 2GOVA 4B0YA 4AYZB 3IAOA 3D71A 3R8JA 5KAVA 3Q2YA 5KAUA 1D5YA
chains in the Genus database with same CATH topology
2BOWA 3B49A 3GK6A 3D6ZA 5KAXA 5KCBA 3Q1MA 1EXJA 5GQQA 1BOWA 3E0HA 2KCUA 3D6YA 4A1MA 5KATA 1R8EA 1JYHA 3LURA 5KAWA 3Q5SA 2HVAA 3Q5PA 1EXIA 3R8KA 3Q3DA 3D70A 3Q5RA 4AYZA 2GOVA 4B0YA 4AYZB 3IAOA 3D71A 3R8JA 5KAVA 3Q2YA 5KAUA 1D5YA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2BOW A;  3B49 A;  3GK6 A;  3D6Z A;  5KAX A;  5KCB A;  3Q1M A;  1EXJ A;  5GQQ A;  1BOW A;  3E0H A;  2KCU A;  3D6Y A;  4A1M A;  5KAT A;  1R8E A;  1JYH A;  3LUR A;  5KAW A;  3Q5S A;  2HVA A;  3Q5P A;  1EXI A;  3R8K A;  3Q3D A;  3D70 A;  3Q5R A;  4AYZ A;  2GOV A;  4B0Y A;  4AYZ B;  3IAO A;  3D71 A;  3R8J A;  5KAV A;  3Q2Y A;  5KAU A;  1D5Y A; 
#chains in the Genus database with same CATH topology
 2BOW A;  3B49 A;  3GK6 A;  3D6Z A;  5KAX A;  5KCB A;  3Q1M A;  1EXJ A;  5GQQ A;  1BOW A;  3E0H A;  2KCU A;  3D6Y A;  4A1M A;  5KAT A;  1R8E A;  1JYH A;  3LUR A;  5KAW A;  3Q5S A;  2HVA A;  3Q5P A;  1EXI A;  3R8K A;  3Q3D A;  3D70 A;  3Q5R A;  4AYZ A;  2GOV A;  4B0Y A;  4AYZ B;  3IAO A;  3D71 A;  3R8J A;  5KAV A;  3Q2Y A;  5KAU A;  1D5Y A; 
#chains in the Genus database with same CATH homology
 2BOW A;  3B49 A;  3GK6 A;  3D6Z A;  5KAX A;  5KCB A;  3Q1M A;  1EXJ A;  5GQQ A;  1BOW A;  3E0H A;  2KCU A;  3D6Y A;  4A1M A;  5KAT A;  1R8E A;  1JYH A;  3LUR A;  5KAW A;  3Q5S A;  2HVA A;  3Q5P A;  1EXI A;  3R8K A;  3Q3D A;  3D70 A;  3Q5R A;  4AYZ A;  2GOV A;  4B0Y A;  4AYZ B;  3IAO A;  3D71 A;  3R8J A;  5KAV A;  3Q2Y A;  5KAU A;  1D5Y A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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